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Auswahl der wissenschaftlichen Literatur zum Thema „Periodontitis Prevention“
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Zeitschriftenartikel zum Thema "Periodontitis Prevention"
1
Wadia, Reena. „The Prevention of Periodontitis“. Dental Update 47, Nr. 10 (02.11.2020): 871–76. http://dx.doi.org/10.12968/denu.2020.47.10.871.
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Prevention of periodontitis may be primary or secondary. This article summarizes the key steps involved, with a focus on oral hygiene practices, risk factor control, professional mechanical plaque removal and supportive periodontal therapy. CPD/Clinical Relevance: All dental professionals play a key role in the prevention of periodontitis.
2
Rakic, Mia, Natasa Pejcic, Neda Perunovic und Danilo Vojvodic. „A Roadmap towards Precision Periodontics“. Medicina 57, Nr. 3 (03.03.2021): 233. http://dx.doi.org/10.3390/medicina57030233.
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Periodontitis is among the most common health conditions and represents a major public health issue related to increasing prevalence and seriously negative socioeconomic impacts. Periodontitis-associated low-grade systemic inflammation and its pathological interplay with systemic conditions additionally raises awareness on the necessity for highly performant strategies for the prevention and management of periodontitis. Periodontal diagnosis is the backbone of a successful periodontal strategy, since prevention and treatment plans depend on the accuracy and precision of the respective diagnostics. Periodontal diagnostics is still founded on clinical and radiological parameters that provide limited therapeutic guidance due to the multifactorial complexity of periodontal pathology, which is why biomarkers have been introduced for the first time in the new classification of periodontal and peri-implant conditions as a first step towards precision periodontics. Since the driving forces of precision medicine are represented by biomarkers and machine learning algorithms, with the lack of periodontal markers validated for diagnostic use, the implementation of a precision medicine approach in periodontology remains in the very initial stage. This narrative review elaborates the unmet diagnostic needs in periodontal diagnostics, the concept of precision periodontics, periodontal biomarkers, and a roadmap toward the implementation of a precision medicine approach in periodontal practice.
3
Chapple, Iain L. C., Fridus Van der Weijden, Christof Doerfer, David Herrera, Lior Shapira, David Polak, Phoebus Madianos et al. „Primary prevention of periodontitis: managing gingivitis“. Journal of Clinical Periodontology 42 (31.03.2015): S71—S76. http://dx.doi.org/10.1111/jcpe.12366.
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4
Nawrot-Hadzik, Izabela, Adam Matkowski, Jakub Hadzik, Barbara Dobrowolska-Czopor, Cyprian Olchowy, Marzena Dominiak und Paweł Kubasiewicz-Ross. „Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects“. Nutrients 13, Nr. 1 (07.01.2021): 165. http://dx.doi.org/10.3390/nu13010165.
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Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. They exhibit antioxidant, anti-inflammatory, cytoprotective, as well as antimicrobial activity. The latter property is important in the prevention and treatment of periodontal diseases. Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting the periodontium. Using non-toxic and efficient natural products such as flavanol derivatives can significantly contribute to alleviating periodontitis symptoms and preventing the disease’s progress. Therefore, a comprehensive systematic review of proanthocyanidins and flavan-3-ols in the prevention and treatment of periodontitis was performed. The present paper reviews the direct antibacterial effects of these compounds against periodontic pathogens. The immunomodulatory effects, including animal and clinical studies, are included in a separate, parallel article. There is significant evidence supporting the importance of the antibacterial action exerted by proanthocyanidins from edible fruits, tea, and medicinal herbs in the inhibition of periodontitis-causing pathogens.
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Nawrot-Hadzik, Izabela, Adam Matkowski, Jakub Hadzik, Barbara Dobrowolska-Czopor, Cyprian Olchowy, Marzena Dominiak und Paweł Kubasiewicz-Ross. „Proanthocyanidins and Flavan-3-Ols in the Prevention and Treatment of Periodontitis—Antibacterial Effects“. Nutrients 13, Nr. 1 (07.01.2021): 165. http://dx.doi.org/10.3390/nu13010165.
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Flavan-3-ols and their oligomeric forms called proanthocyanidins are polyphenolic compounds occurring in several foodstuffs and in many medicinal herbs. Their consumption is associated with numerous health benefits. They exhibit antioxidant, anti-inflammatory, cytoprotective, as well as antimicrobial activity. The latter property is important in the prevention and treatment of periodontal diseases. Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process affecting the periodontium. Using non-toxic and efficient natural products such as flavanol derivatives can significantly contribute to alleviating periodontitis symptoms and preventing the disease’s progress. Therefore, a comprehensive systematic review of proanthocyanidins and flavan-3-ols in the prevention and treatment of periodontitis was performed. The present paper reviews the direct antibacterial effects of these compounds against periodontic pathogens. The immunomodulatory effects, including animal and clinical studies, are included in a separate, parallel article. There is significant evidence supporting the importance of the antibacterial action exerted by proanthocyanidins from edible fruits, tea, and medicinal herbs in the inhibition of periodontitis-causing pathogens.
6
Fares, Hussein Nasser, Halim Nagem Filho, Nasser Hussein Fares, Giordana Gregório Fritsch und Rafael Julivan Gomes da Silva. „Doença periodontal e risco de complicações da Covid-19“. Full Dentistry in Science 12, Nr. 47 (2021): 126–31. http://dx.doi.org/10.24077/2021;1247126131.
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The Covid-19 complexity is caused by severe inflammation and some signs are common with periodontitis. The attributes of periodontitis are pathophysiological in response to cytokines, which are chemotactic and recruit inflammatory cells. This article aims to investigate a probable link between periodontal disease that increases severity of Covid-19 and to consider the risk factors that influence the outcome of Covid-19 infections and the importance of periodontal health in prevention. Dental surgeons are high-risk professionals, especially periodontists, due to the frequent use of ultrasound and other aerosol-generating surgical instruments. In fact, in addition to the nasal passages, the mouth is a privileged place of contamination. Urgent or emergent dental care is often invasive and requires aerosolization. It is plausible that periodontitis aggravates an inflammatory process resulting from the infection, problems often linked to the most serious cases of Covid-19.
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Lee, Yen-Tzu, I.-chieh Mao und Shih-Te Tu. „Periodontitis prevention program effectively reduced the incidence of periodontitis in diabetic patients“. Diabetes Research and Clinical Practice 120 (Oktober 2016): S147. http://dx.doi.org/10.1016/s0168-8227(16)31303-1.
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8
Bergstrom, Jan. „Periodontitis Low-Susceptible Subjects Receiving Regular Primary Prevention do Not Develop Periodontitis“. Journal of Evidence Based Dental Practice 8, Nr. 1 (März 2008): 33–34. http://dx.doi.org/10.1016/j.jebdp.2007.12.002.
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Sharma, Nikhil, und Nitin Khuller. „Periodontal Vaccine: A New Paradigm for Prevention of Periodontal Diseases“. Journal of Oral Health and Community Dentistry 4, Spl (2010): 23–28. http://dx.doi.org/10.5005/johcd-4-spl-23.
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ABSTRACT Vaccination is a process that induces specific immune resistance to a bacterial or viral infectious disease. Vaccines have prevented several infectious diseases for many years, and are still being investigated. In late eighteenth century, Edward Jenner developed and established the principle of vaccination using the cross protection conferred by cowpox virus, which is non pathogenic in humans. Regarding a vaccine against the periodontal disease, the complexity of the periodontopathic bacteria might be a problem in determination of Antigens. Among some 300 species of bacteria involved in subgingival plaque, 5-7 species have been implicated in the etiology of periodontitis but one or two species; P.gingivalis or B. forsythus might play an important role as primary pathogens. Vaccination accomplished can be active immunization, passive immunization or DNA vaccination, made from the antigenic epitopes in periodontopathic bacteria. In light of the increasing evidence that periodontitis significantly increases risk for potentially fatal diseases such as coronary heart disease, stroke and complications from diabetes mellitus a successful vaccine for periodontitis could have health benefits far exceeding the prevention of periodontitis.
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Zanza, Alessio, Rodolfo Reda, Francesco Pagnoni und Shankargouda Patil. „Future Trends in Endodontics: How Could Materials Increase the Long-Term Outcome of Root Canal Therapies?“ Materials 15, Nr. 10 (12.05.2022): 3473. http://dx.doi.org/10.3390/ma15103473.
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The goals of endodontic therapies are the prevention or the elimination of apical periodontitis of endodontic origin, ensuring the stability of results over time in order to avoid the recurrence of the disease and preventing teeth from requiring extraction [...]
Dissertationen zum Thema "Periodontitis Prevention"
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Nakka, Sravya Sowdamini. „Development of novel tools for prevention and diagnosis of Porphyromonas gingivalis infection and periodontitis“. Doctoral thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-52056.
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Periodontitis is a chronic inflammatory disease caused by exaggerated host immune responses to dysregulated microbiota in dental biofilms leading to degradation of tissues and alveolar bone loss. Porphyromonas gingivalis is a major periodontal pathogen and expresses several potent virulence factors. Among these factors, arginine and lysine gingipains are of special importance, both for the bacterial survival/proliferation and the pathological outcome. The major aim of this thesis was to develop and test novel methods for diagnosis and prevention of P. gingivalis infection and periodontitis. In study I, anti-P. gingivalis antibodies were developed in vitro for immunodetection of bacteria in clinical samples using a surface plasmon resonance (SPR)-based biosensor. Specific binding of the antibodies to P. gingivalis was demonstrated in samples of patients with periodontitis and the results were validated using real-time PCR and DNA-DNA checkerboard analysis. In study II, we elucidated the properties and antimicrobial effects of different lactobacillus species and the two-peptide bacteriocin PLNC8 αβ on P. gingivalis. L. plantarum NC8 and 44048 effectively inhibited P. gingivalis growth and pure PLNC8 αβ induced bacterial lysis by damaging P. gingivalis membrane. In study III, we demonstrated that PLNC8 αβ dose-dependently induces proliferation and release of growth factors in gingival epithelial cells (GECs). Furthermore, PLNC8 αβ decreased P. gingivalis-induced cytotoxic effects in GECs but did not alter the effect of gingipains on cytokine expression. In study IV, we elucidated the effects of anti-P. gingivalis antibodies and PLNC8 αβ in regulating cellular responses during P. gingivalis infection. Both antibodies and PLNC8 αβ modulated P. gingivalis-induced expression of growth factors in GECs, however, their effects were diminished when used in combination. The results of this thesis demonstrate a possible role of anti-P. gingivalis antibodies and PLNC8 αβ in prevention and treatment of P. gingivalis infection and periodontitis with no cytotoxic effects on human cells.
2
Yap, Benjamin C. M. „Rational design, synthesis and biological evaluation of porphyrin-antibiotic adducts targeting porphyromonas gingivalis“. Thesis, The University of Sydney, 2009. https://hdl.handle.net/2123/28209.
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The aim of the project was to rationally design, synthesise and evaluate porphyrin-based
growth inhibitors for the anaerobic bacterium Porphyromonas gingivalis, a key etiological
agent implicated in destructive periodontitis. Periodontal diseases are caused by harmful
bacteria that are present on the tooth’s surface and adjacent epithelium in the form of a
biofilm. The biofilm is a complex microflora of bacteria and the Gram—negative anaerobes that
predominate in the epithelial biofilm are of particular interest with respect to periodontal
disease. A goal of this research was to resolve the missing link in Koch’s postulates
establishing P. gingivalis as a key causative bacterium implicated in destructive periodontitis,
which has still not been answered due to the lack of a drug that selectively eliminates it from
the complex microflora in the biofilm.
In the process of developing a therapeutic agent to inhibit the growth of P. gingivalis, the
acquisition pathway for haem 1 was investigated. This is because P. gingivalis has an absolute
requirement for exogeneous haem 1 as a growth factor. Optimal haem 1 uptake by P.
gingivalis utilises characteristic surface proteins, the gingipains, for haemolysis, haemoglobin
proteolysis and haem 1 capture. The highly conserved HA2 domain embedded in the
haemagglutinin domain of the gingipains, is reported to act as a haemophore to capture and
bind haem 1 which allows the utilisation of this feature for targeted inhibition.
Previous work has established that the HA2 receptor recognises the porphyrin macrocycle
with the particular requirement for a free propionic acid side-chain rather than recognition of
the coordinated metal ion through chelation, a process used by other organisms with the HasA
porphyrin receptor. Current treatment of periodontal disease involves the use of antibiotics as
an adjunct to physical debridement. Metronidazole 2 is a potent nitroimidazole antibiotic with
excellent activity against anaerobes. However, its broad spectrum of activity results in
unwanted side effects. Consequently, work was set out to design and synthesise a porphyrin—
antibiotic adduct that would act as a “Trojan horse” to improve the delivery of 2 into P.
gingivalis.
In this work, various porphyrin-antibiotic adducts were designed as potential highly selective
P. gingivalis inhibitors, a key point being that they are based on the use of free-base
porphyrins to render them unpalatable to other organisms. In the process, a porphyrin—
antibiotic adduct 25a and 25b in which metronidazole 2 was directly attached to DPIX 6 by
an ester linkage was found to show much higher selectivity for P. gingivalis than to other
bacteria. A porphyrin—antibiotic adduct 31/32 in which the amine derivative of metronidazole
33 was directly attached to 6 by an amide linkage was found to be two—fold more active than 2
in inhibiting growth of P. gingivalis and twenty-fold more potent than 37 indicating that
adduct 31/32 acts as a single entity at the cell’s surface. The methyl ester version of this
adduct 37/38, in contrast, is not recognised by HA2 and is ineffective in inhibiting P.
gingivalis, leading to the conclusion that capture by HA2 may be necessary for activity of the
adducts. The mixture of the two regioisomers of the amide linked mono—metronidazole
adducts 31 and 32 were resolved by HPLC and were shown to have similar activities to each
other and to the mixture itself, suggesting that separation of the isomers is not crucial.
Adduct 40a and 40b whereby 33 was attached to DPIX 6 through a lysine was found to be as
potent as 2. However, efforts to improve its water solubility and potency by modifying the
lysine side—chain proved unsuccessful. This suggests limitations with respect to the amount of
modifications that can be carried out on the porphyrin—antibiotic adducts. Through this, new
insights were provided into the initially proposed HA2 binding site and a refinement of the
binding site was established to aid the design of future drugs.
An active lysine—linked porphyrin-antibiotic adduct 70a and 70b linked to a peptide-biotin
compound through the lysine side-chain was synthesised and was shown to be specifically
cleaved by the lysine—specific gingipains. When biotin 60 is replaced with an antibody to give
the adduct 67a and 67b, the adduct 67a and 67b has the potential to localise at the surface of
the diseased epithelium and provides the opportunity to create a depot of adducts localised at
the disease site and offer a targeted delivery approach. Synthetic efforts using Se-S chemistry
to link pophyrin—antibiotic adducts to proteins such as antibodies specific to an antigen
expressed on the surface of diseased epithelium are also discussed.
3
Closs, Patricia Souza. „Avaliação das condições de vida e saúde bucal de famílias da Comunidade Associação Social e Filantrópica Solar da Paz em Porto Velho- RO“. Universidade de Taubaté, 2008. http://www.bdtd.unitau.br/tedesimplificado/tde_busca/arquivo.php?codArquivo=495.
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O objetivo deste estudo tranversal foi avaliar as condições de saúde bucal, CPOD e doença periodontal, condições socioeconômicas, acesso e autopercepção em saúde bucal de população residente em comunidade periférica na cidade de Porto Velho, Rondônia. Os exames foram realizados por alunos de graduação de odontologia da Faculdade São Lucas. A calibração dos examinadores foi realizada através do Erro Padrão de Medida (EPM), obtendo-se valores dentro do limite de concordância aceitáveis de no mínimo 0,85 ou 85%. Foram avaliadas noventa e sete famílias de estudantes (460 indivíduos, 4,75 indivíduos por família) de uma creche em bairro
periférico. A avaliação socioeconômica mostrou que 70% das famílias estudadas ganhavam entre menos de um até dois salários mínimos, não recebiam água de Abastecimento Público, nem saneamento básico nem coleta de lixo pela Prefeitura; 73% ingeriram água de poço ou cacimba, 39% cloravam , 21% ferviam e 26% não faziam qualquer tratamento da água. Para o destino de dejetos, 91% utilizavam fossa Séptica. Os resultados referentes ao acesso aos serviços odotológicos mostrou que 30% dos indivíduos nunca foram ao dentista, 40% nunca receberam informação do profissional relacionados a prevenção, mas 70% consideraram necessitar de algum tipo de tratamento odontológico e 50% avaliaram o atendimento como péssimo e ruim. Para a avaliação da saúde bucal, a amostra foi dividida em cinco grupos de acordo com a idade: grupo A - zero a trinta e seis meses (ceo de 1, 33 ) Grupo B - quatro a seis anos ( ceo e CPOD de 5,21 e ISG 63%), Grupo C - onze a treze anos (CPOD 6, 61e CPI 43% dos indivíduos apresentaram algum tipo de alteração nos tecidos periodontais), Grupo D - quinze a dezenove anos (CPOD 9,76 e CPI apenas 33% apresentam o periodonto sadio), Grupo E de trinta e cinco a quarenta e quatro anos (CPOD de 21,63 e CPI quase 40% de sextantes foram excluídos e, no PIP, 15% dos sextantes apresentaram algum tipo de Perda de Inserção Periodontal), Grupo F sessenta e cinco a setenta e quatro anos(CPOD 27,71 e, em relação à Condição Periodontal, não foram analisados). O estudo concluiu que é necessário melhorar e reorganizar o acesso aos serviços de saúde do município, bem como implementar políticas de saúde bucal incluindo Fluoretação, envolvendo ações preventivas e restauradoras, garantindo assim condições melhores de saúde bucal da população estudada.This research is meant to evaluate, through a transversal study, caries and periodontal diseases, socioeconomic conditions, access and auto perception in oral health for peripheral area populations in the city of Porto Velho, Rondônia. The examinations were performed by Odontology Graduation Students at São Lucas Faculty. The calibration executed by the examiners was based on the Error Measure Standard (EMS), obtaining acceptable values inside the agreement limit of at least 0.85 or 85%. 97 families of a daycare center students have been evaluated, totaling 460 individuals. 4.75 individuals per family. The socioeconomic evaluation has shown that 70% of the studied families earned from less of one to two minimum salaries, they did not receive water from any public source, basic sanitation or garbage collection by the city hall; 73% used water for consumption from the well or cacimba, 39% used chlorine in it, 21% boiled it and 26% did not use any water treatment For the destination of the dejections, 91% had septic pools. The access to the odontologic services showed that 30% of the individuals had never been to the dentist, 40% had never received any information from the professional surgeon dentist on how to prevent oral problems, but 70% considered to need some type of odontologic treatment and 50% had evaluated the assistance as awful and bad. For the oral health evaluation, the sample was divided in 5 groups according to age: group A - from zero to 36 months (CEO 1.33 and AG 77%), group B 4 to 6 years (CEO and AG 5.21%), group C 11 to 13 years (CPOD 6.61 and CPI 43% of the individuals presented some kind of alteration in gum tissue), group D 15 to 19 years (CPOD 9.76 and CPI almost 40% from sextants were excluded and at PIP, 15% from the sextants presented any kind of periodontal insertion loss), group F 65 to 74 years (CPOD 27.71 and, in relation to periodontal condition, there were not enough sextants to be analyzed, for 79% of the sextants were excluded from the sample due to tooth loss). The study concluded that it is necessary to improve and to reorganize the city health services access, as well as to implement oral health policies like fluorine treatment involving preventing and restoring actions, guaranteeing better oral health conditions for the studied population.
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Chong, Adeline Yang Li. „The effects of chlorhexidine containing toothpastes and tea tree oil containing mouthwashes on plaque and gingival inflammation : a thesis submitted in partial fulfilment for the degree of Masters [sic] of Dental Surgery (Periodontics)“. Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09DM/09dmc548.pdf.
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Butze, Juliane Pereira. „Tratamento periodontal e manutenção periódica preventiva : avaliação longitudinal de tabagistas e não tabagistas“. reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/157502.
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Objetivo: Comparar a resposta ao tratamento entre pacientes tabagistas e não tabagistas e durante a fase de manutenção periódica preventiva (MPP), ao longo de 2 anos. Materiais e Métodos: Cinquenta e um pacientes com periodontite moderada a avançada, sendo 22 tabagistas (idade média de 48,3+8,1; 54,5% do sexo masculino; 6,4+5,2 dentes ausentes, tempo médio de exposição ao tabaco 21,6+11,4 anos, média de cigarros fumados ao dia 12,9+8,1) e 29 não tabagistas (idade média de 54,1+9,4; 69% do sexo masculino; 7,0+4,4 dentes ausentes) foram tratados de acordo com um protocolo não-cirúrgico. Finalizada a fase terapêutica, os pacientes iniciaram a fase de MPP. Exames periodontais, instrução de higiene bucal de acordo com as necessidades individuais, e as intervenções de manutenção foram realizadas em consultas trimestrais. Modelos de equações de estimativas generalizadas foram aplicados para avaliar o impacto do fumo na resposta ao tratamento periodontal e manutenção ao longo do tempo. Resultados: Não foram encontradas diferenças significativas em relação ao índice de placa (IP) entre tabagistas e não tabagistas, desde o exame basal até o último exame da fase de MPP (24 meses). O índice gengival comportou-se de forma semelhante ao de placa, sem diferenças entre tabagistas e não tabagistas ao longo do tratamento e da fase de MPP. O sangramento à sondagem (SS) diminuiu significantemente ao longo do tempo do estudo e uma maior diminuição ocorreu nas bolsas de PS de >6mm. A média de profundidade de sondagem (PS) para não tabagistas não apresentou diferença estatística entre os grupos, bem como a perda de inserção (PI). Conclusão: O presente estudo mostrou que o hábito do tabagismo não afetou a resposta ao tratamento periodontal e a manutenção dos resultados ao longo de 24 meses.Objective: To compare the effect to treatment of smokers and non-smokers during periodic preventive maintenance (MPP) over a period of 2 years. Materials and Methods: Fifty-one patients with moderate to advanced periodontitis, 22 smokers (mean age 48.3 + 8.1, 54.5% males, 6.4 + 5.2 missing teeth, mean time of tobacco smoking of 21.6 +11.4 years, mean of cigarettes smoked per day 12.9 +8.1) and 29 non-smokers (mean age of 54.1+9.4; 69% of males, 7.0+4.4 teeth missing) were treated according to a non-surgical protocol. After the therapeutic phase, the patients started the MPP phase. Periodontal examinations, oral hygiene instruction according to individual needs, and the interventions of MPP were carried out in quarterly consultations. Models of generalized estimation equations were applied to evaluate the impact of smoking on the response to periodontal treatment and maintenance over time. Results: There were no significant differences in the plaque index (PI) between smokers and non-smokers from baseline to the last exam of the MPP phase (24 months). Gingival index was similar to the plaque index, no differences between smokers and non-smokers throughout the treatment and MPP phase. Bleeding on probing (BOP) decreased significantly over the study time and a larger decrease occurred in probing depth (PD) pockets of > 6mm. The mean probing depth (PD) for non-smokers did not present statistical difference between groups, as well as clinical attachment level (CAL). Conclusion: The present study showed that the smoking habit did not affect the response to periodontal treatment and the maintenance of the results over the period of 24 months.
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Jaskulski, Ana Paula. „Resposta de molares e não molares a dois distintos protocolos de manutenção periódica preventiva : análise longitudinal“. reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/152687.
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Objetivos: o objetivo do presente estudo é avaliar a resposta molares e não molares a dois protocolos de atenção periodontal na fase de manutenção periódica preventiva (MPP). Métodos: Sessenta e dois pacientes com periodontite moderada ou avançada (idade média 50.97 ± 9.26 anos, 40 mulheres, 24 fumantes) foram tratados de acordo com um protocolo não-cirúrgico. Finalizada a fase terapêutica, os pacientes iniciaram a fase de MPP e foram randomicamente alocados para receber controle supragengival isolado (SPG) ou combinado ao subgengival (SPG+SBG). Exames periodontais, instruções de higiene bucal e as respectivas intervenções experimentais foram realizados em consultas trimestrais. Resultados: não foram observadas diferenças significativas nas variáveis demográficas, número médio de dentes e distribuição média de dentes não-molares/molares e de sítios livres/proximais entre os dois grupos experimentais. Quando do baseline, os dentes molares apresentaram um maior número de sítios positivos para IPV, ISG, SS e maiores valores médios de PS e PI quando comparados aos não-molares (p<0.001). Ao longo da fase de MPP, foi demonstrado que independente da terapia aplicada, tanto para molares e não molares, a resposta para ambos os grupos dentários não foi diferente. Da mesma forma, a perda dentária entre molares e não molares não diferiu ao longo de 24 meses. Conclusões: Molares apresentam semelhante resposta durante a fase de MPP quando comparados a dentes não molares, independente do protocolo de intervenção clínica aportado.Aim: The objective of the present study was to evaluate the response of molar teeth and non-molar teeth to two periodontal care protocols in the periodic preventive maintenance phase (PMP). METHODS: Sixty-two patients with moderate or advanced periodontitis (mean age 50.97 ± 9.26 years, 40 women, 24 smokers) were treated according to a non-surgical protocol. After the therapeutic phase, the patients started the PMP and were randomly assigned to receive supragingival (SPG) or combined subgengival (SPG + SBG) control. Periodontal examinations, oral hygiene instructions and the respective experimental interventions were performed in quarterly consultations. Results: There were no significant differences in demographic variables, mean number of teeth and mean distribution of non-molar / molar teeth and free / proximal sites between the two experimental groups. At the baseline, molar teeth had a higher number of positive sites for VPI, GBI, BOP and higher mean values of PPD and CAL when compared to non-molars (p <0.001). Throughout the MPP phase, it was demonstrated that regardless of the applied therapy, for both molars and non-molars, the response for both dental groups was not different. Likewise, tooth loss between molars and non-molars did not differ over 24 months. Conclusions: Molars presented a similar response during the PMP when compared to non-molar teeth, independent of the protocol of clinical intervention provided.
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Angst, Patrícia Daniela Melchiors. „Efeito do controle supragengival em comparação ao controle combinado supra e subgengival durante a fase de manutenção periódica preventiva : resultados microbiológicos“. reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/128798.
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Objetivos: Comparar o efeito do controle estrito do biofilme supragengival (SUPRA), em comparação ao controle combinado dos biofilmes supra e subgengival (SUPRA+SUB), na microbiota subgengival de pacientes durante a fase de manutenção periódica preventiva (MPP), ao longo de 1 ano. Materiais e métodos: Sessenta e dois pacientes com periodontite moderada ou avançada (idade média 50.97 ± 9.26 anos, 40 mulheres, 24 fumantes) foram tratados de acordo com um protocolo não-cirúrgico. Finalizada a fase terapêutica, os pacientes iniciaram a fase de MPP e foram randomicamente alocados para receber a intervenção SUPRA ou SUPRA+SUB. Exames periodontais, instruções de higiene bucal, e as respectivas intervenções (SUPRA ou SUPRA+SUB) foram realizados em consultas trimestrais. Biofilme subgengival foi coletado ao baseline, 3, 6 e 12 meses. Técnica de PCR em Tempo Real foi utilizada para quantificar as espécies bacterianas Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf), e o domínio Eubacteria (Bactérias totais). Equações de estimação generalizadas foram usadas para se estimar os efeitos dos tratamentos considerando-se a avaliação longitudinal. Resultados: Não foram observadas diferenças significativas entre os grupos para as contagens de Pg, Td, Tf, e Bactérias totais ao longo de 1 ano. Contudo, a partir dos 3 meses, as contagens de Pg e Tf aumentaram significativamente em ambos os grupos. As contagens de Bactérias totais e Td foram mantidas longitudinalmente. Por outro lado, as contagens médias das espécies bacterianas alvo permaneceram em baixos níveis (≤ 103) durante todo o estudo. Paralelamente, os parâmetros clínicos foram mantidos sem alterações significativas. Conclusões: As intervenções de manutenção investigadas produziram resultados microbiológicos semelhantes ao longo do tempo, o que demonstra o grande e importante impacto do controle do biofilme supragengival durante a fase de MPP.Aim: Compare the effects of supragingival scaling alone (SPG) against the combined supra and subgingival scaling (SPG+SBG), on subgingival microbiota from patients during periodontal maintenance period (PMP), along 1 year. Material and Methods: Sixty-two patients with moderate or severe periodontitis (mean age 50.97 ± 9.26, 40 females, 24 smokers) were treated according to a non-surgical protocol. Ended the therapy phase, they entered a PMP and were randomly allocated to receive SPG or SPG+SBG interventions. Periodontal exams, oral hygiene instructions, and the respective intervention (SPG or SPG+SBG) were performed at quarterly appointments. Subgingival biofilm was sampled at baseline, 3, 6 and 12 months. Real-time PCR technique was used to quantify the bacteria species Porphyromonas gingivalis (Pg), Treponema denticola (Td), Tannerella forsythia (Tf), and Eubacteria domain (Total bacteria). Generalized estimating equations were used to estimate treatment effects while accounting for longitudinal evaluation. Results: No significant inter-groups differences were observed to Pg, Td, Tf, and Total bacteria counts over 1 year. However, from 3 months onward, Pg and Tf counts increased significantly in both groups. Total bacteria and Td counts were maintained overtime. Still, the mean counts of target bacteria species remained at low levels (≤ 103) throughout the study. In parallel, the clinical parameters were maintained without significant changes. Conclusions: The PMP interventions yielded similar microbiological results along time, demonstrating the great impact and importance of supragingival biofilm control during PMP.
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Merces, Magno Concei??o das. „Periodontite e s?ndrome metab?lica: existe associa??o?“ Universidade Estadual de Feira de Santana, 2014. http://localhost:8080/tede/handle/tede/141.
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Introduction: Metabolic syndrome (MS ) has aroused interest in the health field, it is seen as the major factor for the occurrence of cardiovascular events . Causal factors associated with metabolic syndrome are not well defined and many unidentified. Still preliminary investigations suggest that infections may be involved in the causal chain of this syndrome. This study aimed to estimate the association between periodontal infection, presence of periodontitis and the diagnosis of metabolic syndrome. Methods: A cross-sectional study was conducted with 419 participants. After application of a questionnaire, general and oral clinical examination and data collection laboratory test, the diagnosis of periodontitis and metabolic syndrome were performed. The magnitude of the association between periodontitis and diagnosis of metabolic syndrome was expressed by the prevalence ratio (PR) and a confidence interval of 95 % ( 95 % CI ). The analysis of the effect of periodontitis on metabolic syndrome the multivariate Poisson regression with robust variance was applied. Results: The findings of this study were presented in a paper to be published in the Journal of Periodontology. There was no association between periodontitis and metabolic syndrome in two models of analysis performed according to the diagnosis of the syndrome, RPajustada1 = 1.01, 95% CI [ 0.75 to 1.34 ] , p = 0.97 and RPajustada2 = 0 95 , 95% CI [ 0.72 to 1.26 ] , p = 0.74 , even after adjusting for sex, age, education level, and smoking. Conclusions: periodontitis was not an independent factor for SM.
Introdu??o: A s?ndrome metab?lica (SM) tem despertado interesse no campo da sa?de, vez que ? apontada como fator preponderante para a ocorr?ncia de eventos cardiovasculares. Os fatores causais relacionados ? s?ndrome metab?lica ainda n?o est?o bem definidos e muitos, n?o identificados. Investiga??es ainda incipientes sugerem que infec??es podem estar envolvidas na cadeia causal desta s?ndrome. Esse estudo teve por objetivo estimar a associa??o entre a infec??o periodontal ?periodontite - e o diagn?stico de s?ndrome metab?lica. M?todos: Um estudo transversal foi realizado com 419 participantes. Ap?s a aplica??o de um question?rio, exame cl?nico geral e bucal, e coleta de dados de exame de laborat?rio, o diagn?stico de periodontite e s?ndrome metab?lica foram realizados. A magnitude da associa??o entre a presen?a de periodontite e diagn?stico de s?ndrome metab?lica foi expressa pela Raz?o de Preval?ncia (RP) e intervalo de confian?a de 95% (IC 95%). O efeito da periodontite na s?ndrome metab?lica foi analisado com o emprego de modelo multivariada de Poisson com vari?ncia robusta. Resultados: Os achados do presente estudo foram apresentados em forma de artigo a ser publicado no peri?dico Journal of Periodontology. N?o houve associa??o entre periodontite e SM nos dois modelos de an?lise realizados de acordo com o diagn?stico da s?ndrome, RPajustada1 = 1,01, IC95% [0,75 ? 1,34], p=0,97 e (RPajustada2 = 0,95, IC95% [0,72 ? 1,26], p=0,74, mesmo ajustada para sexo, idade, n?vel de escolaridade e h?bito de fumar. Conclus?es: A periodontite n?o se mostrou um fator independente ? SM.
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Stadler, Amanda Finger. „Avaliação imunológica de duas sistemáticas de atenção periodontal na fase de manutenção periódica preventiva : análise secundária de uma subamostra de um ensaio clínico randomizado“. reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/128194.
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Introdução: A necessidade de pacientes serem inseridos em protocolos de manutenção periodontais (PMP) após tratamento periodontal é bem estabelecida na literatura. No entanto, ainda não é bem estabelecido quais procedimentos são necessários para manter a saúde periodontal. O objetivo do presente estudo foi identificar quais os biomarcadores relacionados com a doença periodontal e comparar o efeito de dois PMPs nos níveis destes biomarcadores pró e antiinflamatórios do fluido crevicular gengival (FCG) durante 1 ano. Materiais e Métodos: Após o tratamento periodontal não-cirúrgico, 34 sujeitos (14H/20M, idade média 54 anos) diagnosticados com periodontite crônica foram randomicamente alocados em um dos seguintes grupos: a) somente raspagem supragingival; b) raspagem supra e subgengival. Todos os participantes receberam instruções de higiene oral personalizados e polimento dos dentes. Os indivíduos foram vistos em intervalos de três meses para a realização de exames clínicos, coleta de FCG e procedimentos de manutenção periodontal. As principais citocinas pró- e anti-inflamatórias e quimiocina relacionadas com a doença periodontal foram identificadas por meio de uma revisão sistemática da literatura com metanálise. Em seguida, os níveis de FCG de 16 citocinas e quimiocinas dos 34 sujeitos incluídos no estudo foram medidos por meio de um imunoensaio múltiplo. Resultados: Não foram observadas diferenças significativas nos parâmetros clínicos ou imunológicos entre os dois PMPs. Os níveis médios de concentração no FCG da maioria das citocinas pró-inflamatórias foram geralmente baixos / moderados durante todo o período de estudo, com exceção da IL-1β. Os níveis das citocinas anti-inflamatórias IL-4 e IL-13 foram moderado / alto. Entre as quimiocinas, os níveis de MIP-1α e MCP-1 foram altos, e a concentração de IL-8 foi muito alta durante todo o estudo. Conclusões: Os resultados sugerem que um PMP baseado apenas no controle do biofilme supragengival é tão eficaz na manutenção de baixos níveis de inflamação periodontal e estabilidade clínica após o tratamento quanto um PMP baseado em controle supra e subgengival.Introduction: The need for patients to be enrolled into periodontal maintenance protocols (PMP) after periodontal treatment is well established in the literature. However, it is still unknown which interventions are necessary to maintain periodontal health. The aim of the present study was to identify the biomarkers related to periodontal disease, and to compare the 1-year effect of two periodontal maintenance protocols (PMP) on gingival crevicular fluid (GCF) levels of pro- and anti-inflammatory biomarkers. Material and Methods: Following non-surgical periodontal treatment, 34 subjects (14M/20F, mean age: 54 years) diagnosed with chronic periodontitis were randomly assigned into one of the following study arms: a) supragingival scaling only; b) supra and subgingival scaling. All subjects received personalized oral hygiene instructions and tooth polishing. Subjects were seen at 3 months intervals for periodontal maintenance, clinical data and GCF collection. The major pro-and anti-inflammatory cytokines and chemokine related to periodontal disease were identified through a systematic review of the literature with metaanalysis. After that, GCF levels of 16 different cytokines and chemokines from the 34 subjects included in the study were measured using a multiplex immunoassay. Results: No significant differences between PMPs were observed for any clinical parameters or immunological biomarkers. Median GCF concentration levels for most pro-inflammatory cytokines were generally low/moderate throughout the study period, with the exception of IL-1β. GCF levels of anti-inflammatory cytokines IL-4 and IL-13 were moderate/high. For chemokines, GCF levels for MIP-1α and MCP-1 were high, and concentration for IL-8 was very high. Conclusion: Our findings suggest that a PMP based on supragingival biofilm control alone is as effective in maintaining low levels of periodontal inflammation and clinical stability after treatment as a PMP based on combined supra/subgingival biofilm control.
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Santos, Bruna Rafaela Martins dos. „Preval?ncia e susceptibilidade antimicrobiana de Staphylococcusspp. em quadros de sa?de e doen?a periodontal“. Universidade Federal do Rio Grande do Norte, 2007. http://repositorio.ufrn.br:8080/jspui/handle/123456789/17094.
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The aim of this study was determine the prevalence and antimicrobial susceptibility of Staphylococcus spp. from patients with periodontal disease and periodontally healthy, correlate them with factors to host, local environment and traits of the diseases. To this, thirty adults from 19 to 55 years old were selected. They had not periodontal treatment and no antibiotic or antimicrobial was administered during three previous months. From these individuals, sites periodontally healthy, with chronic gingivitis and/or periodontitis were analyzed. Eighteen subgingival dental biofilm samples were collected through sterile paper points being six from each tooth randomly selected, representing conditions mentioned. They were transported to Oral Microbiology laboratory, plated onto Mannitol Salt Agar (MSA) and incubated at 370C in air for 48 h. Staphylococcus spp. were identified by colonial morphology, Gram stain, catalase reaction, susceptibility to bacitracin and coagulase activity. After identification, strains were submitted to the antibiotic susceptibility test with 12 antimicrobials, based on Kirby-Bauer technique. To establish the relation between coagulase-negative Staphylococcus (CSN) presence and their infection levels and host factors, local environment and traits of diseases were used Chi-square, Mann-Whitney and Kruskal-Wallis tests to a confidence level of 95%. 86,7% subjects harbored CSN in 11,7% periodontal sites. These prevalence were 12,1% in healthy sites, 11,7% in chronic gingivitis, 13,5% in slight chronic periodontitis, 6,75% in moderate chronic periodontitis and in sites with advance chronic periodontitis was not isolated CSN, without difference among them (p = 0,672). There was no significant difference to presence and infection levels of CSN as related to host factors, local environm ent and traits of the diseases. Amongst the 74 samples of CSN isolated, the biggest resistance was observed to penicillin (55,4%), erythromycin (32,4%), tetracycline (12,16%) and clindamycin (9,4%). 5,3% of the isolates were resistant to oxacilin and methicillin. No resistance was observed to ciprofloxacin, rifampicin and vancomycin. It was concluded that staphylococci are found in low numbers in healthy or sick periodontal sites in a similar ratio. However, a trend was observed to a reduction in staphylococci occurrence toward more advanced stages of the disease. This low prevalence was not related to any variables analyzed. Susceptibility profile to antibiotics demonstrates a raised resistance to penicillin and a low one to methicillin. To erythromycin, tetracycline and clindamycin was observed a significant resistance
O objetivo deste estudo foi determinar a preval?ncia e a susceptibilidade antimicrobiana de Staphylococcus spp. em quadros de sa?de e doen?a periodontal, relacionando-as com fatores do hospedeiro, do meio ambiente local e pr?prios das doen?as. Para tanto, foram selecionados 30 indiv?duos adultos, entre 19 e 55 anos, que apresentassem s?tios periodontais saud?veis, com gengivite cr?nica e/ou periodontite cr?nica, sem tratamento periodontal, e que n?o tivessem usado antibi?tico ou antimicrobiano nos ?ltimos tr?s meses. De cada paciente foram coletadas 18 amostras de biofilme subgengival, sendo 6 por elemento dent?rio sorteado com as condi??es supracitadas. Com o aux?lio de pontas de papel absorventes est?reis, tais amostras foram coletadas do sulco gengival ou bolsa periodontal, semeadas em Agar Manitol Salgado e incubadas a 370C por 48 horas. A identifica??o de Staphylococcus spp. se deu atrav?s da colora??o de Gram, prova da catalase, susceptibilidade ? bacitracina e prova da coagulase livre Ap?s a identifica??o, as amostras foram submetidas ao teste de susceptibilidade a doze antimicrobianos, atrav?s da t?cnica de Kirby-Bauer. Para o estabelecimento da rela??o entre a presen?a de estafilococos coagulase-negativos, os n?veis de infec??o dos mesmos e os fatores do hospedeiro, do meio ambiente local e pr?prios das doen?as, foram usados os testes do Quiquadrado, Mann-Whitney e Kruskal-Wallis para um n?vel de confian?a de 95%. Quanto ? preval?ncia de estafilococos coagulase-negativos, 86,7% dos indiv?duos albergavam este microrganismo em 11,7% dos s?tios periodontais, sendo distribu?dos em 12,1% entre os saud?veis, 11,7% com gengivite cr?nica, 13,5% com periodontite cr?nica leve, 6,75% com periodontite cr?nica moderada e nenhum s?tio com periodontite cr?nica severa (p=0,672). N?o houve associa??o significativa na freq??ncia de isolamento ou nos n?veis de infec??o de ECN com fatores do hospedeiro, do meio ambiente local e pr?prios das doen?as. Dentre as 74 cepas isoladas de ECN, a maior resist?ncia observada neste estudo foi ? penicilina (55,4%), eritromicina (32,4%), tetraciclina (12,16%) e clindamicina (9,4%). Cinco v?rgula tr?s por cento das cepas foram resistentes ? oxacilina e ? meticilina. Nenhuma cepa apresentou resist?ncia aos antibi?ticos ciprofloxacina, rifampicina e vancomicina. Conclui-se, portanto, que os estafilococos est?o presentes em baixos n?meros em s?tios periodontais saud?veis e doentes numa propor??o equivalente. Por?m, uma tend?ncia foi observada em rela??o ao decr?scimo de sua ocorr?ncia em quadros mais avan?ados da doen?a periodontal. Essa baixa preval?ncia de SCN n?o esteve associada a nenhum a das vari?veis testadas nesse estudo. O perfil de susceptibilidade aos antimicrobianos demonstrou um a elevada resist?ncia ? penicilina, por?m uma baixa resist?ncia ? meticilina. Para a eritromicina, tetraciclina e clindamicina foi encontrada uma resist?ncia significativa
Bücher zum Thema "Periodontitis Prevention"
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Periodontitis: Symptoms, treatment, and prevention. Hauppauge, N.Y: Nova Science Publisher's, 2010.
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Dag, Ørstavik, und Pitt Ford T. R, Hrsg. Essential endodontology: Prevention and treatment of apical periodontitis. Oxford, OX: Blackwell Science, 1998.
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3
Gmür, Rudolf. Value of new serological probes for the study of putative periodontal pathogens: A survey after five years of application. Chicago: Quintessence Pub. Co., 1995.
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4
Saadoun, Andre P. Esthetic soft tissue management of teeth and implants. Chichester, West Sussex: John Wiley & Sons, 2013.
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5
Prevention and Treatment of Periodontitis. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-0365-1325-6.
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Heikkinen, Anna Maria, H. S. Mbawala, Ana Pejcic und Hisashi Fujita. Periodontitis: Diagnosis, Prevention and Treatment. DI Press, 2022.
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Dag, Ørstavik, und Pitt Ford T. R, Hrsg. Essential endodontology: Prevention and treatment of apical periodontitis. 2. Aufl. Oxford, UK: Blackwell Munksgaard, 2008.
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Essential Endodontology: Prevention and Treatment of Apical Periodontitis. 2. Aufl. Wiley-Blackwell, 2007.
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Leung, Wai-Keung. Periodontitis: Symptoms, Prevention and Treatment Options. Nova Science Publishers, Incorporated, 2019.
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Orstavik, Dag, und Thomas R. Pitt Ford. Essential Endodontology: Prevention and Treatment of Apical Periodontitis. Blackwell Publishing Limited, 1998.
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1
Garaicoa-Pazmino, Carlos, Ann M. Decker und Peter J. Polverini. „Personalized Medicine Approaches to the Prevention, Diagnosis, and Treatment of Chronic Periodontitis“. In Personalized Oral Health Care, 99–112. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-23297-3_8.
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Krishna, Ranjitha, Philip J. Hanes und Christopher W. Cutler. „Understanding Inflammation: The Key to Targeted Preventive Measures for Diabetes and Periodontitis“. In New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM, 323–53. Dordrecht: Springer Netherlands, 2013. http://dx.doi.org/10.1007/978-94-007-5971-8_12.
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N. Alawaji, Yasmine. „Periodontitis, Its Associations, and Prevention“. In Dentistry. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.109015.
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The ultimate goal of studying associations with diseases is to plan, implement, and evaluate preventive strategies. Today, after reviewing the body of evidence, one needs to ask: What has not been learned yet regarding periodontitis associations and its prevention? Current recommendations to prevent periodontitis are mostly limited to individual patient care while population-based approaches are nearly absent. Current strategies are not only time-consuming and costly but can be also ineffective to combat disease burden in populations. To initiate and sustain successful outcomes, prevention needs to be applied at multiple levels. Interventions need to target unhealthy behaviors along with their associated social and physical environmental constraints. The chapter presents highlights from current research on associations with periodontitis, its limitations, and the need to understand pathways linking periodontitis with its exposures over the life course. Finally, a suggested multilevel strategy for periodontitis prevention was outlined.
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„Prevention—Prophylaxis: Dentistry: Caries, Gingivitis, Periodontitis“. In Color Atlas of Dental Hygiene: Periodontology, herausgegeben von Herbert F. Wolf und Thomas M. Hassell. Stuttgart: Georg Thieme Verlag, 2006. http://dx.doi.org/10.1055/b-0034-56514.
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Daly, Blánaid, Paul Batchelor, Elizabeth Treasure und Richard Watt. „Prevention of periodontal diseases“. In Essential Dental Public Health. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199679379.003.0019.
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During the last 20 years our understanding of periodontal disease has been dramatically changed. Findings from clinical and epidemiological research have challenged the traditional progressive disease model and questioned the extent of destructive periodontal diseases within the population (Baleum and Lopez 2003; Petersen and Ogawa 2005; Sheiham and Netuveli 2002). Although gaps in our knowledge still exist about the precise nature and full extent of the condition, it is critically important that preventive and public health approaches to periodontal disease are based upon current scientific understanding of the condition (Baleum and Lopez 2003). This chapter will present an overview of current clinical and epidemiological research findings on periodontal disease. This will be followed by a critical review of the various options for prevention of the condition, with particular emphasis on the public health strategies required. Before considering the options for the prevention of periodontal diseases it is important to highlight the main epidemiological features of the condition. Although most adults have some gingivitis and calculus deposits, epidemiological surveys indicate that only approximately 10–15% of the adult population suffer from progressive periodontitis (Albandar 2005; Papapanou 1999; Petersen and Ogawa 2005; Sheiham and Netuveli 2002). The extent and severity of periodontitis increases with age and is more common among men than women. Stark socioeconomic inequalities exist, with lower-income and less-educated groups having significantly worse periodontal health than their more affluent and educated contemporaries (Petersen and Ogawa 2005; Sheiham and Netuveli 2002). As with other chronic diseases, a consistent social gradient exists in the distribution of periodontal diseases within a defined population (Borrell et al. 2006; Lopez et al 2006; Sabbah et al. 2007). The social gradient indicates that socio-economic differences in periodontal measures do not just occur at the extremes of the social spectrum between the rich and poor in society, but across the entire social hierarchy in a graded stepwise fashion. Trend data suggest that in high- and middle-income countries, oral hygiene levels have steadily improved in all age groups and there has been a decline in the extent of gingivitis (Hugoson et al 1998; Morris et al. 2001).
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„Restorative dentistry 1: periodontology“. In Oxford Handbook of Clinical Dentistry, herausgegeben von Bethany Rushworth und Anastasios Kanatas, 173–224. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198832171.003.0005.
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This chapter covers the fundamentals of the diagnosis, prevention, and treatment of periodontal disease, alongside the most recent classification system. The epidemiology of periodontal disease is discussed before the key aspects of clinical examination are explained. The relevance and implications of plaque and calculus are detailed including their composition and pathological effects. The chapter includes the clinical features of periodontal diseases, including aggressive periodontitis, necrotizing periodontal diseases, and periodontal abscesses, as well as periodontitis associated with endodontic lesions. The principles of periodontal surgery are described, covering local anaesthetic techniques, flap design, and suturing techniques, as well as regenerative techniques and mucogingival surgery.
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Lynn Harney, Tracey. „Trans-Resveratrol: From Phytonutrient Supplement, to Novel Nanotherapeutic Agent“. In Dentistry. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108496.
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Trans-resveratrol (3,5,4′-trihydroxy-trans-stilbene) (RES) is a plant polyphenol that has been well documented for its anti-oxidant, antimicrobial, anti-inflammatory, and anti-aging properties. Moreover, compelling evidence presented in the abundance of pre-clinical studies using ligature-induced periodontitis models has positioned RES as a theoretically viable candidate for the reduction of the chronic inflammation, oxidative stress, and tissue destruction seen in periodontitis (PD). However, the instability of RES under physiological conditions, as well as its rapid hepatic clearance, has presented as a challenge to its ubiquitous application as an oral therapeutic in clinical practice. Fortunately, with the application of nanotechnology, the pharmacological profile of RES repositions the phytochemical from an herb-based supplement, useful as an adjunct therapy, to a stable and potent nanomedicine, demonstrating efficacy for the prevention and treatment of PD and its associated systemic diseases. This chapter explores the details of the potential for nano-RES as a viable therapeutic for PD.
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Fabiola Díaz-García, Irma, Dinorah Munira Hernández-Santos, Julio Alberto Díaz-Ramos und Neyda Ma. Mendoza-Ruvalcaba. „Oral Health and Prevention in Older Adults“. In Oral Health Care [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.101043.
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The most prevalent oral diseases such as tooth decay and chronic periodontitis, are the main responsible for tooth loss, this causes a disability in the chewing function, which alters the selection of food, the pleasure of eating, and the state of nutrition. Even the use of total prostheses to replace this loss is not always satisfactory. In the emotional sphere, poor oral health causes discomfort and a decrease in self-esteem. Unfortunately, this continues to occur in older people despite the great scientific and technological advances in dentistry today. Health promotion, which includes health education and prevention, must be present in the course of people’s lives. In the prevention of oral diseases, consider not only biological factors as the only causes, but also alleviate and modify the social determinants of the disease. All those involved in the care of the older adults must promote prevention as the most important tool in favor of oral health, and make older people enjoy life with quality. Oral health is an invaluable asset and reward at this stage of life.
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S. Natto, Zuhair. „Herbs and Oral Health“. In Oral Health Care [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.103715.
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Herbal medicine has long been used to prevent and control disease, and it can minimize the potential side effects of chemical products. However, side effects from herbs do exist. Most of the challenges with herbal medicine revolves around inadequate information about the effect of herbs in the oral cavity, the mechanism of action, and potential side effects. There are several herbs described in this chapter have anti-inflammatory, anti-bacterial, anti-viral, anti-fungal in oral micro-organisms. It includes aloe vera, ginger, clove, cinnamon, garlic, neem, miswak, turmeric, tulsi, green tea, chamomile, fenugreek, anise plant, peppermint, bloodroot, caraway, eucalyptus, phyllanthus emblica, black seed, myrrh, rosemary, sage, and thyme; some may act as an alternative management option to current treatments for oral conditions such as caries prevention, gingivitis, periodontitis, oral burn, ulcers and inflammation, after extraction, dry mouth, pain reduction, anesthesia, intracanal medications, ill-fitting dentures, peri-implant mucositis and peri-implantitis. It can be used in several forms such as mouthwashes, toothpastes, topical agents or local drug delivery devices. However, more research is needed to understand their mechanisms and potential side effects.
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Roman, Alexandra, Andrada Soancă, Bogdan Caloian, Alexandru Bucur, Gabriela Valentina Caracostea, Andreia Paraschiva Preda, Dora Maria Popescu et al. „Periodontitis and Heart Disease: Current Perspectives on the Associative Relationships and Preventive Impact“. In Oral Health Care [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102669.
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Due to the important advancement and the accumulation of new evidence on the periodontitis-cardiovascular disease (CVD) relationship as well as the major medical, economic and social burden caused by both diseases this chapter aims to review existing epidemiological and pathogenetic links related to this topic. Also, this chapter aims to highlight the impact of the periodontitis-CVD relationships on clinical practice and on the preventive approaches targeting to decrease the impact of periodontitis on CVD. Periodontitis is an infectious disease eliciting local and general inflammation, which leads to periodontal destruction and systemic involvement. Several pathways could explain the link between periodontitis and CVD such as bacteraemia, chronic persistent systemic inflammation and oxidative stress. The first step in the treatment of periodontitis addresses the elimination of microbial components, which lead to a decrease in local and systemic inflammation. Periodontal therapy seems to positively impact CVD. Specialists should inform patients with CVD on the negative impact of periodontitis on their systemic status and refer patients to the periodontist for an extensive examination as routine management of CVD. Some possible risks of periodontal therapy should be considered in patients undergoing antithrombotic medication.
Konferenzberichte zum Thema "Periodontitis Prevention"
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Иманов, Э. А. „Использование современных препаратов в комплексном лечении и профилактика воспалительных заболеваний пародонта у детей“. In Наука России: Цели и задачи. НИЦ "LJournal", 2021. http://dx.doi.org/10.18411/sr-10-06-2021-04.
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In the study process participated schoolсhildren with diagnosis of chronic catarrhal gingivitis (HKG) and chronic periodontitis light form (HPLC). In total 103 patient, 67 patient with chronic catarrhal gingivitis and 36 patient with chro nic periodontitis light form. The laboratory results showed that in the process of conducting treatment and preventive measures during the use of the drug Loroben the functional activity of the local immune factors were significantly restored. If we pay attention to indicators after professional hygiene and local application of a solution of digluconate of chlorhexidine, after treatment with Loroben values significantly increased . Solution of Loroben improves trophic of the periodontal tissues, promotes the elimination of bleeding gums and inflammation, and these promotes positive treatment outcome.