Thematische Bibliographien / Phage MDA

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „Phage MDA“

Autor: Grafiati
Veröffentlicht am 12. April 2025

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Zeitschriftenartikel zum Thema "Phage MDA"

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Dymova, Maya Alexandrovna, Yaroslav Alexandrovich Utkin, Maria Denisovna Dmitrieva, Elena Vladimirovna Kuligina, and Vladimir Alexandrovich Richter. "Modification of a Tumor-Targeting Bacteriophage for Potential Diagnostic Applications." Molecules 26, no. 21 (2021): 6564. http://dx.doi.org/10.3390/molecules26216564.

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Background: Tumor-targeting bacteriophages can be used as a versatile new platform for the delivery of diagnostic imaging agents and therapeutic cargo. This became possible due to the development of viral capsid modification method. Earlier in our laboratory and using phage display technology, phages to malignant breast cancer cells MDA-MB 231 were obtained. The goal of this study was the optimization of phage modification and the assessment of the effect of the latter on the efficiency of phage particle penetration into MDA-MB 231 cells. Methods: In this work, we used several methods, such as
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Brown, D. J., E. J. Threlfall, M. D. Hampton, and B. Rowe. "Molecular characterization of plasmids in Salmonella enteritidis phage types." Epidemiology and Infection 110, no. 2 (1993): 209–16. http://dx.doi.org/10.1017/s0950268800068126.

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SUMMARYPlasmids in selected type strains of 26 of the Salmonella enteritidis phage types have been characterized by restriction enzyme fingerprinting and by DNA–DNA hybridization with oligonucleotide probes for Salmonella plasmid virulence (Spv) genes. With one exception, the fingerprints of the 38 MDa plasmids studied were homogeneous but there was heterogeneity in the fingerprints of 59 MDa plasmids found in 4 of the type strains. However all 38 MDa and 59 MDa plasmids were related as was a 45 MDa plasmid identified in the type strain of phage type 19. A 3·5 kb fragment homologous to SpvC wa
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van Passel, Mark W. J., Arie van der Ende, and Aldert Bart. "Plasmid Diversity in Neisseriae." Infection and Immunity 74, no. 8 (2006): 4892–99. http://dx.doi.org/10.1128/iai.02087-05.

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ABSTRACT Horizontal gene transfer constitutes an important force in prokaryotic genome evolution, and it is well-known that plasmids are vehicles for DNA transfer. Chromosomal DNA is frequently exchanged between pathogenic and commensal neisseriae, but relatively little is known about plasmid diversity and prevalence among these nasopharyngeal inhabitants. We investigated the plasmid contents of 18 Neisseria lactamica isolates and 20 nasopharyngeal Neisseria meningitidis isolates. Of 18 N. lactamica strains, 9 harbored one or more plasmids, whereas only one N. meningitidis isolate contained a
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Kozarsky, Phyllis E., David Rimland, Pamela M. Terry, and Kaye Wachsmuth. "Plasmid Analysis of Simultaneous Nosocomial Outbreaks of Methicillin-Resistant Staphylococcus aureus." Infection Control 7, no. 12 (1986): 577–81. http://dx.doi.org/10.1017/s0195941700065413.

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AbstractA large outbreak of infections caused by methicillin and aminoglycoside resistant Staphylococcus aureus provided the opportunity to evaluate mechanisms of resistance and compare the usefulness of typing systems. Between January 1979 and December 1980, 63 patients developed infections with S aureus resistant to multiple antibiotics, including methicillin and tobramycin. All isolates had an identical antibiogram and were phage type 47/54/75/77/83A. Beginning in January 1981, a superimposed outbreak caused by S aureus of the same phage type but with a resistance pattern now including gent
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Pertics, Botond Zsombor, Tamás Kovács, and György Schneider. "Characterization of a Lytic Bacteriophage and Demonstration of Its Combined Lytic Effect with a K2 Depolymerase on the Hypervirulent Klebsiella pneumoniae Strain 52145." Microorganisms 11, no. 3 (2023): 669. http://dx.doi.org/10.3390/microorganisms11030669.

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Klebsiella pneumoniae is a nosocomial pathogen. Among its virulence factors is the capsule with a prominent role in defense and biofilm formation. Bacteriophages (phages) can evoke the lysis of bacterial cells. Due to the mode of action of their polysaccharide depolymerase enzymes, phages are typically specific for one bacterial strain and its capsule type. In this study, we characterized a bacteriophage against the capsule-defective mutant of the nosocomial K. pneumoniae 52145 strain, which lacks K2 capsule. The phage showed a relatively narrow host range but evoked lysis on a few strains wit
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Tonin, Patricia N., and Robert B. Grant. "Genetic and physical characterization of trimethoprim resistance plasmids from Shigella sonnei and Shigella flexneri." Canadian Journal of Microbiology 33, no. 10 (1987): 905–13. http://dx.doi.org/10.1139/m87-157.

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Analysis of six Shigella flexneri and four S. sonnei isolates with trimethoprim (Tp) resistance from clinical cases in Ontario has shown that, in all isolates, the Tp resistance is mediated by gene(s) on conjugative, multiple antibiotic-resistance plasmids. The physical and genetic characterization of these plasmids revealed that there are three different Tp resistance plasmids. One group, composed of all six S. flexneri plasmids, consists of plasmids which are about 70 megadaltons (MDa) and inhibit the fertility of an Escherichia coli Hfr strain (Fi+). A representative member of this group, p
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Petrenko, Valery A., James W. Gillespie, Hai Xu, Tiffany O’Dell, and Laura M. De Plano. "Combinatorial Avidity Selection of Mosaic Landscape Phages Targeted at Breast Cancer Cells—An Alternative Mechanism of Directed Molecular Evolution." Viruses 11, no. 9 (2019): 785. http://dx.doi.org/10.3390/v11090785.

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Low performance of actively targeted nanomedicines required revision of the traditional drug targeting paradigm and stimulated the development of novel phage-programmed, self-navigating drug delivery vehicles. In the proposed smart vehicles, targeting peptides, selected from phage libraries using traditional principles of affinity selection, are substituted for phage proteins discovered through combinatorial avidity selection. Here, we substantiate the potential of combinatorial avidity selection using landscape phage in the discovery of Short Linear Motifs (SLiMs) and their partner domains. W
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Binkin, N., G. Scuderi, F. Novaco, et al. "Egg-relatedSalmonella enteritidis, Italy, 1991." Epidemiology and Infection 110, no. 2 (1993): 227–37. http://dx.doi.org/10.1017/s095026880006814x.

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SUMMARYIn recent years,Salmonella enteritidishas become an increasingly important public health problem in Italy. In some parts of the country, the fraction of total human salmonella isolates accounted for byS. enteritidishas risen from 3–4% in the mid-1980s to more than 30% in 1990. Between 1090 and 1991. the number of reportedS. enteritidisoutbreaks increased more than sixfold. The 33 outbreaks reported in 1991 occurred in seven contiguous regions in northern and central Italy and were clustered in time between June and October: in the majority, products containing raw or undercooked shell e
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Harnett, N., S. McLeod, Y. AuYong, et al. "Molecular characterization of multiresistant strains ofSalmonella typhifrom South Asia isolated in Ontario, Canada." Canadian Journal of Microbiology 44, no. 4 (1998): 356–63. http://dx.doi.org/10.1139/w98-012.

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Two hundred and fourteen isolates of Salmonella typhi submitted to our laboratory between 1992 and 1996 were tested for susceptibility to 20 antimicrobial agents. Forty-eight of the 214 isolates (22.4%), recovered from individuals who had travelled in South Asia, were multiresistant. Forty-four of the 48 isolates were resistant to ampicillin, chloramphenicol, tetracycline, streptomycin, sulfamethoxazole, trimethoprim, cotrimoxazole, ticarcillin, and piperacillin; the other four isolates were resistant to four to six agents. Forty-two of the multiresistant isolates belonged to Vi phage type E1,
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Stanley, J., A. P. Burnens, E. J. Threlfall, N. Chowdry, and M. Goldsworthy. "Genetic relationships among strains ofSalmonella enteritidisin a national epidemic in Switzerland." Epidemiology and Infection 108, no. 2 (1992): 213–20. http://dx.doi.org/10.1017/s0950268800049694.

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SUMMARYA collection ofSalmonella enteritidisstrains isolated in Switzerland (1965–90) was characterized. The phage type and plasmid profile of isolates were compared with the copy number and insertion loci of the DNA insertion element IS200. Three clonal lines ofS. enteritidiswere identified by IS200profile; the various phage types were subtypes reproducibly associated with one of these lines. All human and poultry isolates contained a 38 Mda plasmid which hybridized with a mouse virulence-associated gene probe. InS. enteritidis, the IS200profile is a race-specific molecular marker of the chro
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Dissertationen zum Thema "Phage MDA"

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Mouville, Clémence. "Interaction entre les pili de type IV et le phage filamenteux MDA : impact potentiel sur la virulence de Neisseria meningitidis." Electronic Thesis or Diss., Université Paris Cité, 2024. http://www.theses.fr/2024UNIP5235.

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Neisseria meningitidis (Nm) est une bactérie commensale du nasopharynx humain qui traverse quelques fois la barrière nasopharyngée et se propage dans la circulation sanguine jusqu'à atteindre les méninges. Un bactériophage filamenteux appelé MDA (Meningococcal Disease Associated) est associé aux infections invasives à méningocoques chez les jeunes adultes. Le MDA semble augmenter l'incidence de la maladie en augmentant la colonisation bactérienne au point d'entrée. L'objectif de ce travail a été de comprendre le mécanisme moléculaire précis de l'infection de Nm par le MDA. L'étude des mutants
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Kolb, Johann. "Calibration and test tools for MCAO system : application to the ESO demonstrator MAD." Paris 6, 2005. http://www.theses.fr/2005PA066599.

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Gimeno, Pascal. "Caractérisation d'échantillons de 3,4-méthylènedioxyméthamphétamine (MDMA) par analyse en chromatographie gazeuse - spectrométrie de masse des impuretés de synthèse." Lyon 1, 2003. http://www.theses.fr/2003LYO1T002.

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La 4e de couverture indique : "Ce travail présente une méthode d'analyse qualitative et semi-quantitative des impuretés de synthèse de la 3,4-méthylènedioxyméthamphétamine (MDMA) par chromatographie gazeuse couplée à la spectrométrie de masse (GC/MS). L'identification des impuretés trouvées dans des échantillons de saisie a été réalisée par ionisation en impact électronique (Ei) suivie d'une détection en mode full scan. La majorité des impuretés d'intérêt a ensuite été confirmée par une analyse en ionisation chimique positive (CI+) suivi d'une fragmentation MS-MS de l'ion moléculaire obtenu. D
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Wilburn, Kaylee Marie. "Isolation and Characterization of Broad Host Range Phage that infect P. aeruginosa Pathogens." Bowling Green State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1594224687661359.

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Sidi-Boumedine, Réda. "Etude des systèmes gaz acide - Alcanolamine - Eau : Mesures couplées de composition de la phase liquide et de solubilité." Paris, ENMP, 2003. http://www.theses.fr/2003ENMP1144.

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L'absorption des gaz acides (CO2, H2S) par des solutions aqueuses d'alcanolamines est un procédé couramment employé au sein de l'industrie du traitement des gaz. Le dimensionnement et l'optimisation de ce type de procédé nécessitent l'utilisation d'un outil thermodynamique permettant une représentation réaliste des équilibres liquide-vapeur de ces systèmes d'électrolytes. Néanmoins, les données de solubilité sur lesquelles sont ajustés les paramètres des modèles sont le plus souvent incohérentes. De plus, malgré leur importance pour la modélisation, il n'existe de données expérimentales de com
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Wang, Jiong. "Analytical studies on the force-induced phase transitions in slender shape memory alloy cylinders layers /." access full-text access abstract and table of contents, 2009. http://libweb.cityu.edu.hk/cgi-bin/ezdb/thesis.pl?phd-ma-b23750546f.pdf.

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Thesis (Ph.D.)--City University of Hong Kong, 2009.<br>"Submitted to Department of Mathematics in partial fulfillment of the requirements for the degree of Doctor of Philosophy." Includes bibliographical references (leaves [214]-224)
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Jacq, Sylvie. "Décodage itératif des codes produits : "turbo-codes en blocs", et évaluations de leurs performances pour des modulations MDP et MAQ sur canal de Gauss et de Rayleigh." Limoges, 1996. http://www.theses.fr/1996LIMO0056.

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Rosa, Wesley de Oliveira. "Síntese e caracterização de géis para cromatografia de exclusão por tamanho via reticulação de Acetato de Celulose com 4,4' - Difenilmetano Diisocianato (MDI)." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/8327.

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Submitted by Milena Rubi (milenarubi@ufscar.br) on 2016-11-09T14:11:31Z No. of bitstreams: 1 ROSA_Wesley_2016.pdf: 8516860 bytes, checksum: ee5a7fd54adf8975660601cc883291f2 (MD5)<br>Approved for entry into archive by Milena Rubi (milenarubi@ufscar.br) on 2016-11-09T14:11:44Z (GMT) No. of bitstreams: 1 ROSA_Wesley_2016.pdf: 8516860 bytes, checksum: ee5a7fd54adf8975660601cc883291f2 (MD5)<br>Approved for entry into archive by Milena Rubi (milenarubi@ufscar.br) on 2016-11-09T14:11:50Z (GMT) No. of bitstreams: 1 ROSA_Wesley_2016.pdf: 8516860 bytes, checksum: ee5a7fd54adf8975660601cc883291f2 (MD
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Koot, Dwayne Jonathan. "Strategic pre-clinical development of Riminophenazines as resistance circumventing anticancer agents." Thesis, University of Pretoria, 2012. http://hdl.handle.net/2263/24163.

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Cancer is responsible for upward of 13% of human deaths. Contemporary chemotherapy of disseminated cancer is often thwarted by dose limiting systemic toxicity and by multi-drug resistance (MDR). Riminophenazines are a novel class of potential anticancer agents that possess a potent multi-mechanistic antineoplastic action. Apart from their broad action against intrinsic, non-classical resistance, Riminophenazines inhibit the action of Pgp and hypothetically all ABC transporters demonstrating their great utility against classical MDR. Considering that combination chemotherapy is the norm, the vi
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Ulbricht, David, Jan Pippel, Stephan Schultz, René Meier, Norbert Sträter та John T. Heiker. "A unique serpin P1′ glutamate and a conserved β-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin)". Portland Press, 2015. https://ul.qucosa.de/id/qucosa%3A33439.

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SerpinA12 (vaspin) is thought to be mainly expressed in adipose tissue and has multiple beneficial effects on metabolic, inflammatory and atherogenic processes related to obesity. KLK7 (kallikrein 7) is the only known protease target of vaspin to date and is inhibited with a moderate inhibition rate. In the crystal structure, the cleavage site (P1-P1′) of the vaspin reactive centre loop is fairly rigid compared with the flexible residues before P2, possibly supported by an ionic interaction of P1′ glutamate (Glu379) with an arginine residue (Arg302) of the β-sheet C. A P1′ glutamate seems high
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Bücher zum Thema "Phage MDA"

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Bilanin, Jeanne E. A staffing levels study for the Maryland Aviation Administration (MAA), phase II. Institute for Governmental Service, University of Maryland System, 1991.

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Gardner, Brian M. A staffing levels study for the Maryland Aviation Administration (MAA), phase III. Institute for Governmental Service, University of Maryland System, 1991.

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Authority, Massachusetts Water Resources, ed. MDC-MWRA long range water supply study and environmental impact report-2020: Phase II report. Massachusetts Water Resources Authority, 1990.

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DeLeonardis, Lisa. A phase II archaeological investigation of the cultural resources associated with the Carroll-Caton House courtyard, 18BC6, Baltimore, Maryland: Report. The Center, 1995.

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Padma-ye-śes, Dbal-śul. Gnas chen Phag-mo-ri'i ngo sprod mdor bsdus: Dag snang 'o mtsho 'phel ba'i zla zer. Zhang-kang gyi ling dpe skrun khang, 2007.

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Bonito, Arthur J., Nancy D. Berkman, and May Kuo. Analysis of Medicare beneficiary knowledge data using the Medicare Current Beneficiary Survey (MCBS): Phase 3.2 : final report. RTI International, Health, Social, and Economics Research, 2003.

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Berkman, Nancy D. Analysis of Medicare beneficiary knowledge data using the Medicare Current Beneficiary Survey (MCBS): Phase 3.1 : final report. RTI, 2002.

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Anderson, Wayne L. Analysis of the 1998 Medicare Current Beneficiary Survey for use in monitoring the National Medicare Education Program: Phase two report. Research Triangle Institute, 2000.

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Padma-tshe-dbaṅ-rgyal-po, Bstan-gñis-gliṅ-pa. Rdo rje phag moʼi zab khrid kyi skor: A collection of revelations focussing upon the practice of Vajravārāhī in mystical union with Hayagrīva. National Library of Bhutan, 1985.

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United States. Congress. Senate. Committee on Labor and Human Resources. Chlorofluorocarbon propellants in the atmosphere, inhalers, and regulation: Hearing before the Committee on Labor and Human Resources, United States Senate, One Hundred Fifth Congress, second session, on examining the federal role in the implementation of Title VI of the Clean Air Act as it relates to the use of chlorofluorocarbons (CFC) in metered-dose inhalers (MDI), and an advance notice of proposed rulemaking to phase out essential-use exemptions for CFC-based MDI's, April 2, 1998. U.S. G.P.O., 1998.

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Buchteile zum Thema "Phage MDA"

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Onida, Francesco, and Yves Chalandon. "Myelodysplastic/Myeloproliferative Neoplasms." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_76.

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AbstractThe myelodysplastic syndrome-myeloproliferative neoplasms (MDS/MPNs) are a heterogeneous group of hematologic malignancies characterized by dysplastic and myeloproliferative clinical, laboratory, and morphological overlapping features, both in marrow and in blood. MDS/MPNs include chronic myelomonocytic leukemia (CMML), MDS/MPN with neutrophilia, MDS/MPN with SF3B1 mutation (in its absence with ringed sideroblasts) and thrombocytosis (MDS/MPN-SF3B1-T), and MDS/MPN not otherwise specified (MDS/MPN-NOS). Prognosis of MDS/MPN is highly variable, being dismal in the majority of patients with CMML, MDS/MPN with neutrophilia and MDS/MPN-NOS. In the absence of disease-modifying treatment options, allo-HCT represents the only curative option for eligible patients. With regard to allo-HCT indication in CMML patient, a number of prognostic systems have been developed over the years. As far as pre-transplant phase, in high-risk patients with MDS/MPN and low blast count (&lt;10%), upfront transplantation is the most frequently preferred strategy. In patients with high blast count, pre-transplant treatment with HMAs, or combination of HMAs with other new agents in clinical trials may be considered. In case of rising leukocytosis and/or organ infiltration, hydroxyurea is the drug of choice. In MDS/MPN patients, the choice of conditioning regimen depends on many different conditions, the major ones being comorbidities, patient age, disease phase at transplant, type of donor, and HSC source. In general, myeloablative regimens may be advisable in young patients without comorbidities aiming to reduce the relapse risk, while reduced-intensity regimens are preferred for patients with older age or comorbidities. As disease recurrence represents the major cause of transplant failure in MDS/MPN, there is a growing interest toward possible post-transplant treatment strategies, both as preemptive and as prophylactic modalities.
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Pinto, Mónica, Lidia Fuentes, Luis Fernández, and Juan A. Valenzuela. "Using AOSD and MDD to Enhance the Architectural Design Phase." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-05290-3_48.

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Rosenberger, W. F., L. M. Haines, and I. Perevozskaya. "Constrained Bayesian Optimal Designs for Phase I Clinical Trials: Continuous Dose Space." In mODa 6 — Advances in Model-Oriented Design and Analysis. Physica-Verlag HD, 2001. http://dx.doi.org/10.1007/978-3-642-57576-1_25.

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Zhou, Zongwei, Yibo Xue, Junda Liu, Wei Zhang, and Jun Li. "MDH: A High Speed Multi-phase Dynamic Hash String Matching Algorithm for Large-Scale Pattern Set." In Information and Communications Security. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-77048-0_16.

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Hoffmann, Stefan R. K., Christine A. Deillon, and Bernd Gutte. "Solid Phase Synthesis of Seleno-Methionine Peptides by tBoc/Bzl and Fmoc/tBu Protection Strategy Suitable for the Crystallographic Phase Determination by Multi-Wavelength Anomalous Diffraction (MAD)." In Peptides: The Wave of the Future. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0464-0_74.

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Passie, Torsten. "Rise of a Recreational Drug." In The History of MDMA, edited by Andrew Dennis. Oxford University PressOxford, 2023. http://dx.doi.org/10.1093/oso/9780198867364.003.0004.

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Abstract This chapter provides an overview of the early, rather unknown, phase of MDMA as a recreational drug. MDMA was first detected by scientists in a forensic laboratory in 1970, and then a few more times up until 1976. A previously unknown document of the United States DEA has been used to describe these early detections. The evidence shows that up until 1976, the distribution of MDMA was rather limited and MDMA was initially produced as a ‘legal alternative for MDA’, which had been scheduled in 1970. Mention is made of a 1970 science fiction novel by the prominent writer Stanislav Lem, which seemed to describe the effects of MDMA, as well as of new documentation suggesting that the American drug chemist Alexander Shulgin had synthesized MDMA in 1975. A description of the American drug guru Timothy Leary’s first experiences with MDMA in 1978 is also given. There were two ‘hotspots’ for MDMA use during the 1970s: initially in the Midwest, and from 1976 onwards in Oregon and California.
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Elayoni Emmanuel, Igomu. "Challenges of Phage Therapy as a Strategic Tool for the Control of Salmonella Kentucky and Repertoire of Antibiotic Resistance Genes in Africa." In Bacteriophages in Therapeutics. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95329.

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Salmonella Kentucky ST198 (S. Kentucky ST198) is the most ubiquitous multidrug resistant (MDR) strain posing the greatest threat to public health, livestock and food industry in Africa. The reinvention of bacteriophage (Phage) as a non-antibiotic alternative only gives a glimmer of hope in the control of MDR strains of Salmonellae. S. Kentucky ST198 posses’ chromosomal and plasmid factors capable of been co-opted into phage mediated transduction and co-transduction of antibiotic resistance genes (ARGs) as well as cross-serovar transduction of ARGs. Phage DT104, DT120 and P-22 like prophages like PDT17 and ES18 together have been shown to be capable of transducing and co-transducing the classical ACSSuT resistance phenotype identified in most S. Kentucky ST198 strain on the continent. Also, the institution of fluoroquinolones and third generation cephalosporin for salmonellosis treatment in animals or human infected by S. Kentucky ST198 strain resistant to these drugs can induce Salmonella phage transduction of kanamycin between different Salmonella serovars if present. This review highlights possible risk associated with the use of known Salmonella phages in the control of S. Kentucky ST198 and the need for chromosomal and plasmid tracking of genes prior to the institution of phage therapy on the continent.
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Yan, Wei, Subhankar Mukhopadhyay, Kenneth Kin Wah To, and Sharon Shui Yee Leung. "Potential of Inhaled Bacteriophage Therapy for Bacterial Lung Infection." In Bacteriophages [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96660.

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Phage therapy as a promising alternative antimicrobial to treat multidrug resistant (MDR) bacteria related lung infections, has drawn significant attention in clinical trials and bench-scale study in the recent decade, and the therapeutic effect of local delivery of phage has been demonstrated by several clinical reports. This book chapter discusses the current clinical development of inhaled phage therapy followed by the advancement of phage formulation designs for respiratory delivery of phage using various inhalation devices and their in vivo efficacy. The development of combination therapy of phage and antibiotics to combat MDR bacteria associated lung infections is also covered to reflect the current clinical practice. Lastly, we also share our insights on the challenges of advancing inhaled phage therapy and potential directions for future research.
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Kalra, Aakanksha, Sakshi Piplani, and Ravi Ranjan Kumar Niraj. "Current Therapeutic Options and Challenges for MDR." In Current Developments in the Detection and Control of Multi Drug Resistance. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815049879122010009.

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Multiple-Drug Resistance (MDR) against many antibiotics and other therapeutic agents is a major concern for health care providers and researchers in the field. Due to tremendous rise in MDR cases, researchers are in search of potent therapeutic options or alternatives to overcome MDR. Here, in this chapter, we will discuss the current status of the common as well as advanced methods which have been developed so far for the treatment of MDR and also the challenges and opportunities in each of those methods. This chapter discusses common methods used for the treatment of MDR, i.e., major antibiotics used for the treatment of MDR bacteria and synergistic approaches by the combination of different antibiotics. Along with common treatments used against MDR bacteria, this chapter also discusses current treatments like anti microbial peptides, anti-virulence compounds, phage therapy and drug repurposing approaches for MDR treatment.
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Doublie, S., and C. W. Carter. "Preparation of Selenomethionyl Protein Crystals." In Crystallization of Nucleic Acids and Proteins. Oxford University PressOxford, 1992. http://dx.doi.org/10.1093/oso/9780199632459.003.0014.

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Abstract For many years multiple isomorphous replaccement (MIR) has been the method of choice for phase determination. In most cases MIR is reliable, but occasionally it fails: heavy-atom binding may not occur, or if it does it may lead to loss of isomorphism. Use of Multiwavelength Anomalous Dispersion (MAD) has been introduced to circumvent these two problems (I, 2). On the one hand, the MAD method exploits the presence of anomalous scatterers, such as Cu or Fe in metalloproteins, or any of the heavy-metal derivatizing agents. On the other hand, all measurement relevant to determining a single phase can be made on the same crystal o isomorphism is exact, and electron density maps are of very high quality (3, 4). Thus, the MAD method will likely become a preferred method for phase determination.
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Konferenzberichte zum Thema "Phage MDA"

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Zdańkowski, Piotr, Maksymilian Chlipała, Mikołaj Rogalski, and Maciej Trusiak. "Bedrosian theorem problem in quantitative phase imaging." In Digital Holography and Three-Dimensional Imaging. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/dh.2024.m3a.2.

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In this study we highlight the significance of the Bedrosian theorem, stating that strong sample-induced amplitude variations can impact the result of the phase demodulation, challenging the often-overlooked assumptions in phase reconstruction.
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Berguiga, Lotfi, Théo Girerd, Fabien Mandorlo, Cécile Jamois, Taha Benyattou, and Lydie Ferrier. "Young’s interference hologram generated with a spatial light modulator for nanophotonic sensor." In Digital Holography and Three-Dimensional Imaging. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/dh.2024.m4a.5.

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A new method of phase interrogation of photonic sensors is proposed. The method relies on the Young’s interference experiment generated by holography with a DMD. Phase variations have been measured for photonic crystal temperature sensor.
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Silva, Alejandro, Miguel Arocena, Ariel Fernández, and Julia R. Alonso. "Quantitative Phase Microscopy of hypoxic epithelial cells using the Transport of Intensity Equation." In Digital Holography and Three-Dimensional Imaging. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/dh.2024.m3a.3.

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Quantitative Phase Imaging of epithelial cells under different levels of hypoxia can be achieved by acquiring a multifocus stack with a 3D printed microscope and using the Transport of Intensity Equation. Experimental results are provided.
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Pandey, Dhruvam, Viren S. Ram, and Rajshekhar Gannavarpu. "Neural network based subspace analysis for estimation of phase derivatives from noisy interferograms." In Digital Holography and Three-Dimensional Imaging. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/dh.2024.m2a.2.

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This article introduces a robust phase derivative estimation method using deep learning-assisted subspace analysis. Simulation results validate the performance of the proposed approach under severe noise conditions.
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Guadagnini, Jacopo, and Gabriele De Zaiacomo. "Multidisciplinary Design Optimisation for Missionisation of Re-entry Vehicles: Preliminary Mission Design and Mission Capabilities Evaluation of Winged Re-Entry Vehicles Case Study." In ESA 12th International Conference on Guidance Navigation and Control and 9th International Conference on Astrodynamics Tools and Techniques. ESA, 2023. http://dx.doi.org/10.5270/esa-gnc-icatt-2023-126.

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The work presented in this paper is part of the European H2020 ASCenSIon program. In this context, the overall purpose of this research is the definition and development of a Mission Analysis and GNC missionisation tool for autonomous re-entry vehicles. In recent years, space agencies and private firms are investing in reusable spacecraft and launch vehicles to make space access and in-orbit studies more economically and environmentally sustainable. The re-flight capability, requested by a reusable space system, motivates the need for a dedicated missionisation tool. The objective of missionis
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Boda, Z., G. Pfliegler, I. Tornai, M. Udvardy, J. Hársfalvi, and K. Rak. "LONG-TERM COUMAROL PLUS SMALL DOSE ASA THERAPY IN PATIENTS WITH PROSTHETIC HEART VALVE. SOME QUESTIONS OF LABORATORY CONTROL." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643268.

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Thromboembolism in patients with prosthetic heart valves remains a major time-related problem (Sullivan 1971, Dale 1976, Chesebro 1983). Patients receiving anticoagulant plus antiplatelet agent have the lowest incidence of thromboembolism but the risk of bleeding is not negligible. The laboratory control of combined therapy is unsolved.This study considers the thromboembolic prophylaxis of 38 patients with prosthetic heart valve. Cou-marol treatment was combined with ASA (1 000 mg/week, 36 months follow up).Prothrombin ratio was used in control of the oral anticoagulant therapy. Malondialdehyd
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De Maria, S., A. Liati, and M. Monti. "Oxygen Removal in Water Injection: A Life-Cycle Cost Comparison Between Vacuum Degassing and Membrane Deaeration Technologies." In SPE Water Lifecycle Management Conference and Exhibition. SPE, 2024. http://dx.doi.org/10.2118/218995-ms.

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Abstract This paper aims at making an overall comparison based on life-cycle costs (LCC) between vacuum degassing and membrane deaeration, the two main technologies for removing oxygen from injection water in the energy upstream sector. Traditional degassing technology based on vacuum towers (VT), where oxygen is stripped from liquid water falling on random packing under vacuum conditions, has been compared with membrane deaeration (MDA), a potentially emerging technology in which oxygen moves from the liquid phase through a gas-permeable membrane toward an oxygen-depleted gas stream. The comp
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Abdellatif, Lasbahani, Mostafa Chhiba, and Oussama Mjihil. "Deals with integrating of security specifications during software design phase using MDA approach." In ICC '17: Second International Conference on Internet of Things, Data and Cloud Computing. ACM, 2017. http://dx.doi.org/10.1145/3018896.3065835.

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Yang, Hedong, and Clark C. Guest. "Binary phase-only filters with improved discrimination: maximized amplitude difference method." In OSA Annual Meeting. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/oam.1992.thq2.

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A new design method, the maximized amplitude difference (MAD) method, is developed to improve the discrimination of binary phase-only filters (BPOFs). In this approach, we construct an energy function that represents the weighted difference between the amplitude of the autocorrelation peak caused by the target signal and that of the cross-correlation peak caused by the nontarget signal. The weight determines the suppression level of the crosscorrelation peak. The best phases for each of the two peaks are determined through a fast deterministic search algorithm. A BPOF that minimizes the energy
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Tarbell, T. D., D. S. Acton, and Z. A. Frank. "Phase Diversity Wavefront Sensing and Image Reconstruction on the MDI instrument at L1." In Adaptive Optics. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/adop.1996.awd.4.

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The Michelson Doppler Imager (MDI) is a spectral imaging experiment on the ESA-NASA Solar and Heliospheric Observatory spacecraft (SOHO-see Domingo et al., 1995). SOHO was launched in December, 1995, and reached its final orbit about the Earth-Sun Lagrangian point L1 in mid-February, 1996. This point, about 1.5×l06 km towards the Sun, is where the Earth’s and Sun’s gravity balance, allowing a nearly stable orbit ideal for continuous observations of the Sun and solar wind. MDI is collecting the observational data for the Solar Oscillations Investigation (SOI), a study of the interior structure
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Berichte der Organisationen zum Thema "Phage MDA"

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Vaucher, Gail, Jeffrey Swanson, John Raby, et al. Meteorological Sensor Array (MSA) - Phase I Volume 1 (Proof of Concept" Overview)". Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada608929.

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Vaucher, Gail, and Robert Edmonds. Meteorological Sensor Array (MSA)-Phase I. Volume 3 (Pre-Field Campaign Sensor Calibration). Defense Technical Information Center, 2015. http://dx.doi.org/10.21236/ada622325.

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Dinovitzer, Aaron. PR-214-153739-WEB ERW Fatigue Life Integrity Management Improvement - Phase III. Pipeline Research Council International, Inc. (PRCI), 2019. http://dx.doi.org/10.55274/r0011614.

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Tuesday, September 17, 2019 11:00 a.m ET PRESENTER: Aaron Dinovitzer, MA Sc., MBA, PEng, BMT Canada HOST: Mark Piazza, Colonial Pipeline Company MODERATOR: John Lynk, PRCI CLICK THE BUY/DOWNLOAD BUTTON TO ACCESS THE WEBINAR REGISTRATION LINK Join the PRCI Integrity and Inspection Technical Committee as they present research results that set out to evaluate the level of conservatism inherent to current state-of-practice procedures using full-scale fatigue testing. Learning outcomes/benefits of attending: - Understand the sources of conservatism, and how to improve the accuracy of, fatigue life
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Miller. L51699 Diverless Pipeline Repair Clamp Phase III. Pipeline Research Council International, Inc. (PRCI), 1993. http://dx.doi.org/10.55274/r0010218.

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Offshore oil and gas developments are underway for water depths beyond which divers can function. The economic lifelines of these projects are the pipelines which will transport the products to shore. In preparation for the day when one of these pipelines will require repair because of a leak, the Pipeline Research Committee of Pipeline Research Council International, Inc. is funding research directed at developing diverless pipeline repair capabilities. This Report summarizes the results of the third and final phase of this project. Phase III work included design, manufacture, and dry testing
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McNealy. L52295 Fundamentals and Performance Improvements of ILI Technologies for Mechanical Damage Inspection. Pipeline Research Council International, Inc. (PRCI), 2008. http://dx.doi.org/10.55274/r0010677.

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The objective of this effort is to assist the pipeline industry in selecting ILI technologies that are best suited for detecting and sizing the types of mechanical damage that may pose integrity concerns, and/or are required to be addressed by the existing Regulatory Rules. The practical need is driven by both the recent changes in Regulatory requirements, vis-à-vis mechanical damage, and the latest developments of ILI technologies aiming to detect and size such damage. Based on the information provided by the six participating ILI vendors, and taking fulladvantage of extensive previous work,
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Jinawath, Supatra. Fabrication of porous calcium phosphates. Chulalongkorn University, 2002. https://doi.org/10.58837/chula.res.2002.29.

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The starting materials for this experiment were monocalcium phosphate monohydrate, dicalcium phosphate dihydrate and anhydrous dicalcium phosphate synthesized in-house from the by-product of a local bone-gelatin manufacture. Porous calcium phosphates comprising hydroxyapatite either as a single phase or a composite containing traces of its congeners. i.e., β-TCP were fabricated in the forms of granules and compacts. The characteristics of typical compacts produced were 37 v % apparent porosity with interconnected pores of diameter 1-30 µm, and flexural and compressive strengths of 17.51 and 78
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Gurung, Bijan, J. Hutchinson, Brian Peterson, et al. Exploring spatial patterns of overflights at Olympic National Park. National Park Service, 2024. http://dx.doi.org/10.36967/2304991.

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This study explored spatial patterns of overflights at Olympic National Park (OLYM). Overflights were analyzed from July 27th, 2021 to January 2nd, 2023 using Automatic Dependent Surveillance-Broadcast (ADS-B) data with a total of 525 days of data. Data were collected using data loggers that were deployed at Blyn (located outside of OLYM), Hurricane Ridge, and Hoh Rain Forest. The first phase of analysis focused on all overflights and found a high concentration of overflights above the northeastern portion of OLYM, and definitive flight corridors were identified across the park. The second pha
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Author, Unknown. PR-328-6352-R01 LaserScan Mapping and Reporting of Plain Dents in Support of PRCI - Phase 2. Pipeline Research Council International, Inc. (PRCI), 2007. http://dx.doi.org/10.55274/r0012169.

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As part of the PRCI sponsored project (MD 1-2), ten defects were introduced on a three-meter section of a 30-inch pipe. Detailed mapping of all the defects was performed using a 3D LaserScan system by Applus RTD. The objective of the scan was to get a detailed, high resolution, high density, three-dimensional representation of the defects and to provide some critical metrics about the defects.
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Tangpasuthadol, Varawut, and Amarawan Intasiri. Silica reinforement of natural rubber by sol-gel process in latex. Chulalongkorn University, 2005. https://doi.org/10.58837/chula.res.2005.32.

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Beside carbon black, silica powder is the other important filler used to reinforce various colored rubber products. In order to improve the compatibility between silica particles and rubber phase, this work has focused on preparing an NR composite, reinforced by silica generated inside the NR matrix or ‘in situ’. The silica particle was formed by a sol-gel process of tetraethoxysilane (TEOS) dispersed in NR latex. The latex used was concentrated latex having 60% rubber content, and already contained water and ammonia, two ingredients needed for the sol-gel reaction. The conversion of TEOS to s
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Botros, Geerligs, and Given. L52187 Decompression Response of High-Pressure Natural Gas Pipelines Under Rupture or Blowdown Conditions. Pipeline Research Council International, Inc. (PRCI), 2004. http://dx.doi.org/10.55274/r0010394.

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The Pipeline Research Council International, Inc. found that Scandpower has software that is capable of predicting the transient response of a pipeline segment transporting either conventional or enriched dense phase natural gas mixtures when subjected to a controlled blow down or an uncontrolled rupture event. Consequently PRCI expressed a desire to pursue an experimental work to provide the basis for evaluating the adequacy of the existing software and/or define further development if any. NOVA Research and Technology Corporation (NRTC) was awarded a contract to perform the experimental work
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