Auswahl der wissenschaftlichen Literatur zum Thema „Model informed approach“

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Zeitschriftenartikel zum Thema "Model informed approach"

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Vorobiev, Oleg, Eric Herbold, Souheil Ezzedine und Tarabay Antoun. „A continuum model for concrete informed by mesoscale studies“. International Journal of Damage Mechanics 27, Nr. 10 (18.09.2017): 1451–81. http://dx.doi.org/10.1177/1056789517730884.

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The paper describes a novel computational approach to refine continuum models for penetration calculations which involves two stages. At the first stage, a trial continuum model is used to model penetration into a concrete target. Model parameters are chosen to match experimental data on penetration depth. Deformation histories are recorded at few locations in the target around the penetrator. In the second stage, these histories are applied to the boundaries of a representative volume comparable to the element size in large scale penetration simulation. Discrete-continuum approach is used to model the deformation and failure of the material within the representative volume. The same deformation histories are applied to a single element which uses the model to be improved. Continuum model may include multiple parameters or functions which cannot be easily found using experimental data. We propose using mesoscale response to constrain such parameters and functions. Such tuning of the continuum model using typical deformation histories experienced by the target material during the penetration allows us to minimize the parameter space and build better models for penetration problems which are based on physics of penetration rather than intuition and ad hoc assumptions.
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Madabushi, Rajanikanth, Yaning Wang und Issam Zineh. „A Holistic and Integrative Approach for Advancing Model‐Informed Drug Development“. CPT: Pharmacometrics & Systems Pharmacology 8, Nr. 1 (Januar 2019): 9–11. http://dx.doi.org/10.1002/psp4.12379.

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Hughes, Hilary, Marcus Foth und Kerry Mallan. „Social living labs for informed learning“. Journal of Information Literacy 13, Nr. 2 (03.12.2019): 112. http://dx.doi.org/10.11645/13.2.2641.

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This paper proposes social living labs for informed learning as an innovative approach to interprofessional and community education. It presents a new conceptual model and practice framework suited to rapidly changing, information-intensive work and social environments. The proposed approach is theoretically informed and evidence based. It integrates concepts from three complementary fields: Informed learning as information literacy pedagogy that enables using information critically and creatively to learn (information science); interprofessional education as a professional learning model with a cross-disciplinary and community reach (health sciences/medicine); and social living labs as informal learning context and problem-solving process (community development). After reviewing relevant literature, the paper introduces the concepts and research that underpin social living labs for informed learning. Then it presents a new conceptual model and a practice framework to guide their design and implementation. To illustrate the practical application of this approach, a hypothetical scenario envisages health practitioners, librarians and community members collaborating in a social living lab to address health and social challenges related to child obesity. The paper concludes by discussing anticipated benefits and limitations of the approach and possible wider application. As a contribution to theory, the paper uncovers a previously unrecognised synergy between the principles of informed learning, social living labs and interprofessional education. Supporting information literacy research and practice, the paper identifies a significant role for informed learning in community and professional education, and a novel strategy for health information literacy development. The paper is of interest to educators, researchers, and practitioners across information literacy, community development, healthcare, and other professional fields.
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Koury, Samantha P., und Susan A. Green. „Developing Trauma-Informed Care Champions: A Six-Month Learning Collaborative Training Model“. Advances in Social Work 18, Nr. 1 (24.09.2017): 145–66. http://dx.doi.org/10.18060/21303.

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This paper describes a six-month learning collaborative for service providers seeking to implement trauma-informed care (TIC) into their agencies. Although the professional literature on trauma-informed care has grown substantially over the past 10 years, little research has focused on how to effectively train agencies in creating a trauma-informed culture shift. Participants were trained as “TIC champions” to help facilitate the creation of trauma-informed approaches in their agencies. Through a parallel process, they learned the skills for planning and implementing a trauma-informed approach in their agency. At the completion of the training, trainers observed champions becoming more confident in their ability to assist their agencies in creating a trauma-informed culture shift. Though quantitative studies evaluating the learning collaborative are needed, initial findings suggest the collaborative approach is an effective means of guiding champions through the process of becoming trauma-informed.
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Wind, Stefanie A., und A. Adrienne Walker. „A Model‐Data‐Fit‐Informed Approach to Score Resolution in Performance Assessments“. Educational Measurement: Issues and Practice 40, Nr. 3 (19.04.2021): 52–63. http://dx.doi.org/10.1111/emip.12427.

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Montgomery, Jacob M., Santiago Olivella, Joshua D. Potter und Brian F. Crisp. „An Informed Forensics Approach to Detecting Vote Irregularities“. Political Analysis 23, Nr. 4 (2015): 488–505. http://dx.doi.org/10.1093/pan/mpv023.

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Electoral forensics involves examining election results for anomalies to efficiently identify patterns indicative of electoral irregularities. However, there is disagreement about which, if any, forensics tool is most effective at identifying fraud, and there is no method for integrating multiple tools. Moreover, forensic efforts have failed to systematically take advantage of country-specific details that might aid in diagnosing fraud. We deploy a Bayesian additive regression trees (BART) model–a machine-learning technique–on a large cross-national data set to explore the dense network of potential relationships between various forensic indicators of anomalies and electoral fraud risk factors, on the one hand, and the likelihood of fraud, on the other. This approach allows us to arbitrate between the relative importance of different forensic and contextual features for identifying electoral fraud and results in a diagnostic tool that can be relatively easily implemented in cross-national research.
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Miller, Faye Q. „Experiencing information use for early career academics’ learning: a knowledge ecosystem model“. Journal of Documentation 71, Nr. 6 (12.10.2015): 1228–49. http://dx.doi.org/10.1108/jd-04-2014-0058.

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Purpose – The purpose of this paper is to explore the informed learning experiences of early career academics (ECAs) while building their networks for professional and personal development. The notion that information and learning are inextricably linked via the concept of “informed learning” is used as a conceptual framework to gain a clearer picture of what informs ECAs while they learn and how they experience using that which informs their learning within this complex practice: to build, maintain and utilise their developmental networks. Design/methodology/approach – This research employs a qualitative framework using a constructivist grounded theory approach (Charmaz, 2006). Through semi-structured interviews with a sample of 14 ECAs from across two Australian universities, data were generated to investigate the research questions. The study used the methods of constant comparison to create codes and categories towards theme development. Further examination considered the relationship between thematic categories to construct an original theoretical model. Findings – The model presented is a “knowledge ecosystem”, which represents the core informed learning experience. The model consists of informal learning interactions such as relating to information to create knowledge and engaging in mutually supportive relationships with a variety of knowledge resources found in people who assist in early career development. Originality/value – Findings from this study present an alternative interpretation of informed learning that is focused on processes manifesting as human interactions with informing entities revolving around the contexts of reciprocal human relationships.
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Khoshkholgh, Sarouyeh, Andrea Zunino und Klaus Mosegaard. „Informed proposal Monte Carlo“. Geophysical Journal International 226, Nr. 2 (29.04.2021): 1239–48. http://dx.doi.org/10.1093/gji/ggab173.

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SUMMARY Any search or sampling algorithm for solution of inverse problems needs guidance to be efficient. Many algorithms collect and apply information about the problem on the fly, and much improvement has been made in this way. However, as a consequence of the No-Free-Lunch Theorem, the only way we can ensure a significantly better performance of search and sampling algorithms is to build in as much external information about the problem as possible. In the special case of Markov Chain Monte Carlo (MCMC) sampling we review how this is done through the choice of proposal distribution, and we show how this way of adding more information about the problem can be made particularly efficient when based on an approximate physics model of the problem. A highly non-linear inverse scattering problem with a high-dimensional model space serves as an illustration of the gain of efficiency through this approach.
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Jongejan, Ruben, Roshanka Ranasinghe und Han Vrijling. „A RISK-INFORMED APPROACH TO COASTAL ZONE MANAGEMENT“. Coastal Engineering Proceedings 1, Nr. 32 (30.01.2011): 8. http://dx.doi.org/10.9753/icce.v32.management.8.

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Economic and population growth have led to an unprecedented increase in the value at risk in coastal zones over the last century. To avoid excessive future losses, particularly in the light of projected climate change impacts, coastal zone managers have various instruments at their disposal. These primarily concern land-use planning (establishing buffer zones) and engineering solutions (beach nourishment and coastal protection). In this paper, we focus on risk mitigation through the implementation of buffer zones (setback lines). Foregoing land-use opportunities in coastal regions and protecting coasts is costly, but so is damage caused by inundation and storm erosion. Defining appropriate setback lines for land-use planning purposes is a balancing act. It is however unclear what level of protection is facilitated by current approaches for defining setback lines, and whether this is, at least from an economic perspective, sufficient. In this paper, we present an economic model to determine which setback lines would be optimal from an economic perspective. The results provide a useful reference point in the political debate about the acceptability of risk in coastal zones. The main conclusions are (i) that it is useful to define setback lines on the basis of their exceedance probabilities, (ii) that the exceedance probability of an economically efficient setback line will typically be in the order of magnitude of 1/100 per year, (iii) that it is important to distinguish between situations in which morphological conditions are stationary and non-stationary, and (iv) that long-term uncertainties (e.g. due to climate change) influence the exceedance probability of efficient setback lines but only to a limited extent.
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Li, Jerry, Mina Nikanjam, Coleen K. Cunningham, Elizabeth J. McFarland, Emily E. Coates, Katherine V. Houser, Bob C. Lin et al. „Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach“. Clinical Pharmacology & Therapeutics 109, Nr. 1 (03.10.2020): 184–92. http://dx.doi.org/10.1002/cpt.2026.

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Dissertationen zum Thema "Model informed approach"

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Leding, Albin. „Recommendation for first pharmacokinetic in vivo experiment design with a pharmacometric informed approach“. Thesis, Uppsala universitet, Institutionen för farmaci, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447311.

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Tuberculosis, the leading cause of death by a single infection disease caused by bacteria, requires long treatments and the bacteria are prone to develop drug resistance. Therefore, new efficient treatment regiments needs developing, which requires new tools for drug development. A major reason for discontinuance of a drug under development is undesired pharmacokinetic properties. Therefore, it is important to have early information of this, preferably the first time the drug is tested in animals. The first in vivo pharmacokinetic experiment is often done in mice and the only information present at this stage are often in vitro values and physicochemical properties. Physiological-based pharmacokinetic modelling can be used to extrapolate from in vitro to in vivo values. From this, the first in vivo pharmacokinetic experiment can be designed, often with the goal of reducing the amount of mice. This goal is one of the three R.s and it is called Reduction. To explore the Reduction of an experiment population pharmacokinetic modelling can be utilized via exploration of the imprecision, bias and probability of an informative experiment to evaluate if a design meets the goal of Reduction. In this report a recommendation of the first in vivo pharmacokinetic experiment is presented. This is based on in vitro values and physicochemical properties that are common in anti-tuberculosis drugs. If the probability of an informative experiment is critical, a terminal sampling of 40 mice is recommended. If imprecision and bias are necessary, zipper sampling of 10 mice is recommended.
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McKay, Ian Ross. „Assessing orientations to cultural difference of the faculty of a university foundation programme in the Gulf Cooperation Council : a mixed-methods approach informed by the Intercultural Development Continuum and using the Intercultural Development Inventory“. Thesis, University of Exeter, 2013. http://hdl.handle.net/10871/13781.

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This study examined the orientations to cultural difference of sojourner educators in the Foundation Program at Qatar University to determine if orientations were correlated with select demographic and experiential variables, including gender, age, time overseas, education level, formative region, ethnic minority status, job position, length of time in Qatar, intercultural marriage, default language, formal teacher training, and overseas development organization experience. This study used a sequential mixed-method design. Perceived and Developmental Orientations were measured using the Intercultural Development Inventory© (V.3), which produced a measure of each respondent’s orientation to cultural difference. Focus group interviews were conducted to engage participants in explaining and interpreting the findings. Five focus groups of three to six participants each were conducted. Most of the teachers were found to operate from within the transitional orientation of Minimization, although individual scores ranged from Denial to Adaptation. On average, the educators were found to overestimate their orientations by 31 points. A positive correlation between orientation and formative region was found, with participants from North America showing the highest orientation. Statistically significant differences emerged for orientations when comparing Middle East and North African (MENA) and North American formative regions. Formative region was found to account for 4.8% of the variance in orientation and is a significant fit of the data. Focus groups participants speculated that (a) core differences regarding multiculturalism in MENA and North American cultures help explain the results, (b) aspects of the workplace culture and both the broader MENA and local Qatari culture encourage a sense of exclusion, and (c) external events further complicate cross-cultural relations. The study findings add to the literature by providing baseline orientation data on sojourner educators in post-secondary education in the GCC region, and by confirming some of the findings of similar studies. The study provides practitioners with suggestions for staffing and professional development. Future research should focus on the measurement of orientations in broader samples of educators, changes in orientation over time in Qatar and other cultural contexts, differences in orientation among short-term vs. long-term expatriates, the impact of employment systems and societal structures on orientations in sojourner educators, the impact of educator orientation to cultural difference on student achievement, and the design of effective cross-cultural professional development for educators.
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Leding, Albin. „Optimized design recommendation for first pharmacokinetic in vivo experiments for new tuberculosis drugs using pharmacometrics modelling and simulation“. Thesis, Uppsala universitet, Institutionen för farmaci, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-447311.

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Tuberculosis, the leading cause of death by a single infection disease caused by bacteria, requires long treatments and the bacteria are prone to develop drug resistance. Therefore, new efficient treatment regiments needs developing, which requires new tools for drug development. A major reason for discontinuance of a drug under development is undesired pharmacokinetic properties. Therefore, it is important to have early information of this, preferably the first time the drug is tested in animals. The first in vivo pharmacokinetic experiment is often done in mice and the only information present at this stage are often in vitro values and physicochemical properties. Physiological-based pharmacokinetic modelling can be used to extrapolate from in vitro to in vivo values. From this, the first in vivo pharmacokinetic experiment can be designed, often with the goal of reducing the amount of mice. This goal is one of the three R.s and it is called Reduction. To explore the Reduction of an experiment population pharmacokinetic modelling can be utilized via exploration of the imprecision, bias and probability of an informative experiment to evaluate if a design meets the goal of Reduction. In this report a recommendation of the first in vivo pharmacokinetic experiment is presented. This is based on in vitro values and physicochemical properties that are common in anti-tuberculosis drugs. If the probability of an informative experiment is critical, a terminal sampling of 40 mice is recommended. If imprecision and bias are necessary, zipper sampling of 10 mice is recommended.
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Menon, Nikhila. „Mobility and pathways to autonomy of women : a study of informal workers in fisheries sector in Kerala, India“. Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/mobility-and-pathways-to-autonomy-of-women-a-study-of-informal-workers-in-fisheries-sector-in-kerala-india(fef45318-9e2d-4936-a9cd-33c16e81d60d).html.

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Mobility and Pathways to Autonomy of Women: A study of informal workers in fisheries sector in Kerala, India Mobility defined as the freedom and ability to move has intrinsic and instrumental values in promoting human development. Paid work which involves mobility associated with work can be a ‘capability-enhancing’ experience when such mobility improves opportunities and enhances freedoms. However, the existing studies have neither examined nor measured mobility with its multiple domains for women. My thesis fills this gap in research by exploring the multiple domains of gendered mobility by measuring mobility as a single construct and analysing whether mobility is a ‘capability’ for women workers which improves autonomy and agency. It is inter-disciplinary as it is situated at the confluence of development studies, human geography and sociological disciplines. The following features of the thesis make it unique in the development studies discipline. First, the contextual setting is unique as it is based in Kerala, which is a socially progressive state in India. The thesis unearths the underlying structural constraints in the Kerala model of social development for transformation of women workers under patriarchy. It is a comparative study which examines the household autonomy and agency of two types of informal women workers in the post-harvest fisheries, namely ‘peeling workers’ linked to production chains and ‘fish vendors’ who are self-employed. Second, the capability approach provides the theoretical framework for the analysis of mobility of women as capability and it introduces a new concept of ‘transformational mobility’. By examining mobility using the Rasch Rating Scale Model (RSM) for the first time in development studies, the thesis operationalises capability measurement by introducing the measurement scale of mobility of women workers which empirically delineates the multiple domains of mobility based on the constraints faced by women. Third, the mixed methods research design using survey data and qualitative interviews of women workers provide better insight and contextual understanding of women’s work. An innovative method, namely, the Crisp set Qualitative Comparative Analysis (CsQCA), explores the causal mechanisms that bring about ‘transformational mobility’ in women workers. The thesis empirically proves the significance of social and human capital factors like caste, low education of spouse and marital status along with the underlying patriarchal structures that determine pathways to transformational mobility and decision making of women. Lastly, the qualitative analysis using classic grounded theory contributes to the emergence of substantive theories for women workers which reflect contrasting agentic behaviour of peeling workers and fish vendors in the context of Kerala. The lack of collective agency among peeling workers questions the claims of Kerala model of development in improving the agency of women. The findings confirm that work mobility associated with informal low paid work is not necessarily a capability for women in fisheries.
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Troncoso, Ruiz Patricio Eduardo. „Beyond the traditional school value-added approach : analysing complex multilevel models to inform external and internal school accountability in Chile“. Thesis, University of Manchester, 2015. https://www.research.manchester.ac.uk/portal/en/theses/beyond-the-traditional-school-valueadded-approach-analysing-complex-multilevel-models-to-inform-external-and-internal-school-accountability-in-chile(010e92ab-7eac-46f9-9f2d-cde3e62c1d18).html.

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In the last few decades, educational research has largely demonstrated the effects of the socio-economic background on academic performance. Traditionally, researchers have used the so-called contextualised value-added (CVA) concept, implemented via multilevel statistical models, to assess variation in learning outcomes arising from schools and pupils. Depending on the stakeholders they intend to inform, two basic types of CVA models can be defined: models for school accountability and models for school choice. School accountability models can be further distinguished according to the ‘recipient’ of the information: internal models provide information for school authorities to improve their own practices, while external models provide information for government officials to assess school performance for policy-making purposes. Despite the evidence in favour of the use of more complex models for school accountability, government practice in Chile has been restricted to the use of raw school averages in standardised tests as indicators of effectiveness, which have been used indiscriminately for the purposes of school accountability and school choice. Using data from the Chilean National Pupil Database (SIMCE 2004-2006), this thesis demonstrates how the traditional CVA (2-level) models fall short in addressing the complex phenomenon of academic performance, especially in the context of a developing and highly unequal country, such as Chile. The novelty of the CVA modelling in this thesis is that it extends and improves the traditional models insofar as they explicitly assess the variation between pupils, classrooms, primary schools, secondary schools and local authorities, as well as the correlation between Mathematics and Spanish Language at all levels. This is done by implementing two univariate 4-level CVA models for progress in Mathematics and Spanish fitted separately via maximum likelihood estimation (MLE) and a bivariate 5-level cross-classified CVA model for progress in both subjects fitted via Markov Chain Monte Carlo (MCMC) estimation. External school accountability measures were derived from the extended univariate and multivariate models and compared to measures derived from a model akin to the traditional approach. A number of key differences were found, leading to the conclusion that further adjustments to the traditional CVA models are not negligible. The univariate 4-level CVA models provide more insight into school accountability than the traditional approach in a straightforward fashion, while the bivariate 5-level model encompasses a more reliable and ultimately comprehensive view on school performance. With regard to internal school accountability, further models were specified with the purpose of analysing pupils' heterogeneity to inform school improvement processes. The concept of "cultural capital" (Bourdieu, 1977) was chosen to shed light on the matter. Since cultural capital is essentially immeasurable, a latent variable was constructed from a group of manifest variables related to access and use of reading materials. From a substantive point of view, this thesis shows how access to all sorts of reading materials and reading habits can have not only a relevant impact on pupils' progress in Language, but also in Mathematics. Finally, this thesis concludes around three main ideas: firstly, school value-added models for school accountability, either external or internal, need to take into account the complexity of influences affecting pupils' academic progress as thoroughly as possible, in order to make a fair assessment of schools' performance and/or to inform school improvement policies. Secondly, school effectiveness is not a unidimensional process, which implies that school value-added models should ideally (when there are available data) reflect upon the multidimensionality of the phenomenon and take into consideration the relationship between different subjects, as well as non-academic outcomes. Thirdly, CVA models can also be used to inform internal school accountability by analysing the effects of meaningful modifiable factors and potentially serve as drivers of school improvement policies.
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Maples, Kevin. „The expository preaching of New Testament quotations of the Old Testament : a patristically informed redemptive-historical model“. Thesis, 2014. http://hdl.handle.net/10500/18596.

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This thesis employs a historical approach to practical theology in an effort to discover resources from past practices for critical reflection upon a current methodology with the intent of producing a revised practice. The following research question is pursued: How can the practices of patristic preachers enhance the current efforts of redemptive-historical preachers to preach faithfully the New Testament quotations of the Old Testament? Chapter One reviews literature from five major redemptive-historical theologians: Geerhardus Vos, Edmund Clowney, Sidney Greidanus, Bryan Chapell, and Graeme Goldsworthy. Five of the major shared characteristics of these authors are considered in light of their various contributions. Chapters Two, Three, and Four examine various patristic homilies, outlining practical considerations for a contemporary model of preaching. Chapter Two examines two early homilies, 2 Clement and Quis Dives Salvetur, noting the influence of the synagogue. Chapters Three and Four respectively examine the preaching of Origen and Chrysostom. Chapter Five outlines some major characteristics of patristic preaching discovered through a comparison of the findings of chapters Two through Four. Chapter Six provides a model for preaching New Testament quotations of the Old Testament that is consistent with the theological convictions of redemptive-historical homileticians and informed by the insights gained from reflection upon the practices of patristic preachers. This model makes an original contribution to knowledge by advancing the discussion of redemptive-historical preaching both through the application of the redemptive-historical approach to the New Testament quotations of the Old Testament and through the consideration of the relationship between redemptive-historical practices and patristic practices.
Practical Theology
D. Th. (Practical Theology)
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Pratt, Deirdre Denise. „A realist approach to writing: developing a theoretical model of written composition to inform a computer mediated learning application“. Thesis, 2007. http://hdl.handle.net/10321/332.

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Thesis (D.Tech.: Language Practice) - Dept. of Language and Translation, Durban University of Technology, 2007
An in-depth investigation into the nature of composing was carried out to provide the theoretical basis for a computer mediated learning application, an interactive writing tutor computer program which might be customised by users to fit different educational contexts. The investigation was carried out within a critical realist perspective, from which viewpoint composing can be seen to have an external reality in common with other social phenomena. The intended outcome was to arrive at a description of writing which more closely approximated the reality so as to design more effective learning interactions, in particular, the writing tutor program itself
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Bücher zum Thema "Model informed approach"

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Cavaciocchi, Simonetta, Hrsg. Le interazioni fra economia e ambiente biologico nell'Europa preindustriale secc. XIII-XVIII. Economic and biological interactions in pre-industrial Europe from the 13th to the 18th centuries. Florence: Firenze University Press, 2010. http://dx.doi.org/10.36253/978-88-8453-596-2.

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Pests, parasites and pathogenic agents have exerted a notable influence on the process of economic development of pre-industrial Europe, in view of their influence on the health, longevity and reproduction of human beings, plants and animals. On each occasion man has reacted to biological uncertainty with responses that were public or private, formal or informal and differed in both efficacy and cost. Success has always been partial, and dependent on experience, knowledge and the investment of economic resources. These reciprocal influences have never been allocated an appropriate or convincing place in the institutional model or those of Smith, Malthus, Ricardo or Marx, typically exploited to describe and explain the flux and reflux of the economic development of pre-industrial Europe. In these proceedings of Study Week promoted by the Fondazione Datini, the leading experts in the sector have undertaken to analyse, exemplify and discuss the precise nature of the complex interactions between economic and biological processes and agents. Adopying a stimulating, innovative and interdisciplinary approach, they appraise the degree to which such processes acted in reciprocal independence, whether there was a significant co-evolution and what prospects there are for developing explanatory models that better grasp the essentially bilateral nature of such interactions.
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Sappok, Tanja, Sabine Zepperitz und Mark Hudson. Meeting Emotional Needs in Intellectual Disability: The Developmental Approach. Hogrefe Publishing, 2021. http://dx.doi.org/10.1027/00589-000.

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Using a developmental perspective, the authors offer a new, integrated model for supporting people with intellectual disability (ID). This concept builds upon recent advances in attachment-informed approaches, by drawing upon a broader understanding of the social, emotional, and cognitive competencies of people with ID, which is grounded in developmental neuroscience and psychology. The book explores in detail how challenging behaviour and mental health difficulties in people with ID arise when their basic emotional needs are not being met by those in the environment. Using individually tailored interventions, which complement existing models of care, practitioners can help to facilitate maturational processes and reduce behavior that is challenging to others. As a result, the ‘fit’ of a person within his or her individual environment can be improved. Case examples throughout the book illuminate how this approach works by targeting interventions towards the person’s stage of emotional development. This book will be of interest to a wide range of professionals working with people with ID, including: clinical psychologists, psychiatrists, occupational therapists, learning disability nurses, speech and language therapists, and teachers in special education settings, as well as parents and caregivers.
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Campbell, Colin, und Jackie Craissati. Introduction. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198791874.003.0001.

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The UK government’s Offender Personality Disorder (OPD) strategy has provided a unique opportunity to revise the way in which health and criminal justice agencies collaborate in order to develop creative psychologically informed approaches to managing a complex group of individuals. This introduction to ‘Managing Personality Disordered Offenders: A Pathways Approach’ outlines the development and implementation of the strategy from the perspective of a consortium of mental health trusts—the London Pathways Partnership (LPP). It outlines the commissioning constraints in this particular geographical setting and details both the theoretical underpinnings and operational models used to implement the OPD pathway in community and secure settings. The chapter concludes with a review of the first four years of these services and a reappraisal of the strategic model.
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Jappelli, Tullio, und Luigi Pistaferri. Non-Standard Preferences. Oxford University Press, 2017. http://dx.doi.org/10.1093/acprof:oso/9780199383146.003.0014.

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In the real world many facts appear to conflict with the assum ptions of the standard life-cycle model and its main hypotheses. The mental accounting model challenges the assumption that resources are fungible. Substantial evidence produced by psychology, laboratory experiments, and empirical studies points out that people do not make time-consistent decisions, leading to the analysis of time-inconsistent preferences and hyperbolic discounting, a model in which rational agents make time-inconsistent decisions. A third critique is that people are in fact not fully informed about financial opportunities (the equity premium, say, or the virtue of diversification). In this chapter we review the literature on financial sophistication. A final departure from the standard approach explicitly models another important fact of life, namely, that our own choices are affected by the choices of other consumers, owing to social preferences.
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French, Jeff. The case for social marketing in public health. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198717690.003.0001.

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This chapter explores the influence of paternalistic conceptions of public health fostered by more generic state paternalism that stresses the responsibility of the state to influence health and the conditions that create it. The limitations of such an approach are reviewed. The chapter also explores the growing realization that governments and their agencies cannot deliver the significant shifts in population-level behaviour change alone, and the implications of this realization. The second half of the chapter sets out the case for a new citizen-informed model of public health practice informed by social marketing principles. The rationale and practical implications of this new citizen-focused model are explored, including the added value contribution that can be made to public health programmes and policy through the application of social marketing principles. The chapter ends with a review of why social marketing is being increasingly applied as standard practice in many parts of the world.
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Entrepreneurship In The Informal Economy Models Approaches And Prospects For Economic Development. Routledge, 2012.

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Roth, Katalin. Bioethical Issues in Integrative Geriatrics. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190466268.003.0030.

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Many older persons use complementary and alternative medicine (CAM), and an integrative approach is very consistent with the holistic model of geriatric “slow medicine.” Ethical practice requires an understanding of the patient’s values and goals of care. The core ethical principles of beneficence, autonomy, and justice are applied to geriatric concerns such as decision-making capacity, prognosis, and advance care planning. Informed consent requires that patients understand the goals of treatment, conventional options, and the evidence and safety of CAM therapies. Legal issues affecting CAM providers such as licensing, referrals, and malpractice are reviewed.
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Campbell, Colin, und Pamela Attwell. Intervening in secure settings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198791874.003.0005.

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The chapter begins by reviewing the existing evidence base for services for personality disordered offenders within secure settings, outlining approaches used both in the UK and internationally. The chapter goes on to describe the implementation of the Offender Personality Disorder (OPD) strategy in secure services, setting out the commissioning context and the focus on social environments, including Psychologically Informed Planned Environments (PIPEs) and Enabling Environments. It reviews the approach chosen by the London Pathways Partnership in terms of service model (residential, day programme, and outreach) and the intensity of the interventions used. The delivery of the services is then described in detail, including the development phase; referrals and assessment; intervention; and pathway progression. The chapter reviews the progress of the services over the first four years, including what worked and what didn’t, and concludes with an outline of evaluations of the services and proposals for future developments.
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Kern, Margaret L., und Howard S. Friedman. Health Psychology. Herausgegeben von Thomas A. Widiger. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199352487.013.2.

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As research on personality and health has moved to developing multitrait, multioutcome models, the five factor approach has shown excellent utility for understanding health, including physical and mental health, longevity, cognitive function, social competence, and productivity. Drawing on a growing arsenal of advanced statistical techniques, studies are testing complex models to explain how personality influences health. Health behaviors, social situations, physiological changes, and various indirect and moderating factors are important pathways connecting personality and health, and reciprocally influence one another. Future personality research will benefit from interdisciplinary approaches, including integrative data analyses of archival data, big data analyses, neuroscientific approaches, and lifespan epidemiology. Bringing together different types of data, innovative methods, and well-specified theories offers the potential to understand the personality–health model in ways never before imagined. Identifying pathways and key factors in turn will inform effective intervention to help more people live healthier, more productive lives.
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Riskin, Loren, und Alex Macario. Complex Systems and Approaches to Quality Improvement. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199366149.003.0010.

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This chapter, “Complex Systems and Approaches to Quality Improvement,” serves as an introduction to complex systems management and current thinking in improvement science. It explains the context behind quality improvement (QI) initiatives, beginning with a discussion of the ultimate goals of this movement. It then briefly reviews the history of QI development and early leaders in the field. The universal elements of a successful QI or patient safety project are discussed, followed by the exploration of commonly encountered barriers to systems and individual improvement. The chapter also highlights the differences between QI work and traditional research study. Selected tools to examine and prevent risk are explored, including informal approaches, Deming’s model for improvement, Six Sigma, healthcare failure mode and effects analysis (HFMEA), and root cause analysis (RCA).
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Buchteile zum Thema "Model informed approach"

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Zorzetti, Maximilian, Ingrid Signoretti, Eliana Pereira, Larissa Salerno, Cassiano Moralles, Cássio Trindade, Michele Machado, Ricardo Bastos und Sabrina Marczak. „A Practice-Informed Conceptual Model for a Combined Approach of Agile, User-Centered Design, and Lean Startup“. In Product-Focused Software Process Improvement, 142–50. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-64148-1_9.

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Salameh, Abdallah, und Julian M. Bass. „Spotify Tailoring for Architectural Governance“. In Agile Processes in Software Engineering and Extreme Programming – Workshops, 236–44. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58858-8_24.

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Abstract Organisations usually tailor Agile methods to fit their needs best. Spotify has developed its own Agile culture to facilitate software development for hundreds of developers across multiple cities. The Spotify model has become influential among agile proponents and hence formed the basis of methods used in other organisations. We have identified a lack of research into agile architecture using the Spotify model. To explore How can architectural governance increase the autonomy of teams when using the Spotify model?, an intervention embedded case study was conducted in a multinational FinTech organisation, using the Spotify model. New processes were introduced by developing and evaluating an approach to Agile architectural governance. This approach incorporates a structural change and a change management process. We conducted 6 semi-structured open-ended interviews and direct observations of Agile practices. The collected data was analysed using Thematic Analysis and informed by some Grounded Theory techniques. The practitioners in our study report benefits of this evaluated approach. These benefits include transforming architectural based decision into decentralised based decision-making, strengthening the autonomy of squads through aligning architectural based decisions, sharing the architectural knowledge among the squads, and other benefits. We identify the characteristics and benefits of our evaluated approach to Agile architectural governance using the Spotify model. Also, we identify guidelines and challenges for those wishing to adopt this approach.
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Wang, Ting, Phillip K. Wood und Andrew C. Heath. „Can Psychometric Measurement Models Inform Behavior Genetic Models? A Bayesian Model Comparison Approach“. In Springer Proceedings in Mathematics & Statistics, 231–59. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20585-4_10.

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Norling, Emma, Bruce Edmonds und Ruth Meyer. „Informal Approaches to Developing Simulation Models“. In Understanding Complex Systems, 61–79. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-66948-9_5.

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Norling, Emma, Bruce Edmonds und Ruth Meyer. „Informal Approaches to Developing Simulation Models“. In Understanding Complex Systems, 39–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-540-93813-2_4.

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Livingston, Jordan L., Lauren E. Kahn und Elliot T. Berkman. „Motus Moderari: A Neuroscience-Informed Model for Self-Regulation of Emotion and Motivation“. In Handbook of Biobehavioral Approaches to Self-Regulation, 189–207. New York, NY: Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1236-0_13.

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Renton, M., und D. Savage. „Statistical emulators of simulation models to inform surveillance and response to new biological invasions.“ In Biosecurity surveillance: quantitative approaches, 296–312. Wallingford: CABI, 2015. http://dx.doi.org/10.1079/9781780643595.0296.

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Scherer, Daniel, Ademar V. Netto, Yuska P. C. Aguiar und Maria de Fátima Q. Vieira. „Programming a User Model with Data Gathered from a User Profile“. In Cognitively Informed Intelligent Interfaces, 235–57. IGI Global, 2012. http://dx.doi.org/10.4018/978-1-4666-1628-8.ch014.

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In order to prevent human error, it is essential to understand the nature of the user’s behaviour. This chapter proposes a combined approach to increase knowledge of user behaviour by instantiating a programmable user model with data gathered from a user profile. Together, the user profile and user model represent, respectively, the static and dynamic characteristics of user behaviour. Typically, user models have been employed by system designers to explore the user decision-making process and its implications, since user profiles do not account for the dynamic aspects of a user interaction. In this chapter, the user profile and model are employed to study human errors—supporting an investigation of the relationship between user errors and user characteristics. The chapter reviews the literature on user profiles and models and presents the proposed user profile and model. It concludes by discussing the application of the proposed approach in the context of electrical systems’ operation.
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Páscoa, Carlos, Benjamin Fernandes und José Tribolet. „Informed Governance“. In Handbook of Research on Information Architecture and Management in Modern Organizations, 363–81. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-8637-3.ch016.

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How can an organization be successful if it doesn't have clear objectives? If it does not know where to go, how can it plot a route? An organization without well-defined objectives is like a drifting ship, goes along with the winds, wherever it blows to. Defining objectives is of capital importance for good organizational performance and success, vision alignment and goal focusing. Their definition must follow strict requirements that guarantee relevance and accomplishment. Moreover, objectives must be set at all levels of the organization, so that everybody tracks the same route. This research proposes an approach to the way organizations define objectives. Based on principles of Organizational Engineering and the Portuguese Air Force's top-down structure and Mission, a model is proposed that takes into account relevant organizational elements needed to guarantee the objectives' pertinence. It also provides strategies that can be used to align them with the management levels.
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Dombo, Eileen A., und Christine Anlauf Sabatino. „Engaging Teachers, Families, and Kids in Creating Trauma-Informed School Environments“. In Creating Trauma-Informed Schools, 78–89. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190873806.003.0007.

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Chapter 7 explores the essential framework for creating a customized trauma-informed model for schools that engages all stakeholders, including children, parents, communities, teachers, and school administrators, in this paradigm shift. A multitiered approach that includes the four basic assumptions of trauma-informed care is presented, and models of trauma-informed schools are reviewed. Lessons learned from other areas of social work practice, such as child welfare and mental health, are included as well. Case examples of implementation in different school settings demonstrate how to implement the strategies and how the strategies can affect children. Finally, resources for implementation are provided.
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Konferenzberichte zum Thema "Model informed approach"

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Katrakazas, Panagiotis, Ourania Manta und Dimitrios Koutsouris. „A Big-Data Informed Model Approach to Hearing Health Policy Decision Making“. In 2018 14th International Conference on Signal-Image Technology & Internet-Based Systems (SITIS). IEEE, 2018. http://dx.doi.org/10.1109/sitis.2018.00116.

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Yakush, Sergey E., Nazar T. Lubchenko und Pavel Kudinov. „Risk-Informed Approach to Debris Bed Coolability Issue“. In 2012 20th International Conference on Nuclear Engineering and the ASME 2012 Power Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/icone20-power2012-55186.

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Coolability of an ex-vessel debris bed in severe accident conditions is considered from the risk perspective. The concept of “load versus capacity” is employed to quantify the probability of failure (local dryout). Possible choices of “load” and “capacity” in terms of heat fluxes, thermal power or melt mass are discussed. Results of Monte Carlo simulations of distribution functions for the local heat flux and the dryout heat flux at the debris bed top point (defined as the extensions of one-dimensional counterparts) are presented. A surrogate model for the dryout heat flux is developed by the generalization of two-dimensional simulation results. Dryout probabilities are obtained under the conservative assumptions (neglecting the coolability improvement due to side ingress of water into a non-flat debris bed), and from the surrogate model. Outlook is given for the prospective development of the risk-informed approach to debris bed coolability in the context of comprehensive severe accident risk analysis.
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Meyer, Stephen, und Eddie A. Krantz. „Risk-Informed Hazard Barrier Assessment“. In 12th International Conference on Nuclear Engineering. ASMEDC, 2004. http://dx.doi.org/10.1115/icone12-49327.

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There are a number of hazard barriers installed in power plants. The removal of hazard barriers from service can currently require substantial plant resources to evaluate. These evaluations are usually performed to assess the impact of an open barrier on a plant’s licensing basis and fire protection program and are deterministic in nature. The risk-informed approach to hazard barrier assessment helps alleviate the constraints and manpower requirements imposed by the deterministic approaches currently used. A two-step approach has been developed for performing a risk-informed hazard barrier assessment. The objectives of the first step “Data Gathering” are to review the previously performed analyses and to perform the plant walkdowns and data collection needed for the study. In the second step “Model Development and Quantification” using the most recent Probabilistic Safety Assessment (PSA) system models and the results of the “Data Gathering” walkdowns, a set of fault tree/event tree models are prepared for each unique scenario or hazard to be evaluated. The overall set of barrier impairment impacts is binned into a smaller number of generic categories for the PSA analysis. The quantification results will enable utility management to manage the risk of taking barriers out of service and to make a determination of which barriers could be candidates for a risk-informed impairment out-of-service limit if desired.
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Rai, Ashwin, Nithya Subramanian und Aditi Chattopadhyay. „Atomistically Informed Method of Cells Based Multiscale Approach for Analysis of CFRP Composites“. In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65447.

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In this paper a multiscale-modeling framework is presented wherein fundamental damage information at the atomic level is coupled with a sectional micromechanics model for the nonlinear and damage analysis of carbon fiber reinforced polymer (CFRP) composites. Damage information in the polymer matrix originating from the atomic scale, as investigated using molecular dynamics (MD) simulations, is transferred to the continuum length scale using a continuum damage mechanics approach with a physical damage evolution equation. Such a framework is shown to be computationally efficient for the linear and damage analysis of CFRP composites and reasonably accurate when compared to experimental data and verified models in literature. Furthermore, material uncertainty, such as curing degree variation in polymers, can be computationally calculated leading to a computational stochastic analysis of the CFRP composites. Thus, such a framework can be used to investigate the damage mechanics of ply level CFRP components at the nano, micro and macro length scales.
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Zorzetti, Maximilian, Ingrid Signoretti, Eliana Pereira, Larissa Salerno, Cassiano Moralles, Michele Machado, Ricardo Bastos und Sabrina Marczak. „An Empirical-informed Work Process Model for a Combined Approach of Agile, User-Centered Design, and Lean Startup“. In SBQS'20: 19th Brazilian Symposium on Software Quality. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3439961.3439967.

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Alzbutas, Robertas. „Risk-Informed Decisions Optimization in Inspection and Maintenance“. In 10th International Conference on Nuclear Engineering. ASMEDC, 2002. http://dx.doi.org/10.1115/icone10-22415.

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The Risk-Informed Approach (RIA) used to support decisions related to inspection and maintenance program is considered. The use of risk-informed methods can help focus the adequate in-service inspections and control on the more important locations of complex dynamic systems. The focus is set on the highest risk measured as conditional core damage frequency, which is produced by the frequencies of degradation and final failure at different locations combined with the conditional failure consequence probability. The probabilities of different degradation states per year and consequences are estimated quantitatively. The investigation of inspection and maintenance process is presented as the combination of deterministic and probabilistic analysis based on general risk-informed model, which includes the inspection and maintenance program features. Such RIA allows an optimization of inspection program while maintaining probabilistic and fundamental deterministic safety requirements. The failure statistics analysis is used as well as the evaluation of reliability of inspections. The assumptions regarding the effectiveness of the inspection methods are based on a classification of the accessibility of the welds during the inspection and on the different techniques used for inspection. The probability of defect detection is assumed to depend on the parameters either through logarithmic or logit transformation. As example the modeling of the pipe systems inspection process is analyzed. The means to reduce a number of inspection sites and the cumulative radiation exposure to the NPP inspection personnel with a reduction of overall risk is presented together with used and developed software. The developed software can perform and administrate all the risk evaluations and ensure the possibilities to compare different options and perform sensitivity analysis. The approaches to define an acceptable level of risk are discussed. These approaches with appropriate software in partial case is used for the construction and research of the models related to inspections and maintenance planning of Ignalina Nuclear Power Plant (RBMK-1500) piping components. The discussed example is related to risk analysis and inspection program improvements for selected pipe systems. The new risk-informed inspection and maintenance program for selected pipe systems are compared with various alternatives. The usage of risk evaluations to optimize the selection of inspection locations, the inspection interval, and the changes in risk and cost due suggested modifications are demonstrated. The proposed integrated modeling methodic and general model of inspection process can be used as a base for other risk-informed models of inspection process control and risk monitors of complex dynamic systems.
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Tormen, Damiano, Pietro Giannattasio, Alessandro Zanon, Helmut Kühnelt und Michele De Gennaro. „Application of a RANS-Informed Analytical Model for Fast Noise Prediction of Contra Rotating Open Rotors“. In ASME Turbo Expo 2017: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/gt2017-64162.

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The present work focuses on the fast prediction of the interaction noise (IN) components of a Contra Rotating Open Rotor (CROR) engine at take-off. The flow field past the CROR is computed using a steady RANS approach coupled with the concept of mixing plane between the rotors to remove the flow unsteadiness due to the propeller interaction. The effects of such interaction are then recovered applying the analytical model of Jaron et al. (2014), balanced with data extracted from the RANS solution, to extrapolate the information about the wake of the front rotor and the potential flow fields through the mixing plane. This RANS-informed approximation allows recovering the unsteadiness of the flow-blades interaction in terms of unsteady blade response. The tonal noise at the blade passing frequency and the interaction noise are then estimated using the analytical frequency domain model proposed by Hanson (1985). The present method for the fast prediction of CROR noise has been validated by comparison with the results of URANS simulations and noise measurements. CROR geometry UDF F7/A7 with both 8 × 8 and 11 × 9 blade counts has been considered. The flow velocity profiles extrapolated through the mixing plane agree well with the URANS results, except in the vicinity of the blade tip, where the analytical extrapolation method is not able to deal properly with the strongly 3D tip vortex flow. The comparison of the predicted interaction noise with acoustic measurements shows that the present fast RANS-informed approach is capable of estimating the directivity of the CROR noise with reasonable accuracy.
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Muenzer, Clemens, und Kristina Shea. „A Simulation-Based CDS Approach: Automated Generation of Simulation Models Based From Generated Concept Model Graphs“. In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-47353.

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Current approaches in Computational Design Synthesis enable the human designer to explore large solution spaces for engineering design problems. To extend this to support designers in embodiment and detail design, not only the generation of solutions spaces is needed, but also the automated evaluation of engineering performance. Here, simulation methods can be used effectively to predict the behavior of a product. This paper presents a generic approach to automatically generate solution spaces for energy- and signal-based engineering design tasks using first-order logic and Boolean satisfiability. These solution spaces not only include the graph-based product concept topologies but also corresponding bond-graph based simulation models. To do this, guidelines to create partial simulation models for the available building blocks for the synthesis are presented, to assure a valid causality in the final simulation model. Considering the connections in the graph-based product concepts, the simulation models are automatically generated and, simulated. The simulation results are then stored to enable a more informed decision as to which concepts to pursue in detail design. The method is validated using automotive powertrains as a case study. 162 different powertrain concepts are generated and evaluated, showing the advantages of electric powertrains in respect to CO2 emissions and the importance of intelligent control strategies for hybrid ones. This research enables the generation, exploration, and evaluation of solution spaces for energy- and signal-based product concept. Guidelines to define compatible bond-graph based partial simulation models that map to building blocks from an object-oriented graph-based knowledge representation are introduced. Additionally, a generic translation between the graph-based product concepts and simulation models is presented.
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Ford, Michael, und Peter James. „A Monte Carlo Implementation of the James-Ford-Jivkov Microstructurally Informed Local Approach Applied to Predict Fracture Toughness Across Irradiation Conditions“. In ASME 2016 Pressure Vessels and Piping Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/pvp2016-63464.

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The need to predict changes in fracture toughness for materials where the tensile properties change through life, such as with irradiation, whilst accounting for geometric constraint effects, such as crack size, are clearly important. Currently one of the most likely approaches by which to develop such ability are through application of local approach models. These approaches appear to be sufficient in predicting lower shelf toughness under high constraint conditions, but may fail when attempting to predict toughness in the transition region, for low constraint geometries or for different irradiation states, when using the same parameters, making reliable predictions impossible. Cleavage toughness predictions in the transition regime are here made with a stochastic, Monte Carlo implementation of the recently proposed James-Ford-Jivkov model. This implementation is based around the creation of individual initiators following the experimentally observed distribution for specific reactor pressure vessel steel, and determining if these initiators form voids or cause cleavage failure using the model’s improved criterion for particle failure. This implementation has been presented previously in PVP2015-45905, where it was successfully applied across different constraint conditions; in the work presented here it is applied across different irradiation conditions for a second type of steel. The model predicts the fracture toughness in a large part of the transition region, demonstrates an ability to predict the irradiation shift and shows a level of scatter similar to that observed experimentally. All results presented, for a given material, are obtained without changes in the model parameters. This suggests that the model can be used predicatively for assessing toughness changes due to constraint-, irradiation- and temperature-driven plasticity changes.
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Poghosyan, Shahen, Armen Amirjanyan und Albert Malkhasyan. „Approach on Component Selection for Ageing-Trend Analysis Within PSA Models“. In 17th International Conference on Nuclear Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/icone17-75029.

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The major advantage of PSA is the possibility of in-depth qualitative and quantitative analysis of NPP actual configuration with definition of factors introducing a significant contribution to the general risk of reactor core damage. However main lack of the PSA current models is neglect of equipment ageing effects. Neglecting of ageing effects in PSA could lead to incorrectness of risk profile and influent on risk-informed decision making process. To solve this issue incorporation of ageing aspects into PSA models for Armenian NPP Unit 2 was initiated. Implementation of ageing trend analysis for all PSA components is insuperable effort, so the first step of the analysis is component selection activity. This paper is addressing the approach on component selection for ageing-trend analysis within PSA models. Presented approach is based on ageing effect and risk importance data. The procedure was developed and implemented in the framework of ageing aspects incorporation into PSA level 1 model for Armenian NPP Unit 2.
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Berichte der Organisationen zum Thema "Model informed approach"

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Seale, Maria, Natàlia Garcia-Reyero, R. Salter und Alicia Ruvinsky. An epigenetic modeling approach for adaptive prognostics of engineered systems. Engineer Research and Development Center (U.S.), Juli 2021. http://dx.doi.org/10.21079/11681/41282.

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Prognostics and health management (PHM) frameworks are widely used in engineered systems, such as manufacturing equipment, aircraft, and vehicles, to improve reliability, maintainability, and safety. Prognostic information for impending failures and remaining useful life is essential to inform decision-making by enabling cost versus risk estimates of maintenance actions. These estimates are generally provided by physics-based or data-driven models developed on historical information. Although current models provide some predictive capabilities, the ability to represent individualized dynamic factors that affect system health is limited. To address these shortcomings, we examine the biological phenomenon of epigenetics. Epigenetics provides insight into how environmental factors affect genetic expression in an organism, providing system health information that can be useful for predictions of future state. The means by which environmental factors influence epigenetic modifications leading to observable traits can be correlated to circumstances affecting system health. In this paper, we investigate the general parallels between the biological effects of epigenetic changes on cellular DNA to the influences leading to either system degradation and compromise, or improved system health. We also review a variety of epigenetic computational models and concepts, and present a general modeling framework to support adaptive system prognostics.
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Dutra, Lauren M., Matthew C. Farrelly, Brian Bradfield, Jamie Ridenhour und Jamie Guillory. Modeling the Probability of Fraud in Social Media in a National Cannabis Survey. RTI Press, September 2021. http://dx.doi.org/10.3768/rtipress.2021.mr.0046.2109.

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Cannabis legalization has spread rapidly in the United States. Although national surveys provide robust information on the prevalence of cannabis use, cannabis disorders, and related outcomes, information on knowledge, attitudes, and beliefs (KABs) about cannabis is lacking. To inform the relationship between cannabis legalization and cannabis-related KABs, RTI International launched the National Cannabis Climate Survey (NCCS) in 2016. The survey sampled US residents 18 years or older via mail (n = 2,102), mail-to-web (n = 1,046), and two social media data collections (n = 11,957). This report outlines two techniques that we used to problem-solve several challenges with the resulting data: (1) developing a model for detecting fraudulent cases in social media completes after standard fraud detection measures were insufficient and (2) designing a weighting scheme to pool multiple probability and nonprobability samples. We also describe our approach for validating the pooled dataset. The fraud prevention and detection processes, predictive model of fraud, and the methods used to weight the probability and nonprobability samples can be applied to current and future complex data collections and analysis of existing datasets.
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Qhotsokoane, Tebello, Beatriz Kira und Simphiwe Laura Stewart. Fostering inclusive economic growth: the case of the Digital Code of Benin. Digital Pathways at Oxford, April 2021. http://dx.doi.org/10.35489/bsg-dp-wp_2021/02.

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This policy note seeks to elucidate the opportunities for development in Republic of Benin’s digital code, as the country attempts to become a regional example of progress in the digital sphere. The note examines the Digital Code of Benin which sets out a comprehensive set of laws and regulations aimed at providing a secure and conducive environment for digital transformation and innovation. By assessing the key strengths and opportunities for development, this policy note can also inform regional approaches to regulation of the digital economy, especially since Benin is seen as a model for the region.
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Slotiuk, Tetiana. CONCEPT OF SOLUTIONS JOURNALISM MODEL: CONNOTION, FUNCTIONS, FEATURES OF FUNCTIONING. Ivan Franko National University of Lviv, März 2021. http://dx.doi.org/10.30970/vjo.2021.50.11097.

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The article examines the main features, general characteristics and essence of the concept of solutions journalism. The basic principles of functioning of this model of journalism in the western press and in Ukraine are given. The list and features of activity of the organizations, institutes and editorial offices supporting development of journalism of solutions journalism. The purpose of the publication is to describe the Solutions Journalism model: its features, characteristics and features of functioning, to find out the difference in the understanding of the concept of «solutions journalism» and «constructive journalism» in general. The task of the publication was to conceptualize the main trends in the development of solutions journalism in the Western and Ukrainian information space; show the main characteristics, formats of functioning and analyze the features of the concepts of «solutions journalism» and «constructive journalism». Applied research methods: at the stage of research of the history of formation of the concept of Solutions Journalism the historical method is used. The hermeneutic method of research helped in the interpretation of basic concepts, the phenomenological approach was applied in the context of considering the essence of the phenomenon of solutions journalism. At the stage of generalization of the features of the concepts of Solutions Journalism and «constructive journalism» a comparative method was used, which gave an understanding of the common components in their essence. The method of analysis allowed to expand the understanding of the purpose of Solutions Journalism as a type of social journalism and its main tasks. With the help of synthesis it was possible to comprehensively understand the concept of Solutions Journalism and understand its features. In Ukraine, this type of journalism is just emerging, but its introduction into the editorial policy of the media may have a national importance. These are regional and local media that can inform their communities about the positive solution of certain problems in other communities, and thus thanks to this model can save local journalism. In the scientific context, there is a need to outline the main differences in the understanding of the concepts of decision journalism and constructive journalism, to understand the socio-psychological need to create good news.
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Baloch, Imdad, Tom Kaye, Saalim Koomar und Chris McBurnie. Pakistan Topic Brief: Providing Distance Learning to Hard-to-reach Children. EdTech Hub, Juni 2020. http://dx.doi.org/10.53832/edtechhub.0026.

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The COVID-19 pandemic has resulted in mass school closures across the world. It is expected that the closures in low- and -middle-income countries (LMICs) will have long-term negative consequences on education and also on broader development outcomes. Countries face a number of obstacles to effectively delivering alternative forms of education. Obstacles include limited experience in facing such challenges, limited teacher digital and pedagogical capacity, and infrastructure constraints related to power and connectivity. Furthermore, inequalities in learning outcomes are expected to widen within LMICs due to the challenges of implementing alternative modes of education in remote, rural or marginalised communities. It is expected that the most marginalised children will feel the most substantial negative impacts on their learning outcomes. Educational technology (EdTech) has been identified as a possible solution to address the acute impact of school closures through its potential to provide distance education. In this light, the DFID Pakistan team requested the EdTech Hub develop a topic brief exploring the use of EdTech to support distance learning in Pakistan. Specifically, the team requested the brief explore ways to provide distance education to children in remote rural areas and urban slums. The DFID team also requested that the EdTech Hub explore the different needs of those who have previously been to school in comparison to those who have never enrolled, with reference to EdTech solutions. In order to address these questions, this brief begins with an overview of the Pakistan education landscape. The second section of the brief explores how four modes of alternative education — TV, interactive radio instruction, mobile phones and online learning — can be used to provide alternative education to marginalised groups in Pakistan. Multimodal distance-learning approaches offer the best means of providing education to heterogeneous, hard-to-reach groups. Identifying various tools that can be deployed to meet the needs of specific population segments is an important part of developing a robust distance-learning approach. With this in mind, this section highlights examples of tools that could be used in Pakistan to support a multimodal approach that reaches the most hard-to-reach learners. The third and final section synthesises the article’s findings, presenting recommendations to inform Pakistan’s COVID-19 education response.<br> <br> This topic brief is available on Google Docs.
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Lapcha, Haidar, und Yusra Mahdi. Coalition Building for Better Religious Education Reform. Institute of Development Studies (IDS), Januar 2021. http://dx.doi.org/10.19088/creid.2021.002.

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Developing a good pro-pluralism religious education curriculum requires much planning and a deep understanding of the context. In a country like Iraq, where the education system is in decline due to years of conflict, weak governance and management, and a displacement crisis, this becomes a challenging task. This Learning Briefing, prepared during the implementation phase of the Coalition for Religious Equality and Inclusive Development (CREID) project to introduce reform to the religious education curriculum in Iraq, highlights the key areas of best practices and lessons learned from our stakeholder engagement. The aim is to share these learnings with programme managers, donors and partners to help inform future interventions and curricula development on effective approaches and models for improved quality education.
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Haarsager, Ulrike, Claudia Figueroa, Chiaki Yamamoto, Fernando Barbosa, Anna Funaro, Galia Rabchinsky, Melanie Putic et al. Evaluation of IDB Lab: Strategic Relevance. Inter-American Development Bank, Juni 2021. http://dx.doi.org/10.18235/0003405.

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This report presents the findings of the first phase of an evaluation of IDB Lab, which until 2018 was known as the Multilateral Investment Fund (MIF). The mandate for this independent evaluation stems from the second capital replenishment of the MIF (MIF III), which was approved by MIF Donors in April 2017 and became effective in March 2019. The Agreement Establishing the MIF III lays out the expected functions of the Fund and establishes that, any time after the first anniversary of the MIF III, IDB's Office of Evaluation and Oversight (OVE) is to conduct an independent evaluation to: i. Review MIF results in light of the purpose and functions of the MIF III Agreement; ii. Assess MIF operations for relevance, effectiveness, efficiency, innovation, sustainability, and additionality; iii. Determine to what extent progress has been made on implementing the approved recommendations of OVE's 2013 evaluation of the MIF. Donors requested that OVE deliver an evaluation of IDB Lab in 2021 to inform discussions about the Lab's future and funding model. As a result, OVE included this evaluation in its 2020/2021 work program and developed an Approach Paper (Annex V) issued in October 2020. OVE is conducting the evaluation in two overlapping phases. The first phase, conducted from April 2020 to May 2021, evaluated the relevance of IDB Lab's mandate, strategic focus, and corporate setup. Its findings are presented in this report. A second phase of the evaluation, currently ongoing, evaluates IDB Lab operations. This is OVE's third independent corporate evaluation of the MIF requested by Donors.
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McKenna, Patrick, und Mark Evans. Emergency Relief and complex service delivery: Towards better outcomes. Queensland University of Technology, Juni 2021. http://dx.doi.org/10.5204/rep.eprints.211133.

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Emergency Relief (ER) is a Department of Social Services (DSS) funded program, delivered by 197 community organisations (ER Providers) across Australia, to assist people facing a financial crisis with financial/material aid and referrals to other support programs. ER has been playing this important role in Australian communities since 1979. Without ER, more people living in Australia who experience a financial crisis might face further harm such as crippling debt or homelessness. The Emergency Relief National Coordination Group (NCG) was established in April 2020 at the start of the COVID-19 pandemic to advise the Minister for Families and Social Services on the implementation of ER. To inform its advice to the Minister, the NCG partnered with the Institute for Governance at the University of Canberra to conduct research to understand the issues and challenges faced by ER Providers and Service Users in local contexts across Australia. The research involved a desktop review of the existing literature on ER service provision, a large survey which all Commonwealth ER Providers were invited to participate in (and 122 responses were received), interviews with a purposive sample of 18 ER Providers, and the development of a program logic and theory of change for the Commonwealth ER program to assess progress. The surveys and interviews focussed on ER Provider perceptions of the strengths, weaknesses, future challenges, and areas of improvement for current ER provision. The trend of increasing case complexity, the effectiveness of ER service delivery models in achieving outcomes for Service Users, and the significance of volunteering in the sector were investigated. Separately, an evaluation of the performance of the NCG was conducted and a summary of the evaluation is provided as an appendix to this report. Several themes emerged from the review of the existing literature such as service delivery shortcomings in dealing with case complexity, the effectiveness of case management, and repeat requests for service. Interviews with ER workers and Service Users found that an uplift in workforce capability was required to deal with increasing case complexity, leading to recommendations for more training and service standards. Several service evaluations found that ER delivered with case management led to high Service User satisfaction, played an integral role in transforming the lives of people with complex needs, and lowered repeat requests for service. A large longitudinal quantitative study revealed that more time spent with participants substantially decreased the number of repeat requests for service; and, given that repeat requests for service can be an indicator of entrenched poverty, not accessing further services is likely to suggest improvement. The interviews identified the main strengths of ER to be the rapid response and flexible use of funds to stabilise crisis situations and connect people to other supports through strong local networks. Service Users trusted the system because of these strengths, and ER was often an access point to holistic support. There were three main weaknesses identified. First, funding contracts were too short and did not cover the full costs of the program—in particular, case management for complex cases. Second, many Service Users were dependent on ER which was inconsistent with the definition and intent of the program. Third, there was inconsistency in the level of service received by Service Users in different geographic locations. These weaknesses can be improved upon with a joined-up approach featuring co-design and collaborative governance, leading to the successful commissioning of social services. The survey confirmed that volunteers were significant for ER, making up 92% of all workers and 51% of all hours worked in respondent ER programs. Of the 122 respondents, volunteers amounted to 554 full-time equivalents, a contribution valued at $39.4 million. In total there were 8,316 volunteers working in the 122 respondent ER programs. The sector can support and upskill these volunteers (and employees in addition) by developing scalable training solutions such as online training modules, updating ER service standards, and engaging in collaborative learning arrangements where large and small ER Providers share resources. More engagement with peak bodies such as Volunteering Australia might also assist the sector to improve the focus on volunteer engagement. Integrated services achieve better outcomes for complex ER cases—97% of survey respondents either agreed or strongly agreed this was the case. The research identified the dimensions of service integration most relevant to ER Providers to be case management, referrals, the breadth of services offered internally, co-location with interrelated service providers, an established network of support, workforce capability, and Service User engagement. Providers can individually focus on increasing the level of service integration for their ER program to improve their ability to deal with complex cases, which are clearly on the rise. At the system level, a more joined-up approach can also improve service integration across Australia. The key dimensions of this finding are discussed next in more detail. Case management is key for achieving Service User outcomes for complex cases—89% of survey respondents either agreed or strongly agreed this was the case. Interviewees most frequently said they would provide more case management if they could change their service model. Case management allows for more time spent with the Service User, follow up with referral partners, and a higher level of expertise in service delivery to support complex cases. Of course, it is a costly model and not currently funded for all Service Users through ER. Where case management is not available as part of ER, it might be available through a related service that is part of a network of support. Where possible, ER Providers should facilitate access to case management for Service Users who would benefit. At a system level, ER models with a greater component of case management could be implemented as test cases. Referral systems are also key for achieving Service User outcomes, which is reflected in the ER Program Logic presented on page 31. The survey and interview data show that referrals within an integrated service (internal) or in a service hub (co-located) are most effective. Where this is not possible, warm referrals within a trusted network of support are more effective than cold referrals leading to higher take-up and beneficial Service User outcomes. However, cold referrals are most common, pointing to a weakness in ER referral systems. This is because ER Providers do not operate or co-locate with interrelated services in many cases, nor do they have the case management capacity to provide warm referrals in many other cases. For mental illness support, which interviewees identified as one of the most difficult issues to deal with, ER Providers offer an integrated service only 23% of the time, warm referrals 34% of the time, and cold referrals 43% of the time. A focus on referral systems at the individual ER Provider level, and system level through a joined-up approach, might lead to better outcomes for Service Users. The program logic and theory of change for ER have been documented with input from the research findings and included in Section 4.3 on page 31. These show that ER helps people facing a financial crisis to meet their immediate needs, avoid further harm, and access a path to recovery. The research demonstrates that ER is fundamental to supporting vulnerable people in Australia and should therefore continue to be funded by government.
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Carney, Nancy, Tamara Cheney, Annette M. Totten, Rebecca Jungbauer, Matthew R. Neth, Chandler Weeks, Cynthia Davis-O'Reilly et al. Prehospital Airway Management: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), Juni 2021. http://dx.doi.org/10.23970/ahrqepccer243.

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Objective. To assess the comparative benefits and harms across three airway management approaches (bag valve mask [BVM], supraglottic airway [SGA], and endotracheal intubation [ETI]) by emergency medical services in the prehospital setting, and how the benefits and harms differ based on patient characteristics, techniques, and devices. Data sources. We searched electronic citation databases (Ovid® MEDLINE®, CINAHL®, the Cochrane Central Register of Controlled Trials, the Cochrane Database of Systematic Reviews, and Scopus®) from 1990 to September 2020 and reference lists, and posted a Federal Register notice request for data. Review methods. Review methods followed Agency for Healthcare Research and Quality Evidence-based Practice Center Program methods guidance. Using pre-established criteria, studies were selected and dual reviewed, data were abstracted, and studies were evaluated for risk of bias. Meta-analyses using profile-likelihood random effects models were conducted when data were available from studies reporting on similar outcomes, with analyses stratified by study design, emergency type, and age. We qualitatively synthesized results when meta-analysis was not indicated. Strength of evidence (SOE) was assessed for primary outcomes (survival, neurological function, return of spontaneous circulation [ROSC], and successful advanced airway insertion [for SGA and ETI only]). Results. We included 99 studies (22 randomized controlled trials and 77 observational studies) involving 630,397 patients. Overall, we found few differences in primary outcomes when airway management approaches were compared. • For survival, there was moderate SOE for findings of no difference for BVM versus ETI in adult and mixed-age cardiac arrest patients. There was low SOE for no difference in these patients for BVM versus SGA and SGA versus ETI. There was low SOE for all three comparisons in pediatric cardiac arrest patients, and low SOE in adult trauma patients when BVM was compared with ETI. • For neurological function, there was moderate SOE for no difference for BVM compared with ETI in adults with cardiac arrest. There was low SOE for no difference in pediatric cardiac arrest for BVM versus ETI and SGA versus ETI. In adults with cardiac arrest, neurological function was better for BVM and ETI compared with SGA (both low SOE). • ROSC was applicable only in cardiac arrest. For adults, there was low SOE that ROSC was more frequent with SGA compared with ETI, and no difference for BVM versus SGA or BVM versus ETI. In pediatric patients there was low SOE of no difference for BVM versus ETI and SGA versus ETI. • For successful advanced airway insertion, low SOE supported better first-pass success with SGA in adult and pediatric cardiac arrest patients and adult patients in studies that mixed emergency types. Low SOE also supported no difference for first-pass success in adult medical patients. For overall success, there was moderate SOE of no difference for adults with cardiac arrest, medical, and mixed emergency types. • While harms were not always measured or reported, moderate SOE supported all available findings. There were no differences in harms for BVM versus SGA or ETI. When SGA was compared with ETI, there were no differences for aspiration, oral/airway trauma, and regurgitation; SGA was better for multiple insertion attempts; and ETI was better for inadequate ventilation. Conclusions. The most common findings, across emergency types and age groups, were of no differences in primary outcomes when prehospital airway management approaches were compared. As most of the included studies were observational, these findings may reflect study design and methodological limitations. Due to the dynamic nature of the prehospital environment, the results are susceptible to indication and survival biases as well as confounding; however, the current evidence does not favor more invasive airway approaches. No conclusion was supported by high SOE for any comparison and patient group. This supports the need for high-quality randomized controlled trials designed to account for the variability and dynamic nature of prehospital airway management to advance and inform clinical practice as well as emergency medical services education and policy, and to improve patient-centered outcomes.
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Saville, Alan, und Caroline Wickham-Jones, Hrsg. Palaeolithic and Mesolithic Scotland : Scottish Archaeological Research Framework Panel Report. Society for Antiquaries of Scotland, Juni 2012. http://dx.doi.org/10.9750/scarf.06.2012.163.

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Why research Palaeolithic and Mesolithic Scotland? Palaeolithic and Mesolithic archaeology sheds light on the first colonisation and subsequent early inhabitation of Scotland. It is a growing and exciting field where increasing Scottish evidence has been given wider significance in the context of European prehistory. It extends over a long period, which saw great changes, including substantial environmental transformations, and the impact of, and societal response to, climate change. The period as a whole provides the foundation for the human occupation of Scotland and is crucial for understanding prehistoric society, both for Scotland and across North-West Europe. Within the Palaeolithic and Mesolithic periods there are considerable opportunities for pioneering research. Individual projects can still have a substantial impact and there remain opportunities for pioneering discoveries including cemeteries, domestic and other structures, stratified sites, and for exploring the huge evidential potential of water-logged and underwater sites. Palaeolithic and Mesolithic archaeology also stimulates and draws upon exciting multi-disciplinary collaborations. Panel Task and Remit The panel remit was to review critically the current state of knowledge and consider promising areas of future research into the earliest prehistory of Scotland. This was undertaken with a view to improved understanding of all aspects of the colonization and inhabitation of the country by peoples practising a wholly hunter-fisher-gatherer way of life prior to the advent of farming. In so doing, it was recognised as particularly important that both environmental data (including vegetation, fauna, sea level, and landscape work) and cultural change during this period be evaluated. The resultant report, outlines the different areas of research in which archaeologists interested in early prehistory work, and highlights the research topics to which they aspire. The report is structured by theme: history of investigation; reconstruction of the environment; the nature of the archaeological record; methodologies for recreating the past; and finally, the lifestyles of past people – the latter representing both a statement of current knowledge and the ultimate aim for archaeologists; the goal of all the former sections. The document is reinforced by material on-line which provides further detail and resources. The Palaeolithic and Mesolithic panel report of ScARF is intended as a resource to be utilised, built upon, and kept updated, hopefully by those it has helped inspire and inform as well as those who follow in their footsteps. Future Research The main recommendations of the panel report can be summarized under four key headings:  Visibility: Due to the considerable length of time over which sites were formed, and the predominant mobility of the population, early prehistoric remains are to be found right across the landscape, although they often survive as ephemeral traces and in low densities. Therefore, all archaeological work should take into account the expectation of Palaeolithic and Mesolithic ScARF Panel Report iv encountering early prehistoric remains. This applies equally to both commercial and research archaeology, and to amateur activity which often makes the initial discovery. This should not be seen as an obstacle, but as a benefit, and not finding such remains should be cause for question. There is no doubt that important evidence of these periods remains unrecognised in private, public, and commercial collections and there is a strong need for backlog evaluation, proper curation and analysis. The inadequate representation of Palaeolithic and Mesolithic information in existing national and local databases must be addressed.  Collaboration: Multi-disciplinary, collaborative, and cross- sector approaches must be encouraged – site prospection, prediction, recognition, and contextualisation are key areas to this end. Reconstructing past environments and their chronological frameworks, and exploring submerged and buried landscapes offer existing examples of fruitful, cross-disciplinary work. Palaeolithic and Mesolithic archaeology has an important place within Quaternary science and the potential for deeply buried remains means that geoarchaeology should have a prominent role.  Innovation: Research-led projects are currently making a substantial impact across all aspects of Palaeolithic and Mesolithic archaeology; a funding policy that acknowledges risk and promotes the innovation that these periods demand should be encouraged. The exploration of lesser known areas, work on different types of site, new approaches to artefacts, and the application of novel methodologies should all be promoted when engaging with the challenges of early prehistory.  Tackling the ‘big questions’: Archaeologists should engage with the big questions of earliest prehistory in Scotland, including the colonisation of new land, how lifestyles in past societies were organized, the effects of and the responses to environmental change, and the transitions to new modes of life. This should be done through a holistic view of the available data, encompassing all the complexities of interpretation and developing competing and testable models. Scottish data can be used to address many of the currently topical research topics in archaeology, and will provide a springboard to a better understanding of early prehistoric life in Scotland and beyond.
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