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Rodriguez, Cristian G., Borja Mateos-Prieto, and Eduard Egusquiza. "Monitoring of Rotor-Stator Interaction in Pump-Turbine Using Vibrations Measured with On-Board Sensors Rotating with Shaft." Shock and Vibration 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/276796.
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Current trends in design of pump-turbines have led into higher rotor-stator interaction (RSI) loads over impeller-runner. These dynamic loads are of special interest having produced catastrophic failures in pump-turbines. Determining RSI characteristics facilitates the proposal of actions that will prevent these failures. Pressure measurements all around the perimeter of the impeller-runner are appropriate to monitor and detect RSI characteristics. Unfortunately most installed pump-turbines are not manufactured with in-built pressure sensors in appropriate positions to monitor RSI. For this reason, vibration measurements are the preferred method to monitor RSI in industry. Usually vibrations are measured in two perpendicular radial directions in bearings where valuable information could be lost due to bearing response. In this work, in order to avoid the effect of bearing response on measurement, two vibration sensors are installed rotating with the shaft. The RSI characteristics obtained with pressure measurements were compared to those determined using vibration measurements. The RSI characteristics obtained with pressure measurements were also determined using vibrations measured rotating with shaft. These RSI characteristics were not possible to be determined using the vibrations measured in guide bearing. Finally, it is recommended to measure vibrations rotating with shaft to detect RSI characteristics in installed pump-turbines as a more practical and reliable method to monitor RSI characteristics.
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Struzik, Artur, Grzegorz Juras, Bogdan Pietraszewski, and Andrzej Rokita. "Effect of drop jump technique on the reactive strength index." Journal of Human Kinetics 52, no. 1 (2016): 157–64. http://dx.doi.org/10.1515/hukin-2016-0003.
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AbstractThe basic drill of plyometric training aimed at improving lower limb power and jump height is a drop jump. This exercise can be performed using different techniques, which substantially affects jump variables. Therefore, the aim of this study was to compare the values of the reactive strength index (RSI) for countermovement drop jumps (CDJs) and bounce drop jumps (BDJs). The study was carried out in a group of 8 male youth basketball players. The tests were conducted using the AMTI BP600900 force plate to measure ground reaction forces and the Noraxon MyoMotion system to record kinematic data. Each player performed two CDJs and two BDJs from the height of 15, 30, 45 and 60 cm. The RSI was calculated as a ratio of jump height and contact time. Moreover, the RSI was determined for the amortization and take-off phases separately. Significant differences (p < 0.05) between RSI values for CDJs and BDJs were recorded for jumps from 30, 45 and 60 cm. Differences in RSI values for jumps from 15 cm were not significant. Furthermore, CDJ height values were significantly higher (p < 0.05) than the values recorded for BDJs. Times of contact, amortization and take-off during BDJs were significantly shorter (p < 0.05) than the respective values obtained for CDJs. Therefore, the use of the RSI to monitor plyometric training should be based on the drop jump technique that is commonly performed by basketball players.
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Putra, Andika Bagus Nur Rahma, M. Ihwanudin, Erwin Komara Mindarta, Poppy Puspitasari, and M. Mirza Abdillah Pratama. "Occupational Health And Safety (OHS) management for employees on the risk of diseases due to the intensity of computer use in the workplace/industry." MATEC Web of Conferences 204 (2018): 01016. http://dx.doi.org/10.1051/matecconf/201820401016.
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The research objectives of this study are: (1) urgent problems faced by employees when using computers; (2) computer components at risk of causing physical illness; and (3) mapping of disease experienced by OHS related employees on the computer. The subjects of this study are employees in three places of work / industry how many in Malang that work with computers with a duration of at least nine hours per day. The results of this study include: 1) the urgent problems experienced by the employees of the computer user include comfort (60%), position / feet distance (60%), monitor position at the work table (55%), mouse position (55%), (70%), rest breaks (75%), sitting position (70%), work desk condition (15%), room condition (25%), and rest break time (35%); 2) components on the computer that are at risk of causing computer-related OHS diseases that are computer CPU box (5%), computer monitor (25%), computer keyboard (10%), computer mouse (20%), computer cables (10%), and computer desk-chairs (30%); and 3) high-risk diseases suffered by employees of computer users include sicca-syndrome (55%), astenopia (70%), headache-comp (85%), Repetitive Strain Injuries (RSI) syndrom (55%), and Carpal tunnel syndrome (30%).
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García-Ávila, Fernando, Lía Ramos-Fernández, and César Zhindón-Arévalo. "Estimation of corrosive and scaling trend in drinking water systems in the city of Azogues, Ecuador." Ambiente e Agua - An Interdisciplinary Journal of Applied Science 13, no. 5 (2018): 1. http://dx.doi.org/10.4136/ambi-agua.2237.
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The quality of drinking water flowing in a distribution network can possess corrosive characteristics that may cause the material degradation of pipes and accessories. This problem can result in reduction of the service life of pipes and create a major public health problem. The agreement between the physical-chemical water quality analysis and national standards are not enough to confirm the balance of the water quality in terms of corrosion. In order to predict pipe corrosion in water distribution system networks, the corrosive trend was evaluated using the Langelier (LSI), Ryznar (RSI), and Larson-Skold (LRI) indexes based on measurements of pH, temperature, total dissolved solids, alkalinity, calcium hardness, sulfate and chloride. This study was setup with 180 samples collected in six zones of the distribution network, from July to December of 2017, according to the standard methods for the analysis of drinking water. The results indicate a variation of the LSI from -1.22 to -1.68; RSI from 9.75 to 10.52 and LRI from 0.46 to 0.77. A linear model was fitted for each index to predict the corrosion with the water quality conditions of this study case. Therefore, the drinking water of the city of Azogues, Ecuador has a corrosive tendency from significant to severe. Corrosion indices were calculated to provide useful information on the water's corrosiveness. These results indicate the need to constantly monitor the corrosion rate in the distribution network and conduct a laboratory study to adjust effective parameters such as pH, in order to control corrosion.
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Qi, Haixia, Bingyu Zhu, Lingxi Kong, et al. "Hyperspectral Inversion Model of Chlorophyll Content in Peanut Leaves." Applied Sciences 10, no. 7 (2020): 2259. http://dx.doi.org/10.3390/app10072259.
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The purpose of this study is to determine a method for quickly and accurately estimating the chlorophyll content of peanut plants at different plant densities. This was explored using leaf spectral reflectance to monitor peanut chlorophyll content to detect sensitive spectral bands and the optimum spectral indicators to establish a quantitative model. Peanut plants under different plant density conditions were monitored during three consecutive growth periods; single-photon avalanche diode (SPAD) and hyperspectral data derived from the leaves under the different plant density conditions were recorded. By combining arbitrary bands, indices were constructed across the full spectral range (350–2500 nm) based on blade spectra: the normalized difference spectral index (NDSI), ratio spectral index (RSI), difference spectral index (DSI) and soil-adjusted spectral index (SASI). This enabled the best vegetation index reflecting peanut-leaf SPAD values to be screened out by quantifying correlations with chlorophyll content, and the peanut leaf SPAD estimation models established by regression analysis to be compared and analyzed. The results showed that the chlorophyll content of peanut leaves decreased when plant density was either too high or too low, and that it reached its maximum at the appropriate plant density. In addition, differences in the spectral reflectance of peanut leaves under different chlorophyll content levels were highly obvious. Without considering the influence of cell structure as chlorophyll content increased, leaf spectral reflectance in the visible (350–700 nm): near-infrared (700–1300 nm) ranges also increased. The spectral bands sensitive to chlorophyll content were mainly observed in the visible and near-infrared ranges. The study results showed that the best spectral indicators for determining peanut chlorophyll content were NDSI (R520, R528), RSI (R748, R561), DSI (R758, R602) and SASI (R753, R624). Testing of these regression models showed that coefficient of determination values based on the NDSI, RSI, DSI and SASI estimation models were all greater than 0.65, while root mean square error values were all lower than 2.04. Therefore, the regression model established according to the above spectral indicators was a valid predictor of the chlorophyll content of peanut leaves.
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Chaabene, Helmi, Olaf Prieske, Melanie Lesinski, Ingo Sandau, and Urs Granacher. "Short-Term Seasonal Development of Anthropometry, Body Composition, Physical Fitness, and Sport-Specific Performance in Young Olympic Weightlifters." Sports 7, no. 12 (2019): 242. http://dx.doi.org/10.3390/sports7120242.
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The aim of this study is to monitor short-term seasonal development of young Olympic weightlifters’ anthropometry, body composition, physical fitness, and sport-specific performance. Fifteen male weightlifters aged 13.2 ± 1.3 years participated in this study. Tests for the assessment of anthropometry (e.g., body-height, body-mass), body-composition (e.g., lean-body-mass, relative fat-mass), muscle strength (grip-strength), jump performance (drop-jump (DJ) height, countermovement-jump (CMJ) height, DJ contact time, DJ reactive-strength-index (RSI)), dynamic balance (Y-balance-test), and sport-specific performance (i.e., snatch and clean-and-jerk) were conducted at different time-points (i.e., T1 (baseline), T2 (9 weeks), T3 (20 weeks)). Strength tests (i.e., grip strength, clean-and-jerk and snatch) and training volume were normalized to body mass. Results showed small-to-large increases in body-height, body-mass, lean-body-mass, and lower-limbs lean-mass from T1-to-T2 and T2-to-T3 (∆0.7–6.7%; 0.1 ≤ d ≤ 1.2). For fat-mass, a significant small-sized decrease was found from T1-to-T2 (∆13.1%; d = 0.4) and a significant increase from T2-to-T3 (∆9.1%; d = 0.3). A significant main effect of time was observed for DJ contact time (d = 1.3) with a trend toward a significant decrease from T1-to-T2 (∆–15.3%; d = 0.66; p = 0.06). For RSI, significant small increases from T1-to-T2 (∆9.9%, d = 0.5) were noted. Additionally, a significant main effect of time was found for snatch (d = 2.7) and clean-and-jerk (d = 3.1) with significant small-to-moderate increases for both tests from T1-to-T2 and T2-to-T3 (∆4.6–11.3%, d = 0.33 to 0.64). The other tests did not change significantly over time (0.1 ≤ d ≤ 0.8). Results showed significantly higher training volume for sport-specific training during the second period compared with the first period (d = 2.2). Five months of Olympic weightlifting contributed to significant changes in anthropometry, body-composition, and sport-specific performance. However, hardly any significant gains were observed for measures of physical fitness. Coaches are advised to design training programs that target a variety of fitness components to lay an appropriate foundation for later performance as an elite athlete.
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Ni, Yang, Li, Zhao, and He. "Decreasing Trend of Geohazards Induced by the 2008 Wenchuan Earthquake Inferred from Time Series NDVI Data." Remote Sensing 11, no. 19 (2019): 2192. http://dx.doi.org/10.3390/rs11192192.
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The occurrence of aftershocks and geohazards (landslides, collapses, and debris flows) decreases with time following a major earthquake. The 12 May 2008 Wenchuan Earthquake in Sichuan, China, provides the opportunity to characterize the subsequent spatiotemporal evolution of geohazards. Following the 12 May 2008 Wenchuan Earthquake, the incidence of geohazards first increased sharply, representing a “post-earthquake effect”, before starting to decrease. We compared the spatial distribution of the area affected by vegetation damage (AVD) triggered by large and medium-scale geohazards (LMG). We studied the interval prior to the 12 May 2008 Wenchuan Earthquake (2001–2007), the co-seismic period (2008), and the post-earthquake interval (2009–2016) and characterized the trend of decreasing geohazards at a macro scale. In vegetated areas, geohazards often seriously damage the vegetation, resulting in pronounced contrasts with the surrounding surface in terms of color tone, texture, morphology, and Normalized Difference Vegetation Index (NDVI) which are evident in remote sensing images (RSI). In principle, it is possible to use the strong positive correlation between AVD and geohazards to determine indirectly the resulting vegetation and to monitor its spatiotemporal evolution. In this study we attempted to characterize the process of geohazard evolution in the region affected by the 12 May 2008 Wenchuan Earthquake during 2001–2016. Our approach was to analyze the characteristics of areas with reduced vegetation coverage caused by LMG. Our principal findings are as follows: (i) Before the Wenchuan Earthquake (during 2001–2007), there was no evidence for a linear increase in the number of LMG with time; thus, the geological environment was relatively stable and the geohazards were mainly induced by rainfall events. (ii) The 12 May 2008 Wenchuan Earthquake was the main cause of a surge in geohazards in 2008, with the characteristics of seismogenic faults and strong aftershocks determining the spatial distribution of geohazards. (iii) Following the 12 May 2008 Wenchuan Earthquake (during 2009–2016) the incidence of geohazards exhibited an oscillating pattern of attenuation, with a decreasing trend of higher-grade seismic intensity. The intensity of geohazards was related to rainfall and seismogenic faults, and also to the number, magnitude and depth of new earthquakes following the 12 May 2008 Wenchuan Earthquake. Our results provide a new perspective on the temporal pattern of attenuation of seismic geohazards, with implications for disaster prevention and mitigation and ecological restoration in the areas affected by the 12 May 2008 Wenchuan Earthquake.
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Bollu, P., P. Gurung, T. Mehta, et al. "0619 To Rely or No to Rely: Understanding the Demographics and Polysomnographic Features of False Negative Home Sleep Apnea Testing." Sleep 43, Supplement_1 (2020): A237. http://dx.doi.org/10.1093/sleep/zsaa056.616.
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Abstract Introduction The current gold standard for a definitive diagnosis of OSA is an in-center Polysomnography (PSG). Home Sleep Apnea Testing(HSAT) has become an important tool in identifying high-risk populations. One of the limitations of the study is the lack of Electroencephalographic (EEG) data. This prevents the inclusion of Respiratory Effort Related Arousals (RERAs). We attempted to identify the patients whose HSAT showed an REI of less than 5 but are at risk for having sleep apnea based on the presence of airflow and thoraco-abdominal fluctuations. Methods Patients in this study were those that underwent HSAT from September 2016 till June of 2019. The studies reviewed and interpreted by board certified Sleep Specialists. Studies were done using nox-T3 sleep monitor and Nomad portable Home Sleep Testing type III devices-Both are type 3 Portable Monitors. Only those patients whose REI in their HSAT less than 5 were included in this study. All these patients had multiple airflow fluctuations in their HSAT that raised the suspicion for the presence of RERAs. None of these patients had significant hypoxemia in the HSAT.Airflow fluctuations were defined by the presence of fluctuations in the signal in the airflow channel along with increasing thoracoabdominal channels. Those patients with REI of less than 5 and without airflow fluctuations were excluded from the study. Results A total of 178 patients were recommended to undergo an in-center polysomnogram. Of those, 92 patients completed their polysomnogram with 59 patients ending up with a diagnosis of sleep apnea while 33 did not suggesting a false negative rate of 64.13%. Of those who were positive, 39 were females while 20 were males. Both groups did not differ significantly. Females had a median BMI of 32.9(28.19 for males), a median ESS of 11(8 in males) and a median RDI of 14.8(13.25). Conclusion Our study shows that both Home Sleep apnea testing can have a high proportion of false-negative results in patients exhibiting thoraco-abdominal and airflow fluctuations. The interpreting physicians should understand the limitations of the HSAT and should have a low threshold to recommend an in-center polysomnogram. Support None.
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Leduc, Cédric, Jason Tee, Mathieu Lacome, et al. "Convergent Validity, Reliability, and Sensitivity of a Running Test to Monitor Neuromuscular Fatigue." International Journal of Sports Physiology and Performance 15, no. 8 (2020): 1067–73. http://dx.doi.org/10.1123/ijspp.2019-0319.
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Purpose: To investigate the convergent validity, reliability, and sensitivity over a week of training of a standardized running test to measure neuromuscular fatigue. Methods: Twenty male rugby union players were recruited for the study, which took place during preseason. The standardized running test consisted of four 60-m runs paced at ~5 m·s−1 with 33 seconds of recovery between trials. Data from micromechanical electrical systems were used to calculate a running-load index (RLI), which was a ratio between the mechanical load and the speed performed during runs. RLI was calculated by using either the entire duration of the run or a constant-velocity period. For each type of calculation, either an individual directional or the sum of the 3 components of the accelerometer was used. A measure of leg stiffness was used to assess the convergent validity of the RLI. Results: Unclear to large relationships between leg stiffness and RLI were found (r ranged from −.20 to .62). Regarding reliability, small to moderate (.47–.86) standardized typical errors were found. The sensitivity analysis showed that the leg stiffness presented a very likely trivial change over the course of 1 week of training, whereas RLI showed very likely small to a most likely large change. Conclusions: This study showed that RLI is a practical method to measure neuromuscular fatigue. In addition, such a methodology aligns with the constraint of elite team-sport setup due to its ease of implementation in practice.
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Lee, JuHyoung, Hyeonguk Yoon, Sungmin Lee, and Jaeheon Lee. "Resizing effect of image and ROI in using control charts to monitor image data." Korean Journal of Applied Statistics 30, no. 3 (2017): 487–501. http://dx.doi.org/10.5351/kjas.2017.30.3.487.
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Kuenze, Christopher, Caroline Lisee, Ashley Triplett, et al. "PATIENT-REPORTED AND OBJECTIVE MEASURES OF PHYSICAL ACTIVITY ARE NOT RELATED 6-MONTHS AFTER ACL RECONSTRUCTION." Orthopaedic Journal of Sports Medicine 8, no. 4_suppl3 (2020): 2325967120S0015. http://dx.doi.org/10.1177/2325967120s00156.
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Background: When measured objectively, adults with ACL reconstruction (ACLR) are 2.5 times less likely to be physically active than by their healthy counterparts. Currently, it is unclear if patient-reported physical activity (PA) is related to objectively-measured PA among high school-aged individuals with ACLR. Purpose: To evaluate the relationship between patient-reported and objectively-measured moderate-to-vigorous PA (MVPA) among high school-aged individuals 6-months after ACLR. Methods: Seventeen participants (age= 15.9±1.3 years, BMI= 24.7±5.1 kg/m2, months since surgery= 6.3±0.7, graft source= 13 hamstring autograft, 3 patellar tendon autograft, and 1 quadriceps tendon autograft, ACL-RSI= 71.3±24.3) with primary unilateral ACLR were enrolled 6±1 months after surgery as part of a prospective cohort study. Participants completed the Tegner Activity and Marx Activity Scales to assess current physical activity level. Participants also completed the International Physical Activity Questionnaire Short Form (IPAQ-SF) to assess patient-reported MVPA (min/day). Objectively-measured MVPA (min/day) and step count (steps/day) were assessed using ActiGraph GTX9-Link accelerometers worn at the hip over a period of no less than 7 days. Wear time (min/day) was validated using recommendations of Choi et al and Evenson’s child cutpoints were utilized to categorize PA as light, moderate, vigorous, or very vigorous. Relationships between objectively-measured and patient-reported measures of physical activity were assessed using partial correlations ( r) while controlling for total monitor wear-time. We also compared the number of participants who met physical activity guidelines (60 min/day MVPA) via patient-report and objective monitoring using a Fischer’s exact test. Results: Participants reported median Tegner activity levels of 5 [range: 5,9] and Marx activity scores of 16 [range: 4,16], and average IPAQ-SF MVPA of 130±80 [range: 0,300] min/day. Objectively, partipants engaged in 26±14 [9,60] min/day of MVPA and took 6140±1691 [range: 3613,9147] steps/day. Current Tegner activity level was moderately correlated to objectively-measured MVPA ( r = 0.65) but Marx Activity Score ( r= 0.14) and IPAQ-SF MVPA ( r= 0.01) were not related to objectively-measured MVPA (Figure 1). Individuals who reported meeting MVPA guidelines were no more likely to actually meet objectively-measured MVPA guidelines as compared to participants who reported not meeting guidelines (OR= 1.08, CI= 0.93,1.25, p= 0.99). Conclusion: Objectively, 5.9% of participants were categorized as physically active 6-months following ACLR despite the fact that 82.4% of participants reported meeting PA guidelines. The relationship between objective and patient-reported measures of PA among high school-aged participants months post-ACLR is limited and utilization of patient-reported PA measures in this population should be done with caution. [Figure: see text]
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Montebugnoli, S., M. Cecchi, C. Bortolotti, M. Roma, and S. Mariotti. "RFI Sentinel 2." Symposium - International Astronomical Union 196 (2001): 301–6. http://dx.doi.org/10.1017/s0074180900164265.
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Nowadays we have a massively increasing use of radio techniques in a wide variety of application fields. Meanwhile state-of-the-art receiver technology dramatically increases the sensitivity of modern radio telescopes. This situation produces a worrying vulnerability of ground-based radio telescopes to Radio Frequency Interference (RFI). In order to monitor the RFI scenario within the frequency bands reserved for radio astronomy activities, a monitoring system, based on a quite new approach, has been developed and is presented here.
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Park, Sang-Hyun, Ki-Yeol Seo, Deuk-Jae Cho, and Sang-Hyun Suh. "A Study on Design of Reference Stations and Integrity Monitors for Maritime DGPS Recapitalization." Journal of Korean navigation and port research 33, no. 10 (2009): 691–97. http://dx.doi.org/10.5394/kinpr.2009.33.10.691.
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Silberstein, David S., David B. Wolff, David A. Marks, David Atlas, and Jason L. Pippitt. "Ground Clutter as a Monitor of Radar Stability at Kwajalein, RMI." Journal of Atmospheric and Oceanic Technology 25, no. 11 (2008): 2037–45. http://dx.doi.org/10.1175/2008jtecha1063.1.
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Abstract There are many applications in which the absolute and day-to-day calibrations of radar sensitivity are necessary. This is particularly so in the case of quantitative radar measurements of precipitation. While fine calibrations may be made periodically by a variety of techniques such as the use of antenna ranges, standard targets, and solar radiation, knowledge of variations that occur between such checks is required to maintain the accuracy of the data. This paper presents a method for this purpose using the radar on Kwajalein Atoll to provide a baseline calibration for the control of measurements of rainfall made by the Tropical Rainfall Measuring Mission (TRMM). The method uses echoes from a multiplicity of ground targets. The daily average clutter echoes at the lowest elevation scan have been found to be remarkably stable from hour to hour, day to day, and month to month within better than ±1 dB. They vary significantly only after either deliberate system modifications, equipment failure, or other unknown causes. A cumulative distribution function (CDF) of combined precipitation and clutter reflectivity (Ze in dBZ) is obtained on a daily basis, regardless of whether or not rain occurs over the clutter areas. The technique performs successfully if the average daily area mean precipitation echoes (over the area of the clutter echoes) do not exceed 45 dBZ, a condition that is satisfied in most locales. In comparison, reflectivities associated with the most intense clutter echoes can approach 70 dBZ. Thus, the level at which the CDF reaches 95% is affected only by the clutter and reflects variations only in the radar sensitivity. Daily calculations of the CDFs have recently been made beginning with August 1999 data and are used to correct 7.5 yr of measurements, thus enhancing the integrity of the global record of precipitation observed by TRMM. The method is robust and may be applicable to other ground-based radars.
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Hansen, Nienke Lynn, Alexander Ciritsis, Jens Otto, Daniel Busch, Christiane K. Kuhl, and Nils Andreas Kraemer. "Utility of Magnetic Resonance Imaging to Monitor Surgical Meshes." Investigative Radiology 50, no. 7 (2015): 436–42. http://dx.doi.org/10.1097/rli.0000000000000148.
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Bernardi, Camila Milene Soares, Diulia Molazzane Gabert, Glaucimara de Oliveira Fagundes, and Letícia Martins Machado. "Monitoria em laboratório de práticas de enfermagem: relato de experiência." Research, Society and Development 10, no. 9 (2021): e23910917925. http://dx.doi.org/10.33448/rsd-v10i9.17925.
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Este artigo objetiva relatar a experiência de estudantes de enfermagem como monitoras de um laboratório de práticas de enfermagem de uma universidade comunitária. Trata-se de um relato de experiência, realizado por estudantes de enfermagem, referente as ações desenvolvidas no período de março de 2018 a outubro de 2020, por meio da monitoria do laboratório de práticas de enfermagem, que está vinculado ao curso de graduação em Enfermagem de uma Universidade Comunitária. As experiências sustentam-se em quatro pilares: a necessidade constante de revisão da teoria para associá-la com as atividades práticas; o aprimoramento das relações de comunicação interpessoal entre a tríade monitor-estudante-docente; o desenvolvimento prático do exercício ético profissional; e aproximação do gerenciamento do laboratório com a prática de gerenciamento em enfermagem. As ações proporcionaram a potencialização da formação crítico-reflexiva, o compartilhar de experiências na construção do processo ensino-aprendizagem e o aprimoramento das habilidades técnicas-práticas-científicas das estudantes.
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WANG, XIAO-PING, HUAI-NA YU, and TONG-SHENG CHEN. "QUANTITATIVE FRET MEASUREMENT BASED ON CONFOCAL MICROSCOPY IMAGING AND PARTIAL ACCEPTOR PHOTOBLEACHING." Journal of Innovative Optical Health Sciences 05, no. 03 (2012): 1250015. http://dx.doi.org/10.1142/s1793545812500150.
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Fluorescence resonance energy transfer (FRET) technology had been widely used to study protein–protein interactions in living cells. In this study, we developed a ROI-PbFRET method to real-time quantitate the FRET efficiency of FRET construct in living cells by combining the region of interest (ROI) function of confocal microscope and partial acceptor photobleaching. We validated the ROI-PbFRET method using GFPs-based FRET constructs including 18AA and SCAT3, and used it to quantitatively monitor the dynamics of caspase-3 activation in single live cells stably expressing SCAT3 during staurosporine (STS)-induced apoptosis. Our results for the first demonstrate that ROI-PbFRET method is a powerful potential tool for detecting the dynamics of molecular interactions in live cells.
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Fang, Ji Si, Yan Bo Zhu, and Zhi Peng Wang. "GBAS Air-Ground Irrelevant Error Monitoring Method and its Application." Advanced Materials Research 718-720 (July 2013): 976–83. http://dx.doi.org/10.4028/www.scientific.net/amr.718-720.976.
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In GBAS, multipath and RFI/noise are air-ground irrelevant errors, and they could not been removed by the pseudorange difference between the aircraft and ground station. In the paper, the relationship between the B value and air-ground irrelevant error is analyzed. Since the B values for all the ground receivers are not independent, an assistant value named C is employed. Combining the characteristics of the pseudorange corrections matrix, a new method on GBAS air-ground irrelevant error monitoring is proposed. However, the method could not distinguish between multipath and RFI. Fortunately, previous study has proposed a method for detecting RFI through integrity monitoring at a DGPS reference station. Assuming the serious multipath and RFI will not appear simultaneously, user could ascertain it is multipath or RFI causes the air-ground irrelevant errors to exceed the threshold. Simulation results validated the utility of the proposed monitor methods.
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Azevedo, Carlos Rafael Lopes de, Maria Eduarda Leão de Farias, and Camila Carlos Bezerra. "Monitoria acadêmica em uma disciplina semipresencial: relato de experiência." Research, Society and Development 9, no. 4 (2020): e39942788. http://dx.doi.org/10.33448/rsd-v9i4.2788.
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Objetivou-se neste artigo, relatar as experiências de monitoria na disciplina Gestão em Saúde e Enfermagem I, tendo em vista a educação semipresencial. Trata-se de um estudo descritivo, do tipo relato de experiência, realizado a partir da vivência de discentes na monitoria de uma disciplina semipresencial. A experiência de monitoria constituiu-se como uma iniciação à docência, em que o monitor passou a conhecer as atividades inerentes à prática docente, sob orientação. Ser monitor em uma disciplina semipresencial proporcionou conhecer de forma mais detalhada essa modalidade que proporciona flexibilidade no processo de aprendizagem, incentivo ao desenvolvimento de novas competências digitais, como a autonomia, a automotivação, a reflexão crítica, a capacidade de análise e a tomada de decisões diante de situações-problema, o trabalho em equipe, o uso de diferentes linguagens e o fazer colaborativo. Conclui-se que a experiência da monitoria contribuiu tanto para a formação acadêmica do monitor, como para o andamento da disciplina semipresencial, favorecendo a comunicação e o desenvolvimento das atividades virtuais e presenciais.
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Costa, Nataly Yuri, Armando Sequeira Penela, Laíze Rúbia Silva Corrêa, et al. "A importância da monitoria acadêmica na ascensão à carreira docente." Research, Society and Development 10, no. 3 (2021): e19710313177. http://dx.doi.org/10.33448/rsd-v10i3.13177.
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Objetivo: Relatar a experiência da monitoria acadêmica como colaboradora do desenvolvimento de habilidades da docência, segundo a perspectiva do acadêmico monitor. Método: Trata-se de um estudo descritivo, de abordagem qualitativa, do tipo relato de experiência, baseado nas vivências da monitoria acadêmica no componente curricular ‘’Histologia Humana’’ ministrada em uma Universidade Pública, localizada em Belém do Pará, abordada no primeiro semestre no curso de graduação em Enfermagem, durante os anos de 2018 e 2019. Resultados: A experiência como discente-monitor favoreceu o desenvolvimento de habilidades docentes como ministrar aula, uso de metodologias ativas no processo de ensino aprendizado; comunicação; organização; compreender sobre as responsabilidades do professor universitário; planejamento pessoal e profissional; liderança; trabalho em equipe e, principalmente, formação de vínculo e empatia com o monitorando, tornando um profissional crítico e autônomo. Conclusão: A monitoria acadêmica oportuniza ao discente-monitor aprendizados além do seu componente curricular, o qual exige atualização e estudo constante do aluno, em prol de um desempenho eficaz, junto ao docente, que supervisiona e orienta em suas funções, colaborando para o desenvolvimento de habilidades para um futuro magistério superior.
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Driver, Helen S., Effie J. Pereira, Kathryn Bjerring, et al. "Validation of the MediByte®Type 3 Portable Monitor Compared with Polysomnography for Screening of Obstructive Sleep Apnea." Canadian Respiratory Journal 18, no. 3 (2011): 137–43. http://dx.doi.org/10.1155/2011/760958.
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BACKGROUND: Portable monitors are increasingly being used as a diagnostic screening tool for obstructive sleep apnea (OSA), and in-laboratory validation of these devices with polysomnography (PSG) is required.OBJECTIVE: To assess the reliability of the MediByte (Braebon Medical Corporation, Canada) type 3 screening device compared with overnight PSG.METHODS: To cover a range of OSA severity, a consecutive series of patients wore the screening device while simultaneously undergoing PSG. Data acquired from the screener and PSG were blinded and scored separately. The number of apneas and hypopneas per hour were calculated using recording time (respiratory disturbance index [RDI]) for the MediByte device, and sleep time (apnea-hypopnea index [AHI]) for PSG.RESULTS: Data from 73 patients with a mean age of 53 years and body mass index of 32.2 kg/m2showed high measurement association between the RDI and AHI, with a Pearson correlation of 0.92, accounting for 85% of the variance. Based on Bland-Altman measurement agreement, the mean difference between the RDI and AHI (−5.9±11.2 events/h) indicated screener under-reporting. For an AHI of greater than 15 events/h, the sensitivity and specificity of the screener was 80% and 97%, respectively; for an AHI of greater than 30 events/h, the positive predictive value was 100%, while the negative predictive value was 88%.CONCLUSION: The MediByte device accurately identified patients without OSA and had a high sensitivity for moderate-to-severe OSA.
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Ruehr, M. L., D. S. Damron, and M. Bond. "Analisis of A-Kinase Anchoring Protein Interactions With PKA Using Fluorescence Resonance Energy Transfer." Microscopy and Microanalysis 6, S2 (2000): 828–29. http://dx.doi.org/10.1017/s1431927600036631.
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The clustering of components of a signaling pathway at a specific subcellular location raises the local concentration of the appropriate messengers and serves to amplify the signal. The cAMP dependent-protein kinase (PKA) pathway is regulated by compartmentalization of its components. A-kinase anchoring proteins (AKAPs) tether PKA to specific subcellular sites, thus presumably increasing substrate specificity. Phosphorylation of the type II regulatory subunit of PKA (RII) increases its affinity for AKAPs in vitro (1). The purpose of this study was to investigate whether altering the phosphorylation state of RII in live cells changes its affinity for an AKAP. Specifically, we investigated the binding kinetics between Ht31, a peptide containing the PKA binding portion of an AKAP from human thyroid (2), and RII, in response to PKA activators or inhibitors.Fluorescence resonance energy transfer (FRET) was used to monitor binding events between RII and the catalytic subunit (C) of PKA, Ht31, or Ht31P, a mutated form of Ht31 which does not bind RII.
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Biernbaum, Michael S., Brad M. Binder, and M. Deric Bownds. "Dim background light and Cerenkov radiation from 32P block reversal of rhodopsin phosphorylation in intact frog retinal rods." Visual Neuroscience 7, no. 5 (1991): 499–503. http://dx.doi.org/10.1017/s0952523800009780.
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AbstractThe phosphorylation of photoexcited rhodopsin (Rho*) is thought to inactivate this receptor by inhibiting its interaction with the GTP-binding protein transducin (Gt). Here we report that the time course of phosphorylation-dephosphorylation after bright illumination of intact rod outer and inner segments (ROS-RIS) incubated in 33Pi can be altered if the ROS-RIS are first exposed to levels of dim illumination that cause light adaptation in these ROS-RIS. The dephosphorylation of >107 phosphorylated rhodopsin molecules/ROS following a bright flash can be blocked by prior dim continuous illumination (generating 103 Rho*/ROS/s) that cumulatively bleaches ≍ 105 rhodopsin molecules/ROS. The phenomenon has not been previously noted because these low levels of light are emitted as a result of Cerenkov radiation from the 32P isotope that is usually employed to monitor rhodopsin phosphorylation. The inhibition of rhodopsin dephosphorylation by dim conditioning illumination is observed in intact ROS-RIS but is lost when ROS-RIS are electropermeabilized or fragmented.
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Hill, D., C. Gore, and S. Lee. "C-58 Reliable Change Index to Monitor Executive, Adaptive and Behavioral Functioning in Children with Perinatal Complications." Archives of Clinical Neuropsychology 34, no. 6 (2019): 1087. http://dx.doi.org/10.1093/arclin/acz034.220.
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Abstract Objective Research demonstrates that children with perinatal complications (i.e., extreme prematurity, hemorrhage, hypoxic-ischemic injury) are at increased-risk for behavior, executive functioning, and adaptive independence problems in their everyday life. The purpose of this study is to demonstrate the importance of monitoring for changes in these domains as these children reach school-age. Method The current study reviewed retrospective neuropsychological evaluations for a sample of 8 children (ages 5-10 years) evaluated in an outpatient neurodevelopmental follow-up program for children with perinatal complications. Re-evaluation was completed 1-2 years later. Children with the following standardized parent-report measures were included: Behavior Assessment System for Children (BASC-2,3), Behavior Rating Inventory of Executive Function (BRIEF, 2), and Adaptive Behavior Assessment System (ABAS-3). A reliable change index was calculated for each child to compare individual change in subscales/indices using gender/age standard error of measurement from test manuals. Results BRIEF subscale RCI values (≥ 1.96) indicated that most children showed increased problems with inhibition, shifting, working memory, and planning/organizational (range -13 to 13), whereas most showed improved emotional control (range -12 to 3). BASC indices revealed stability in behavioral and externalizing symptoms (range -3 to 2). ABAS RCI values indicated that children tended to improve across skills (range -19 to 27). Figures and tables will be displayed. Conclusions This study highlights the utility of RCI values in monitoring neuropsychological changes during the early school years, as this sample of children showed changes across several developing skills. Early identification of behavioral or adaptive deficits allows providers to make recommendations for clinical management and academic planning.
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OIiveira, Lucas Ferreira de, Camila Leão do Carmo Maia, Tatiana Menezes Noronha Panzetti, Marcelo Williams Oliveira de Souza, and Mayara Melo Galvão. "Contribuição da monitoria acadêmica de Enfermagem em clínica cirurgia sobre a perspectiva do discente-monitor." Research, Society and Development 9, no. 9 (2020): e489997374. http://dx.doi.org/10.33448/rsd-v9i9.7374.
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Objetivo: Relatar vivências de acadêmicos de enfermagem no desempenho de suas atividades de monitoria do componente curricular “Enfermagem em Clínica e Cirúrgica”, descrevendo contribuições e trabalho desenvolvido por monitores em Universidade Pública do Norte do Brasil. Metodologia: Trata-se de um estudo qualitativo e descritivo, do tipo relato de experiência, realizado a partir da vivência de discentes na monitoria do componente curricular “Enfermagem em Clínica Cirúrgica”, que, no curso de graduação em Enfermagem da Universidade, é oferecida a discentes do 5º semestre, com a carga horaria semestral de 200 horas, divididas em aulas teóricas e práticas. Resultados: Foi possível estabelecer uma aproximação maior com os conteúdos ministrados e obtidos na grade curricular do curso de graduação em enfermagem, uma vez que para exercer o papel de aluno-monitor, precisa-se apropriar dos conteúdos e buscar atualizações nas literaturas disponíveis para aproveitar a melhor experiência possível que a monitoria tem a oferecer. Conclusão: A monitoria acadêmica, estimula o aprimoramento do conhecimento técnico científico do discente-monitor, oferecendo-lhe oportunidades de diversas experiências, como a de liderança nos estudos em grupos, ensaio à docência e aprimoramento das técnicas realizadas em práticas hospitalares.
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Christ, Theodore J., and Christopher David Desjardins. "Curriculum-Based Measurement of Reading: An Evaluation of Frequentist and Bayesian Methods to Model Progress Monitoring Data." Journal of Psychoeducational Assessment 36, no. 1 (2017): 55–73. http://dx.doi.org/10.1177/0734282917712174.
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Curriculum-Based Measurement of Oral Reading (CBM-R) is often used to monitor student progress and guide educational decisions. Ordinary least squares regression (OLSR) is the most widely used method to estimate the slope, or rate of improvement (ROI), even though published research demonstrates OLSR’s lack of validity and reliability, and imprecision of ROI estimates, especially after brief duration of monitoring (6-10 weeks). This study illustrates and examines the use of Bayesian methods to estimate ROI. Conditions included four progress monitoring durations (6, 8, 10, and 30 weeks), two schedules of data collection (weekly, biweekly), and two ROI growth distributions that broadly corresponded with ROIs for general and special education populations. A Bayesian approach with alternate prior distributions for the ROIs is presented and explored. Results demonstrate that Bayesian estimates of ROI were more precise than OLSR with comparable reliabilities, and Bayesian estimates were consistently within the plausible range of ROIs in contrast to OLSR, which often provided unrealistic estimates. Results also showcase the influence the priors had estimated ROIs and the potential dangers of prior distribution misspecification.
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Yun, Youngsun, Changdon Kee, Jason Rife, Ming Luo, Sam Pullen, and Per Enge. "Detecting RFI Through Integrity Monitoring at a DGPS Reference Station." Journal of Navigation 59, no. 3 (2006): 403–22. http://dx.doi.org/10.1017/s0373463306003882.
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Because GPS is a radio navigation system which has a very low power level, it is vulnerable to RFI. Excessive RFI could cause receiver performance degradation, such as degradation of position accuracy, loss of lock and increased acquisition time. After GPS modernization plans introduce dual-frequency civil signals to mitigate ionospheric errors, RFI will remain as one of the dominant threats for differential GPS navigation systems. Examples of safety-critical civil aviation and military missions threatened by RFI include the Local Area Augmentation System (LAAS) and the Joint Precision Approach and Landing System (JPALS). This paper focuses on RFI mitigation through integrity monitoring for a DGPS system like LAAS or JPALS. The mitigation strategy consists of two parts. First, the paper develops a new RFI detection method, using a raw divergence statistic. Second, the paper investigates strategies for maintaining integrity in the case that RFI is detected.To validate the utility of the divergence-based RFI monitor, this paper takes an experimental approach. The experiments assess the performance of the divergence metric and compare it to existing alternatives for RFI detection, such as metrics for Automatic Gain Control (AGC) and carrier-to-noise ratio (C/N0). Generating a monitoring threshold for these statistics proves challenging, because the threshold depends both on the type of RFI threat (e.g. continuous wave, narrow band, wideband, pulsed) and on environmental conditions, such as temperature. As experiments illustrate, the divergence statistic resolves these limitations, as divergence directly estimates ranging source error, independent of the type of RFI threat or the environmental conditions.
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Barbosa, Daisy Flávia Souza, Carlos Jose Trindade da Rocha, and João Manoel da Silva Malheiro. "As perguntas do professor monitor na experimentação investigativa em um Clube de Ciências: Classificações e organização." Research, Society and Development 8, no. 4 (2019): e2484852. http://dx.doi.org/10.33448/rsd-v8i4.852.
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Este trabalho tem origem em uma pesquisa mais ampla, que objetiva analisar as perguntas do professor monitor para incorporação da curiosidade epistemológica, a partir do processo da experimentação investigativa almejando a alfabetização científica. Para isso, apresentamos uma classificação e organização das manifestações de perguntas no desenvolvimento de atividades experimentais investigativas em um Clube de Ciências, baseado no escopo teórico que discute os conceitos e construção de categorias teóricas para perguntas. A metodologia de abordagem qualitativa, com análise do conteúdo da construção dos dados compostos pela aplicação e condução por um professor (PM1) de uma atividade experimental de nível guiada através da Sequência de Ensino Investigativa (SEI). Os resultados nos indicam que a organização e classificação de perguntas permitem analisar adequadamente os questionamentos no ensino por investigação. Conclui-se que o estudo reforça o caráter de fazer perguntas, mediação e formação docente como estratégia para o professor monitor melhor conduzir as atividades investigativas de aprendizagem.
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Mitchell, Ron B., and James Kelly. "Outcome of adenotonsillectomy for obstructive sleep apnea in children under 3 years." Otolaryngology–Head and Neck Surgery 132, no. 5 (2005): 681–84. http://dx.doi.org/10.1016/j.otohns.2004.12.010.
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OBJECTIVE: To study the outcome of adenotonsillectomy for obstructive sleep apnea (OSA) in children less than 3 years of age. DESIGN AND SETTING: Prospective study at the University of New Mexico Children's Hospital. Children with OSA underwent pre- and postoperative full-night polysomnography (PSG). Scores were compared using a paired t test. A P-value <0.05 was considered significant. RESULTS: The study population included 20 children. Fifteen (75%) were male. The mean age was 2.2 years (range, 1.1 to 3.0). Sixteen (80%) children had medical comorbidities. Over 25% of children had postoperative complications including laryngospasm and marked desaturations. The mean preoperative respiratory distress index (RDI) was 34.1 and the mean postoperative RDI was 12.2 ( P < 0.0001). After surgery, 7 (35%) children had an RDI < 5. Thirteen (65%) had a postoperative RDI ≥ 5 indicating persistent OSA. CONCLUSION AND SIGNIFICANCE: Children under 3 years show significant improvement in RDI after adenotonsillectomy for OSA, but they may develop complications after surgery. Postoperative PSG is recommended for children under 3 years of age to monitor the severity of persistent OSA. EBM rating: B-2. (Otolaryngol Head Neck Surg 2005;132:681-684.)
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Aibinu, Ajibade A., Simon Carter, Valerie Francis, and Paulo Vaz-Serra. "Request for information frequency and their turnaround time in construction projects." Built Environment Project and Asset Management 10, no. 1 (2019): 1–15. http://dx.doi.org/10.1108/bepam-10-2018-0130.
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Purpose The purpose of this paper is to study the nature of request for information (RFIs) on construction projects by using data analytics to understand the frequency of RFIs, when they occur on projects, and the relationship between project characteristics and frequency of RFIs and between project characteristics and RFI turnaround time. Design/methodology/approach A data-analytic approach using RStudio and Minitab software on 168 construction project cases in Australia and New Zealand involving 1,032,949 correspondences and 53,042 RFI event records made available by Aconex, one of the world largest cloud-based project management platform. Findings Large and complex projects tend to have significantly larger number of RFI events per day and longer RFI turnaround when compared with smaller and less complex projects. Projects with fewer users per organisation recorded a higher RFI turnaround time when compared with projects with more users per organisation – users mean persons involved in managing the project using the online platform (an index of project complexity). RFIs occur early on less complex projects and occur later on more complex projects. Research limitations/implications Benchmarks of RFI incidences and turnaround time have been developed for various project characteristics and, practitioners can use them to monitor the RFI performance of projects. Organisations need to pay greater attention to staffing levels needed to handle RFIs to reduce RFI turnaround time. Originality/value A data-analytic study of RFI yielded insights for managing RFIs. The findings of previous studies on RFIs are difficult to generalise because they are based on single project case study. The influence of project characteristics on RFI frequency and RFI turnaround time is not yet known.
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B tter-Jensen, L. "Testing of Environmental Radiation Monitors using the Ris Low-Level Radiation Measurement Stations." Radiation Protection Dosimetry 92, no. 1 (2000): 109–14. http://dx.doi.org/10.1093/oxfordjournals.rpd.a033253.
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Zheng, Jie, Elizabeth Ochoa, Bernd Misselwitz, et al. "Targeted Contrast Agent Helps to Monitor Advanced Plaque During Progression: A Magnetic Resonance Imaging Study in Rabbits." Investigative Radiology 43, no. 1 (2008): 49–55. http://dx.doi.org/10.1097/rli.0b013e318155aa5a.
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Sierra, Oscar Alberto, Karel Giovanny Núñez, Fabio Nelson Acero, and David Leonardo Alonso. "Implementación del método del triple monitor para la caracterización del flujo neutrónico del reactor nuclear de investigación IAN-R1." Revista Investigaciones y Aplicaciones Nucleares, no. 2 (December 17, 2018): 35–42. http://dx.doi.org/10.32685/2590-7468/invapnuclear.2.2018.56.
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El presente trabajo describe el procedimiento llevado a cabo para la determinación preliminar de parámetros característicos del flujo de neutrones del reactor nuclear de investigación IAN- R1 (RNI IAN-R1) por medio el método del triple monitor no cubierto en la posición de irradiación de periferia del núcleo. Mediante este método se estimó el valor de flujo térmico (ϕth), el factor de simetría de flujo de neutrones epitérmicos (α) y la razón entre flujo de neutrones térmicos con respecto al flujo de neutrones epitérmicos (ƒ). Dichos parámetros fueron obtenidos mediante la irradiación de monitores de zirconio (Zr) y de una aleación de oro con aluminio (Au-Al 0,1 % Au), que fueron irradiados en las posiciones de irradiación G3 y G4 del RNI IAN-R1. Como resultado se encontraron los siguientes valores en los parámetros estimados a una potencia de operación de 30 kW, ϕth= 2,1 × 1011 cm-2 • s-1 (coeficiente de variación CV 4%), α = 0,02 (CV 83 %), y ƒ = 67 (CV 8 %). La alta variación de α se explica porque el método usa únicamente tres reacciones de captura para describir el comportamiento de los neutrones en la región epitérmica del espectro. Esta variación se puede mejorar mediante la aplicación de métodos multimonitor para la caracterización de flujo neutrónico
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Miasaki, Natanne Terumy, Mariza Fordellone Rosa Cruz, Ellen de Souza Marquez, et al. "Comparative evaluation of the glucose level in dogs and cats obtained by portable glucometer and colorimetric automated method." Research, Society and Development 9, no. 11 (2020): e4069119583. http://dx.doi.org/10.33448/rsd-v9i11.9583.
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Glucose is an essential carbohydrate for the good functioning of the organism and in normal conditions it is able to maintain the glucose in adequate levels. The glucose can be measured by the portable glucometer or by the laboratory method, which is considered the standard methodology, but with disadvantages such as cost and the necessary amount of blood. The portable glucometer shows itself to be an applicable option because it is less expensive and faster. This prospective clinical study aimed to compare and evaluate the efficiency between the OneTouch UltraMini® portable monitor and the automated colorimetric method for measuring the blood glucose concentration of 48 dogs and 20 cats. The results obtained from the mean of the portable monitor and laboratory method were 87.54 mg/dL and 94.47 mg/dL for dogs, and 85.95 mg/dL and 100 mg/dL for cats, respectively. It could be concluded that the comparison between the methods showed that the portable meter represents an excellent option for measuring blood glucose in dogs and cats.
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Otkin, Jason A., Martha C. Anderson, Christopher Hain, and Mark Svoboda. "Examining the Relationship between Drought Development and Rapid Changes in the Evaporative Stress Index." Journal of Hydrometeorology 15, no. 3 (2014): 938–56. http://dx.doi.org/10.1175/jhm-d-13-0110.1.
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Abstract In this study, the ability of a new drought metric based on thermal infrared remote sensing imagery to provide early warning of an elevated risk for drought intensification is assessed. This new metric, called the rapid change index (RCI), is designed to highlight areas undergoing rapid changes in moisture stress as inferred from weekly changes in the evaporative stress index (ESI) generated using the Atmosphere–Land Exchange Inverse (ALEXI) surface energy balance model. Two case study analyses across the central United States revealed that the initial appearance of negative RCI values indicative of rapid increases in moisture stress preceded the introduction of severe-to-exceptional drought in the U.S. Drought Monitor (USDM) by more than 4 weeks. Using data from 2000 to 2012, the probability of USDM intensification of at least one, two, or three categories over different time periods was computed as a function of the RCI magnitude. Compared to baseline probabilities, the RCI-derived probabilities often indicate a much higher risk for drought development that increases greatly as the RCI becomes more negative. When the RCI is strongly negative, many areas are characterized by intensification probabilities that are several times higher than the baseline climatology. The highest probabilities encompass much of the central and eastern United States, with the greatest increase over climatology within regions most susceptible to rapid drought development. These results show that the RCI provides useful drought early warning capabilities that could be used to alert stakeholders of an increased risk for drought development over subseasonal time scales.
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Leiter, Edward H., Peter C. Reifsnyder, Weidong Zhang, Huei-ju Pan, Qiang Xiao, and Jehangir Mistry. "Differential Endocrine Responses to Rosiglitazone Therapy in New Mouse Models of Type 2 Diabetes." Endocrinology 147, no. 2 (2006): 919–26. http://dx.doi.org/10.1210/en.2005-0839.
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Polygenic mouse models for obesity-induced type 2 diabetes (T2D) more accurately reflect the most common manifestations of the human disease. Two inbred mouse strains (NON/Lt and NZO/HlLt) separately contributed T2D susceptibility- conferring quantitative trait loci to F1 males. Although chronic administration of rosiglitazone (Rosi) in diet (50 mg/kg) effectively suppressed F1 diabetes, hepatosteatosis was an undesired side effect. Three recombinant congenic strains (designated RCS1, -2, and -10) developed on the NON/Lt background carry variable numbers of these quantitative trait loci that elicit differential weight gain and male glucose intolerance syndromes of variable severity. We previously showed that RCS1 and -2 mice responded to chronic Rosi therapy without severe steatosis, whereas RCS10 males were moderately sensitive. In contrast, another recombinant congenic strain, RCS8, responded to Rosi therapy with the extreme hepatosteatosis observed in the F1. Longitudinal changes in multiple plasma analytes, including insulin, the adipokines leptin, resistin, and adiponectin, and plasminogen activator inhibitor-1 (PAI-1) allowed profiling of the differential Rosi responses in steatosis-exacerbated F1 and RCS8 males vs. the resistant RCS1 and RCS2 or moderately sensitive RCS10. Of these biomarkers, PAI-1 most effectively predicted adverse drug responses. Unexpectedly, mean resistin concentrations were higher in Rosi-treated RCS8 and RCS10. In summary, longitudinal profiling of multiple plasma analytes identified PAI-1 as a useful biomarker to monitor for differential pharmacogenetic responses to Rosi in these new mouse models of T2D.
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Vieira, Gilberto Ramos, Letycia dos Santos Neves, Clécia Gabriela Bezerra, et al. "Monitoria acadêmica e metodologias ativas no ensino de Fisiologia: um relato de experiência." Research, Society and Development 9, no. 12 (2020): e34791211344. http://dx.doi.org/10.33448/rsd-v9i12.11344.
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A monitoria acadêmica é uma modalidade de ensino e aprendizagem que pode fazer parte do processo de formação do discente, integrando atividades de pesquisa e extensão. Essa formação pode ser auxiliada com a utilização de metodologias ativas, contribuindo para um ensino mais dinâmico e integrativo. Assim, objetiva-se relatar a experiência da monitoria com diferentes abordagens das metodologias ativas, a fim de mostrar a importância da construção do processo da aprendizagem na disciplina de Fisiologia para o curso de educação física. Os aspectos envolvidos com a experiência, mostram as aplicações das metodologias ativas na disciplina e suas contribuições nesse processo de ensino-aprendizagem. Tais aplicações foram fundamentais para elevar o êxito acadêmico dos discentes, uma vez que as problematizações, criatividades, autonomia e criticidades estimuladas pela aplicação dessas metodologias, favoreceram a uma melhor compreensão e entendimento do conteúdo pelo aluno. Dessa maneira, verificou-se que a participação do monitor com a aplicação das metodologias ativas na disciplina de Fisiologia, foi importante na formação acadêmica dos todos os envolvidos. Tanto os alunos, quanto os monitores foram estimulados a explorarem assuntos explorados na Fisiologia, de forma crítica e autônoma, contribuindo com o processo de ensino-aprendizagem da tríade: aluno-monitor-professor.
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Kochan, Kamila, David Perez-Guaita, Julia Pissang, et al. "In vivo atomic force microscopy–infrared spectroscopy of bacteria." Journal of The Royal Society Interface 15, no. 140 (2018): 20180115. http://dx.doi.org/10.1098/rsif.2018.0115.
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A new experimental platform for probing nanoscale molecular changes in living bacteria using atomic force microscopy–infrared (AFM–IR) spectroscopy is demonstrated. This near-field technique is eminently suited to the study of single bacterial cells. Here, we report its application to monitor dynamical changes occurring in the cell wall during cell division in Staphylococcus aureus using AFM to demonstrate the division of the cell and AFM–IR to record spectra showing the thickening of the septum . This work was followed by an investigation into single cells, with particular emphasis on cell-wall signatures, in several bacterial species. Specifically, mainly cell wall components from S. aureus and Escherichia coli containing complex carbohydrate and phosphodiester groups, including peptidoglycans and teichoic acid, could be identified and mapped at nanometre spatial resolution. Principal component analysis of AFM–IR spectra of six living bacterial species enabled the discrimination of Gram-positive from Gram-negative bacteria based on spectral bands originating mainly from the cell wall components. The ability to monitor in vivo molecular changes during cellular processes in bacteria at the nanoscale opens a new platform to study environmental influences and other factors that affect bacterial chemistry.
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Zhang, Li Fen, Jing Gang Li, Wu Lin Liao, and Qiu Liang Wang. "Reservoir Induced Seismicity Types in the Three Gorges Project." Advanced Materials Research 838-841 (November 2013): 1508–11. http://dx.doi.org/10.4028/www.scientific.net/amr.838-841.1508.
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Reservoir Induced Seismicity(RIS) is a common phenomenon needed to be focused in the construction and operation of water conservancy project. The Three Gorges reservoir has a digital telemetry seismic network to monitor the earthquakes in this region. According to the correlation between water impoundment and earthquakes, the reservoir induced seismicity can be divided into rapid response and delayed response. The two types can be found in the Three Gorges area as well. In 2003, soon after the first stage of water impoundment, micro earthquake swarm occurred, which is so called rapid response type and water loading is the main factor. And delayed effect is the most observed phenomenon in RIS, in which pore diffusion controls the earthquakes. Double difference relocation results show that the earthquakes can be generally divided into three regions. And the earthquakes controlled by the active faults are called tectonic type RIS, while those related with karst, landslide, etc are nontectonic type. In region A, some earthquakes are related with the Gaoqiao active fault, and some have relationship with karst. The earthquakes in region B are controlled by some coalmines, landslide, and so on. And the earthquakes in region C belong to tectonic type RIS, which have certain relationship with the Xiannvshan fault and Jiuwanxi fault. Different RIS types have different mechanisms and controlling factors, furthermore have different earthquake trending.
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Balter, Paul, Mikhail Artemyev, and Paul Zabetakis. "Methods and Challenges for the Practical Application of Crit-Line™ Monitor Utilization in Patients on Hemodialysis." Blood Purification 39, no. 1-3 (2015): 21–24. http://dx.doi.org/10.1159/000368936.
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The Crit-Line™ monitor measures relative changes in intravascular blood volume during hemodialysis. The device is also used to monitor hematocrit and oxygen saturation. Using this device to decrease fluid volume has yielded inconsistent results on outcome measures such as hospitalization rates, erythropoietin utilization, and blood pressure reduction. Through a year-long deployment of the Crit-Line™ monitor, the Renal Research Institute (RRI) has shown that outcomes can be improved even in a busy dialysis clinic with attention to the details of how the device is utilized. In this paper, we are proposing areas of focus and methods that if properly implemented should yield improved clinical outcomes. Strong physician approval and enthusiasm coupled with clinical staff support have been shown to be vital to the success of this device in improving clinical outcomes. Even in this setting, inadequately and improperly trained staff have been identified as almost insurmountable impediments to adequate Crit-Line™ use. Our studies have shown that in facilities where staff turnover is high, procedures must be implemented to engage and train new staff immediately upon their arrival on the dialysis floor. Other issues that may lead to improper use of the Crit-Line™ monitor include incorrect target weight assessments, failure of staff to properly monitor patients during the treatment, and the over dependency of saline administration for cramps.
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Costa Neto, João Moreira Da, Gabriel Menezes Rodrigues, Pollyana Linhares Sala, et al. "Organic bench model applied to surgical suture training." Research, Society and Development 9, no. 10 (2020): e3939108614. http://dx.doi.org/10.33448/rsd-v9i10.8614.
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Veterinary and human medicine students should be trained in skills necessary to perform surgical procedures. Regarding the practice of surgical sutures, the methods used include the use of various materials such as fabric device, sponge, pieces of the animals and pieces of ethylene vinyl acetate. This article proposes to use banana and eggplant to train surgical suture techniques. The work was carried out by monitors from the veterinary surgical technical discipline. These monitors performed sutures in the vegetables (green banana and eggplant) and completed a questionnaire on the method. All monitors agreed that vegetables are easy to handle. Most stated that it was a pleasant experience for not using live animals. An advantage of using vegetables is handling, including storage and disposal. Besides, they do not transmit diseases. Animal materials such as bovine tongue, and swine parts that are widely used in suture teaching, present the risk of zoonosis transmission. The proposed organic bench model (banana and eggplant) may be indicated as a complementary alternative to advanced surgical sutures training. In addition, the model in question avoids the use of animals, while respecting ethical and legal issues.
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Almohammedi, A., S. M. Kapetanaki, B. R. Wood, E. L. Raven, N. M. Storey, and A. J. Hudson. "Spectroscopic analysis of myoglobin and cytochrome c dynamics in isolated cardiomyocytes during hypoxia and reoxygenation." Journal of The Royal Society Interface 12, no. 105 (2015): 20141339. http://dx.doi.org/10.1098/rsif.2014.1339.
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Raman microspectroscopy was applied to monitor the intracellular redox state of myoglobin and cytochrome c from isolated adult rat cardiomyocytes during hypoxia and reoxygenation. The nitrite reductase activity of myoglobin leads to the production of nitric oxide in cells under hypoxic conditions, which is linked to the inhibition of mitochondrial respiration. In this work, the subsequent reoxygenation of cells after hypoxia is shown to lead to increased levels of oxygen-bound myoglobin relative to the initial levels observed under normoxic conditions. Increased levels of reduced cytochrome c in ex vivo cells are also observed during hypoxia and reoxygenation by Raman microspectroscopy. The cellular response to reoxygenation differed dramatically depending on the method used in the preceding step to create hypoxic conditions in the cell suspension, where a chemical agent, sodium dithionite, leads to reduction of cytochromes in addition to removal of dissolved oxygen, and bubbling-N 2 gas leads to displacement of dissolved oxygen only. These results have an impact on the assessment of experimental simulations of hypoxia in cells. The spectroscopic technique employed in this work will be used in the future as an analytical method to monitor the effects of varying levels of oxygen and nutrients supplied to cardiomyocytes during either the preconditioning of cells or the reperfusion of ischaemic tissue.
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Otero-Hermida, Paula, and Mónica García-Melón. "Gender Equality Indicators for Research and Innovation from a Responsible Perspective: The Case of Spain." Sustainability 10, no. 9 (2018): 2980. http://dx.doi.org/10.3390/su10092980.
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This article offers a Spanish national perspective that contributes to European Responsible Research and Innovation (RRI) monitoring initiatives. National experts involved in gender and science and technology issues, such as policymakers, gender experts, research institutions, and equality associations, among others, have proposed indicators based on participatory decision-making techniques. The results include a complete set of 52 indicators and a reduced panel of 23 indicators—the highest-ranked ones—to monitor relevant aspects that should be measured in gender dimension from an RRI perspective: differential and asymmetric socialization and education, organizational culture, substantive representation, vertical segregation, work relations, visibility of women researchers, gender perspective in research contents, gender expertise enhancement, and resources. The results offer new indicators that differ from previous indicator panels at the European and Spanish levels in relation to those aspects that should be measured and the typology of indicators preferred. Differences suggest the need for a more nuanced debate on the purpose of indicators, and the need for national contributions to RRI and to the debate on gender perspective in EU policy. Finally, the article suggests some specific traits observed in Spain that might add to the debate on the content of an RRI gender perspective in an already developed gender policy.
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Waschatko, Gustav, Nils Billecke, Sascha Schwendy, et al. "Label-free in situ imaging of oil body dynamics and chemistry in germination." Journal of The Royal Society Interface 13, no. 123 (2016): 20160677. http://dx.doi.org/10.1098/rsif.2016.0677.
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Plant oleosomes are uniquely emulsified lipid reservoirs that serve as the primary energy source during seed germination. These oil bodies undergo significant changes regarding their size, composition and structure during normal seedling development; however, a detailed characterization of these oil body dynamics, which critically affect oil body extractability and nutritional value, has remained challenging because of a limited ability to monitor oil body location and composition during germination in situ . Here, we demonstrate via in situ , label-free imaging that oil bodies are highly dynamic intracellular organelles that are morphologically and biochemically remodelled extensively during germination. Label-free, coherent Raman microscopy (CRM) combined with bulk biochemical measurements revealed the temporal and spatial regulation of oil bodies in native soya bean cotyledons during the first eight days of germination. Oil bodies undergo a cycle of growth and shrinkage that is paralleled by lipid and protein compositional changes. Specifically, the total protein concentration associated with oil bodies increases in the first phase of germination and subsequently decreases. Lipids contained within the oil bodies change in saturation and chain length during germination. Our results show that CRM is a well-suited platform to monitor in situ lipid dynamics and local chemistry and that oil bodies are actively remodelled during germination. This underscores the dynamic role of lipid reservoirs in plant development.
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Adelman, Zeev, and Leo Joskowicz. "Deformable registration and region-of-interest image reconstruction in sparse repeat CT scanning." Journal of X-Ray Science and Technology 28, no. 6 (2020): 1069–89. http://dx.doi.org/10.3233/xst-200706.
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BACKGROUND: Repeat CT scanning is ubiquitous in many clinical situations, e.g. to follow disease progression, to evaluate treatment efficacy, and to monitor interventional CT procedures. However, it incurs in cumulative radiation to the patient which can be significantly reduced by using a region of interest (ROI) and the existing baseline scan. OBJECTIVE: To obtain a high-quality reconstruction of a ROI with a significantly reduced X-ray radiation dosage that accounts for deformations. METHODS: We present a new method for deformable registration and image reconstruction inside an ROI in repeat CT scans with a highly reduced X-ray radiation dose based on sparse scanning. Our method uses the existing baseline scan data, a user-defined ROI, and a new sparse repeat scan to compute a high-quality repeat scan ROI image with a significantly reduced radiation dose. Our method first performs rigid registration between the densely scanned baseline and the sparsely scanned repeat CT scans followed by deformable registration with a low-order parametric model, both in 3D Radon space and without reconstructing the repeat scan image. It then reconstructs the repeat scan ROI without computing the entire repeat scan image. RESULTS: Our experimental results on clinical lung and liver CT scans yield a mean × 14 computation speedup and a × 7.6-12.5 radiation dose reduction, with a minor image quality loss of 0.0157 in the NRMSE metric. CONCLUSION: Our method is considerably faster than existing methods, thereby enabling intraoperative online repeat scanning that it is accurate and accounts for position, deformation, and structure changes at a fraction of the radiation dose required by existing methods.
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Kalliski, Marc, Benedikt Beisheim, Daniel Krahè, Udo Enste, Stefan Krämer, and Sebastian Engell. "Real-time resource efficiency Indicators." atp edition 58 (January 1, 2016): 64. http://dx.doi.org/10.17560/atp.v58i01-02.553.
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Operational decisions in the day-to-day business of chemical production processes can have a significant impact on the energy and material efficiency. We propose to use real-time resource efficiency indicators (REI) to accurately monitor the energy and material efficiency in real-time and subsequently to use these in decision support for the operating staff. To guide industrial users during the development of REIs, a Namur ad-hoc working group (AK) Resource Efficiency Indicators for the operational use was set up to prepare a Namur Recommendation.
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Plaza, Dominika J., Klaudia M. Orzechowska, and Krzysztof T. Ślosarek. "Effects of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan." Polish Journal of Medical Physics and Engineering 27, no. 2 (2021): 137–41. http://dx.doi.org/10.2478/pjmpe-2021-0016.
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Abstract Introduction: The aim of the study was to evaluate the influence of flattening filter (FF) and flattening filter-free (FFF) beams on small-field and large-field dose distribution using the VMAT treatment plan. Material and methods: Dose distribution calculations were performed for the VMAT technique in two locations: the larynx (small irradiation field; average 30.1 cm2) and gynecology (large irradiation field; average 173.1 cm2) using X-6MV flattening filter (FF) and flattening filter-free (FFF) beams. The following values were compared: the number of monitor units, minimum doses, average doses in PTV and maximum average doses in OaR (spinal cord – in larynx radiotherapy, bladder and rectum - in gynecological radiotherapy) and RPI (Radiation Planning Index) coefficient. Results and Discussion: The performed statistical tests indicate that there is a significant difference (p <0.05) between the number of monitor units in the irradiation of large (gynecological) fields between the FF and FFF beams. The dose distributions show no statistically significant differences between the flattening filter and flattening-free filter beams (regardless of the field size). Conclusions: Due to the smaller number of monitor units, it is recommended to use flattening filter beams (FF) for large-field radiotherapy.
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Kneepkens, Esther, Edwin Heijman, Jochen Keupp, Steffen Weiss, Klaas Nicolay, and Holger Grüll. "Interleaved Mapping of Temperature and Longitudinal Relaxation Rate to Monitor Drug Delivery During Magnetic Resonance–Guided High-Intensity Focused Ultrasound-Induced Hyperthermia." Investigative Radiology 52, no. 10 (2017): 620–30. http://dx.doi.org/10.1097/rli.0000000000000392.
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Souza, Mariana Silva, Marcos Roberto Nascimento Sousa, Luciana Aparecida da Silva, et al. "Monitoria de enfermagem da disciplina de semiologia e semiotécnica: um relato de experiência." Research, Society and Development 10, no. 3 (2021): e37310313462. http://dx.doi.org/10.33448/rsd-v10i3.13462.
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A monitoria é uma atividade que oportuniza a participação do aluno-monitor em momentos teóricos e práticos juntamente aos discentes com o objetivo de aprofundar o conteúdo e em busca de um desenvolvimento associado à prática docente. A disciplina de Semiologia e Semiotécnica por sua parte, abrange os procedimentos técnicos executados no laboratório e no carregar de toda a vida do profissional enfermeiro. Entretanto, o monitor faz-se um facilitador da aquisição de conhecimento do outro acadêmico. O presente estudo tem como objetivo relatar a experiência vivenciada frente a monitoria de Semiologia e Semiotécnica por graduandos do curso de enfermagem da Cristo Faculdade do Piauí. Trata-se de um estudo descritivo, do tipo relato de experiência. A monitoria ocorreu no período de agosto a dezembro de 2020, correspondendo ao semestre 2020/2. Foram momentos por intermédio da plataforma remota Google Meet diante dos discentes participantes. Os momentos de monitoria proporcionaram a criação de vínculo entre os monitores e alunos beneficiados pelo programa de monitoria, e isso facilitou o processo de ensino-aprendizagem da disciplina em questão. No decorrer da monitoria foi possível por intermédio da revisão contínua dos conteúdos a criação de uma base sólida de conhecimento, bem como pela busca constante de atualização de informação e o uso de tecnologias, assim sendo inferido a tamanha importância do programa de monitoria para os discentes da faculdade. A experiência representou-se como uma atividade relevante para os monitores, uma vez que possibilitou o crescimento acadêmico, profissional e pessoal, assim como podemos observar diversos ganhos ao público participante.
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Ingram, Robert. "The Christian Monitors: The Church of England and the Age of Benevolence, 1680–1730 by Brent Sirota." Restoration: Studies in English Literary Culture, 1660-1700 39, no. 1-2 (2015): 195–97. http://dx.doi.org/10.1353/rst.2015.0010.
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