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Zeitschriftenartikel zum Thema "Opnl"

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Martins, Jéssica Santa Cruz de Carvalho, Thiago das Chagas Sousa, Maria de Lourdes de Aguiar Oliveira, Etel Rodrigues Pereira Gimba, Marilda Mendonça Siqueira und Aline da Rocha Matos. „Total Osteopontin and Its Isoform OPN4 Are Differently Expressed in Respiratory Samples during Influenza A(H1N1)pdm09 Infection and Progression“. Microorganisms 11, Nr. 5 (20.05.2023): 1349. http://dx.doi.org/10.3390/microorganisms11051349.

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Influenza A virus (IAV) infection affects the human respiratory tract, causing an acute and highly contagious disease. Individuals with comorbidities and in the extremes of age are classified as risk groups for serious clinical outcomes. However, part of the severe infections and fatalities are observed among young healthy individuals. Noteworthy, influenza infections lack specific prognostic biomarkers that would predict the disease severity. Osteopontin (OPN) has been proposed as a biomarker in a few human malignancies and its differential modulation has been observed during viral infections. However, OPN expression levels in the primary site of IAV infection have not been previously investigated. Therefore, we evaluated the transcriptional expression patterns of total OPN (tOPN) and its splicing isoforms (OPNa, OPNb, OPNc, OPN4, and OPN5) in 176 respiratory secretion samples collected from human influenza A(H1N1)pdm09 cases and a group of 65 IAV-negative controls. IAV samples were differentially classified according to their disease severity. tOPN was more frequently detected in IAV samples (34.1%) when compared with the negative controls (18.5%) (p < 0.05), as well as in fatal (59.1%) versus non-fatal IAV samples (30.5%) (p < 0.01). OPN4 splice variant transcript was more prevalent in IAV cases (78.4%) than in the negative controls (66.1%) (p = 0.05) and in severe cases (85.7%) in relation to the non-severe ones (69.2%) (p < 0.01). OPN4 detection was also associated with severity symptoms such as dyspnea (p < 0.05), respiratory failure (p < 0.05), and oxygen saturation < 95% (p < 0.05). In addition, the OPN4 expression level was increased in the fatal cases of respiratory samples. Our data indicated that tOPN and OPN4 had a more pronounced expression pattern in IAV respiratory samples, pointing to the potential use of these molecules as biomarkers to evaluate disease outcomes.
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Ferreira, Luciana, Raquel Lima, Ana Bastos, Andreia Silva, Catarina Tavares, Ana Pestana, Elisabete Rios et al. „OPNa Overexpression Is Associated with Matrix Calcification in Thyroid Cancer Cell Lines“. International Journal of Molecular Sciences 19, Nr. 10 (30.09.2018): 2990. http://dx.doi.org/10.3390/ijms19102990.

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Osteopontin (OPN) spliced variants (OPN-SV: OPNa, OPNb, and OPNc) are aberrantly expressed in tumors and frequently associated with cancer progression. This holds true for papillary thyroid carcinoma (PTC), which is the most common type of thyroid cancer (TC). PTC often presents with desmoplasia and dystrophic calcification, including psammoma bodies (PB). This work aimed to investigate total OPN (tOPN) and OPN-SV expression and their association with the presence of PB in the PTC classical variants (cPTC), as well as the involvement of OPN-SV in matrix calcification of TC cell lines. We found that cPTC samples presenting PB showed higher OPN expression levels. In TC cell lines, OPNa overexpression promotes higher matrix calcification and collagen synthesis when compared to that of clones overexpressing OPNb or OPNc. In response to OPN knockdown, calcification was inhibited, paralleled with the downregulation of calcification markers. In conclusion, our data evidenced that OPN expression is associated with the presence of PB in cPTC samples. Among the OPN-SV, OPNa is the main contributor to matrix calcification in tested TC cells, providing clues to a better understanding on the biology and ethiopathogenesis of the calcification process in TC cells.
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Zhang, Ziyu, Liangliang Zheng, Wei Xu, Tan Gao, Xiaobin Wu und Biao Yang. „Blind Remote Sensing Image Deblurring Based on Overlapped Patches’ Non-Linear Prior“. Sensors 22, Nr. 20 (16.10.2022): 7858. http://dx.doi.org/10.3390/s22207858.

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The remote sensing imaging environment is complex, in which many factors cause image blur. Thus, without prior knowledge, the restoration model established to obtain clear images can only rely on the observed blurry images. We still build the prior with extreme pixels but no longer traverse all pixels, such as the extreme channels. The features are extracted in units of patches, which are segmented from an image and partially overlap with each other. In this paper, we design a new prior, i.e., overlapped patches’ non-linear (OPNL) prior, derived from the ratio of extreme pixels affected by blurring in patches. The analysis of more than 5000 remote sensing images confirms that OPNL prior prefers clear images rather than blurry images in the restoration process. The complexity of the optimization problem is increased due to the introduction of OPNL prior, which makes it impossible to solve it directly. A related solving algorithm is established based on the projected alternating minimization (PAM) algorithm combined with the half-quadratic splitting method, the fast iterative shrinkage-thresholding algorithm (FISTA), fast Fourier transform (FFT), etc. Numerous experiments prove that this algorithm has excellent stability and effectiveness and has obtained competitive processing results in restoring remote sensing images.
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Bastos, Ana Clara Ana Clara Santos da Fonseca, Luciana Bueno Ferreira, Mariana Emerenciano und Etel Rodrigues Pereira Gimba. „Abstract 6719: Osteopontin-c is worse prognostic marker and mediate key steps associated with central nervous system infiltration in B-cell acute lymphoblastic leukemia cells“. Cancer Research 83, Nr. 7_Supplement (04.04.2023): 6719. http://dx.doi.org/10.1158/1538-7445.am2023-6719.

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Abstract B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric malignance, but 35% of patients still relapse after chemotherapy treatment, mainly in the central nervous system (CNS). In order to search for new biomarkers that could predict CNS infiltration and relapse, many studies are trying to find gene products aberrantly expressed in these patients, including osteopontin (OPN). The OPN primary transcript undergoes alternative splicing, generating at least five OPN splicing isoforms (OPN-SI), named OPNa, OPNb, OPNc, OPN4 and OPN5, that have tumor specific roles and have been reported as biomarkers in solid tumors. However, knowledge regarding OPN-SI in B-ALL is scarce. This study aimed to investigate the expression patterns and roles of OPN-SI in CNS infiltration in B-ALL. OPN-SI transcript levels were analyzed by quantitative real time PCR (qRT-PCR) assays using RNA extracted from 54 B-ALL pediatric patient blood samples or from RS4,11 cell line. OPNc transcript knock-down in RS4;11 cells (a B-ALL cell line containing the MLL gene fusion) was performed using anti-OPNc or control scrambled antisense DNA oligomers (anti-OPNc-ASOs and Scbl-ASO, respectively). These oligomers were transfected in RS4;11 cells and the in vitro effects of OPNc knock-down were evaluated by several functional assays, such as cell viability by MTT analysis, cell adhesion, and transmigration and invasion assays using a boyden chamber device. Among tested OPN-SI, OPNc is the most highly expressed OPN-SI in B-ALL patient samples containing the MLL fusion gene, when compared to those samples harboring the ETV6-RUNX1 fusion gene (p&lt;0,005). High OPNc expression levels were significantly associated with poor prognostic features, such as high-risk classification (p&lt;0,005), CNS infiltration and high white blood cell counting (p&lt;0,05). The RS4;11 cells in which OPNc was knocked-down decreased their OPNc expression levels in 85% in relation to control Scbl-ASO transfected cells (p&lt;0,005). These cells decreased their viability in 41% (p&lt;0,05), besides displaying a 55% decrease in RS4;11 cell adhesion to matrigel. In addition, these cells decreased their capacity to transmigrate (54%) and invade the matrigel (51%) in comparison to control cells. In summary, these results suggest that OPNc transcript levels are associated with B-ALL worse prognostic features and that it may mediate some key steps involved on CNS infiltration mechanistic. Hence, our data provide important basis for the potential use of OPNc as a biomarker for B-ALL CNS relapse and for the involvement of this isoform on some steps that can mediate CNS invasion, opening new opportunities to improve B-ALL pediatric patients’ survival rates and quality of life. Citation Format: Ana Clara Ana Clara Santos da Fonseca Bastos, Luciana Bueno Ferreira, Mariana Emerenciano, Etel Rodrigues Pereira Gimba. Osteopontin-c is worse prognostic marker and mediate key steps associated with central nervous system infiltration in B-cell acute lymphoblastic leukemia cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 6719.
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Ferreira, Luciana Bueno, Catarina Eloy, Ana Pestana, Joana Lyra, Margarida Moura, Hugo Prazeres, Catarina Tavares, Manuel Sobrinho-Simões, Etel Gimba und Paula Soares. „Osteopontin expression is correlated with differentiation and good prognosis in medullary thyroid carcinoma“. European Journal of Endocrinology 174, Nr. 4 (April 2016): 551–61. http://dx.doi.org/10.1530/eje-15-0577.

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BackgroundOsteopontin (OPN) or secreted phosphoprotein 1 (SPP1) is a matricellular glycoprotein whose expression is elevated in various types of cancer and has been shown to be involved in tumourigenesis and metastasis in many malignancies, including follicular cell-derived thyroid carcinomas. Its role in C-cell-derived thyroid lesions and tumours remains to be established.ObjectiveThe objective of this study is to clarify the role of OPN expression in the development of medullary thyroid carcinoma (MTC).MethodsOPN expression was analysed in a series of 116 MTCs by immunohistochemistry and by qPCR mRNA quantification of the 3 OPN isoforms (OPNa, OPNb and OPNc) in six cases from which fresh frozen tissue was available. Statistical tests were used to evaluate the relationship of OPN expression and the clinicopathological and molecular characteristics of patients and tumours.ResultsOPN expression was detected in 91 of 116 (78.4%) of the MTC. We also observed high OPN expression in C-cell hyperplasia as well as in C-cells scattered in the thyroid parenchyma adjacent to the tumours. OPN expression was significantly associated with smaller tumour size, PTEN nuclear expression and RAS status, and suggestively associated with non-invasive tumours. OPNa isoform was expressed significantly at higher levels in tumours than in non-tumour samples. OPNb and OPNc presented similar levels of expression in all samples. Furthermore, OPNa isoform overexpression was significantly associated with reduced growth and viability in the MTC-derived cell line (TT).ConclusionThe expression of OPN in normal C-cells and C-cell hyperplasia suggests that OPN is a differentiation marker of C-cells, rather than a marker of biological aggressiveness in this setting. At variance with other cancers, OPN expression is associated with good prognostic features in MTC.
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Ho, Nguyen-Tuong, Shu-Wei Lin, Yi-Rong Lee, Chii-Ruey Tzeng und Shu-Huei Kao. „Osteopontin Splicing Isoforms Contribute to Endometriotic Proliferation, Migration, and Epithelial-Mesenchymal Transition in Endometrial Epithelial Cells“. International Journal of Molecular Sciences 23, Nr. 23 (05.12.2022): 15328. http://dx.doi.org/10.3390/ijms232315328.

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Osteopontin (OPN) isoforms, including OPNb and OPNc, promote malignancy and may contribute to the pathogenesis of endometriosis, a benign disorder with multiple characteristics resembling malignant tumors. In our experiments, OPNb and OPNc were significantly overexpressed in both endometriosis and adenomyosis compared to the normal endometrium. Upregulation of CD44v and the epithelial–mesenchymal transition (EMT) process was also present in endometriotic lesions. Overexpression of OPNb and OPNc splicing variants in endometriotic cells evoked morphological changes, actin remodeling, cell proliferation, cell migration, and EMT through binding OPN ligand receptors CD44 and αvβ3, subsequently activating the PI3K and NF-ĸB pathways. We elucidated the causal role of OPN splice variants in regulating endometriotic cell growth, which may promote the development of OPN-targeted therapies for patients suffering from endometriotic disorders.
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Buhr, Ethan D., Wendy W. S. Yue, Xiaozhi Ren, Zheng Jiang, Hsi-Wen Rock Liao, Xue Mei, Shruti Vemaraju et al. „Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea“. Proceedings of the National Academy of Sciences 112, Nr. 42 (21.09.2015): 13093–98. http://dx.doi.org/10.1073/pnas.1516259112.

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The molecular circadian clocks in the mammalian retina are locally synchronized by environmental light cycles independent of the suprachiasmatic nuclei (SCN) in the brain. Unexpectedly, this entrainment does not require rods, cones, or melanopsin (OPN4), possibly suggesting the involvement of another retinal photopigment. Here, we show that the ex vivo mouse retinal rhythm is most sensitive to short-wavelength light but that this photoentrainment requires neither the short-wavelength–sensitive cone pigment [S-pigment or cone opsin (OPN1SW)] nor encephalopsin (OPN3). However, retinas lacking neuropsin (OPN5) fail to photoentrain, even though other visual functions appear largely normal. Initial evidence suggests that OPN5 is expressed in select retinal ganglion cells. Remarkably, the mouse corneal circadian rhythm is also photoentrainable ex vivo, and this photoentrainment likewise requires OPN5. Our findings reveal a light-sensing function for mammalian OPN5, until now an orphan opsin.
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Upton, Brian A., Nicolás M. Díaz, Shannon A. Gordon, Russell N. Van Gelder, Ethan D. Buhr und Richard A. Lang. „Evolutionary Constraint on Visual and Nonvisual Mammalian Opsins“. Journal of Biological Rhythms 36, Nr. 2 (25.03.2021): 109–26. http://dx.doi.org/10.1177/0748730421999870.

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Animals have evolved light-sensitive G protein–coupled receptors, known as opsins, to detect coherent and ambient light for visual and nonvisual functions. These opsins have evolved to satisfy the particular lighting niches of the organisms that express them. While many unique patterns of evolution have been identified in mammals for rod and cone opsins, far less is known about the atypical mammalian opsins. Using genomic data from over 400 mammalian species from 22 orders, unique patterns of evolution for each mammalian opsins were identified, including photoisomerases, RGR-opsin (RGR) and peropsin (RRH), as well as atypical opsins, encephalopsin (OPN3), melanopsin (OPN4), and neuropsin (OPN5). The results demonstrate that OPN5 and rhodopsin show extreme conservation across all mammalian lineages. The cone opsins, SWS1 and LWS, and the nonvisual opsins, OPN3 and RRH, demonstrate a moderate degree of sequence conservation relative to other opsins, with some instances of lineage-specific gene loss. Finally, the photoisomerase, RGR, and the best-studied atypical opsin, OPN4, have high sequence diversity within mammals. These conservation patterns are maintained in human populations. Importantly, all mammalian opsins retain key amino acid residues important for conjugation to retinal-based chromophores, permitting light sensitivity. These patterns of evolution are discussed along with known functions of each atypical opsin, such as in circadian or metabolic physiology, to provide insight into the observed patterns of evolutionary constraint.
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Karthikeyan, Ramanujam, Wayne I. L. Davies und Lena Gunhaga. „Non-image-forming functional roles of OPN3, OPN4 and OPN5 photopigments“. Journal of Photochemistry and Photobiology 15 (Juni 2023): 100177. http://dx.doi.org/10.1016/j.jpap.2023.100177.

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Guido, Mario. „Illuminating the Inner Retina of Vertebrates: Multiple Opsins and Non-Visual Photoreceptors“. Science Reviews - from the end of the world 2, Nr. 1 (18.12.2020): 7–17. http://dx.doi.org/10.52712/sciencereviews.v2i1.35.

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Throughout evolution, the need to detect light has generated highly specialized photoreceptor cells that in vertebrates are mainly located in the retina. The most studied photodetectors within these cells are the visual photoreceptors “cones and rods” responsible for day and night vision, respectively. These cells contain photosensitive molecules consisting of a protein part called “opsin” that binds a chromophore derived from vitamin A, retinaldehyde, capable of photoisomerizing from 11-cis retinal to all-trans retinal form, and triggering the light responses that lead to vision. However, other cells of the inner retina of vertebrates [retinal ganglion cells (RGCs), horizontal cells (HCs), and Muller’s glial cells] are currently known to express non-visual photopigments such as melanopsin (Opn4), encephalopsin (Opn3) and neuropsin (Opn5), which would be involved in diverse functions not associated with imaging. Melanopsin is the most widely studied of them, it is expressed in intrinsically photosensitive RGCs (ipRGCs) and HCs of the chicken retina and participates in setting the biological clock, the pupillary light reflex, and presumably in other reflex and subconscious functions, in addition to the lateral interaction between visual photoreceptors and HCs. It is noteworthy that these non-visual photopigments (Opn3, Opn4 and Opn5) respond to blue and/or near violet region light. This particular photosensitivity may provide individuals with a broader spectrum of response to light stimulation within the visible beyond the scope of the visual photoreceptors, regulating an important number of functions not yet completely identified. We can conclude that “a constellation of cells and photoreceptor molecules are present in the inner retina of vertebrates, and from very early stages of development, even before any sign of vision may occur.”
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Dissertationen zum Thema "Opnl"

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Pipiraitė, Marija. „Opalo-geležies porfirino hibridinių darinių optinių savybių tyrimas“. Master's thesis, Lithuanian Academic Libraries Network (LABT), 2008. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2008~D_20080924_184857-77651.

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Magistriniame darbe yra nagrinėjami švaraus opalo pralaidumo spektrai. Nustatyta, kad stop juostos padėtis priklauso nuo spindulio kritimo kampo į bandinį. Apskaičiuoti pagrindiniai parametrai: tarp-plokštuminis atstumas d, opalo sferų diametras D, bandinio lūžio rodiklis n ir opalo sferų lūžio rodiklis . Pagamintas opal-FeTTPS hibridinis darinys ir išnagrinėtas jo pralaidumas bei magnetinis cirkulinis dichroizmas. Nustatyta, kad FeTTPS stop juostos padėtis prie įvairių kampų šiek tiek skiriasi nuo švaraus opalo. Hibridinio darinio magnetinis cirkulinis dichroizmas kinta keičiant kritimo kampą ar stop juostos padėtį.
In this work transmission optics of opal photonic crystals and infiltrated with iron porphyrin was studied. Work analyses synthetic opal crystals grown by means of sedimentation from the spheres of SiO2. Samples were 0.9 mm thick, and their surfaces planes were parallel (111) to crystallographic planes. In these samples, the stop band due to Bragg reflection from the (111) plane was observed in the spectral region of 0.45-0.7 µm at angles of light incidence. Iron porphyries FeTTPS magnetic circular dichroism was also investigated. Synthetic opal crystals composed of silica spheres were infiltrated with (c=10 mM, pH=6.8) buffered phosphate solution of iron porphyrin. In optical studies the FeTPPS-impregnated opal samples were immersed in hexane solution to vary average refractive index of composite system and to control the mutual positions of the opal stop band and absorption bands of FeTPPS. FeTPPS magnetic circular dichroism spectra dependency on opal stop band position was noted. The experimental opal transmission spectra date were analyzed in which the optical response of the opal and infiltrated with iron porphyrin was calculated by using a Bragg’s law and it was found that spacing between adjacent [111] lattice planes d is 254.95 nm, opal crystal composed of silica spheres of diameter is 312 nm and average refractive index of composite system – 1.35.
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Roney, J. Michael (John Michael) 1958 OPAL Carleton University Dissertation Physics. „The OPAL vertex detector“. Ottawa.:, 1989.

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Maysami, Mohammad. „Lithology constraints from seismic waveforms : application to opal-A to opal-CT transition“. Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/540.

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In this work, we present a new method for seismic waveform characterization, which is aimed at extracting detailed litho-stratigraphical information from seismic data. We attempt to estimate the lithological attributes from seismic data according to our parametric representation of stratigraphical horizons, where the parameter values provide us with a direct link to nature of lithological transitions. We test our method on a seismic dataset with a strong diagenetic transition (opal-A to opal-CT transition). Given some information from cutting samples of well, we use a percolation-based model to construct the elastic profile of lithological transitions. Our goal is to match parametric representation for the diagenetic transition in both real data and synthetic data given by these elastic profiles. This match may be interpreted as a well-seismic tie, which reveals lithological information about stratigraphical horizons.
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Opel, Andreas. „Laboranalytische Überprüfung der Rezepturtreue bei der Asphaltherstellung im praktischen Mischanlagenbetrieb“. [S.l.] : [s.n.], 2006. http://137.193.200.177/ediss/opel-andreas/meta.html.

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Maka, Thorsten. „Thin film opal photonic crystals“. [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=974086991.

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Khokar, Ali Zarrar. „Opal based 3D photonic crystals“. Thesis, University of Glasgow, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.438610.

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Wetterling, Dirk. „Bestimmung des Fragmentationsverhaltens multihadronischer Z0-Zerfälle an Hand von S-Antihyperon-Korrelationsstudien [Sigma-Antihyperon-Korrelationsstudien]“. [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=964904578.

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Lebrun, Delphine. „Fabrication of inverse opal oxide structures for efficient light harvesting“. Licentiate thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-232228.

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Artificial opals are self-assembled face centered cubic (fcc) structures of  spherically shaped beads, which interesting applications as photonic band gap materials. Inverse opals are photonic crystals consisting of fcc paced voids of a low refractive index material imbedded in a high refractive index material. Such structures has been used to enhance the photocatalytic effect of different materials and motivates further studies to improve the deposition process of the opal templates and their inversion. We state the fabrication method to design and model metal oxide inverse opals. We have successfully created alumina and alumina-titania inverse opals. With the help of simulations, we engineered inverse opals with self-assembly and atomic layer deposition.
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Graham, Matthew. „DEVELOPMENT OF HIGH REFRACTIVE INDEX POLY(THIOPHENE) FOR THE FABRICATION OF ALL ORGANIC 3-D PHOTONIC MATERIALS WITH A COMPLETE PHOTONIC BAND GAP“. University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1164049666.

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Knee, Simon. „Opal : modular programming using the BSP model“. Thesis, University of Oxford, 1997. http://ora.ox.ac.uk/objects/uuid:97d95f01-a098-499c-8c07-303b853c2460.

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Parallel processing can provide the huge computational resources that are required to solve todays grand challenges, at a fraction of the cost of developing sequential machines of equal power. However, even with such attractive benefits the parallel software industry is still very small compared to its sequential counterpart. This has been attributed to the lack of an accepted parallel model of computation, therefore leading to software which is architecture dependent with unpredictable performance. The Bulk Synchronous Parallel (BSP) model provides a solution to these problems and can be compared to the Von Neumann model of sequential computation. In this thesis we investigate the issues involved in providing a modular programming environment based on the BSP model. Using our results we present Opal, a BSP programming language that has been designed for parallel programming-in-the-large. While other BSP languages and libraries have been developed, none of them provide support for libraries of parallel algorithms. A library mechanism must be introduced into BSP without destroying the existing cost model. We examine such issues and show that the active library mechanism of Opal leads to algorithms which still have predictable performance. If algorithms are to retain acceptable levels of performance across a range of machines then they must be able to adapt to the architecture that they are executing on. Such adaptive algorithms require support from the programming language, an issue that has been addressed in Opal. To demonstrate the Opal language and its modular features we present a number of example algorithms. Using an Opal compiler that has been developed we show that we can accurately predict the performance of these algorithms. The thesis concludes that by using Opal it is possible to program the BSP model in a modular fashion that follows good software engineering principles. This enables large scale parallel software to be developed that is architecture independent, has predictable performance and is adaptive to the target architecture.
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Bücher zum Thema "Opnl"

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Okawa, Atsushi, Morio Matsumoto, Motoki Iwasaki und Yoshiharu Kawaguchi, Hrsg. OPLL. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1.

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Yonenobu, Kazuo, Takashi Sakou und Keiro Ono, Hrsg. OPLL. Tokyo: Springer Japan, 1997. http://dx.doi.org/10.1007/978-4-431-67046-9.

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Yonenobu, Kazuo, Kozo Nakamura und Yoshiaki Toyama, Hrsg. OPLL. Tokyo: Springer Japan, 2006. http://dx.doi.org/10.1007/978-4-431-32563-5.

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Snelling, Lauraine. Opal. Waterville, Me: Thorndike Press, 2005.

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Rhodes, Elvi. Opal. Leicester: Ulverscroft, 1985.

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Desai, Kendra Leah. Opal. Santa Monica, California: Kendra Leah Desai, 2014.

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Snelling, Lauraine. Opal. Minneapolis, Minn: Bethany House Publishers, 2005.

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Bennetts, Pamela. Opal. London: Hale, 1986.

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Bennetts, Pamela. Opal. London: Magna, 1987.

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Ashfield, Helen. Opal. New York: St. Martin's Press, 1986.

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Buchteile zum Thema "Opnl"

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Chiari, Michele, Dino Mandrioli und Matteo Pradella. „Model-Checking Structured Context-Free Languages“. In Computer Aided Verification, 387–410. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-81688-9_18.

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AbstractThe problem of model checking procedural programs has fostered much research towards the definition of temporal logics for reasoning on context-free structures. The most notable of such results are temporal logics on Nested Words, such as CaRet and NWTL. Recently, the logic OPTL was introduced, based on the class of Operator Precedence Languages (OPL), more powerful than Nested Words. We define the new OPL-based logic POTL, and provide a model checking procedure for it. POTL improves on NWTL by enabling the formulation of requirements involving pre/post-conditions, stack inspection, and others in the presence of exception-like constructs. It improves on OPTL by being FO-complete, and by expressing more easily stack inspection and function-local properties. We developed a model checking tool for POTL, which we experimentally evaluate on some interesting use-cases.
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Okawa, Atsushi. „History of Research“. In OPLL, 3–6. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_1.

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Toguchida, Junya. „Application of iPS Cell Technology for OPLL“. In OPLL, 65–73. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_10.

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Miyamoto, Takeshi. „Mechanisms Underlying OPLL Development in Tiptoe Walking (ttw) Mice“. In OPLL, 75–79. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_11.

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Konomi, Tsunehiko, Morito Takano, Yuji Komaki, Keigo Hikishima, Kanehiro Fujiyoshi, Osahiko Tsuji, Hideyuki Okano, Morio Matsumoto und Masaya Nakamura. „In Vivo Tracing of Neural Tracts in Tip-Toe Walking Yoshimura Mice by Diffusion Tensor Tractography“. In OPLL, 81–88. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_12.

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Tsuji, Takashi, und Morio Matsumoto. „Metabolomics Analysis of OPLL Patients“. In OPLL, 89–97. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_13.

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Yamazaki, Masashi, Tetsuya Abe, Toru Funayama, Hiroshi Takahashi, Satoshi Maki, Takeo Furuya und Masao Koda. „Diagnosis of OPLL and OLF: Overview“. In OPLL, 101–12. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_14.

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Ozawa, Hiroshi. „Clinical Manifestation of Cervical OPLL“. In OPLL, 113–18. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_15.

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Katsumi, Keiichi, Toru Hirano, Kei Watanabe, Tomohiro Izumi, Masayuki Ohashi, Tatsuki Mizouchi und Naoto Endo. „Three-Dimensional Imaging of Cervical Ossification of the Posterior Longitudinal Ligament“. In OPLL, 119–28. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_16.

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Matsuyama, Yukihiro, Go Yoshida und Tomohiro Banno. „Clinical Manifestations of Thoracic Ossification of the Posterior Longitudinal Ligament (OPLL) and Ossification of the Ligament Flavum (OLF)“. In OPLL, 129–34. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-3855-1_17.

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Konferenzberichte zum Thema "Opnl"

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Moran, Steven E., Robert L. Law, Peter N. Craig und Warren M. Goldberg. „Optically phase-locked electronic speckle pattern interferometer“. In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/oam.1986.fu3.

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The design, operation, and characteristics of an optically phase-locked electronic speckle pattern interferometer (OPL-ESPI) are described. The OPL-ESPI sensor generates real-time equal Doppler speckle contours of vibrating objects from unstable sensor platforms with a Doppler resolution of 30 Hz and a maximum tracking range of ±5 MHz. Laboratory measurements of the sensor’s characteristics indicate a velocity tracking range of at least 8 μm/s to 8 cm/s, or a dynamic range of 40 dB. The optical phase-locked loop (OPLL) not only compensates for the deleterious effects of ambient background vibration, but also provides the basis for a new ESPI video signal processing technique which produces high contrast speckle contours. The ability to locate the OPLL lock point anywhere within the field of view of the sensor also allows examination of the spatial detail of low contrast speckle contours whose low visibility would otherwise make interpretation difficult. Since the OPL-ESPI system has local oscillator phase modulation capability, it offers the potential for detection of vibrations with amplitudes of less than a hundredth of a wavelength.
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Furche, Tim, Georg Gottlob, Giovanni Grasso, Xiaonan Guo, Giorgio Orsi und Christian Schallhart. „OPAL“. In the 21st international conference. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2187836.2187948.

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Guo, Xiaonan, Jochen Kranzdorf, Tim Furche, Giovanni Grasso, Giorgio Orsi und Christian Schallhart. „OPAL“. In the 21st international conference companion. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2187980.2188047.

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Aranguren, Mikel Egaña, Jesualdo Tomás Fernández-Breis und Erick Antezana. „OPPL-Galaxy“. In the 4th International Workshop. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2166896.2166903.

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Scaffidi, Christopher, Kevin Bierhoff, Eric Chang, Mikhael Felker, Herman Ng und Chun Jin. „Red Opal“. In the 8th ACM conference. New York, New York, USA: ACM Press, 2007. http://dx.doi.org/10.1145/1250910.1250938.

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Papavero, Luca. „Cervical Myelopathy: OPLL“. In eccElearning Postgraduate Diploma in Spine Surgery. eccElearning, 2017. http://dx.doi.org/10.28962/01.3.039.

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Grudinkin, S. A., S. F. Kaplan, N. F. Kartenko, D. A. Kurdyukov und V. G. Golubev. „Photonic crystal properties of opal-hematite and opal-magnetite films“. In Photonics, Devices, and Systems IV, herausgegeben von Pavel Tománek, Dagmar Senderáková und Miroslav Hrabovský. SPIE, 2008. http://dx.doi.org/10.1117/12.818010.

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Megaw, Peter K. M. „Electric Opal: Green daylight-luminescing hyalite opal from Zacatecas, Mexico“. In 39th Annual New Mexico Mineral Symposium. Socorro, NM: New Mexico Bureau of Geology and Mineral Resources, 2018. http://dx.doi.org/10.58799/nmms-2018.580.

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Law, Mark, Alessandra Russo, Krysia Broda und Elisa Bertino. „Scalable Non-observational Predicate Learning in ASP“. In Thirtieth International Joint Conference on Artificial Intelligence {IJCAI-21}. California: International Joint Conferences on Artificial Intelligence Organization, 2021. http://dx.doi.org/10.24963/ijcai.2021/267.

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Recently, novel ILP systems under the answer set semantics have been proposed, some of which are robust to noise and scalable over large hypothesis spaces. One such system is FastLAS, which is significantly faster than other state-of-the-art ASP-based ILP systems. FastLAS is, however, only capable of Observational Predicate Learning (OPL), where the learned hypothesis defines predicates that are directly observed in the examples. It cannot learn knowledge that is indirectly observable, such as learning causes of observed events. This class of problems, known as non-OPL, is known to be difficult to handle in the context of non-monotonic semantics. Solving non-OPL learning tasks whilst preserving scalability is a challenging open problem. We address this problem with a new abductive method for translating examples of a non-OPL task to a set of examples, called possibilities, such that the original example is covered iff at least one of the possibilities is covered. This new method allows an ILP system capable of performing OPL tasks to be "upgraded" to solve non-OPL tasks. In particular, we present our new FastNonOPL system, which upgrades FastLAS with the new possibility generation. We compare it to other state-of-the-art ASP-based ILP systems capable of solving non-OPL tasks, showing that FastNonOPL is significantly faster, and in many cases more accurate, than these other systems.
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Smith, D. W. „Novel techniques for heterodyne and homodyne detection“. In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/oam.1986.fe3.

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For future high capacity coherent optical fiber systems homodyne detection should offer advantages in terms of both receiver sensitivity and receiver bandwidth over heterodyne detection. However, conventional homodyne detection requires an optoelectronic phase-locked loop (OPLL) containing a laser with exceptionally low phase noise. Homodyne detection has been the subject of several recent theoretical papers but as yet there is only one report of an experimental semiconductor laser homodyne OPLL. This early practical work has highlighted many of the difficult problems still to be tackled.
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Berichte der Organisationen zum Thema "Opnl"

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Bazer, Fuller W., Arieh Gertler und Elisha Gootwine. Role of Placental Lactogen in Sheep. United States Department of Agriculture, Januar 2001. http://dx.doi.org/10.32747/2001.7574339.bard.

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Central problems in sheep and dairy cattle production are reproductive failure due to embryonic/fetal mortality and low birth weights, especially in prolific breeds, and reduced milk yields which adversely affect neonatal survival and economy of production. The sheep placenta expresses lactogenic (ovine placental lactogen, oPL) and somatogenic (ovine placental growth hormone, oGH) hormones. Our research has focused on the biological roles of oPL and oGH in function of the uterine endometrium during gestation and the mammary gland during pregnancy and lactation. Major conclusions were that: ( 1 ) immunization of prepubertal ewes against oPL resulted in increased birth weights of their lambs and their milk production during lactation; (2) neither oPL nor oGH had an antiluteolytic effect on uterine endometrium to affect lifespan of the corpus luteum; (3) only sequential exposure of the progesterone stimulated uterus to oIFNt and oPL or oGH increased endometrial gland proliferation and secretory protein gene expression; (4) oPL signals through a homodimer of ovine prolactin receptor (PRL-R) and heterodimer of oPRL-R and growth hormone receptor (GH-R); (5) exogenous recombinant oPL and oGH stimulated mammogenesis and milk yield during lactation; and (6) mutation of oPL and oGH was used to define specific biological effects and a rational basis for design of a specific receptor agonists or antagonists. This project was very productive in elucidating basic biological effects of oPL and oGH on intracellular signal transduction pathways, uterine development and secretory function, as well as mammogenesis and lactogenesis. We determined that immunization of prepubertal ewes against roPL increased birth weights of their lambs, especially those born as twins and triplets, as well as enhanced lactational performance. These studies significantly extended our knowledge of uterine and fetal-placental physiology and provided a foundation for new strategies to enhance reproductive and lactation efficiency. Based on these results, the major achievements were: 1) creation of a practical and cost effective management tool for producers to increase reproductive performance, neonatal survival, and milk yield of ewes in commercial flocks; and 2) define, for the first time, biological effects of oPL on endometrial functions and gene expression by uterine gland epithelium.
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Armas, Elvira, und Magaly Lavadenz. The Observation Protocol for Academic Literacies (OPAL); A Tool for Supporting Teachers of English Language Learners. CEEL, 2011. http://dx.doi.org/10.15365/ceel.article.2011.1.

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Schools and school systems are experiencing an instructional support gap that results in limited opportunities for educators to analyze, reflect on and improve research-based practices for ELLs so that outcomes for culturally and linguistically diverse students can change. To address this need, an inter-disciplinary research team from the Center for Equity for English Learners, comprised of educational leaders, teachers, researchers, and content experts developed a classroom observational instrument—the Observation Protocol for Academic Literacies (OPAL). The OPAL is intended for teachers, educational leaders, coaches, and others to conduct focused classroom observations for three potential purposes: research/evaluation, professional development, and coaching. In this article the authors introduce the OPAL’s research base, describe how to use the OPAL tool, and provide examples of the applied use of the OPAL to support professional learning and evaluate a three-year school reform effort.
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Yafimava, Katja. The OPAL Exemption Decision. Oxford Institute for Energy Studies, September 2017. http://dx.doi.org/10.26889/ei201709.

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Yafimava, Katja. The OPAL Exemption Decision. Oxford Institute for Energy Studies, Januar 2017. http://dx.doi.org/10.26889/9781784670771.

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Gaul, Roy D., Richard F. Pittenger und Larry D. Flick. CHURCH OPAL Research and Promulgation. Fort Belvoir, VA: Defense Technical Information Center, August 2005. http://dx.doi.org/10.21236/ada437233.

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Pang, Xiaoying. Hard edge dipole for OPAL. Office of Scientific and Technical Information (OSTI), August 2014. http://dx.doi.org/10.2172/1159043.

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Hill, C. A., C. M. Schluter und R. S. Harmon. Calcite/opal deposits at Yucca Mountain, Nevada: Pedogenic or hypogene? Office of Scientific and Technical Information (OSTI), Januar 1994. http://dx.doi.org/10.2172/227034.

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Kommareddy, Vamsee, Clayton Hughes, Simon David Hammond und Amro Awad. Opal: A Centralized Memory Manager for Investigating Disaggregated Memory Systems. Office of Scientific and Technical Information (OSTI), August 2018. http://dx.doi.org/10.2172/1467164.

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Cui, Jin. Study on OPAL-RT Simulation System Hardware in Loop and Simulation on Microgrid Black Start. Ames (Iowa): Iowa State University, Januar 2018. http://dx.doi.org/10.31274/cc-20240624-1349.

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J. PACES, L. NEYMARK, H. PERSING und J. WOODEN. DEMONSTRATING SLOW GROWTH RATES IN OPAL FROM Y.M.,NV, USING MICRODIGESTION AND ION-PROBE URANIUM-SERIES DATING. Office of Scientific and Technical Information (OSTI), Juli 2000. http://dx.doi.org/10.2172/840696.

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