Auswahl der wissenschaftlichen Literatur zum Thema „Otogl“

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Zeitschriftenartikel zum Thema "Otogl"

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Oonk, Anne M. M., Joop M. Leijendeckers, Patrick L. M. Huygen, Margit Schraders, Miguel del Campo, Ignacio del Castillo, Mustafa Tekin et al. „Similar Phenotypes Caused by Mutations in OTOG and OTOGL“. Ear and Hearing 35, Nr. 3 (2014): e84-e91. http://dx.doi.org/10.1097/aud.0000000000000008.

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Dubaissi, Eamon, Karine Rousseau, Gareth W. Hughes, Caroline Ridley, Richard K. Grencis, Ian S. Roberts und David J. Thornton. „Functional characterization of the mucus barrier on the Xenopus tropicalis skin surface“. Proceedings of the National Academy of Sciences 115, Nr. 4 (08.01.2018): 726–31. http://dx.doi.org/10.1073/pnas.1713539115.

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Mucosal surfaces represent critical routes for entry and exit of pathogens. As such, animals have evolved strategies to combat infection at these sites, in particular the production of mucus to prevent attachment and to promote subsequent movement of the mucus/microbe away from the underlying epithelial surface. Using biochemical, biophysical, and infection studies, we have investigated the host protective properties of the skin mucus barrier of the Xenopus tropicalis tadpole. Specifically, we have characterized the major structural component of the barrier and shown that it is a mucin glycoprotein (Otogelin-like or Otogl) with similar sequence, domain organization, and structural properties to human gel-forming mucins. This mucin forms the structural basis of a surface barrier (∼6 μm thick), which is depleted through knockdown of Otogl. Crucially, Otogl knockdown leads to susceptibility to infection by the opportunistic pathogen Aeromonas hydrophila. To more accurately reflect its structure, tissue localization, and function, we have renamed Otogl as Xenopus Skin Mucin, or MucXS. Our findings characterize an accessible and tractable model system to define mucus barrier function and host–microbe interactions.
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Barake, Rana, Samer Abou-Rizk, Georges Nemer und Marc Bassim. „The OTOGL p.Arg925* Variant is Associated with Moderate Hearing Loss in a Syrian Nonconsanguineous Family“. Genetic Testing and Molecular Biomarkers 21, Nr. 7 (Juli 2017): 445–49. http://dx.doi.org/10.1089/gtmb.2016.0406.

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Yariz, Kemal O., Duygu Duman, Celia Zazo Seco, Julia Dallman, Mingqian Huang, Theo A. Peters, Asli Sirmaci et al. „Mutations in OTOGL , Encoding the Inner Ear Protein Otogelin-like, Cause Moderate Sensorineural Hearing Loss“. American Journal of Human Genetics 91, Nr. 5 (November 2012): 872–82. http://dx.doi.org/10.1016/j.ajhg.2012.09.011.

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Gu, Xiaodong, Shan Sun, Luo Guo, Xiaoling Lu, Honglin Mei, Chuijin Lai und Huawei Li. „Novel biallelic OTOGL mutations in a Chinese family with moderate non-syndromic sensorineural hearing loss“. International Journal of Pediatric Otorhinolaryngology 79, Nr. 6 (Juni 2015): 817–20. http://dx.doi.org/10.1016/j.ijporl.2015.03.008.

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Colciago, Alessandra, Matteo Audano, Veronica Bonalume, Valentina Melfi, Tasnim Mohamed, Adam J. Reid, Alessandro Faroni, Peter A. Greer, Nico Mitro und Valerio Magnaghi. „Transcriptomic Profile Reveals Deregulation of Hearing-Loss Related Genes in Vestibular Schwannoma Cells Following Electromagnetic Field Exposure“. Cells 10, Nr. 7 (20.07.2021): 1840. http://dx.doi.org/10.3390/cells10071840.

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Hearing loss (HL) is the most common sensory disorder in the world population. One common cause of HL is the presence of vestibular schwannoma (VS), a benign tumor of the VIII cranial nerve, arising from Schwann cell (SC) transformation. In the last decade, the increasing incidence of VS has been correlated to electromagnetic field (EMF) exposure, which might be considered a pathogenic cause of VS development and HL. Here, we explore the molecular mechanisms underlying the biologic changes of human SCs and/or their oncogenic transformation following EMF exposure. Through NGS technology and RNA-Seq transcriptomic analysis, we investigated the genomic profile and the differential display of HL-related genes after chronic EMF. We found that chronic EMF exposure modified the cell proliferation, in parallel with intracellular signaling and metabolic pathways changes, mostly related to translation and mitochondrial activities. Importantly, the expression of HL-related genes such as NEFL, TPRN, OTOGL, GJB2, and REST appeared to be deregulated in chronic EMF exposure. In conclusion, we suggest that, at a preclinical stage, EMF exposure might promote the transformation of VS cells and contribute to HL.
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Pan, Chen, Jun Li, Shixin Wang, Chen Shi, Yunmei Zhang und Yafeng Yu. „Novel heterozygous mutations in the otogelin-like (OTOGL) gene in a child with bilateral mild nonsyndromic sensorineural hearing loss“. Gene 808 (Januar 2022): 146000. http://dx.doi.org/10.1016/j.gene.2021.146000.

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Bonnet, C., M. Louha, N. Loundon, N. Michalski, E. Verpy, L. Smagghe, J. P. Hardelin et al. „Biallelic nonsense mutations in the otogelin-like gene (OTOGL) in a child affected by mild to moderate hearing impairment“. Gene 527, Nr. 2 (September 2013): 537–40. http://dx.doi.org/10.1016/j.gene.2013.06.044.

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Uran, Erik, Luka Fotović, Nikola Bedeković, Vladimir Stilinović und Dominik Cinčić. „The Amine Group as Halogen Bond Acceptor in Cocrystals of Aromatic Diamines and Perfluorinated Iodobenzenes“. Crystals 11, Nr. 5 (11.05.2021): 529. http://dx.doi.org/10.3390/cryst11050529.

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In order to study the proclivity of primary amine groups to act as halogen bond acceptors, three aromatic diamines (p-phenylenediamine (pphda), benzidine (bnzd) and o-tolidine (otol)) were cocrystallised with three perfluorinated iodobenzenes (1,4-tetrafluorodiiodobenzene (14tfib), 1,3-tetrafluorodiiodobenzene (13tfib) and 1,3,5-trifluorotriiodobenzene (135tfib)) as halogen bond donors. Five cocrystals were obtained: (pphda)(14tfib), (bnzd)(13tfib)2, (bnzd)(135tfib)4, (otol)(14tfib) and (otol)(135tfib)2. In spite of the variability of both stoichiometries and structures of the cocrystals, in all the prepared cocrystals the amine groups form exclusively I···N halogen bonds, while the amine hydrogen atoms participate mostly in N–H⋯F contacts. The preference of the amine nitrogen atom toward the halogen bond, as opposed to the hydrogen bond (with amine as a donor), is rationalised by means of computed hydrogen and halogen bond energies, indicating that the halogen bond energy between a simple primary amine (methylamine) and a perfluorinated iodobenzene (pentafluoroiodobenze ne) is ca. 15 kJ mol−1 higher than the energy of the (H)NH∙∙∙NH2 hydrogen bond between two amine molecules.
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Skord, Virginia, und Barbara Ruch. „Mo Hitotsu no Chuseizo: Bikuni, Otogi Zoshi, Raisei.“ Monumenta Nipponica 47, Nr. 3 (1992): 393. http://dx.doi.org/10.2307/2385107.

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Dissertationen zum Thema "Otogl"

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Nagaike, Kazumi. „Dazai Osamu's Otogi zoshi, a structural and narratological analysis“. Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq22546.pdf.

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Reeves, David. „A Brief Introduction to Aoki Rosui and Annotated Translation of his Text Otogi Hyaku Monogatari“. 2015. https://scholarworks.umass.edu/masters_theses_2/240.

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The world of Japanese literature spans a vast number of genres and media, so much that while it makes sense that English speaking academia is unaware of many prolific and influential authors and works, it might be surprising that some of those same people and publications are not well studied in their original language. Even though this is common among many languages, older Japanese texts have the added challenge of a variant grammar structure and writing style that forces scholars to be aware of the differences in the classical variation of the language. To that end, the author named Aoki Rosui may not be a household name within many circles of Japanese literary study. Still, extensive study of the horror stories known as kaidan and hyaku monogatari as well as Edo period Japanese literature as a whole is incomplete without knowing of his life and his contribution entitled Otogi hyaku monogatari. By gaining a rudimentary knowledge of the man behind this collection of ghost tales, as well as the people who exerted a significant influence on him, his reasons and methods taken in writing his collection of stories can be explored. At the same time, the classification of certain types of media into conventions known as genres is a very ambiguous field. Working through a variety of genres, both specific to Japan and general, will reveal the sheer variety that the kaidan category allows the author to explore. Preceding the annotated translation of a selection of Otogi hyaku monogatari will be a brief introduction and analysis of each of the stories that have been selected, using various references as support for the types of mythological and historical icons contained within them. Finally, I will present how I went about translating the preface and five stories with a brief discussion on translation methods before presenting the English version of the Japanese text.
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Blum, Haley R. „Flowers, Trees, and Writing Brushes: Extraordinary Lovers in the Otogi-zoshi Kazashi no Himegimi and Sakuraume no Soshi“. 2013. https://scholarworks.umass.edu/theses/1109.

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This thesis presents translations of Kazashi no himegimi and Sakuraume no sōshi, two tales belonging to the genre of medieval Japanese narrative known as otogi-zōshi, and of the subcategory known as iruimono (tales of non-humans). Chapter 1 provides context, beginning with a brief history of otogi-zōshi and a description of residual challenges in its research, including the parameters of the genre and problems with its nomenclature. This is followed by a discussion of the typical physical formats of these tales, Nara ehon and emaki, and a brief history of iruimono and plant symbolism in otogi-zōshi completes the chapter. Literary analysis of Kazashi no himegimi and Sakuraume no sōshi in Chapter 2 focuses on the irui characters in each tale, describing their motivations and the effect they have on the humans they interact with. Format, plot, and character are compared and contrasted for each tale, and the textual sources are briefly described. Chapter 3 provides complete translations for Kazashi no himegimi and Sakuraume no sōshi with annotations for obscure words, puns, and meanings that may be unclear in the text. The chapter ends with a conclusion discussing aspects of the tales that might usefully be explored further.
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Bücher zum Thema "Otogl"

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Otogi-zōshi. Tōkyō: Chūō Kōron Shinsha, 2000.

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Adrienne, Beck, und Alexander Jim O, Hrsg. Otogi zoshi. Los Angeles, CA: Tokyopop, 2006.

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Kōtsuki, Akimi. Otogi-zōshi. Tōkyō: Kumon Shuppan, 1993.

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Otogi-zōshi. Tōkyō: Iwanami Shoten, 2014.

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Nihon Bungaku Kenkyū Shiryō Kankōkai., Hrsg. Otogi-zōshi. Tōkyō: Yūseidō, 1985.

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Dazai, Osamu. Otogi-zōshi. Tōkyō: Nihon Kindai Bungakukan, 1992.

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Matsumoto, Ryūshin. Otogi sōshishū. Tōkyō: Shinchōsha, 2020.

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Hoshi, Shin'ichi. Nokku no otoga. Tōkyō: Shinchōsa, 1985.

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Kazuyoshi, Fujikake, und Tsukahara Kiyoshi, Hrsg. Otogi-zōshi sōsakuin. Tōkyō: Kasama Shoin, 1988.

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Tsukahara, Kiyoshi. Otogi-zōshi sōsakuin. Tōkyō: Kasama Shoin, 1988.

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Buchteile zum Thema "Otogl"

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„Otog Dinosaur Fauna and Footprints“. In Dictionary of Geotourism, 452. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-2538-0_1799.

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Guan, Haoqin, Ying Su, Wenjia Guo, Chen Chen, Xiaodong Xie und Xiaoyi Lv. „A Prognostic Model of Genetic Markers for Triple-Negative Breast Cancer Based on Machine Learning and Bioinformatics Analysis“. In Studies in Health Technology and Informatics. IOS Press, 2023. http://dx.doi.org/10.3233/shti230854.

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Triple negative breast cancer (TNBC) that has low survival rate and prognosis due to its heterogeneity and lack of reliable molecular targets for effective targeted therapy. Therefore, finding new biomarkers is crucial for the targeted treatment of TNBC. The experimental data from the Cancer Genome Atlas database (TCGA).First, key genes associated with TNBC prognosis were screened and used for survival analysis using a single-factor COX regression analysis combined with three algorithms: LASSO, RF and SVM-RFE. Multi-factor COX regression analysis was then used to construct a TNBC risk prognostic model. Four key genes associated with TNBC prognosis were screened as TENM2, OTOG, LEPR and HLF. Among them, OTOG is a new biomarker. Survival analysis showed a significant effect of four key genes on OS in TNBC patients (P<0.05). The experiment showed that four key genes could provide new ideas for targeting therapy for TNBC patients and improved prognosis and survival.
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Geshi, Nobuo. „Development of dyke and sheet swarms controlled by magma supply rate – an example from the Miocene Otoge igneous complex, central Japan“. In Dyke Swarms - Time Markers of Crustal Evolution, 161–70. Taylor & Francis, 2006. http://dx.doi.org/10.1201/noe0415398992.ch11.

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Konferenzberichte zum Thema "Otogl"

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Nakatsuka, Tadashi, und Shigeo Okuma. „Aeromagnetic 3D subsurface imaging in the Otoge Cauldron, Shitara area, Central Japan“. In Proceedings of the 10th SEGJ International Symposium. Society of Exploration Geophysicists of Japan, 2011. http://dx.doi.org/10.1190/segj102011-001.70.

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Azuma, Makiko, Takuya Handa und Kazuteru Komine. „«Otogi Box»: a cubic haptic interface for presenting a story through tactile communication“. In 9th International Conference on Kansei Engineering and Emotion Research (KEER2022). Kansei Engineering and Emotion Research (KEER), 2022. http://dx.doi.org/10.5821/conference-9788419184849.55.

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Haptic technology provides users with an experience that is unattainable via audiovisual information alone. Researchers have previously attempted to synchronize tactile information with video to enhance the multimedia experience, although their studies were based on the assumption that visual information is present. Tactile stimuli usually act as additional information for a story and do not normally arouse people’s imagination regarding a story; a door opening, water dripping onto the floor, or someone walking across the floor is usually presented through visual information. This study proposes the “Otogi Box,” a cubic haptic storytelling interface using tactile stimuli. The haptic interface provides a whole new user experience, letting them feel the story unfold in their hands. The interface independently vibrates each of its faces based on the audio signals providing various touch sensations that fit a specific story. We present “Dwarf’s House” as a demo story, wherein users feel a dwarf realistically entering and exiting the box. For instance, the right face vibrates as if a door is opening when the dwarf opens the door on the right side of the house. The basic storytelling capabilities of the interface was tested through a user evaluation. The results revealed that the proposed interface could effectively present a simple story through tactile sense without any visual information, and enabled stimulation of users’ imagination in a unique manner.
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Wu, Jiabin, Lili Xu, Hexiang Zheng, Xuesong Cao und Haiyuan Lu. „Spatiotemporal Assessment of Evapotranspiration of Desert Steppe in Northern China: A Case of OTOG Front Banner“. In IGARSS 2021 - 2021 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2021. http://dx.doi.org/10.1109/igarss47720.2021.9554410.

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