Auswahl der wissenschaftlichen Literatur zum Thema „Route du Rhum“

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Zeitschriftenartikel zum Thema "Route du Rhum"

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De la Giclais, Bertrand, François Duforez, Damien Leger, Nathalie De Premorel, Alexandre Dubois und Maxime Elbaz. „Particularité du sommeil polyphasique d’après l’EEG de sommeil en mer chez 7 navigateurs de la route du Rhum“. Médecine du Sommeil 12, Nr. 1 (Januar 2015): 44. http://dx.doi.org/10.1016/j.msom.2015.01.070.

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de La Giclais, B., F. Duforez, N. de Prémorel, A. Dubois, M. Elbaz und D. Léger. „Particularités du sommeil polyphasique d’après la polysomnographie en mer chez 7 navigateurs de la route du Rhum 2014“. Médecine du Sommeil 13, Nr. 3 (September 2016): 122–27. http://dx.doi.org/10.1016/j.msom.2016.07.003.

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Chen, BD. „In vivo administration of recombinant human interleukin-1 and macrophage colony-stimulating factor (M-CSF) induce a rapid loss of M- CSF receptors in mouse bone marrow cells and peritoneal macrophages: effect of administration route“. Blood 77, Nr. 9 (01.05.1991): 1923–28. http://dx.doi.org/10.1182/blood.v77.9.1923.1923.

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Abstract Earlier studies suggested the existence of a blood-bone marrow barrier that significantly inhibits the transfer of plasma macrophage colony- stimulating factor (M-CSF) to responsive hematopoietic cells in vivo as indicated by its failure to induce a receptor downregulation in bone marrow cells. In this study, the effect of recombinant human interleukin-1 (rhuIL-1) was investigated. In vivo administration of rhuIL-1, either intraperitoneally (IP) or intravenously (IV), induced a rapid transient loss of M-CSF receptor binding activity in bone marrow cells, with a nadir occurring between 2 to 4 hours while loss of M-CSF receptors by cells in the peritoneal cavity occurred only in animals receiving rhuIL-1 via IP administration. The loss of M-CSF receptor activity after rhuIL-1 treatment was correlated with an elevated level of circulating M-CSF. However, the loss of M-CSF receptors in marrow cells was prevented by dexamethasone (Dex) treatment before rhuIL-1 administration. The fact that Dex treatment also reduced the level of circulating M-CSF after rhuIL-1 administration suggests that the inhibitory effects of IL-1 are mediated through locally produced M-CSF. Administration of rhuM-CSF at higher doses, either IV or IP, also induced a loss of M-CSF receptor of lesser degree in the marrow cells. However, the loss of M-CSF receptors by the peritoneal cells was induced only in mice receiving rhuM-CSF through IP administration. Taken together, these results indicate the existence of a unidirectional barrier that prevents the transfer of blood M-CSF and IL- 1 to peritoneal cavity but not vice versa.
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Chen, BD. „In vivo administration of recombinant human interleukin-1 and macrophage colony-stimulating factor (M-CSF) induce a rapid loss of M- CSF receptors in mouse bone marrow cells and peritoneal macrophages: effect of administration route“. Blood 77, Nr. 9 (01.05.1991): 1923–28. http://dx.doi.org/10.1182/blood.v77.9.1923.bloodjournal7791923.

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Earlier studies suggested the existence of a blood-bone marrow barrier that significantly inhibits the transfer of plasma macrophage colony- stimulating factor (M-CSF) to responsive hematopoietic cells in vivo as indicated by its failure to induce a receptor downregulation in bone marrow cells. In this study, the effect of recombinant human interleukin-1 (rhuIL-1) was investigated. In vivo administration of rhuIL-1, either intraperitoneally (IP) or intravenously (IV), induced a rapid transient loss of M-CSF receptor binding activity in bone marrow cells, with a nadir occurring between 2 to 4 hours while loss of M-CSF receptors by cells in the peritoneal cavity occurred only in animals receiving rhuIL-1 via IP administration. The loss of M-CSF receptor activity after rhuIL-1 treatment was correlated with an elevated level of circulating M-CSF. However, the loss of M-CSF receptors in marrow cells was prevented by dexamethasone (Dex) treatment before rhuIL-1 administration. The fact that Dex treatment also reduced the level of circulating M-CSF after rhuIL-1 administration suggests that the inhibitory effects of IL-1 are mediated through locally produced M-CSF. Administration of rhuM-CSF at higher doses, either IV or IP, also induced a loss of M-CSF receptor of lesser degree in the marrow cells. However, the loss of M-CSF receptors by the peritoneal cells was induced only in mice receiving rhuM-CSF through IP administration. Taken together, these results indicate the existence of a unidirectional barrier that prevents the transfer of blood M-CSF and IL- 1 to peritoneal cavity but not vice versa.
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Jie, Junwu, und Congjin Miao. „Analysis and Selection of Shipping Route in Ocean“. Journal of Physics: Conference Series 2029, Nr. 1 (01.09.2021): 012151. http://dx.doi.org/10.1088/1742-6596/2029/1/012151.

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Abstract This electronic document is a “live” template. Ocean navigation is a long-distance cross ocean navigation. There are three kinds of ocean routes in common use: great circle route, rhumb line route and mixed route. The great circle route is usually used when ships are sailing in the ocean, but sometimes in the mid latitude sea area, the rhumb line route is a choice in the mid latitude sea area. Combined with the calculation of a navigation example, this paper makes some analysis on the selection of ocean routes in mid latitude sea area, illustrates the advantages and disadvantages of these three ocean routes with data, and draws a conclusion on how to choose the routes.
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O'Day, SJ, SN Rabinowe, D. Neuberg, AS Freedman, RJ Soiffer, NA Spector, MJ Robertson, K. Anderson, M. Whelan und K. Pesek. „A phase II study of continuous infusion recombinant human granulocyte- macrophage colony-stimulating factor as an adjunct to autologous bone marrow transplantation for patients with non-Hodgkin's lymphoma in first remission“. Blood 83, Nr. 9 (01.05.1994): 2707–14. http://dx.doi.org/10.1182/blood.v83.9.2707.2707.

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Abstract Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) clearly hastens myeloid recovery in patients with relapsed hematologic malignancies undergoing autologous bone marrow transplantation (ABMT). In efforts to further improve neutrophil engraftment and shorten hospital stay in ABMT patients, rhGM-CSF was administered by a potentially more potent route (continuous infusion) to non-Hodgkin's lymphoma (NHL) patients with better BM reserve (first remission). Time to myeloid engraftment was compared with that of NHL patients treated in first remission at our institution on a similar ABMT protocol but without growth factor support (controls). Median neutrophil engraftment (absolute neutrophil count, 500 cells/microL) in first remission patients treated with rhGM-CSF was 14 days, compared with 22 days in controls (P = .0001). Hospital stays were also significantly reduced for rhGM-CSF patients (P = .0003). Platelet engraftment did not differ between the two groups. Persistent fever and generalized serositis were the primary toxicities. rhGM-CSF, delivered by this route, was efficacious but more toxic than 2-hour rhGM-CSF infusions previously reported by other investigators. Future alterations in both dose and schedule may retain comparable efficacy yet diminish toxicity.
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O'Day, SJ, SN Rabinowe, D. Neuberg, AS Freedman, RJ Soiffer, NA Spector, MJ Robertson, K. Anderson, M. Whelan und K. Pesek. „A phase II study of continuous infusion recombinant human granulocyte- macrophage colony-stimulating factor as an adjunct to autologous bone marrow transplantation for patients with non-Hodgkin's lymphoma in first remission“. Blood 83, Nr. 9 (01.05.1994): 2707–14. http://dx.doi.org/10.1182/blood.v83.9.2707.bloodjournal8392707.

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Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) clearly hastens myeloid recovery in patients with relapsed hematologic malignancies undergoing autologous bone marrow transplantation (ABMT). In efforts to further improve neutrophil engraftment and shorten hospital stay in ABMT patients, rhGM-CSF was administered by a potentially more potent route (continuous infusion) to non-Hodgkin's lymphoma (NHL) patients with better BM reserve (first remission). Time to myeloid engraftment was compared with that of NHL patients treated in first remission at our institution on a similar ABMT protocol but without growth factor support (controls). Median neutrophil engraftment (absolute neutrophil count, 500 cells/microL) in first remission patients treated with rhGM-CSF was 14 days, compared with 22 days in controls (P = .0001). Hospital stays were also significantly reduced for rhGM-CSF patients (P = .0003). Platelet engraftment did not differ between the two groups. Persistent fever and generalized serositis were the primary toxicities. rhGM-CSF, delivered by this route, was efficacious but more toxic than 2-hour rhGM-CSF infusions previously reported by other investigators. Future alterations in both dose and schedule may retain comparable efficacy yet diminish toxicity.
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Renaut, Didier. „Nouveau rapport du GIEC. La convention-cadre sur les changements climatiques. ATLAS 3 a étudié le soleil et l'atmosphère. Quand un avion en renifle d'autres. Chaos, régimes de temps et prévisibilité. Jean-Pierre Beysson nommé directeur général de MÉTÉO-FRANCE. La route du rhum 1994, ou la météorologie médiatisée“. La Météorologie 8, Nr. 9 (1995): 88. http://dx.doi.org/10.4267/2042/51946.

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Saparbayeva, Nurzipa Abubakirovna. „Biological features of Rheum wittrockii Lundstr. in the natural population of the Ketpen ridge“. Bulletin of the Karaganda University. “Biology, medicine, geography Series” 103, Nr. 3 (29.09.2021): 125–33. http://dx.doi.org/10.31489/2021bmg3/125-133.

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The article presents data on the biological characteristics of Rheum wittrockii Lundstr. on the Ketpen ridge. The aim of the study was to research the biological characteristics of the natural growth of Rh. wittrockii. Study objects are Rh. wittrockii in natural populations of the Ketpen Ridge. In June-July 2015–2017 the route-reconnaissance method of research was carried out in the northern gorges of the Ketpen ridge of the Uygur district of the Almaty region. Determination of the morphological characteristics of plant seeds was carried out according to the methodological instructions of N.L. Udolskaya (1976). Systematic monitoring of structural changes in plant organs in a large development cycle, determination of biological characteristics and structure was carried out in accordance with the instructions of A. Zhukov (2012b), Program and methodology..., (1986). The study revealed that in the gorges Ketpen Rh. wittrockii is found at altitudes above sea level (1900–3200 m). In the first year of growth, only vegetative organs develop. The development of generative shoots begins in the 2–3rd year of plant growth. The rapid growth of reproductive generative shoots is accompanied by the growth of vegetative shoots. The flowering phase lasts 7–10 days. Flowering of one individual lasts 3–5 days. The generative phase lasts 7–8 (10) years. The fruiting process lasts from midJuly to the third decade of August. The fruiting phase is 12–14 days. The growing season of the plant is 60–75 days. The seed is a triangular nutlet. Germination is underground. Sprouts have two true leaves. The underground perennial shoot system consists of a multidisciplinary caudex formed as a result of infinitely long monopodial growth due to the activity of the apical bud of the main underground shoots. Roots Rh. wittrockii are composed of basic taproots. In the underground part, tender young roots develop in the surface layer of the soil. The duration of the generative period from germination to aging is 15–16 years.
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Hsieh, Tsung-Hsuan, Qian Meng, Bing Han, Shengzheng Wang und Xuezhen Wu. „Optimization of Waypoints on the Great Circle Route Based on Genetic Algorithm and Fuzzy Logic“. Journal of Marine Science and Engineering 11, Nr. 2 (05.02.2023): 358. http://dx.doi.org/10.3390/jmse11020358.

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Determining the appropriate number and position of waypoints on a great circle route (GCR) helps to shorten the sailing distance, reduce the number of course changes, and well-approximate the GCR through a small number of rhumb line (RL) legs. In this study, a genetic algorithm-based method (i.e., the GA method) is proposed to optimize the positions of waypoints on the GCR when the number of waypoints is given. Furthermore, a fuzzy logic-based evaluation method for the number of waypoints (i.e., the FL method) is proposed to judge whether to add a new waypoint or stop the process by using the non-fixed values while considering both the number of waypoints and the remaining benefit of the GCR. According to the example demonstration results, the two methods proposed in this study can well-determine the number and position of waypoints and provide effective support for ocean route planning.
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Dissertationen zum Thema "Route du Rhum"

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Cruz, Daily Barbara Vega. „La production du rhum et du sucre à Cuba. Valorisation du patrimoine industriel de la ville de Cárdenas“. Master's thesis, Universidade de Évora, 2018. http://hdl.handle.net/10174/27743.

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Many communities in Cuba were born to support sugar cane plantations. The deactivation of most of the industries that gave birth to these communities has also gradually led to the loss of its traditions and lifestyles and identities. Today, the consequences are catastrophic for the economy, society, urbanism and culture of those territories and their inhabitants. To preserve the collective memory of these cities is now, an imperative situation. This work focusses to promote the industrial heritage of the city of Cárdenas. To achieve this objective, an exhaustive study have carried out. This study includes the analysis of a theoretical framework of European cases in the conservation and rehabilitation of industrial landscapes and heritage. Moreover, the recognition of Cuban historiography on the sugar cane industry that represented a crucial element for the success of this research. These topics have gave the basic of heritage interpretation. These analyses has given the foundations to identify key elements that allowed the creation of a program to design a cultural itinerary about rum and sugar cane productions in the city of Cárdenas. The implementation of this project should allow the community to recover its industrial culture and the creation of new social dynamics based on their history. The implementation of this project can serve also as a reference for similar cases in Cuba; Résumé: Nombreuses communautés à Cuba, sont nées pour soutenir les plantations de la canne du sucre. La désactivation de la plus part des industries qui ont donné la vie à ces communautés, ont causé aussi graduellement la perte de ses traditions et modes de vie, de ses identités culturelles ; raison pour laquelle l'intérêt de reconnaître son caractère patrimonial a également disparu. Aujourd’hui, les conséquences sont catastrophiques pas seulement aux niveaux économiques, mais aussi aux sociaux, urbains et culturels. Préserver la mémoire collective de cette ville est une situation impérative. Ce travail a pour objectif principal la valorisation du patrimoine industriel de la ville de Cárdenas. L'étude du cadre théorique, des cas européens sur la valorisation du patrimoine et la récupération des paysages industriels et l'historiographie cubaine sur l'industrie de la canne à sucre ont été réalisés. À partir de ces sujets, les bases de l'interprétation du patrimoine ont été obtenues. À la suite des recherches, la conception d’un itinéraire culturel sur la production de rhum et de sucre de canne dans la région a été proposée. La mise en œuvre de ce projet devrait permettre à la communauté de retrouver une partie de son identité, de nouvelles formes de développement durable et de servir de référence pour des cas similaires à Cuba.
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Mondon, Sylvain. „Une approche par la pratique des relations entre action, organisation et décision en contexte extrême : le cas de la course au large à la voile“. Thesis, Paris, HESAM, 2020. http://www.theses.fr/2020HESAC019.

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La problématique de la recherche porte sur les relations entre action, décision et organisation en contexte extrême pendant la recherche de performance. Ces relations sont abordées sous l’angle d’une action en train se faire en vue d’analyser la gestion de décalages temporels de pratiques décisionnelles dans une mise en perspective temporelle de l’action. Deux épisodes de course au large sont analysés au moyen d’une approche ethnométhodologique de l’activité organisée par une pratique décisionnelle en immersion au sein de l’organisation en compétition. Les décalages temporels entre la perception d’événements à enjeux et leurs traitements au sein de l’organisation sont modélisés sous la forme du phénomène décisionnel. Nous concluons que, dans un contexte extrême, la performance de l’organisation est liée à son aptitude à mettre en œuvre une pratique décisionnelle en cohérence avec les circonstances temporelles de l’action. Cet apport contribue à une théorie pratique de l’organisation
Research issue is dedicated to the relationships between action, decision and organization in extreme context during performance seeking. These relationships are approached from the point of view of an ongoing action in order to analyze time lags management in decision-making practices in a time perspective of action. Two offshore racing sample are analyzed using an ethnomethodological approach by decision-making practice of the organized activity based on an immersion within the organization during competition. Time lags between the perception of events at stake and their management within the organization are modeled in the form of decision phenomenon. We conclude that, in extreme context, organization’s performance is linked to its ability to implement a decision-making practice consistent with temporal circumstances of the action. This result contributes to a practice theory of organization
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Bücher zum Thema "Route du Rhum"

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Colas, Teura. Le tourbillon de la gloire. Paris: Arthaud, 1988.

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Elbeze, Camille, und Dominic Bourgeois. La Route du rhum : Héroïques solitaires. La Rivière, 2002.

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Collectif und Serge Messager. La Route du Rhum: 40 ans d'aventures humaines. GRUND, 2018.

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Ellen MacArthur: La Fille de l'océan. Horizon illimité, 2003.

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Colombo, Sandrine. La route des rhums. Ibis Rouge, 2002.

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