Auswahl der wissenschaftlichen Literatur zum Thema „Non-canonical initiation codon“
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Zeitschriftenartikel zum Thema "Non-canonical initiation codon"
Firth, Andrew E., und Ian Brierley. „Non-canonical translation in RNA viruses“. Journal of General Virology 93, Nr. 7 (01.07.2012): 1385–409. http://dx.doi.org/10.1099/vir.0.042499-0.
Der volle Inhalt der QuellePrasad, Sharanya, Shelley Starck und Nilabh Shastri. „Presentation of cryptic peptides by MHC I molecules is enhanced by inflammatory stimuli. (P5003)“. Journal of Immunology 190, Nr. 1_Supplement (01.05.2013): 110.2. http://dx.doi.org/10.4049/jimmunol.190.supp.110.2.
Der volle Inhalt der QuelleColdwell, Mark J., Ulrike Sack, Joanne L. Cowan, Rachel M. Barrett, Markete Vlasak, Keiley Sivakumaran und Simon J. Morley. „Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon“. Biochemical Journal 448, Nr. 1 (18.10.2012): 1–11. http://dx.doi.org/10.1042/bj20111765.
Der volle Inhalt der QuelleGraça, Rafael, Rafael Fernandes, Ana Catarina Alves, Juliane Menezes, Luísa Romão und Mafalda Bourbon. „Characterization of Two Variants at Met 1 of the Human LDLR Gene Encoding the Same Amino Acid but Causing Different Functional Phenotypes“. Biomedicines 9, Nr. 9 (14.09.2021): 1219. http://dx.doi.org/10.3390/biomedicines9091219.
Der volle Inhalt der QuelleGao, Fei, Maria Wesolowska, Reuven Agami, Koos Rooijers, Fabricio Loayza-Puch, Conor Lawless, Robert N. Lightowlers und Zofia M. A. Chrzanowska-Lightowlers. „Using mitoribosomal profiling to investigate human mitochondrial translation“. Wellcome Open Research 2 (11.12.2017): 116. http://dx.doi.org/10.12688/wellcomeopenres.13119.1.
Der volle Inhalt der QuelleGao, Fei, Maria Wesolowska, Reuven Agami, Koos Rooijers, Fabricio Loayza-Puch, Conor Lawless, Robert N. Lightowlers und Zofia M. A. Chrzanowska-Lightowlers. „Using mitoribosomal profiling to investigate human mitochondrial translation“. Wellcome Open Research 2 (29.01.2018): 116. http://dx.doi.org/10.12688/wellcomeopenres.13119.2.
Der volle Inhalt der QuelleFecher-Trost, Claudia, Ulrich Wissenbach, Andreas Beck, Pascal Schalkowsky, Christof Stoerger, Janka Doerr, Anna Dembek et al. „The in Vivo TRPV6 Protein Starts at a Non-AUG Triplet, Decoded as Methionine, Upstream of Canonical Initiation at AUG“. Journal of Biological Chemistry 288, Nr. 23 (23.04.2013): 16629–44. http://dx.doi.org/10.1074/jbc.m113.469726.
Der volle Inhalt der QuelleJewett, Mollie W., Sunny Jain, Angelika K. Linowski, Amit Sarkar und Patricia A. Rosa. „Molecular characterization of the Borrelia burgdorferi in vivo-essential protein PncA“. Microbiology 157, Nr. 10 (01.10.2011): 2831–40. http://dx.doi.org/10.1099/mic.0.051706-0.
Der volle Inhalt der QuellePaudel, Dinesh Babu, und Hélène Sanfaçon. „Mapping of sequences in the 5’ region and 3’ UTR of tomato ringspot virus RNA2 that facilitate cap-independent translation of reporter transcripts in vitro“. PLOS ONE 16, Nr. 4 (09.04.2021): e0249928. http://dx.doi.org/10.1371/journal.pone.0249928.
Der volle Inhalt der QuelleAlekhina, Olga, Ilya Terenin, Sergey Dmitriev und Konstantin Vassilenko. „Functional Cyclization of Eukaryotic mRNAs“. International Journal of Molecular Sciences 21, Nr. 5 (29.02.2020): 1677. http://dx.doi.org/10.3390/ijms21051677.
Der volle Inhalt der QuelleDissertationen zum Thema "Non-canonical initiation codon"
Condé, Lionel. „Contrôle traductionnel du SARS-CoV-2“. Electronic Thesis or Diss., Lyon, École normale supérieure, 2024. http://www.theses.fr/2024ENSL0010.
Der volle Inhalt der QuelleDuring viral infection, the regulation of gene expression is central to the complex interactions between the host and the pathogen. Viruses exploit the host's cellular machinery to ensure the synthesis of their proteins, which are necessary for replication and the spread of the infection. This is particularly the case with SARS-CoV-2 infection, which rapidly induces a global inhibition of cellular translation through the action of viral factors such as the Nsp1 protein. To efficiently produce its proteins, the virus must implement strategies to bypass this inhibition. The SARS-CoV-2 genome is expressed from 10 RNAs, the genomic RNA (gRNA) and 9 subgenomic RNAs that possess a common leader region but unique 5'UTR regions for each of the transcripts. My work focused on the structural elements that regulate the translation of the different SARS-CoV-2 RNAs.Through a series of in vitro (reticulocyte lysate) and in-cell experiments, we discovered that the translation efficiency varied significantly among the different viral RNAs. In particular, the genomic RNA, despite its complex structure, distinguishes itself by its remarkably high translation efficiency. We also determined that the SL1 stem-loop structure, present in all viral transcripts, was a major determinant for RNA expression and also played a crucial role in countering the inhibition induced by the Nsp1 viral protein. We established that translation initiation occurred through a cap-dependent mechanism and required the eIF4F complex. Finally, our study also characterized the role of two short upstream open reading frames (uORFs) found in certain 5'UTR regions of SARS-CoV-2 RNAs; these uORFs have variable impacts depending on their position
Knight, Helen Coral. „Alternative non-canonical translation initiation codons are used to synthesise novel isoforms of the transcription factor GATAD1“. Thesis, University of Southampton, 2017. https://eprints.soton.ac.uk/413444/.
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