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Thematische Bibliographien / North Carolina Immigration Association / Dissertationen

Dissertationen zum Thema „North Carolina Immigration Association“

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Autor: Grafiati

Veröffentlicht am 27. Juli 2024

Zuletzt aktualisiert am 29. Juli 2024

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1

Liu, Youfang. „Analytical tools for population-based association studies“. NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-08182008-161113/.

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Disease gene fine mapping is an important task in human genetic research. Association analysis is becoming a primary approach for localizing disease loci, especially when abundant SNPs are available due to the well improved genotyping technology during the last decades. Despite the rapid improvement of detection ability, there are many limitations of association strategy. In this dissertation, we focused on three different topics including haplotype similarity based test, association test incorporating genotyping error and simulation tool for large data set. 1) Previous haplotype similarity based tests donât have the ability to incorporate covariates in the test. In chapter 2, we proposed a new association method based on haplotype similarity that incorporates covariates and utilizes maximum amount of data information. We found that our method gives power improvement when neither LD nor allele frequency is too low and is comparable under other scenarios. 2) In chapter 3, we proposed a new strategy that incorporates the genotyping uncertainty to assess the association between traits and SNPs. Extensive simulation studies for case-control designs demonstrated that intensity information based association test can reduce the impact induced by genotyping error. 3) In chapter 4, we described simulation software, SimuGeno, which is used to simulate large scale genomic data for case-control association studies.

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2

Monks, Stephanie A. „Family-based methods which rely on association for the mapping of genes in human populations“. Raleigh, NC : North Carolina State University, 1999. http://www.lib.ncsu.edu/etd/public/etd-05391449951331/etd.pdf.

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3

Morris, Richard Wayne. „Likelihood ratio tests for association with multiple disease susceptibility alleles, genotyping errors, or missing parental data“. NCSU, 2003. http://www.lib.ncsu.edu/theses/available/etd-06232003-122033/.

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Multiple disease susceptibility alleles, genotype errors, or missing genotype data can create problems when testing for association between alleles or genotypes at a genetic marker and a dichotomous phenotype. I used likelihood methods to study the impact of each of these factors on detecting association. In the presence of multiple disease susceptibility alleles, I found that power of the likelihood ratio test (LRT) declines less when based on haplotypes made up of tightly linked single nucleotide polymorphisms (SNPs) than when based on individual SNPs. The result suggests that statistical methods based on haplotypes may be useful to identify and locate complex disease genes. Genotype errors can lead to excess type I error in nuclear family (case-parents) studies when errors resulting in Mendelian inconsistent families are corrected but other errors remain in the data. I developed a LRT for single SNPs or haplotypes that incorporates nuisance parameters for genotype errors and showed that type I error rate can be controlled at little cost to power. For nuclear family data in which missing parents and additional siblings create a diversity of family structures, I developed a unified approach to computing LRT power for a test of association. Comparison of LRT power with power of a family-based association test showed that LRT has greater power.

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4

Chung, Ren-Hua. „STATISTICAL METHODS FOR FAMILY-BASED ASSOCIATION STUDIES FOR COMPLEX HUMAN DISEASES: SINGLE-LOCUS AND HAPLOTYPE METHODS“. NCSU, 2006. http://www.lib.ncsu.edu/theses/available/etd-11062006-134924/.

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Disease-gene fine-mapping is an important task in human genetics. Linkage and association analyses are the two main approaches for exploring disease susceptibility genes. In Chapter 1, we introduce the development of methods for disease-gene mapping in the past decades and present the rationale behind our new method development. Family-based association analyses have provided powerful tools for disease-gene mapping. The Association in the Presence of Linkage test (APL), a family-based association method, can use nuclear families with multiple affected siblings and infer missing parental genotypes properly in the linkage region. In Chapter 2, we generalized and extended APL so that it can be applied to general nuclear family structures using a bootstrap variance estimator. Unlike the original APL that can handle at most two affected siblings, the new APL can handle up to three affected siblings. We also extended APL from a single-marker test to a multiple-marker haplotype analysis. According to our simulations, the new APL has a correct type I error rate and more power than other family-based association methods such as PDT, FBAT/HBAT, and PDTPHASE in nuclear families with missing parents. The robustness of APL when there are rare alleles or haplotypes and when there is population substructure such that the allele frequencies in the population deviated from the Hardy-Weinberg Equilibrium (HWE) assumption was also examined in Chapter 2. Genes on the X chromosome play a role in many common diseases. Linkage analyses have identified regions on the X chromosome with high linkage peaks for several diseases. Currently there are few family-based association methods available for X-chromosome markers. In order to fill in this gap, we proposed a novel family-based association method, X-APL, in Chapter 3. X-APL is a modification of APL and shares some important properties with APL. X-APL can also perform haplotype analyses, which is the only family-based test of association we are aware of for testing haplotypes for the X-chromosome markers. Our simulation results showed that X-APL has a correct type I error rate and has more power than other family-based association methods for X chromosome such as XS-TDT, XPDT and XMCPDT for single-marker analysis in nuclear families. The robustness of X-APL when there are deviations of genotype frequencies from HWE was also examined in Chapter 3. Linkage and family-based association analyses are often applied simultaneously in the same data in order to maximize use of family data sets. However, it is not intuitively clear under what conditions association and linkage tests performed in the same data set may be correlated. In Chapter 4, we used computer simulations and theoretical statements to estimate the correlation between linkage statistics (affected sib pair maximum LOD scores) and family-based association statistics (PDT and APL) under various hypotheses. Different types of pedigrees were studied: nuclear families with affected sib pairs, extended pedigrees and incomplete pedigrees. Both simulation and theoretical results showed that when there is either no linkage or no association, the linkage and association statistics are not correlated. When there is linkage and association in the data, the two tests have a positive correlation.

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5

Jones, Chester H. „The development of a ministerial support group for the ministers of Truett Baptist Association, North Carolina“. Theological Research Exchange Network (TREN), 1992. http://www.tren.com.

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6

Spragley, Kelvin Lamont. „Exploring congruity of curriculum and instruction policy positions between the North Carolina Association of Educators and its teacher members“. NCSU, 2009. http://www.lib.ncsu.edu/theses/available/etd-12172008-195717/.

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To better understand issues of congruity between the North Carolina Association of Educators (NCAE) and its teacher membership, this study surveyed a sample of NCAEâs membership about issues related to curriculum and instruction. The research reported here utilized a model (exchange theory) that makes a distinction between voluntary membership organizations and non-voluntary membership organizations. The survey sampled 263 NCAE teacher members. Descriptive statistics, ANOVAs, and content analysis addressed three specific questions about congruity of positions taken by NCAE on curriculum and instruction issues and the beliefs of NCAE members. Results suggest NCAE members hold views very congruent with NCAE leadership. The importance of making distinctions between teacher views in non-bargaining states is a major implication of the findings.

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7

Evans, Lester N. „Leading clergy families to address selected issues which impact clergy family life in Macon Baptist Association, Franklin, North Carolina“. Theological Research Exchange Network (TREN), 1996. http://www.tren.com.

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8

Bogardus, Melinda. „The Experiences and Well-Being of Mexican Immigrant Women Living in Traditionally non-Latinx Communities in Western North Carolina“. Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/etd/3707.

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North Carolina has, in recent decades, experienced significant growth in its Latinx, and more particularly Mexican immigrant population. As a traditionally non-Latinx state, or a state without a long-standing, large Latinx population, many communities and healthcare and service providers within North Carolina still lack knowledge, resources, and skills needed to serve and support Latinx immigrant populations well. Guided by interpretive description, this qualitative study on Mexican immigrant women in Western North Carolina sought to gain knowledge and understanding of what it is like for them to live in a traditionally non-Latinx region and how immigration has affected their well-being. Asking about experiences in the context of immigration as a way of learning about well-being was inspired by scholars who have asserted immigration to be an important determinant of health and well-being and significant life experience. Individual interviews with 12 Mexican immigrant women generated five themes: 1) Difference and Disruption, 2) Losing to Gain, 3) Living with Risks and Limitations, 4) From Lost to Found, and 5) Resilience and Adaptation. Together these themes highlight sacrifices and struggles, strengths and resources, and gains and hope that have affected these women’s well-being and paint an overall picture of resilience and adaptation in spite of losses, difficulties, risks, and limitations incurred by immigrating. These findings argue for use of a strengths-based approach when interacting with Mexican immigrant women to improve healthcare and other services and promote their well-being and integration in their NC communities.

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9

Gillespie, Rachel. „CONNECTING SELF-EFFICACY OF DIETARY CHOICES AND THE ASSOCIATION WITH DIETARY INTAKE AMONG RURAL ADOLESCENTS IN NORTH CAROLINA AND KENTUCKY“. UKnowledge, 2017. https://uknowledge.uky.edu/foodsci_etds/54.

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Determining the level of belief one has in themselves, or their self-efficacy, can be a key factor to improve certain dietary patterns and choices in the rural youth population. Sugar sweetened food and beverage consumption continues to rise and fruit and vegetable intake remains a struggle in rural areas; addressing both the food environment and adolescents’ self-efficacy could have a lasting impact on changing the nature of a generation of rural student’s food and beverage choices. This study measured self-efficacy levels of (n=425) adolescents in rural Kentucky and North Carolina using the Youth Impact Questionnaire and dietary intake using the NHANES Dietary Screener. Multiple linear regression analysis found that higher levels of self-efficacy resulted in a statistically significant ability to consume more vegetables. Further associations found that higher levels of self-efficacy resulted in increased fruit consumption, and improved added sugar food and beverage selections. These findings suggest that it could be beneficial to target adolescents’ self-efficacy as a way to modify certain health behaviors in a sparse food environment such as these rural Appalachian areas.

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10

Bryant, Michael Hugh. „A comparative analysis of factors contributing to the biblical worldview among High School students in the American Association of Christian Schools of Georgia, North Carolina, and South Carolina“. Lynchburg, Va. : Liberty University, 2008. http://digitalcommons.liberty.edu.

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11

Connelly, Paige M. „ADOLESCENT FOOD PURCHASING PATTERNS AND THE ASSOCIATION WITH DIETARY INTAKE AND BODY MASS INDEX IN RURAL COMMUNITIES IN KENTUCKY AND NORTH CAROLINA“. UKnowledge, 2017. https://uknowledge.uky.edu/foodsci_etds/55.

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The local food environment plays an important role in the health of adolescents, especially in rural areas. Often, rural areas lack the accessibility and availability of healthy food choices, making a healthy lifestyle difficult to achieve. This study presents a cross-sectional survey of rural adolescents in 8 counties in Kentucky and North Carolina to determine the association between food store choice, body mass index (BMI), and key dietary outcomes. Although BMI had no association with food store choice, those who infrequently shopped at gas stations, convenience stores, and fast food restaurants consumed significantly less added sugar (p < 0.05) than those who shopped at those stores more regularly. Increasing the availability and accessibility of food venues with healthy food options such as supermarkets may decrease added sugar intake among rural adolescents.

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12

Gao, Xiaoyi. „Statistical methods in genetic association studies“. 2006. http://www.lib.ncsu.edu/theses/available/etd-07032006-153645/unrestricted/etd.pdf.

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13

Jin, Weiqing. „Fuzzy classification based on fuzzy association rule mining“. 2004. http://www.lib.ncsu.edu/theses/available/etd-12072004-130619/unrestricted/etd.pdf.

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14

Liu, Wenlei. „Development of linkage and association methods to map disease genes“. 2002. http://www.lib.ncsu.edu/theses/available/etd-07192002-100823/unrestricted/etd.pdf.

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15

Czika, Wendy Ann. „Accounting for within- and between-locus dependencies in marker association tests“. 2003. http://www.lib.ncsu.edu/theses/available/etd-03272003-130649/unrestricted/etd.pdf.

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16

Wilson, Larissa Mary. „Association mapping of major starch biosynthesis genes in Zea mays ssp. mays“. 2002. http://www.lib.ncsu.edu/theses/available/etd-01062003-142901/unrestricted/etd.pdf.

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17

Jelinek, Susan T. „The association of weed species richness and abundance with field margin type in crop fields“. 2004. http://www.lib.ncsu.edu/theses/available/etd-05132004-134323/unrestricted/etd.pdf.

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18

Nolan, Ronnie. „First-generation graduates of Berea College an examination of the association between the barriers to graduation and the motivating factors /“. 2005. http://www.lib.ncsu.edu/theses/available/etd-07262005-114257/unrestricted/etd.pdf.

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19

Katawczik, Melanie Lynn. „Characterization of xanthomonas euvesicatoria, adaptation of bacterial strains carrying alleles of avrBs2 and association with pathogen aggressiveness under field conditions“. 2007. http://www.lib.ncsu.edu/theses/available/etd-03152007-121215/unrestricted/etd.pdf.

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20

Foster, Daniel Russell. „Roles and practices of community college presidents in the governance of the North Carolina community college system“. 2006. http://www.lib.ncsu.edu/theses/available/etd-04182006-103303/unrestricted/etd.pdf.

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Thesis (Ed.D.)--North Carolina State University.
Includes vita. Originally issued in electronic format. UMI number: 3223137. Includes bibliographical references (p. 104-122). Also available via the World Wide Web.

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21

Noble, Aaron P. „Determining the effectiveness of the International Public Management Association for Human Resources certified professional certification program in assisting HR managers in performing the responsibilities of their job“. 2005. http://www.lib.ncsu.edu/theses/available/etd-04292005-135217/unrestricted/etd.pdf.

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