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Thematische Bibliographien / Novel actinomycetes

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Auswahl der wissenschaftlichen Literatur zum Thema „Novel actinomycetes“

Autor: Grafiati

Veröffentlicht am 18. Mai 2024

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Zeitschriftenartikel zum Thema "Novel actinomycetes"

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Jagannathan, Sveta V., Erika M. Manemann, Sarah E. Rowe, Maiya C. Callender und William Soto. „Marine Actinomycetes, New Sources of Biotechnological Products“. Marine Drugs 19, Nr. 7 (25.06.2021): 365. http://dx.doi.org/10.3390/md19070365.

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The Actinomycetales order is one of great genetic and functional diversity, including diversity in the production of secondary metabolites which have uses in medical, environmental rehabilitation, and industrial applications. Secondary metabolites produced by actinomycete species are an abundant source of antibiotics, antitumor agents, anthelmintics, and antifungals. These actinomycete-derived medicines are in circulation as current treatments, but actinomycetes are also being explored as potential sources of new compounds to combat multidrug resistance in pathogenic bacteria. Actinomycetes as a potential to solve environmental concerns is another area of recent investigation, particularly their utility in the bioremediation of pesticides, toxic metals, radioactive wastes, and biofouling. Other applications include biofuels, detergents, and food preservatives/additives. Exploring other unique properties of actinomycetes will allow for a deeper understanding of this interesting taxonomic group. Combined with genetic engineering, microbial experimental evolution, and other enhancement techniques, it is reasonable to assume that the use of marine actinomycetes will continue to increase. Novel products will begin to be developed for diverse applied research purposes, including zymology and enology. This paper outlines the current knowledge of actinomycete usage in applied research, focusing on marine isolates and providing direction for future research.

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Wang, Dong-sheng, Hai-ke Ren, E. Erihemu und Zhi-yi Zheng. „Isolation, identification and antagonistic activity evaluation of actinomycetes in barks of nine trees“. Archives of Biological Sciences 69, Nr. 2 (2017): 345–51. http://dx.doi.org/10.2298/abs160429109w.

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Actinomycetes are important producers of novel bioactive compounds. New sources need to be explored for isolating previously unknown bioactive compound-producing actinomycetes. Here we evaluated the potential of bark as a natural source of novel bioactive actinomycete species. Bark samples were collected from nine tree species at different elevations (1600-3400 ma.s.l.) on Qin Mountain, Shaanxi Province, China. Actinomycetes were cultivated, enumerated and isolated using serial dilution and spread-plate techniques. The antimicrobial activity of actinomycete isolates was analyzed using an agar block method against 15 typical bacterial and fungal species and plant pathogens. The dominant isolates were identified by 16S rRNA-based sequence analysis. Results showed that actinomycete counts in bark samples of Quercus liaotungensis Koidz. was the highest among all trees species tested. The numbers of actinomycete species in bark samples were highest in Q. aliena var. acutiserrata and Spiraea alpina Pall. Antagonistic activity wasdetected in approximately 54% of the actinomycete isolates. Of these, 20 isolates (25%) showed broad-spectrum antagonistic activity against ?5 of the microorganisms tested. In conclusion, the bark on coniferous and broadleaf trees possesses a high diversity of actinomycetes and serves as a natural source of bioactive compound-producing actinomycetes.

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Solecka, Jolanta, Joanna Zajko, Magdalena Postek und Aleksandra Rajnisz. „Biologically active secondary metabolites from Actinomycetes“. Open Life Sciences 7, Nr. 3 (01.06.2012): 373–90. http://dx.doi.org/10.2478/s11535-012-0036-1.

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AbstractSecondary metabolites obtained from Actinomycetales provide a potential source of many novel compounds with antibacterial, antitumour, antifungal, antiviral, antiparasitic and other properties. The majority of these compounds are widely used as medicines for combating multidrug-resistant Gram-positive and Gram-negative bacterial strains. Members of the genus Streptomyces are profile producers of previously-known secondary metabolites. Actinomycetes have been isolated from terrestrial soils, from the rhizospheres of plant roots, and recently from marine sediments. This review demonstrates the diversity of secondary metabolites produced by actinomycete strains with respect to their chemical structure, biological activity and origin. On the basis of this diversity, this review concludes that the discovery of new bioactive compounds will continue to pose a great challenge for scientists.

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Subramani und Sipkema. „Marine Rare Actinomycetes: A Promising Source of Structurally Diverse and Unique Novel Natural Products“. Marine Drugs 17, Nr. 5 (26.04.2019): 249. http://dx.doi.org/10.3390/md17050249.

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Rare actinomycetes are prolific in the marine environment; however, knowledge about their diversity, distribution and biochemistry is limited. Marine rare actinomycetes represent a rather untapped source of chemically diverse secondary metabolites and novel bioactive compounds. In this review, we aim to summarize the present knowledge on the isolation, diversity, distribution and natural product discovery of marine rare actinomycetes reported from mid-2013 to 2017. A total of 97 new species, representing 9 novel genera and belonging to 27 families of marine rare actinomycetes have been reported, with the highest numbers of novel isolates from the families Pseudonocardiaceae, Demequinaceae, Micromonosporaceae and Nocardioidaceae. Additionally, this study reviewed 167 new bioactive compounds produced by 58 different rare actinomycete species representing 24 genera. Most of the compounds produced by the marine rare actinomycetes present antibacterial, antifungal, antiparasitic, anticancer or antimalarial activities. The highest numbers of natural products were derived from the genera Nocardiopsis, Micromonospora, Salinispora and Pseudonocardia. Members of the genus Micromonospora were revealed to be the richest source of chemically diverse and unique bioactive natural products.

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Peraud, Olivier, Jason S. Biggs, Ronald W. Hughen, Alan R. Light, Gisela P. Concepcion, Baldomero M. Olivera und Eric W. Schmidt. „Microhabitats within Venomous Cone Snails Contain Diverse Actinobacteria“. Applied and Environmental Microbiology 75, Nr. 21 (11.09.2009): 6820–26. http://dx.doi.org/10.1128/aem.01238-09.

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ABSTRACT Actinomycetes can be symbionts in diverse organisms, including both plants and animals. Some actinomycetes benefit their host by producing small molecule secondary metabolites; the resulting symbioses are often developmentally complex. Actinomycetes associated with three cone snails were studied. Cone snails are venomous tropical marine gastropods which have been extensively examined because of their production of peptide-based neurological toxins, but no microbiological studies have been reported on these organisms. A microhabitat approach was used in which dissected tissue from each snail was treated as an individual sample in order to explore bacteria in the tissues separately. Our results revealed a diverse, novel, and highly culturable cone snail-associated actinomycete community, with some isolates showing promising bioactivity in a neurological assay. This suggests that cone snails may represent an underexplored reservoir of novel actinomycetes of potential interest for drug discovery.

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Saito, Shun, und Midori A. Arai. „Methodology for awakening the potential secondary metabolic capacity in actinomycetes“. Beilstein Journal of Organic Chemistry 20 (10.04.2024): 753–66. http://dx.doi.org/10.3762/bjoc.20.69.

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Secondary metabolites produced by actinomycete strains undoubtedly have great potential for use in applied research areas such as drug discovery. However, it is becoming difficult to obtain novel compounds because of repeated isolation around the world. Therefore, a new strategy for discovering novel secondary metabolites is needed. Many researchers believe that actinomycetes have as yet unanalyzed secondary metabolic activities, and the associated undiscovered secondary metabolite biosynthesis genes are called “silent” genes. This review outlines several approaches to further activate the metabolic potential of actinomycetes.

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Shah, Aabid Manzoor, Shahid Rasool, Aasif Majeed, Saleem Mushtaq, Mudasir Hafiz Khan, Aehtesham Hussain, Aiyatullah Shah und Qazi Parvaiz Hassan. „Reappraisal of actinomycetes for novel bioactive metabolites“. Annals of Phytomedicine: An International Journal VI, Nr. I (30.06.2017): 13–19. http://dx.doi.org/10.21276/ap.2017.6.1.3.

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Handayani, Ira, Hamada Saad, Shanti Ratnakomala, Puspita Lisdiyanti, Wien Kusharyoto, Janina Krause, Andreas Kulik et al. „Mining Indonesian Microbial Biodiversity for Novel Natural Compounds by a Combined Genome Mining and Molecular Networking Approach“. Marine Drugs 19, Nr. 6 (28.05.2021): 316. http://dx.doi.org/10.3390/md19060316.

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Indonesia is one of the most biodiverse countries in the world and a promising resource for novel natural compound producers. Actinomycetes produce about two thirds of all clinically used antibiotics. Thus, exploiting Indonesia’s microbial diversity for actinomycetes may lead to the discovery of novel antibiotics. A total of 422 actinomycete strains were isolated from three different unique areas in Indonesia and tested for their antimicrobial activity. Nine potent bioactive strains were prioritized for further drug screening approaches. The nine strains were cultivated in different solid and liquid media, and a combination of genome mining analysis and mass spectrometry (MS)-based molecular networking was employed to identify potential novel compounds. By correlating secondary metabolite gene cluster data with MS-based molecular networking results, we identified several gene cluster-encoded biosynthetic products from the nine strains, including naphthyridinomycin, amicetin, echinomycin, tirandamycin, antimycin, and desferrioxamine B. Moreover, 16 putative ion clusters and numerous gene clusters were detected that could not be associated with any known compound, indicating that the strains can produce novel secondary metabolites. Our results demonstrate that sampling of actinomycetes from unique and biodiversity-rich habitats, such as Indonesia, along with a combination of gene cluster networking and molecular networking approaches, accelerates natural product identification.

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Tarasova, Ekaterina V., Natalia A. Luchnikova, Victoria V. Grishko und Irina B. Ivshina. „Actinomycetes as Producers of Biologically Active Terpenoids: Current Trends and Patents“. Pharmaceuticals 16, Nr. 6 (12.06.2023): 872. http://dx.doi.org/10.3390/ph16060872.

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Terpenes and their derivatives (terpenoids and meroterpenoids, in particular) constitute the largest class of natural compounds, which have valuable biological activities and are promising therapeutic agents. The present review assesses the biosynthetic capabilities of actinomycetes to produce various terpene derivatives; reports the main methodological approaches to searching for new terpenes and their derivatives; identifies the most active terpene producers among actinomycetes; and describes the chemical diversity and biological properties of the obtained compounds. Among terpene derivatives isolated from actinomycetes, compounds with pronounced antifungal, antiviral, antitumor, anti-inflammatory, and other effects were determined. Actinomycete-produced terpenoids and meroterpenoids with high antimicrobial activity are of interest as a source of novel antibiotics effective against drug-resistant pathogenic bacteria. Most of the discovered terpene derivatives are produced by the genus Streptomyces; however, recent publications have reported terpene biosynthesis by members of the genera Actinomadura, Allokutzneria, Amycolatopsis, Kitasatosporia, Micromonospora, Nocardiopsis, Salinispora, Verrucosispora, etc. It should be noted that the use of genetically modified actinomycetes is an effective tool for studying and regulating terpenes, as well as increasing productivity of terpene biosynthesis in comparison with native producers. The review includes research articles on terpene biosynthesis by Actinomycetes between 2000 and 2022, and a patent analysis in this area shows current trends and actual research directions in this field.

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C. P., Kulkarni, und Maurya C. B. „Characterization of the Cellulase Enzyme Produced by Actinomycetes Isolated from the Mangrove Coastal Areas“. Biosciences, Biotechnology Research Asia 14, Nr. 2 (25.06.2017): 685–90. http://dx.doi.org/10.13005/bbra/2495.

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ABSTRACT: Cellulase enzyme plays an important role in converting cellulosic biomass in high value products and therefore finds various applications in a number of industries such as pulp and paper, textile, laundry, biofuel production, food and feed industry, brewing and agriculture. Although there are various sources available for obtaining enzymes of industrial applications such as bacteria, fungi, actinomycetes, microalgae, animals and plants; microorganisms represent the most common source of enzymes because of their broad biochemical diversity, feasibility of mass culture and ease of genetic manipulation. Among the microorganisms, actinomycetes are increasingly becoming an important resource for the production of therapeutic molecules and industrially important enzymes. Considering this, the present investigation was undertaken to isolate a novel actinomycete strain from a sea sediment sample and explore its ability to produce the enzyme cellulase. After morphological and biochemical studies, this actinomycete strain was further characterized using its 16S rRNA gene sequence and a phylogenetic tree was constructed. The activity and stability of the extracted enzyme from this actinomycete was analyzed. Finally, the applications of this extracted enzyme were studied.

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Dissertationen zum Thema "Novel actinomycetes"

1

Nakouti, Ismini. „Iron binding compounds produced by novel Actinomycetes“. Thesis, Liverpool John Moores University, 2008. http://researchonline.ljmu.ac.uk/5868/.

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Yallop, C. „The isolation and characterisation of novel acidophilic thermoactinomyces isolates“. Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240951.

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Pimentel, Elardo Sheila Marie. „Novel anti-infective secondary metabolites and biosynthetic gene clusters from actinomycetes associated with marine sponges“. Doctoral thesis, kostenfrei, 2008. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-40463.

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Marine sponges (Porifera) harbor diverse microbial communities within their mesohyl, among them representatives of the phylum Actinobacteria, commonly known as actinomycetes. Actinomycetes are prolific producers of pharmacologically important compounds and are responsible for producing the majority of antibiotics. The main aim of this Ph.D. study was to investigate the metabolic potential of the sponge-associated actinomycetes to produce novel anti-infective agents. The first aim was to cultivate actinomycetes derived from different marine sponges. 16S rDNA sequencing revealed that the strains belonged to diverse actinomycete genera such as Gordonia, Isoptericola, Micromonospora, Nocardiopsis, Saccharopolyspora and Streptomyces. Phylogenetic analyses and polyphasic characterization further revealed that two of these strains represent new species, namely Saccharopolyspora cebuensis strain SPE 10-1T (Pimentel-Elardo et al. 2008a) and Streptomyces axinellae strain Pol001T (Pimentel-Elardo et al. 2008b). Furthermore, secondary metabolite production of the actinomycete strains was investigated. The metabolites were isolated using a bioassay-guided purification scheme followed by structure elucidation using spectroscopic methods and subjected to an elaborate anti-infective screening panel. Several interesting compounds were isolated namely, the novel polyketides cebulactam A1 and A2 (Pimentel-Elardo et al. 2008c), a family of tetromycin compounds including novel derivatives, cyclodepsipeptide valinomycin, indolocarbazole staurosporine, diketopiperazine cycloisoleucylprolyl and butenolide. These compounds exhibited significant anti-parasitic as well as protease inhibitory activities. The third aim of this Ph.D. study was to identify biosynthetic gene clusters encoding for nonribosomal peptide synthetases (NRPS) and polyketide synthases (PKS) present in the actinomycete strains. Genomic library construction and sequencing revealed insights into the metabolic potential and biosynthetic pathways of selected strains. An interesting NRPS system detected in Streptomyces sp. strain Aer003 was found to be widely distributed in several sponge species, in an ascidian and in seawater and is postulated to encode for a large peptide molecule. Sequencing of the PKS gene cluster of Saccharopolyspora cebuensis strain SPE 10-1T allowed the prediction of the cebulactam biosynthetic pathway which utilizes 3-amino-5-hydroxybenzoic acid as the starter unit followed by successive condensation steps involving methylmalonyl extender units and auxiliary domains responsible for the polyketide assembly. In conclusion, this Ph.D. study has shown that diverse actinomycete genera are associated with marine sponges. The strains, two of them novel species, produced diverse chemical structures with interesting anti-infective properties. Lastly, the presence of biosynthetic gene clusters identified in this study substantiates the biosynthetic potential of actinomycetes to produce exploitable natural products and hopefully provides a sustainable supply of anti-infective compounds
Zahlreiche marine Schwämme (Phylum: Porifera) beherbergen eine phylogenetisch diverse mikrobielle Gemeinschaft in der Mesohyl-Matrix, darunter auch viele Vertreter des bakteriellen Phylums Actinobacteria, die umgangssprachlich als Actinomyceten bekannt sind. Actinomyceten sind wichtige Produzenten vieler Antibiotika und von weiteren pharmazeutisch relevanten Substanzen. Das Hauptziel dieser Promotionsarbeit war die Untersuchung des Potentials Schwamm-assoziierter Actinomyceten zur Produktion neuer Infektions-hemmender Substanzen. Ein erstes Ziel dieser Doktorarbeit war die Kultivierung von Actinomyceten aus verschiedenen marinen Schwammarten. Die Sequenzierung der respektiven 16S rRNA Gene zeigte eine phylogenetische Zugehörigkeit der Isolate zu verschiedenen Actinomyceten-Familien, wie Gordonia, Isoptericola, Micromonospora, Nocardiopsis, Saccharopolyspora und Streptomyces. Durch phylogenetische Analysen und umfangreiche taxonomische Charakterisierungen konnten zwei neue Actinomyceten-Arten, Saccharopolyspora cebuensis strain SPE 10-1T (Pimentel-Elardo et al. 2008a) und Streptomyces axinellae strain Pol001T (Pimentel-Elardo et al. 2008b) beschrieben werden. Des Weiteren sollten die Actinomyceten-Isolate auf die Produktion von Sekundär-Metaboliten hin untersucht werden. Die Substanzen wurden „bioassay-guided“ aufgereinigt und isoliert sowie deren Struktur mittels spektroskopischer Methoden aufgeklärt. Anschließend wurden die Substanzen ausführlichen Screening-Methoden unterzogen, um sie auf anti-infektive Wirkungen hin zu untersuchen. Zahlreiche interessante Verbindungen konnten so isoliert werden, u. a. die neuen Polyketide Cebulactam A1 und A2 (Pimentel-Elardo et al. 2008c); eine Familie von Tetromycin-Substanzen inklusive neuartiger Derivative; das Cyclodepsipeptid Valinomycin, Indolocarbazole Staurosporine, Diketopiperazine Cycloisoleucylprolyl und Butenolide. Die Verbindungen zeigten signifikante anti-parasitische und Protease-hemmende Aktivitäten. Das dritte Ziel dieser Arbeit war es, die für nicht-ribosomale Peptidsynthetasen (NRPS) und Polyketidsynthasen (PKS) kodierenden, biosynthetischen Gen-Cluster in den Actinomyceten-Isolaten zu identifizieren. Die Konstruktion von Genbanken sowie die Sequenzierung ausgewählter Cosmidklone lieferte erste Einblicke in das Stoffwechsel- und Biosynthesepotential ausgewählter Isolate. Beispielsweise konnte ein interessantes NRPS-System in Streptomyces sp. Stamm Aer003 identifiziert werden, welches in verschiedenen Schwammarten, einer Ascidienart sowie im Meerwasser gefunden wurde. Die Sequenzierung eines PKS-Genclusters aus Saccharopolyspora cebuensis strain SPE 10-1T ermöglicht die Voraussage des Cebulactam-Biosynthesewegs in dem 3-Amino-5-Hydroxybenzoesäure als Ausgangsprodukt dient, welches durch sukzessive Kondensationsschritte sowie Verlängerungen durch Methylmalonyl- und Zusatzdomänen zum endgültigen Polyketid führen. Zusammenfassend konnte in dieser Promotionsarbeit gezeigt werden, dass marine Schwämme mit diversen Vertretern aus verschiedenen Familien der Actinomyceten assoziiert sind. Die Bakterienisolate, von denen zwei neue Arten repräsentieren, produzierten mehrere chemische Substanzen mit interessanten anti-infektiven Eigenschaften. Des Weiteren konnte mit dieser Arbeit durch die Identifizierung von Biosynthese-Genclustern das Potential von Actinomyceten zur Produktion verwertbarer bioaktiver Substanzen bekräftigt und somit ein Beitrag zur Entdeckung neuer anti-infektiver Substanzen erbracht werden

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Hilberath, Thomas [Verfasser], Vlada B. [Gutachter] Urlacher und Martina [Gutachter] Pohl. „Identification and characterization of novel cytochromes P450 from actinomycetes / Thomas Hilberath ; Gutachter: Vlada B. Urlacher, Martina Pohl“. Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2021. http://d-nb.info/1235755843/34.

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Ray, Pushpanjali. „Search for novel actinomycetes from soil as potential biocontrol agent against fungal root pathogens of phaseolus vulgaris (L.) vigna radiata(L.)“. Thesis, University of North Bengal, 2017. http://ir.nbu.ac.in/hdl.handle.net/123456789/2575.

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Cheng, Cheng [Verfasser], und Ute [Gutachter] Hentschel. „Metabolomics and dereplication-based isolation of novel bioactive natural products from marine sponge-associated actinomycetes / Cheng Cheng ; Gutachter: Ute Hentschel“. Würzburg : Universität Würzburg, 2016. http://d-nb.info/1137467703/34.

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Carlsohn, Marc René [Verfasser], Thomas [Akademischer Betreuer] Munder, Hans Peter [Akademischer Betreuer] Saluz und Michael [Akademischer Betreuer] Goodfellow. „Isolation and characterization of mine-dwelling actinomycetes as potential producers of novel bioactive secondary metabolites / Marc René Carlsohn. Gutachter: Thomas Munder ; Hans Peter Saluz ; Michael Goodfellow“. Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2011. http://d-nb.info/1017078912/34.

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Wong, Hiu-ling Beatrice. „Characterization of a novel actinomyces species discovered in Hong Kong“. Click to view the E-thesis via HKUTO, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31971313.

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黃曉靈 und Hiu-ling Beatrice Wong. „Characterization of a novel actinomyces species discovered in Hong Kong“. Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31971313.

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PAN, CHENGQIAN. „Discovery of Novel Bioactive Compounds from a Rare Actinomycete Amycolatopsis sp. 26-4“. Kyoto University, 2020. http://hdl.handle.net/2433/259019.

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Buchteile zum Thema "Novel actinomycetes"

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Yaradoddi, Jayachandra S., Merja H. Kontro, Nagaraj R. Banapurmath, Sharanabasava V. Ganachari und M. K. Umesh. „Identification of Novel Actinomycetes“. In Actinobacteria, 143–57. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3353-9_8.

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Wang, Kaimei, Shaoyong Ke, Wei Fang, Zhaoyuan Wu und Yani Zhang. „Novel Agroactive Secondary Metabolites from Actinomycetes in the Past Two Decades with Focus on Screening Strategies and Discovery“. In Natural Products from Actinomycetes, 199–221. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-6132-7_9.

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Boufridi, Asmaa, Candice M. Brinkmann, Chandra Risdian, Joachim Wink und D. İpek Kurtböke. „Sponge Symbiotic Actinomycetes as Sources of Novel Bioactive Compounds Atlantic and Pacific Ocean Examples“. In Actinomycetes in Marine and Extreme Environments, 1–26. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9780429293948-1.

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Piepersberg, Wolfgang. „Glycosylation of Antibiotics and Other Agents from Actinomycetes“. In Novel Frontiers in the Production of Compounds for Biomedical Use, 161–68. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/0-306-46885-9_10.

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Salas, JoseA, Gloria Blanco, Alfredo F. Braña, Ernestina Fernandez, Ma Jose Fernandez, Jose Garcia Bernrdo, Ana Gonzalez et al. „Towards the Generation of Novel Antitumour Agents from Actinomycetes by Combinational Biosynthesis“. In Novel Frontiers in the Production of Compounds for Biomedical Use, 383–99. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/0-306-46885-9_23.

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Kurtböke, D. İpek, John R. J. French, R. Andrew Hayes und Ronald J. Quinn. „Eco-Taxonomic Insights into Actinomycete Symbionts of Termites for Discovery of Novel Bioactive Compounds“. In Biotechnological Applications of Biodiversity, 111–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/10_2014_270.

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O'DONNELL, ANTHONY G. „Recognition of Novel Actinomycetes“. In Actinomycetes in Biotechnology, 69–88. Elsevier, 1988. http://dx.doi.org/10.1016/b978-0-12-289673-6.50008-7.

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Horan, Ann C. „Aerobic Actinomycetes: A Continuing Source of Novel Natural Products“. In Discovery of Novel Natural Products with Therapeutic Potential, 3–30. Elsevier, 1994. http://dx.doi.org/10.1016/b978-0-7506-9003-4.50007-1.

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Singh, Shalini, und Pushkar Singh Rawat. „Biodegradation of Plastic“. In Handbook of Research on Environmental and Human Health Impacts of Plastic Pollution, 435–61. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-5225-9452-9.ch022.

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The use of plastics is increasing gradually, and its degradation is becoming a great threat for society. This chapter raises a question in front of us: Ultimately, how can we balance our needs and safety? Therefore, a term biodegradation is frequently used to explain the ability of microorganism to degrade the organic substance. The chapter would deliver the importance of biodegradation of plastic products, which is a rapidly growing field and offers a new dimension solution with novel properties in waste management areas. Microorganisms like bacteria, fungi, and actinomycetes have developed a special strategy in order to use such materials as energy and carbon source. Biodegradation is the most economic, eco-friendly, and acceptable method. But the detailed characterization of efficient plastic-degrading microbes and microbial enzymes still needs to be carried out. The chapter would also provide a better understanding related to the biodegradation of plastic products that enhances the horizon of knowledge.

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N. Moholkar, Disha, Darshana V. Havaldar, Rachana S. Potadar und Kiran D. Pawar. „Optimization of Biogenic Synthesis of Colloidal Metal Nanoparticles“. In Colloids - Types, Preparation and Applications [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94853.

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Nanotechnology which deals with the synthesis and characterization of dispersed or solid particles in nano-metric range has emerged out to be a novel approach due to its ample applications in biomedical fields. The advancements in the field of nanotechnology and substantial evidences in biomedical applications have led the researchers to explore safe, ecofriendly, rapid and sustainable approaches for the synthesis of colloidal metal nanoparticles. This chapter illustrates superiority of biogenic route of synthesis of nanoparticles over the different approaches such as chemical and physical methods. In biogenic route, plants and microorganisms like algae, fungi, yeast, actinomycetes etc. act as “bio-factories” which reduce the metal precursors and play a crucial role in the synthesis of nanoparticles with distinct morphologies. Thus, the need of hazardous chemicals is eliminated and a safer and greener approach of nanoparticles synthesis can be adopted. This chapter also outlines the effect of optimization of different parameters mainly pH, temperature, time and concentration of metal ions on the nanoparticle synthesis. It is evident that the optimization of various parameters can yield nanoparticles with desired properties suitable for respective biomedical applications.

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Konferenzberichte zum Thema "Novel actinomycetes"

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Hostler, Jordanna, Robert Paris und John Sherner. „Rapidly Progressive Respiratory Failure In A Deployed Servicemember: A Novel Presentation Of Actinomyces Empyema“. In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5699.

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