Zeitschriftenartikel zum Thema „Picropodophylline“
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Roulland, Emmanuel, Emmanuel Bertounesque, Christiane Huel und Claude Monneret. „Synthesis of picropodophyllin homolactone“. Tetrahedron Letters 41, Nr. 35 (August 2000): 6769–73. http://dx.doi.org/10.1016/s0040-4039(00)01136-9.
Der volle Inhalt der QuelleRoulland, Emmanuel, Emmanuel Bertounesque, Christiane Huel und Claude Monneret. „ChemInform Abstract: Synthesis of Picropodophyllin Homolactone.“ ChemInform 31, Nr. 45 (07.11.2000): no. http://dx.doi.org/10.1002/chin.200045231.
Der volle Inhalt der QuelleWen, Pu Hong. „Kinetic Investigation of Thermal Decomposition Reactions of Podophyllic Acid and Picropodophyllic Acid“. Advanced Materials Research 391-392 (Dezember 2011): 1230–34. http://dx.doi.org/10.4028/www.scientific.net/amr.391-392.1230.
Der volle Inhalt der QuelleGuo, Hong Zhu, De An Guo, Xue Yan Fei, Ya Jun Cui und Jun Hua Zheng. „Biotransformation of Podophyllotoxin to Picropodophyllin by Microbes“. Journal of Asian Natural Products Research 1, Nr. 2 (Dezember 1998): 99–102. http://dx.doi.org/10.1080/10286029808039850.
Der volle Inhalt der QuelleOhshima-Hosoyama, Sachiko, Tohru Hosoyama, Laura D. Nelon und Charles Keller. „IGF-1 receptor inhibition by picropodophyllin in medulloblastoma“. Biochemical and Biophysical Research Communications 399, Nr. 4 (September 2010): 727–32. http://dx.doi.org/10.1016/j.bbrc.2010.08.009.
Der volle Inhalt der QuelleWu, Qi, Ai-Ling Tian, Guido Kroemer und Oliver Kepp. „Autophagy induction by IGF1R inhibition with picropodophyllin and linsitinib“. Autophagy 17, Nr. 8 (10.06.2021): 2046–47. http://dx.doi.org/10.1080/15548627.2021.1936934.
Der volle Inhalt der QuelleBerkowitz, David B., Sungjo Choi und Jun-Ho Maeng. „Enzyme-Assisted Asymmetric Total Synthesis of (−)-Podophyllotoxin and (−)-Picropodophyllin“. Journal of Organic Chemistry 65, Nr. 3 (Februar 2000): 847–60. http://dx.doi.org/10.1021/jo991582+.
Der volle Inhalt der QuellePohmakotr, Manat, Taweechote Komutkul, Patoomratana Tuchinda, Samrarn Prabpai, Palangpon Kongsaeree und Vichai Reutrakul. „Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone“. Tetrahedron 61, Nr. 22 (Mai 2005): 5311–21. http://dx.doi.org/10.1016/j.tet.2005.03.069.
Der volle Inhalt der QuellePullin, Robert D. C., Jonathan D. Sellars und Patrick G. Steel. „Silenes in organic synthesis: a concise synthesis of (±)-epi-picropodophyllin“. Organic & Biomolecular Chemistry 5, Nr. 19 (2007): 3201. http://dx.doi.org/10.1039/b710370k.
Der volle Inhalt der QuelleColón, Eugenia, Farasat Zaman, Magnus Axelson, Olle Larsson, Christine Carlsson-Skwirut, Konstantin V. Svechnikov und Olle Söder. „Insulin-Like Growth Factor-I Is an Important Antiapoptotic Factor for Rat Leydig Cells during Postnatal Development“. Endocrinology 148, Nr. 1 (01.01.2007): 128–39. http://dx.doi.org/10.1210/en.2006-0835.
Der volle Inhalt der QuelleZhao, Jing, Yajing Wang und Libiao Luan. „Star-Shaped Polycaprolactone-Polyethyleneglycol Copolymer Micelle-Like Nanoparticles for Picropodophyllin Delivery“. Journal of Biomedical Nanotechnology 10, Nr. 8 (01.08.2014): 1627–34. http://dx.doi.org/10.1166/jbn.2014.1835.
Der volle Inhalt der QuelleHashemi, Jamileh, Claire Worrall, Daiana Vasilcanu, Mårten Fryknäs, Luqman Sulaiman, Mohsen Karimi, Wen-Hui Weng et al. „Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)“. PLoS ONE 6, Nr. 3 (14.03.2011): e14757. http://dx.doi.org/10.1371/journal.pone.0014757.
Der volle Inhalt der QuelleLu, Xiaosheng, Ledan Wang, Jie Mei, Xin Wang, Xueqiong Zhu, Qiong Zhang und Jieqiang Lv. „Picropodophyllin inhibits epithelial ovarian cancer cells in vitro and in vivo“. Biochemical and Biophysical Research Communications 435, Nr. 3 (Juni 2013): 385–90. http://dx.doi.org/10.1016/j.bbrc.2013.04.097.
Der volle Inhalt der QuelleBerkowitz, David B., Sungjo Choi und Jun-Ho Maeng. „ChemInform Abstract: Enzyme-Assisted Asymmetric Total Synthesis of (-)-Podophyllotoxin and (-)-Picropodophyllin.“ ChemInform 31, Nr. 23 (08.06.2010): no. http://dx.doi.org/10.1002/chin.200023243.
Der volle Inhalt der QuelleFENG, XIAOYING, EIMAN ALEEM, YINGBO LIN, MAGNUS AXELSON, OLLE LARSSON und THOMAS STRÖMBERG. „Multiple antitumor effects of picropodophyllin in colon carcinoma cell lines: Clinical implications“. International Journal of Oncology 40, Nr. 4 (06.12.2011): 1251–58. http://dx.doi.org/10.3892/ijo.2011.1281.
Der volle Inhalt der QuelleWu, Xuping, Linda Sooman, Malin Wickström, Mårten Fryknäs, Christine Dyrager, Johan Lennartsson und Joachim Gullbo. „Alternative Cytotoxic Effects of the Postulated IGF-IR Inhibitor Picropodophyllin In Vitro“. Molecular Cancer Therapeutics 12, Nr. 8 (22.05.2013): 1526–36. http://dx.doi.org/10.1158/1535-7163.mct-13-0091.
Der volle Inhalt der QuelleYin, Shu-Cheng, Wei Guo und Ze-Zhang Tao. „Picropodophyllin inhibits tumor growth of human nasopharyngeal carcinoma in a mouse model“. Biochemical and Biophysical Research Communications 439, Nr. 1 (September 2013): 1–5. http://dx.doi.org/10.1016/j.bbrc.2013.08.050.
Der volle Inhalt der QuelleVitale, Maxime, Guillaume Prestat, David Lopes, David Madec, Claire Kammerer, Giovanni Poli und Leonard Girnita. „New Picropodophyllin Analogs via Palladium-Catalyzed Allylic Alkylation−Hiyama Cross-Coupling Sequences“. Journal of Organic Chemistry 73, Nr. 15 (August 2008): 5795–805. http://dx.doi.org/10.1021/jo800707q.
Der volle Inhalt der QuelleOgiku, Tsuyoshi, Shin-ichi Yoshida, Tooru Kuroda, Masami Takahashi, Hiroshi Ohmizu und Tameo Iwasaki. „Syntheses of Aryltetralin Lignans: Concise Syntheses of (±)-Isopodophyllotoxone, (±)-Picropodophyllone and Their Related Compounds“. Bulletin of the Chemical Society of Japan 65, Nr. 12 (Dezember 1992): 3495–97. http://dx.doi.org/10.1246/bcsj.65.3495.
Der volle Inhalt der QuelleTOMIZAWA, MINORU, FUMINOBU SHINOZAKI, YASUFUMI MOTOYOSHI, TAKAO SUGIYAMA, SHIGENORI YAMAMOTO und MAKOTO SUEISHI. „Picropodophyllin and sorafenib synergistically suppress the proliferation and motility of hepatocellular carcinoma cells“. Oncology Letters 8, Nr. 5 (27.08.2014): 2023–26. http://dx.doi.org/10.3892/ol.2014.2484.
Der volle Inhalt der QuelleOGIKU, T., S. YOSHIDA, T. KURODA, M. TAKAHASHI, H. OHMIZU und T. IWASAKI. „ChemInform Abstract: Syntheses of Aryltetralin Lignans: Concise Syntheses of (.+-.)- Isopodophyllotoxone, (.+-.)-Picropodophyllone and Related Compounds.“ ChemInform 24, Nr. 15 (20.08.2010): no. http://dx.doi.org/10.1002/chin.199315280.
Der volle Inhalt der QuelleWong Te Fong, Anne-Christine, Thomas R. Eykyn, Harry G. Parkes, Aleksandra Bielen, Chris Jones, Ian R. Judson, John R. Griffiths, Martin O. Leach und Yuen-Li Chung. „Abstract B61: Picropodophyllin (PPP) increases glucose metabolism and lactate production in paediatric glioblastoma cells“. Clinical Cancer Research 18, Nr. 10 Supplement (15.05.2012): B61. http://dx.doi.org/10.1158/1078-0432.mechres-b61.
Der volle Inhalt der QuelleMeresse, Philippe, Claude Monneret und Emmanuel Bertounesque. „Synthesis of podophyllotoxin analogues: δ-lactone-containing picropodophyllin, podophyllotoxin and 4′-demethyl-epipodophyllotoxin derivatives“. Tetrahedron 60, Nr. 11 (März 2004): 2657–71. http://dx.doi.org/10.1016/j.tet.2004.01.017.
Der volle Inhalt der QuelleLemaire, Miguel, Charlotte Fristedt, Prasoon Agarwal, Eline Menu, Els Van Valckenborgh, Elke De Bruyne, Anders Österborg et al. „The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor Picropodophyllin“. Clinical Cancer Research 18, Nr. 8 (05.03.2012): 2230–39. http://dx.doi.org/10.1158/1078-0432.ccr-11-1764.
Der volle Inhalt der QuelleZhang, Qi, Jing Pan, Ronald A. Lubet, Yian Wang und Ming You. „Targeting the insulin-like growth factor-1 receptor by picropodophyllin for lung cancer chemoprevention“. Molecular Carcinogenesis 54, S1 (27.08.2014): E129—E137. http://dx.doi.org/10.1002/mc.22206.
Der volle Inhalt der QuelleBieghs, Liesbeth, Susanne Lub, Karel Fostier, Ken Maes, Els Van Valckenborgh, Eline Menu, Hans E. Johnsen et al. „The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic“. Oncotarget 5, Nr. 22 (30.04.2014): 11193–208. http://dx.doi.org/10.18632/oncotarget.1933.
Der volle Inhalt der QuelleDong, Lin, Meirong Du und Qianzhou Lv. „Picropodophyllin inhibits type I endometrial cancer cell proliferation via disruption of the PI3K/Akt pathway“. Acta Biochimica et Biophysica Sinica 51, Nr. 7 (06.06.2019): 753–60. http://dx.doi.org/10.1093/abbs/gmz055.
Der volle Inhalt der QuelleYoshida, Shin-ichi, Takeshi Yamanaka, Tutomu Miyake, Yasunori Moritani, Hiroshi Ohmizu und Tameo Iwasaki. „Asymmetric syntheses of lignans utilizing novel diastereoselective Michael addition of cyanohydrin: Syntheses of (+)-fargesin and (−)-picropodophyllone“. Tetrahedron 53, Nr. 28 (Juli 1997): 9585–98. http://dx.doi.org/10.1016/s0040-4020(97)00643-1.
Der volle Inhalt der QuelleYin, S., A. Girnita, T. Stromberg, Z. Khan, S. Andersson, H. Zheng, C. Ericsson et al. „Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma“. Neuro-Oncology 12, Nr. 1 (20.10.2009): 19–27. http://dx.doi.org/10.1093/neuonc/nop008.
Der volle Inhalt der QuelleYOSHIDA, S., T. YAMANAKA, T. MIYAKE, Y. MORITANI, H. OHMIZU und T. IWASAKI. „ChemInform Abstract: Asymmetric Syntheses of Lignans Utilizing Novel Diastereoselective Michael Addition of Cyanohydrin: Syntheses of (+)-Fargesin and (-)- Picropodophyllone.“ ChemInform 28, Nr. 50 (02.08.2010): no. http://dx.doi.org/10.1002/chin.199750276.
Der volle Inhalt der QuelleWaraky, Ahmed, Karen Akopyan, Vendela Parrow, Thomas Strömberg, Magnus Axelson, Lars Abrahmsén, Arne Lindqvist, Olle Larsson und Eiman Aleem. „Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via Insulin-like growth factor-1 receptor-independent mechanism“. Oncotarget 5, Nr. 18 (31.07.2014): 8379–92. http://dx.doi.org/10.18632/oncotarget.2292.
Der volle Inhalt der QuelleEconomou, Mario A., Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard und Olle Larsson. „Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma“. Investigative Opthalmology & Visual Science 49, Nr. 6 (01.06.2008): 2337. http://dx.doi.org/10.1167/iovs.07-0819.
Der volle Inhalt der QuelleEconomou, Mario A., Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard und Olle Larsson. „Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma“. Acta Ophthalmologica 86, esis4 (19.11.2008): 35–41. http://dx.doi.org/10.1111/j.1755-3768.2008.01184.x.
Der volle Inhalt der QuelleJiang, Li-hua, Nian-yun Yang, Xiao-lin Yuan, Yi-jie Zou, Ze-qun Jiang, Feng-ming Zhao, Jian-ping Chen, Ming-yan Wang und Da-xiang Lu. „Microarray Analysis of mRNA and MicroRNA Expression Profile Reveals the Role ofβ-Sitosterol-D-glucoside in the Proliferation of Neural Stem Cell“. Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–12. http://dx.doi.org/10.1155/2013/360302.
Der volle Inhalt der QuelleConti, Laura, Gabriella Regis, Angela Longo, Paola Bernabei, Roberto Chiarle, Mirella Giovarelli und Francesco Novelli. „In the absence of IGF-1 signaling, IFN-γ suppresses human malignant T-cell growth“. Blood 109, Nr. 6 (05.12.2006): 2496–504. http://dx.doi.org/10.1182/blood-2006-07-034231.
Der volle Inhalt der QuelleGong, Wan, Naidan Zhang, Gang Cheng, Quanlong Zhang, Yuqiong He, Yi Shen, Qi Zhang, Bo Zhu, Qiaoyan Zhang und Luping Qin. „Rehmannia glutinosa Libosch Extracts Prevent Bone Loss and Architectural Deterioration and Enhance Osteoblastic Bone Formation by Regulating the IGF-1/PI3K/mTOR Pathway in Streptozotocin-Induced Diabetic Rats“. International Journal of Molecular Sciences 20, Nr. 16 (15.08.2019): 3964. http://dx.doi.org/10.3390/ijms20163964.
Der volle Inhalt der QuelleWU, YONG-TAO, BAO-JUN WANG, SHENG-WU MIAO und JIAN-JUN GAO. „Picropodophyllin inhibits the growth of Ewing's sarcoma cells through the insulin-like growth factor-1 receptor/Akt signaling pathway“. Molecular Medicine Reports 12, Nr. 5 (28.08.2015): 7045–50. http://dx.doi.org/10.3892/mmr.2015.4266.
Der volle Inhalt der QuelleLiao, Fenfang, Yongheng Chen, Qingqing Wu, Jiaqi Wen, Xiangjie Chen, Weizhang Wang, Dan Xu und Manyu Liu. „Selective elimination of CML stem/progenitor cells by picropodophyllin in vitro and in vivo is associated with p53 activation“. Biochemical and Biophysical Research Communications 579 (November 2021): 1–7. http://dx.doi.org/10.1016/j.bbrc.2021.09.029.
Der volle Inhalt der QuelleVasilcanu, R., D. Vasilcanu, L. Rosengren, N. Natalishvili, B. Sehat, S. Yin, A. Girnita, M. Axelson, L. Girnita und O. Larsson. „Picropodophyllin induces downregulation of the insulin-like growth factor 1 receptor: potential mechanistic involvement of Mdm2 and β-arrestin1“. Oncogene 27, Nr. 11 (10.09.2007): 1629–38. http://dx.doi.org/10.1038/sj.onc.1210797.
Der volle Inhalt der QuelleMo, Hai-Ying, Qi-Yao Wei, Qiu-Hua Zhong, Xiao-Yun Zhao, Dan Guo, Jin Han, Wachiraporn Noracharttiyapot et al. „Cytochrome P450 27C1 Level Dictates Lung Cancer Tumorigenicity and Sensitivity towards Multiple Anticancer Agents and Its Potential Interplay with the IGF-1R/Akt/p53 Signaling Pathway“. International Journal of Molecular Sciences 23, Nr. 14 (16.07.2022): 7853. http://dx.doi.org/10.3390/ijms23147853.
Der volle Inhalt der QuelleMenu, Eline, Helena Jernberg-Wiklund, Thomas Stromberg, Hendrik De Raeve, Leonard Girnita, Olle Larsson, Magnus Axelson et al. „Inhibiting the IGF-1 receptor tyrosine kinase with the cyclolignan PPP: an in vitro and in vivo study in the 5T33MM mouse model“. Blood 107, Nr. 2 (15.01.2006): 655–60. http://dx.doi.org/10.1182/blood-2005-01-0293.
Der volle Inhalt der QuelleTakata, Sho, Hiromi Sakata-Haga, Hiroki Shimada, Tsuyoshi Tsukada, Daisuke Sakai, Hiroki Shoji, Mitsuhiro Tomosugi et al. „LIF–IGF Axis Contributes to the Proliferation of Neural Progenitor Cells in Developing Rat Cerebrum“. International Journal of Molecular Sciences 23, Nr. 21 (30.10.2022): 13199. http://dx.doi.org/10.3390/ijms232113199.
Der volle Inhalt der QuelleRazuvaev, Anton, Bimma Henderson, Leonard Girnita, Olle Larsson, Magnus Axelson, Ulf Hedin und Joy Roy. „The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling“. Journal of Vascular Surgery 46, Nr. 1 (Juli 2007): 108–15. http://dx.doi.org/10.1016/j.jvs.2007.02.066.
Der volle Inhalt der QuelleWu, Qi, Ai-Ling Tian, Bei Li, Marion Leduc, Sabrina Forveille, Peter Hamley, Warren Galloway et al. „IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms−“. Journal for ImmunoTherapy of Cancer 9, Nr. 6 (Juni 2021): e002722. http://dx.doi.org/10.1136/jitc-2021-002722.
Der volle Inhalt der QuelleEconomou, Mario A., Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg van der Ploeg, Eline Menu et al. „Inhibition of VEGF Secretion and Experimental Choroidal Neovascularization by Picropodophyllin (PPP), an Inhibitor of the Insulin-like Growth Factor-1 Receptor“. Investigative Opthalmology & Visual Science 49, Nr. 6 (01.06.2008): 2620. http://dx.doi.org/10.1167/iovs.07-0742.
Der volle Inhalt der QuelleEconomou, Mario A., Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg Van Der Ploeg, Eline Menu et al. „Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor“. Acta Ophthalmologica 86, esis4 (19.11.2008): 42–49. http://dx.doi.org/10.1111/j.1755-3768.2008.01185.x.
Der volle Inhalt der QuelleE, Changyong, Jing Li, Dan Shao, Dan Zhang, Yue Pan, Li Chen und Xuewen Zhang. „The Insulin-Like Growth Factor-I Receptor Inhibitor Picropodophyllin-Induced Selective Apoptosis of Hepatocellular Carcinoma Cell Through a Caspase-Dependent Mitochondrial Pathway“. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 21, Nr. 2 (10.01.2014): 103–10. http://dx.doi.org/10.3727/096504013x13808175127324.
Der volle Inhalt der QuelleGirnita, Ada, Charlotta All-Ericsson, Mario A. Economou, Kristina Astr√∂m, Magnus Axelson, Stefan Seregard, Olle Larsson und Leonard Girnita. „The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells.“ Clinical Cancer Research 12, Nr. 4 (15.02.2006): 1383–91. http://dx.doi.org/10.1158/1078-0432.ccr-05-1106.
Der volle Inhalt der QuelleDuan, Zhenfeng, Edwin Choy, David Harmon, Cao Yang, Keinosuke Ryu, Joseph Schwab, Henry Mankin und Francis J. Hornicek. „Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines“. Molecular Cancer Therapeutics 8, Nr. 8 (28.07.2009): 2122–30. http://dx.doi.org/10.1158/1535-7163.mct-09-0115.
Der volle Inhalt der QuelleGullbo, Joachim, Michael Bergqvist, Malin Wickström, Peter Ericsson, Linda Sooman, Daniel Brattström, Stefan Bergström und Simon Ekman. „P3-016: In vitro activity of picropodophyllin in lung cancer cell lines and association to the insulin-like Growth Factor-1 receptor“. Journal of Thoracic Oncology 2, Nr. 8 (August 2007): S613—S614. http://dx.doi.org/10.1097/01.jto.0000283773.72586.f8.
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