Zeitschriftenartikel zum Thema „RNA-Targeted small molecules“
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Costales, Matthew G., Haruo Aikawa, Yue Li, Jessica L. Childs-Disney, Daniel Abegg, Dominic G. Hoch, Sai Pradeep Velagapudi et al. „Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer“. Proceedings of the National Academy of Sciences 117, Nr. 5 (21.01.2020): 2406–11. http://dx.doi.org/10.1073/pnas.1914286117.
Der volle Inhalt der QuelleNagano, Konami, Takashi Kamimura und Gota Kawai. „Interaction between a fluoroquinolone derivative and RNAs with a single bulge“. Journal of Biochemistry 171, Nr. 2 (16.11.2021): 239–44. http://dx.doi.org/10.1093/jb/mvab124.
Der volle Inhalt der QuelleSun, Saisai, Jianyi Yang und Zhaolei Zhang. „RNALigands: a database and web server for RNA–ligand interactions“. RNA 28, Nr. 2 (03.11.2021): 115–22. http://dx.doi.org/10.1261/rna.078889.121.
Der volle Inhalt der QuelleTadesse, Kisanet, und Raphael I. Benhamou. „Targeting MicroRNAs with Small Molecules“. Non-Coding RNA 10, Nr. 2 (14.03.2024): 17. http://dx.doi.org/10.3390/ncrna10020017.
Der volle Inhalt der QuelleWu, Liping, Jing Pan, Vala Thoroddsen, Deborah R. Wysong, Ronald K. Blackman, Christine E. Bulawa, Alexandra E. Gould et al. „Novel Small-Molecule Inhibitors of RNA Polymerase III“. Eukaryotic Cell 2, Nr. 2 (April 2003): 256–64. http://dx.doi.org/10.1128/ec.2.2.256-264.2003.
Der volle Inhalt der QuelleAngelbello, Alicia J., Suzanne G. Rzuczek, Kendra K. Mckee, Jonathan L. Chen, Hailey Olafson, Michael D. Cameron, Walter N. Moss, Eric T. Wang und Matthew D. Disney. „Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model“. Proceedings of the National Academy of Sciences 116, Nr. 16 (29.03.2019): 7799–804. http://dx.doi.org/10.1073/pnas.1901484116.
Der volle Inhalt der QuelleAlagia, Adele, Jana Tereňová, Ruth F. Ketley, Arianna Di Fazio, Irina Chelysheva und Monika Gullerova. „Small vault RNA1-2 modulates expression of cell membrane proteins through nascent RNA silencing“. Life Science Alliance 6, Nr. 6 (10.04.2023): e202302054. http://dx.doi.org/10.26508/lsa.202302054.
Der volle Inhalt der QuelleFrancois-Moutal, Liberty, David Donald Scott und May Khanna. „Direct targeting of TDP-43, from small molecules to biologics: the therapeutic landscape“. RSC Chemical Biology 2, Nr. 4 (2021): 1158–66. http://dx.doi.org/10.1039/d1cb00110h.
Der volle Inhalt der QuelleSmola, Matthew J., Krista Marran, Sarah E. Thompson, Brittani Patterson, Roheeth K. Pavana, Caleb Sutherland, Jessica A. Sorrentino und Katherine D. Warner. „Abstract 680: Leveraging an RNA-targeting platform for the discovery of cell-active c-MYC mRNA-binding small molecules“. Cancer Research 84, Nr. 6_Supplement (22.03.2024): 680. http://dx.doi.org/10.1158/1538-7445.am2024-680.
Der volle Inhalt der QuelleMirón-Barroso, Sofía, Joana S. Correia, Adam E. Frampton, Mark P. Lythgoe, James Clark, Laura Tookman, Silvia Ottaviani et al. „Polymeric Carriers for Delivery of RNA Cancer Therapeutics“. Non-Coding RNA 8, Nr. 4 (02.08.2022): 58. http://dx.doi.org/10.3390/ncrna8040058.
Der volle Inhalt der QuelleMartín-Villamil, María, Isaías Sanmartín, Ángela Moreno und José Gallego. „Pharmacophore-Based Discovery of Viral RNA Conformational Modulators“. Pharmaceuticals 15, Nr. 6 (14.06.2022): 748. http://dx.doi.org/10.3390/ph15060748.
Der volle Inhalt der QuelleHardigan, Andrew A., Brian S. Roberts, Dianna E. Moore, Ryne C. Ramaker, Angela L. Jones und Richard M. Myers. „CRISPR/Cas9-targeted removal of unwanted sequences from small-RNA sequencing libraries“. Nucleic Acids Research 47, Nr. 14 (05.06.2019): e84-e84. http://dx.doi.org/10.1093/nar/gkz425.
Der volle Inhalt der QuelleTran, Anh Thi-Phuong, Duc Huy Vo, Audrey Di Giorgio und Maria Duca. „ID: 1083 Targeting the production of oncogenic miRNAs using synthetic small molecules“. Biomedical Research and Therapy 4, S (05.09.2017): 170. http://dx.doi.org/10.15419/bmrat.v4is.357.
Der volle Inhalt der QuellePalazzotti, Deborah, Martina Sguilla, Giuseppe Manfroni, Violetta Cecchetti, Andrea Astolfi und Maria Letizia Barreca. „Small Molecule Drugs Targeting Viral Polymerases“. Pharmaceuticals 17, Nr. 5 (20.05.2024): 661. http://dx.doi.org/10.3390/ph17050661.
Der volle Inhalt der QuelleLiu, Yuan, Mads B. Larsen, Bo Lin, Jason R. Kennerdell, Irene Alfaras, Daniel P. Camarco, Ferhan Tuncer, Toren Finkel und Bill B. Chen. „Abstract 1805: Identification of a small molecule that induces targeted protein degradation of ADAR1“. Cancer Research 83, Nr. 7_Supplement (04.04.2023): 1805. http://dx.doi.org/10.1158/1538-7445.am2023-1805.
Der volle Inhalt der QuelleAkbar, Sehrish, Yao Wei und Mu-Qing Zhang. „RNA Interference: Promising Approach to Combat Plant Viruses“. International Journal of Molecular Sciences 23, Nr. 10 (10.05.2022): 5312. http://dx.doi.org/10.3390/ijms23105312.
Der volle Inhalt der QuelleCotten, M., G. Schaffner und M. L. Birnstiel. „Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro“. Molecular and Cellular Biology 9, Nr. 10 (Oktober 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479-4487.1989.
Der volle Inhalt der QuelleCotten, M., G. Schaffner und M. L. Birnstiel. „Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro.“ Molecular and Cellular Biology 9, Nr. 10 (Oktober 1989): 4479–87. http://dx.doi.org/10.1128/mcb.9.10.4479.
Der volle Inhalt der QuelleThaper, Daksh L., Ravi Munuganti, Shaghayegh Nouruzi, Sahil Kumar, Soojin Kim, Sepideh Vahid, Olena Sivak et al. „First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer.“ Journal of Clinical Oncology 37, Nr. 7_suppl (01.03.2019): 260. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.260.
Der volle Inhalt der QuelleAla, Ugo. „Competing Endogenous RNAs, Non-Coding RNAs and Diseases: An Intertwined Story“. Cells 9, Nr. 7 (28.06.2020): 1574. http://dx.doi.org/10.3390/cells9071574.
Der volle Inhalt der QuelleRimoldi, O. J., B. Raghu, M. K. Nag und G. L. Eliceiri. „Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA“. Molecular and Cellular Biology 13, Nr. 7 (Juli 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382-4390.1993.
Der volle Inhalt der QuelleRimoldi, O. J., B. Raghu, M. K. Nag und G. L. Eliceiri. „Three new small nucleolar RNAs that are psoralen cross-linked in vivo to unique regions of pre-rRNA.“ Molecular and Cellular Biology 13, Nr. 7 (Juli 1993): 4382–90. http://dx.doi.org/10.1128/mcb.13.7.4382.
Der volle Inhalt der QuelleFei, Yue, Tünde Nyikó und Attila Molnar. „Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs“. Nucleic Acids Research 49, Nr. 4 (01.02.2021): 1900–1913. http://dx.doi.org/10.1093/nar/gkab023.
Der volle Inhalt der QuelleTao, Wei, Arif Yurdagul, Na Kong, Wenliang Li, Xiaobo Wang, Amanda C. Doran, Chan Feng et al. „siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice“. Science Translational Medicine 12, Nr. 553 (22.07.2020): eaay1063. http://dx.doi.org/10.1126/scitranslmed.aay1063.
Der volle Inhalt der QuelleRojas-Cruz, Alexis Felipe, und Clara Isabel Bermúdez-Santana. „Computational Prediction of RNA–RNA Interactions between Small RNA Tracks from Betacoronavirus Nonstructural Protein 3 and Neurotrophin Genes during Infection of an Epithelial Lung Cancer Cell Line: Potential Role of Novel Small Regulatory RNA“. Viruses 15, Nr. 8 (28.07.2023): 1647. http://dx.doi.org/10.3390/v15081647.
Der volle Inhalt der QuelleAlonso-Valenteen, Felix, Sayuri Pacheco, Dustin Srinivas, Altan Rentsendorj, David Chu, Jay Lubow, Jessica Sims et al. „HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo“. Nucleic Acids Research 47, Nr. 21 (16.10.2019): 11020–43. http://dx.doi.org/10.1093/nar/gkz900.
Der volle Inhalt der QuelleServan de Almeida, Renata, Djénéba Keita, Geneviève Libeau und Emmanuel Albina. „Control of ruminant morbillivirus replication by small interfering RNA“. Journal of General Virology 88, Nr. 8 (01.08.2007): 2307–11. http://dx.doi.org/10.1099/vir.0.82981-0.
Der volle Inhalt der QuelleGoldberg, Zelanna, Christian Maine, Gabrielle P. Dailey, Christine Domingo, Gaelle Picarda, Hunter Little, Annie Chou et al. „Abstract 6403: A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+BC“. Cancer Research 83, Nr. 7_Supplement (04.04.2023): 6403. http://dx.doi.org/10.1158/1538-7445.am2023-6403.
Der volle Inhalt der QuelleLi, Quan, Yanan Wang, Zhihui Sun, Haiyang Li und Huan Liu. „The Biosynthesis Process of Small RNA and Its Pivotal Roles in Plant Development“. International Journal of Molecular Sciences 25, Nr. 14 (12.07.2024): 7680. http://dx.doi.org/10.3390/ijms25147680.
Der volle Inhalt der QuelleAshander, Liam M., Binoy Appukuttan, Yuefang Ma, Dione Gardner-Stephen und Justine R. Smith. „Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study“. Mediators of Inflammation 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/7945848.
Der volle Inhalt der QuelleHassanzadeh, Leila, Suxiang Chen und Rakesh Veedu. „Radiolabeling of Nucleic Acid Aptamers for Highly Sensitive Disease-Specific Molecular Imaging“. Pharmaceuticals 11, Nr. 4 (15.10.2018): 106. http://dx.doi.org/10.3390/ph11040106.
Der volle Inhalt der QuelleLavender, Helen, Kevin Brady, Frances Burden, Oona Delpuech-Adams, Hubert Denise, Amy Palmer, Hannah Perkins et al. „In VitroCharacterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy“. Antimicrobial Agents and Chemotherapy 56, Nr. 3 (27.12.2011): 1364–75. http://dx.doi.org/10.1128/aac.05357-11.
Der volle Inhalt der QuelleColl-SanMartin, Laia, Veronica Davalos, David Piñeyro, Margalida Rosselló-Tortella, Alberto Bueno-Costa, Fernando Setien, Alberto Villanueva et al. „Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensitivity to Arsenic Trioxide in Small-Cell Lung Cancer“. Cancers 13, Nr. 8 (14.04.2021): 1869. http://dx.doi.org/10.3390/cancers13081869.
Der volle Inhalt der QuelleHagiwara, Shinji, Aaron McClelland und Phillip Kantharidis. „MicroRNA in Diabetic Nephropathy: Renin Angiotensin, AGE/RAGE, and Oxidative Stress Pathway“. Journal of Diabetes Research 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/173783.
Der volle Inhalt der QuelleJoshi, Mansi, Pranay Dey und Abhijit De. „Recent advancements in targeted protein knockdown technologies—emerging paradigms for targeted therapy“. Exploration of Targeted Anti-tumor Therapy 4, Nr. 6 (26.12.2023): 1227–48. http://dx.doi.org/10.37349/etat.2023.00194.
Der volle Inhalt der QuelleTidwell, Elizabeth D., Ingrid R. Kilde, Suada Leskaj und Markos Koutmos. „Fluorescent Ligand Equilibrium Displacement: A High-Throughput Method for Identification of FMN Riboswitch-Binding Small Molecules“. International Journal of Molecular Sciences 25, Nr. 2 (06.01.2024): 735. http://dx.doi.org/10.3390/ijms25020735.
Der volle Inhalt der QuelleKalynych, Sergei, Lenka Pálková und Pavel Plevka. „The Structure of Human Parechovirus 1 Reveals an Association of the RNA Genome with the Capsid“. Journal of Virology 90, Nr. 3 (18.11.2015): 1377–86. http://dx.doi.org/10.1128/jvi.02346-15.
Der volle Inhalt der QuelleShen, Linyuan, Zhendong Tan, Mailin Gan, Qiang Li, Lei Chen, Lili Niu, Dongmei Jiang et al. „tRNA-Derived Small Non-Coding RNAs as Novel Epigenetic Molecules Regulating Adipogenesis“. Biomolecules 9, Nr. 7 (11.07.2019): 274. http://dx.doi.org/10.3390/biom9070274.
Der volle Inhalt der QuelleSimba-Lahuasi, Alvaro, Ángel Cantero-Camacho, Romel Rosales, Briana Lynn McGovern, M. Luis Rodríguez, Vicente Marchán, Kris M. White, Adolfo García-Sastre und José Gallego. „SARS-CoV-2 Inhibitors Identified by Phenotypic Analysis of a Collection of Viral RNA-Binding Molecules“. Pharmaceuticals 15, Nr. 12 (22.11.2022): 1448. http://dx.doi.org/10.3390/ph15121448.
Der volle Inhalt der QuelleHarrington, Lucas B., David Burstein, Janice S. Chen, David Paez-Espino, Enbo Ma, Isaac P. Witte, Joshua C. Cofsky, Nikos C. Kyrpides, Jillian F. Banfield und Jennifer A. Doudna. „Programmed DNA destruction by miniature CRISPR-Cas14 enzymes“. Science 362, Nr. 6416 (18.10.2018): 839–42. http://dx.doi.org/10.1126/science.aav4294.
Der volle Inhalt der QuelleMourenza, Álvaro, Blanca Lorente-Torres, Elena Durante, Jesús Llano-Verdeja, Jesús F. Aparicio, Arsenio Fernández-López, José A. Gil, Luis M. Mateos und Michal Letek. „Understanding microRNAs in the Context of Infection to Find New Treatments against Human Bacterial Pathogens“. Antibiotics 11, Nr. 3 (08.03.2022): 356. http://dx.doi.org/10.3390/antibiotics11030356.
Der volle Inhalt der QuelleCrisci, Amitrano, Saggese, Muto, Sarno, Mele, Vitale, Ronga, Berretta und Di Francia. „Overview of Current Targeted Anti-Cancer Drugs for Therapy in Onco-Hematology“. Medicina 55, Nr. 8 (28.07.2019): 414. http://dx.doi.org/10.3390/medicina55080414.
Der volle Inhalt der QuelleCiccone, Giuseppe, Maria Luigia Ibba, Gabriele Coppola, Silvia Catuogno und Carla Lucia Esposito. „The Small RNA Landscape in NSCLC: Current Therapeutic Applications and Progresses“. International Journal of Molecular Sciences 24, Nr. 7 (24.03.2023): 6121. http://dx.doi.org/10.3390/ijms24076121.
Der volle Inhalt der QuelleMorais, Pedro, Rui Zhang und Yi-Tao Yu. „Therapeutic Nonsense Suppression Modalities: From Small Molecules to Nucleic Acid-Based Approaches“. Biomedicines 12, Nr. 6 (10.06.2024): 1284. http://dx.doi.org/10.3390/biomedicines12061284.
Der volle Inhalt der QuelleXiao, Fei, Chenglong Wang, Jianping Peng, Xing Zhou, Ding Ma, Yu Wang, Yanpeng Li, Xiaodong Chen und Chuandong Wang. „Changes in Small Noncoding RNA Expression during Chondrocyte Senescence“. CARTILAGE 13, Nr. 3 (Juli 2022): 194760352211181. http://dx.doi.org/10.1177/19476035221118165.
Der volle Inhalt der QuelleKakumani, Pavan Kumar, Louis-Mathieu Harvey, François Houle, Tanit Guitart, Fátima Gebauer und Martin J. Simard. „CSDE1 controls gene expression through the miRNA-mediated decay machinery“. Life Science Alliance 3, Nr. 4 (11.03.2020): e201900632. http://dx.doi.org/10.26508/lsa.201900632.
Der volle Inhalt der QuelleCunningham, Tyler A., Derek Essegian, Stephan Schürer und Jonathan H. Schatz. „Identification of Tractable Drug-like eIF4Al Inhibitors with Potent Anti-Tumor Activity“. Blood 134, Supplement_1 (13.11.2019): 5760. http://dx.doi.org/10.1182/blood-2019-130494.
Der volle Inhalt der QuelleAughton, Karen, Helen Kalirai und Sarah E. Coupland. „MicroRNAs and Uveal Melanoma: Understanding the Diverse Role of These Small Molecular Regulators“. International Journal of Molecular Sciences 21, Nr. 16 (06.08.2020): 5648. http://dx.doi.org/10.3390/ijms21165648.
Der volle Inhalt der QuelleChauhan, Waseem, Sudharshan SJ, Sweta Kafle und Rahima Zennadi. „SnoRNAs: Exploring Their Implication in Human Diseases“. International Journal of Molecular Sciences 25, Nr. 13 (29.06.2024): 7202. http://dx.doi.org/10.3390/ijms25137202.
Der volle Inhalt der QuelleUyeno, Yutaka, Yuji Sekiguchi, Akiko Sunaga, Hiroki Yoshida und Yoichi Kamagata. „Sequence-Specific Cleavage of Small-Subunit (SSU) rRNA with Oligonucleotides and RNase H: a Rapid and Simple Approach to SSU rRNA-Based Quantitative Detection of Microorganisms“. Applied and Environmental Microbiology 70, Nr. 6 (Juni 2004): 3650–63. http://dx.doi.org/10.1128/aem.70.6.3650-3663.2004.
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