Zeitschriftenartikel: „Recovery events“

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Davidson, Dennis M., und Cathy A. Maloney. „Recovery After Cardiac Events“. Physical Therapy 65, Nr. 12 (01.12.1985): 1820–27. http://dx.doi.org/10.1093/ptj/65.12.1820.

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Wang, Jianmin, Shaoxu Song, Xiaochen Zhu und Xuemin Lin. „Efficient recovery of missing events“. Proceedings of the VLDB Endowment 6, Nr. 10 (26.08.2013): 841–52. http://dx.doi.org/10.14778/2536206.2536212.

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Wang, Jianmin, Shaoxu Song, Xiaochen Zhu, Xuemin Lin und Jiaguang Sun. „Efficient Recovery of Missing Events“. IEEE Transactions on Knowledge and Data Engineering 28, Nr. 11 (01.11.2016): 2943–57. http://dx.doi.org/10.1109/tkde.2016.2594785.

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Su, Yi-Zhu, und Wei-Chang Yeh. „Binary-Addition Tree Algorithm-Based Resilience Assessment for Binary-State Network Problems“. Electronics 9, Nr. 8 (27.07.2020): 1207. http://dx.doi.org/10.3390/electronics9081207.

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Applications in real life are composed of different kinds of network systems; these networks may be interfered by uncontrollable or unpredictable disruptive events involving natural disasters, human errors, evil-intentioned attacks, or other disturbances. Any of these disruptive events will cause networks to malfunction and possibly result in large economic losses. As a result, it is important to assess network resilience which is a measure to describe how a network system recovers its performance and functionality to a satisfactory level from a disruptive event. Inspired by the measures of reliability evaluation used in binary-state networks, this paper proposes a binary-addition tree algorithm-based resilience assessment for binary-state networks and applies it on a wildfire network with wireless sensors. Considering the stochastic nature of disruptive events, the proposed binary-addition tree algorithm-based resilience assessment comprehensively enumerates all the possible disruptive events and all the corresponding recovery strategies, and then calculate the network resilience. Furthermore, recovery cost limit is concerned in this paper for decision makers who choose the recovery strategies with their recovery cost limit and resilience requirement.

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Cockbain, A. E. „Biotic recovery from mass extinction events“. Earth-Science Reviews 42, Nr. 1-2 (März 1997): 133–34. http://dx.doi.org/10.1016/s0012-8252(97)83484-8.

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Dissanayake, Pushpa, Jennifer Brown und Harshinie Karunarathna. „EFFECT OF FUTURE STORM CLUSTERING ON BEACH/DUNE EVOLUTION AND COASTAL FLOODING“. Coastal Engineering Proceedings, Nr. 35 (23.06.2017): 19. http://dx.doi.org/10.9753/icce.v35.sediment.19.

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Future storm impacts on dune evolution due to changing storm frequency were simulated in XBeach at an exemplary dune system, Formby Point, UK. Probabilistic approaches were used to establish the future storm clusters from 2015 to 2065 in three scenarios, using measured data in Liverpool Bay. Cross-shore profile simulations were carried out in two series: Recovery and Cluster. Recovery used the same initial profile assuming that the profile is fully recovered when the subsequent storm event occurs. Cluster used the modified profile from the previous storm event. Within a single event, the maximum erosion and accretion of the profile occurred under the Recovery conditions due to the presence of a pronounced nearshore ridge-runnel pattern that evolved during severe storm events. Only a few storm events impacted on the upper dune area resulting in a bed level change, which under the Cluster approach was more noticeable when compared with the Recovery approach. The inter-tidal area experienced erosion while the sub-tidal area showed accretion in both the Recovery and the Cluster approaches, and the agreement of bed level change was considerably higher than that in the upper dune area. Vulnerability of the upper dune area increases in the Cluster approach as the initial storm events flatten the nearshore ridge-runnel pattern, and then the severe storm events directly impact on the dune front. High dune elevation at Formby Point prevents lowering of the dune crest due to the storm cluster erosion and therefore it can still withstand against flooding. Spatial modelling of the dune system is required to gain more insights of erosion and flood prone areas along this coast.

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Jemni, Monèm, William A. Sands, Françoise Friemel und Paul Delamarche. „Effect of Active and Passive Recovery on Blood Lactate and Performance During Simulated Competition in High Level Gymnasts“. Canadian Journal of Applied Physiology 28, Nr. 2 (01.04.2003): 240–56. http://dx.doi.org/10.1139/h03-019.

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The purpose of this study was to investigate the effect of two recovery strategies between men's gymnastics events on blood lactate removal (BL) and performance as rated by expert "blind" judges. Twelve male gymnasts (21.8 ± 2.4 years) participated. The sessions were composed of routine performances in the six Olympic events, which were separated by 10 min of recovery. All gymnasts performed two recovery protocols between events on separate days: Rest protocol, 10 min rest in a sitting position; combined protocol, 5 min rest and 5 min self-selected active recovery. Three blood samples were taken at 2, 5, and 10 min following each event. Gymnasts produced moderate values of BL following each of the six events (2.2 to 11.6 mmolúL−1). There was moderate variability in BL values between events that could not be accounted for by the athlete's event performance. Gymnasts showed higher BL concentration (p > .05) and significantly (p < .05) higher scoring performances (as rated by a panel of certified judges) when they used a combined recovery between gymnastics events rather than a passive recovery (ΔBL = 40.51% vs. 28.76% of maximal BL, p < .05, and total score = 47.28 ± 6.82 vs. 38.39 ± 7.55, p < .05, respectively). Key words: oxidation, removal, heart rate

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Fay, Alex J., Ellen M. Mowry, Jonathan Strober und Emmanuelle Waubant. „Relapse severity and recovery in early pediatric multiple sclerosis“. Multiple Sclerosis Journal 18, Nr. 7 (19.12.2011): 1008–12. http://dx.doi.org/10.1177/1352458511431725.

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Background: Factors determining severity and recovery of early demyelinating events in pediatric multiple sclerosis (MS) patients are unknown. Objective: The objective of this study was to characterize the severity and recovery of early demyelinating events in pediatric MS. Methods: Multivariate logistic regression was performed to determine predictors of severe (versus mild/moderate) relapses and poor or fair (versus complete) recovery in patients aged 18 years or less with MS or clinically isolated syndrome (CIS). Results: Optic nerve involvement (OR 4.30, 95% CI 1.50–12.3, p = 0.007) was associated with a severe initial demyelinating event (IDE), while non-White race (OR 2.55, 95% CI 0.87–7.49, p = 0.088), localization to the cerebral hemispheres (OR 7.94, 95% CI 0.86–73.8, p = 0.068), or encephalopathy (OR 8.70, 95% CI 0.86–88.0, p = 0.067) showed a trend towards increased IDE severity. A similar association with race was found for severe second events. A severe IDE (OR 6.90, 95% CI 2.47–19.3, p < 0.001) was associated with incomplete IDE recovery, with similar trends for second and third events. Incomplete recovery from the first event predicted incomplete second event recovery (OR 3.36, 95% CI 0.98–11.6, p = 0.055). Conclusions: These results may help identify children at risk for a more aggressive disease course.

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Bailey, R., Z. Lu, S. Shirzadi und E. Ziegel. „Analyzing Well Events To Increase Oil Recovery“. Journal of Petroleum Technology 66, Nr. 08 (01.08.2014): 29–31. http://dx.doi.org/10.2118/0814-0029-jpt.

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Tinker, Jane E., und Jalie A. Tucker. „Environmental events surrounding natural recovery from obesity“. Addictive Behaviors 22, Nr. 4 (Juli 1997): 571–75. http://dx.doi.org/10.1016/s0306-4603(97)00066-x.

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Burger, Daniel C., Haney Mallemat und Ralph R. Miller. „Overshadowing of subsequent events and recovery thereafter“. Quarterly Journal of Experimental Psychology Section B 53, Nr. 2b (Mai 2000): 149–71. http://dx.doi.org/10.1080/713932724.

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Four experiments using a conditioned lick suppression preparation with rats were conducted to examine whether overshadowing of subsequent events could be obtained in Pavlovian backward conditioning (i.e. unconditioned stimulus [US] before conditioned stimulus [CS]), and to determine whether such overshadowing could be reversed without further training with the overshadowed CS, as has been reported in overshadowing of antecedent events. In Experiment 1, a backward-conditioned CS overshadowed a second backward-conditioned CS. Two posttraining manipulations, extinction of the overshadowing CS (Experiment 2) and shifting of the temporal relationship of the overshadowing CS to the US (Experiment 3), increased responding to the overshadowed CS. These results constitute the first unambiguous demonstration of stimulus competition between subsequent events using first-order conditioning, and they show that, like overshadowing with forward conditioning, such overshadowing is due, at least in part if not completely, to a failure to express information that had been acquired.

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Corbella, S., und D. D. Stretch. „Shoreline recovery from storms on the east coast of Southern Africa“. Natural Hazards and Earth System Sciences 12, Nr. 1 (02.01.2012): 11–22. http://dx.doi.org/10.5194/nhess-12-11-2012.

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Abstract. Episodic extreme waves due to sea storms can cause severe coastal erosion. The recovery times of such events are important for the analysis of risk and coastal vulnerability. The recovery period of a storm damaged coastline represents a time when the coastline is most vulnerable and nearby infrastructure is at the greatest risk. We propose that identification of the beach recovery period can be used as a coastal management tool when determining beach usage. As a case study, we analyse 37 yr of beach profile data on the east coast of South Africa. Considering beach length and cross-sectional area, we establish a global recovery period and rate and identify the physical characteristics of the coastlines that either accelerate or retard recovery. The beaches in the case study were found to take an average of two years to recover at a rate of approximately 90 m3 m−1 yr−1. Beach profiles with vegetated dunes recovered faster than urbanized beaches. Perpendicular beach structures have both positive and negative effects on beach recovery. Coastlines with rock outcrops in the surf zone tend to recover slowly and long-term sediment loss was identified in cases where storm damaged beaches have not recovered to pre-erosion levels.

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Badaro, Gilbert, Ulf Behrens, James Branson, Philipp Brummer, Sergio Cittolin, Diego Da Silva-Gomes, Georgiana-Lavinia Darlea et al. „DAQExpert the service to increase CMS data-taking efficiency“. EPJ Web of Conferences 245 (2020): 01028. http://dx.doi.org/10.1051/epjconf/202024501028.

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The Data Acquisition (DAQ) system of the Compact Muon Solenoid (CMS) experiment at the LHC is a complex system responsible for the data readout, event building and recording of accepted events. Its proper functioning plays a critical role in the data-taking efficiency of the CMS experiment. In order to ensure high availability and recover promptly in the event of hardware or software failure of the subsystems, an expert system, the DAQ Expert, has been developed. It aims at improving the data taking efficiency, reducing the human error in the operations and minimising the on-call expert demand. Introduced in the beginning of 2017, it assists the shift crew and the system experts in recovering from operational faults, streamlining the post mortem analysis and, at the end of Run 2, triggering fully automatic recovery without human intervention. DAQ Expert analyses the real-time monitoring data originating from the DAQ components and the high-level trigger updated every few seconds. It pinpoints data flow problems, and recovers them automatically or after given operator approval. We analyse the CMS downtime in the 2018 run focusing on what was improved with the introduction of automated recovery; present challenges and design of encoding the expert knowledge into automated recovery jobs. Furthermore, we demonstrate the web-based, ReactJS interfaces that ensure an effective cooperation between the human operators in the control room and the automated recovery system. We report on the operational experience with automated recovery.

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Lewin, Terry J., Vaughan J. Carr und Rosemary A. Webster. „Recovery from Post-Earthquake Psychological Morbidity: Who Suffers and who Recovers?“ Australian & New Zealand Journal of Psychiatry 32, Nr. 1 (Februar 1998): 15–20. http://dx.doi.org/10.3109/00048679809062701.

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Objective: We sought to identify the psychosocial characteristics of high earthquake exposure subjects that were associated with the development of post-disaster morbidity and with recovery. Method: Data reported are from 515 participants in a longitudinal study of the psychosocial effects of the 1989 Newcastle (Australia) earthquake. Subjects were allocated to three subgroups (low morbidity; recovered; and persistent morbidity) on the basis of their Impact of Event Scale scores across the four phases of the study. Differences between these subgroups were examined on a broad range of variables. Results: Several background, dispositional, coping style and exposure-related factors characterised those who developed psychological morbidity, only a small subset of which differentiated between those who recovered and those with persistent morbidity. Conclusions: Post-earthquake morbidity persists longer in those who are older, have a history of emotional problems, have higher neuroticism, use more neurotic defenses, and report higher levels of post-disaster life events.

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Russell, Stuart D., Kimberly L. Blackwell, Julia Lawrence, John E. Pippen, Matthew T. Roe, Freda Wood, Virginia Paton, Eric Holmgren und Kenneth W. Mahaffey. „Independent Adjudication of Symptomatic Heart Failure With the Use of Doxorubicin and Cyclophosphamide Followed by Trastuzumab Adjuvant Therapy: A Combined Review of Cardiac Data From the National Surgical Adjuvant Breast and Bowel Project B-31 and the North Central Cancer Treatment Group N9831 Clinical Trials“. Journal of Clinical Oncology 28, Nr. 21 (20.07.2010): 3416–21. http://dx.doi.org/10.1200/jco.2009.23.6950.

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Purpose An independent Adjuvant Cardiac Review and Evaluation Committee (ACREC) systematically reviewed cases of symptomatic heart failure events to uniformly define the cardiac event rate across two large trials (National Surgical Adjuvant Breast and Bowel Project [NSABP] B-31 and North Central Cancer Treatment Group [NCCTG] N9831) that assessed the addition of trastuzumab to standard adjuvant chemotherapy. Patients and Methods The committee was composed of six independent oncologists and cardiologists. A retrospective review of patients with a cardiac event was performed by the primary investigators of the trials. The ACREC prospectively established criteria for determining a symptomatic heart failure event. Recovery status was determined from documented resolution of signs and symptoms. Potential risk factors were also assessed. Results Medical records for a total of 173 patients were reviewed: 40 in the chemotherapy-alone arm and 133 in the trastuzumab arm. Trastuzumab-treated patients had a 2.0% incidence of symptomatic heart failure events compared with 0.45% in the chemotherapy-alone arm. Complete or partial recovery was observed in 86.1% of trastuzumab-treated patients with symptomatic heart failure events. Of five patients who died, only one patient had received trastuzumab. Independent predictors for cardiac events were age older than 50 years, a low ejection fraction at the start of paclitaxel treatment, and trastuzumab treatment. Conclusion The incidence of symptomatic heart failure events is 2.0% in patients treated with adjuvant trastuzumab, and the majority of these patients recover with appropriate treatment.

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Wyczalkowski, Christopher K., Eric J. van Holm, Ann–Margaret Esnard und Betty S. Lai. „Uneven Neighborhood Recovery: Hurricane Damage and Neighborhood Change in the Houston–Galveston Region since 1970“. City & Community 18, Nr. 2 (Juni 2019): 689–709. http://dx.doi.org/10.1111/cico.12390.

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Despite the growing number of natural disasters around the globe, limited research exists on post–disaster patterns of neighborhood change. In this paper, we test two theories of neighborhood change, the “recovery machine” and “rent gap,” which predict opposing effects for low socioeconomic status (SES) neighborhoods following damage from hurricanes, tropical storms, and other natural hazard events. The recovery machine theory posits that after natural hazard events, local communities experience patterns of recovery based on their pre–disaster SES and access to resources, suggesting that wealthier neighborhoods will recover robustly while lower status neighborhoods languish. In contrast, the rent gap theory suggests that developers will identify a profit opportunity in the depressed values created by damage from natural hazard events, and seek to redevelop low SES areas. We use fixed effects models with census data from 1970 to 2015 to test the impact of damage from natural hazards on neighborhood change. We find substantial recovery and change in low–income neighborhoods, but not in the high–income neighborhoods supporting the rent gap theory. We conclude that natural hazard events resulting in damage produce uneven recovery by socioeconomic status of neighborhoods, potentially leading to displacement of low SES groups.

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Brown, G. W., L. Lemyre und A. Bifulco. „Social Factors and Recovery from Anxiety and Depressive Disorders“. British Journal of Psychiatry 161, Nr. 1 (Juli 1992): 44–54. http://dx.doi.org/10.1192/bjp.161.1.44.

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Analysis of 33 instances of recovery or improvement among 92 women with anxiety, and 49 instances of recovery and improvement among 67 episodes of depression, showed that recovery and improvement, when compared with conditions not changing, were associated with a prior positive event. Such events were characterised by one or more of three dimensions: the ‘anchoring’ dimension involved increased security; ‘fresh-start’, increased hope arising from a lessening of a difficulty or deprivation; and ‘relief’, the amelioration of a difficulty not involving any sense of a fresh start. Events characterised by anchoring were more often associated with recovery or improvement in anxiety, and those characterised as fresh-start were associated with recovery or improvement in depression. Recovery or improvement in both disorders was more likely to be associated with both anchoring and fresh-start events. The study involved the reworking of some social and clinical material, and although done blind should be seen as exploratory.

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Cox, Zachary L., Allison B. McCoy, Michael E. Matheny, Gautam Bhave, Neeraja B. Peterson, Edward D. Siew, Julia Lewis et al. „Adverse Drug Events during AKI and Its Recovery“. Clinical Journal of the American Society of Nephrology 8, Nr. 7 (28.03.2013): 1070–78. http://dx.doi.org/10.2215/cjn.11921112.

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Lipps, Jere H. „Ecological Comebacks: Biotic Recovery from Mass Extinction Events.“ Science 274, Nr. 5289 (08.11.1996): 936.1–936. http://dx.doi.org/10.1126/science.274.5289.936.

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Lipps, J. H. „Ecological Comebacks: Biotic Recovery from Mass Extinction Events.“ Science 274, Nr. 5289 (08.11.1996): 936a. http://dx.doi.org/10.1126/science.274.5289.936a.

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Gomez, J. C., und M. M. Morcos. „Voltage Sag and Recovery Time in Repetitive Events“. IEEE Power Engineering Review 22, Nr. 7 (Juli 2002): 62. http://dx.doi.org/10.1109/mper.2002.4312427.

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Gomez, J. C., und M. M. Morcos. „Voltage sag and recovery time in repetitive events“. IEEE Transactions on Power Delivery 17, Nr. 4 (Oktober 2002): 1037–43. http://dx.doi.org/10.1109/tpwrd.2002.803840.

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Maraldo, Kristine, und Martin Holmstrup. „Recovery of enchytraeid populations after severe drought events“. Applied Soil Ecology 42, Nr. 3 (Juli 2009): 227–35. http://dx.doi.org/10.1016/j.apsoil.2009.04.004.

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Plodinec, M. John. „Stress Testing to Assess Recovery from Extreme Events“. Journal of Homeland Security and Emergency Management 18, Nr. 2 (11.03.2021): 151–76. http://dx.doi.org/10.1515/jhsem-2020-0012.

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Abstract Over the last decade, communities have become increasingly aware of the risks they face. They are threatened by natural disasters, which may be exacerbated by climate change and the movement of land masses. Growing globalization has made a pandemic due to the rapid spread of highly infectious diseases ever more likely. Societal discord breeds its own threats, not the least of which is the spread of radical ideologies giving rise to terrorism. The accelerating rate of technological change has bred its own social and economic risks. This widening spectrum of risk poses a difficult question to every community – how resilient will the community be to the extreme events it faces. In this paper, we present a new approach to answering that question. It is based on the stress testing of financial institutions required by regulators in the United States and elsewhere. It generalizes stress testing by expanding the concept of “capital” beyond finance to include the other “capitals” (e.g., human, social) possessed by a community. Through use of this approach, communities can determine which investments of its capitals are most likely to improve its resilience. We provide an example of using the approach, and discuss its potential benefits.

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Jahanian, Omid, Meegan G. Van Straaten, Brianna M. Goodwin, Stephen M. Cain, Ryan J. Lennon, Jonathan D. Barlow, Naveen S. Murthy und Melissa M. B. Morrow. „Inertial Measurement Unit–Derived Ergonomic Metrics for Assessing Arm Use in Manual Wheelchair Users With Spinal Cord Injury: A Preliminary Report“. Topics in Spinal Cord Injury Rehabilitation 27, Nr. 3 (13.08.2021): 12–25. http://dx.doi.org/10.46292/sci20-00059.

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Background: Individuals with spinal cord injury (SCI) who use manual wheelchairs (MWCs) have a higher rate of rotator cuff pathology progression than able-bodied individuals. Objectives: This study aimed to test the ability of risk and recovery metrics of arm use to differentiate between (1) MWC users with SCI and matched able-bodied participants (cross-sectional matched-sample study) and (2) MWC users with rotator cuff pathology progression over 1 year from those without pathology progression (longitudinal study). Methods: Thirty-four MWC users and 34 age- and sex-matched able-bodied individuals were recruited. Upper arm risk (humeral elevation >60°) and recovery (static ≥5 seconds and humeral elevation <40°) metrics were calculated from wireless inertial measurement units (IMUs) worn on the upper arms and torso in the free-living environment. Two separate magnetic resonance imaging studies were completed and assessed for a subset of 16 MWC users approximately 1 year apart. Results: The frequency of risk events (p = .019), summated duration of recovery events (p = .025), and duration of each recovery event (p = .003) were higher for MWC users than able-bodied participants. The summated duration of risk events (p = .047), frequency of risk events (p = .027), and risk to recovery ratio (p = .02) were higher and the summated duration of recovery events (p = .036) and frequency of recovery events (p = .047) were lower for MWC users with rotator cuff pathology progression (n = 5) compared to those without progression (n = 11). Conclusion: IMU-derived metrics quantifying arm use at postures >60° and risk to recovery ratios may provide insights of potential risk factors for rotator cuff pathology progression.

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Rodríguez-Tovar, Francisco J., Christopher M. Lowery, Timothy J. Bralower, Sean P. S. Gulick und Heather L. Jones. „Rapid macrobenthic diversification and stabilization after the end-Cretaceous mass extinction event“. Geology 48, Nr. 11 (13.07.2020): 1048–52. http://dx.doi.org/10.1130/g47589.1.

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Abstract Previous ichnological analysis at the Chicxulub impact crater, Yucatán Peninsula, México (International Ocean Discovery Program [IODP]/International Continental Scientific Drilling Program [ICDP] Site M0077), showed a surprisingly rapid initial tracemaker community recovery after the end-Cretaceous (Cretaceous-Paleogene [K-Pg]) mass extinction event. Here, we found that full recovery was also rapid, with the establishment of a well-developed tiered community within ∼700 k.y. Several stages of recovery were observed, with distinct phases of stabilization and diversification, ending in the development of a trace fossil assemblage mainly consisting of abundant Zoophycos, Chondrites, and Planolites, assigned to the Zoophycos ichnofacies. The increase in diversity is associated with higher abundance, larger forms, and a deeper and more complex tiering structure. Such rapid recovery suggests that favorable paleoenvironmental conditions were quickly reestablished within the impact basin, enabling colonization of the substrate. Comparison with the end-Permian extinction reveals similarities during recovery, yet postextinction recovery was significantly faster after the K-Pg event. The rapid recovery has significant implications for the evolution of macrobenthic biota after the K-Pg event. Our results have relevance in understanding how communities recovered after the K-Pg impact and how this event differed from other mass extinction events.

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Schoepf, Verena, Andréa G. Grottoli, Stephen J. Levas, Matthew D. Aschaffenburg, Justin H. Baumann, Yohei Matsui und Mark E. Warner. „Annual coral bleaching and the long-term recovery capacity of coral“. Proceedings of the Royal Society B: Biological Sciences 282, Nr. 1819 (22.11.2015): 20151887. http://dx.doi.org/10.1098/rspb.2015.1887.

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Mass bleaching events are predicted to occur annually later this century. Nevertheless, it remains unknown whether corals will be able to recover between annual bleaching events. Using a combined tank and field experiment, we simulated annual bleaching by exposing three Caribbean coral species ( Porites divaricata , Porites astreoides and Orbicella faveolata ) to elevated temperatures for 2.5 weeks in 2 consecutive years. The impact of annual bleaching stress on chlorophyll a , energy reserves, calcification, and tissue C and N isotopes was assessed immediately after the second bleaching and after both short- and long-term recovery on the reef (1.5 and 11 months, respectively). While P. divaricata and O. faveolata were able to recover from repeat bleaching within 1 year, P. astreoides experienced cumulative damage that prevented full recovery within this time frame, suggesting that repeat bleaching had diminished its recovery capacity. Specifically, P. astreoides was not able to recover protein and carbohydrate concentrations. As energy reserves promote bleaching resistance, failure to recover from annual bleaching within 1 year will likely result in the future demise of heat-sensitive coral species.

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Masasuke Takashima* und Haruo Hayashi**. „Monitoring Recovery Using Energy Consumption Indices“. Journal of Disaster Research 2, Nr. 6 (01.12.2007): 445–52. http://dx.doi.org/10.20965/jdr.2007.p0445.

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A methodology to monitor the socio-economic impact due to a catastrophic event in high spatial resolution, high frequency, and in homogenous manner within the entire affected area is indispensable to maintain an up-to-date overall picture of the event in disaster response/recovery operations. Energy consumption of the affected area is a promising index for long-term recovery monitoring. The energy consumption of an urbanized area strongly correlates with its socioeconomic activity. When an area is urbanized and developed, more energy is required to maintain it. Once a catastrophic event interrupts these activities, energy consumption of the area decreases. We have been studying ways to monitor long-term recovery using electric power supply data and the night time city light imagery data provided by the Defense Meteorological Satellite Program as indices of energy consumption. In this paper, we introduce these methodologies and their application to recovery process monitoring after the Kobe earthquake in Japan and Hurricane Katrina in the U.S. The impact and following recovery process of those two catastrophic events were clearly depicted. These examples have shown both methodologies to be promising in monitoring the spaciotemporal distribution of impact due to events independent of the type of hazard. Recovery monitoring methodologies introduced in this paper provide a way to determine overall trends in recovery of affected areas macroscopically. For concrete policy making and support, a more detailed view is also needed to evaluate recovery conditions of different social and economic sectors and individual households and businesses. Both macroscopic and microscopic viewpoints are needed to appropriate response and recovery operations.

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THOMPSON FULLILOVE, MINDY, LOURDES HERNANDEZ-CORDERO, JENNIFER STEVENS MADOFF und ROBERT E. FULLILOVE III. „PROMOTING COLLECTIVE RECOVERY THROUGH ORGANIZATIONAL MOBILIZATION: THE POST-9/11 DISASTER RELIEF WORK OF NYC RECOVERS“. Journal of Biosocial Science 36, Nr. 4 (23.06.2004): 479–89. http://dx.doi.org/10.1017/s0021932004006741.

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NYC RECOVERS, an alliance of organizations concerned with New York City’s social and emotional recovery post-9/11, was formed to meet the need to rebuild social bonds strained or ruptured by the trauma to the regional system caused by the destruction of the Twin Towers. NYC RECOVERS, with minimal funding, was able to create a network of 1000 organizations spanning the five boroughs, carrying out recovery events throughout the ‘Year of Recovery’, September 2001 to December 2002. This paper describes the concepts, techniques and accomplishments of NYC RECOVERS, and discusses potentials of the model, as well as obstacles to its implementation.

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Shin, Michael E. „Socio-Geographic Dimensions of Recovery from the 2002 Molise, Italy, Earthquake“. Earthquake Spectra 20, Nr. 1_suppl (Juli 2004): 315–21. http://dx.doi.org/10.1193/1.1767522.

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Several factors influence the abilities of communities to cope with, respond to, and recover from earthquakes. Beyond the uncontrollable geophysical factors (e.g., the magnitude and type of earthquake) are the complex array of historic, social, economic, political, and cultural forces that affect loss reduction, response, and recovery. This paper uses a geographic perspective to situate the communities most affected by the 2002 Molise, Italy, event. This area of Italy is characterized by economic underdevelopment, an aging population, and out-migration. The earthquake effects may exacerbate these preexisting conditions. In order to obtain reliable and accurate insights into the recovery process, better socio-economic data and information must be gathered following seismic events. Such data are essential to understanding the process and dimensions of recovery in Molise and in other locations.

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Lonial, Sagar, Ajay Nooka, Praneetha Thulasi, Ashraf Z. Badros, Bennie H. Jeng, Natalie S. Callander, Douglas Sborov et al. „Recovery of Ocular Events with Longer-Term Follow-up in the DREAMMM-2 Study of Single-Agent Belantamab Mafodotin (Belamaf) in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)“. Blood 136, Supplement 1 (05.11.2020): 26–27. http://dx.doi.org/10.1182/blood-2020-140078.

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Introduction: Patients with heavily pretreated RRMM have a poor prognosis (median overall survival [OS]: 6-9 months) and a need for novel, well-tolerated treatments that induce lasting responses (Gandhi Leukemia 2019; Chari NEJM 2019). Belamaf (GSK2857916) is a first-in-class, B-cell maturation antigen-targeting, antibody-drug conjugate (ADC) containing monomethyl auristatin F (MMAF). In DREAMM-2 (NCT03525678), patients with heavily pretreated RRMM who responded to single-agent belamaf maintained deep and durable responses at 13-month follow-up (median OS: >13 months) with a manageable safety profile (Lonial ASCO 2020, Poster 436). Consistent with other MMAF-containing ADCs, ocular events were common (Farooq et al. Ophthal Ther 2020). These events included keratopathy (microcyst-like epithelial changes [MECs]: an eye exam finding with/without symptoms), best-corrected visual acuity (BCVA) changes, and symptoms (blurred vision and dry eye). Longer-term recovery data will help inform management strategies. Methods: In DREAMM-2, eye exams were conducted at baseline and prior to each dose in patients received single-agent belamaf (2.5 or 3.4 mg/kg Q3W) and included a corneal exam and assessment of BCVA change from baseline (Snellen visual acuity [VA]). Dose modifications (delays/reductions) were permitted to manage these events. The corneal events were graded per the Keratopathy and Visual Acuity (KVA) scale, which combined corneal exam findings and BCVA changes from baseline. Dose modifications were determined based on the most severe KVA scale grade. These events were followed until recovery, defined as any Grade 1 exam findings/no exam findings, and ≤1-line decline in Snellen VA compared with baseline. A change to a BCVA 20/50 or worse (ie, limiting driving ability) in the better-seeing eye (in patients with BCVA better than 20/50 at baseline) was considered one definition of clinically meaningful VA decrease. Recovery of these events was defined as BCVA improvement to better than 20/50 (better-seeing eye). We report ocular event outcomes for patients receiving belamaf 2.5 mg/kg (recommended dose for future clinical development) from a 13-month follow-up post-hoc analysis. Results: In patients receiving single-agent belamaf 2.5 mg/kg, 72% (68/95) experienced a treatment-related eye exam finding of keratopathy (MECs) (Farooq Ophthal Ther 2020).Fewer patients (56%; 53/95) had symptoms (eg, blurred vision or dry eye) and/or a ≥2-line BCVA decline (better-seeing eye). Treatment discontinuations due to ocular events were rare (3% [3/95] total; 1% [1/95] each due to keratopathy [MECs], blurred vision, and reduced BCVA (Farooq Ophthal Ther 2020). In patients with keratopathy (MEC) events Grade ≥2 per KVA, 48% (29/60) had >1 event. The first event recovered in 77% (46/60; Table; Farooq Ophthal Ther 2020). At last follow-up, 48% (29/60) had documented recovery of their most recent event (Farooq Ophthal Ther 2020). In patients with unrecovered events at last follow-up, 45% (14/31) are receiving treatment or in follow-up. The remaining 55% (17/31) are no longer in follow-up (9 died; 4 withdrew from study; 4 lost to follow-up). 84% (37/44) of patients with Grade 3/4 events were improving or had recovered events at last follow-up. Seventeen (18%) patients had a clinically meaningful BCVA decline, with no reports of complete permanent vision loss (Farooq Ophthal Ther 2020). Of these patients, 76% (13/17) had 1 event and 24% (4/17) had 2 events (no patients had >2 events). 82% (14/17) had recovery of their first event and 82% (14/17) had recovery at last follow-up (Farooq Ophthal Ther 2020). Of the remaining 3 patients with unrecovered events, 1 patient is receiving treatment and 2 patients are no longer in follow-up (1 died due to disease progression; 1 withdrew from study). Conclusions: Though keratopathy (MECs) were frequently observed on eye exam, the majority of patients did not experience a clinically meaningful BCVA decline, and events rarely led to treatment discontinuation. The first keratopathy (MEC) event or clinically meaningful BCVA decline recovered in the majority of patients with events. In this ongoing study, patients are being followed for recovery. Based on experience, it is anticipated these events will likely recover over time. Funding: GSK (205678); drug linker technology licensed from Seattle Genetics; mAb produced using POTELLIGENT Technology licensed from BioWa. Disclosures Lonial: Karyopharm: Consultancy; Sanofi: Consultancy; Amgen: Consultancy, Honoraria, Other: Personal fees; Onyx: Honoraria; Takeda: Consultancy, Other: Personal fees, Research Funding; Novartis: Consultancy, Honoraria, Other: Personal fees; Janssen: Consultancy, Honoraria, Other: Personal fees, Research Funding; BMS: Consultancy, Honoraria, Other: Personal fees, Research Funding; GSK: Consultancy, Honoraria, Other: Personal fees; Abbvie: Consultancy; Merck: Consultancy, Honoraria, Other: Personal fees; JUNO Therapeutics: Consultancy; TG Therapeutics: Membership on an entity's Board of Directors or advisory committees; Millennium: Consultancy, Honoraria; Genentech: Consultancy. Nooka:Spectrum Pharmaceuticals: Consultancy; Oncopeptides: Consultancy, Honoraria; Adaptive Technologies: Consultancy, Honoraria; GlaxoSmithKline: Consultancy, Honoraria, Other: Personal Fees: Travel/accomodations/expenses, Research Funding; Takeda: Consultancy, Honoraria, Research Funding; Sanofi: Consultancy, Honoraria; Celgene: Consultancy, Honoraria, Research Funding; Karyopharm Therapeutics, Adaptive technologies: Consultancy, Honoraria, Research Funding; Janssen: Consultancy, Honoraria, Research Funding; Amgen: Consultancy, Honoraria, Research Funding; Bristol-Myers Squibb: Consultancy, Honoraria, Research Funding. Thulasi:Emory University: Current Employment. Badros:University of Maryland: Current Employment; Amgen: Consultancy. Jeng:Kedrion, Merck, GSK: Consultancy; University of Maryland: Current Employment; EyeGate: Current equity holder in publicly-traded company. Callander:University of Wisconsin: Current Employment; Cellectar: Research Funding. Sborov:University of Utah: Current Employment; Celgene, Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Other: Personal fees. Zaugg:University of Utah: Current Employment. Popat:Celgene: Consultancy, Honoraria; Bristol Myers Squibb: Consultancy, Honoraria; Takeda: Consultancy, Honoraria, Other: Travel support, Research Funding; Janssen: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company); GSK: Consultancy, Honoraria, Other: TRAVEL, ACCOMMODATIONS, EXPENSES (paid by any for-profit health care company); AbbVie: Consultancy, Honoraria. Degli Esposti:GlaxoSmithKline: Consultancy, Honoraria; Moorfields Eye Hospital: Current Employment. Byrne:Adaptimmune, Novartis: Current equity holder in publicly-traded company; GlaxoSmithKline: Current Employment, Current equity holder in publicly-traded company. Opalinska:GlaxoSmithKline: Current Employment, Current equity holder in publicly-traded company. Baron:GlaxoSmithKline: Current Employment, Current equity holder in publicly-traded company. Piontek:GlaxoSmithKline: Current Employment, Current equity holder in publicly-traded company. Gupta:Novartis: Current equity holder in publicly-traded company; GlaxoSmithKline: Current Employment, Current equity holder in publicly-traded company. Dana:Kala: Consultancy; Alcon: Consultancy; GSK: Consultancy; Aramis Biosciences, Claris Biotherapeutics, GelMEDIX: Current equity holder in private company; Novartis: Consultancy; Dompe: Consultancy; Massachusetts Eye and Ear; Harvard Medical School Department of Ophthalmology: Current Employment; NIH, DOD, Allegan: Current equity holder in publicly-traded company. Farooq:GlaxoSmithKline: Consultancy; University of Chicago: Current Employment. Jakubowiak:Adaptive, Juno: Consultancy, Honoraria; AbbVie, Amgen, BMS/Celgene, GSK, Janssen, Karyopharm: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees.

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Holt, Carrie A. „Will depleted populations of Pacific salmon recover under persistent reductions in survival and catastrophic mortality events?“ ICES Journal of Marine Science 67, Nr. 9 (09.09.2010): 2018–26. http://dx.doi.org/10.1093/icesjms/fsq117.

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Abstract Holt, C. A. 2010. Will depleted populations of Pacific salmon recover under persistent reductions in survival and catastrophic mortality events? – ICES Journal of Marine Science, 67: 2018–2026. Under Canada's Wild Salmon Policy, benchmarks between zones of biological status are required to distinguish populations requiring conservation attention (Red and Amber zones) from those that can be managed for production (Green zone). The recovery of depleted populations (i.e. from Red to Green) will depend in part on the choice of the lower benchmark. At a minimum, that benchmark should be set high enough to allow recovery within an acceptable time-frame in the absence of targeted fishing. Currently, benchmarks are evaluated and selected using simulation models that assess the probability of recovery to spawner abundance associated with the maximum sustainable yield within a specified time-frame. Guided by case examples, the evaluation is extended to include two scenarios of future conditions: persistent reductions in survival rates below the replacement level; and increased frequency of catastrophic mortality (die-off) events. Probabilities of recovery appear to be more sensitive to persistent reductions in survival than to increased probability of die-off events. The current lower benchmarks on spawner abundance and fishing mortality might not be sufficiently precautionary to allow recovery under those conditions.

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Tucker, Jalie A., Rudy E. Vuchinich und Julie Akiko Gladsjo. „Environmental Events Surrounding Natural Recovery from Alcohol-Related Problems“. Journal of Addictions Nursing 6, Nr. 4 (1994): 117–28. http://dx.doi.org/10.3109/10884609409021737.

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Kohler, Tyler J., Ethan Chatfield, Michael N. Gooseff, John E. Barrett und Diane M. McKnight. „Recovery of Antarctic stream epilithon from simulated scouring events“. Antarctic Science 27, Nr. 4 (17.03.2015): 341–54. http://dx.doi.org/10.1017/s0954102015000024.

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AbstractMicrobial mats are common in polar streams and often dominate benthic biomass. Climate change may be enhancing the variability of stream flows in the Antarctic, but so far studies investigating mat responses to disturbance have been limited in this region. Mat regrowth was evaluated following disturbance by experimentally scouring rocks from an ephemeral McMurdo Dry Valley stream over two summers (2001–02 and 2012–13). Mats were sampled at the beginning and resampled at the end of the flow season. In 2012–13, mats were additionally resampled mid-season along with previously undisturbed controls. In 2001–02 rocks regained 47% of chlorophyll a and 40% of ash-free dry mass by the end of the summer, while in 2012–13 rocks regrew 18% and 27%, respectively. Mat stoichiometry differed between summers, and reflected differences in biomass and discharge. Oscillatoria spp. were greatest on scoured rocks and Phormidium spp. on undisturbed rocks. Small diatoms Humidophila and Fistulifera spp. increased throughout the summer in all mats, with the latter more abundant in scoured communities. Collectively, these data suggest that mats are variable intra-annually, responsive to hydrology and require multiple summers to regrow initial biomass once lost. These results will aid the interpretation of long-term data, as well as inform Antarctic Specially Managed Area protocols.

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Bravo, Jorge M. V., und Richard Chamboko. „Modelling and forecasting recurrent recovery events on consumer loans“. International Journal of Applied Decision Sciences 12, Nr. 1 (2019): 1. http://dx.doi.org/10.1504/ijads.2019.10019811.

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Chamboko, Richard, und Jorge M. V. Bravo. „Modelling and forecasting recurrent recovery events on consumer loans“. International Journal of Applied Decision Sciences 12, Nr. 3 (2019): 271. http://dx.doi.org/10.1504/ijads.2019.100440.

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Macdonald, John R., und Thomas M. Corsi. „Supply Chain Disruption Management: Severe Events, Recovery, and Performance“. Journal of Business Logistics 34, Nr. 4 (Dezember 2013): 270–88. http://dx.doi.org/10.1111/jbl.12026.

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Tucker, J. A., R. E. Vuchinich und J. A. Gladsjo. „Environmental events surrounding natural recovery from alcohol-related problems.“ Journal of Studies on Alcohol 55, Nr. 4 (Juli 1994): 401–11. http://dx.doi.org/10.15288/jsa.1994.55.401.

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Larsen, Sadie E., und Howard Berenbaum. „Substantial Symptom Changes in Naturalistic Recovery from Aversive Events“. Journal of Clinical Psychology 70, Nr. 10 (09.04.2014): 967–78. http://dx.doi.org/10.1002/jclp.22092.

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Hu, Yue, und Daniel B. Work. „Robust Tensor Recovery with Fiber Outliers for Traffic Events“. ACM Transactions on Knowledge Discovery from Data 15, Nr. 1 (06.01.2021): 1–27. http://dx.doi.org/10.1145/3417337.

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Selsted, Merete Bang, K. Albert, P. Ambus, A. Michelsen, H. Ro-Poulsen, T. Mikkelsen und A. Ibrom. „Ecosystem recovery after drought events in our future climate“. IOP Conference Series: Earth and Environmental Science 6, Nr. 4 (01.01.2009): 042029. http://dx.doi.org/10.1088/1755-1307/6/4/042029.

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Chen, Yuting, Ping Lou und Wen Jiang. „Enhanced Variable Neighborhood Search-Based Recovery Supplier Selection for Post-Disruption Supply Networks“. Processes 9, Nr. 4 (11.04.2021): 670. http://dx.doi.org/10.3390/pr9040670.

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With the increasing reliance on global sourcing and the growth in the likelihood of disruptive incidents, today’s supply networks are more prone to unexpected natural and man-made disruptive events. In order to alleviate the losses caused by these disruptive events, when a large-scale event disrupts multiple suppliers simultaneously, a single or several critical suppliers should be selected from the disrupted ones to assist them to recover their production as soon as possible. The selection of these recovery suppliers is of great importance in the recovery process of the entire supply network. Thus, this paper proposes a recovery supplier selection method from the view of the supply network structure. Firstly, a tripartite graph-based supply model is proposed to depict a two-stage supply network, which consists of multiple manufacturers and suppliers as well as the diverse product supply-demand interdependence connecting them. To measure the impacts caused by supplier disruptions and to evaluate the effectiveness of recovery supplier decisions, two supply network performance metrics reflecting product supply availability are also given. Then, the recovery supplier selection problem is described as a combinatorial optimization problem. To solve this problem, a heuristic algorithm, with enhanced variable neighborhood search (EVNS) is designed based on the general framework of a variable neighborhood search. Finally, experiments based on a real-world supply network are conducted. The experimental results indicate that the proposed method is applicable and effective.

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Carra, Kylie, Nerida Hyett, Amanda Kenny und Michael Curtin. „Strengthening occupational therapy practice with communities after traumatic events“. British Journal of Occupational Therapy 82, Nr. 5 (27.08.2018): 316–19. http://dx.doi.org/10.1177/0308022618795594.

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Occupational therapists have immense potential to strengthen their role in supporting communities to recover from collective trauma. After traumatic events, a community-centred practice approach can be used by occupational therapists to improve health, safety, security and wellbeing at a population level. Three strategies to strengthen the role of occupational therapy in this critical area of practice are proposed: (a) work collaboratively with communities to design programmes centred on community strengths and needs; (b) select and use therapeutic occupations to support community recovery; and (c) develop strong networks to enhance community partnerships and sustainability of services.

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Kaderli, Jordan, Matthew D. McChesney und Susan E. Minkoff. „A self-adjoint velocity-stress full-waveform inversion approach to microseismic source estimation“. GEOPHYSICS 83, Nr. 5 (01.09.2018): R413—R427. http://dx.doi.org/10.1190/geo2017-0557.1.

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Accurate estimation of microseismic events in time and space enables important characterization of hydraulic fracture networks. Determining the orientation of the fracture can help differentiate between reactivation of an in situ fracture and a hydraulically induced fracture, which is important in characterizing the effectiveness of the stimulation process. We consider the source as separable in time and space and invert for a complete description of the source in one of these two dimensions assuming the other is known. We recover the wavelet, which includes the source amplitude and time evolution. In space, we recover a description of the source that is distributed and includes an estimate of the moment tensor at every point in the domain. A change of variables applied to the velocity-stress form of the elastic-wave equation ensures that the system is self-adjoint. Thus, full-waveform inversion can be tailored to estimate microseismic events with limited modifications to the forward wave solver. The inversion does not use any a priori assumptions about the form of the source, does not require a good starting guess for accurate source recovery, and is robust in the presence of noise. Applying this technique to wavelet inversion correctly recovers a 30 Hz Ricker wavelet from a zero initial guess with and without noise. Furthermore, for a realistic microseismic event generated from coupled flow and deformation modeling, the algorithm recovers the peak time and approximate shape of the wavelet. In fact, our algorithm recovers as much of the true wavelet as possible given the energy in the observed data. Furthermore, experiments involving a distributed source in the shape of an ellipse illustrate that the inversion scheme can not only estimate the focal mechanism of failure events, but also the geometry of the failure plane.

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De Faria, Bruno L., Gina Marano, Camille Piponiot, Carlos A. Silva, Vinícius de L. Dantas, Ludmila Rattis, Andre R. Rech und Alessio Collalti. „Model-Based Estimation of Amazonian Forests Recovery Time after Drought and Fire Events“. Forests 12, Nr. 1 (23.12.2020): 8. http://dx.doi.org/10.3390/f12010008.

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In recent decades, droughts, deforestation and wildfires have become recurring phenomena that have heavily affected both human activities and natural ecosystems in Amazonia. The time needed for an ecosystem to recover from carbon losses is a crucial metric to evaluate disturbance impacts on forests. However, little is known about the impacts of these disturbances, alone and synergistically, on forest recovery time and the resulting spatiotemporal patterns at the regional scale. In this study, we combined the 3-PG forest growth model, remote sensing and field derived equations, to map the Amazonia-wide (3 km of spatial resolution) impact and recovery time of aboveground biomass (AGB) after drought, fire and a combination of logging and fire. Our results indicate that AGB decreases by 4%, 19% and 46% in forests affected by drought, fire and logging + fire, respectively, with an average AGB recovery time of 27 years for drought, 44 years for burned and 63 years for logged + burned areas and with maximum values reaching 184 years in areas of high fire intensity. Our findings provide two major insights in the spatial and temporal patterns of drought and wildfire in the Amazon: (1) the recovery time of the forests takes longer in the southeastern part of the basin, and, (2) as droughts and wildfires become more frequent—since the intervals between the disturbances are getting shorter than the rate of forest regeneration—the long lasting damage they cause potentially results in a permanent and increasing carbon losses from these fragile ecosystems.

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González, Victoria T., Bente Lindgård, Rigmor Reiersen, Snorre B. Hagen und Kari Anne Bråthen. „Niche construction mediates climate effects on recovery of tundra heathlands after extreme event“. PLOS ONE 16, Nr. 2 (04.02.2021): e0245929. http://dx.doi.org/10.1371/journal.pone.0245929.

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Climate change is expected to increase the frequency and intensity of extreme events in northern ecosystems. The outcome of these events across the landscape, might be mediated by species effects, such as niche construction, with likely consequences on vegetation resilience. To test this hypothesis, we simulated an extreme event by removing aboveground vegetation in tundra heathlands dominated by the allelopathic dwarf shrub Empetrum nigrum, a strong niche constructor. We tested the hypothesis under different climate regimes along a 200-km long gradient from oceanic to continental climate in Northern Norway. We studied the vegetation recovery process over ten years along the climatic gradient. The recovery of E. nigrum and subordinate species was low and flattened out after five years at all locations along the climatic gradient, causing low vegetation cover at the end of the study in extreme event plots. Natural seed recruitment was low at all sites, however, the addition of seeds from faster growing species did not promote vegetation recovery. A soil bioassay from 8 years after the vegetation was removed, suggested the allelopathic effect of E. nigrum was still present in the soil environment. Our results provide evidence of how a common niche constructor species can dramatically affect ecosystem recovery along a climatic gradient after extreme events in habitats where it is dominant. By its extremely slow regrowth and it preventing establishment of faster growing species, this study increases our knowledge on the possible outcomes when extreme events harm niche constructors in the tundra.

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Cottini, Francesca, Nita Williams, Naresh Bumma, Abdullah Mohammad Khan, Maria Chaudhry, Srinivas S. Devarakonda, Yvonne Adeduni Efebera, Don M. Benson und Ashley Elizabeth Rosko. „Daratumumab-induced lymphopenia predicts adverse events and outcomes in patients with myeloma.“ Journal of Clinical Oncology 38, Nr. 15_suppl (20.05.2020): e20534-e20534. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e20534.

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e20534 Background: Daratumumab, a monoclonal antibody against CD38, is very effective in patients with Multiple Myeloma (MM). CD38 is expressed on MM cells but also on normal lymphocytes. Therapy-induced lymphopenia has been reported in 30-40% of patients; however its clinical significance is vastly unexplored. Methods: Here, we report the baseline characteristics and clinical course of 100 relapsed/refractory MM patients treated at the Ohio State University with Daratumumab as single agent or in combination. Data pertaining to patient demographics, MM characteristics, absolute lymphocyte count-ALC, infections, and hospital stays were collected. ALC of less or equal to 500 cells/µL is considered severe lymphopenia. Results: Fifty-nine percent of patients who completed treatment with Daratumumab (59%) developed severe lymphopenia. MM type (LLC and IgA), combination with immunomodulatory drugs (IMIDs), and lower baseline ALC count were statistically associated with severe lymphopenia, while stage, age, cytogenetics, number of prior lines of treatment, and autologous stem cell transplant were not. Patients with severe lymphopenia had higher rates of infections (52.5% versus 41.4%) and required hospital stays more frequently (83.8% versus 52.9%) than patients without severe lymphopenia. Upper respiratory tract infections and pneumonias were the most common infections. Sixty-one percent of severely lymphopenic patients recovered to ALC > 500 lymphocyte/μL while on therapy. The median time to recover was 14 days (average 43 days). Older patients have longer ALC recovery time (average: 52 days versus 24 days). No statistically significant difference in progression-free survival (PFS), overall survival (OS), or overall response rate (ORR) was noted between patients who did or did not develop severe lymphopenia. However, when the severe lymphopenic group was stratified based on ALC recovery, those with persistent lymphopenia had worst OS (p = 0.0019) and PFS (p < 0.0001), possibly due to better immune-mediated anti-tumoral effects. Conclusions: In our patient population, we discovered an elevated rate of severe lymphopenia, hospital utilization, and infections. Persistent severe lymphopenia is associated with shorter PFS and worst OS. Combination with IMIDs and low baseline ALC count are risk factors for severe lymphopenia while patients older than 65 has a longer ALC recovery time. These findings underline the importance of monitoring lymphocyte count and considering prophylactic measures in high-risk patients treated with Daratumumab.

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Sanchis, Raquel, Luca Canetta und Raúl Poler. „A Conceptual Reference Framework for Enterprise Resilience Enhancement“. Sustainability 12, Nr. 4 (16.02.2020): 1464. http://dx.doi.org/10.3390/su12041464.

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Enterprise resilience is a key capacity to guarantee enterprises’ long-term continuity. This paper proposes the enterprise resilience Conceptual Reference Framework to characterize enterprise resilience capacity. The framework is composed of 71 disruptive events that enterprises consider as endangerments to their continuity. The framework also comprises constituent capabilities of enterprise resilience in terms of preparedness and recovery capabilities and elements that support the transition from the AS IS situation to the TO BE one, which are preventive actions (for preparedness capability) and knowledge registration actions (for recovery capability). From the preparedness perspective, 403 preventive actions are currently defined. Each preventive action is specific for every disruptive event. However, it is worth noting that a preventive action can also be applied to different disruptive events. From the recovery perspective, the proposed framework indicates knowledge registration related to (i) the occurrence of disruptive events; (ii) the recovery actions performed to re-establish the normal enterprise operation level. Further research lines are addressed to develop quantitative methods and tools to assess the extent of enterprises’ resilience following the foundations of the proposed conceptual framework.

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Stethen, Trent W., Yasir A. Ghazi, Robert Eric Heidel, Brian J. Daley, Linda Barnes, Donna Patterson und James M. McLoughlin. „Walking to recovery: the effects of missed ambulation events on postsurgical recovery after bowel resection“. Journal of Gastrointestinal Oncology 9, Nr. 5 (Oktober 2018): 953–61. http://dx.doi.org/10.21037/jgo.2017.11.05.

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North, Clive, Simon Gowers und Victoria Byram. „Family functioning and life events in the outcome of adolescent anorexia nervosa“. British Journal of Psychiatry 171, Nr. 6 (Dezember 1997): 545–49. http://dx.doi.org/10.1192/bjp.171.6.545.

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BackgroundThis study investigates the outcome of anorexia nervosa in adolescents in relation to precipitating life events and changes in family functioning over time.MethodThirty-five adolescents with anorexia nervosa and their mothers were administered measures of life events and family functioning at initial assessment and 1 and 2 year follow-up, when outcome was also assessed.ResultsFifty-five per cent of patients had a good outcome. Patients from initially well-functioning families or those with precipitating life events improved more in the first year, than those with dysfunctional families or without events. Subjects perceived a deterioration in family functioning at 1 year follow-up but an improvement at 2 years. Mothers reported no changes.ConclusionsApproximately half of a series of early onset cases of anorexia nervosa can be expected to recover by 2 years. Healthy family functioning and presence of a precipitating life event predict good short-term outcome. The relationships between subjects' perceptions of family functioning and their recovery from anorexia nervosa is discussed.

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