Thematische Bibliographien / Rag rug

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „Rag rug“

Autor: Grafiati
Veröffentlicht am 29. Juni 2021
Zuletzt aktualisiert am 5. Februar 2022

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Zeitschriftenartikel zum Thema "Rag rug"

1

Steedman, Carolyn. „What a Rag Rug Means“. Journal of Material Culture 3, Nr. 3 (November 1998): 259–81. http://dx.doi.org/10.1177/135918359800300301.

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Lee, Minji, Jong Hyun Kim, Ina Yoon, Chulho Lee, Mohammad Fallahi Sichani, Jong Soon Kang, Jeonghyun Kang et al. „Coordination of the leucine-sensing Rag GTPase cycle by leucyl-tRNA synthetase in the mTORC1 signaling pathway“. Proceedings of the National Academy of Sciences 115, Nr. 23 (21.05.2018): E5279—E5288. http://dx.doi.org/10.1073/pnas.1801287115.

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A protein synthesis enzyme, leucyl-tRNA synthetase (LRS), serves as a leucine sensor for the mechanistic target of rapamycin complex 1 (mTORC1), which is a central effector for protein synthesis, metabolism, autophagy, and cell growth. However, its significance in mTORC1 signaling and cancer growth and its functional relationship with other suggested leucine signal mediators are not well-understood. Here we show the kinetics of the Rag GTPase cycle during leucine signaling and that LRS serves as an initiating “ON” switch via GTP hydrolysis of RagD that drives the entire Rag GTPase cycle, whereas Sestrin2 functions as an “OFF” switch by controlling GTP hydrolysis of RagB in the Rag GTPase–mTORC1 axis. The LRS–RagD axis showed a positive correlation with mTORC1 activity in cancer tissues and cells. The GTP–GDP cycle of the RagD–RagB pair, rather than the RagC–RagA pair, is critical for leucine-induced mTORC1 activation. The active RagD–RagB pair can overcome the absence of the RagC–RagA pair, but the opposite is not the case. This work suggests that the GTPase cycle of RagD–RagB coordinated by LRS and Sestrin2 is critical for controlling mTORC1 activation, and thus will extend the current understanding of the amino acid-sensing mechanism.
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Shen, Kuang, und David M. Sabatini. „Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms“. Proceedings of the National Academy of Sciences 115, Nr. 38 (04.09.2018): 9545–50. http://dx.doi.org/10.1073/pnas.1811727115.

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The mechanistic target of rapamycin complex 1 (mTORC1) growth pathway detects nutrients through a variety of sensors and regulators that converge on the Rag GTPases, which form heterodimers consisting of RagA or RagB tightly bound to RagC or RagD and control the subcellular localization of mTORC1. The Rag heterodimer uses a unique “locking” mechanism to stabilize its active (GTPRagA–RagCGDP) or inactive (GDPRagA–RagCGTP) nucleotide states. The Ragulator complex tethers the Rag heterodimer to the lysosomal surface, and the SLC38A9 transmembrane protein is a lysosomal arginine sensor that upon activation stimulates mTORC1 activity through the Rag GTPases. How Ragulator and SLC38A9 control the nucleotide loading state of the Rag GTPases remains incompletely understood. Here we find that Ragulator and SLC38A9 are each unique guanine exchange factors (GEFs) that collectively push the Rag GTPases toward the active state. Ragulator triggers GTP release from RagC, thus resolving the locked inactivated state of the Rag GTPases. Upon arginine binding, SLC38A9 converts RagA from the GDP- to the GTP-loaded state, and therefore activates the Rag GTPase heterodimer. Altogether, Ragulator and SLC38A9 act on the Rag GTPases to activate the mTORC1 pathway in response to nutrient sufficiency.
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Naik, Abani Kanta, Aaron T. Byrd, Aaron C. K. Lucander und Michael S. Krangel. „Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes“. Journal of Experimental Medicine 216, Nr. 1 (13.12.2018): 231–43. http://dx.doi.org/10.1084/jem.20181402.

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Expression of Rag1 and Rag2 is tightly regulated in developing T cells to mediate TCR gene assembly. Here we have investigated the molecular mechanisms governing the assembly and disassembly of a transcriptionally active RAG locus chromatin hub in CD4+CD8+ thymocytes. Rag1 and Rag2 gene expression in CD4+CD8+ thymocytes depends on Rag1 and Rag2 promoter activation by a distant antisilencer element (ASE). We identify GATA3 and E2A as critical regulators of the ASE, and Runx1 and E2A as critical regulators of the Rag1 promoter. We reveal hierarchical assembly of a transcriptionally active chromatin hub containing the ASE and RAG promoters, with Rag2 recruitment and expression dependent on assembly of a functional ASE–Rag1 framework. Finally, we show that signal-dependent down-regulation of RAG gene expression in CD4+CD8+ thymocytes depends on Ikaros and occurs with disassembly of the RAG locus chromatin hub. Our results provide important new insights into the molecular mechanisms that orchestrate RAG gene expression in developing T cells.
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Anandapadamanaban, Madhanagopal, Glenn R. Masson, Olga Perisic, Alex Berndt, Jonathan Kaufman, Chris M. Johnson, Balaji Santhanam, Kacper B. Rogala, David M. Sabatini und Roger L. Williams. „Architecture of human Rag GTPase heterodimers and their complex with mTORC1“. Science 366, Nr. 6462 (10.10.2019): 203–10. http://dx.doi.org/10.1126/science.aax3939.

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The Rag guanosine triphosphatases (GTPases) recruit the master kinase mTORC1 to lysosomes to regulate cell growth and proliferation in response to amino acid availability. The nucleotide state of Rag heterodimers is critical for their association with mTORC1. Our cryo–electron microscopy structure of RagA/RagC in complex with mTORC1 shows the details of RagA/RagC binding to the RAPTOR subunit of mTORC1 and explains why only the RagAGTP/RagCGDP nucleotide state binds mTORC1. Previous kinetic studies suggested that GTP binding to one Rag locks the heterodimer to prevent GTP binding to the other. Our crystal structures and dynamics of RagA/RagC show the mechanism for this locking and explain how oncogenic hotspot mutations disrupt this process. In contrast to allosteric activation by RHEB, Rag heterodimer binding does not change mTORC1 conformation and activates mTORC1 by targeting it to lysosomes.
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Eastman, Quinn M., Isabelle J. Villey und David G. Schatz. „Detection of RAG Protein-V(D)J Recombination Signal Interactions Near the Site of DNA Cleavage by UV Cross-Linking“. Molecular and Cellular Biology 19, Nr. 5 (01.05.1999): 3788–97. http://dx.doi.org/10.1128/mcb.19.5.3788.

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ABSTRACT V(D)J recombination is initiated by double-strand cleavage at recombination signal sequences (RSSs). DNA cleavage is mediated by the RAG1 and RAG2 proteins. Recent experiments describing RAG protein-RSS complexes, while defining the interaction of RAG1 with the nonamer, have not assigned contacts immediately adjacent to the site of DNA cleavage to either RAG polypeptide. Here we use UV cross-linking to define sequence- and site-specific interactions between RAG1 protein and both the heptamer element of the RSS and the coding flank DNA. Hence, RAG1-DNA contacts span the site of cleavage. We also detect cross-linking of RAG2 protein to some of the same nucleotides that cross-link to RAG1, indicating that, in the binding complex, both RAG proteins are in close proximity to the site of cleavage. These results suggest how the heptamer element, the recognition surface essential for DNA cleavage, is recognized by the RAG proteins and have implications for the stoichiometry and active site organization of the RAG1-RAG2-RSS complex.
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Hall, Lucinda M. C., Stuart C. Fawell, Xiaoju Shi, Marie-Claire Faray-Kele, Joseph Aduse-Opoku, Robert A. Whiley und Michael A. Curtis. „Sequence Diversity and Antigenic Variation at the rag Locus of Porphyromonas gingivalis“. Infection and Immunity 73, Nr. 7 (Juli 2005): 4253–62. http://dx.doi.org/10.1128/iai.73.7.4253-4262.2005.

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ABSTRACT The rag locus of Porphyromonas gingivalis W50 encodes RagA, a predicted tonB-dependent receptor protein, and RagB, a lipoprotein that constitutes an immunodominant outer membrane antigen. The low G+C content of the locus, an association with mobility elements, and an apparent restricted distribution in the species suggested that the locus had arisen by horizontal gene transfer. In the present study, we have demonstrated that there are four divergent alleles of the rag locus. The original rag allele found in W50 was renamed rag-1, while three novel alleles, rag-2 to rag-4, were found in isolates lacking rag-1. The three novel alleles encoded variants of RagA with 63 to 71% amino acid identity to RagA1 and each other and variants of RagB with 43 to 56% amino acid identity. The RagA/B proteins have homology to numerous Bacteroides proteins, including SusC/D, implicated in polysaccharide uptake. Monoclonal and polyclonal antibodies raised against RagB1 of P. gingivalis W50 did not cross-react with proteins from isolates carrying different alleles. In a laboratory collection of 168 isolates, 26% carried rag-1, 36% carried rag-2, 25% carried rag-3, and 14% carried rag-4 (including the type strain, ATCC 33277). Restriction profiles of the locus in different isolates demonstrated polymorphism within each allele, some of which is accounted for by the presence or absence of insertion sequence elements. By reference to a previously published study on virulence in a mouse model (M. L. Laine and A. J. van Winkelhoff, Oral Microbiol. Immunol. 13:322-325, 1998), isolates that caused serious disease in mice were significantly more likely to carry rag-1 than other rag alleles.
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Petiniot, Lisa K., Zoë Weaver, Melanie Vacchio, Rhuna Shen, Danny Wangsa, Carrolee Barlow, Michael Eckhaus et al. „RAG-Mediated V(D)J Recombination Is Not Essential for Tumorigenesis in Atm-Deficient Mice“. Molecular and Cellular Biology 22, Nr. 9 (01.05.2002): 3174–77. http://dx.doi.org/10.1128/mcb.22.9.3174-3177.2002.

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ABSTRACT Atm-deficient mice die of malignant thymic lymphomas characterized by translocations within the Tcrα/δ locus, suggesting that tumorigenesis is secondary to aberrant responses to double-stranded DNA (dsDNA) breaks that occur during RAG-dependent V(D)J recombination. We recently demonstrated that development of thymic lymphoma in Atm−/− mice was not prevented by loss of RAG-2. Thymic lymphomas that developed in Rag2−/− Atm−/− mice contained multiple chromosomal abnormalities, but none of these involved the Tcrα/δ locus. These findings indicated that tumorigenesis in Atm−/− mice is mediated by chromosomal translocations secondary to aberrant responses to dsDNA breaks and that V(D)J recombination is an important, but not essential, event in susceptibility. In contrast to these findings, it was recently reported that Rag1−/− Atm−/− mice do not develop thymic lymphomas, a finding that was interpreted as demonstrating a requirement for RAG-dependent recombination in the susceptibility to tumors in Atm-deficient mice. To test the possibility that RAG-1 and RAG-2 differ in their roles in tumorigenesis, we studied Rag1−/− Atm−/− mice in parallel to our previous Rag2−/− Atm−/− study. We found that thymic lymphomas occur at high frequency in Rag1−/− Atm−/− mice and resemble those that occur in Rag2−/− Atm−/− mice. These results indicate that both RAG-1 and RAG-2 are necessary for tumorigenesis involving translocation in the Tcrα/δ locus but that Atm deficiency leads to tumors through a broader RAG-independent predisposition to translocation, related to a generalized defect in dsDNA break repair.
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Shi, Xiaoju, Shirley A. Hanley, Marie-Claire Faray-Kele, Stuart C. Fawell, Joseph Aduse-Opoku, Robert A. Whiley, Michael A. Curtis und Lucinda M. C. Hall. „The rag Locus of Porphyromonas gingivalis Contributes to Virulence in a Murine Model of Soft Tissue Destruction“. Infection and Immunity 75, Nr. 4 (05.02.2007): 2071–74. http://dx.doi.org/10.1128/iai.01785-06.

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ABSTRACT The rag locus of Porphyromonas gingivalis encodes a putative TonB-dependent outer membrane receptor, RagA, and a 55-kDa immunodominant antigen, RagB. Inactivation of either ragA or ragB prevented expression of both RagA and RagB. Both the ragA and ragB mutants were significantly less virulent than wild-type strains in a murine model of infection.
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Shetty, Keerthi, und David G. Schatz. „Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination“. Molecular and Cellular Biology 35, Nr. 21 (24.08.2015): 3701–13. http://dx.doi.org/10.1128/mcb.00219-15.

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V(D)J recombination is initiated by the binding of the RAG1 and RAG2 proteins to recombination signal sequences (RSSs) that consist of conserved heptamer and nonamer sequences separated by a spacer of either 12 or 23 bp. Here, we used RAG-inducible pro-B v-Abl cell lines in conjunction with chromatin immunoprecipitation to better understand the protein and RSS requirements for RAG recruitment to chromatin. Using a catalytic mutant form of RAG1 to prevent recombination, we did not observe cooperation between RAG1 and RAG2 in their recruitment to endogenous Jκ gene segments over a 48-h time course. Using retroviral recombination substrates, we found that RAG1 was recruited inefficiently to substrates lacking an RSS or containing a single RSS, better to substrates with two 12-bp RSSs (12RSSs) or two 23-bp RSSs (23RSSs), and more efficiently to a substrate with a 12/23RSS pair. RSS mutagenesis demonstrated a major role for the nonamer element in RAG1 binding, and correspondingly, a cryptic RSS consisting of a repeat of CA dinucleotides, which poorly re-creates the nonamer, was ineffective in recruiting RAG1. Our findings suggest that 12RSS-23RSS cooperation (the “12/23 rule”) is important not only for regulating RAG-mediated DNA cleavage but also for the efficiency of RAG recruitment to chromatin.
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Dissertationen zum Thema "Rag rug"

1

Tecza, Ashlee R. „RAG RUG WEAVING IN NORTHWESTERN PENNSYLVANIA, 1930-1970“. University of Akron / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=akron1185901168.

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Hakanen, Eva. „Återbrukets estetik - Uppländska trasryor : Förekomst, tillverkning, funktion och värde“. Thesis, Uppsala universitet, Textilvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-439775.

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Since the beginning of the early 20th century bed rugs have been interesting research objects, but only in passing researchers have paid attention to rugs woven with rags. Noone has taken a closer look upon the reasons why people have woven these rugs. What does the materials of the rag – like recycled garments and interior textiles in the form of clothing rags – have to tell about the times when these rugs were woven? Did the rag rugs have any specific function or were the materials available and therefore used? The main sources of information are 21 rag rugs from Roslagen in Uppland, with a varied amount of rags. They were woven during the latter half of 19th century, and estate inventories from Väddö- and Häverö Ship District have altogether given some answers to the primary question of this paper: in wich way can the examined bed rugs bear witness to the use and value of recycled textile materials and the view of these in the context of the community where they were manufactured and used? This research doesn´t give an answer to whether these rugs have any particular function or not. Instead these rag rugs can be looked upon as representing a general development of the society towards an increasing amount of textiles surplus material. This being due an increasing consumption of factory-made clothing and textiles, manufactured in factories, as well as the paper mills development from producing paper made of cellulose rather than textile waste. To this we can add a principle lingering on from the 19th century, of domestic production and a thrift of resources. This resulted in an obvious recycling of discarded textiles. The home weaving of interior textiles was still strong by the end of the 19th century, and in Rosagen there was also a long tradition of weaving and of using rugs in the beds. At the same time there was, in the coastal regions of Roslagen, a local need for warming covers in boats and boat houses. This demand was related to the shooting of seals and other hunting in the coastal areas, as well as in the fishing- and maritime trades.
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Yeshaya, Joachim J. M. S. „Moses ben Abraham Dari︠: a Karaite poet and physician from twelfth-century Egypt selective edition of the Dĩwãn on the basis of manuscript Firkovicz Heb. I 802, with introduction and commentary /“. [S.l. : s.n.], 2009. http://irs.ub/rug/nl/ppn/316.

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Rafat, Neysan. „The endothelium in sepsis: inflammatory response and progenitor cell involvement“. Groningen : [Groningen : Rijksuniversiteit Groningen ; University Library Groningen] [Host], 2009. http://irs.ub/rug/nl/pp/316.

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Nuernberger, Kathryn L. „Rag and Bone: Poems“. Ohio University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1312926732.

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Verkoczy, Laurent Karl. „Regulation studies of the human recombination activating genes, RAG-1 and RAG-2“. Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1995. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ51544.pdf.

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Silver, Daniel P. (Daniel Peter). „Studies of the structure and function of the RAG-1 and RAG-2 genes“. Thesis, Massachusetts Institute of Technology, 1992. http://hdl.handle.net/1721.1/12587.

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Corneo, Barbara. „Physiopathologie de la recombinaison v(d)j : structure et fonction des proteines rag1 et rag2“. Paris 5, 2001. http://www.theses.fr/2001PA05N025.

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Pike-Overzet, Karin. „Gene therapy for RAG-deficinet severe combined immunodeficiency“. [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10651.

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Fawell, Stuart Colin. „Polymorphism in the rag locus of porphyromonas gingivalis“. Thesis, Queen Mary, University of London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.412704.

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Bücher zum Thema "Rag rug"

1

Paula, Pfaff, Hrsg. Rag rug handbook. St. Paul, Minn: Dos Tejedoras Fiber Arts Publications, 1988.

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Meany, Janet. Rag rug handbook. Loveland, Colo., USA: Interweave Press, 1996.

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Fredlund, Jane. Rag rug weaves: Patterns from Sweden. Stockholm: LTS Forlag, 1986.

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A red stripe: Finnish American rag rug tradition and ethnic continuity. East Lansing, Mich: Michigan State University Press, 2009.

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Davies, Ann. Rag rugs. London: C. Letts, 1992.

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Bell, Lorraine. Rag rugs. [Derby]: Derbyshire College of Higher Education, 1987.

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Dhami, Mohanlal Chunilal. Rang rag virag. Rajkot: Navyug, 1987.

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Gryspeerdt, Mary. Somerset rag rugs. Glastonbury: Friends of the Abbey Barn, 1990.

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Tennant, Emma. Rag rugs of England and America. London: Walker Books, 1992.

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Haswell, Judith. From Finland. Newark, Vt: Janus Press, 1997.

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Buchteile zum Thema "Rag rug"

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Müller, Werner. „Rag Aktiengesellschaft“. In Deutsche Standards, 288–91. Wiesbaden: Gabler Verlag, 2005. http://dx.doi.org/10.1007/978-3-322-93425-3_70.

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Jewell, Jenna L., und Kun-Liang Guan. „Rag GTPases“. In Ras Superfamily Small G Proteins: Biology and Mechanisms 2, 277–92. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07761-1_12.

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Gooch, Jan W. „Tack Rag“. In Encyclopedic Dictionary of Polymers, 727. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_11517.

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Gooch, Jan W. „Rag Rolling“. In Encyclopedic Dictionary of Polymers, 607. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_9745.

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Lemke, Kono H., und Terry M. Seward. „2. Molecular Clusters and Solvation in Volcanic and Hydrothermal Vapors“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 57–84. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.02.

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King, Penelope L., Vincent M. Wheeler, Christian J. Renggli, Andrew B. Palm, Siobhan A. Wilson, Anna L. Harrison, Bree Morgan et al. „1. Gas–Solid Reactions: Theory, Experiments and Case Studies Relevant to Earth and Planetary Processes“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 1–56. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.1.

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Zolotov, Mikhail Yu. „10. Gas–Solid Interactions on Venus and Other Solar System Bodies“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 351–92. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.10.

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Sossi, Paolo A., und Bruce Fegley. „11. Thermodynamics of Element Volatility and its Application to Planetary Processes“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 393–460. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.11.

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Nagahara, Hiroko. „12. Kinetics of Gas–Solid Reactions in the Solar System and Beyond“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 461–98. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.12.

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Kreider, Peter, und Wojciech Lipiński. „13. High-Temperature Gas–Solid Reactions in Industrial Processes“. In High Temperature Gas-Solid Reactions in Earth and Planetary Processes, herausgegeben von Penelope King, Bruce Fegley und Terry Seward, 499–511. Berlin, Boston: De Gruyter, 2018. http://dx.doi.org/10.1515/rmg.2018.84.13.

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Konferenzberichte zum Thema "Rag rug"

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Rathmann, Ulrich, Sven Olmes und Alex Simeon. „Sealing Technology: Rub Test Rig for Abrasive/Abradable Systems“. In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-27724.

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Performance and efficiency optimization is one of the major tasks in the turbo machinery industry. Therefore efforts for scientific and technical improvements focus on optimization and reduction of losses. Secondary losses are of major interest because of their parasitic character related to stage efficiency and power output. One of these losses is over tip leakage of blades. Common practice is a minimization of this clearance with abrasive/abradable combinations. With this technique the blade tip (abrasive material) can rub into its counterpart (heat-shield, abradable material on casings or liners) and therefore minimize the operating tip-clearance. This technology is well established in compressor and turbine engineering since many years [1]. Field experience shows that abrasive/abradable systems do not always work as intended. In some cases rubbing conditions are reversed so that the intended abradable cuts into the abrasive. Any benefit on operating tip-clearance will then be minor at best or even negative. Rubbing behavior is difficult to predict, especially for new materials or geometries where no experience is available. In close cooperation with the University of Applied Sciences Rapperswil (Switzerland), ALSTOM has developed a test rig that allows simulating engine-operating conditions and therefore evaluate abrasive/abradable combinations before actual implementation into an engine. The rig is designed to reproduce circumferential velocities and incursion rates that are typical for gas turbine engines in the compressor as well as in the turbine. Forces and temperatures are measured as quantitative data, visual appearance and metallographic condition of test specimens are recorded as qualitative data that allow a more detailed assessment of material combinations and operating conditions. This paper describes the design of a high-speed wear rig facility to test single blade and fully shrouded rub configurations. In addition the validation of the test rig against real engine experience and knowledge is shown.
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Wang, Yaou, Chris Nault, Matthew Givens, Micah Threadgill, Seth Berry, Haitao Zhang und Ke Li. „Automation CAE Toolkit Method for Ram BOP Design“. In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-23769.

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Abstract A Blowout Preventer (BOP) serves as a safety valve in the drilling process in the oil and gas industry. It will be closed if an influx of formation fluids occurs and threatens the rig. A Ram BOP is one type of widely used BOP. It is composed of two ram blades, which will move towards each other to shear the drilling pipe and to close the valve. To ensure the shearing process be completed on the rig, lab tests are often run to evaluate the BOP’s capability and the required shearing pressure. The paper presents a new automation CAE (Computer-Aided Engineering) toolkit method recently developed to simulate the Ram BOP pipe shearing process. The toolkit method automates and integrates the process from computer aided design (CAD) to computer aided simulation for the Ram shearing process. It significantly simplifies the modeling effort and facilitates the design optimization process.
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Bai, Bo (Bob), Wei Chen, Khaled Ben Letaief und Zhigang Cao. „RBG matching“. In the 6th International Wireless Communications and Mobile Computing Conference. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1815396.1815540.

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4

Falah, Abdulazim H., Emad A. Khorshid und Khalid A. Alhazza. „Investigation of Rub-Impact Setup Supported on Flexible Multi-Bearing Rotor“. In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-86098.

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Vibration system investigation of the chaotic response of full annular rub impact rotor system supported on two ball bearings is investigated. Modeling and experiments of nonlinear dynamics on flexible multi-bearing rotor test rig is presented in this work. The test rig has two balancers that are assembled on rotor shaft, a rub impact device at the center, and ball bearings at both ends of the shaft. A 12-degree-of-freedom (DOF) linear model was developed for this test rig. The mathematical model was developed in the beginning without considering the rub impact part in order to validate the model with the experiment results. Then, then experimentally chaotic response and bifurcation diagram of the rub impact system were investigated.
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Burrus, D. L., A. W. Johnson, W. M. Roquemore und D. T. Shouse. „Performance Assessment of a Prototype Trapped Vortex Combustor Concept for Gas Turbine Application“. In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0087.

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GE Aircraft Engines and the Air Force Research Laboratory have been jointly developing a novel combustor technology concept for potential application in gas turbine engines. This novel combustor concept is known as the Trapped Vortex Combustor (TVC). The GE and AFRL team began work on the design of a prototypical TVC test rig in 1996. This effort represents the extension of earlier AFRL research with the TVC [1,2]. This work led to the fabrication of a 30.5 cm wide rectangular sector test rig capable of operation at inlet pressures up to 20.5 atmospheres, inlet temperatures up to 900 K, and to stoichiometric discharge conditions. Testing of the rectangular sector rig was initiated in mid year 1998. The performance evaluation performed on the test rig covered all aspects of gas turbine combustor performance and operability including ground start ignition, lean blowout, altitude re-light, emissions, combustion efficiency, exit gas temperature profile, and structural metal temperatures. Test rig operating conditions provided simulations of current commercial and military aircraft gas turbine engine cycles as well as some advanced engine cycles, with JP-8 type fuel. Data was also obtained at selected operating conditions for the LM2500 marine Navy duty cycle using DL-1 type fuel. The prototype rig has been operated for a total of approximately 300 run hours. 60 hours of run time at pressures exceeding 13.6 atmospheres and temperatures exceeding 675 K. 12 hours of run time at pressures exceeding 15.3 atmospheres, temperatures exceeding 780 K. Over 700 data points were obtained. The assessment of the demonstrated performance revealed the prototype TVC test rig had exceeded all initial expectations. Demonstrated ignition, blow out, and altitude re-light were up to 50% improved over current technology conventional swirl stabilized combustors. NOx emissions were in the range from 40% to 60% of the 1996 ICAO standard. Combustion efficiency at or above 99% was maintained over a 40% wider operating range than a conventional combustor. The performance and operability achieved with this prototype test rig has clearly demonstrated the validity and potential performance payoffs of the TVC concept. This paper will summarize the TVC rectangular sector test rig configurations evaluated as part of this test program, and the performance and operability achieved.
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Childs, Peter, Klaus Dullenkopf und Dieter Bohn. „Internal Air Systems Experimental Rig Best Practice“. In ASME Turbo Expo 2006: Power for Land, Sea, and Air. ASMEDC, 2006. http://dx.doi.org/10.1115/gt2006-90215.

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This paper reports best practice principles for experimental rig design and operation arising from a European Commision funded programme of research on internal air systems. The Internal Cooling Air Systems for Gas Turbines 2 (ICAS-GT2) research programme, ran from April 2001 to June 2005, and was undertaken by a consortium of ten gas turbine manufacturing companies and four universities. The programme of research involved both design and operation of a series of high pressure, high speed rotating rigs in order to deliver data at or near engine representative conditions. The rigs concerned cover the pre-swirl system, turbine rim seals, turbine stator wells, compressor rotor-rotor disc cavities, bolt windage and real engine parts experiments. Operation of these rigs has presented a wide range of challenges, particularly with respect to optical access in rotor-rotor and rotor-stator disc cavities and measurement of disc heat transfer. This paper explores the best practice principles developed for internal air system experimental rig design, operation and associated instrumentation.
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Van Aken, Peter, Cris DeWitt und Pat Slagle. „Applying Structure and Discipline to Rig Technology“. In ASME 2012 31st International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/omae2012-84171.

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The maritime and offshore industries are increasingly reliant on integrated computer-based control systems and the associated software that actually ‘runs’ the systems. Industrial computers and the software they run are controlling exponentially more rig functions than ever before with increasingly more complex coding for expanded functionality. Ultimately, introduction of these complex systems into safety, environmental and operational functions have a significant impact on rig performance—software quality management is becoming a primary contributor to the overall performance of a rig.
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de Groot, Philip G., Jan A. van Mourik und Jan J. Sixma. „PRIMARY BINDING SITE OF VON WILLEBRAND FACTOR IN THE SUBENDOTHELIUM WHICH MEDIATES PLATELET ADHESION IS NOT COLLAGEN“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643587.

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We have studies the binding of von Willebrand factor (vWF) to extracellular matrices of endothelial cells and smooth muscle cells and to the vessel wall of human umbilical arteries in relation to its function in supporting platelet adhesion at high shear rates. CLB-RAg 38, a monoclonal antibody directed against vWF inhibits the binding of 125I-vWF extracellular matrices completely. The binding of 125I-vWF to subendothelium is not inhibited, because there are many different binding sites. CLB-RAg 38 inhibits platelet adhesion to extracellular matrices and subendothelium, in sofar as it is dependent on plasma vWF. CLB-RAg 38 has no effect on adhesion depending on vWF already bound to the matrix or subendothelium. CLB-RAg 38 does not inhibit binding of vWF to collagen type I and type III. Another monoclonal antibody against vWF, CLB-RAg 201, completely inhibits binding of vWF to collagen type I and type III. CLB-RAg 201 does not inhibit binding of 125I-vWF ot the extracellular matrices. CLB-RAg 201 partly inhibits platelet adhesion but this inhibition is also present when the adhesion depends on vWF already present in matrix or subendothelium, indicating that CLB-RAg 201 also inhibits the adhesion of platelets directly, this in contrast to CLB-RAg 38. The epitopes for CLB-RAg 201 and 38 were found on different tryptic fragments of vWF. These data indicate that vWF binds to subendothelium and to matrices of cultured cells by mechanism that is different from binding to collagen.
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Lindman, Olle, Mats Andersson, Alessio Bonaldo, Anders Larsson, Jacek Janczewski und Magnus Persson. „SGT-750 Fuel Flexibility: Engine and Rig Tests“. In ASME Turbo Expo 2017: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/gt2017-63412.

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This paper provides a description of the fuel flexibility tests performed in: • a gas turbine • a high pressure combustion rig • an atmospheric combustion rig with the combustion system used in Siemens recently developed gas turbine SGT-750. The gas turbine test campaign was run with natural gas blends with up to 50vol% nitrogen or 40vol% carbon dioxide. Ignition and engine starts with inert gas blends were also tested. The fuel flexibility tests were continued in a single burner high pressure combustion rig. Both inert and reactive gas blends were tested. High concentrations of inert gases were tested at simulated cold ambient conditions (down to −60°C) at high and low loads. Reactive gases, such as ethane, propane, butane and hydrogen, were tested at high load operation. Also syngas blends were tested. To simulate ignition at extreme arctic conditions an atmospheric rig test was performed with cold air supplied from evaporated liquid air. The different gas fuel blends were run with low NOx emissions, often below 10 ppm, without water injection. This paper includes description of the test setups and evaluation of the emissions and combustion stability for the tested gas blends.
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Chan, B. J., und Corina Sandu. „Development of a Virtual 7-Post Test Rig for Experimental Validation“. In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-13971.

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A seven-post test rig is an experimental device that allows the simulation/recreation of driving conditions (e.g., racing track conditions) in the controlled environment of the laboratory. In general, the vehicle models used for tuning the real vehicle are very simplified. This may lead to differences between the results obtained using the computer model and the actual vehicle behavior as measured when mounted on the seven post test rig. This paper presents an effort to create a virtual seven post model to analyze the difference between the actual laboratory tests and the virtual model with the simplified vehicle models. A simplified full-car model is mounted on the virtual seven post rig with the ideal road input and the ideal parameters. Data from the simulation is meant to be compared with the actual experimental data from the rig to provide insight into tuning the suspension of the vehicle to optimize the tire force generation and vehicle handling. Moreover, a virtual seven post rig will allow researchers to run simulations of tuned vehicles or develop control policies for suspension system prior to performing the tests on the actual rig. The virtual rig will actually save development time and eliminate dangerous scenarios, and reduce the possibility of damaging the rig.
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Berichte der Organisationen zum Thema "Rag rug"

1

Ramey, Garey, und Valerie Ramey. The Rug Rat Race. Cambridge, MA: National Bureau of Economic Research, August 2009. http://dx.doi.org/10.3386/w15284.

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2

Meyer, William R. Rocket Propelled Grenade (RPG), RPG-7VM, MIL-STD-1660 Tests. Fort Belvoir, VA: Defense Technical Information Center, August 1995. http://dx.doi.org/10.21236/ada391649.

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3

Schock, Alfred. Mars Rover RTG Study. Office of Scientific and Technical Information (OSTI), Oktober 1989. http://dx.doi.org/10.2172/1033348.

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4

Schock, Alfred. Mars Rover RTG Study. Office of Scientific and Technical Information (OSTI), November 1989. http://dx.doi.org/10.2172/1033388.

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5

Schock, Alfred. Mars Rover RTG Study. Office of Scientific and Technical Information (OSTI), August 1989. http://dx.doi.org/10.2172/1033423.

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6

Boone, S. G. TRU VU rig instrumentation. Office of Scientific and Technical Information (OSTI), Februar 1993. http://dx.doi.org/10.2172/6745935.

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7

Kelly, C. E., und P. M. Klee. Cassini RTG acceptance test results and RTG performance on Galileo and Ulysses. Office of Scientific and Technical Information (OSTI), Juni 1997. http://dx.doi.org/10.2172/481894.

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8

Olds, Daniel P. CAD drawing of tensile rig. Office of Scientific and Technical Information (OSTI), Juni 2014. http://dx.doi.org/10.2172/1134794.

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9

Mulford, Roberta Nancy. Radioisotopic Thermoelectric Generator (RTG) Surveillance. Office of Scientific and Technical Information (OSTI), September 2016. http://dx.doi.org/10.2172/1329647.

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10

Owsley, Stanley L., Michael G. Dodson, Brian K. Hatchell, Thomas A. Seim, David L. Alexander und Woodrow T. Hawthorne. RSG Deployment Case Testing Results. Office of Scientific and Technical Information (OSTI), September 2005. http://dx.doi.org/10.2172/1037547.

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