Einloggen

Thematische Bibliographien / N - Aryl Y - Lactam / Dissertationen

Um die anderen Arten von Veröffentlichungen zu diesem Thema anzuzeigen, folgen Sie diesem Link: N - Aryl Y - Lactam.

Dissertationen zum Thema „N - Aryl Y - Lactam“

Autor: Grafiati

Veröffentlicht am 18. Mai 2024

Geben Sie eine Quelle nach APA, MLA, Chicago, Harvard und anderen Zitierweisen an

Wählen Sie eine Art der Quelle aus:

Machen Sie sich mit Top-50 Dissertationen für die Forschung zum Thema "N - Aryl Y - Lactam" bekannt.

Neben jedem Werk im Literaturverzeichnis ist die Option "Zur Bibliographie hinzufügen" verfügbar. Nutzen Sie sie, wird Ihre bibliographische Angabe des gewählten Werkes nach der nötigen Zitierweise (APA, MLA, Harvard, Chicago, Vancouver usw.) automatisch gestaltet.

Sie können auch den vollen Text der wissenschaftlichen Publikation im PDF-Format herunterladen und eine Online-Annotation der Arbeit lesen, wenn die relevanten Parameter in den Metadaten verfügbar sind.

Sehen Sie die Dissertationen für verschiedene Spezialgebieten durch und erstellen Sie Ihre Bibliographie auf korrekte Weise.

1

Barman, Gopa. "Synthetic studies on N - Aryl Y - Lactam & N - Aryl Y - Thio - Lactam : chemoselective Transformation to N-Aryl-Pyrrolidine, N-Aryl Succinimide and Other Bioactive Compounds." Thesis, University of North Bengal, 2009. http://hdl.handle.net/123456789/1379.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

2

Bhattacharya, Biplob. "Synthesis and Anti-MRSA Activity of Hydrophilic C3-Acylated N-Thiolated β-Lactams and N-Acyl Ciprofloxacin-N-Thiolated β-Lactam Hybrids". Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4289.

Der volle Inhalt der Quelle

Annotation:

The Turos laboratory has been working with N-thiolated β-lactams for years trying to understand the mode of action and structural features it needs to have biological activity. Over the years new data has shown promising inhibitory activity against various microbes. In this dissertation, a review of the vast amount of work carried out on N-thiolated β-lactams in Turos laboratory has been done and their novelty, in terms of structure and mechanism has been discussed. A complete outline of our work in the discovery and ongoing development of these compounds, starting from our initial, unexpected

APA, Harvard, Vancouver, ISO und andere Zitierweisen

3

Bekdemir, Yunus. "The mechanisms of hydrolysis and protonation behaviour of N-aryl sultams." Thesis, University of Essex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.387004.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

4

Dyke, Alan. "Novel Câ‚‚-symmetric N,N-donor ligands and the anionic thia-Fries rearrangement of aryl triflates." Thesis, University of Bristol, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404435.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

5

Yasui, Hiroto. "Studies on Addition to 1-Aryl-1-alkynes and N-Alkynyl Amides." 京都大学 (Kyoto University), 2008. http://hdl.handle.net/2433/57271.

Der volle Inhalt der Quelle

Annotation:

Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(工学)<br>甲第13827号<br>工博第2931号<br>新制||工||1433(附属図書館)<br>26043<br>UT51-2008-C743<br>京都大学大学院工学研究科材料化学専攻<br>(主査)教授大嶌幸一郎, 教授檜山爲次郎, 教授松原誠二郎<br>学位規則第4条第1項該当

APA, Harvard, Vancouver, ISO und andere Zitierweisen

6

Mori, Shigeki. "Studies on metallation of meso-aryl substituted hexaphyrins and N-fused pentaphyrins." 京都大学 (Kyoto University), 2008. http://hdl.handle.net/2433/136922.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

7

Baeza, Mario Ivan. "Synthesis and characterization of acetylenic derivatives of the actinide extractant (aryl)-N,N-di-(alkyl)carbamoylmethylphosphine oxide (CMPO)." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

8

Prosen, Katherine Rose. "Investigating the Mode of Action of a Novel N-sec-butylthiolated Beta-lactam Against Staphylococcus aureus." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3609.

Der volle Inhalt der Quelle

Annotation:

N-sec -butylthioloated β-lactam (NsβL) is a novel beta-lactam antimicrobial with a mechanism of action proposed to inhibit 3-oxoacyl-acyl carrier protein synthase (ACP) III (FabH), resulting in the inhibition of fatty acid synthesis. It has been suggested that NsβL inhibits FabH indirectly by inactivating coenzyme-A (CoA). CoA is an essential cofactor for numerous proteins involved in glycolysis, the citric acid cycle (TCA), and pyruvate metabolism, in addition to fatty acid biosynthesis. This study aimed to determine the effects of NsβL on a diverse array of laboratory and clinical Staphyloc

APA, Harvard, Vancouver, ISO und andere Zitierweisen

9

Cui, Xiuhua. "Asymmetric hydrogenations of aryl alkenes using imidazol-2-ylidene iridium complexes." Texas A&M University, 2005. http://hdl.handle.net/1969.1/2456.

Der volle Inhalt der Quelle

Annotation:

A library of iridium complexes featuring oxazoline and imidazol-2-ylidene ligands were synthesized by reaction of a library of imidazoles with a second library of oxazoline iodides. These complexes were active catalysts for hydrogenations of aryl substituted monoenes. Tri- and 1,1-disubstituted alkenes were hydrogenated quantitatively with ee??s up to 99% at 1 atm hydrogen pressure. Catalyst, substrate, temperature and pressure effects were studied. The iridium complexes were also used for the kinetic study of hydrogenation of 2,3- diphenylbutadiene. This hydrogenation is a stepwise reaction:

APA, Harvard, Vancouver, ISO und andere Zitierweisen

10

Jiao, Dezhi. "Alkyl and aryl imidazolium salts in aqueous supramolecular systems with cucurbit[n]uril." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610692.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

11

Zajdel, Pawel. "Novel Aryl-alkyl-piperazines with N-acylated amino acids as serotoninergic receptors ligands." Montpellier 1, 2006. http://www.theses.fr/2006MON13511.

Der volle Inhalt der Quelle

Annotation:

Ce travail présente des nouveaux composés ciblant les récepteurs sérotoninergiques. La première partie traite de la synthèse supposée d'une chimiothèque d'arylpiperazines. Plusieurs composés montrent une haute affinité pour 5-HT1A(K1=3-52nM). Des tests pharmacologiques pré-cliniques ont révélé des comportements de type agoniste complet ou partiel de 5-HT1A ou antagoniste 5-HT1A/5-HT2A. La synthèse supportée de 64 dérivés sulfonamide de la proline carboxamide est décrite, visant l'obtention d'antagonistes de 5-HT7. La dernière partie traite de la synthèse supportée sur lanternes BAL de dérivés

APA, Harvard, Vancouver, ISO und andere Zitierweisen

12

Wang, Yue-Ting. "Detection of reactive intermediates from quinol esters and O-aryl-N-methanesulfonyl hydroxylamine." Miami University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1249001098.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

13

Mtongana, Sibusiso. "A multinuclear magnetic resonance spectroscopy study of E/Z configurational isomers of unsymmetrical N-alkyl-N-alkyl(aryl)-N'-acylthioureas of platinum(II) complexes." Thesis, Stellenbosch : Stellenbosch University, 2006. http://hdl.handle.net/10019.1/21893.

Der volle Inhalt der Quelle

Annotation:

Dissertation (PhD)--University of Stellenbosch, 2006.<br>ENGLISH ABSTRACT: The partial double bond character of the carbon-nitrogen bond of the (S)C-NRR’ moiety results in unsymmetrical dialkyl-substituted N-alkyl-N-alkyl(aryl)-N’-acylthioureas, R”C(O)NHC(S)NRR’ (HL) displaying E,Z configurational isomerism in solution. The isomerism manifests itself by the duplication of resonances of the N-alkyl groups in the 1H and 13C NMR spectra. In one class of these ligands where R and R’ groups are non-equivalent alkyl groups the isomerism is easily observable at 298 K in chloroform. In the other c

APA, Harvard, Vancouver, ISO und andere Zitierweisen

14

Bruce, Jocelyn Catherine. "Use of the N,N-dialkyl-N’-benzoyl(thio)selenoureas as single source precursors for the synthesis of semiconducting quantum dots." Thesis, Stellenbosch : Stellenbosch University, 2008. http://hdl.handle.net/10019.1/1205.

Der volle Inhalt der Quelle

Annotation:

Thesis (PhD (Chemistry and Polymer Science))--Stellenbosch University, 2008.<br>The successful preparation and structural characterization of a number of N,N-dialkyl-N’-benzoyl(thio)selenourea ligands is described; where the intermolecular interactions are characterized by the presence of Resonance Assisted Hydrogen Bonding (RAHB), π- π interactions between neighbouring benzene residues only being evident amongst the longer alkyl chain derivatives. The first structural characterization of an asymmetrically substituted N,N-dialkyl- N’-benzoylselenourea ligand reveals an increased stability

APA, Harvard, Vancouver, ISO und andere Zitierweisen

15

Axelsson, Linda. "Development of HIV-1 Protease Inhibitors and Palladium-Catalyzed Synthesis of Aryl Ketones and N-Allylbenzamides." Doctoral thesis, Uppsala universitet, Institutionen för läkemedelskemi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-211672.

Der volle Inhalt der Quelle

Annotation:

The use of palladium-catalyzed reactions to introduce new carbon-carbon bonds is a fundamental synthetic strategy that has been widely embraced due to its high chemo- and regioselectivity and functional group tolerance. In this context, Pd(0)-catalyzed aminocarbonylations using Mo(CO)6 instead of toxic and gaseous CO and with allylamine as the nucleophile were investigated. The aminocarbonylated product dominated over the Mizoroki-Heck product, and (hetero)aryl iodides, bromides and chlorides gave N-allylbenzamides in good yields. In this thesis improvements to an existing protocol for the Pd(

APA, Harvard, Vancouver, ISO und andere Zitierweisen

16

El-Hassan, Inas. "Synthèse de N-aryl-C, C-dialkoxycarbonylnitrones et étude par RPE de leur conversion en nitroxydes." Aix-Marseille 1, 2006. http://www.theses.fr/2006AIX11033.

Der volle Inhalt der Quelle

Annotation:

La première partie de ce mémoire décrit la synthèse d'une série de sept N-Aryl-C,C-dialkoxycarbonylnitrones (1-7), par condensation d'un carbanion dérivé du bromomalonate d'éthyle ou de méthyle sur un composé nitroso approprié. Les rendements en cétonitrones varient de 25 % à 85 %, en fonction de la nature du groupement aryle. La seconde partie concerne la conversion des cétonitrones 1-7 en nitroxydes selon trois mécanismes : le piégeage de radicaux, la réaction de Forrester-hepburn et le piégeage de SPIN inversé. Ces cétonitrones sont toutes de très bons pièges des radicaux carbones, mais son

APA, Harvard, Vancouver, ISO und andere Zitierweisen

17

Chopra, Karishma. "Improved Cryopreservation of Induced Pluripotent Stem Cells Using N-aryl Glycosidic Small Molecule Ice Recrystallization Inhibitors." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42323.

Der volle Inhalt der Quelle

Annotation:

Induced pluripotent stem cells (iPSCs) are an attractive cell source for various applications in regenerative medicine and cell-based therapies given their unique capability to differentiate into any cell type of the human body. However, human iPSCs are highly vulnerable to cryopreservation with post-thaw survival rates of 40-60%; this is due to cryoinjury resulting from ice recrystallization when using conventional slow cooling protocols. Ice recrystallization is a process where the growth of large ice crystals occurs at the expense of small ice crystals. Ice recrystallization inhibitors (I

APA, Harvard, Vancouver, ISO und andere Zitierweisen

18

Delgado, Justine Lane. "Design, synthesis, and evaluation of N-1 Aryl fluoroquinolones for the development of human topoisomerase inhibitors." Diss., University of Iowa, 2018. https://ir.uiowa.edu/etd/6564.

Der volle Inhalt der Quelle

Annotation:

DNA topoisomerases are responsible for managing the topology of DNA and play critical roles in many biological processes involving DNA. DNA topoisomerases are known therapeutic targets of several successful anticancer chemotherapeutics. Most clinically used topoisomerase-targeting anticancer drugs convert the enzyme into a cellular poison by trapping a covalent topoisomerase-DNA catalytic intermediate as a topoisomerase-drug-DNA ternary complex. Formation of ternary complex leads to cytotoxic events, such as inhibition of DNA replication, DNA strand breaks, and ultimately cell death. This mode

APA, Harvard, Vancouver, ISO und andere Zitierweisen

19

Aquino, Estefania da Costa. "Síntese de 3-Trifluoracetil-1H-pirróis N-Aril Substituídos." Universidade Federal de Santa Maria, 2011. http://repositorio.ufsm.br/handle/1/10481.

Der volle Inhalt der Quelle

Annotation:

Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>This work presents a new, simple and versatile strategy for the synthesis of new N-aryl substituted 3-trifluoroacetyl-1H-pyrroles. The pyrroles were obtained by the reaction of 3-trifluoroacetyl-4,5-dihydrofuran with aryl amines of general formula ArNH2, and Ar= C6H4, 2-MeO(C6H4), 3-MeO(C6H4), 4-MeO(C6H4), 2-Me(C6H4), 3-Me(C6H4), 4-Me(C6H4), 3-F(C6H4), 4-F(C6H4), 3-Cl(C6H4), 4-Cl(C6H4), 4-OH(C6H4), 2-OH-5-Me(C6H3), 3-OH-4-Me(C6H3), 4-Br(C6H4) generating 1,1,1-trifluoro-3-(2-hydroxyethyl)-4-arylamino-3-beten-2-ones intermediates t

APA, Harvard, Vancouver, ISO und andere Zitierweisen

20

Esposito, Oriana. "Mechanistic and kinetic studies on aryl and alkyl amination reaction catalysed by palladium n-heterocyclic carbene complexes." Thesis, University of Sussex, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487117.

Der volle Inhalt der Quelle

Annotation:

Several studies have been carried out to establish the sequence of intermediates in the catalytic cycle for amination of aryl halides. I ,2 The mechanism suggested by Cloke and Caddick group for the catalytic amination of aryl chloride employing [Pd(NRC)2l as precatalyst (NRC = Ã‚Â·N-heterocyclic carbene), proposed a neutral, 12-electrons mono-ligated Pd(NHC) species as the active intermediate.3 The isolation of a series of (ItBu)2Pd(R-aryl)chloride complexes (ltBu = 1,3-di-tert-butylimidazol-2-ylidene) allowed for kinetic studies hence leading to a mechanistic understanding of the I oxidative

APA, Harvard, Vancouver, ISO und andere Zitierweisen

21

Ng, Fei-yeung, and 吳飛洋. "Structure and properties of self-assembled coordination compounds: homoleptic d10-metal aryl/alkylacetylides, ruthenium n-heterocyclesand picolinates." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B37878566.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

22

Mayoka, Godfrey Wabwile. "Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles". Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29825.

Der volle Inhalt der Quelle

Annotation:

Malaria and schistosomiasis represent the two most prevalent parasitic infections with grievous repercussions on the socio-economic development of affected countries, mainly in sub-Saharan Africa and South-East Asia. Despite their ravaging effects, the treatments of these two diseases have been committed to a limited arsenal of drugs that are threatened by resistance. This scenario, therefore, calls for decisive steps being taken towards the discovery and development of novel drugs with the ability to target multiple parasite stages and be efficacious against resistant parasite strains to achi

APA, Harvard, Vancouver, ISO und andere Zitierweisen

23

Hartsel, Joshua Alan. "Revisiting aryl N-methylcarbamate acetylcholinesterase inhibitors as potential insecticides to combat the malaria-transmitting mosquito, Anopheles gambiae." Diss., Virginia Tech, 2011. http://hdl.handle.net/10919/73002.

Der volle Inhalt der Quelle

Annotation:

My graduate work focused on the syntheses and pharmacology of species-selective aryl methylcarbamate acetylcholinesterase inhibitors to combat the malaria-transmitting mosquito, Anopheles gambiae. We identified six novel carbamates that demonstrated levels of target selectivity exceeding our project milestone of 100-fold. Among the C2-substituted phenylcarbamates examined (class II), 2'-(2- ethylbutoxy)phenyl N-methylcarbamate (9bd*) was extraordinarily selective (570-fold + 72). The high level of selectivity observed for many of the class II carbamates was attributed to a helical displacement

APA, Harvard, Vancouver, ISO und andere Zitierweisen

24

Odabas, Serhat. "Asymmetric Synthesis Of N-aryl Substituted Chiral 1,4-amino Alcohol Derivatives And Applications In Various Asymmetric Transformation Reactions." Master's thesis, METU, 2007. http://etd.lib.metu.edu.tr/upload/12608489/index.pdf.

Der volle Inhalt der Quelle

Annotation:

The asymmetric synthesis of N-aryl substituted chiral 1,4-aminoalcohols and their applications in asymmetric borane reduction and enantioselective diethylzinc addition to benzaldehyde reactions were performed starting from meso anhydride 51 that is the cycloadduct of cyclopentadiene and maleic anhydride. The desymmetrization of meso-anhydride 51 was achieved by using quinine or quinidine with very high enantiomeric excess value (up to 98% ee) and with high chemicalb yield. The quinine-mediated desymmetrization of meso-anhydride 51 with methanol gave (2S,3R)-(-)-cis-monoester 52. The hemiester

APA, Harvard, Vancouver, ISO und andere Zitierweisen

25

Ng, Fei-yeung. "Structure and properties of self-assembled coordination compounds : homoleptic d10-metal aryl/alkylacetylides, ruthenium n-heterocycles and picolinates." View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36587126.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

26

Iqbal, Aman. "Studies on an N-terminal nucleophile hydrolase and enzymes of clavulanic acid biosynthesis." Thesis, University of Oxford, 2008. http://ora.ox.ac.uk/objects/uuid:5ae868c0-007b-4cb8-b4cf-21ab93f69281.

Der volle Inhalt der Quelle

Annotation:

(3R,5R)-Clavulanic acid is a clinically important inhibitor of Class A β-lactamases. Progress has been made in to establishing the steps of clavulanic acid biosynthesis leading to (3S,5S)-clavaminic acid. However, the mechanism by which (3S,5S)-clavaminic acid is converted to the penultimate intermediate (3R,5R)-clavaldehyde remains elusive. It is believed that the products of the later genes (orf10-orf18) of the clavulanic acid biosynthesis gene cluster are probably involved in this conversion. Part I of this thesis describes biochemical and structural studies carried out on OAT2, a memb

APA, Harvard, Vancouver, ISO und andere Zitierweisen

27

Harrelson, John P. "A comparative study of cytochromes P450 2E1 and 2A6 : substrate dynamics, multiple ligand binding, and adduct formatioin by N-acetyl-m-aminophenol /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/8166.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

28

Bob-Egbe, Opetoritse. "Development of axially chiral 2-aryl-4-dialkylaminopyridine-N-oxide based catalysts for the sulfonylative kinetic resolution of amines." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9776.

Der volle Inhalt der Quelle

Annotation:

Lewis base catalysis has been studied extensively in recent years as a powerful tool for introducing asymmetry into a variety of reactions, avoiding the use of expensive and potentially toxic metal catalysts. There is however still ample scope for the development of procedures for the non-enzymatic catalytic kinetic resolution (KR) of amines. Unlike alcohols, the intrinsic high reactivity of amines towards acyl and sulfonyl donors makes their KR highly challenging. As a result, there are relatively few publications on non-enzymatic catalytic KR of amines via acylation1-8 and none via sulfonyla

APA, Harvard, Vancouver, ISO und andere Zitierweisen

29

Balkenhohl, Moritz [Verfasser], and Paul [Akademischer Betreuer] Knochel. "Metalation and amination of N-heterocycles and the halogen/zinc exchange of aryl halides / Moritz Balkenhohl ; Betreuer: Paul Knochel." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1211957128/34.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

30

Leslie, J. Michelle. "N-Thiolated b-lactam antibiotics : synthesis and structure-activity studies of C3 oxygenated derivatives and attachement to new, functionalized caprolactone monomers and polymers." [Tampa, Fla] : University of South Florida, 2006. http://purl.fcla.edu/usf/dc/et/SFE0001685.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

31

Meckle, Manuel [Verfasser]. "Synthesis and properties of fully conjugated cyclo[n]thiophenes and investigation into a boron-templated aryl-coupling method / Manuel Meckle." Ulm : Universität Ulm, 2016. http://d-nb.info/1103052330/34.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

32

Belot, Vincent. "Accès à une bibliothèque ciblée de n-aryl-thiazoline-2-thiones pour l'établissement d'une nouvelle échelle de taille de substituants usuels." Thesis, Aix-Marseille, 2017. http://www.theses.fr/2017AIXM0408/document.

Der volle Inhalt der Quelle

Annotation:

Une échelle de taille contenant 20 substituants usuels en chimie a été construite à partir des barrières de rotations de N-aryl-thiazoline-2-thiones. L’énergie d’activation ΔG≠rot qui est mesurée reflète l’encombrement stérique du substituant en ortho du cycle benzénique. Les perturbations électroniques, et les facteurs externes tels que la température ou le solvant sont négligeables. La grande sensibilité du modèle proposé conduit au classement suivant Me > Cl et CN > OMe > OH. Ces classements divergents décrits dans la littérature seront discutés. Une limitation du modèle proposé co

APA, Harvard, Vancouver, ISO und andere Zitierweisen

33

Pialat, Amélie. "Formation de liaisons C-N et C-O par catalyse de coordination ou par oxydation à l'iode hypervalent." Thesis, Montpellier 2, 2013. http://www.theses.fr/2013MON20204/document.

Der volle Inhalt der Quelle

Annotation:

La fonctionnalisation directe de liaisons C-H offre une alternative plus économe en atomes et étapes que les traditionnelles méthodes de synthèse basées sur la transformation de molécules pré fonctionnalisées. Ainsi, les réactions d'amination intermoléculaire de liaisons C(sp3)-H avec des nitrènoïdes sont généralement effectuées avec des rendements et des régiosélectivités modérés et utilisent pour cela des catalyseurs coûteux. Dans ce contexte, nous avons créé de nouveaux systèmes bifonctionnels pour la formation de liaisons C-N aliphatiques catalysée par le cuivre et l'argent. Ces systèmes s

APA, Harvard, Vancouver, ISO und andere Zitierweisen

34

Würtz, Sebastian. "Palladium-Katalyse Synthese und Anwendung neuartiger chiraler und achiraler N-heterocyclischer Carbene (NHC) in Palladium-katalysierten Kreuzkupplungen und Palladium-katalysierte oxidative Cyclisierung von N-Aryl-Enaminen zur Synthese hochfunktionalisierter Indole." Lichtenberg (Odw.) Harland Media, 2008. http://d-nb.info/992466458/04.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

35

Whipp, Christopher J. "Part 1: The Direct Arylation of Azine N-Oxides with Aryl Triflates Part 2: The Site-Selective Direct Arylation of Substituted Indoles." Thesis, University of Ottawa (Canada), 2010. http://hdl.handle.net/10393/28792.

Der volle Inhalt der Quelle

Annotation:

Part 1: The Direct Arylation of Azine N -Oxides with Aryl Triflates. Two sets of conditions for the palladium-catalyzed direct arylation of azine N-oxides with aryl triflates have been developed. Using palladium(II) acetate, a trialkylphosphine ligand, a carbonate base and pivalic acid, both mono- and diarylated azine N-oxides could be synthesized in good to excellent yields.* The reaction regioselectivity was examined for 3-substituted pyridine N-oxides, with arylation at C2 being favoured. The methodology was applied to the efficient formal synthesis of a biologically active diaryl pyridin

APA, Harvard, Vancouver, ISO und andere Zitierweisen

36

May, Tricia Lee. "Copper-Based N-Heterocyclic Carbene Complexes for Catalytic Enantioselective Conjugate Additions of Alkyl-, Aryl- and Vinyl-Based Nucleophiles to Form All-Carbon Quaternary Stereogenic Centers." Thesis, Boston College, 2011. http://hdl.handle.net/2345/2650.

Der volle Inhalt der Quelle

Annotation:

Thesis advisor: Amir H. Hoveyda<br>Chapter 1 Enantioselective Conjugate Additions of Carbon Nucleophiles to Activated Olefins: Preparation of Enantioenriched Compounds Containing All-Carbon Quaternary Stereogenic Centers. Methods for enantioselective conjugate addition of nucleophiles to activated olefins generating products containing all-carbon quaternary stereogenic centers are critically reviewed. Enantioselective conjugate addition has been shown to be a powerful and concise approach to construct carbon-carbon bonds to prepare compounds containing sterically hindered stereogenic centers a

APA, Harvard, Vancouver, ISO und andere Zitierweisen

37

Cromer, Rémy. "Porphyrines n-substituees : modelisation de l'inhibition d'hemoproteines." Université Louis Pasteur (Strasbourg) (1971-2008), 1986. http://www.theses.fr/1986STR13015.

Der volle Inhalt der Quelle

Annotation:

Migration cobalt-azote des groupements : phenyl et styryl. L'etude des reactions de migration dans les porphyrines de cobalt(iii) aryliques a justifie l'utilisation de ces dernieres pour modeliser l'hydrazinolyse des hemoproteines. Les porphyrines de cobalt(iii) aryliques ont un comportement analogue a celui des porphyrines de fer(iii) aryliques. Oxydation des styryl -co(iii) porphyrines. Mecanisme de reaction. Extension de cette reaction a la cyclisation en serie arylique qui permet la synthese de la premiere porphyrine n,n'-(phenylene-1,2) analogue du produit d'inhibition suicide obtenu apre

APA, Harvard, Vancouver, ISO und andere Zitierweisen

38

Svensson, Akusjärvi Emma [Verfasser]. "Mechanistic Investigations of the Direct Arylation of Pyridine N-oxides with Bromoarenes and Structure-Reactivity Relationship of Aryl Palladium Complexes in Transmetalations with Organoboron Compounds / Emma Svensson Akusjärvi." Berlin : Freie Universität Berlin, 2018. http://d-nb.info/1176635034/34.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

39

Platon, Mélanie. "Propriétés et performances de phosphines ferrocéniques dans le couplage C-O, C-S et C-N : nouvelles méthodologies de synthèse au palladium." Phd thesis, Université de Bourgogne, 2012. http://tel.archives-ouvertes.fr/tel-00818998.

Der volle Inhalt der Quelle

Annotation:

Les ligands multidentes montrent généralement de très bonnes activités dans la catalyse organométallique au palladium à faibles charges. Parmi ces ligands, l'utilisation des ligands polyphosphines ferrocéniques mènent à des résultats intéressants. Des systèmes catalytiques palladium/triphosphine ferrocénique robustes ont permis d'obtenir d'une part des diarylamines et d'autre part des éthers d'aryle et d'hétéroaryle avec de faibles charges catalytiques. Des calculs théoriques de DFT sur le cycle catalytique lors de la formation d'éthers d'aryle et d'hétéroaryle ont été réalisés. La présence d'

APA, Harvard, Vancouver, ISO und andere Zitierweisen

40

Delamare, Madeleine. "Nouvelles voies de synthèse d'hétérocycles polyazanaphtalènes en vue de leur application en pharmacie, en agro-industrie et en phytochimie." Rouen, 1998. http://www.theses.fr/1998ROUES024.

Der volle Inhalt der Quelle

Annotation:

L'activité de produits imidazolés vis-à-vis de l'inhibition de la farnésyl transférase a conduit au développement d'un programme de recherche industriel ayant pour base d'une part un azole et d'autre part un hétérocycle permettant une reconnaissance enzymatique spécifique. Dans le cadre de ce programme, nous nous sommes intéressés aux synthèses de divers hétérocycles de structures polyazanaphtalènes. Ainsi, des 6-acylisoquinol-1(2H)-ones, des 6- et 7-formyl-1,8-naphtyridin-2-ones et des 6- et 7-formyl-1,5-naphtyridin-2-ones, pouvant être substituées en position 3 par un groupe méthyle et en po

APA, Harvard, Vancouver, ISO und andere Zitierweisen

41

Kerbal, Abdelali. "Cycloaddition de diarylnitrilimines et d'azides sur diverses énones et énamines dérivées d'indadones et de tétralones : Regiochimie, diasteréochimie et transformation des cycloadduits." Besançon, 1988. http://www.theses.fr/1988BESA2038.

Der volle Inhalt der Quelle

Annotation:

La cycloaddition dipolaire-1,3 des diarylnitrilimines sur diverses enones a double-liaison dipolarophile juxtacyclique est regiospecifique. Lorsque le dipolarophile présente deux faces diastereotopiques, l'approche dipole-dipolarographie se fait du côté le moins encombré : - de façon diastereospecifique sur les enones dérivées de l'indanone-1 substituée ou de la tetralone-1 substituée lorsque ces dernières portent en -3 ou -4 un substituant occupant une position axiale - de facon diastereoselective sur les enones dérivées de la tetralone-1 portant un substituant en -4 qui peut adopter une disp

APA, Harvard, Vancouver, ISO und andere Zitierweisen

42

Ibn, Ahmed Saïd. "Une approche à la synthèse enantiospecifique d'alcaloïdes du narcisse." Nancy 1, 1988. http://www.theses.fr/1988NAN10150.

Der volle Inhalt der Quelle

Annotation:

Approche de la synthèse d'alcaloïdes derivés de dioxolo-1,3 (4,5-J) phénanthridine : la première partie traite de quelques analogues non cyclisés (synthèse et étude de l'activité anticancéreuse) ; la deuxième partie résume les différents essais de synthèse totale de ces alcaloïdes et particulièrement de l'O-acétyl-2 DI-O-benzyl-3,4 désoxo lycoricidine

APA, Harvard, Vancouver, ISO und andere Zitierweisen

43

Chao, Hsin-Chi, and 趙星智. "Preparation of N-aryl Aziridines." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/57550471258830594389.

Der volle Inhalt der Quelle

Annotation:

碩士<br>中原大學<br>化學研究所<br>100<br>Aziridine, a high-application value compounds, not only widely used in organic synthesis reactions but also in the synthesis of natural products and medicine often have the structure of the aziridine.In recent years,many chemists put into the reserch because of the aziridine with the anti-tumor biological activity. 　　In this paper, we used a series of aryl azide mix in electron- withdrawing alkenes, under high temperature and solvent environment, prepared a series of corresponding phenyl- substituted nitrogen base aziridine. 　　The characteristics of this experimen

APA, Harvard, Vancouver, ISO und andere Zitierweisen

44

Lai, Huei-Jia, and 賴慧嘉. "Synthesis and Spectroscopic Study of N-(4-aryl)-5-methylisoxazol-4-carboxamide and N-(4-aryl)-3-methylisoxazol-4-carboxamide." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/40426157355462648267.

Der volle Inhalt der Quelle

Annotation:

碩士<br>亞洲大學<br>生物科技學系碩士班<br>98<br>Isoxazole is a class of heterocyclic compounds having a remarkable number of applications and has been demonstrated to be very versatile building blocks in organic synthesis. Two series of N-(4-aryl)-5-methylisoxazol-4-carboxamide and N-(4-aryl)-3-methylisoxazol-4-carboxamide were synthesized and spectroscopic studied to investigate the variation reaction on the substutents phenyl ring. The isoxazole derivatives were prepared from the reaction 5-methylisoxazole-4-carbonyl chloride or 3-methylisoxazole-4-carbonyl chloride and substituted anilines in good yields

APA, Harvard, Vancouver, ISO und andere Zitierweisen

45

Lesenyeho, Lehlogonolo Godfrey. "Palladium-catalyzed heteroannulation of 2-ARYL- 3-IODO-4-(Phenylamino)quinolines and 4-(N,N-allylphenylamino)-2-ARYL-3-iodoquinolines." Diss., 2010. http://hdl.handle.net/10500/3970.

Der volle Inhalt der Quelle

Annotation:

The previously described 2-aryl-4-chloro-3-iodoquinolines were prepared following literature procedure and in turn converted to the corresponding hitherto unknown 2-aryl-3-iodo-4-(phenylamino)quinoline derivatives using aniline in refluxing ethanol. These 2-aryl-3-iodo-4-(phenylamino)quinolines were reacted with allybromide in ethanol at room temperature to afford 4-(N,N-allylphenylamino)-2-aryl-3-iodoquinoline derivatives. The 2-aryl-3-iodo-4-(phenylamino)quinoline and 4-(N,N-allylphenylamino)-2-aryl-3-iodoquinoline derivatives were subjected to metal-catalysed carbon-carbon bond formations.

APA, Harvard, Vancouver, ISO und andere Zitierweisen

46

Yi-JieHuang and 黃奕傑. "The Applications of Sulfonyl Radical on The Synthesis of 2-Quinolinones from N-aryl Amides and Quinolines from N-aryl Enamines." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/42836009015597216859.

Der volle Inhalt der Quelle

Annotation:

碩士<br>國立成功大學<br>化學系<br>104<br>Recently, there has been a growing interest in the application of free radical cyclization reactions to the formation of ring systems. Free radical reactions mediated by sulfonyl radicals have been noted by several groups. Free radical of sulfonyl radical can undergo addition reaction with unsaturated bond generate radical intermediate to undergo either 6-membered or 5-membered ring cyclization onto the aromatic ring effectively and provide synthetically useful methods for the syntheses of 2-quinolinones and quinolines. This thesis is divided into two parts：(1) Th

APA, Harvard, Vancouver, ISO und andere Zitierweisen

47

Wang, Wen-Yang, and 王文揚. "I.Aliphatic Hydroxamates Capped with Substituted Aryl Indole as Histone Deacetylase InhibitorsII.Structure Optimization for Ortho-Aryl N-Hydroxycinnamides as HDAC 8 Isoform-Selective Inhibitors against Cancer CellsII.Structure Optimization forOrtho-Aryl N-Hydroxycinnamides as." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/55xw6v.

Der volle Inhalt der Quelle

Annotation:

碩士<br>臺北醫學大學<br>生藥學研究所<br>102<br>Histone deacetylase (HDAC) inhibitors are regarded as a promising therapeutic for treatment of cancer. However, current HDAC inhibitors have some unsatisfactory problems, including limited potency for solid tumors and dose-limiting side effects. This study includes： I. Aliphatic Hydroxamates Capped with Substituted Aryl Indole as Histone Deacetylase Inhibitors against Cancer Cells; II. Structure Optimization for Ortho-Aryl N-Hydroxycinnamides as HDAC8 Isoform-Selective Inhibitors I. Currently, SAHA and Romidepsin both were FDA-approved HDAC inhibitors to treat

APA, Harvard, Vancouver, ISO und andere Zitierweisen

48

Krishnan, P. Santhana Gopala. "Synthesis and characterisation of n-aryl methacrylatoethyl carbamate homopolymers and copolymers." Thesis, 1992. http://localhost:8080/xmlui/handle/12345678/3094.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

49

呂亭宜. "The Palladium-Catalyzed Cross-Coupling Reaction of Aryl- and Alkenylboron Compound with 2-Bromo-N,N-dimethylacetamide." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/41718512342460728665.

Der volle Inhalt der Quelle

Annotation:

碩士<br>國立中正大學<br>化學研究所<br>91<br>α-Arylamides have potential medical and agricultural applications. β,γ-Unsaturated amides are versatile synthetic intermediates. However, few general methods for their preparation have been reported. In view of the limited number of methodologies for the synthesis of a-arylamides and β,γ-unsaturated amides, we have explored the extension of the palladium-catalyzed cross-coupling of aryl- and alkenylboron compound with 2-bromo-N,N- dimethylacetamide. Thus, a-bromoacetamide (1 equiv) was reacted with arylboron compound (1 equiv) in the pre

APA, Harvard, Vancouver, ISO und andere Zitierweisen

50

Kumar, Ajay K. "Synthesis of biologically active heterocycles VIA imines, Aziridines and N-aryl maleimides." Thesis, 2000. http://hdl.handle.net/2009/2250.

Der volle Inhalt der Quelle

APA, Harvard, Vancouver, ISO und andere Zitierweisen

Wir bieten Rabatte auf alle Premium-Pläne für Autoren, deren Werke in thematische Literatursammlungen aufgenommen wurden. Kontaktieren Sie uns, um einen einzigartigen Promo-Code zu erhalten!