Thematische Bibliographien / RAGE method

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Auswahl der wissenschaftlichen Literatur zum Thema „RAGE method“

Autor: Grafiati
Veröffentlicht am 8. Februar 2025

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Zeitschriftenartikel zum Thema "RAGE method"

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Liu, Zixuan. „Research on Road Rage Detection System Based on Multi-feature Fusion“. International Journal of Computer Science and Information Technology 4, Nr. 2 (10.10.2024): 48–54. http://dx.doi.org/10.62051/ijcsit.v4n2.07.

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The influence of driver's rage on driving safety is one of the centers of traffic accident research. Road rage is a common potential factor affecting driving safety. Real-time monitoring of driver's emotional state and timely intervention measures can effectively reduce the incidence of traffic accidents. At present, the reliability of driver emotion recognition based on single consistent factor for road rage needs to be further improved. Therefore, based on the multi-feature fusion method, this paper proposes a recognition method of driver's road rage emotional state that integrates facial expression, driving control, voice text and physiological characteristics, and proposes the analysis of fusion strategy. In order to improve the reliability and implementability of road rage symptom judgment, this paper studies the state identification methods of road rage and integrates the characteristics of road rage. The focus of this study is to solve the key problem of insufficient reliability of road rage recognition based on facial expressions through the combination of multiple features and multiple data, aiming at the defects of the study on the single feature of road rage, and effectively improve the accuracy of road rage state emotion detection.
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Kumar, Varun, Alba Sulaj, Thomas Fleming und Peter Nawroth. „Purification and Characterization of the Soluble form of the Receptor for Advanced Glycation End-Products (sRAGE): A Novel Fast, Economical and Convenient Method“. Experimental and Clinical Endocrinology & Diabetes 126, Nr. 03 (19.09.2017): 141–47. http://dx.doi.org/10.1055/s-0043-110478.

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AbstractThe receptor for advanced glycation end-products (RAGE) is a multi-ligand receptor which belongs to the pattern recognition receptor family and can bind to various ligands such as advanced glycation end-products (AGEs), members of the S100 protein family, glycosaminoglycans, amyloid β peptides, high-mobility group box-1 (HMGB1) and nucleic acids through its extracellular domain. The RAGE-ligand interaction leads to the activation of MAP kinase and NF-kB signaling pathways. Further ligand-induced up-regulation of RAGE is involved in various patho-physiological situations including late diabetic complications, Alzheimer disease and several other neurodegenerative diseases. A secreted soluble isoform of RAGE (sRAGE), corresponding to the extracellular domain only, has the ability to block RAGE-associated cellular activation and signaling. Further application of recombinant sRAGE has been shown to block RAGE-mediated pathophysiological conditions in various models of cancer or multiple sclerosis. These finding demonstrates sRAGE as a therapeutic tool to block RAGE-associated inflammatory signaling. In this manuscript, we describe a two-step simple, novel and convenient method for expressing and purifying scalable quantities of biologically active murine form of sRAGE by using E.coli as an expression host. The method we propose has several advantages over the current available methods particularly in terms of yield and quality of preparation. The sRAGE produced by this expression system retains all the secondary structural properties as analyzed by the ligand binding affinities. The produced protein also retains all the DNA-RAGE binding functional properties and thus can be a valuable tool for studying dynamics of this novel RAGE ligand. Moreover this method can be utilized by researchers to generate biologically active endotoxin-free sRAGE for in vivo applications to study and treat RAGE-associated pathologies.
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Jones-Heiland, Teri. „RAGE: A Method for Rapid Gene Expression Profiling“. Biochemical Society Transactions 28, Nr. 5 (01.10.2000): A173. http://dx.doi.org/10.1042/bst028a173.

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Canham, Hugo. „EMBODIED BLACK RAGE“. Du Bois Review: Social Science Research on Race 14, Nr. 2 (2017): 427–45. http://dx.doi.org/10.1017/s1742058x17000066.

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AbstractExamining two sets of archived materials that include a corpus of narratives that reflect on the period of apartheid in South Africa and posters used by anti-apartheid activists, the paper teases out the operations of racism and the manifestations of rage on the Black body. Critical discourse analysis and affect as theory and method are applied to trace the work of racism and its affective consequences and resistances. Here affect is deployed to read the terrain of the corporeal and the discursive. Black rage is seen as a response to White supremacy and it has the following outcomes: it can have destructive consequences, can enable psychological release of pent up anger, and can simultaneously be an expression of self-love.
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Belinskaia, Daria A., Richard O. Jenkins und Nikolay V. Goncharov. „Molecular Basis for the Involvement of Mammalian Serum Albumin in the AGE/RAGE Axis: A Comprehensive Computational Study“. International Journal of Molecular Sciences 25, Nr. 6 (11.03.2024): 3204. http://dx.doi.org/10.3390/ijms25063204.

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In mammals, glycated serum albumin (gSA) contributes to the pathogenesis of many metabolic diseases by activating the receptors (RAGE) for advanced glycation end products (AGEs). Many aspects of the gSA–RAGE interaction remain unknown. The purpose of the present paper was to study the interaction of glycated human albumin (gHSA) with RAGE using molecular modeling methods. Ten models of gHSA modified with different lysine residues to carboxymethyl-lysines were prepared. Complexes of gHSA–RAGE were obtained by the macromolecular docking method with subsequent molecular dynamics simulation (MD). According to the MD, the RAGE complexes with gHSA glycated at Lys233, Lys64, Lys525, Lys262 and Lys378 are the strongest. Three-dimensional models of the RAGE dimers with gHSA were proposed. Additional computational experiments showed that the binding of fatty acids (FAs) to HSA does not affect the ability of Lys525 (the most reactive lysine) to be glycated. In contrast, modification of Lys525 reduces the affinity of albumin for FA. The interspecies differences in the molecular structure of albumin that may affect the mechanism of the gSA–RAGE interaction were discussed. The obtained results will help us to learn more about the molecular basis for the involvement of serum albumin in the AGE/RAGE axis and improve the methodology for studying cellular signaling pathways involving RAGE.
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Asadipooya, Kamyar, Kamran B. Lankarani, Rishi Raj und Mohammadreza Kalantarhormozi. „RAGE is a Potential Cause of Onset and Progression of Nonalcoholic Fatty Liver Disease“. International Journal of Endocrinology 2019 (18.09.2019): 1–11. http://dx.doi.org/10.1155/2019/2151302.

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Objective. Fatty liver is a rising global health concern, significantly increasing the burden of health care cost. Nonalcoholic fatty liver disease (NAFLD) has a correlation with metabolic syndrome and its complications. Method. We reviewed the literature regarding the mechanisms of developing NAFLD through AGE-RAGE signaling. Results. NAFLD, metabolic syndrome, and production of advanced glycation end-products (AGEs) share many common risk factors and appear to be connected. AGE induces production of the receptor for AGE (RAGE). AGE-RAGE interaction contributes to fat accumulation in the liver leading to inflammation, fibrosis, insulin resistance, and other complications of the fatty liver disease. The immune system, especially macrophages, has an important defense mechanism against RAGE pathway activities. Conclusion. Soluble form of RAGE (sRAGE) has the capability to reduce inflammation by blocking the interaction of AGE with RAGE. However, sRAGE has some limitations, and the best method of usage is probably autotransplantation of transfected stem cells or monocytes, as a precursor of macrophages and Kupffer cells, with a virus that carries sRAGE to alleviate the harmful effects of AGE-RAGE signaling in the settings of fatty liver disease.
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Hwang, J. S., J. Kim, H. S. Gong und G. H. Baek. „POS1144 INCREASED EXPRESSION OF RECEPTOR FOR ADVANCED GLYCATION END-PRODUCTS IN SARCOPENIC PATIENT SKELETAL MUSCLE“. Annals of the Rheumatic Diseases 81, Suppl 1 (23.05.2022): 900.2–901. http://dx.doi.org/10.1136/annrheumdis-2022-eular.1502.

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BackgroundAnimal studies suggest that advanced glycation end-products (AGEs) and their interaction with receptor for AGEs (RAGE) are involved in sarcopenia, but their relationship in human skeletal muscles has yet to be elucidated.ObjectivesWe aimed to determine whether RAGE expression in human skeletal muscle is associated with serum AGE levels and sarcopenia-related changes.MethodsWe reviewed 33 consecutive women (mean age, 65 years) with distal radius fracture who had consented to donate a sample of forearm flexor muscle for research purposes, which was taken during surgical fracture repair. The muscle RAGE expression was measured with immunohistochemistry staining and serum AGE levels using ELISA method. We compared RAGE expression and AGE levels in patients with and without sarcopenia. We also correlated RAGE expression with such clinical parameters as age, body mass index, bone mineral density (BMD), as well as sarcopenia-related changes, including grip strength, appendicular skeletal muscle mass, and muscle cross-sectional area (CSA) ratios.ResultsTwelve patients (36%) were diagnosed with sarcopenia according to the Asian Working Group for Sarcopenia. They had a significantly higher RAGE expression (p = 0.044) and AGE level (p < 0.001) than those without sarcopenia. The RAGE expression correlated significantly with a high serum AGE level (r = 0.510, p = 0.011) and correlated inversely with a muscle CSA ratio (r = -0.696, p < 0.001).ConclusionThis study shows that RAGE expression increases in sarcopenic patient skeletal muscles. This expression also correlates positively with serum AGE levels and inversely with muscle CSA ratios. Further studies are necessary to determine whether targeting RAGEs can be a therapeutic option for sarcopenia.References[1]Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: a review. Diabetologia. 2001; 44: 129-46.[2]Tabara Y, Ikezoe T, Yamanaka M et al. Advanced glycation end product accumulation is associated with low skeletal mass, weak muscle strength, and reduced bone density: the Nagahama study. J Gerontol A Biol Sci Med Sci. 2019; 74: 1446-53.[3]Riuzzi F, Sorci G, Sagheddu R, Chiappalupi S, Salvadori L, Donato R. RAGE in the pathophysiology of skeletal muscle. J Cachexia Sarcopenia Muscle. 2018; 9: 1213-34.Figure 1.Skeletal muscle tissue (x 7.0) obtained from (a) a 76-year-old female with receptor for advanced glycation end-products (RAGE) expression scoring 14, and (b) a 75-year-old female with RAGE expression scoring 50. Disparity between the percentage of fibers with signal intensity of 1+ (arrow) and those with signal intensity of 2+ (arrowhead) is obvious. Difference in the diameter and homogeneity of the muscle fibers imply the role of RAGE hyperexpression in sarcopenia.Disclosure of InterestsNone declared
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Belinskaia, D. A., und N. V. Goncharov. „Interaction of Glycated Albumin with Receptor for Glycation End Products According to Molecular Modeling Data“. Российский физиологический журнал им И М Сеченова 109, Nr. 12 (01.12.2023): 1810–31. http://dx.doi.org/10.31857/s0869813923120026.

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In diabetes mellitus (DM) patients, the accumulation of advanced glycation end products (AGE) leads to inflammation and oxidative stress through the activation of specific receptors for AGE (RAGE). Glycated albumin (gHSA) makes a significant contribution to the overall level of AGE in human body and, as a result, to the pathogenesis of DM and concomitant diseases. The mechanism of interaction of gHSA with RAGE is practically not studied. The purpose of the present paper is to study the binding of gHSA to RAGE using molecular modeling methods, to find the main sites of interaction and structural features of glycation sites that determine the efficiency of complex formation with RAGE. Ten gHSA models were constructed using molecular docking and molecular dynamics (MD) methods; each model corresponded to one modified lysine residue (carboxymethyl-lysine): Lys64, Lys73, Lys137, Lys233, Lys262, Lys317, Lys378, Lys525, Lys573, Lys574. Complexes of gHSA with the V-domain of RAGE were constructed using the macromolecular docking method, and their stability was studied using MD simulation. In the constructed gHSA models, the carboxyl groups of glycated Lys317 and Lys525 form intramolecular salt bridges with surrounding amino acids; in other cases, the carboxyl groups of the modified lysines are free to interact with positively charged amino acid residues on the RAGE surface. According to the macromolecular docking data and subsequent MD simulation, the complex of RAGE with gHSA glycated at Lys233 is most effective in terms of strength and specificity. Specific RAGE complexes with gHSA glycated at Lys317 and Lys574 are not formed. The obtained data on the interaction of gHSA with RAGE will help to understand the role of albumin in the pathophysiology of DM and advance towards the prevention and development of effective therapy for this disease.
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Vassiliev, P. M., A. A. Spasov, L. R. Yanaliyeva, A. N. Kochetkov, V. V. Vorfolomeyeva, V. G. Klochkov und D. T. Appazova. „Neural network modeling of multitarget RAGE inhibitory activity“. Biomeditsinskaya Khimiya 65, Nr. 2 (2019): 91–98. http://dx.doi.org/10.18097/pbmc20196502091.

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Based on the methodology of artificial neural networks, models describing the dependence of the level of RAGE inhibitory activity on the affinity of compounds for target proteins of the RAGE-NF-kB signal pathway have been costructed. A validated database of the structures and activity levels of 183 known compounds, which were tested for RAGE inhibitory activity was formed. The analysis of the AGE-RAGE signaling pathways was carried out, 14 key RAGE-NF-kB signal pathway nodes were found, for which 34 relevant target proteins were identified. A database of 66 valid 3D models of 22 target proteins of the RAGE-NF-kB signal chain was compiled. Ensemble molecular docking of 3D models of 183 known RAGE inhibitors into sites of 66 valid 3D models of 22 relevant RAGE target proteins was performed and minimum docking energies for each compound were determined for each target. According to the method of artificial multilayer perceptron neural networks, classification models were constructed to predict level of RAGE inhibitory activity based on the calculated affinity of compounds for significant target proteins of the RAGE-NF-kB signaling chain. The prognostic ability of these models of RAGE-inhibitory activity was evaluated, the maximum accuracy according to ROC-analysis was 90% for a high level of activity. The sensitivity analysis of the developed multitarget models were carried out, the most significant targets of the RAGE-NF-kB signal transmission chain were determined. It was found that for high level of RAGE inhibitory activity, the most significant biotargets are not AGE receptors, but eight signaling kinases of the RAGE-NF-kB pathway and transcription factor NF-kB1. Thus, it is suggested that known compounds with high RAGE-inhibitory activity are preferential inhibitors of signal kinases.
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Faisal, Muhammad Ali, Ika Kustiyah Oktaviyanti, Hidayat Sujuti und Achmad Rudijanto. „Virtual Screening of the Active Components of Garcinia mangostana Linn. Potentially Inhibiting the Interaction of Advanced Glycation End-products and their Receptor“. Open Access Macedonian Journal of Medical Sciences 8, A (21.11.2020): 921–27. http://dx.doi.org/10.3889/oamjms.2020.5505.

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BACKGROUND: Mangosteen (Garcinia mangostana L.) is a plant that contains various secondary metabolite compounds, one of which is xanthone. Xanthone in mangosteen has a variety of beneficial biological and medical effects, one of which is an antioxidative, anti-inflammatory, and antiapoptotic agent. AIM: The aim of the study was to perform the selection of any xanthone in mangosteen pericarp that have potentially inhibit the interaction of AGEs and RAGE. METHODS: The analysis was made in silico by docking method using software Hex 8.0. The docking was done between AGEs-RAGE, also between nine active compounds of G. mangostana with RAGE. The active compounds analyzed here were including α-mangostin, β-mangostin, γ-mangostin, mangostanol, garcinone D, 1,6-Dihydroxy-3,7-dimethoxy-2-(3-methylbut-2-enyl)-xanthone, gartanin, 1-isomangostin, and 3-isomangostin. Further analysis was performed to see the interactions formed between ligands with their receptors using software LigPlus+ and Discovery Studio 4.1. RESULTS: 1-isomangostin, 3-isomangostin, γ-mangostin, mangostanol, D-garcinone, and gartanin have potentially could inhibit the interaction and activity of imidazole in RAGE through a competitive binding mechanism. CONCLUSIONS: The inhibition of imidazole-RAGE activity by the mangosteen active components may inhibit the pathobiology of AGEs-RAGE axis.
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Dissertationen zum Thema "RAGE method"

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Lafon, Monique. „La nucleocapside du virus rabique : une nouvelle cible pour la reponse immunitaire et pour la therapie“. Paris 7, 1987. http://www.theses.fr/1987PA077219.

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Barret, Julien. „Clonage, ingénierie et transfert de grands fragments de génome chez Bacillus subtilis“. Electronic Thesis or Diss., Bordeaux, 2024. http://www.theses.fr/2024BORD0458.

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L’ingénierie des génomes des micro-organismes est devenue un standard dans les biotechnologies microbiennes. En 2010, des technologies prometteuses de biologie de synthèse utilisant la levure comme plateforme pour l’assemblage et l’ingénierie de génomes synthétiques bactériens suivi de leur transplantation dans une cellule receveuse ont vu le jour. Ces technologies ont conduit à la création des premières cellules synthétiques et ouvert de nouvelles voies vers la construction de cellules aux propriétés biologiques entièrement contrôlées. Le transfert de ces outils à des micro-organismes d’intérêt industriel comme la bactérie Gram+ Bacillus subtilis (Bsu), modèle dans le secteur des biotechnologies, constituerait une avancée majeure. C’est précisément l’objectif du projet ANR « Bacillus 2.0 », qui réunit deux équipes INRAE et qui se propose d’adapter l’ensemble de ces outils de biologie de synthèse à Bsu afin d’être en mesure de partir d’une conception, assistée par ordinateur, de génomes semi-synthétiques de Bsu jusqu’à l’obtention de nouvelles souches industrielles. Cependant, les premiers travaux réalisés sur ce projet ont montré que le génome entier de Bsu ne pouvait pas être cloné et maintenu en l’état dans la levure. Ces résultats risquaient de remettre en question la faisabilité du projet dans son ensemble et en particulier la pertinence d’utiliser la levure comme plateforme d’assemblage du génome semi-synthétique de Bsu.L’objectif de ma thèse a consisté à démontrer que la levure restait un hôte pertinent pour le projet « Bacillus 2.0 ». Elle s’est déclinée en 3 parties. Dans la première partie, une méthode de clonage de génome récemment développée au laboratoire et dénommée CReasPy-Fusion, a progressivement été adaptée à Bsu. Les résultats obtenus ont montré (i) le transfert possible d'ADN plasmidique entre protoplastes bactériens et sphéroplastes de levure, (ii) l'efficacité d'un système CRISPR-Cas9 porté par les cellules de levure pour capturer/modifier cet ADN plasmidique pendant la fusion Bsu/levure, puis (iii) l'efficacité de ce même système pour capturer des fragments de génome d’une centaine de kb à partir de trois souches différentes. Des observations en microscopie à fluorescence ont également été réalisées et ont mis en évidence deux types d’interactions qui permettraient de passer d’un contact protoplastes/sphéroplastes à un ADN bactérien cloné dans la levure. Dans la seconde partie de ma thèse, la méthode CReasPy-Fusion a été mise à profit pour tenter de cloner de grands fragments du génome de Bsu dans la levure. Des fragments génomiques jusqu’à ~1 Mb ont pu être clonés dans la levure, mais leur capture a nécessité l’ajout préalable d’un grand nombre d’ARS sur le génome de Bsu pour stabiliser les constructions génétiques. La dernière partie a été l’adaptation de la méthode RAGE à Bsu. Cette méthode permet le transfert, non pas d’un génome entier mais de portions de génomes bactériens depuis la levure vers la bactérie à éditer. Une preuve de concept a été réalisée avec l’échange d’un premier fragment de génome de 155 kb par une version réduite de 44 kb.En conclusion, les travaux réalisés au cours de cette thèse ont montré la pertinence d’utiliser la levure comme plateforme d’ingénierie dans les modifications à grande échelle du génome de Bsu. D’une part, nous avons montré que des fragments d’une centaine de kb peuvent être clonés dans la levure, modifiés et transférés dans une cellule receveuse de façon à générer des Bsu mutants. Cette stratégie offre une véritable alternative à la transplantation de génome. D’autre part, nous avons montré que de grands fragments du génome de Bsu (jusqu’à 1Mb) peuvent également être clonés dans la levure à condition de contenir de nombreux ARS dans leurs séquences. Grâce à ces résultats, le clonage d’un génome réduit de Bsu chez la levure est redevenu un objectif réalisable
Genome engineering of microorganisms has become a standard in microbial biotechnology. In 2010, promising synthetic biology technologies using yeast as a platform for the assembly and engineering of synthetic bacterial genomes followed by their transplantation into a recipient cell have emerged. These technologies have led to the creation of the first synthetic cells and opened new avenues towards the construction of cells with fully controlled biological properties. Transferring these tools to microorganisms of industrial interest such as the Gram+ bacterium Bacillus subtilis (Bsu), a model in the biotechnology sector, would be a major step forward. This is precisely the aim of the ANR "Bacillus 2.0" project, which brings together two INRAE teams and aims to adapt all these synthetic biology tools to Bsu so as to be able to go from computer-aided design of semi-synthetic Bsu genomes to the production of new industrial strains. However, initial work on this project showed that the entire Bsu genome could not be cloned and maintained in yeast in its current state. These results threatened to call into question the feasibility of the entire project and, in particular, the relevance of using yeast as a platform for assembling the semi-synthetic Bsu genome.The goal of my thesis was to demonstrate that yeast remained a relevant host for the Bacillus 2.0 project. It was divided into 3 parts. In the first part, a genome cloning method recently developed in the laboratory, called CReasPy-Fusion, was progressively adapted to Bsu. The results obtained showed (i) the possible transfer of plasmid DNA between bacterial protoplasts and yeast spheroplasts, (ii) the efficiency of a CRISPR-Cas9 system carried by yeast cells to capture/modify this plasmid DNA during Bsu/yeast fusion, and then (iii) the efficiency of the same system to capture genomic fragments of about a hundred kb from three different strains. Fluorescence microscopy observations were also carried out revealing two types of interaction that would enable the transition from protoplast/spheroplast contact to cloned bacterial DNA in yeast. In the second part of my thesis, the CReasPy-Fusion method was used in an attempt to clone large Bsu genome fragments in yeast. Genomic fragments of up to ~1 Mb could be cloned in yeast, but their capture required the prior addition of a large number of ARS to the Bsu genome to stabilize the genetic constructs. The final part was the adaptation of the RAGE method to Bsu. This method allow the transfer, not of a whole genome, but of portions of bacterial genomes from yeast to the bacteria to be edited. Proof of concept was achieved by exchanging a 155 kb genome fragment with a reduced 44 kb version.In conclusion, the work carried out during this thesis has shown the relevance of using yeast as an engineering platform for large-scale modifications of the Bsu genome. On the one hand, we have shown that fragments of around 100 kb can be cloned in yeast, modified and transferred into a recipient cell to generate Bsu mutants. This strategy offers a real alternative to genome transplantation. On the other hand, we have shown that large fragments of the Bsu genome (up to 1 Mb) can also be cloned in yeast, provided they contain numerous ARS in their sequences. Thanks to these results, cloning a reduced Bsu genome in yeast has once again become an achievable goal
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Neuman, Arthur James III. „Regularization Methods for Ill-posed Problems“. Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1273611079.

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Horová, Denisa. „Ocenění privátní firmy“. Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-75249.

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The master thesis deals with the appreciation of medical practice premises. Methods which are used, described and analyzed in the thesis, represent the standard expert methods for business valuation. These are supplemented by specific procedures used for determining the value of medical practices in particular. The work also describes the health care system of the Czech Republic, the methods and sources of payment for medical treatments, value generators in medical practices and basic procedures for identifying approximate value of medical practice, eventually of its goodwill. On practical example of medical practice there are described and applied also the scientific yield methods, which can derive the value of this type of business quite accurately. In the conclusion there are also discussed some currently used but not entirely accurate valuation processes.
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FONSECA, GABRIEL P. „Monte Carlo modeling of the patient and treatment delivery complexities for high dose rate brachytherapy“. reponame:Repositório Institucional do IPEN, 2015. http://repositorio.ipen.br:8080/xmlui/handle/123456789/25298.

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Submitted by Claudinei Pracidelli (cpracide@ipen.br) on 2015-12-10T16:54:22Z No. of bitstreams: 0
Made available in DSpace on 2015-12-10T16:54:22Z (GMT). No. of bitstreams: 0
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Tese (Doutorado em Tecnologia Nuclear)
IPEN/T
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
FAPESP:11/01913-4
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Steed, Arnold F. „A heuristic search method of selecting range-range sites for hydrographic surveys“. Thesis, Monterey, California. Naval Postgraduate School, 1991. http://hdl.handle.net/10945/27078.

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Tautenhahn, Martin. „Lokalisierung für korrelierte Anderson Modelle“. Master's thesis, Universitätsbibliothek Chemnitz, 2007. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-200701584.

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Im Fokus dieser Diplomarbeit steht ein korreliertes Anderson Modell. Unser Modell beschreibt kurzreichweitige Einzelplatzpotentiale, wobei negative Korrelationen zugelassen werden. Für dieses korrelierte Modell wird mittels der fraktionalen Momentenmethode im Falle genügend großer Unordnung exponentieller Abfall der Greenschen Funktion bewiesen. Anschließend wird daraus für den nicht korrelierten Spezialfall Anderson Lokalisierung bewiesen
This thesis (diploma) is devoted to a correlated Anderson model. Our model describes short range single site potentials, whereby negative correlations become certified. For this correlated model exponential decay of the Greens' function is proven in the case sufficient large disorder according to the fractional moment method. Subsequently, we prove Anderson localization for the not correlated special case
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Li, Tuo. „Fingerprint Identification by Improved Method of Minutiae Matching“. Miami University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=miami1484672769912832.

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Aulí, Llinàs Francesc. „Model-Based JPEG2000 rate control methods“. Doctoral thesis, Universitat Autònoma de Barcelona, 2006. http://hdl.handle.net/10803/5806.

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Aquesta recerca està centrada en l'escalabilitat qualitativa de l'estàndard de compressió d'imatges JPEG2000. L'escalabilitat qualitativa és una característica fonamental que permet el truncament de la tira de bits a diferents punts sense penalitzar la qualitat de la imatge recuperada. L'escalabilitat qualitativa és també fonamental en transmissions d'imatges interactives, ja que permet la transmissió de finestres d'interès a diferents qualitats.
El JPEG2000 aconsegueix escalabilitat qualitativa a partir del mètode de control de factor de compressió utilitzat en el procés de compressió, que empotra capes de qualitat a la tira de bits. En alguns escenaris, aquesta arquitectura pot causar dos problemàtiques: per una banda, quan el procés de codificació acaba, el número i distribució de les capes de qualitat és permanent, causant una manca d'escalabilitat qualitativa a tires de bits amb una o poques capes de qualitat. Per altra banda, el mètode de control de factor de compressió construeix capes de qualitat considerant la optimització de la raó distorsió per l'àrea completa de la imatge, i això pot provocar que la distribució de les capes de qualitat per la transmissió de finestres d'interès no sigui adequada.
Aquesta tesis introdueix tres mètodes de control de factor de compressió que proveeixen escalabilitat qualitativa per finestres d'interès, o per tota l'àrea de la imatge, encara que la tira de bits contingui una o poques capes de qualitat. El primer mètode està basat en una simple estratègia d'entrellaçat (CPI) que modela la raó distorsió a partir d'una aproximació clàssica. Un anàlisis acurat del CPI motiva el segon mètode, basat en un ordre d'escaneig invers i una concatenació de passades de codificació (ROC). El tercer mètode es beneficia dels models de raó distorsió del CPI i ROC, desenvolupant una novedosa aproximació basada en la caracterització de la raó distorsió dels blocs de codificació dins una subbanda (CoRD).
Els resultats experimentals suggereixen que tant el CPI com el ROC són capaços de proporcionar escalabilitat qualitativa a tires de bits, encara que continguin una o poques capes de qualitat, aconseguint un rendiment de codificació pràcticament equivalent a l'obtingut amb l'ús de capes de qualitat. Tot i això, els resultats del CPI no estan ben balancejats per les diferents raons de compressió i el ROC presenta irregularitats segons el corpus d'imatges. CoRD millora els resultats de CPI i ROC i aconsegueix un rendiment ben balancejat. A més, CoRD obté un rendiment de compressió una mica millor que l'aconseguit amb l'ús de capes de qualitat. La complexitat computacional del CPI, ROC i CoRD és, a la pràctica, negligible, fent-los adequats per el seu ús en transmissions interactives d'imatges.
This work is focused on the quality scalability of the JPEG2000 image compression standard. Quality scalability is an important feature that allows the truncation of the code-stream at different bit-rates without penalizing the coding performance. Quality scalability is also fundamental in interactive image transmissions to allow the delivery of Windows of Interest (WOI) at increasing qualities.
JPEG2000 achieves quality scalability through the rate control method used in the encoding process, which embeds quality layers to the code-stream. In some scenarios, this architecture might raise two drawbacks: on the one hand, when the coding process finishes, the number and bit-rates of quality layers are fixed, causing a lack of quality scalability to code-streams encoded with a single or few quality layers. On the other hand, the rate control method constructs quality layers considering the rate¬distortion optimization of the complete image, and this might not allocate the quality layers adequately for the delivery of a WOI at increasing qualities.
This thesis introduces three rate control methods that supply quality scalability for WOIs, or for the complete image, even if the code-stream contains a single or few quality layers. The first method is based on a simple Coding Passes Interleaving (CPI) that models the rate-distortion through a classical approach. An accurate analysis of CPI motivates the second rate control method, which introduces simple modifications to CPI based on a Reverse subband scanning Order and coding passes Concatenation (ROC). The third method benefits from the rate-distortion models of CPI and ROC, developing an approach based on a novel Characterization of the Rate-Distortion slope (CoRD) that estimates the rate-distortion of the code¬blocks within a subband.
Experimental results suggest that CPI and ROC are able to supply quality scalability to code-streams, even if they contain a single or few quality layers, achieving a coding performance almost equivalent to the one obtained with the use of quality layers. However, the results of CPI are unbalanced among bit-rates, and ROC presents an irregular coding performance for some corpus of images. CoRD outperforms CPI and ROC achieving well-balanced and regular results and, in addition, it obtains a slightly better coding performance than the one achieved with the use of quality layers. The computational complexity of CPI, ROC and CoRD is negligible in practice, making them suitable to control interactive image transmissions.
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Alshahrani, Mohammed Nasser D. „Statistical methods for rare variant association“. Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22436/.

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Deoxyribonucleic acid (DNA) sequencing allows researchers to conduct more complete assessments of low-frequency and rare genetic variants. In anticipation of the availability of next-generation sequencing data, there is increasing interest in investigating associations between complex traits and rare variants (RVs). In contrast to association studies of common variants (CVs), due to the low frequencies of RVs, common wisdom suggests that existing statistical tests for CVs might not work, motivating the recent development of several new tests that analyze RVs, most of which are based on the idea of pooling/collapsing RVs. Genome-wide association studies (GWAS) based on common SNPs gained more attention in the last few years and have been regularly used to examine complex genetic compositions of diseases and quantitative traits. GWASs have not discovered everything associated with diseases and genetic variations. However, recent empirical evidence has demonstrated that low-frequency and rare variants are, in fact, connected to complex diseases. This thesis will focus on the study of rare variant association. Aggregation tests, where multiple rare variants are analyzed jointly, have incorporated weighting schemes on variants. However, their power is very much dependent on the weighting scheme. I will address three topics in this thesis: the definition of rare variants and their call file (VCF) and a description of the methods that have been used in rare variant analysis. Finally, I will illustrate challenges involved in the analysis of rare variants and propose different weighting schemes for them. Therefore, since the efficiency of rare variant studies might be considerably improved by the application of an appropriate weighting scheme, choosing the proper weighting scheme is the topic of the thesis. In the following chapters, I will propose different weighting schemes, where weights are applied at the level of the variant, the individual or the cell (i.e. the individual genotype call), as well as a weighting scheme that can incorporate quality measures for variants (i.e., a quality score for variant calls) and cells (i.e., genotype quality).
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Bücher zum Thema "RAGE method"

1

Center, Lewis Research, Hrsg. Semiempirical method of determining flow coefficients for pitot rake mass flow rate measurements. [Cleveland, Ohio: National Aeronautics and Space Administration, Lewis Research Center, 1985.

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Thomas, Emel. Critical Race Qualitative Methods. Herausgegeben von Emel Thomas. 1 Oliver’s Yard, 55 City Road, London EC1Y 1SP United Kingdom: SAGE Publications Ltd, 2024. http://dx.doi.org/10.4135/9781529691535.

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Ryf, Christian. Range of motion: AO Neutral-0 Method : measurement and documentation = AO Neutral-0 Methode : messung und dokumentation. Stuttgart: Thieme, 1999.

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Michael, Peel, Hrsg. Rape as a method of torture. London: Medical Foundation for the Care of Victims of Torture, 2004.

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Steed, Arnold F. A heuristic search method of selecting range-range sites for hydrographic surveys. Monterey, Calif: Naval Postgraduate School, 1991.

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Ledesma, María C., Vanessa Johnson Ojeda, Shawn R. Coon und Laurence Parker. Critical Race Theory and Qualitative Methods. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003430483.

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Glick, Robert L. An improved closed burner method. New York: American Institute of Aeronautics and Astronautics, 1990.

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Savino, John O. Rape investigation handbook. 2. Aufl. Burlington, MA: Academic Press, 2011.

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Özale, Ümit. Measuring exchange rate misalignment. Cairo, Egypt: Economic Research Forum for the Arab Countries, Iran & Turkey, 2002.

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Rubino, Gerardo, und Bruno Tuffin, Hrsg. Rare Event Simulation using Monte Carlo Methods. Chichester, UK: John Wiley & Sons, Ltd, 2009. http://dx.doi.org/10.1002/9780470745403.

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Buchteile zum Thema "RAGE method"

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Faulkner, Sandra L. „My middle-aged rage burns the template in front of the Provost's office after the assessment meeting“. In Poetry, Method and Education Research, 104–5. Abingdon, Oxon ; New York, NY : Routledge, 2020.: Routledge, 2020. http://dx.doi.org/10.4324/9780429202117-10.

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N. Jazar, Reza. „Energy-Rate Method“. In Approximation Methods in Science and Engineering, 473–518. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0480-9_6.

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Rouhiainen, Ari, Juha Kuja-Panula, Sarka Tumova und Heikki Rauvala. „RAGE-Mediated Cell Signaling“. In Methods in Molecular Biology, 239–63. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-230-8_15.

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Sterenczak, Katharina Anna, Ingo Nolte und Hugo Murua Escobar. „RAGE Splicing Variants in Mammals“. In Methods in Molecular Biology, 265–76. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-230-8_16.

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Wankat, Phillip C. „Electrophoretic Separation Methods“. In Rate-Controlled Separations, 550–620. Dordrecht: Springer Netherlands, 1990. http://dx.doi.org/10.1007/978-94-010-9724-6_11.

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Wankat, Phillip C. „Electrophoretic Separation Methods“. In Rate-Controlled Separations, 550–620. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-1342-7_11.

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Witelski, Thomas, und Mark Bowen. „Rate Equations“. In Methods of Mathematical Modelling, 3–21. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-23042-9_1.

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Mitsuhashi, Jun. „Growth Rate“. In Invertebrate Tissue Culture Methods, 347–51. Tokyo: Springer Japan, 2002. http://dx.doi.org/10.1007/978-4-431-67875-5_36.

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Wang, Zhiguo, und Baofeng Yang. „RAKE Assay“. In MicroRNA Expression Detection Methods, 281–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04928-6_21.

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Chakraborty, Shankar, Prasenjit Chatterjee und Partha Protim Das. „Range of Value (Rov) Method“. In Multi-Criteria Decision-Making Methods in Manufacturing Environments, 231–36. New York: Apple Academic Press, 2023. http://dx.doi.org/10.1201/9781003377030-21.

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Konferenzberichte zum Thema "RAGE method"

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Seitz, Peter. „BIM Basics in an International Context“. In IABSE Congress, San José 2024: Beyond Structural Engineering in a Changing World, 635–42. Zurich, Switzerland: International Association for Bridge and Structural Engineering (IABSE), 2024. https://doi.org/10.2749/sanjose.2024.0635.

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<p>Building Information Modelling (BIM) is all the rage these days, but hardly anyone understands what it really means. Even internationally, BIM has different meanings. The BIM method is important for future construction projects, so we need to know how BIM is understood in an international context.</p><p>This paper briefly outlines BIM's origins, followed by a definition of its meaning. For some countries, it shows which organization is responsible for the BIM definitions and which initiatives exist to inform about the application of BIM. Some terms and abbreviations that are important when working with BIM are explained. Use cases are explained, and a reference to software tools is given.</p><p>This paper will help people and organizations start using the BIM method for everyday use. The BIM method is only one part of the digitalisation process in the construction industry, but it can help organize information and implement an efficient way of collaboration with different disciplines.</p>
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Li, Zongyan, und Yujie Ouyang. „A Method for Resolving Range Ambiguity of High-Frame-Rate Signals Based on Radial Velocity Constraint“. In 2024 OES China Ocean Acoustics (COA), 1–5. IEEE, 2024. http://dx.doi.org/10.1109/coa58979.2024.10723448.

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Ozdemir, O. C., und S. Muftu. „Novel Method of Predicting Deposition Efficiency in Cold Spray by Incorporating Sphericity into 1D Numerical Models“. In ITSC2022. DVS Media GmbH, 2022. http://dx.doi.org/10.31399/asm.cp.itsc2022p0389.

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Abstract In cold spray (CS) additive manufacturing process, micrometer scale particles accelerated through a supersonic nozzle are targeted on a surface with velocities in the rage of 300-1500 m/s in solid state. The impact energy of the particles leads them to deform plastically with high shear energy near the impact interface and adhere to the surface metallurgically, mechanically, and chemically. Using CS, deposition of metals, metal matrix composites, and polymers are achieved with high adhesive/cohesive strength and low porosity. Sensitivity of the CS additive manufacturing process to the variabilities in the process parameters are still being understood. Among the process parameters, particle morphology can have significant implications on drag forces, and therefore, on the particle impact velocity. This in turn affects the deposition efficiency (DE) and the quality of products. In this work, a new approach is introduced for computing DE by incorporating particle sphericity and its variation into one-dimensional numerical models. Size, sphericity, and the variability of size and sphericity of aluminum, copper, titanium, and tantalum particles are measured from static optical microscope images. The data is used for predicting impact velocity, temperature, and DE. The model results are then compared with particle velocity measurements.
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Coder, James. „Effects of Transition Modeling on the Simulation of Helicopter Rotor Hubs“. In Vertical Flight Society 75th Annual Forum & Technology Display. The Vertical Flight Society, 2019. http://dx.doi.org/10.4050/f-0075-2019-14522.

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Helicopter rotor hubs are geometrically complex components that experience a wide rage of aerodynamic behaviors and flow physics. This includes strong unsteadiness, large amounts of separation, laminar-turbulent transition, and interactional aerodynamic behaviors (Ref. 1). At high forward flight speeds (high advance ratios), the parasitic drag of the hub accounts for O(30%) of the total power required to fly (Ref. 1). A common method for characterizing this contribution is the hub drag factor, Kfe, which correlates the flat-plate area of the hub with the helicopter gross weight and functions as a technology factor (Ref. 2). In a recent assessment of needs for future vertical lift systems, Ormiston suggested that the hub drag factor needs to be reduced from the current state of the art of Kfe = 0.5 down to a value 0.2 (Ref. 3).
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Giordana, Alejandro A., Enrique E. Sicre und Ricardo Duchowicz. „FBG wide-range and high rate interrogation method“. In 2014 IEEE Biennial Congress of Argentina (ARGENCON). IEEE, 2014. http://dx.doi.org/10.1109/argencon.2014.6868491.

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Qinghao, Zhu, und Yu Xueyong. „A Method of Target Range Determination from Bearing Rate“. In 2012 International Conference on Computer Science and Service System (CSSS). IEEE, 2012. http://dx.doi.org/10.1109/csss.2012.98.

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Tamakuwala, Jimmy B. „New Low Complexity Variance Method for Automatic Modulation Classification and Comparison with Maximum Likelihood Method“. In 2019 International Conference on Range Technology (ICORT). IEEE, 2019. http://dx.doi.org/10.1109/icort46471.2019.9069612.

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Luo, Wei, und Henri Maitre. „Quality assessment of a model oriented stereo method“. In Close-Range Photogrammetry Meets Machine Vision. SPIE, 1990. http://dx.doi.org/10.1117/12.2294309.

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Davis, Wayne A., Louis Paquette, Robert Stampfler und Terry M. Caelli. „A new camera calibration method for robotic vision“. In Close-Range Photogrammetry Meets Machine Vision. SPIE, 1990. http://dx.doi.org/10.1117/12.2294327.

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da Silva, Irineu. „Vectorization from aerial photographs applying the Hough transform method“. In Close-Range Photogrammetry Meets Machine Vision. SPIE, 1990. http://dx.doi.org/10.1117/12.2294366.

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Berichte der Organisationen zum Thema "RAGE method"

1

Stone, M. E. Evaluation Of Methods To Measure Hydrogen Generation Rate In A Shielded Cell Environment And A Method Recommendation. Office of Scientific and Technical Information (OSTI), November 2012. http://dx.doi.org/10.2172/1055580.

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Bruce. L51942 Refinement of Cooling Rate Prediction Methods for In-Service Welds. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), Juli 2003. http://dx.doi.org/10.55274/r0010435.

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Welds made onto in-service pipeline are particularly susceptible to hydrogen cracking because of the fast weld cooling rates that tend to result from the ability of the flowing contents to remove heat from the pipe wall. The most commonly used procedures for controlling the risk of hydrogen cracking rely on the use of a sufficiently high heat input level. Two methods currently exist for predicting required heat input levels for welds made onto in-service pipelines: thermal analysis computer modeling and the heat-sink capacity measurement method. The objective of this project was to refine these two complementary methods, and to investigate alternative approaches. The project was divided into three distinct tasks: further refinement of the PRCI Thermal Analysis Model for Hot Tap Welding, standardization of heat-sink capacity measurement, and investigation of alternative approaches to cooling rate prediction. The primary link between the PRCI model and the heat-sink capacity measurement method is the ability of the model to predict the heat-sink capacity of an operating pipeline. Detailed descriptions of user interface modifications required to incorporate the ability to enter the individual heating parameters of interest and have the model calculate the heating rate were developed.
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Gedeon, S. R. Basis for dose rate to curie assay method. Office of Scientific and Technical Information (OSTI), Oktober 1996. http://dx.doi.org/10.2172/332175.

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Downing, W. Logan, Howell Li, William T. Morgan, Cassandra McKee und Darcy M. Bullock. Using Probe Data Analytics for Assessing Freeway Speed Reductions during Rain Events. Purdue University, 2021. http://dx.doi.org/10.5703/1288284317350.

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Rain impacts roadways such as wet pavement, standing water, decreased visibility, and wind gusts and can lead to hazardous driving conditions. This study investigates the use of high fidelity Doppler data at 1 km spatial and 2-minute temporal resolution in combination with commercial probe speed data on freeways. Segment-based space-mean speeds were used and drops in speeds during rainfall events of 5.5 mm/hour or greater over a one-month period on a section of four to six-lane interstate were assessed. Speed reductions were evaluated as a time series over a 1-hour window with the rain data. Three interpolation methods for estimating rainfall rates were tested and seven metrics were developed for the analysis. The study found sharp drops in speed of more than 40 mph occurred at estimated rainfall rates of 30 mm/hour or greater, but the drops did not become more severe beyond this threshold. The average time of first detected rainfall to impacting speeds was 17 minutes. The bilinear method detected the greatest number of events during the 1-month period, with the most conservative rate of predicted rainfall. The range of rainfall intensities were estimated between 7.5 to 106 mm/hour for the 39 events. This range was much greater than the heavy rainfall categorization at 16 mm/hour in previous studies reported in the literature. The bilinear interpolation method for Doppler data is recommended because it detected the greatest number of events and had the longest rain duration and lowest estimated maximum rainfall out of three methods tested, suggesting the method balanced awareness of the weather conditions around the roadway with isolated, localized rain intensities.
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Nguyen, Hoa G., und Michael R. Blackburn. A Simple Method for Range Finding via Laser Triangulation. Fort Belvoir, VA: Defense Technical Information Center, Januar 1995. http://dx.doi.org/10.21236/ada292529.

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Critchley, James, und Paramsothy Jayakumar. An Abstract Multi-Rate Method for Vehicle Dynamics Simulation. Fort Belvoir, VA: Defense Technical Information Center, Januar 2012. http://dx.doi.org/10.21236/ada587360.

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Burchett, Bradley. Spark Range Data Reduction Using a Gauss Collocation Method. Aberdeen Proving Ground, MD: DEVCOM Army Research Laboratory, September 2021. http://dx.doi.org/10.21236/ad1147900.

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Rossi, Jose Luiz, Carlos Piccioni, Marina Rossi und Daniel Cuajeiro. Brazilian Exchange Rate Forecasting in High Frequency. Inter-American Development Bank, September 2022. http://dx.doi.org/10.18235/0004488.

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We investigated the predictability of the Brazilian exchange rate at High Frequency (1, 5 and 15 minutes), using local and global economic variables as predictors. In addition to the Linear Regression method, we use Machine Learning algorithms such as Ridge, Lasso, Elastic Net, Random Forest and Gradient Boosting. When considering contemporary predictors, it is possible to outperform the Random Walk at all frequencies, with local economic variables having greater predictive power than global ones. Machine Learning methods are also capable of reducing the mean squared error. When we consider only lagged predictors, it is possible to beat the Random Walk if we also consider the Brazilian Real futures as an additional predictor, for the frequency of one minute and up to two minutes ahead, confirming the importance of the Brazilian futures market in determining the spot exchange rate.
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Fernández-Villaverde, Jesús, und Oren Levintal. Solution Methods for Models with Rare Disasters. Cambridge, MA: National Bureau of Economic Research, Februar 2016. http://dx.doi.org/10.3386/w21997.

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Libert, John M., Shahram Orandi, John D. Grantham und Michael D. Garris. A Spectral Analytic Method for Fingerprint Image Sample Rate Estimation. National Institute of Standards and Technology, Februar 2014. http://dx.doi.org/10.6028/nist.ir.7968.

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