Auswahl der wissenschaftlichen Literatur zum Thema „Musculo-tendinous junction“

ABSTRACTClosed rupture of the FDP tendon is rare. However, whenever they occur the most common site of rupture is the tendon-bone insertion, less frequent site is at the musculo-tendinous junction. Midsubstance ruptures are even more unique and are usually due to underlying pathology such as fracture, cystic degeneration, rheumatoid arthritis, or sequel following local steroid injection. This report describes a closed rupture of FDP tendon of little finger. Mechanism of injury, diagnosis and management are discussed.

The aetiology, management, and results of acute rupture of primary flexor tendon repairs in Zones I and II of the fingers in children have not been previously investigated. The author reports on a personal series of 10 children treated over a period of 13 years. The aetiology is different when compared with adults: children less than 5 years of age usually rupture their primary repairs whilst the hand is completely immobilized in a cast; whereas teenagers usually rupture their tendons when falling down while playing. In the current series, direct re-repair was performed without lengthening at the musculo-tendinous junction, and no free tendon grafts were used. The results were worse than other paediatric series of primary flexor tendon repairs. Using the Strickland-Glogovac criteria, there was only one excellent outcome, the remaining nine being either a good ( n = 5) or fair ( n = 4) outcome.

Twenty female animals selected for study from which 60% buffaloes and 40% cattle with a mean age of 6.32 ± 0.66 years. The mean duration of illness was 20.7 ± 2.13 days and majority recently calved (45%). Mean rectal temperature, respiratory and heart rates elevated and rumen motility decreased. Ferroscopy was positive in fifteen animals. Haematological and Biochemical parameters revealed leucocytosis, neutrophilia and lymphocytopenia, decreased albumin and increased total plasma proteins, globulin, AST, ALT, serum creatinine, blood urea nitrogen and plasma fibrinogen level. Laparorumenotomy revealed adhesion of reticulum and left abdominal wall in seven, reticulum and right abdominal wall in three, reticulum and ventral abdominal wall in one and reticulum with diaphragm in four cases with non-metallic foreign bodies and frothy rumen content in five animals. Ruminitis, sloughing and haemorrhages of ruminal papillae in two cases. Complications like recurrent tympany, subcutaneous emphysema, swelling and discharge at surgical site were managed appropriately and all animals recovered. In-vitro ultrasonographic examination of diaphragm revealed that the right lower half musculo-tendinous junction of diaphragm was thinner than the left lower half musculo-tendinous junction of diaphragm.

Introduction: Post-surgical knee stiffness is a debilitating complication and its treatment ranges from simple arthroscopic adhesiolysis to more extensive Quadricepsplasty. Physiotherapy rarely sufces in most cases. We are presenting a case of surgically intervened pigmented villonodular synovitis (PVNS) with stiff knee treated by open intraarticular adhesiolysis and a modied V-Y quadricepsplasty and extensor mechanism release, a rst of its kind. An Indian male in his 20s, a surgically intervened case Case Presentation: of PVNS lost to follow-up due to COVID-19 Lockdown presented with a stiff knee with movement of 0-30o exion in early 2022. An open adhesiolysis of the joint arthrobrosis using the previous incision was performed, and a separate full thickness V-shaped incision at proximal Musculo-tendinous junction of quadriceps tendon was given to achieve exion of 130°.The tendon was repaired in its lengthened position, giving the appearance of a V to Y. Post-operatively, muscles strengthening, and Range of motion (ROM) exercises including continuous passive motion (CPM), were included following a specic physiotherapy protocol immediately after surgery. 10 weeks post-op, the patient has 0-120° active and passive ROM of the knee with an extensor lag of 7°. A planned and proper surgical approach targeting the primary cause of sti Conclusion: ffness augmented with direct extensor mechanism lengthening procedures (quadricepsplasty) if needed, can achieve good per-operative knee ROM. Aggressive surgery specic postoperative physiotherapy and rehabilitation play a major role in achieving satisfactory results

La regénération limitée du tendon et sa forte sollicitation mécanique font de sa réparation un défi clinique. Contrairement au tendon, la jonction myo-tendineuse nourrit peu de recherche. Sa reconstruction remplit la difficile tâche de joindre le tendon, rigide, au muscle plus mou. L’utilisation de gradients produits par deux techniques différentes a été choisie pour produire une jonction résistante et étudier l’intéraction cellule-matrice. La première technique permet l’obtention de matrices macroporeuses de collagène I par fibrillogenèse topotactique après congélation contrôlée. Ces matrices anisotropes micro-structurées présentent des propriétés mécaniques en condition humide inégalées dans la littérature, et permettent la colonisation et l’alignement spontané de fibroblastes du derme humain ou de myoblastes C2C12. La deuxième technique a pour objet la production de fils présentant des gradients collagène-fibrine, avec ensemencement par des ténoblastes du côté collagène (tendon) et par des myoblastes du côté fibrine (muscle). Nous avons développé un protocole permettant l’extrusion de collagène, fibrine et fibrinogène dans les mêmes conditions, afin de produire des fils purs ou mélangés. L’étude physico-chimique des mécanismes d’assemblage moléculaire a été entreprise. Nous avons construit des dispositifs pour apporter la preuve de concept sur la production de gradients et sur l’impression 3D de nos matériaux. Les fils présentent une forte bioactivité après mise en culture par des myoblastes et ténoblastes primaires murins. En particulier, la fusion des myoblastes, semblable aux cellules satellites sur fibre musculaire isolée, est inhibée dû à la courbure du substrat
Tendon repair is a clinical challenge due to its limited regeneration and its high mechanical solicitation. On the contrary to tendons, myo-tendinous junction rehabilitation has fueled scarce research. Reconstruction is challenging as the purpose is to join stiff tendons to soft muscles. Gradient production, by two different techniques, was chosen to provide resilient junctions and investigate cell-matrix-interaction. The first one enabled to obtain fibrillar macroporous collagen I scaffolds by topotactic fibrillogenesis after freezecasting. The anisotropic micro-ridged scaffolds exhibited unprecedented mechanical properties in wet state, compared to literature, and a hierarchical structure that promoted spontaneous colonization and alignment of Normal Human Dermal Fibroblasts and C2C12 myoblasts. The second technique aimed at the production of threads presenting collagen-to-fibrin gradients, to be seeded with tenoblasts on the collagen side (mimicking tendon) and with myoblasts on fibrin (mimicking muscle). We developed a protocol to extrude fibrin and fibrinogen in the same conditions as collagen and produced pure and mixed threads. Physico-chemical investigation was carried out to understand better the underlying mechanisms of molecular assembly. Threads exhibited different structural and mechanical properties. Using lab-made devices, we established proofs of concept in gradient production and 3D printing. Threads demonstrated high bioactivity when seeded with primary mice tenoblasts and myoblasts. Interestingly, fusion of differentiated myoblasts, similarly to satellite cells on isolated muscle fibers, was inhibited, due to substrate curvature