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Zeitschriftenartikel zum Thema "Monosymptomatic psychotic disorder"

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Debnath, Monojit, Sujit K. Das, Nirmal K. Bera, Chitta R. Nayak und Tapas K. Chaudhuri. „A Study of HLA-Linked Genes in a Monosymptomatic Psychotic Disorder in an Indian Bengali Population“. Canadian Journal of Psychiatry 50, Nr. 5 (April 2005): 269–74. http://dx.doi.org/10.1177/070674370505000507.

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Objective: The etiology of delusional disorder is imperfectly understood. Involvement of biological factors has long been suspected. We examined the incidence of class I human leukocyte antigens (HLAs) in patients with delusional disorder to understand the role of HLA genes and explore a possible immunogenetic etiology for delusional disorder. Methods: We used a nested case–control study design. Psychiatric reference data were available for 27 500 patients registered between 1998 and 2003. Initially, we enrolled 150 patients with delusional disorder from the India-born Bengali population, using DSM-IV diagnostic criteria. After longitudinal follow-up, 80 patients were found to have only delusional disorder, while the remaining 70 patients represented different illnesses with paranoid symptoms and were excluded. We performed serological typing on all 150 patients and applied the polymerase chain reaction–based high-resolution molecular typing method to the 80 patients with delusional disorder. Eighty healthy donors of the same ethnic background, matched for age, sex, and other socioeconomic variables, formed the control group. Results: Some of the HLA alleles were associated with delusional disorder, and the gene HLA-A*03 was found to be significantly more frequent. This gene may influence patients' susceptibility to delusional disorder. Conclusion: The study reveals important associations between HLA genes and delusional disorder. This preliminary observation may help our understanding of this disorder's genetic basis.
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Melle, I. „Hallucinations without delusions in patients with first-episode psychosis: Clinical correlates and implications for pathophysiological models“. European Psychiatry 33, S1 (März 2016): S32. http://dx.doi.org/10.1016/j.eurpsy.2016.01.859.

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IntroductionThe symptomatic distribution in schizophrenia spectrum disorder is heterogeneous. Patients may experience hallucinations, delusions and combinations thereof, in addition to disorganized and negative symptoms. We have previously found that patients with monosymptomatic hallucinations exhibited a different clinical profile than patients with monosymptomatic delusions or combinations of the two; with an earlier age at onset and more suicidal symptoms.AimsTo replicate findings in a new group of patients with schizophrenia spectrum disorders.MethodsA total of 421 consecutive patients with schizophrenia spectrum disorders were included into the study. They were comprehensively assessed by specifically trained psychiatrists or clinical psychologists; using the SCID for DSM-IV for diagnostic purposes, the PANSS to assess current clinical symptoms and CDSS to assess current depression. Lifetime presence of different symptom types was ascertained during the diagnostic interview.ResultsA total of 346 (82%) had experienced both hallucinations and delusion, 63 (15%) had experienced delusions without hallucinations, 10 (2.5%) had experienced hallucinations without delusions and 2 patients (0.5%) had neither but experienced negative and severely disorganized symptoms. Contrary to hypothesis, we did not find any statistically significant differences in age at onset and in clinical symptoms (including suicidality) between these groups. We also did not find any differences in the type of hallucinatory experiences between hallucinating groups.ConclusionsIn a new sample of patients, we did not replicate previous findings of a different clinical profile in patients with monosymptomatic hallucinations. This type of psychotic disorder is relatively rare, which might pose a problem concerning statistical strength.Disclosure of interestThe author has not supplied his declaration of competing interest.
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Vilella Martín, C., P. García Vázquez, P. Fernández Perea, Y. Barrera García, A. Serrano García, J. De Santiago Sastre, R. Gómez Martínez und C. Franch Pato. „Conversion disorder in an 18-year-old boy: a case report“. European Psychiatry 65, S1 (Juni 2022): S398. http://dx.doi.org/10.1192/j.eurpsy.2022.1008.

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Introduction Conversion is the transformation of a conflict (unconscious) into a somatic symptom or a “non-verbal way of expressing psychological discomfort”, through somatizations. The disorder suggests a neurological or medical disease, associated psychological factors appear and is not produced intentionally. Objectives To describe a case of conversion disorder. Methods Retrospective review of clinical records and complementary test, including psychiatry, electrophysiology and neurology. Results An 18-year-old boy came to the emergency room for paralysis. He has anesthesia of lower limbs. He shows indifference towards this symthoms.He denies any stressful situation. On examination, no psychotic or affective symptoms were observed. Belle indifference. Blood tests and a cranial CT scan were performed without alterations, so the patient was admitted for study. The electromyogram, lumbar puncture and cranial magnetic resonance show negative results. Suggestion is carried out, proving effective and recovering gait and sensitivity. These episodes are repeated up to 4 times until finally, during an interview with the family, episodes of bullying come to light. We work in therapy with a diagnosis of conversion disorder. Conclusions The most frequent symptoms in conversion disorder are mutism, paralysis, anesthesia, blindness and seizures. It is usually monosymptomatic for each patient. Diferencial diagnosis with neurological pathology should be made. Disclosure No significant relationships.
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Azevedo, P., F. Monteiro, A. P. Correia, A. Norton und A. M. Moreira. „Isolated Psychiatric Presentation of Anti N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report“. European Psychiatry 33, S1 (März 2016): S524. http://dx.doi.org/10.1016/j.eurpsy.2016.01.1939.

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IntroductionAnti N-Methyl-D-Aspartate receptor (NMDAR) encephalitis is an autoimmune disorder with a presentation that includes acute behavioral changes, psychosis, cognitive impairment and autonomic instability. In some cases, there are isolated psychiatric symptoms without neurological involvement.AimsTo raise awareness of the disorder among psychiatrists, considering it a differential diagnosis in a first psychotic episode since a prompt diagnosis and treatment can dramatically affect the outcome.ObjectivesTo summarize the latest literature about this field and to present a case report.MethodsA brief review of the latest literature was performed on PubMed using the keywords “anti N-methyl-D-aspartate receptor encephalitis”, “anti-NMDA encephalitis”, “psychiatric symptoms”.ResultsA 20-year-old male was admitted to our inpatient unit with bizarre delusions of grandious and religious content, somatic hallucinations, sleep cycle inversion and strange behaviour. These symptoms had been present for 1 week and remitted after 10 days of treatment with risperidone. On follow-up, he developed anhedonia, apathy and blunt affect. Brain MRI showed multiple hyperintense changes in T2 and T2-FLAIR, highly suggestive of demyelinating lesions. The cerebrospinal fluid showed mild lymphocytic pleocytosis, mildly increased proteins, oligoclonal bands and anti-NMDAR antibodies of intrathecal production. He was treated with corticoids and the antipsychotic was discontinued. No neurologic symptoms were ever present.ConclusionThis is an atypical case of anti-NMDAR encephalitis because of its isolated psychiatric presentation. Most patients develop neurological symptoms 2 to 3 weeks after onset of psychiatric symptoms. Monosymptomatic syndromes arise in less than 5% of patients.Disclosure of interestThe authors have not supplied their declaration of competing interest.
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Munro, Alistair. „Monosymptomatic Hypochondriacal Psychosis“. British Journal of Psychiatry 153, S2 (1988): 37–40. http://dx.doi.org/10.1192/s0007125000298978.

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DSM-IIIR (American Psychiatric Association, 1987) has revised the Kraepelinian concept of paranoia, but has given it the name of delusional (paranoid) disorder. The description is of an encapsulated, monodelusional disorder with several subtypes as follows: Erotomanic, Grandiose, Jealous, Persecutory, Somatic, Unspecified.
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Ross, Colin A., A. R. Siddiqui und Manuel Matas. „DSM-III: Problems in Diagnosis of Paranoia and Obsessive-Compulsive Disorder“. Canadian Journal of Psychiatry 32, Nr. 2 (März 1987): 146–48. http://dx.doi.org/10.1177/070674378703200212.

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The diagnoses of paranoia and obsessive-compulsive disorder are not adequately dealt with either conceptually or phenomenologically in DSM-III. A case of monosymptomatic hypochondriacal psychosis illustrating this point is presented. The question of whether this disorder should be diagnosed as paranoia, obsessive-compulsive disorder or an atypical affective disorder is discussed.
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Humphreys, Martin, und Frances Burnett. „4. Monosymptomatic Hypochondriacal Psychosis and Prolonged Solitary Confinement“. Medicine, Science and the Law 34, Nr. 4 (Oktober 1994): 343–46. http://dx.doi.org/10.1177/002580249403400415.

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A man previously imprisoned for 11 years developed unremitting and treatment-resistant monosymptomatic hypochondriacal psychosis following a period in excess of 12 months in solitary confinement. We are unaware of any other reported incidences of this disorder arising in such circumstances.
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Gassiep, Ian, und Paul Matthew Griffin. „Delusions of Disseminated Fungosis“. Case Reports in Infectious Diseases 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/458028.

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Introduction. Delusional infestation is a rare monosymptomatic hypochondriacal psychosis according to The Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5; American Psychiatric Association, 2013). It can be a primary disorder or associated with an underlying psychological or physical disorder. It commonly presents as delusional parasitosis, and less than 1% may be fungi related. We present this case as it is a rare presentation of a rare condition.Case Presentation. Our patient is a 60-year-old Caucasian man who presented with a 7-year history of delusional infestation manifested as a disseminated fungal infection. He had previously been reviewed by multiple physicians for the same with no systemic illness diagnosed. After multiple reviews and thorough investigation we diagnosed him with a likely delusional disorder. As is common with this patient cohort he refused psychiatric review or antipsychotic medication.Conclusion. A delusion of a disseminated fungal infestation is a rare condition. It is exceedingly difficult to treat as these patients often refuse to believe the investigation results and diagnosis. Furthermore, they either refuse or are noncompliant with treatment. Multidisciplinary outpatient evaluation may be the best way to allay patient fears and improve treatment compliance.
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Jaiswal, Saurabh, und Rohit K. Srivastava. „Ekbom's Syndrome: Worms of the Mind“. International Journal of Advanced and Integrated Medical Sciences 1, Nr. 3 (2016): 123–25. http://dx.doi.org/10.5005/jp-journals-10050-10042.

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ABSTRACT Delusional parasitosis (DP), also known as Ekbom syndrome, is a rare, monosymptomatic psychosis where the person has an unshakable belief (i.e., delusion) of being infested with parasites. A detailed activity of the offending parasite like crawling, biting, burrowing is often given by the patients. It is commonly observed among patients over the age of 50. International Classification of Diseases (ICD) 10th revision defines this disorder as “delusional disorder.” We are presenting a case report of a patient suffering from DP, who was successfully treated on atypical antipsychotic olanzapine, together with psychoeducation and counseling. How to cite this article Jaiswal A, Jaiswal S, Srivastava RK. Ekbom's Syndrome: Worms of the Mind. Int J Adv Integ Med Sci 2016;1(3):123-125.
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Sharquie, Khalifa Ebeid, und Maha Sulaiman Younis. „Delusional parasitosis as a tactile hallucination handled by dermatologists“. Our Dermatology Online 13, Nr. 3 (01.07.2022): 254–58. http://dx.doi.org/10.7241/ourd.20223.3.

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Background: Delusional parasitosis (DP) is a false, unshakable belief that pathogens have infested one’s own skin or body. Objective: The objective was to record all patients with DP, a rare presentation of monosymptomatic delusion, in Iraq. Patients and Methods: This was a descriptive study of 21 cases diagnosed with DP in Medical City Teaching Hospital in Baghdad, Iraq, between 2013 and 2021. A detailed history and clinical examination were conducted to exclude actual organic disease. Results: All patients were females with a mean age of 65 years. They believed strongly to have pathogens in their skin or scalp, carrying containers with samples of skin debris, fibers, dead insects, hair waste, and small stones as proofs of their infestation. Careful psychiatric assessment ruled out schizophrenia, substance use disorders, and dementia, and proved the psychiatric diagnosis of monosymptomatic delusion. The patients described their symptoms as something crawling, stinging, and biting sensations. On examination, we often saw shaved scalp hair with injured skin in the form of excoriations, ulcerations, scarring, and pyogenic infections in a localized area. Conclusion: DP is a single symptom-sign complex manifestation in a person with a well-preserved personality apart from a single tactile hallucination of some sort of pathogens infesting their skin. It is commonly a disease of the scalp of elderly females that run a chronic course and rarely remits in a short time. Proper liaison between dermatologists and psychiatrists assisted by laboratory facilities is required for diagnosis and follow-up. Empathetic rapport, psychiatric referral, and early treatment by atypical anti-psychotics significantly improve such conditions.
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Dissertationen zum Thema "Monosymptomatic psychotic disorder"

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Debnath, Monojit. „Analysis of etiology of the delutional disorder, a model monosymptomatic psychotic disorder on the basis of immunogenetic and cytological investigations“. Thesis, University of North Bengal, 2005. http://hdl.handle.net/123456789/1047.

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Bandopadhyay, Sikta. „Molecular investigations of the dopaminergic system in the etiopathology of monosymptomatic psychotic disorder“. Thesis, University of North Bengal, 2009. http://hdl.handle.net/123456789/1406.

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Buchteile zum Thema "Monosymptomatic psychotic disorder"

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Marneros, Andreas. „Delusional disorders“. In New Oxford Textbook of Psychiatry, herausgegeben von John R. Geddes, Nancy C. Andreasen und Guy M. Goodwin, 619–27. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198713005.003.0062.

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Delusional disorders are psychotic disorders, characterized by well-systematized and long-lasting delusions, whereas other mental and personality domains usually remain intact. Their main characteristics are: (1) chronicity—they may last several months, years, or decades, and in some patients even lifelong; (2) stability—they usually are stable, that is, they only rarely shift into another psychotic disorder; (3) monosymptomatic—delusions are the only symptom; in some rare cases, they could be accompanied by other symptoms, like hallucinations, but if they occur, they are not prominent and usually derivable from the delusions; (4) monothematic—the delusions have a single theme and only rarely a combination; (5) they are difficult to be treated; and (6) they are autochthonous, that is, independent, and autonomous, having their own clinical features and rules. Their main phenomenological types are: erotomanic, jealous, persecutory and related types, somatic, mixed, and unspecified, whereas the existence of an independent grandiose type is uncertain.
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