Thematische Bibliographien / NDDs

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Auswahl der wissenschaftlichen Literatur zum Thema „NDDs“

Autor: Grafiati

Veröffentlicht am 30. Juni 2021

Zuletzt aktualisiert am 21. Juni 2025

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Zeitschriftenartikel zum Thema "NDDs"

Jiang, Yongxi, Tianxiu Lu, Jingmin Pi, and Waseem Anwar. "The Retentivity of Four Kinds of Shadowing Properties in Non-Autonomous Discrete Dynamical Systems." Entropy 24, no. 3 (2022): 397. http://dx.doi.org/10.3390/e24030397.

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In this paper, four kinds of shadowing properties in non-autonomous discrete dynamical systems (NDDSs) are discussed. It is pointed out that if an NDDS has a F-shadowing property (resp. ergodic shadowing property, d¯ shadowing property, d̲ shadowing property), then the compound systems, conjugate systems, and product systems all have accordant shadowing properties. Moreover, the set-valued system (K(X),f¯1,∞) induced by the NDDS (X,f1,∞) has the above four shadowing properties, implying that the NDDS (X,f1,∞) has these properties.

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Anilkumar, Adithya K., Puneet Vij, Samantha Lopez, et al. "Long Non-Coding RNAs: New Insights in Neurodegenerative Diseases." International Journal of Molecular Sciences 25, no. 4 (2024): 2268. http://dx.doi.org/10.3390/ijms25042268.

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Neurodegenerative diseases (NDDs), including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are gradually becoming a burden to society. The adverse effects and mortality/morbidity rates associated with these NDDs are a cause of many healthcare concerns. The pathologic alterations of NDDs are related to mitochondrial dysfunction, oxidative stress, and inflammation, which further stimulate the progression of NDDs. Recently, long non-coding RNAs (lncRNAs) have attracted ample attention as critical mediators in the pathology of NDDs. However, there is a significant gap in understanding the biological function, molecular mechanisms, and potential importance of lncRNAs in NDDs. This review documents the current research on lncRNAs and their implications in NDDs. We further summarize the potential implication of lncRNAs to serve as novel therapeutic targets and biomarkers for patients with NDDs.

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Toledo, Alma Rosa Lezama, Germán Rivera Monroy, Felipe Esparza Salazar, et al. "Gut–Brain Axis as a Pathological and Therapeutic Target for Neurodegenerative Disorders." International Journal of Molecular Sciences 23, no. 3 (2022): 1184. http://dx.doi.org/10.3390/ijms23031184.

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Human lifestyle and dietary behaviors contribute to disease onset and progression. Neurodegenerative diseases (NDDs), considered multifactorial disorders, have been associated with changes in the gut microbiome. NDDs display pathologies that alter brain functions with a tendency to worsen over time. NDDs are a worldwide health problem; in the US alone, 12 million Americans will suffer from NDDs by 2030. While etiology may vary, the gut microbiome serves as a key element underlying NDD development and prognosis. In particular, an inflammation-associated microbiome plagues NDDs. Conversely, sequestration of this inflammatory microbiome by a correction in the dysbiotic state of the gut may render therapeutic effects on NDDs. To this end, treatment with short-chain fatty acid-producing bacteria, the main metabolites responsible for maintaining gut homeostasis, ameliorates the inflammatory microbiome. This intimate pathological link between the gut and NDDs suggests that the gut-brain axis (GBA) acts as an underexplored area for developing therapies for NDDs. Traditionally, the classification of NDDs depends on their clinical presentation, mostly manifesting as extrapyramidal and pyramidal movement disorders, with neuropathological evaluation at autopsy as the gold standard for diagnosis. In this review, we highlight the evolving notion that GBA stands as an equally sensitive pathological marker of NDDs, particularly in Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis and chronic stroke. Additionally, GBA represents a potent therapeutic target for treating NDDs.

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Dr., C. S. Parameswari* K. Mounika B. Manasa N. Navya sree M. Sreya M. Rajeswari E. Anusha. "Review Article on Novel Drug Delivery System." International Journal of Pharmaceutical Sciences 2, no. 12 (2024): 1055–71. https://doi.org/10.5281/zenodo.14355738.

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The development of novel drug delivery systems (NDDS) has revolutionized the pharmaceutical industry by enhancing therapeutic efficacy, reducing side effects, and improving patient compliance. This thesis provides an overview of NDDS, classifying them into targeted, controlled, and modulated release systems. The significance of polymers in NDDS is highlighted, with a focus on natural, synthetic, biodegradable, conducting, and smart polymers. The advantages of NDDS, including increased bioavailability, reduced toxicity, and improved patient outcomes, are discussed. The thesis also explores various applications of NDDS, such as cancer therapy, tissue engineering, and gene delivery. Furthermore, the limitations and challenges associated with NDDS are addressed, emphasizing the need for continued research and development. This study contributes to the understanding of NDDS and their potential to transform the field of pharmaceuticals.

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Heuvel, M. Van den, C. Borkhoff, C. Koroshegyi, et al. "How Well Does the Nipissing District Developmental Screen (NDDS) Identify Communication Problems in Infants?" Paediatrics & Child Health 21, Supplement_5 (2016): e74-e74. http://dx.doi.org/10.1093/pch/21.supp5.e74.

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Abstract BACKGROUND: Communication problems are often the first presenting problem in infants with developmental disabilities. With early detection, intervention can start. The 18-month Nipissing District Developmental Screen (NDDS) was created as a developmental checklist for use in primary care. The Infant Toddler Checklist (ITC) is a validated questionnaire for detecting communication problems. Our objective was to examine how well the 18-month NDDS identifies communication problems. We therefore assessed the convergent validity of the 18-month NDDS with the ITC as a gold standard. OBJECTIVES: To examine how well the 18-month NDDS identifies communication problems. To compare parents’ answers to a similar question, “How many different words does your child use?”, on both checklists. DESIGN/METHODS: Healthy children (n = 348, 55% male, mean age 18.6 months, SD 0.7) were recruited during scheduled health supervision visits. Parents completed both the 18-months NDDS and ITC. We assessed the convergent validity of the 18-month NDDS with the ITC as a gold standard. Correlation (Spearman) and the level of agreement (Cohen’s kappa, sensitivity, specificity) were calculated. For our secondary outcome, we compared the percentage of agreement between the answers to the same question on both instruments. RESULTS: On the NDDS, 138 (39.7%) children had “one or more flags” (+1 NDDS) and 54 (15.8%) children had “two or more flags” (+2 NDDS). 13 (3.7%) infants had a concern on the total ITC score, 31 (8.9%) a speech-, 9 (2.6%) a social -, and 14 (4.0%) a symbolic concern.The +2 NDDS had a medium correlation (Spearman’s rho 0.42) and a fair agreement (Cohen’s kappa 0.32) with the ITC. Sensitivity and specificity of the NDDS using the +1 and + 2 flag cut-offs in detecting concerns compared with the ITC are shown in the table.The similar question about number of words spoken by 18-month old infants revealed agreement between the NDDS and ITC; 24.4% versus 30.8% of the 18-month old infants did not speak 20 words or more respectively. CONCLUSION: Infants with a severe overall communication delay were identified with the 18-months NDDS. The low sensitivity of the 2+ NDDS flag in detecting speech and social concerns suggests that infants who could benefit from early interventions may not be identified.The low specificity of the 1+ NDDS flag may cause unnecessary concerns for parents.For the early identification of all levels of communicationdelays, we recommend using a standardized questionnaire like the ITC.

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Banu, Laila Areju Man, FM Anamul Haque, and Saria Tasnim. "Neurodevelopmental Disorders (NDDs) in Children: Role of Maternal Factors." Bangladesh Journal of Obstetrics & Gynaecology 37, no. 2 (2023): 139–47. http://dx.doi.org/10.3329/bjog.v37i2.69033.

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Neurodevelopmental disorders (NDDs) are disabilities affecting normal brain development and function. The early stages of brain development are critical, and disruption of this process results in neurodevelopmental disorders (NDDs) in children. Common neurodevelopmental disorders in children include autism spectrum disease (ASD), attention deficit hyperactivity disorder (ADHD), cerebral palsy (CP), intellectual disability (ID), epilepsy, learning disability, schizophrenia etc. Though the causes of NDDs are multifactorial, epidemiological studies have shown that a number of maternal factors such as, diabetes, hypertension, obesity, maternal immune activation, infection, diet, genetics, lifestyle etc. also influence the development of NDDs. In this review, we focus on some common NDDs in children and the mechanism by which different maternal factors may contribute to the development of NDDs. With the increasing incidence of NDDs, it is urgent to mitigate the risk and severity of these conditions through both preventive measures in pregnancy and developing treatment strategies. Bangladesh J Obstet Gynaecol, 2022; Vol. 37(2): 139-147

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Wang, Li, Chao-Chao Yu, Xin-Yuan Liu, Xiao-Ni Deng, Qing Tian, and Yan-Jun Du. "Epigenetic Modulation of Microglia Function and Phenotypes in Neurodegenerative Diseases." Neural Plasticity 2021 (May 29, 2021): 1–13. http://dx.doi.org/10.1155/2021/9912686.

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Microglia-mediated neuroinflammation is one of the most remarkable hallmarks of neurodegenerative diseases (NDDs), including AD, PD, and ALS. Accumulating evidence indicates that microglia play both neuroprotective and detrimental roles in the onset and progression of NDDs. Yet, the specific mechanisms of action surrounding microglia are not clear. Modulation of microglia function and phenotypes appears to be a potential strategy to reverse NDDs. Until recently, research into the epigenetic mechanisms of diseases has been gradually developed, making it possible to elucidate the molecular mechanisms underlying the epigenetic regulation of microglia in NDDs. This review highlights the function and phenotypes of microglia, elucidates the relationship between microglia, epigenetic modifications, and NDDs, as well as the possible mechanisms underlying the epigenetic modulation of microglia in NDDs with a focus on potential intervention strategies.

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Sharifi-Rad, Mehdi, Chintha Lankatillake, Daniel A. Dias, et al. "Impact of Natural Compounds on Neurodegenerative Disorders: From Preclinical to Pharmacotherapeutics." Journal of Clinical Medicine 9, no. 4 (2020): 1061. http://dx.doi.org/10.3390/jcm9041061.

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Among the major neurodegenerative disorders (NDDs), Alzheimer’s disease (AD) and Parkinson’s disease (PD), are a huge socioeconomic burden. Over many centuries, people have sought a cure for NDDs from the natural herbals. Many medicinal plants and their secondary metabolites are reported with the ability to alleviate the symptoms of NDDs. The major mechanisms identified, through which phytochemicals exert their neuroprotective effects and potential maintenance of neurological health in ageing, include antioxidant, anti-inflammatory, antithrombotic, antiapoptotic, acetylcholinesterase and monoamine oxidase inhibition and neurotrophic activities. This article reviews the mechanisms of action of some of the major herbal products with potential in the treatment of NDDs according to their molecular targets, as well as their regional sources (Asia, America and Africa). A number of studies demonstrated the beneficial properties of plant extracts or their bioactive compounds against NDDs. Herbal products may potentially offer new treatment options for patients with NDDs, which is a cheaper and culturally suitable alternative to conventional therapies for millions of people in the world with age-related NDDs.

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Zhang, Xiaoyan, Weithye Lee, and Jinsong Bian. "Recent Advances in the Study of Na+/K+-ATPase in Neurodegenerative Diseases." Cells 11, no. 24 (2022): 4075. http://dx.doi.org/10.3390/cells11244075.

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Na+/K+-ATPase (NKA), a large transmembrane protein, is expressed in the plasma membrane of most eukaryotic cells. It maintains resting membrane potential, cell volume and secondary transcellular transport of other ions and neurotransmitters. NKA consumes about half of the ATP molecules in the brain, which makes NKA highly sensitive to energy deficiency. Neurodegenerative diseases (NDDs) are a group of diseases characterized by chronic, progressive and irreversible neuronal loss in specific brain areas. The pathogenesis of NDDs is sophisticated, involving protein misfolding and aggregation, mitochondrial dysfunction and oxidative stress. The protective effect of NKA against NDDs has been emerging gradually in the past few decades. Hence, understanding the role of NKA in NDDs is critical for elucidating the underlying pathophysiology of NDDs and identifying new therapeutic targets. The present review focuses on the recent progress involving different aspects of NKA in cellular homeostasis to present in-depth understanding of this unique protein. Moreover, the essential roles of NKA in NDDs are discussed to provide a platform and bright future for the improvement of clinical research in NDDs.

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Barman, Dhunusmita, Nikita Dey, Srijani Sen, Bibhuti Kakoti, and Catherine Vanlalhriatpuii. "Neuromodulatory effect of plant metabolites." Sciences of Phytochemistry 1, no. 1 (2022): 47–69. http://dx.doi.org/10.58920/sciphy01010047.

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Neurological disorders (NDDs) are diseases that affect the central and peripheral nervous systems. Gradual malfunction and destruction of the neurons or the nerve cells characterize them. Every year, NDDs affect millions of people worldwide. Over the years, several neuromodulatory techniques have been introduced to improve the quality of life for those affected by NDDs. NDDs are chronic and incurable conditions, however, bioactive substances derived from medicinal plants have emerged as the greatest choice for their prevention and treatment. Literature evidences several benefits of plant metabolites as alternative medicines for the prevention and treatment of NDDs. Numerous investigations have shown plant metabolites to possess beneficial biological effects because of their qualities, which include but are not limited to anti-inflammatory, antioxidant, and neuroprotective actions. Practices of folk medicine and several studies have also guided many phytopharmacological interventions toward the treatment of NDDs. This review aims to highlight secondary metabolites (alkaloids, flavonoids, steroids, terpenoids) of plants with neuroprotective action that could potentially play an important role in the prevention and management of NDDs.

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Dissertationen zum Thema "NDDs"

Carlström, Moa, and Vilija Kuusela. "Skolsköterskans hälsofrämjande arbete för elever med neuropsykiatriska funktionsnedsättningar : En kvalitativ intervjustudie." Thesis, Högskolan i Skövde, Institutionen för hälsovetenskaper, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-20052.

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Bakgrund: Elever med neuropsykiatriska funktionsnedsättningar (NPF) är i behov av stöd då de är extra känsliga för krav och press i skolan. Skolsköterskans primära uppgift är att stärka elevens välbefinnande genom att vara närvarande, lyssna och att vara delaktig i samtal. Skolsköterskan har, tillsammans med elevhälsan, till uppgift att arbeta hälsofrämjande för att bidra till att eleven lyckas i skolan. Skolsköterskorna som träffar eleverna under hälsobesök och korta spontana besök utför ett betydelsefullt arbete för att skapa tillit och förtroende hos eleven. Syfte: Syftet var att beskriva skolsköterskans erfarenhet av hälsofrämjande insatser bland elever med NPF. Metod: Kvalitativ metod med induktiv ansats användes i studien. Semistrukturerade intervjuer genomfördes med 10 skolsköterskor. Intervjuerna analyserades i enlighet med kvalitativ innehållsanalys. Resultat: Vid analysen identifierades två kategorier: Stödjande insatser och Samarbete. Stödjande insatser inkluderar att skapa en relation via samtal och möten samt skolmiljöanpassningar. Samarbete inbegriper samverkan med andra professioner samt delaktighet med vårdnadshavare och elev. Slutsats: Ett hälsofrämjande arbete uppnås genom samverkan inom elevhälsoteamet, skolsköterskans samarbete med vårdnadshavare samt genom att göra barnen med NPF delaktiga. Dessutom bidrar skolsköterskans lyhördhet till att stärka elevernas självkänsla.<br>Background: Students with neurodevelopmental disorders (NDDs) need support since they are extra vulnerable for pressure and demands from school. The school nurse's primary task is to strengthen the student’s well-being by being present, listening and being involved in conversations. The school nurse, together with the student health, has the task to work with health promotion to contribute to the student’s success in school. School nurses who meet students during health visits and short spontaneous visits performs an important work to create a trustful and confident relationships. Aim: The aim was to describe the school nurse's experience of health promotion efforts among students with NDDs. Method: The study is based on a qualitative method with an inductive approach. Data collection took place through semi-structured interviews of ten school-nurses. The analysis was performed with a qualitative content analysis. Results: In the analyze, two categories emerged: Supporting initiatives and Collaboration. Supporting initiatives includes create relationship through interactions and dialogue as well as adapting the school environment. Collaboration involves cross functional cooperation as well as involvement of parents and students. Conclusion: Health promotion is achieved through cooperation within the student health team, involving parents and by making the student with NDDs a part of the process. Moreover, does the school nurse recognition contribute to strengthen the students’ self-esteem.

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Silva, Paulo Marcelo de Avellar. "Estudo da aplicação de naftaleno-diimidas para o desenvolvimento de sensores e dispositivos: eletroquimica de eletrodos modificados de carbono vítreo e compósitos com nanotubos de carbono." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/46/46132/tde-24082007-081716/.

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Foram sintetizadas quatro naftaleno-diimidas (NDIs) funcionalizadas com grupos N-alquil-amino e N-alquil-hidroxi. Essas espécies foram caracterizadas pelos métodos espectrométricos convencionais. As propriedades eletroquímicas destas NDIs foram estudadas por voltametria cíclica em acetonitrila e N-metil-pirrolidona. Os voltamogramas obtidos mostram dois processos redox reversíveis com E1/2 ao redor de -970 mV e de -1400 mV (vs fc/Fc+). Estes resultados são consistentes com trabalhos previamente reportados. Algumas das NDIs exibiram grande afinidade por superfícies de carbono vítreo anodizado, adsorvendo irreversivelmente. Esta propriedade foi explorada na obtenção de eletrodos modificados. As propriedades eletroquímicas de eletrodos de carbono vítreo modificados por adsorção das NDIs foram investigadas por voltametria cíclica (VC) e cronoamperometria de degrau de potencial (CADP). Os voltamogramas são caracterizados pela presença de um único processo redox reversível, com E1/2 na faixa de -360 mV a -385 mV (vs Ag/AgCl). Os transientes de CADP forneceram estimativas para as constantes de velocidade k para as reações de transferência de elétrons na superfície dos eletrodos. Foram observados desvios em relação à cinética de primeira ordem, atribuídos ao caráter micro-heterogêneo da superfície. O modelo de Albery, que considera a dispersão dos valores de k, foi aplicado e comparado com dados obtidos por ajuste de funções exponenciais. Foram também preparados compósitos à base de NDIs e nanotubos de carbono de parede simples (NTCPS) sobre eletrodos de ouro. A resposta voltamétrica dos compósitos NDI/NTCPS é caracterizada pela presença de um processo redox reversível na faixa de -336 mV a -349 mV (vs Ag/AgCl). A cinética de transferência de elétrons nestes eletrodos modificados foi estudada por metodologia análoga à descrita anteriormente. Os resultados sugerem que os eletrodos estudados podem encontrar aplicação no desenvolvimento de sensores químicos, dispositivos eletroquímicos e em eletrocatálise.<br>Four naphthalene-diimides (NDIs) were synthesized functionalyzed with N- alkyl-amino and N-alkyl-hydroxi groups. These NDIs were characterized by conventional spectrometric methods. The electrochemical properties of NDIs were studied through cyclic voltametry in acetonitrile and N-metyl-pyrrolidone. Typical voltammograms present two reversible redox processes with E1/2 around -970 mV and -1400 mV (vs Fc/Fc+ ). These results are consistent with previous reported works. Some NDIs showed a strong affinity to anodized glassy carbon surfaces, with irreversible adsorption. This property was used to obtain new modified glassy carbon electrodes. The electrochemical properties of glassy carbon electrodes modified by adsorption of the NDIs were studied by cyclic voltammetry (CV) and potential step chronoamperometry (PSCA). The voltammograms are characterized by the presence of a single reversible redox process, with E1/2 around -360 mV to -385 mV (vs Ag/AgCl). The PSCA transients offered estimates for the k rate constants for the electron transfer reactions on the electrode surfaces. Deviations with respect to the first order kinetics were observed and considered due to the micro-heterogeneity of the surface. Albery´s model, wich takes into account the dispersion in k values, was applied and results compared with those obtained by exponential functions fitting. Composites based on NDIs and single walled carbon nanotubes (SWNT) were also prepared on gold electrodes. The voltammetric response from NDI/SWNT composites is characterized by the presence of reversible redox process in the range from -336 mV to -349 mV (vs Ag/AgCl). The kinetics of the electron transfers on those modified electrodes was studied using a methodology similar to the one previously described. The results suggest that these modified electrodes may find application in the development of chemical sensors, electrochemical devices and in electrocatalysis.

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Scholten, Mirjam. "Semiempirische Verfahren mit Orthogonalisierungskorrekturen: die OM3-Methode." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=967348765.

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Bouet, Jean-Yves. "Caractérisation du gène ndd du bactériophage T4. Etude de l'effet de la protéine NDD sur le nucléoi͏̈de bactérien." Toulouse 3, 1996. http://www.theses.fr/1996TOU30139.

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Chez la bacterie escherichia coli, l'adn genomique est constitue d'une molecule circulaire de 4,6 10#6 paires de bases. Cette molecule d'adn doit etre organise pour permettre a la fois sa condensation dans la cellule et les activites transcriptionnelles et replicatives continuelles caracteristiques des procaryotes. Cependant l'organisation generale des chromosomes bacteriens est encore largement enigmatique. Les travaux presentes dans ce memoire s'inscrivent dans le cadre de l'analyse a grande echelle du nucleoide bacterien. Nous nous sommes interesse a l'etude d'un phenomene physiologique induit par le bacteriophage t4, la disruption nucleaire. En effet, en quelques minutes, le produit du gene phagique ndd est capable de detruire completement l'organisation du nucleoide. La proteine ndd pourrait donc etre un moyen d'investigation de la structure et de l'organisation du chromosome bacterien. L'introduction generale presente les donnees acquises concernant la structure et l'organisation du chromosome bacterien. Les principaux resultats obtenus au cours de ce travail sont publies. Le premier article (gene, 1994) concerne l'identification du gene ndd et sa conservation importante parmi l'ensemble de la famille des bacteriophages t-pairs. Le second article (mol. Microbiol. , 1996) presente les effets physiologiques de l'expression du gene ndd clone. Les resultats obtenus ont permis de montrer que la proteine ndd est, a elle seule, capable de provoquer le phenomene de disruption nucleaire. Cette desorganisation complete du nucleoide, accompagnee d'une importante letalite des cellules, est realise sans la moindre destruction de l'adn chromosomique. L'ensemble des resultats est consistant avec une alteration specifique d'elements structuraux du nucleoide provoquee par la proteine ndd. D'autre part, l'etude de la proteine ndd thermosensible a permis de montrer qu'elle possede, in vitro, une activite de liaison a l'adn double brin. Les donnees presentees dans ce memoire sont discutees dans le dernier chapitre. Elles confirment amplement notre hypothese d'utiliser ndd comme moyen d'investigation de la structure du chromosome bacterien

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Langmead, Ruth. "The National Disability Insurance Scheme (NDIS) and mental health: A policy analysis." Thesis, Langmead, Ruth (2018) The National Disability Insurance Scheme (NDIS) and mental health: A policy analysis. Masters by Coursework thesis, Murdoch University, 2018. https://researchrepository.murdoch.edu.au/id/eprint/45888/.

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The National Disability Insurance Scheme (NDIS) is a landmark policy commitment made by the Australian Government in 2013. The NDIS has established market mechanisms to support the delivery of services that, according to the National Disability Insurance Agency, offer participants both choice and control. The NDIS is also remarkable as being the first disability policy that has included mental health (referred to as psychosocial disability). There is a large financial commitment to delivering the NDIS, with a projected $22 billion investment by 2020 when full national roll-out is achieved; it is therefore necessary to analyse if the policy is effective in delivering the outcomes it promises. The aetiology of impairment in mental health conditions is largely positioned within the social, economic, systemic and political environments, the primary impact of which can be observed as stigma. This aetiology of impairment necessitates that policy promising to offer a better life to people living with mental health conditions, must have ecological frameworks central to policy mechanisms. It is imperative to understand what the NDIS policy foundations are to analyse if it is a viable alternative to current service delivery for people living with mental health conditions. A policy analysis is presented in two parts; firstly, a discourse analysis is undertaken that provides an historical context to the problem and further identifies the theoretical assumptions embedded in the policy foundations. Secondly, an analysis of the effectiveness of the NDIS in achieving its desired outcomes for psychosocial disability is measured against economic and social criteria. It is identified that the NDIS is a policy founded on strong neoliberal ideologies and whilst an ecological perspective is occasionally cited within policy material it is not supported within a market driven service delivery model. Due to the NDIS rollout being in its infancy there is a dearth of research around its effectiveness, this policy analysis identifies that there is a critical need for such research. Future research must specifically focus on outcomes for people with mental health conditions to advise on the need for ecological frameworks as an economically efficient and socially inclusive alternative.

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Diksha, Khadka Pramote Prasartkul. "Abortion complications among women of reproductive age in Nepal : evidence from NDHS 2006 /." Abstract, 2008. http://mulinet3.li.mahidol.ac.th/thesis/2551/cd419/5037965.pdf.

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Faklaris, Orestis. "Photoluminescent diamond nanoparticles as labels in cells : study of their optical properties and investigation of their cellular uptake mechanism." Cachan, Ecole normale supérieure, 2009. http://tel.archives-ouvertes.fr/tel-00439561/fr/.

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Ce travail de thèse porte sur l'utilisation des NanoDiamants Photoluminescents (NDPs) pour des applications en bio-imagerie. Les nanodiamants (NDs) sont photoluminescents grâce à la présence de centres colorés azote-lacune (NV) dans leur maille cristalline. Le manuscrit est divisé en deux parties. La première concerne l'étude des propriétés optiques des centres colorés NV dans des NDs. Après l'optimisation de la concentration des centres NV, nous comparons la photoluminescence des NDPs à celle des nanoparticules semi-conductrices commerciales; nous concluons qu'elle peut être équivalente, même supérieure dans le cas des NDPs. Pour augmenter le contraste d'imagerie intracellulaire des NDPs, nous avons étudié l'excitation à 2-photons des centres NV. Lors de cette étude avec un laser impulsionnel, nous avons découvert que le signal de photoluminescence des NDPs excité à un photon chute très fortement lorsque l'impulsion infrarouge est simultanée de l'excitation visible. Nous avons étudié la façon d'utiliser cet effet pour l'imagerie de super-resolution. La deuxième partie porte sur l'étude des applications des NDPs comme sondes pour la bio-imagerie. Dans le but d'utiliser des NDPs comme véhicules de biomolécules, nous avons étudié leurs mécanismes d'internalisation et avons élucidé leur localisation intracellulaire, en inhibant des voies différentes d'internalisation et par des expériences d'immunofluorescence. De plus, nous avons montré que les NDPs ne sont pas toxiques pour des cellules en culture. Un premier essai de vectorisation a été mené avec de NDPs couverts d'ADN plasmidique<br>This thesis work studies the use of Photoluminescent NanoDiamonds (PNDs) for bio-imaging applications. Nanodiamonds are photoluminescent thanks to embedded nitrogen-vacancy (NV) color centers. The thesis is divided in two parts. The first part concerns the study of the optical properties of NV color centers in nanodiamonds. After optimization of the NV center concentration, we compared the photoluminescence of PNDs to commercial Quantum Dots (QDs) and conclude that it can be similar or even higher in the case of PNDs. To enhance the imaging contrast of internalized by cells PNDs, we studied the 2-photon excitation properties of NV centers. While implementing a pulsed excitation laser, we discovered that simultaneous one- and two-photon excitation (IR+VIS pulses) quenches the photoluminescence signal of PNDs. We examined how this effect can serve for super-resolution imaging of NV color centers in nanodiamonds. The second part of the work is devoted to the applications of PNDs as bio-imaging probes. In the prospect of applications of PNDs as drug delivery vehicles, we studied the uptake mechanisms of PNDs and elucidated their intracellular localization by blocking different entry mechanisms and by immunofluorescence experiments. Moreover, we ensured that PNDs are not toxic for cells in culture. As a first try of vectorization we covered PNDs with plasmid DNA and examined the transfection efficiency

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Johnson, Edward. "An exploration of person-centred allied health supports with rural and remote families in the context of the rollout of the National Disability Insurance Scheme in Australia." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27208.

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Australia has recently undergone a revolution in how people with disabilities access funding and choose supports – from supports administered or overseen by state/territory governments, to a national approach where individualised funding is allocated to people based on specific needs under the National Disability Insurance Scheme (NDIS). The power is now in the hands of the person with a disability, which has significant implications for consumers, clinicians and the business models of service providers. In rural and remote Australia, there has long been difficulty in accessing timely, person-centred disability supports and allied health services. Many families have continued to face these difficulties in the leadup to the NDIS transition, and following its implementation across Australia. The research undertaken in this thesis sought to understand family perspectives on past experiences of accessing allied health disability supports, their understanding of the language used to describe and deliver those services, and their expectations for the future given the sweeping changes in legislation and policy. Further, the research sought to use these data to inform at least one kind of solution – a solution which would make timely and person-centred allied health supports possible in rural and remote areas when there is a lack or shortage of existing local clinicians or clinical expertise. The research was carried out in two phases. In Phase 1, qualitative methods (semistructured interviews) were used to collect data from the parents or carers of children with intellectual disabilities in rural and remote Australia. The first study within this phase (Study 1) examined how families have experienced disability supports in the past and how they understood the principles applied in the design of those supports. The second study in this phase (Study 2) collected information regarding the families’ visions for the future. These data informed Phase 2 of the research. In Phase 2, four in-depth mixed methods case studies were carried out to examine the viability of delivering a person-centred allied health service to families in rural and remote Australia via a hybrid online and in person capacity-building approach (Study 3). Families identified a number of issues which affected their past experiences and expectations for the future. The in-depth case studies showed that a hybrid online and in-person capacity-building approach can be effective in some situations, and less effective in others, with one key factor of success including local key-worker support and expertise. With the expansion of digital service delivery models in 2020 as a result of the COVID- 19 pandemic, this research begins to build a foundation for further investigation of capacity-building approaches beyond a traditional one-to-one, in-person-only therapy delivery process. It has the potential to support policy and practice advancement in rural and remote communities across Australia and the world into the future.

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PATEL, LINIA. "THE MEDIATING EFFECT OF INCOME AND EDUCATION USING THE UK NATIONAL AND DIETARY SURVEY (NDNS) DATA." Doctoral thesis, Università degli Studi di Milano, 2021. http://hdl.handle.net/2434/816793.

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Diet substantially contributes to socioeconomic inequalities in cardiovascular morbidity and mortality. High adherence to the dietary approach to stop hypertension (DASH) has been proved effective in lowering blood pressure in patients with cardiovascular disease (CVD) as well as to prevent CVD risk factors in the general population. Little is known about time trends in diet quality and associated inequalities in the United Kingdom (UK). In addition, the causal pathway between education and dietary choices has not been fully explained and the role of income in preventing a healthy diet has not been clarified. This doctorate firstly, aimed to quantify the differences in adherence to the DASH in relation to socioeconomic position (SEP) in the UK and to evaluate recent trends. Secondly, it aimed to quantify the mediating effect of income on the relationship between education and the DASH score in the UK population. Data used for analysis was obtained from three waves of the National Diet and Nutrition Survey Rolling Programme (NDNS) 2008-2012, 2013-2014 and 2015-2016). The DASH score was calculated based on Fung et al methodology and was calculated using sex-specific quintiles of DASH items. For the first part of the analysis (Paper 2) data analysis included 6435 subjects aged 18 and older who participated in the NDNS. Multiple linear regressions were used to evaluate the relationship between the socioeconomic variables and the DASH score. Quantile regression analysis was used to model the median intake of each component as a function of the socioeconomic variable and the survey year. In the second analysis (Paper 3), analysis was done on 4864 subjects aged 18 and older. Counterfactual-based mediation analysis was carried out to decompose the total effect of education on DASH score into average direct effect (ADE) and average causal mediation effect (ACME) mediated by income. A gradient relationship between the DASH score and all socioeconomic variables emerged with increasing values of the score at higher socioeconomic positions (SEP effect p value: <0.0001 for education, occupation, and income) in the initial analysis. The interaction term between survey year and the socioeconomic variables was not significant showing that the trend was not different across socioeconomic groups (p >0.05). The estimated difference between people with no qualification and those having the highest level of education was -3.59 points (95% CI: -3.91; -3.20). The difference between people engaged in routine occupations and those engaged in high managerial and professional occupations was -3.40 points (95% CI: -3.87; -2.92), and the difference between subjects in the first fifth and last fifth of the household income distribution was -2.73 points (95% CI: -3.16; -2.29). The widest socioeconomic differences emerged for consumption of fruit, vegetables, whole grains, nuts, seeds and legumes. Mediation analysis indicated that the overall mediating effect of income on the relationship between education and the DASH score was only partial, with an estimated proportion mediated ranging between 6 to 9%. The mediating effect was higher among women (11.6%) and younger people (17.9%). Findings from this doctorate add an important contribution to the existing literature and more importantly, provide an updated picture of socio-economic inequalities in diet amongst UK adults in context of the whole diet. The results show that overall, the DASH score increased over time, yet the overall score remains low. Moreover, persistent disparities between individuals with higher versus lower SEP were observed. Additional analysis indicates that low income plays a modest role in explaining educational differences in the UK population. Further research is needed to investigate which other factors may explain differences in diet quality. In conclusion, findings in this doctorate have substantial implications for public nutrition policy. An immediate implication is the need for public nutrition policies that are individualised to SEP. Targeted interventions for those within the lower SEP need a multi-factorial approach not just focusing on the cost of food but on other factors such as nutrition literacy, attitudes towards healthy eating as well as access to healthy food. Further research is needed to fully investigate which other factors may explain the socioeconomic inequality in the adoption of the DASH diet in UK. THE THESIS IS BASED ON THE FOLLOWING PUBLISHED PAPERS 1. Patel,L.Alicandro,G,LaVecchia,C(2018).Low-CalorieBeverageConsumption, Diet Quality and Cardiometabolic Risk Factors in British Adults. Nutrients, 10 2. Patel L, Alicandro G, La Vecchia C (2020) Dietary approach to stop hypertension (DASH) diet and associated socioeconomic inequalities in the United Kingdom. Br J Nutr, 1-24. – AWARDED UK NUTRITION SOCIETY PAPER OF THE MONTH JUNE 2020. 3. Patel L, Bertuccio P, Alicandro G, La Vecchia C (2020). Educational inequality in the dietary approach to stop hypertension (DASH) diet in the UK: evaluating the mediating role of income. Br J Nutr, 1-20

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Johnsson, Genevieve Catherine. "Technology Delivered Disability Training and Support for Service Providers in Regional and Remote New South Wales." Thesis, The University of Sydney, 2019. http://hdl.handle.net/2123/20489.

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The rollout of individualised disability funding in Australia will result in an increased demand for services for Australians with a disability. Growing and maintaining a skilled workforce will be vital in keeping up with the increased demand for disability-related support. Continuing professional development is one way to build capacity, however face-to-face opportunities can be limited in more remote areas in Australia. Technology may provide a low-cost and widely-accessible platform for training and supporting rural and remote staff. The studies in this thesis are a realist evaluation of a novel webinar training and individual online support program to upskill a diverse range of participants including allied health, education and community support staff. Surveys and interviews were conducted to investigate what is it about the program works, for whom, and in which conditions. We found a statistically significant increase in perceived skills and knowledge, and confidence in working with children with autism from pre- to post-program, and this increase was positively related to the number of webinars the participants accessed. The mode of webinar access was predominantly via asynchronous learning (watching recording of webinars). These results were consistent across job roles and levels of remoteness. Synchronous learning via individual sessions was accessed by a small number of participants, mostly allied health professionals. Increased collaboration and access to autism-specific support were reported benefits of participating in the training program, while barriers for engagement included work load and scheduling. Occupational stress was found to be within normal limits across the sample and duration of the program. The technology platform was found to be accessible and acceptable. The results indicate that online technology may provide professionals in geographically isolated areas with improved access to learning and support that increases their skills.

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Bücher zum Thema "NDDs"

Society, National Deaf Children's, ed. NDCS technology services. NDCS, 2000.

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Minaev, B. A. NDS: Aktualʹnye voprosy. Glavbukh, 1999.

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Hughes, Jeffrey F. NDS for NT. IDG Books Worldwide, 1998.

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National Disaster Medical System (U.S.), ed. NDMS, catastrophic care for the nation. National Disaster Medical System, 1999.

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Luis, Hernández Otero Ricardo, ed. NDCS, nuevo diccionario cubano de seudónimos. Rogés Llibres, 2000.

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Jeffrey, Harris, ed. Administering NDS corporate edition. McGraw-Hill, 2000.

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Ukraine. NDS: Sbornik sistematizirovannogo zakonodatelʹstva. "Faktor", 2005.

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Andrew, Chris. Novell's NDS developer's guide. Novell Press, 1999.

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(Canada), NDSS Steering Committee. National Diabetes Surveillance System (NDSS) business plan. 3rd ed. Health Canada, 2000.

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Konstantinov, V. N. Ischislenie NDS predprii͡a︡tii͡a︡mi razlichnykh otrasleĭ. Glavbukh, 1998.

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Buchteile zum Thema "NDDs"

Moreau, Clara, Christine Deruelle, and Guillaume Auzias. "Machine Learning for Neurodevelopmental Disorders." In Machine Learning for Brain Disorders. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3195-9_31.

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AbstractNeurodevelopmental disorders (NDDs) constitute a major health issue with >10% of the general worldwide population affected by at least one of these conditions—such as autism spectrum disorders (ASD) and attention deficit hyperactivity disorders (ADHD). Each NDD is particularly complex to dissect for several reasons, including a high prevalence of comorbidities and a substantial heterogeneity of the clinical presentation. At the genetic level, several thousands of genes have been identified (polygenicity), while a part of them was already involved in other psychiatric conditions (pleiotropy). Given these multiple sources of variance, gathering sufficient data for the proper application and evaluation of machine learning (ML) techniques is essential but challenging. In this chapter, we offer an overview of the ML methods most widely used to tackle NDDs’ complexity—from stratification techniques to diagnosis prediction. We point out challenges specific to NDDs, such as early diagnosis, that can benefit from the recent advances in the ML field. These techniques also have the potential to delineate homogeneous subgroups of patients that would enable a refined understanding of underlying physiopathology. We finally survey a selection of recent papers that we consider as particularly representative of the opportunities offered by contemporary ML techniques applied to large open datasets or that illustrate the challenges faced by current approaches to be addressed in the near future.

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Agarwal, Vinayak, Divya Jindal, Shriya Agarwal, Shalini Mani, and Manisha Singh. "Initiation of Neurodegenerative Disorders (NDDs) Through Metal Toxicity Generated Oxidative Stress." In Free Radical Biology and Environmental Toxicity. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83446-3_12.

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Singh, Manisha, and Divya Jindal. "Recent Advances in Nanoformulation-Based Intranasal Delivery of Bioactive Compounds and Biologics for Neurodegenerative Disorders (NDDs)." In Lecture Notes in Mechanical Engineering. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-3386-0_6.

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Akhter, Firoz, Asma Akhter, and Saheem Ahmad. "Toxicity of Protein and DNA-AGEs in Neurodegenerative Diseases (NDDs) with Decisive Approaches to Stop the Deadly Consequences." In Perspectives in Environmental Toxicology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-46248-6_5.

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Cowden, Mhairi, Claire McCullagh, and Jennifer Tran. "The NDIS Trials." In The National Disability Insurance Scheme. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2244-1_5.

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Gil’, Michael I. "Linear Autonomous NDEs." In Atlantis Studies in Differential Equations. Atlantis Press, 2014. http://dx.doi.org/10.2991/978-94-6239-091-1_5.

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Gil’, Michael I. "Nonlinear Vector NDEs." In Atlantis Studies in Differential Equations. Atlantis Press, 2014. http://dx.doi.org/10.2991/978-94-6239-091-1_7.

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Suski, W., and T. Palewski. "(NdS)1.16TaS2." In Pnictides and Chalcogenides II. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713485_212.

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Suski, W., and T. Palewski. "(NdS)1.17TaS2." In Pnictides and Chalcogenides II. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713485_213.

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Suski, W., and T. Palewski. "(NdS)1.18NbS2." In Pnictides and Chalcogenides II. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/10713485_215.

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Konferenzberichte zum Thema "NDDs"

Montesinos, Victor, Jing Song, Wei-Hong Liang, Eulogio Oset, Juan Nieves, and Miguel Albaladejo. "$NDD^∗$ three-body molecular states." In 10th International Conference on Quarks and Nuclear Physics. Sissa Medialab, 2025. https://doi.org/10.22323/1.465.0045.

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Kim, Ju-Chan, Pham Van Nguyen, Duc-Tai Le, and Hyunseung Choo. "NDAS: Noise-Decomposed Abnormal Segmentation for Robust Medical Image Retrieval." In 2025 19th International Conference on Ubiquitous Information Management and Communication (IMCOM). IEEE, 2025. https://doi.org/10.1109/imcom64595.2025.10857580.

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Gómez, N., C. Hernández B, J. Villar, et al. "Comparative Analysis of the Accuracy of NDTs in Determining Concrete Strength." In 2024 9th International Engineering, Sciences and Technology Conference (IESTEC). IEEE, 2024. https://doi.org/10.1109/iestec62784.2024.10820279.

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Chagas, Ana Luísa de Bastos, Giordana de Farias F. B. Bucci, Juliana Paula Félix, Rogerio Salvini, Hugo Nascimento, and Fabrizzio Soares. "Exploring Biases in Machine Learning Models for Neurodegenerative Diseases Diagnosis Through Gait and Voice Analysis." In Anais Estendidos do Simpósio Brasileiro de Computação Aplicada à Saúde. Sociedade Brasileira de Computação (SBC), 2025. https://doi.org/10.5753/sbcas_estendido.2025.7498.

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This work examines potential biases in machine learning models for diagnosing neurodegenerative diseases (NDDs) through gait and voice analysis. It investigates how common techniques, such as gait signal windowing and using multiple voice samples per individual indiscriminately, can lead to inflated performance estimates when samples from the same individual are treated independently. Using two public databases, it compares scenarios where augmented samples are treated independently versus grouped by individual. Results show that independent treatment leads to artificially higher performance metrics. The findings highlight the need for proper intra-individual variability handling to ensure reliable clinical decision support for NDD diagnosis.

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Félix, Juliana Paula, Hugo A. D. do Nascimento, and Nilza Nascimento Guimarães. "Investigation of Machine Learning Techniques to Aid in the Diagnosis of Neurodegenerative Diseases." In Anais Estendidos do Simpósio Brasileiro de Computação Aplicada à Saúde. Sociedade Brasileira de Computação (SBC), 2024. http://dx.doi.org/10.5753/sbcas_estendido.2024.2828.

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The thesis summarized in this document introduces alternative, rapid, low-cost, and effective solutions, aided by machine learning techniques, to support the diagnosis and differentiation of neurodegenerative diseases (NDDs) such as Parkinson’s Disease, Huntington’s Disease, and Amyotrophic Lateral Sclerosis. These diseases, characterized by the progressive loss of neurons, have no cure, and diagnosis is predominantly clinical. By leveraging novel features extracted from gait signals through dynamic fluctuation analysis and harmonic distortion, the thesis achieves highly accurate results with specificity and sensitivity ranging from 96% to 100% for automatic NDD classification, serving as a diagnostic aid system. Furthermore, it presents and discusses an innovative approach to NDD diagnosis focused on the patient’s well-being, aiming to reduce examination duration and physical effort required for gait signal collection. These contributions represent innovations in the computational field with the potential to positively impact public health and enhance the quality of life of people with neurodegenerative diseases.

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"nDS 2007." In 2007 International Workshop on Multidimensional (nD) Systems. IEEE, 2007. http://dx.doi.org/10.1109/nds.2007.4509524.

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"nDS 2007 Committees." In 2007 International Workshop on Multidimensional (nD) Systems. IEEE, 2007. http://dx.doi.org/10.1109/nds.2007.4509529.

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Invernizzi, Diletta Colette, Giorgio Locatelli, Naomi J. Brookes, and Martin Grey. "Similar but Different: A Top-Down Benchmarking Approach to Investigate Nuclear Decommissioning Projects." In 2017 25th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icone25-66155.

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Project management literature has, until now, mainly focused on new build and only in the last decades the issues of decommissioning (mega) projects has arisen. To respond to this changing environment, project management will need to understand the challenges of decommissioning projects. Decommissioning projects within Oil & Gas, Chemical and Nuclear sectors are characterized by high costs, long schedules and uncertainty-based risks. The budget for Nuclear Decommissioning Projects and Programmes (NDPs) are subject to well publicized increases and, due to their relatively recent emergence, complexity and variety, key stakeholders lack a full understanding of the key factors influencing these increases. Benchmarking involves “comparing actual or planned practices [...] to identify best practices, generate ideas for improvement” [1] and offers significant potential to improve the performance of project selection, planning and delivery. However, even if benchmarking is the envisaged methodology to investigate the NDPs characteristics that impact on the NDPs performance, until now, it has only been partially used and there is a huge gap in the literature concerning benchmarking NDPs. This paper adapts a top-down benchmarking approach to highlight the NDPs characteristics that mostly impact on the NDPs performance. This is exemplified by a systematic quantitative and qualitative cross-comparison of two major “similar-but-different” NDPs: Rocky Flats (US) and Sellafield (UK). Main results concern the understanding of the alternatives of the owner and/or the contractors in relation to (1) the physical characteristics and the end state of the nuclear site, (2) the governance, funding & contracting schemes, and (3) the stakeholders’ engagement.

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Wang, Hengyu, Min Zou, Robert L. Jackson, Preston R. Larson, and Matthew B. Johnson. "Nanoindentation on a Ni Nanodot-Patterned Surface." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70147.

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Nanoindentation on a Ni nanodot-patterned surface (NDPS) was investigated experimentally and numerically. The Ni NDPS consists of well-ordered arrays of Ni nanodots with approximately the same size and shape. The nanoindentation experiments were performed on the Ni NDPS using diamond tips of 1 and 5 μm radii of curvature. To efficiently simulate large number of nanodots in contact, numerical simulations were carried out using formulae empirically fitted from a finite element (FE) study of a single spherical contact. The simulation results were found to be in good agreement with the experimental results.

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Chen, Shuo, Junwei Cao, and Lipeng Zhu. "NDSS: A Named Data Storage System." In 2015 International Conference on Cloud and Autonomic Computing (ICCAC). IEEE, 2015. http://dx.doi.org/10.1109/iccac.2015.12.

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Berichte der Organisationen zum Thema "NDDs"

Schempf, H. RoboCon: Operator interface for robotic applications. Final report: RoboCon electrical interfacing -- system architecture, and Interfacing NDDS and LabView. Office of Scientific and Technical Information (OSTI), 1998. http://dx.doi.org/10.2172/674604.

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Childress, Sam, John Doe, Andrew Jackson, et al. NOvA Near Detector On the Surface (NDOS). Office of Scientific and Technical Information (OSTI), 2011. http://dx.doi.org/10.2172/1296761.

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Richards, Robin. Key Lessons from Developing Countries for National Development Bank Effectiveness. Institute of Development Studies, 2025. https://doi.org/10.19088/k4dd.2025.030.

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This rapid evidence review examines the major lessons for national development bank (NDB) effectiveness in developing countries. The review also investigates the objectives and key features of NDBs. The review focusses on how NDBs are funded, the products and services they offer and the role they play in developing countries. Lessons from case studies are used to highlight the challenges and successes of NDBs and how these challenges are mitigated.

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Carreras, Marco, Stephany Griffith-Jones, José Antonio Ocampo, Jiajun Xu, and Anne Henow. Implementing Innovation Policies: Capabilities of National Development Banks for Innovation Financing. Inter-American Development Bank, 2022. http://dx.doi.org/10.18235/0004390.

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This comparative note describes common and distinct practices on capabilities to support the innovation activities of seven national development banks (NDB): BNDES (Brazil), CORFO (Chile), China Development Bank, CDB (China), BANCOLDEX (Colombia), Bpifrance (France), Korean Development Bank, KDB (South Korea), and NAFINSA (Mexico). The analysis studies the strategies followed by the selected NDBs for the design and implementation of innovation support programs and the capacities they need to be successful. Little is known about the experience of these NDBs in the world that have been the most successful in designing and implementing programs to support innovation. Building on the primary data collected through flexible semi-structured interviews with current or former NDBs officials, validated and supplemented by interviews with stakeholders outside the NDB, this study asks the following research questions: (i) What priority do NDBs assign to the financing of innovation projects?; (ii) Which operational models would be most effective in financing high-potential innovation projects, avoiding capture? Should they operate on the first and/or second tier?; (iii) What capabilities(a) governance; (b) technical (financial and technological); and (c) operational (implementation and sustainability)should NDBs develop to support innovation credit?; (iv) how, based on their contact with clients, can NDBs help identify market failures faced by innovative companies and thus produce and organize information on potential projects with high social returns?; and (v) What is the best framework for coordinating the work of the NDBs with the innovation agencies?

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Jones, Natalie, Cleo Verkuijl, Miquel Muñoz Cabré, and Georgia Piggot. Connecting the dots: mapping references to fossil fuel production in national plans under the UNFCCC for the 2023 Global Stocktake. Stockholm Environment Institute, 2023. http://dx.doi.org/10.51414/sei2023.040.

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Fossil fuel production must wind down significantly to achieve the long-term temperature goals of the Paris Agreement. How countries have addressed the issue of fossil fuel production in national communications to the UN Framework Convention on Climate Change (UNFCCC), however, has not received extensive attention from the climate community. This report remedies this gap by reviewing nationally determined contributions (NDCs) and longterm low-emissions development strategies (LT-LEDS) countries submitted under the UNFCCC. We show that while more countries have explicitly addressed fossil fuel production in NDCs over time, this has mostly related to continued or expanded production, with little mention of efforts to prepare for a transition away from fossil fuel reliance. Only a small number of countries have used NDCs and LT-LEDS as a space to plan for and communicate policies to support a managed transition away from fossil fuel production. This report contributes to the 2023 Global Stocktake by providing an inventory of how fossil fuel production has been discussed in NDCs and LT-LEDS to date, and by establishing a benchmark by which to assess further rounds of international climate plans and commitments. This also provides a useful tool for policy-makers when developing future NDCs and LT-LEDS.

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Jones, Natalie, Miquel Muñoz Cabré, Georgia Piggot, and Michael Lazarus. Tapping the potential of NDCs and LT-LEDS to address fossil fuel production. Stockholm Environment Institute, 2021. http://dx.doi.org/10.51414/sei2021.010.

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The need for a managed transition away from fossil fuel production raises the question of whether and how countries are addressing this need in their national communications to the UN Framework Convention on Climate Change (UNFCCC). A previous 2019 analysis of the first round of nationally determined contributions (NDCs) and long-term, low-emissions development strategies (LT-LEDS) found that few countries discussed how they would address fossil fuel production as part of their climate mitigation activities. Here, we examine new and updated NDCs and LT-LEDS, finding a growing number of NDCs and LT-LEDS that address fossil fuel production as part of mitigation. For the first time, several countries incorporate policies and/ or pathways for a managed decline of fossil fuel production. In contrast, many others foresee continued or expanded fossil fuel production, with no mention of efforts to prepare for a transition. Opportunities remain for countries to make better use of NDCs and LT-LEDS to align fossil fuel production with the Paris Agreement, including by more comprehensively reflecting on the equity implications of their plans, as well as addressing how countries plan to diversify their economies, ensure a just transition for workers, and cooperate internationally on a managed wind-down of fossil fuel supply. As COP26 approaches, this window of opportunity is still open, but it is rapidly closing.

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Dupont, Mathieu. NDCS Group Meeting Work overview: NCSP Task ORNL IP&D-5 [Slides]. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1908172.

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Pruett, Duncan, and Christina Hill. Climate Plans for the People: Civil society and community participation in national action plans on climate change. Oxfam International, 2024. http://dx.doi.org/10.21201/2024.000019.

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In 2024, all countries will be updating and submitting their Nationally Determined Contributions (NDCs). These national climate plans outline commitments towards tackling climate change. These plans impact all walks of life and must therefore be inclusive of the whole of society. By examining recent practices across 11 countries, Oxfam found that NDCs were not sufficiently inclusive, often failing to involve civil society and communities who bear the burden of climate change and the impact of climate transition plans. This paper explores who the main actors are in NDCs, which stakeholders have not been included, and why. In order to foster a sustainable, equitable, and inclusive social, economic, and political environment for climate action, the paper makes recommendations for the UN, governments, donors, international agencies and civil society.

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Serra, Lucila, Diana Smallridge, Barbara Buchner, José Juan Gomes Lorenzo, Chiara Trabacchi, and Maria Netto. The Role of National Development Banks in Intermediating International Climate Finance to Scale Up Private Sector Investments. Inter-American Development Bank, 2012. http://dx.doi.org/10.18235/0006938.

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Significant investments are needed to support the global transition to a low-carbon, climate resilient future. Current finance flows fall short of global financing needs, and massive scaling up is needed to unlock additional financial resources and foster a sustainable investment pathway. Overcoming barriers to private sector investments is critical, and international climate finance can play a catalytic role in this regard. National development banks (NDBs) have a unique role in this context, both complementing and catalyzing private sector players. NDBs have a privileged position in their local markets, strong knowledge of and long-standing relationships with the local private sector, a good understanding of local barriers to investment, and opportunities and vast experience in long-term investment financing. This paper discusses the unique role that NDBs could play in scaling up private financing for climate change mitigation projects through the intermediation of international and national public climate finance in their respective local credit markets and the conditions that would be needed for them to be most effective. It draws from experiences in international climate finance and best practices, processes, and products of NDBs within the Latin American and Caribbean region.

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Luomi, Mari, Thamir Alshehri, and Fatih Yilmaz. The Gulf Cooperation Council and the Circular Carbon Economy: Progress and Potential. King Abdullah Petroleum Studies and Research Center, 2022. http://dx.doi.org/10.30573/ks--2022-dp06.

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Over the past year, all six Gulf Cooperation Council (GCC) countries have updated their medium-term greenhouse gas (GHG) emission targets by submitting revised nationally determined contributions (NDCs) under the Paris Agreement. Bahrain, Saudi Arabia, the United Arab Emirates (UAE), and Saudi Aramco have also announced net-zero emission targets. Work is now beginning to develop more detailed roadmaps and implementation plans, some elements of which are already laid out in the updated NDCs.

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