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Thematische Bibliographien / Simulated physiological solution

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Auswahl der wissenschaftlichen Literatur zum Thema „Simulated physiological solution“

Autor: Grafiati

Veröffentlicht am 28. Juni 2021

Zuletzt aktualisiert am 1. Februar 2022

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Zeitschriftenartikel zum Thema "Simulated physiological solution"

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Kocijan, A., I. Milošev, D. K. Merl und B. Pihlar. „Electrochemical Study of Co-Based Alloys in Simulated Physiological Solution“. Journal of Applied Electrochemistry 34, Nr. 5 (Mai 2004): 517–24. http://dx.doi.org/10.1023/b:jach.0000021868.10122.96.

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Frangini, S., Corrado Piconi, A. di Bartolomeo und Giuseppe Magnani. „Transformation Kinetics of Y-TZP Zirconia Ceramics in Simulated Physiological Solution“. Key Engineering Materials 192-195 (September 2000): 557–60. http://dx.doi.org/10.4028/www.scientific.net/kem.192-195.557.

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Pound, Bruce G. „Electrochemical behavior of cobalt-chromium alloys in a simulated physiological solution“. Journal of Biomedical Materials Research Part A 94A, Nr. 1 (02.02.2010): 93–102. http://dx.doi.org/10.1002/jbm.a.32684.

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Bahraminasab, Marjan, Mansoor Bozorg, Somaye Ghaffari und Fatemeh Kavakebian. „Corrosion of Al2O3-Ti composites under inflammatory condition in simulated physiological solution“. Materials Science and Engineering: C 102 (September 2019): 200–211. http://dx.doi.org/10.1016/j.msec.2019.04.047.

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Cantuária Figueiredo, Josiane, Elson Junior Souza da Silva, Jorge Luiz Rodrigues Barbosa, Jéssica Mengue Rolim, Amanda Martins Silva und Lilian Vanussa Madruga de Tunes. „Physiological performance of common bean seeds of the black commercial group under saline stress“. COLLOQUIUM AGRARIAE 17, Nr. 2 (16.04.2021): 59–66. http://dx.doi.org/10.5747/ca.2021.v17.n2.a430.

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Saline stress is a condition that causes changes in physiological performance in several species and even in cultivars of the same species. Thus, this studyaimed to evaluate the physiological performance of black bean cultivars to salt stress. A completely randomized experimental design was used in a factorial scheme with two cultivars (Mataço and BRS Paisano) and five osmotic potentials simulated with sodium chloride solutions (control = 0.0; -0.2; -0.4; -0.6 and -0.8 MPa), in four replications of 50 seeds per treatment. The variables related to germination, first germination count, germination speed index, and shoot length were evaluated. There were significant interactions (p <0.05) for all variables analyzed. In general, it is concluded that the physiological performance of the seeds of black bean cultivars is affected under simulated saline stress by NaCl solution with an osmotic potential below -0.2 MPa.

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Yazdani, Meghdad, Abdollah Afshar, Namdar Mohammadi und Behrooz Paranj. „Electrochemical evaluation of AZ 31 magnesium alloy in two simulated biological solutions“. Anti-Corrosion Methods and Materials 64, Nr. 1 (03.01.2017): 103–8. http://dx.doi.org/10.1108/acmm-02-2016-1649.

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Purpose This paper aims to investigate the corrosion behavior of AZ31 alloy as a prospective biomedical implant in two different simulated biological solutions and various immersion times. Design/methodology/approach Results of electrochemical experiments indicated that corrosion resistance of specimens immersed for 24 h was superior, suggesting that the surface layer is capable of protecting alloy. Findings Scanning electron micrographs revealed that this layer abounds with cracks, exhibiting optimum quality in 24 h immersion time, after which it begins to develop corrosion pits. Energy dispersive spectroscopy analysis suggested that the layer is mainly composed of magnesium hydroxide with precipitates of P and Ca containing species present on its surface, which is an indication of biocompatibility. Originality/value Finally, corrosion performance of Mg alloy was found to be slightly better in Lac-simulated biological solution (SBF) solution, which is more representative of actual physiological environment as compared to conventional SBF solutions.

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Silva, R. A., M. A. Barbosa, R. Vilar, O. Conde, M. Da Cunha Belo und I. Sutherland. „Electrochemical studies of laser-treated Co-Cr-Mo alloy in a simulated physiological solution“. Journal of Materials Science: Materials in Medicine 5, Nr. 6-7 (Juni 1994): 353–56. http://dx.doi.org/10.1007/bf00058962.

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Cvijović-Alagić, I., S. Laketić, J. Bajat, A. Hohenwarter und M. Rakin. „Grain refinement effect on the Ti-45Nb alloy electrochemical behavior in simulated physiological solution“. Surface and Coatings Technology 423 (Oktober 2021): 127609. http://dx.doi.org/10.1016/j.surfcoat.2021.127609.

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Pohrelyuk, I. M., O. V. Tkachuk und R. V. Proskurnyak. „Corrosion Behaviour of Ti-6Al-4V Alloy with Nitride Coatings in Simulated Body Fluids at 36∘C and 40∘C“. ISRN Corrosion 2013 (11.02.2013): 1–7. http://dx.doi.org/10.1155/2013/241830.

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Nitride coatings were formed on Ti-6Al-4V alloy by thermodiffusion treatment. The corrosion-electrochemical behaviour of Ti-6Al-4V alloy with nitride coatings I and II was investigated in physiological solutions (0.9% NaCl and Tyrode's) at temperatures of 36∘C and 40∘C. It is determined that nitride coating I provides Ti-6Al-4V alloy the higher corrosion resistance in Tyrode's solution at both temperatures of solution while nitride coating II in isotonic 0.9% NaCl.

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Izquierdo, Javier, Daniel Mareci, Georgiana Bolat, Juan J. Santana, Raquel Rodríguez-Raposo, Luis C. Fernández-Mérida, Liviu Burtan, Lucia C. Trincă und Ricardo M. Souto. „Improvement of the Corrosion Resistance of Biomedical Zr-Ti Alloys Using a Thermal Oxidation Treatment“. Metals 10, Nr. 2 (22.01.2020): 166. http://dx.doi.org/10.3390/met10020166.

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Binary Zr-Ti alloys spontaneously develop a tenacious and compact oxide layer when their fresh surface is exposed either to air or to aqueous environments. Electrochemical impedance spectroscopy (EIS) analysis of Zr-45Ti, Zr-25Ti, and Zr-5Ti exposed to simulated physiological solutions at 37 °C evidences the formation of a non-sealing bilayer oxide film that accounts for the corrosion resistance of the materials. Unfortunately, these oxide layers may undergo breakdown and stable pitting corrosion regimes at anodic potentials within the range of those experienced in the human body under stress and surgical conditions. Improved corrosion resistance has been achieved by prior treatment of these alloys using thermal oxidation in air. EIS was employed to measure the corrosion resistance of the Zr-Ti alloys in simulated physiological solutions of a wide pH range (namely 3 ≤ pH ≤ 8) at 37 °C, and the best results were obtained for the alloys pre-treated at 500 °C. The formation of the passivating oxide layers in simulated physiological solution was monitored in situ using scanning electrochemical microscopy (SECM), finding a transition from an electrochemically active surface, characteristic of the bare metal, to the heterogeneous formation of oxide layers behaving as insulating surfaces towards electron transfer reactions.

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Dissertationen zum Thema "Simulated physiological solution"

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Pewsey, Emma Jayne. „The effect of brief electrical pulses on the passivation of 316L stainless steel in simulated physiological solution“. Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.709299.

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Holubářová, Michaela. „Vliv hyaluronové kyseliny na korozi hořčíkové slitiny AZ31“. Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2021. http://www.nusl.cz/ntk/nusl-445135.

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Magnesium and its alloys are interesting materials due to their many physical properties. They have considerable potential, especially in medical applications, where they can serve as a material for the production of orthopedic and cardiovascular implants. The disadvantage of these materials is their sensitivity to corrosion. As a result, it is necessary to know the corrosive properties of magnesium and its alloys in contact with substances that occur in the human body. Hyaluronan is a polysaccharide that is naturally present in the human body and can interact with implants. This master's thesis deals with the influence of low molecular weight (80–130 kDa) and high molecular weight (1 500–1 750 kDa) hyaluronan on the corrosion properties of magnesium alloy AZ31 in the environment of two simulated physiological solutions (0,9 % NaCl and synovial fluid). Potentiodynamic polarization (PD) and electrical impedance spectroscopy (EIS) were used for electrochemical tests. Surface analysis was performed using X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) to reveal the chemical composition of the corrosion products and the surface morphology after corrosion.

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Hsu, Allen, und 許仁哲. „The dissolution of different calcium phosphate cements in simulated physiologic solution“. Thesis, 1999. http://ndltd.ncl.edu.tw/handle/73644602745395864514.

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碩士
國立成功大學
材料科學及工程學系
87
We use three kinds of synthetic calcium phosphate ceramics include of CPC、FSCPC and FSRCPC to form specimens.Make these specimens immersion in de-ionic water 、alchol、cola、pH3、5and7 Hank''s solution to simulate implant in body performance.After several immersion times we make these specimens in LVSEM, X-ray, weight-loss test and compressive strength test .We may refer the results in-vitro to in-vivo.

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Buchteile zum Thema "Simulated physiological solution"

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Hwang, Woon Suk, Seung Chan Na und Jeong Ja Lee. „Current Density Contour Map of TiNi Shape Memory Alloy in Simulated Physiological Solutions“. In Advanced Biomaterials VII, 573–76. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-436-7.573.

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Gelernter, David. „Simple Mind Machines“. In Mirror Worlds. Oxford University Press, 1991. http://dx.doi.org/10.1093/oso/9780195068122.003.0013.

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we plunge now into the deepest, trickiest, most treacherous and remarkable undersea cavern in the whole coral reef, the question of simulated experience. when we get to the bottom we will be face to face with the fundamental question of artificial intelligence (henceforth AI). we won’t know how to solve it, but we will be shining a flashlight in its face. what does it mean to think? How does thinking work? Not “how does the brain work,” but what does the thinking process consist of, in logical terms? we don’t need to understand lungs to realize that respiration has something to do with grabbing air, letting it soak in somehow and then pushing it out. Thinking is (one suspects) just as basic a physiological process as breathing; how does it work? Presumably it’s not mere random helter skelter scurrying about. There is some system at work, some process, presumably. Even when you are not hard at work solving a math problem, planning a strategy or wracking your brain for the name of someone’s daughter, there is something ticking over in there, as steadily (maybe even as rhythmically) as breathing. what is this process? As usual, we have a particular, concrete problem and a software solution in mind. The problem is crucial to Mirror worlds: How do we make the experience key work? In answering we will (again) be addressing a major problem in the non-Mirror world as well. In the last chapter, I discussed the extraction of information from fastflowing data streams at the source. we turn now to oceans of data that have accumulated in databases. what can we do with this stuff? All those multi-billions of records on file? Here, the focus is different. You don’t worry so much about extracting information fast, as the data values fly by. You focus instead on the problem of comparing many stored incidents or situations. In pursuing this concrete problem, I’ll keep the deep questions and long-term implications at bay, for the most part—but they do have a tendency to wind their tendrils around the subject matter in this chapter. I will be describing a “simulated mind” designed for a well-defined, utilitarian purpose.

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Konferenzberichte zum Thema "Simulated physiological solution"

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Danaila, Eliza, Lidia Benea und Pierre Ponthiaux. „Tribocorrosion performance of Co/UHMWPE composite biocoatings compared to pure co coatings in a simulated physiological solution“. In 2015 E-Health and Bioengineering Conference (EHB). IEEE, 2015. http://dx.doi.org/10.1109/ehb.2015.7391575.

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Benea, Lidia, Eliza Danaila, Valentin Marian Dumitrascu und Pierre Ponthiaux. „The effect of anodic oxidation treatment of Ti-10Zr alloy on tribocorrosion behavior in a simulated physiological solution“. In 2015 E-Health and Bioengineering Conference (EHB). IEEE, 2015. http://dx.doi.org/10.1109/ehb.2015.7391574.

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Nicoleta-Lucica, Anca. „THE PH VALUE EFFECT OF A SIMULATED PHYSIOLOGICAL SOLUTION ON THE CORROSION RESISTANCE OF TI-6AL-4V ALLOY“. In 17th International Multidisciplinary Scientific GeoConference SGEM2017. Stef92 Technology, 2017. http://dx.doi.org/10.5593/sgem2017/61/s24.055.

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Koff, Matthew F., Niket Shrivastava, Amy E. Abbot, Benton E. Heyworth, Thomas R. Gardner, Robert J. Strauch und Van C. Mow. „Effect of Extension Osteotomy of the 1st Metacarpal on Laxity of the Thumb Carpometacarpal Joint“. In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33029.

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Osteoarthritis (OA) of the human thumb carpometacarpal (CMC) joint is a debilitating disease. It has been proposed in the clinical literature that joint ligamentous laxity, or joint looseness, is a major etiological factor in OA of the CMC joint (Figure1) [1–4]. Previous investigations of laxity and stability of the human thumb CMC joint have been performed visually, with no quantitative measures of joint laxity recorded [5–7]. Surgical treatment has been a common solution to reduce the pain associated with CMC OA. One treatment, extension osteotomy of the 1st metacarpal, has been suggested not only to reduce the pain of OA, but also improve hand function [8], however, little is known about its biomechanical effects. A complete description of joint laxity requires that all physiological directions of motion be fully tested. A custom-designed, 4 degree of freedom tester was constructed and instrumented for displacement and load in the distraction-compression, dorsal-volar, pronation-supination, and radial-ulnar directions. The purpose of this study was to use this device to: 1) Measure the joint laxity and compliance of non-OA human thumb CMC joints and 2) Determine the effect that a simulated extension osteotomy has on joint laxity and joint stiffness. This study provides an accurate baseline for future comparisons with osteoarthritic, surgically corrected, and otherwise non-healthy CMC joints.

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Fayssal, Iyad, Fadl Moukalled, Samir Alam, Robert Habib und Hussain Ismaeel. „The Development of a Robust Low Computational Cost Diagnostic Tool to Evaluate Stenosis Functional Significance in Human Coronary Arteries“. In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51532.

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There is discordance between the anatomic severities of the coronary narrowing and their corresponding functional significance. Fractional Flow Reserve (FFR) is among the physiological parameters invasively measured to assess the hemodynamic significance of a stenosis during maximal hyperemia. FFR values ≤ 0.8 indicate that the downstream heart tissue perfused by this vessel is at risk for ischemia. While measuring FFR is an invasive procedure that is expensive, time consuming, and not without complications, recently, noninvasive estimation of FFR was shown to be possible from comprehensive predictive techniques allowing the computation of in-vivo FFR. However, these non-invasive methods are associated with high computational cost and require high performance computing technology, thus, reducing their wide adoption in clinics. This paper is steered to achieve two main goals: (1) to develop a fast numerical method to aid clinicians assessing ischemia level and determine if coronary revascularization (PCI) is required in human diseased coronary arteries with minimum time and computer resources; (2) to develop a robust method which allows predicting the patient FFR independently of the actual in-vivo physiologic conditions (mainly pressure) of the specific patient. The numerical framework was designed by adopting the finite volume method to generate the discrete model of the Reynolds average form of conservation equations used to predict blood hemodynamics. Two strategies were investigated to reduce computational cost while retaining solution accuracy. The first strategy is based on isolating the diseased artery from its branch tree and simulating it separately without implicitly integrating other arterial segments. A lumped dynamic model with special numerical treatment is coupled to the 3D domain outlet boundary to account for the downstream effects from the vascular bed. The second strategy is based on replacing a full transient simulation by a steady state one performed under mean conditions of pressure and blood volume flow rate. The strategy was applied on a healthy (hypothetical) and stenosed arterial segments with different stenosis severities simulated under rest and hyperemic conditions. An excellent agreement was achieved for FFR values computed from full transient simulations with the ones obtained from steady state simulation (error < 0.2 % was obtained for all test cases). The computational cost for the mean condition scenario was 0.1 that of a full transient simulation. The robustness of the method was tested by varying inflow conditions and reporting their effect on FFR. Interestingly, the predicted ischemia level was not altered when the inlet pressure was increased by 10 % from the base case. An analytical model was derived to explain the FFR independency of patient in-vivo coronary pressure. These promising findings from the numerical tests performed on idealized healthy and stenosed arterial models could significantly impact the applicability of the developed methodology and translating it into future practical clinical applications.

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Li, Wen, Qingjin Peng und Malcolm Xing. „Bioreactor Improvement Based on Design for Assembly in Virtual Environments“. In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-47916.

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A Bioreactor is a device used in tissue engineering to simulate the physiological environment required for cell growth, attachment, and immigration. The existing bioreactor is not user-friendly and difficult to operate. A great care has to be paid in the device application, such as assembly and disassembly in the operation. This research seeks to use design for assembly (DFA) methods to analyze and improve the design of the current bioreactor. Product difficulty levels are introduced to the DFA analysis. A new design is proposed to ease operation, save time and increase the application efficiency. The proposed solution is evaluated in a virtual environment using 3D assembly modeling and simulation.

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Yamada, Hiroshi, und Shinya Momii. „Evaluation of Possible Stress Distributions in Abdominal Aorta on the Basis of Physiologically Loading Data“. In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59683.

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It is highly desired to establish a method of estimating the stress state and mechanical properties in blood vessels numerically using diagnosis data. To obtain the mechanical state, it is necessary to evaluate the reliability of results from numerical simulation. In the current study, we investigate the possibility of stress distribution in a circular cylindrical shape of vascular wall based on the pressure-diameter relationship in the physiological pressure range with assumptions of a hyperelastic material and no residual stress. As another case, we simulate wall stress in an axisymmetric vessel at a mean pressure level. Results form the former case show that one has many solutions which reproduce the pressure-diameter (p-d) relationship and that more information is required to determine the mechanical properties. Results form the latter case show that a pair of Laplace equation and force equilibrium in the axial direction provides a wall stress for an axisymmetric shape of vessel.

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Shemesh, M., R. Asher, E. Zylberberg, F. Guilak, E. Linder-Ganz und J. J. Elsner. „Viscoelastic Properties of a Synthetic Meniscus Implant“. In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14406.

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Meniscal tears often lead to degenerative arthritis, attributed primarily to the changes in the magnitude and pattern of stress distribution in the knee. While meniscal replacement traditionally involves implantation of allografts, problems related to availability, size matching, and cost limit their use. In this regard, there are significant potential advantages to a bio-stable synthetic meniscus implant that combines long-term durability with a dependable biomechanical performance resembling that of the natural meniscus. The Nusurface ® medial Meniscus Implant is a poly-(carbonate-urethane) implant that recreates the functionality of the meniscus, as evidenced by compression tests to determine its pressure distribution capability [1] and finite element analyses [2] in its virgin state. However, the overall success of such an implant is dependent on its long-term functional properties, and biomechanical testing of the NUsurface ® device has not yet examined the effect of varying and dynamic testing conditions. In particular, the pre-test soaking in physiologic solution and the loading rate can have non-trivial influences on the properties of the device. Therefore the aims of this study were to characterize the strain-rate response, as well as the viscoelastic properties of the implant as measured by creep, stress relaxation, and hysteresis after simulated use.

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Liu, Wing Kam, und Ashfaq Adnan. „Multiscale Modeling and Simulation for Nanodiamond-Based Therapeutic Delivery“. In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13273.

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It has been demonstrated from recent research that nanodiamond(ND)-enabled drug delivery as cancer therapeutics represents an important component of optimized device functionality. The goal of the current research is to develop a multiscale modeling technique to understand the fundamental mechanism of a ND-based cancer therapeutic drug delivery system. The major components of the proposed device include nanodiamonds (ND), parylene buffer layer and doxorubicin (DOX) drugs, where DOX loaded self-assembled nanodiamonds are packed inside parylene capsule. The efficient functioning of the device is characterized by its ability to precisely detect targets (cancer cells) and then to release drugs at a controlled manner. The fundamental science issues concerning the development of the ND-based device includes (a) a precise identification of the equilibrium structure, surface electrostatics and self assembled morphology of nanodiamonds, (b) understanding of the drug/biomarker adsorption and desorption process to and from NDs, (c) rate of drug release through the parylene buffers, and finally, (d) device performance under physiological condition. In this study, we aim to systematically address these issues using a multscale computational framework. Specifically, the structure and electrostatics of the functionalized NDs are predicted by quantum scale calculation (Density Functional Tight Binding). The DFTB) study on smaller NDs suggests a facet dependent charge distributions on ND surfaces. Using the charges for smaller NDs (∼ valid for 1–3.3 nm dia ND), we then determined surface charges for larger (4–10 nm) truncated octahedral nanodiamonds (TOND). We found that the [100] face and the [111] face contain positively and negatively charged atoms, respectively. Employing this surface electrostatics of nanodiamonds, atomistic-scale simulations are performed to simulate the self-assembly process of the NDs and drug molecules in a solution as well as to evaluate nanoscale diffusion coefficient of DOX molecules. In order to quantify the nature of the aggregate morphology, a fractal analysis has been performed. The mass fractal dimensions for a variety of aggregate size have been obtained from molecular simulations assuming ‘diffusion-limited aggregation (DLA)’ process. Then, by considering the experimentally observed aggregate dimensions, by using DLA based fractal analysis and by utilizing Lagvankar-Gemmell Model for aggregate density, a continuum model for larger aggregates will be developed to characterize aggregate strengths and break-up mechanism, which in turn will help us to understand how aggregate size can be reduced. In this talk, an outline for this continuum model will be discussed. In addition, we have been performing molecular simulations on DOX-ND where multiple drug molecules are allowed to interact with a cluster of self-assembled nanodiamonds in pH controlled solution. The purpose of this study is to find the effect of solution pH on the loading and release of drug to and from nanodiamonds. Our initial results show that a higher pH is necessary to ensure drug release from nanodiamonds. Once we completely understand the essential physics of pH controlled drug loading and release, we plan to develop multiscale models of tumor nodules to represent them as a collection of individual tumor cells. Each cell will be then modeled as a deformable body comprised of three homogenous materials: cortex membrane, cytosol and nucleus. The cortex membrane and the cytosol will serve as a weak permeable medium where the absorption coefficients of the doxorubicin remain constant and obey Fick’s law. In this study, it will be assumed that drug release from the microdevice to its outer periphery will be governed by Fickian Diffusion. It will also be assumed that the complex flow of drug through the interstitial fluid of the body will be dictated by Darcy’s law. It will be assumed that the solute drug transport in these regions will be due to a combination of convection, diffusion, elimination in the intra- and extra-cellular space, receptive cell internalization and degradation. Results from this study will provide fundamental insight on the definitive targeting of infected cells and high resolution controlling of drug molecules.

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