Zeitschriftenartikel: „Open DSS“

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Abrahamian, Atossa Araxia. „Willing to Relocate: An Economist’s Case for Open Borders“. Dissent 64, Nr. 1 (2017): 81–88. http://dx.doi.org/10.1353/dss.2017.0016.

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Sierakowski, Sławomir. „Open Letter to the Parties: Time for the Neo-Dissidents“. Dissent 60, Nr. 2 (2013): 5–9. http://dx.doi.org/10.1353/dss.2013.0034.

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Atanaskova Mesinkovska, Natasha, Ruzica Z. Conic, Elizabeth A. Kiracofe und Allison T. Vidimos. „Treatment of Invasive Squamous Cell Carcinomas in an Open Clagett Window“. Dermatologic Surgery 41, Nr. 1 (Januar 2015): 170–72. http://dx.doi.org/10.1097/dss.0000000000000236.

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4

Gregg, Dawn G., und Michael Goul. „A proposal for an open DSS protocol“. Communications of the ACM 42, Nr. 11 (November 1999): 91–96. http://dx.doi.org/10.1145/319382.319400.

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5

Rivero, Raúl. „Search Order, and: Manifesto for the General Customs Office of the Republic, and: Open Gift“. Dissent 53, Nr. 2 (2006): 34–35. http://dx.doi.org/10.1353/dss.2006.0016.

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Hausauer, Amelia K. „Commentary on A Large, Open-Label, Phase 3 Safety Study of DaxibotulinumtoxinA for Injection in Glabellar Lines“. Dermatologic Surgery 47, Nr. 1 (11.08.2020): 47. http://dx.doi.org/10.1097/dss.0000000000002563.

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Mutalik, Sharad, Swapnil Shah, Varsha Sidwadkar und Meenaz Khoja. „Efficacy of Cyclosporine After Autologous Noncultured Melanocyte Transplantation in Localized Stable Vitiligo—A Pilot, Open Label, Comparative Study“. Dermatologic Surgery 43, Nr. 11 (November 2017): 1339–47. http://dx.doi.org/10.1097/dss.0000000000001190.

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8

Niforos, Francois, Raj Acquilla, Patricia Ogilvie, Marva Safa, Massimo Signorini, Lela Creutz, Graeme Kerson und Michael Silberberg. „A Prospective, Open-Label Study of Hyaluronic Acid-Based Filler With Lidocaine (VYC-15L) Treatment for the Correction of Infraorbital Skin Depressions“. Dermatologic Surgery 43, Nr. 10 (Oktober 2017): 1271–80. http://dx.doi.org/10.1097/dss.0000000000001127.

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Fabi, Sabrina G., Joel L. Cohen, Lawrence J. Green, Sunil Dhawan, Theda C. Kontis, Leslie Baumann, Todd M. Gross, Conor J. Gallagher, Jessica Brown und Roman G. Rubio. „DaxibotulinumtoxinA for Injection for the Treatment of Glabellar Lines: Efficacy Results From SAKURA 3, a Large, Open-Label, Phase 3 Safety Study“. Dermatologic Surgery 47, Nr. 1 (06.08.2020): 48–54. http://dx.doi.org/10.1097/dss.0000000000002531.

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Sattler, Gerhard, Wolfgang G. Philipp-Dormston, Helga Van Den Elzen, Cornelius Van Der Walt, Myooran Nathan, Julia Kolodziejczyk, Graeme Kerson und Benjeev Dhillon. „A Prospective, Open-Label, Observational, Postmarket Study Evaluating VYC-17.5L for the Correction of Moderate to Severe Nasolabial Folds Over 12 Months“. Dermatologic Surgery 43, Nr. 2 (Februar 2017): 238–45. http://dx.doi.org/10.1097/dss.0000000000000939.

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Green, Jeremy B., Kavita Mariwalla, Kyle Coleman, Glynis Ablon, Susan H. Weinkle, Conor J. Gallagher, Domenico Vitarella und Roman G. Rubio. „A Large, Open-Label, Phase 3 Safety Study of DaxibotulinumtoxinA for Injection in Glabellar Lines: A Focus on Safety From the SAKURA 3 Study“. Dermatologic Surgery 47, Nr. 1 (29.07.2020): 42–46. http://dx.doi.org/10.1097/dss.0000000000002463.

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Kronberger, M., P. Teutsch, B. Alessi, M. Steine, L. Ferrero, K. Graczewski, M. Juchert et al. „New galactic open cluster candidates from DSS and 2MASS imagery“. Astronomy & Astrophysics 447, Nr. 3 (10.02.2006): 921–28. http://dx.doi.org/10.1051/0004-6361:20054057.

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Marano, Langella, Basile, Cona, Michele, Manna, Teobaldelli, Saracino und Terribile. „A Geospatial Decision Support System Tool for Supporting Integrated Forest Knowledge at the Landscape Scale“. Forests 10, Nr. 8 (14.08.2019): 690. http://dx.doi.org/10.3390/f10080690.

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Forests are part of a complex landscape mosaic and play a crucial role for people living both in rural and urbanized spaces. Recent progresses in modelling and Decision Support System (DSS) applied to the forestry sector promise to improve public participative forest management and decision-making in planning and conservation issues. However, most DSS are not open-source systems, being in many cases software designed for site-specific applications in forest ecosystems. Furthermore, some of these systems often miss challenging the integration of other land uses within the landscape matrix, which is a key issue in modern forestry planning aiming at linking recent developments in open-source Spatial-DSS systems to sectorial forest knowledge. This paper aims at demonstrating that a new type of S-DSS, developed within the Life+ project SOILCONSWEB over an open-source Geospatial Cyber-Infrastructure (GCI) platform, can provide a strategic web-based operational tool for forest resources management and multi-purpose planning. In order to perform simulation modelling, all accessible via the Web, the GCI platform supports acquisition and processing of both static and dynamic data (e.g., spatial distribution of soil and forest types, growing stock and yield), data visualization and computer on-the-fly applications. The DSS forestry tool has been applied to a forest area of 5,574 ha in the southern Apennines of Peninsular Italy, and it has been designed to address forest knowledge and management providing operational support to private forest owners and decision-makers involved in management of forest landscape at different levels. Such a geospatial S-DSS tool for supporting integrated forest knowledge at landscape represents a promising tool to implement sustainable forest management and planning. Results and output of the platform will be shown through a short selection of practical case studies.

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Smith, Angela, Jeffrey W. Nix, Matthew Edward Nielsen, Eric Wallen und Raj Pruthi. „Prospective randomized controlled trial of robotic versus open radical cystectomy for bladder cancer: Median 3-year follow-up.“ Journal of Clinical Oncology 30, Nr. 5_suppl (10.02.2012): 284. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.284.

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284 Background: We reported our results on a prospective, randomized trial of open vs. robotic cystectomy in 2008. Three years later, we report our findings with regard to overall (OS) and disease-specific survival (DS), recurrence rates and long-term complications. Methods: A prospective, randomized study comparing open vs. robotic cystectomy for bladder cancer was initiated at our institution with IRB approval in 2008. A target accrual of 40 patients was established to evaluate for non-inferiority based upon nodal yield. Peri-operative and pathologic results were reported in 2008. We now report our median 36-month follow-up for this patient cohort. Results: Of the 41 patients, 21 were randomized to robotic and 20 to open. On surgical pathology, in the robotic group 14 patients had <= pT2, 3 pT3/T4, and 4 N+ disease. In the open group, 9 had <= pT2, 5 pT3/T4, and 7 N+ disease. No positive margins were noted. With median follow-up of 35 and 36 months in the robotic and open arms, OS was 65% (13/20) and 81% (17/21) respectively (p=0.3058). DSS was 68% in the open group (13/19) and 85% in the robotic group (17/20) (p=0.2733). There were 7 recurrences (35%) in the open cohort compared to 3 patients (14%) undergoing the robotic procedure (p=0.1589). Examining overall complications, there were no differences between the open and robotic groups when evaluating 30-day complications and >=90 day complications (p=0.8651). The open and robotic cohorts demonstrated 2 strictures in each cohort. Two parastomal hernias were noted in the open group compared to none in the robotic group. On multivariate analysis, controlling for age, BMI and pathologic stage, cystectomy type did not predict OS or DSS, recurrences, or complications. Conclusions: Median 3-year follow-up evaluating open versus robotic cystectomy demonstrates no differences with regard to OS, DSS, cancer recurrence or long-term complications. Although this study was not powered to assess survival differences, this is the first randomized study to report such data in a non-selected population with 3-year median follow-up.

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Pala, O., und P. Schrum. „SIMULATING INFRASTRUCTURE OUTAGES: AN OPEN-SOURCE GEOSPATIAL APPROACH“. ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-3/W4 (06.03.2018): 389–96. http://dx.doi.org/10.5194/isprs-archives-xlii-3-w4-389-2018.

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Abstract. Understanding the impact of service outages caused by natural or man-made disasters in utility services is a key part of decision-making in response and recovery efforts. Large-scale outages in the last 15 years, from the 2003 northeast blackout to Hurricane Maria devastating Puerto Rico in 2017, highlighted the importance of tight couplings within and across various utilities. The brittleness of these tight couplings results in long delays in restoring large-scale outages. Such cross-infrastructure effects can make analysis for decision makers and responders far more complex. To facilitate recovery, decision makers need to use specialized Decision Support Systems (DSS) that allow simulation of various alternative enablement options along with their impact on society. In this article, we describe our geo-simulation engine and datasets used for outage modelling. First, we detail our efforts in correcting and completing Electric Power (EP) network for the western US. Next, we explain the architecture and initial implementation of the platform-independent, open-source geospatial simulation engine that we are in the process of developing. Using this engine, we can consider the amount of commodity at the transmission source (power plants) and sinks (substations) and set thresholds at sinks to trigger and simulate outages. For instance, a threshold can be set to trigger an outage at substation level if the available commodity amount drops below 80&thinsp;% of the demand. Future additions include cross-infrastructure and enablement consequence analysis to provide a complete and transparent DSS to study outages on multiple interrelating infrastructures through scenario-based evaluation criteria.

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Mohktar, Mas S., Kezhang Lin, Stephen J. Redmond, Jim Basilakis und Nigel H. Lovell. „Design of a Decision Support System for a Home Telehealth Application“. International Journal of E-Health and Medical Communications 4, Nr. 3 (Juli 2013): 68–79. http://dx.doi.org/10.4018/jehmc.2013070105.

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A decision support system (DSS) that has been designed to manage patients using a home telehealth system is presented. The DSS has been developed to assist home telehealth clinical support staff with their workload, and to provide more effective communication between multiple home telehealth users. The three-tier system architecture that consists of a data layer; a business logic layer; and a front-end layer employs business processes and uses a rule engine for its logic and knowledge base. This paper discusses the design considerations involved in the construction of a DSS for the purpose of home telehealth, and illustrates how it may be developed using entirely open source software.

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Powar, Amit, Amol Gujar, Niketan Manthani, Vinayak Pawar und Rajkumar Singh. „Effect of Secondary Phase Precipitation on Impact Toughness of Duplex Stainless Steel“. Materials Science Forum 889 (März 2017): 138–42. http://dx.doi.org/10.4028/www.scientific.net/msf.889.138.

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Duplex Stainless Steel (DSS) combines good mechanical strength and ductility with moderate to good corrosion resistance in a variety of environments. DSS are prone to the formation of various intermetallic phases (σ, χ, π, R), carbides (M23C6) and nitrides (Cr2N), when it exposed to temperatures lower than 1000°C. This study focuses on effect of secondary phase precipitation on impact toughness of ASTM A182 DSS. Cylindrical bar of DSS was open die forged in the temperature range of 1200-1050°C. After the forging, the bar was slow cooled by covering it with ceramic wool. This leads to the formation of σ phase at the ferrite/austenite interfaces and significantly reduced the impact toughness of the material. Solution treatment was done at different temperature and effect on toughness studied. The microstructural changes produced as consequences of the distinct test condition have been analyzed by means of optical and electron microscopy, X-ray diffraction.

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Horak, J., A. Orlik und J. Stromsky. „Web services for distributed and interoperable hydro-information systems“. Hydrology and Earth System Sciences 12, Nr. 2 (25.03.2008): 635–44. http://dx.doi.org/10.5194/hess-12-635-2008.

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Abstract. Web services support the integration and interoperability of Web-based applications and enable machine-to-machine interaction. The concepts of web services and open distributed architecture were applied to the development of T-DSS, the prototype customised for web based hydro-information systems. T-DSS provides mapping services, database related services and access to remote components, with special emphasis placed on the output flexibility (e.g. multilingualism), where SOAP web services are mainly used for communication. The remote components are represented above all by remote data and mapping services (e.g. meteorological predictions), modelling and analytical systems (currently HEC-HMS, MODFLOW and additional utilities), which support decision making in water management.

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Horak, J., A. Orlik und J. Stromsky. „Web services for distributed and interoperable hydro-information systems“. Hydrology and Earth System Sciences Discussions 4, Nr. 3 (26.06.2007): 1879–91. http://dx.doi.org/10.5194/hessd-4-1879-2007.

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Abstract. Web services support the integration and interoperability of Web-based applications and enable machine-to-machine interaction. The concepts of web services and open distributed architecture were applied to the development of T-DSS, the prototype customised for web based hydro-information systems. T-DSS provides mapping services, database related services and access to remote components, with special emphasis placed on output flexibility (e.g. multilingualism), where SOAP web services are mainly used for communication. The remote components are represented above all by distant data and mapping services (e.g. eteorological predictions), modelling and analytical systems (currently HEC-HMS, Modflow and additional utilities), which support decision making in water management.

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Estanyol, Francesc, Xavier Rafael, Roman Roset, Miguel Lurgi, Mariola Mier und Magi Lluch-Ariet. „A Web-accessible distributed data warehouse for brain tumour diagnosis“. Knowledge Engineering Review 26, Nr. 3 (28.07.2011): 329–51. http://dx.doi.org/10.1017/s0269888911000142.

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AbstractCurrently, biological databases (DBs) are a common tool to complement the research of a wide range of biomedical disciplines, but there are only a few specialized medical DBs for human brain tumour magnetic resonance spectroscopy (MRS) data; they typically store a limited range of biological data (i.e. clinical information, magnetic resonance imaging and MRS data) and are not offered as open-source Structured Query Language relational DB schemas. We present a novel approach to biological DBs: a distributed Web-accessible DB for storing and managing clinical and biomedical data related to brain tumours from different clinical centres. This tool is designed for multi-platform systems with dissimilar DB management systems. Being the main data repository of the HealthAgents (HA) project, it uses multi-agent technology and allows the centres to share data and obtain diagnosis classifications from other centres distributed around the world in a reliable way.The HA project aims to create an agent-based distributed decision support system (DSS) to assist doctors to provide a brain tumour diagnosis and prognosis. The HA DB enables the DSS to totally integrate with its Graphical User Interface to perform classifications with the stored data and visualize the results using the HA distributed agents framework. This new feature converts the system presented in the first application in the world to combine a storage and management tool for brain tumour data and a complete Web-based DSS to obtain automatic diagnosis.

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Del Bon, Francesca, Cesare Piazza, Davide Lancini, Alberto Paderno, Paolo Bosio, Stefano Taboni, Riccardo Morello et al. „Open Partial Horizontal Laryngectomies for T3–T4 Laryngeal Cancer: Prognostic Impact of Anterior vs. Posterior Laryngeal Compartmentalization“. Cancers 11, Nr. 3 (01.03.2019): 289. http://dx.doi.org/10.3390/cancers11030289.

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Open partial horizontal laryngectomies (OPHLs) are well-established and oncologically safe procedures for intermediate–advanced laryngeal cancers (LC). T–N categories are well-known prognosticators: herein we tested if “anterior” vs. “posterior” tumor location (as defined in respect to the paraglottic space divided according to a plane passing through the arytenoid vocal process, perpendicular to the ipsilateral thyroid lamina) may represent an additional prognostic factor. We analyzed a retrospective cohort of 85 T3–4a glottic LCs, treated by Type II or III OPHL (according to the European Laryngological Society classification) from 2005 to 2017 at two academic institutions. Five-year overall survival (OS), disease-specific survivals (DSS), and recurrence-free survivals (RFS) were compared according to tumor location and pT category. Anterior and posterior tumors were 43.5% and 56.5%, respectively, 78.8% of lesions were T3 and 21.2% were T4a. Five-year OS, DSS, and RFS for T3 were 74.1%, 80.5%, and 63.4%, respectively, and for T4a 71.8%, 71.8%, and 43%, respectively (p not significant). In relation to tumor location, the survival outcomes were 91%, 94.1%, and 72.6%, respectively, for anterior tumors, and 60.3%, 66.3%, and 49.1%, respectively, for posterior lesions (statistically significant differences). These data provide evidence that laryngeal compartmentalization is a valid prognosticator, even more powerful than the pT category.

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Mora, Manuel, Fen Wang, Ovsei Gelman und Miroljub Kljajic. „IDSSE-M“. International Journal of Decision Support System Technology 3, Nr. 4 (Oktober 2011): 55–84. http://dx.doi.org/10.4018/jdsst.2011100104.

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Decision-making Support Systems (DMSSs) have been traditionally designed and built by using mainly the Waterfall method, Prototyping-Evolutive, or Adaptive approach in the last three decades. In this paper, the authors argue that while such approaches have guided to DMSS developers, they have been also demanded for adding ad-hoc, non-standardized activities and extra techniques based on their own expertise due to the scarcity of open-access available information of them. Additionally, from a Software Systems Engineering (SSE) viewpoint, such approaches cannot be considered as well-defined methodologies. This article contributes to the research stream of SSE-based DMSS development methodologies by reporting an initial empirical evaluation of IDSSE-M, a free-access methodology for designing and building Intelligent Decision Support Systems. IDSSE-M extends and adapts Turban and Aronson’s DSS Building Paradigm (open access), and Saxena’s Decision Support Engineering Methodology (proprietary). IDSSE-M offers DMSS developers at least a moderate level of usefulness, compatibility, and results demonstrability, which leads to a positive, good and beneficial attitude of using the methodology.

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De Virgilio, A., A. Greco, F. Bussu, A. Gallo, D. Rosati, S. H. Kim, C. C. Wang, M. Conte, G. Pagliuca und M. De Vincentiis. „ACTA OTORHINOLARYNGOLOGICA ITALICA“. Acta Otorhinolaryngologica Italica 36, Nr. 5 (Oktober 2016): 373–80. http://dx.doi.org/10.14639/0392-100x-749.

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Lo scopo del presente studio è stato quello di valutare lefficacia oncologica della laringectomia totale di salvataggio in pazienti precedentemente sottoposti a laringectomia subtotale open o microchirurgia laser transorale affetti da carcinoma squamocellulare laringeo. Abbiamo analizzato retrospettivamente le informazioni cliniche, chirurgiche e patologiche di 35 pazienti sottoposti a laringectomia totale di salvataggio dopo recidiva di carcinoma laringeo (laringectomia subtotale open o transorale). Le informazioni sono state analizzate tramite lutilizzo delle curve di Kaplan-Meier nonché tramite lanalisi univariata e multivariata dei fattori prognostici. Non sono emerse differenze statisticamente significative nel confronto tra il gruppo di pazienti precedentemente sottoposti a laringectomia subtotale ed il gruppo sottoposto a microchirurgia laser transorale sia in termini di overall survival (OS) e disease specific survival (DSS) a 3 anni (OS = 38% vs 52%, p = 0,16; DSS = 40% vs 61%, p = 0,057) che di controllo locoregionale (LRC) a 2 anni (LRC = 40% vs 54%, p = 0,056). È stata tuttavia messa in evidenza una tendenza che indica una sopravvivenza e controllo locoregionale peggiore nei pazienti sottoposti a laringectomia subtotale. La conservazione dello scheletro osteocartilagineo della microchirurgia laser transorale si traduce ipoteticamente in una maggiore probabilità di salvataggio delle recidive anteriori con diffusione extralaringea.

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Miller, Heather J., Pedro de Alba und Kenneth C. Baldwin. „Cyclic Simple Shear Apparatus for Low-Strain Soil Tests“. Transportation Research Record: Journal of the Transportation Research Board 1548, Nr. 1 (Januar 1996): 9–15. http://dx.doi.org/10.1177/0361198196154800102.

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A testing system has been developed to study the behavior of saturated sand under low-level cyclic shearing strains. The system has been used to determine threshold shear strain levels for fabric destruction in sand aged for different time periods. The system includes a special soil chamber and a direct simple shear (DSS) machine. To impose very small shearing strains, the DSS machine was designed to apply and measure horizontal deformations as small as 0.0005 mm (2 × 10−5 inches). Data obtained to date support the results of previous investigators who performed triaxial tests on freshly deposited samples, indicating a threshold cyclic shear strain level of approximately 0.01 percent. At strains in excess of those levels, destruction of the sand fabric occurred, as evidenced by a reduction in shear modulus at low strain levels. Subsequent modest increases in shear modulus were observed after the specimens were allowed to recover for 24 hours and then tested again. During the recovery period, drainage valves were left open to allow for dissipation of excess pore pressures and for potential consolidation during the short aging period. The DSS system was found to work well for low strain measurements. Furthermore, since shear strains are measured directly under DSS conditions (as opposed to triaxial conditions), the DSS system shows much promise as a device for studying parameters that may influence threshold shear strain levels and fabric evolution and destruction in sands.

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Ahmad, Shahryar Khalique, und Faisal Hossain. „A web-based decision support system for smart dam operations using weather forecasts“. Journal of Hydroinformatics 21, Nr. 5 (04.07.2019): 687–707. http://dx.doi.org/10.2166/hydro.2019.116.

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Abstract A web-based open-source decision support system (DSS) was developed to facilitate real-world engagement with dam-operating agencies in the decision-making process involving atmospheric modeling, hydrologic modeling, and web technology. The development process was decoupled into the container (frontend) and the modeling framework for the content (backend), to arrive at an intelligent system that improves the productivity and independent reuse of each component. The backend framework uses the weather forecasts from Numerical Weather Prediction models, downscales to a finer resolution, and simulates hydrologic and data-based artificial neural network models to optimize operations. The frontend architecture disseminates the forecasted meteorological variables, reservoir inflow, optimized operations, and retrospective weekly assessment of forecasts and hydropower benefits. The framework is automated and operationalized over the Detroit dam (Oregon) to generate the daily optimized release decisions. However, backend scripts and frontend elements are flexible and customizable enough that the DSS can be reproduced for other dams. The optimization of reservoir operations based on weather forecasts results in significant additional hydropower benefit without compromising other objectives when compared to the conventional operations. More importantly, the platform helps visualize for the dam operator how much more ‘smarter’ operations can be if weather forecasts and open-source technology are used.

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Kozlov, V. V., T. V. Tomashevska und N. I. Kuznetsov. „Using of Optimization Models in Financial Decision Support Systems“. Statistics of Ukraine 88, Nr. 1 (01.05.2020): 75–83. http://dx.doi.org/10.31767/su.1(88)2020.01.09.

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The article discusses the use of optimization models in financial decision support systems (DSS). The architecture of the DSS is considered. It is determined by the nature of the interaction of its main components: the user interface, database and data warehouse, documents and rules, models and analytical tools, communications infrastructure and networks, as well as elements of these parts. The architecture of the DSS for solving problems of financial management is determined by the nature of interaction of its main components. Conceptual and functional models are presented. The functional model of the DSS reflects the structure of control actions on decision-makers, persons involved in the implementation of corrective actions necessary for effective financial performance. According to the functional model, a block diagram of the DSS is proposed. The block diagram of decision support consists of three main subsystems and provides modular-block construction. The proposed system is characterized by an open architecture and can be easily modified for functional expansion or for connecting and using external databases. The DSS should provide a common operating environment for modeling objects in a dynamically changing economic situation. The operating environment contains basic calculation algorithms, and allows the user to create own algorithms for calculating cash flows and used indicators. Thus, the key element of the integrated decision support system for managing the financial condition of the enterprise is the models laid down in the basis of the system. The architecture of the DSS based on algorithms is considered. A DSS of this type contains a set of algorithms for solving a selected class of problems. Of the factors that influence the choice of a specific architecture of the DSS in financial management, we can highlight (i) the need for further development of the system, (ii) its adaptation, and (iii) the application of the evolutionary approach to the development of the DSS. The components of the system are: data input component, resource allocation component, strategy selection component, output component. The resource allocation component contains the following sub-components: determination of dependence coefficients, solution of optimization problem, solution of equation. The strategy selection component includes the sub-components for calculating the values of integral design characteristics, for calculating the values of groups of design characteristics, and for the pairwise comparison of strategies. The information model of the component “The distribution of financial resources of the enterprise” is presented. The DSS performs data processing and checks for critical decision characteristics. The formalized structure of the algorithm for using the proposed models of distribution of financial resources, types of model integration are considered.

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Manthey, L., und D. M. Popov. „Driver Safety System Implementation in Europe“. Mining Science and Technology 4, Nr. 4 (30.01.2020): 302–8. http://dx.doi.org/10.17073/2500-0632-2019-4-302-308.

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In mining industry safety is top priority. There is a request for safety management, risk prevention and operator training. Operator fatigue and distraction leads to dangerous situations. The paper is aimed at reviewing the issues of fatigued or distracted driver operation. This is achieved through creating models in occupational safety strategies. Hereafter the implementation of fatigue and distraction control system within a pilot project is discussed. The pilot project was aimed at collecting realistic operation data from mining industry in Europe. Caterpillar Inc. offers a solution called Driver Safety System (DSS). When driver’s micro-sleep is detected, the system alerts operator through different alarms directly. Dangerous events are also recorded and classified individually in 24/7 monitoring centre. The DSS was tested at European limestone open pit mine with typical working regime. This paper discusses theories, results and transferable insights of the study.

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Lv, Wei-jie, Cui Liu, Lin-zeng Yu, Jia-hao Zhou, Yue Li, Ying Xiong, Ao Guo et al. „Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats“. Oxidative Medicine and Cellular Longevity 2020 (31.07.2020): 1–17. http://dx.doi.org/10.1155/2020/1241894.

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There is a bidirectional relationship between inflammatory bowel disease (IBD) and depression/anxiety. Emerging evidences indicate that the liver may be involved in microbiota-gut-brain axis. This experiment focused on the role of melatonin in regulating the gut microbiota and explores its mechanism on dextran sulphate sodium- (DSS-) induced neuroinflammation and liver injury. Long-term DSS-treatment increased lipopolysaccharide (LPS), proinflammation cytokines IL-1β and TNF-α, and gut leak in rats, breaking blood-brain barrier and overactivated astrocytes and microglia. Ultimately, the rats showed depression-like behavior, including reduction of sucrose preference and central time in open field test and elevation of immobility time in a forced swimming test. Oral administration with melatonin alleviated neuroinflammation and depression-like behaviors. However, melatonin supplementation did not decrease the level of LPS but increase short-chain fatty acid (SCFA) production to protect DSS-induced neuroinflammation. Additionally, western blotting analysis suggested that signaling pathways farnesoid X receptor-fibroblast growth factor 15 (FXR-FGF 15) in gut and apoptosis signal-regulating kinase 1 (ASK1) in the liver overactivated in DSS-treated rats, indicating liver metabolic disorder. Supplementation with melatonin markedly inhibited the activation of these two signaling pathways and its downstream p38. As for the gut microbiota, we found that immune response- and SCFA production-related microbiota, like Lactobacillus and Clostridium significantly increased, while bile salt hydrolase activity-related microbiota, like Streptococcus and Enterococcus, significantly decreased after melatonin supplementation. These altered microbiota were consistent with the alleviation of neuroinflammation and metabolic disorder. Taken together, our findings suggest melatonin contributes to reshape gut microbiota and improves inflammatory processes in the hippocampus (HPC) and metabolic disorders in the liver of DSS rats.

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Melcalfe, Michael, Wassim Kassouf, Ricardo Rendon, David Bell, Jonathan Izawa, Joseph Chin, Anil Kapoor et al. „Regional differences in practice patterns and associated outcomes for upper tract urothelial carcinoma in Canada“. Canadian Urological Association Journal 6, Nr. 6 (13.12.2012): 455. http://dx.doi.org/10.5489/cuaj.116.

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Introduction: We delineated Canadian regional differences in practice patterns in the management of upper tract urothelial carcinoma (UTUC) after nephroureterectomy and relate these to patient outcomes.Methods: A database was created with 1029 patients undergoing radical nephroureterectomy for UTUC between 1994 and 2009 at 10 Canadian centres. Demographic, clinical and pathological variables were collected from chart review. Practice pattern variables were defined as: open versus laparoscopic nephroureterectomy, management strategy for the distal ureter, performance of lymphadenectomy and administration of chemotherapy and/or radiation therapy. The outcome measures were overall (OS), disease-specific (DSS) and recurrence-free survival (RFS). The centres were divided into three regions (West, Central, East). Cox proportional multivariable linear regression analysis was used to determine the association between regional differences in practice patterns and clinical outcomes.Results: There was a significant difference in practice patterns between regions within Canada for: time from diagnosis to surgery (p = 0.001), type of surgery (open vs. laparoscopic, p < 0.01) and method of management of the distal ureter (p = 0.001). As well, there were significant differences in survival between regions across Canada: 5-year OS (West 70%, Central 81% and East 62%, p < 0.0001) and DSS (West=79%, Central=85%, East=75%, p = 0.007) were significantly different, but there was no difference in RFS (West 47%, Central 48%, East 46%, p = 0.88). Multivariable linear regression analysis demonstrated that the differences in survival were independent of region OS (p = 0.78), DSS (p = 0.30) or RFS (p = 0.43).Conclusion: There is significant disparity in practice patterns between regions within Canada, but these do not appear to have an effect on survival. We believe that the variability in practice is a reflection of the lack of standardized treatments for UTUC and underlines the need for multi-institutional studies in this disease.

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Huang, Yuan Jiang, und Jie Huang. „The Study on Fire Spreading Based on Mobile Agent and Grid Technology“. Advanced Materials Research 971-973 (Juni 2014): 1834–37. http://dx.doi.org/10.4028/www.scientific.net/amr.971-973.1834.

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In order to build a truly open OpenDSS and enhance the complexity of decision-making DSS for solving the problem of Fire spreading. a new model was given based on mobile Agent Open Decision Support System in grid environment. Making use of the intelligence of MAS and adaptive capacity, based on the reasoning mechanisms for task decomposition and resource decision-making grid matching, described in detail layer program CBR-based reasoning mechanism of the Agent and its operation flow and interactive mechanism, put the complexity of distribution of decision-making problem solving to the grid nodes on the environment, implementation of parallel asynchronous decision-making problem solving. Optimize distribution through the logistics of the problem MABODSS design, it proved to improve the system's intelligence and operational efficiency.

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Shibata, Seiko, Hitoshi Kagaya, Yasunori Ozeki, Eiichi Saitoh, Yoichiro Aoyagi, Yoshihiro Iwata und Kazuo Sakurai. „Effect of Laryngeal Suspension and Upper Esophageal Sphincter Myotomy for Severe Dysphagia Due to Brainstem Disease“. Annals of Otology, Rhinology & Laryngology 129, Nr. 7 (10.02.2020): 689–94. http://dx.doi.org/10.1177/0003489420904741.

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Objectives: Surgical procedure is considered in patients with severe dysphagia when conservative treatment fails. This study aimed to evaluate laryngeal suspension (LS) and upper esophageal sphincter (UES) myotomy for treating severe dysphagia due to brain disease. Methods: Fourteen patients underwent LS and UES myotomy, with a median follow-up of 5 years and 6 months when conservative treatment failed. The penetration-aspiration scale (PAS), the Dysphagia Severity Scale (DSS), the Eating Status Scale (ESS), and diet contents were evaluated just before surgery, at discharge, and at the last follow-up. Results: Preoperative intake was tube feeding in all patients. The patients learned the extended head and flexed neck posture to open the esophageal inlet. PAS, DSS and ESS scores, and diet contents were significantly improved at discharge compared with before surgery, and were maintained until the last follow-up. Eight patients had pneumonia during their hospital stay, and five had pneumonia between discharge and at the last follow-up. Age was significantly, negatively correlated with DSS and ESS at the last follow-up. Conclusion: Although LS and UES myotomy require a long inpatient rehabilitation and the risk of pneumonia after surgery is high, the outcome is favorable and the effects last for a long time.

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Mmeje, C., R. Nunez-Nateras, R. Pruthi, M. E. Nielsen, E. Wallen, M. Humphreys und E. P. Castle. „Oncologic outcomes for node-positive patients undergoing robotic radical cystectomy.“ Journal of Clinical Oncology 29, Nr. 7_suppl (01.03.2011): 290. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.290.

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290 Background: Previous studies have shown robot assisted radical cystectomy (RARC) to have equivalent perioperative outcomes to open radical cystectomy. There are few reports that have examined the oncologic results of RARC specifically with respect to node-positive patients. We report the outcomes of node-positive patients who have undergone RARC with medium-term (at least 1 year) follow-up. Methods: A total of 275 patients underwent RARC at two institutions for invasive bladder cancer between 2005-present. We examined the 50 patients with node-positive disease that had a minimum of one year follow-up. Oncologic outcomes, recurrence free survival (RFS), and disease specific survival (DSS) were analyzed and compared to the open literature. Results: Mean clinical follow up in this case series was 29 months (range 12–64 months). The mean number of lymph nodes removed was 18 (range 5–35), and mean number of positive LNs was 3.1 (range 1–12). Overall rate of LN positivity was 26%. Mean LN density was 18%. Seventeen (34%) patients had ≤ pT2 disease and 33 (66%) pT3/T4 disease. At this follow-up, 29 patients have recurred, 21 patients died of disease, giving a RFS and DSS of 42% and 58%, respectively. Mean (median) time to recurrence was 10.2 months (9 months). A total of 60% of patients received peri-operative chemotherapy in this cohort. These findings are consistent with prior reports of such oncologic outcomes in node-positive patients in open series. Conclusions: The oncologic follow-up of patients undergoing RARC with LN positive disease appears to have acceptable outcomes during medium term (mean 29 months) follow-up. As our follow-up increases, we expect to continue to accurately define the long-term clinical suitability and oncologic success of this procedure in this high-risk population. No significant financial relationships to disclose.

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Wei, Daneng, Na Zhao, Lushuang Xie, Biao Huang, Zhiqi Zhuang, Yong Tang, Shuguang Yu und Qiaofeng Wu. „Electroacupuncture and Moxibustion Improved Anxiety Behavior in DSS-Induced Colitis Mice“. Gastroenterology Research and Practice 2019 (07.02.2019): 1–12. http://dx.doi.org/10.1155/2019/2345890.

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Background and Aims. Psychological disorders are prevalent in patients with inflammatory bowel disease, but the underlying mechanisms remain unknown. The aim of this study was to study whether electroacupuncture (EA) and moxibustion (MB) can improve anxiety behavior in DSS-induced colitis mice and to investigate whether this effect is related to hypothalamic-pituitary-adrenocortical (HPA) axis. Methods. The colitis model was established by drinking 2.5% dextran sodium sulfate (DSS). DSS-induced colitis mice were treated by EA or MB. Disease activity index (DAI) was scored; intestinal morphological and pathological structure was observed; anxiety behavior was tested by the elevated plus maze and open field. The concentration of corticotropin-releasing hormone (CRH) and cortisol (CORT) in serum was measured by enzyme-linked immunosorbent assay (ELISA). The protein expression of CRH in the colon and hypothalamus was detected by Western blot (WB). Results. Both EA and MB treatments can improvethe morphology of their distal colonic mucosal epithelia, as well as the disease activity index. Meanwhile, anxiety behavior in colitis mice was improved slightly after EA and MB treatment. In addition, the levels of CRH and CORT in the serum were slightly improved after EA and MB treatment. These effects are further supported by WB results. The expression of CRH in the colon and hypothalamus was increased significantly after treatment, compared with the model group. Conclusion. EA and MB were able to regulate the concentration of CRH in serum and protein expression in the peripheral and central at different levels and promote the recovery of the HPA axis that may be the basis for EA and MB to improve colonic pathology and alleviate anxiety behavior in DSS-induced colitis.

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Tran Thi Thuy, Tien, Krishnan Kannoorpatti, Anna Padovan und Suresh Thennadil. „Effect of Alkaline Artificial Seawater Environment on the Corrosion Behaviour of Duplex Stainless Steel 2205“. Applied Sciences 10, Nr. 15 (22.07.2020): 5043. http://dx.doi.org/10.3390/app10155043.

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Sulphate reducing bacteria (SRB) can be found in alkaline environments. Due to their metabolite products such as hydrogen sulphide, the corrosion behaviour of materials in alkaline environments may be affected by the presence of SRB. This study focuses on the investigation of corrosion behaviour of duplex stainless steel DSS 2205 in nutrient rich artificial seawater containing SRB species, Desulfovibrio vulgaris, at different alkaline conditions with pH range from 7 to 10. The open circuit potential value (OCP), sulphide level and pH were recorded daily. Confocal laser scanning microscopy (CLSM) was used to study the adhesion of SRB on the DSS 2205 surface. Electrochemical impedance spectroscopy (EIS) was used to study the properties of the biofilm. Potentiodynamic polarization was used to study the corrosion behaviour of material. Inductively coupled plasma mass was used to measure the concentration of cations Fe, Ni, Mo, Mn in the experimental solution after 28 days. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) were used for surface analysis. The results showed that D. vulgaris are active in an alkaline environment with pH 7–9. However, at pH 10, D. vulgaris activity exhibited an 8-day lag. The corrosion rate of DSS 2205 at pH 9 was higher than at other pH environments due to a higher dissolved concentration of hydrogen sulphide.

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Dwyer, Johanna T., und Paul M. Coates. „Why Americans Need Information on Dietary Supplements“. Journal of Nutrition 148, suppl_2 (01.08.2018): 1401S—1405S. http://dx.doi.org/10.1093/jn/nxy081.

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Abstract Until a decade ago, no dietary supplement (DS) databases with open access for public use existed in the United States. They were needed by researchers, since half of American adults use dietary DSs and, without information on supplement use and composition, exposures could not be estimated. These articles on Challenges and Future Directions for Dietary Supplement Databases describe subsequent progress. They begin by describing why information on DSs is needed by the government and how it is used to ensure the health of the public. Current developments include: application of DS information to meet public health needs; research efforts on DS quality, efficacy, and safety (as conducted by the Office of Dietary Supplements and other federal agencies); enhanced regulatory activities implemented by the FDA Office of Dietary Supplement Programs, the FDA Office of Enforcement, and the Federal Trade Commission; and initiatives for broader development and dissemination of DS databases for commercial and public use. Other contributions in this journal supplement describe the challenges of working with DSs and the progress that has been made. Additional articles describe surveys of DS use among the general US population and also among special groups such as high supplement users, illustrating why there is a need in the United States for information on supplements. Likely directions for the future of DS science are summarized.

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RODRIGUEZ-BACHILLER, AGUSTIN. „GEOGRAPHICAL INFORMATION SYSTEMS AND EXPERT SYSTEMS FOR IMPACT ASSESSMENT Part II: Expert Systems and Decision Support Systems“. Journal of Environmental Assessment Policy and Management 02, Nr. 03 (September 2000): 415–48. http://dx.doi.org/10.1142/s1464333200000424.

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This paper and another one preceding it investigate the potential of computer technologies like Geographical Information Systems (GIS) and Expert Systems (ES) to help with Impact Assessment (IA), suggesting that one way to optimise the effectiveness of GIS is to embed these systems in a more user-friendly environment. This paper explores the experience and potential of ES to provide such decision support environment, extending the argument further into the realm of Decision Support Systems (DSS). The proposition behind this paper is that these areas (IA, GIS, ES and maybe DSS) are potentially complementary and there can be mutual benefits if they are brought together. Certain tasks in IA — like screening, scoping, or statement review — already have potential for substantial automation, as an opportunity for technology transfer within organisations involved with IA, so that relatively scarce experts can be freed up for more difficult jobs while less expert staff are promoted to answer more sophisticated questions like these. More technical tasks like impact and environmental prediction also show scope for some degree of modelling-based automation, while other less routinised and more open-ended tasks involved with the management of the whole IA process probably lend themselves better to automation of a different kind, which works more as an "aid" than a substitute for the expert, for which the more flexible DSS seem more appropriate.

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Sandeep, K., und K. Rakesh. „CLIPS based decision support system for water distribution networks“. Drinking Water Engineering and Science 4, Nr. 1 (27.10.2011): 37–50. http://dx.doi.org/10.5194/dwes-4-37-2011.

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Abstract. The difficulty in knowledge representation of a water distribution network (WDN) problem has contributed to the limited use of artificial intelligence (AI) based expert systems (ES) in the management of these networks. This paper presents a design of a Decision Support System (DSS) that facilitates "on-demand'' knowledge generation by utilizing results of simulation runs of a suitably calibrated and validated hydraulic model of an existing aged WDN corresponding to emergent or even hypothetical but likely scenarios. The DSS augments the capability of a conventional expert system by integrating together the hydraulic modelling features with heuristics based knowledge of experts under a common, rules based, expert shell named CLIPS (C Language Integrated Production System). In contrast to previous ES, the knowledge base of the DSS has been designed to be dynamic by superimposing CLIPS on Structured Query Language (SQL). The proposed ES has an inbuilt calibration module that enables calibration of an existing (aged) WDN for the unknown, and unobservable, Hazen-Williams C-values. In addition, the daily run and simulation modules of the proposed ES further enable the CLIPS inference engine to evaluate the network performance for any emergent or suggested test scenarios. An additional feature of the proposed design is that the DSS integrates computational platforms such as MATLAB, open source Geographical Information System (GIS), and a relational database management system (RDBMS) working under the umbrella of the Microsoft Visual Studio based common user interface. The paper also discusses implementation of the proposed framework on a case study and clearly demonstrates the utility of the application as an able aide for effective management of the study network.

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Vongsilathai, Songkran, Anchaleeporn Waritswat Lothongkum und Gobboon Lothongkum. „Corrosion behavior of a new 25Cr-3Ni-7Mn-0.66 N duplex stainless steel in artificial seawater“. Materials Testing 63, Nr. 6 (01.06.2021): 505–11. http://dx.doi.org/10.1515/mt-2020-0086.

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Abstract A new duplex 25Cr-3Ni-7Mn-0.66 N alloy was prepared in a vacuum arc re-melting furnace and characterized by metallographic and EPMA methods. Its corrosion behavior was investigated by potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) and a Mott-Schottky (M-S) analysis in artificial seawater at room temperature and compared with those of super and normal commercial duplex stainless steel (SDSS and DSS). No significant difference in the open circuit potentials and pitting potentials was observed. Its passive film current density lies between those of SDSS and DSS. This was confirmed by EIS analysis. A pit attack was observed on the δ-phase for all duplex samples, because the PREN16 of the δ-phase was lower than that of the γ-phase. From the Mott-Schottky analysis, the passive films were found to be composed of bi-layer structures, a p-type semiconductor inner layer, and a n-type semiconductor outer layer. The degree of defect as well as the effect of nitrogen in passive film layer are discussed with respect to the point defect model.

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Tran, Thi Thuy Tien, Krishnan Kannoorpatti, Anna Padovan, Suresh Thennadil und Khai Nguyen. „Microbial corrosion of DSS 2205 in an acidic chloride environment under continuous flow“. PLOS ONE 16, Nr. 5 (12.05.2021): e0251524. http://dx.doi.org/10.1371/journal.pone.0251524.

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Corrosion under flow conditions is a major problem in the transportation industry. Various studies have shown the direct impact of different flow rates on bacteria biofilm formation, mass transfer and resulting different corrosion behaviour of materials in neutral environments. However, little is understood on corrosion under acidic flow conditions. This study investigated the impact of an acidic artificial seawater environment containing Desulfovibrio vulgaris on DSS 2205 microbial corrosion under different velocities (0.25 m.s-1 and 0.61 m.s-1). Experiments containing no bacteria were performed as controls. Bacterial attachment was observed by optical and scanning electron microscope (SEM). Materials corrosion was assessed using open circuit potential (OCP), electrochemical impedance spectroscopy (EIS) and potentiodynamic polarization. Pits formed after potentiodynamic test were observed under SEM. The largest area of bacterial attachment was found on coupons immersed at a velocity of 0.25 m.s-1; however, the corrosion rate was lower than at higher velocity. Shallow pits occurred in the metal coupons when bacteria were present, while deep pits occurred in the controls. The study indicates the positive impact of biofilm formation in corrosion prevention of materials under acidic condition. The nature of corrosion behaviour of duplex stainless is discussed.

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Mitraka, Zina, Sofia Siachalou, Georgia Doxani und Petros Patias. „Decision Support on Monitoring and Disaster Management in Agriculture with Copernicus Sentinel Applications“. Sustainability 12, Nr. 3 (08.02.2020): 1233. http://dx.doi.org/10.3390/su12031233.

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The successful implementation of the European Commission’s Common Agricultural Policy (CAP) and the insurance coverage in case of a natural disaster requires precise and regular mapping of crop types and detailed delineation of the disasters’ effects by frequent and accurate controls. Free and open access policy to Copernicus Sentinel data offers a big volume of data to the users on a consistent and complete basis. Today, the Sentinels are involved in an increasing number of agriculture applications, but their effective exploitation is still being investigated and the development of efficient tools, aligned to the user’s needs, is yet to be realised. To this end, the DiAS (Disaster and Agriculture Sentinel Applications) project proposes methods for decision support in agriculture using Sentinel data for crop type mapping, as well as mapping of the extend of fire and flood effects in agricultural areas. The DiAS Decision Support System (DSS) is designed in consultation with potential users in participatory approach and aims to provide a prototype tool, which provides assistance to the responsible paying agencies and insurance organizations to make decisions on farmers’ subsidies and compensations. The DiAS DSS prototype and its functionalities are presented in this paper and its use is demonstrated through example applications for two test sites in Greece. The DiAS DSS demonstrates the necessity for the development of similar tools, as this emerges from the user’s requirements, and wishes to stimulate and inspire further research and development.

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Gallo, Oreste, Angelo Cannavicci, Chiara Bruno, Giandomenico Maggiore und Luca Giovanni Locatello. „Survival Outcomes and Prognostic Factors of Open Partial Laryngeal Surgery: A Thirty Years’ Experience“. Annals of Otology, Rhinology & Laryngology 129, Nr. 7 (06.02.2020): 669–76. http://dx.doi.org/10.1177/0003489420905616.

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Background: Open partial laryngeal surgery (OPLS) represents a wide array of procedures that can be fitted to treat different types of laryngeal cancer (LC). We would like to present our 30-years’ institutional experience, to analyze survival outcomes and to critically discuss prognostic factors. Methods: We reviewed all cases of OPLS performed at our Institution from 1982 to 2016 for LC. Survival analysis by Kaplan–Meier estimate was performed and prognostic variables by multivariate analysis were identified. Results: Mean follow-up time was 68.3 months, 30-day mortality 0.2%, subsequent functional total laryngectomy (TL) was 1.01%. Over 80% of cases were stage I to II. We had 25 local, 62 regional and eight distant recurrences. Local control was 94.9%, overall survival (OS) was 83.4% and disease-specific survival (DSS) was 87.7%. The two major risk factors significantly associated with the risk of death were cT and cN stage. CONCLUSIONS: We have confirmed that OPLS represents an oncologically sound option in the treatment of LC despite the emergence of non-surgical strategies and new transoral mininvasive techniques. Our results highlight that accurate staging, correct selection of the patient and a strong surgical expertise are of paramount importance in this type of surgery.

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Tann, Wei, und Heiu-Jou Shaw. „Constructing Web-Based Object-Oriented Design Support System for Collaborative Ship Modeling“. Marine Technology and SNAME News 44, Nr. 03 (01.07.2007): 139–50. http://dx.doi.org/10.5957/mt1.2007.44.3.139.

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Multidiscipline three-dimensional (3D) design tools are utilized by most advanced shipyards in the world to gain both competitive advantage and productivity. While deadlines become shorter and shorter, the complexity of modern commercial vessels increases steadily; therefore, it is imperative for the marine industry to integrate diverse engineering information systems. 3D models are repetitiously constructed mainly because specified requirements on different design stages are time-consuming. In order to supersede costly point-to-point integration or system-specific integration that have been used, much attention has been paid to develop the advanced and open platform to not only codevelop parts by designers at different geographical locations, coordinate dissimilar applications and application components, but facilitate connectivity and the overall communication process to provide the end user with integrated and consistent data. This paper describes the object-oriented data-sharing collaborative design support system (DSS). DSS is proposed to speed up the construction of 3D models by the Internet technologies to translate product data and further be capable of providing reasonable model configurations of XML descriptions and sharing Web Services on the Internet to comply with shipyards' specific strategies.

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Wirsing, Anna Maria, Inger-Heidi Bjerkli, Sonja Eriksson Steigen, Oddveig Rikardsen, Synnøve Norvoll Magnussen, Beate Hegge, Marit Seppola, Lars Uhlin-Hansen und Elin Hadler-Olsen. „Validation of Selected Head and Neck Cancer Prognostic Markers from the Pathology Atlas in an Oral Tongue Cancer Cohort“. Cancers 13, Nr. 10 (14.05.2021): 2387. http://dx.doi.org/10.3390/cancers13102387.

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The Pathology Atlas is an open-access database that reports the prognostic value of protein-coding transcripts in 17 cancers, including head and neck cancer. However, cancers of the various head and neck anatomical sites are specific biological entities. Thus, the aim of the present study was to validate promising prognostic markers for head and neck cancer reported in the Pathology Atlas in oral tongue squamous cell carcinoma (OTSCC). We selected three promising markers from the Pathology Atlas (CALML5, CD59, LIMA1), and analyzed their prognostic value in a Norwegian OTSCC cohort comprising 121 patients. We correlated target protein and mRNA expression in formalin-fixed, paraffin-embedded cancer tissue to five-year disease-specific survival (DSS) in univariate and multivariate analyses. Protein expression of CALML5 and LIMA1 were significantly associated with five-year DSS in the OTSCC cohort in univariate analyses (p = 0.016 and p = 0.043, respectively). In multivariate analyses, lymph node metastases, tumor differentiation, and CALML5 were independent prognosticators. The prognostic role of the other selected markers for head and neck cancer patients identified through unbiased approaches could not be validated in our OTSCC cohort. This underlines the need for subsite-specific analyses for head and neck cancer.

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He, Xun Yu, und Zhuan Ma. „The Study on Voltage Control Based on MAS and Grid Technology“. Applied Mechanics and Materials 599-601 (August 2014): 747–50. http://dx.doi.org/10.4028/www.scientific.net/amm.599-601.747.

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In order to build a truly open OpenDSS and enhance the complexity of decision-making DSS for solving the problem of voltage control. a new model was given based on MAS in grid environment. Making use of the intelligence of MAS and adaptive capacity, based on the reasoning mechanisms for task decomposition and resource decision-making grid matching, a new intelligent algorithm based on MAS in order to improve its control effect, and the paper uses the kind of algorithm to coordinated secondary voltage control. The simulation results show the voltage control based on the algorithm have better global best properties and coordinate voltage effectively than routine method.

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Khanna, Pankaj, und P. C. Basak. „An integrated information management system based DSS for problem solving and decision making in open & distance learning institutions of India“. Decision Science Letters 3, Nr. 2 (2014): 209–24. http://dx.doi.org/10.5267/j.dsl.2013.11.002.

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Francik, Sławomir, Adrian Knapczyk, Artur Knapczyk und Renata Francik. „Decision Support System for the Production of Miscanthus and Willow Briquettes“. Energies 13, Nr. 6 (15.03.2020): 1364. http://dx.doi.org/10.3390/en13061364.

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The biomass is regarded as a part of renewable energy sources (RES), which can satisfy energy demands. Biomass obtained from plantations is characterized by low bulk density, which increases transport and storage costs. Briquetting is a technology that relies on pressing biomass with the aim of obtaining a denser product (briquettes). In the production of solid biofuels, the technological as well as material variables significantly influence the densification process, and as a result influence the end quality of briquette. This process progresses differently for different materials. Therefore, the optimal selection of process’ parameters is very difficult. It is necessary to use a decision support tool—decision support system (DSS). The purpose of the work was to develop a decision support system that would indicate the optimal parameters for conducting the process of producing Miscanthus and willow briquettes (pre-comminution, milling and briquetting), briquette parameters (durability and specific density) and total energy consumption based on process simulation. Artificial neural networks (ANNs) were used to describe the relationship between individual parameters of the briquette production process. DSS has the form of a web application and is opened from a web browser (it is possible to open it on various types of devices). The modular design allows the modification and expansion the application in the future.

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Wong, Eugene Hung Chih, Yew Toong Liew, Siow Ping Loong und Narayanan Prepageran. „Five-year Survival Data on the Role of Endoscopic Endonasal Nasopharyngectomy in Advanced Recurrent rT3 and rT4 Nasopharyngeal Carcinoma“. Annals of Otology, Rhinology & Laryngology 129, Nr. 3 (08.11.2019): 287–93. http://dx.doi.org/10.1177/0003489419887410.

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Aim: Endoscopic endonasal nasopharyngectomy (EEN) for recurrent nasopharyngeal carcinoma (rNPC) is being increasingly used due to the added high magnification, reduced morbidities associated with open procedures and good survival outcomes. Most studies looked at usage of EEN in patients with lower recurrent staging (rT1 and rT2) although more and more surgeons are studying the outcome of EEN in advanced rNPC (rT3 and rT4). The aims of this study were to report the long-term 5-year survival outcome of EEN performed in patients with advanced rNPC, and to determine any prognostic factors for patients’ survival. Methods: All patients who underwent EEN for advanced rNPC between January 2003 and December 2015 inclusive were analyzed. All surgeries were performed in University Malaya Medical Centre in Kuala Lumpur and Queen Elizabeth Hospital in Sabah. We reported the 5-year overall survival (OS), disease-free survival (DFS) and disease-specific survival (DSS) and any related complications and significant prognostic factors. Results: Twelve patients with rNPC (2 rT3 and 10 rT4) were followed-up over a mean duration of 44.8 months (range, 40-440 weeks). The 5-year OS was 50.0% (mean 44.75 months), DFS was 25.0% (mean 35.25 months) and the DSS was 58.3% (mean 43.33 months). No severe operative complications were encountered and no independent prognostic factors for survival outcome were identified. Conclusion: This is the first report in English that exclusively described the long-term 5-year survival data in patients with both rT3 and rT4 recurrent NPC after EEN. The data suggest that EEN is a feasible treatment to improve survival with minimal morbidities in patients with rT3 and rT4 recurrent NPC. However, more studies with larger patient size is recommended.

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Sudharsan, D., J. Adinarayana, A. K. Tripathy, S. Ninomiya, M. Hirafuji, T. Kiura, U. B. Desai, S. N. Merchant, D. Raji Reddy und G. Sreenivas. „GeoSense: A Multimode Information and Communication System“. ISRN Sensor Networks 2012 (31.05.2012): 1–13. http://dx.doi.org/10.5402/2012/215103.

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Recent technological developments allowed to envision the low-power (solar power) and low-cost (open hardware) sensor devices (Agrisens/FieldServer/Flux Tower/FieldTwitter) with multimode (ZigBee/WiFi/3G/WebGIS) information and communication technologies (ICTs), a model in which is christened as GeoSense. Integrating these multimode and multi-level communication systems with distributed ambient sensory network location-based service (LBS) is a challenging task, which could be a potential technology for monitoring various natural phenomena. This integrated model is introduced to provide and assist the rural stakeholders with real-time decision support system (DSS) with dynamic information and modeling services for precision agriculture through GeoSense cloud service. This GeoSense research has been experimented in semiarid tropics in India under Indo-Japan initiative on multi-disciplinary ICT program.

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Hader, WJ. „The low adherence and disability outcomes of disease-modifying drugs in Multiple Sclerosis in Saskatchewan, a cohort study, 1997-2014“. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 42, S1 (Mai 2015): S32. http://dx.doi.org/10.1017/cjn.2015.152.

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Background: The beneficial effects of the injected disease-modifying drugs (DMDs) in relapsing-remitting Multiple Sclerosis have been previously reported. However the results related to disability outcomes and the reduction of disease progression in the pivotal trials and few longer studies are variable and inconclusive. Objectives: To determine the utilization and the disability outcomes of the DMDs on relapsing-remitting Multiple Sclerosis over fifteen years. Methods: A prospective open-label cohort of 262 clinical definite patients, 78 men and 184 women, with two attacks in the past two years and a disability level DSS≤5.5 were enrolled consecutively from December 1997 to November 1999. A descriptive analysis of the cohort and individual drugs outcomes were performed. The results were compared to natural history studies of Multiple Sclerosis as controls. Results: At 15 years, one-seventh, 38/262 (14.5%) remain on the initial prescription, Betaseron, 15/131 (11.5%), Copaxone, 16/102 (15.5%) and Rebif 7/28 (25%), Avonex 0/1. 223(63.6%) had discontinued at a mean duration of 5.5(SD=4.7) years. 95/262 (36.4%) remain on a drug after switches. The DSS levels of the individual DMDs were analyzed. Conclusion: One-seventh of participants remained on their first prescription. Because of low adherence, the impact of DMDs on disease progression in the longer term cannot be verified.

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Li, Chun-Yang, Xiu-Lan Chen, Xuan Shao, Tian-Di Wei, Peng Wang, Bin-Bin Xie, Qi-Long Qin et al. „Mechanistic Insight into TrimethylamineN-Oxide Recognition by the Marine Bacterium Ruegeria pomeroyi DSS-3“. Journal of Bacteriology 197, Nr. 21 (17.08.2015): 3378–87. http://dx.doi.org/10.1128/jb.00542-15.

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ABSTRACTTrimethylamineN-oxide (TMAO) is an important nitrogen source for marine bacteria. TMAO can also be metabolized by marine bacteria into volatile methylated amines, the precursors of the greenhouse gas nitrous oxide. However, it was not known how TMAO is recognized and imported by bacteria.Ruegeria pomeroyiDSS-3, a marineRoseobacter, has an ATP-binding cassette transporter, TmoXWV, specific for TMAO. TmoX is the substrate-binding protein of the TmoXWV transporter. In this study, the substrate specificity of TmoX ofR. pomeroyiDSS-3 was characterized. We further determined the structure of the TmoX/TMAO complex and studied the TMAO-binding mechanism of TmoX by biochemical, structural, and mutational analyses. A Ca2+ion chelated by an extended loop in TmoX was shown to be important for maintaining the stability of TmoX. Molecular dynamics simulations indicate that TmoX can alternate between “open” and “closed” states for binding TMAO. In the substrate-binding pocket, four tryptophan residues interact with the quaternary amine of TMAO by cation-π interactions, and Glu131 forms a hydrogen bond with the polar oxygen atom of TMAO. The π-π stacking interactions between the side chains of Phe and Trp are also essential for TMAO binding. Sequence analysis suggests that the TMAO-binding mechanism of TmoX may have universal significance in marine bacteria, especially in the marineRoseobacterclade. This study sheds light on how marine microorganisms utilize TMAO.IMPORTANCETrimethylamineN-oxide (TMAO) is an important nitrogen source for marine bacteria. The products of TMAO metabolized by bacteria are part of the precursors of the greenhouse gas nitrous oxide. It is unclear how TMAO is recognized and imported by bacteria. TmoX is the substrate-binding protein of a TMAO-specific transporter. Here, the substrate specificity of TmoX ofRuegeria pomeroyiDSS-3 was characterized. The TMAO-binding mechanism of TmoX was studied by biochemical, structural, and mutational analyses. Moreover, our results suggest that the TMAO-binding mechanism may have universal significance in marine bacteria. This study sheds light on how marine microorganisms utilize TMAO and should lead to a better understanding of marine nitrogen cycling.

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