Thematische Bibliographien / Mice Reproduction

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Auswahl der wissenschaftlichen Literatur zum Thema „Mice Reproduction“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 20. Februar 2023

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Zeitschriftenartikel zum Thema "Mice Reproduction"

Lafaille, Marie, Patrick Gouat und Christophe Féron. „Efficiency of delayed reproduction in Mus spicilegus“. Reproduction, Fertility and Development 27, Nr. 3 (2015): 491. http://dx.doi.org/10.1071/rd13130.

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To cope with seasonally varying ecological constraints, some mammals temporally suppress breeding or delay their first reproduction. In field conditions, mound-building mice (Mus spicilegus) born in spring begin to reproduce when 2–3 months old, whereas individuals born at the end of summer delay their first reproduction for 6–8 months until the following spring. In order to test age effects on reproductive performance in M. spicilegus, sexually naïve mice were paired when 2–3 months old or at 6–8 months of age, and surveyed for reproduction. We show here that under laboratory conditions the aging of these mice does not impair their reproductive efficiency. Thus, the hypothesis of a lower reproductive potential in these relatively aged females seems to be contradicted. More surprisingly, the latency from pairing to the first reproduction was greater in the 2–3-month-old adults than in the delayed reproducers (6–8-month-old mice). Mound-building mice that are old enough to have overwintered do not suffer significant reproductive declines, but appear to reproduce as well and more quickly than younger first-time breeders.

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Munger, James C., und William H. Karasov. „Sublethal parasites in white-footed mice: impact on survival and reproduction“. Canadian Journal of Zoology 69, Nr. 2 (01.02.1991): 398–404. http://dx.doi.org/10.1139/z91-062.

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The potential impact of two parasites on the population density of host white-footed mice (Peromyscus leucopus) was assessed by measuring effects on survival and reproduction in field populations. Thirty-eight mice infected with larvae of the bot fly Cuterebra angustifrons had their larvae removed, another 41 mice remained infected, and 46 other mice were naturally uninfected during the experiment. No effect of bot larvae removal was detected on either survival (measured as attrition) or reproduction (measured as end of reproductive season). However, contrary to expectation, naturally infected mice had lower attrition and a marginally longer reproductive season than naturally uninfected mice. This latter result is probably an artifact, due to underlying differences between naturally infected and uninfected mice. Sixty-seven mice were experimentally infected with the tapeworm Hymenolepis citelli (64 mice were controls), but no effect was detected on attrition from the trappable population nor on the cessation of the reproductive season. Our results indicate that (i) these parasites are unlikely to have any effect on population density of white-footed mice, and (ii) it is potentially misleading to use "natural experiments" (comparison of naturally infected hosts with uninfected hosts) to study the impact of parasitic infection.

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Harini, C., S. B. Sainath und P. Sreenivasula Reddy. „Recovery of suppressed male reproduction in mice exposed to progesterone during embryonic development by testosterone“. REPRODUCTION 137, Nr. 3 (März 2009): 439–48. http://dx.doi.org/10.1530/rep-08-0438.

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The present study aimed to examine whether transplacental exposure to progesterone caused male reproductive abnormalities and whether the changes can be reversed after testosterone administration. Progesterone was injected to mice on day 1, 3, and 7 of pregnancy. The male pups (F1 generation) were allowed to grow for 50 days and assessed for reproductive performance. Gestational exposure to progesterone (7 mg/kg body weight) resulted in significant body weight gain with a decrease in reproductive tissue indices in mice. Total sperm count, viable sperm, and motile sperm decreased in experimental mice. Hypo-osmotic swelling test revealed that experimental mice sperm membrane integrity was severely altered. The activity levels of testicular steroidogenic marker enzymes (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase cluster (HSD3B) and hydroxysteroid (17-beta) dehydrogenase 1 (HSD17B)) decreased significantly in mice exposed to progesterone during embryonic development when compared with the controls. The levels of serum testosterone decreased with an increase in serum FSH and LH in mice exposed to progesterone during embryonic development. Prenatal exposure to progesterone caused significant reduction in the number of spermatozoa and increase in the lumen of seminiferous tubule. The experimental mice that cohabited with normal females showed fertility reduction. Administration of testosterone (4.16 mg/kg body weight) on postnatal day 20, 30, and 40 to progesterone-exposed prenates resulted in recovery of progesterone-induced suppressed male reproduction. It is suggested that the impairment of male reproduction in mice exposed to progesterone during embryonic development could be mediated through the inhibition of testosterone production. These results also indicate thatin uteroexposure to progesterone affects male reproduction and that supplementation of testosterone restores the suppressed male reproduction.

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Rollo, C. D., J. Rintoul und L. J. Kajiura. „Lifetime reproduction of giant transgenic mice: the energy stress paradigm“. Canadian Journal of Zoology 75, Nr. 8 (01.08.1997): 1336–45. http://dx.doi.org/10.1139/z97-758.

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Lifetime reproduction of female transgenic rat growth hormone (TRrGH) mice and their normal siblings was evaluated on a high-protein (38%) diet, a standard diet (23% protein), and the standard diet supplemented with sucrose cubes. Compared with those on the standard diet, normal mice fed the high-protein diet showed significant increases in litter size, number of litters, and lifetime fecundity. Number of litters and lifetime fecundity were also enhanced in normal mice fed sucrose. TRrGH mice showed no significant improvements in reproduction on the high-protein diet, but they were significantly smaller. Sucrose dramatically improved reproduction of TRrGH mice, with no reduction in mature mass. The percentage of fertile TRrGH mice increased from 45% on standard chow to 71% with sucrose. The number and size of litters of TRrGH mice also significantly increased with sucrose, mean lifetime fecundity doubling from 9 pups on standard food to 18 pups on sucrose. However, TRrGH mice did not attain the reproductive success of normal mice on any diet. These results suggest that TRrGH mice are energetically stressed by enforced channelling of energy into growth. An immense literature addresses infertility due to energy limitation and stress generally. We synthesize these aspects with growth hormone transgenesis to derive an integrated view of neuroendocrine energy regulation relevant to restoring fertility of transgenic GH animals.

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Yang, Jichun, Lihong Chen, Xiaoyan Zhang, Yunfeng Zhou, Dongjuan Zhang, Ming Huo und Youfei Guan. „PPARs and Female Reproduction: Evidence from Genetically Manipulated Mice“. PPAR Research 2008 (2008): 1–8. http://dx.doi.org/10.1155/2008/723243.

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Peroxisome proliferator-activated receptors (PPARs) are ligand-activated nuclear receptors controlling many important physiological processes, including lipid and glucose metabolism, energy homeostasis, inflammation, as well as cell proliferation and differentiation. In the past decade, intensive study of PPARs has shed novel insight into prevention and treatment of dyslipidemia, insulin resistance, and type 2 diabetes. Recently, a large body of research revealed that PPARs are also functionally expressed in reproductive organs and various parts of placenta during pregnancy, which strongly suggests that PPARs might play a critical role in reproduction and development, in addition to their central actions in energy homeostasis. In this review, we summarize recent findings elucidating the role of PPARs in female reproduction, with particular focus on evidence from gene knockout and transgenic animal model study.

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Reese, Jeff, Xuemei Zhao, Wen-Ge Ma, Naoko Brown, Timothy J. Maziasz und S. K. Dey. „Comparative Analysis of Pharmacologic and/or Genetic Disruption of Cyclooxygenase-1 and Cyclooxygenase-2 Function in Female Reproduction in Mice*“. Endocrinology 142, Nr. 7 (01.07.2001): 3198–206. http://dx.doi.org/10.1210/endo.142.7.8307.

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Abstract Cyclooxygenase (COX)-derived prostaglandins are critical in female reproduction. Gene targeting studies show that ovulation, fertilization, implantation, and decidualization are defective in COX-2 deficient mice. We used genetic and pharmacologic approaches to perturb COX function and examine the differential and synergistic effects of inhibition of COX-1, COX-2, or of both isoforms on reproductive outcomes during early pregnancy in mice. The results demonstrate that simultaneous inhibition of COX-1 and COX-2 produces more severe effects on early pregnancy events than inhibition of either isoform alone. The effects of pharmacological inhibition of COX-2 on female reproductive functions were less severe than the null mutation of the COX-2 gene. A combined approach showed that COX-2 inhibition in COX-1−/− mice induced complete reproductive failure, suggesting a lack of alternative sources of prostaglandin synthesis. This investigation raises caution regarding the indiscriminate use of COX inhibitors and shows for the first time the distinct and overlapping pathways of the cyclooxygenase systems in female reproduction.

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Harrington, Monica. „Common disinfectants impair reproduction in mice“. Lab Animal 43, Nr. 10 (19.09.2014): 335. http://dx.doi.org/10.1038/laban.635.

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Yang, Haoxuan, Izhar Hyder Qazi, Bo Pan, Christiana Angel, Shichao Guo, Jingyu Yang, Yan Zhang et al. „Dietary Selenium Supplementation Ameliorates Female Reproductive Efficiency in Aging Mice“. Antioxidants 8, Nr. 12 (11.12.2019): 634. http://dx.doi.org/10.3390/antiox8120634.

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Female reproductive (ovarian) aging is distinctively characterized by a markedly reduced reproductive function due to a remarkable decline in quality and quantity of follicles and oocytes. Selenium (Se) has been implicated in playing many important biological roles in male fertility and reproduction; however, its potential roles in female reproduction, particularly in aging subjects, remain poorly elucidated. Therefore, in the current study we used a murine model of female reproductive aging and elucidated how different Se-levels might affect the reproductive efficiency in aging females. Our results showed that at the end of an 8-week dietary trial, whole-blood Se concentration and blood total antioxidant capacity (TAOC) were significantly reduced in Se-deficient (0.08 mg Se/kg; Se-D) mice, whereas both of these biomarkers were significantly higher in inorganic (0.33 mg/kg; ISe-S) and organic (0.33 mg/kg; OSe-S) Se-supplemented groups. Similarly, compared to the Se-D group, Se supplementation significantly ameliorated the maintenance of follicles and reduced the rate of apoptosis in ovaries. Meanwhile, the rate of in vitro-produced embryos resulting from germinal vesicle (GV) oocytes was also significantly improved in Se-supplemented (ISe-S and OSe-S) groups compared to the Se-D mice, in which none of the embryos developed to the hatched blastocyst stage. RT-qPCR results revealed that mRNA expression of Gpx1, Gpx3, Gpx4, Selenof, p21, and Bcl-2 genes in ovaries of aging mice was differentially modulated by dietary Se levels. A considerably higher mRNA expression of Gpx1, Gpx3, Gpx4, and Selenof was observed in Se-supplemented groups compared to the Se-D group. Similarly, mRNA expression of Bcl-2 and p21 was significantly lower in Se-supplemented groups. Immunohistochemical assay also revealed a significantly higher expression of GPX4 in Se-supplemented mice. Our results reasonably indicate that Se deficiency (or marginal levels) can negatively impact the fertility and reproduction in females, particularly those of an advancing age, and that the Se supplementation (inorganic and organic) can substantiate ovarian function and overall reproductive efficiency in aging females.

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Hicks, Kristina L., Elysia Roche, James D. Wilkerson und Krista E. Lindstrom. „Effects of Maternal Fenbendazole on Litter Size, Survival Rate, and Weaning Weight in C57BL/6J Mice“. Journal of the American Association for Laboratory Animal Science 60, Nr. 6 (01.11.2021): 630–36. http://dx.doi.org/10.30802/aalas-jaalas-21-000056.

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Fenbendazole is a broad-spectrum benzimidazole commonly used in laboratory animal medicine as an anthelmintic for elimination of pinworms. This drug is generally regarded as safe, with minimal side effects. Some data in rodent species indicate multiple physiologic effects of fenbendazole, including changes in immune parameters and behavior, but no studies to date have evaluated possible effects on reproduction in mice. The purpose of the current study was to determine the effects of several treatment regimens of fenbendazole on reproductive parameters in C57BL/6J mice. Uninfected mice were given fenbendazole-treated feed continuously or every other week until pups were born or weaned. This treatment also was combined with environmental decontamination. No significant differences in litter size, survival rate, or weaning weight were detected between groups. Under the conditions of this study, fenbendazole treatment does not affect reproduction in C57BL/6J mice.

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Roy, Angshumoy, und Martin M. Matzuk. „Deconstructing mammalian reproduction: using knockouts to define fertility pathways“. Reproduction 131, Nr. 2 (Februar 2006): 207–19. http://dx.doi.org/10.1530/rep.1.00530.

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Reproduction is the sine qua non for the propagation of species and continuation of life. It is a complex biological process that is regulated by multiple factors during the reproductive life of an organism. Over the past decade, the molecular mechanisms regulating reproduction in mammals have been rapidly unraveled by the study of a vast number of mouse gene knockouts with impaired fertility. The use of reverse genetics to generate null mutants in mice through targeted disruption of specific genes has enabled researchers to identify essential regulators of spermatogenesis and oogenesis in vivo and model human disorders affecting reproduction. This review focuses on the merits, utility, and the variations of the knockout technology in studies of reproduction in mammals.

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Dissertationen zum Thema "Mice Reproduction"

Jackson, Claire. „Aspects of reproduction in the four-striped field mouse, Rhabdomys pumilio“. Thesis, Rhodes University, 2000. http://hdl.handle.net/10962/d1005319.

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Rhabdomys pumilio, in the Eastern Cape of South Africa, does not use short day length as an inhibitory cue for reproductive activity, and, despite previous records indicating that these mice are strictly seasonal in their reproduction, litters have been found during the winters of some years,both in the Eastern Cape and in the Western Cape. This led me to believe that the reproductive activity of Rhabdomys pumilio is more opportunistic and that the cue or cues used to control reproduction are less predictable and, or more variable than the photoperiod cue used by many seasonally reproducing rodents. Two experiments were conducted, investigating the influence of low ambient temperature (15⁰C)and reduced food availability on the reproductive activity of both male and female four striped field mice. Mice were maintained in one of four conditions (food restricted at 15⁰C, food restricted at 26⁰C, ad lib. food at 15⁰C, and ad lib. food at 26⁰C) for 4 (males) and 8 weeks (females)(photoperiod 12L:12D, humidity 40%). Results indicated that the males reduced their reproductive activity slightly when exposed to either low temperature or low food availability and that maximum inhibition of reproduction occurred when mice were exposed to both low temperature and low food availability. However, female reproductive activity was inhibited when exposed to low food availability, irrespective of the temperature. Both sexes of mice showed varying abilities to resist fat loss and, in the males, the size of the fat store had a significant effect on reproduction. This varying ability to resist fat loss could be related to levels of activity and in the females (where activity was quantified), high activity scores were significantly associated with reproductive inhibition. These results support the hypothesis that reproduction in Rhabdomys pumilio is opportunistic and controlled by the availability of energy. I propose that the females will be more sensitive to reproductive inhibition due to their far greater post-fertilization responsibilities, where the reproductive activity of the females is rapidly inhibited by a reduction in food availability, while the males are less readily inhibited by low food availability or low temperature, unless the change in the controlling factors is severe enough, or prolonged, at which stage their reproductive activity will cease. The significance of opportunistic reproduction in the seasonal but unpredictable climate of the study area is discussed.

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Cantrill, Steven. „The population dynamics of the house mouse (Mus domesticus) in a dual crop agricultural ecosystem“. Thesis, Queensland University of Technology, 1992.

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Thayer, Kristina A. „Prenatal exposure to low doses of estrogen : reproductive effects in male and female mice and implications for regulation of endocrine disrupting environmental chemicals /“. free to MU campus, to others for purchase, 1999. http://wwwlib.umi.com/cr/mo/fullcit?p9951127.

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Ruhlen, Rachel L. „Diets, estrogen environment of the fetus, and development of the reproductive tract and other systems /“. free to MU campus, to others for purchase, 2003. http://wwwlib.umi.com/cr/mo/fullcit?p3091965.

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Agyeman, Duah Osei. „Effect of litter size manipulation on lactation, and offspring's reproduction and susceptibility to obesity“. Thesis, Available from the University of Aberdeen Library and Historic Collections Digital Resources. Restricted ; no access until January 30, 2010. Online version available for University members only until May 11, 2010, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?application=DIGITOOL-3&owner=resourcediscovery&custom_att_2=simple_viewer&pid=26022.

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Gamo, Yuko. „Effects of reproduction on body temperature and physical activity“. Thesis, University of Aberdeen, 2009. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=130928.

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Daily changes in body temperature as well as physical activeness from mating to pregnancy were illustrated in MF1 mice. Body temperature and physical activity gradually declined as pregnancy advanced while energy intake and body mass increased in late pregnancy. Diurnal and nocturnal locomotor activity and body temperature were significantly lower in late pregnancy than in non-reproductive and mating phases. Despite low physical activity, inactive body temperature was relatively high through late pregnancy. This suggests that pregnant mice tend to increase thermogenesis against a drop of body temperature. Energy intake increased remarkably after parturition and reached a plateau in late lactation suggesting a limit of energy intake. Litter size and litter mass significantly influenced maternal energy intake and body mass (P<0.05). However, daily pup mass gain declined at the peak lactation when maternal energy intake was limited. Body temperature rose sharply after parturition. Body temperature during the day considerably increased. Consequently, lactating mice faced a constantly high body temperature through the day despite lower activity levels. There were no trends that litter size and litter mass stimulated maternal body temperature and physical activity on average through lactation. Body temperature during suckling inside the nest increased towards the end of suckling. However, no significant increase in body temperature was found between 20 and 1 minutes before terminating suckling bouts. Dams that raised larger litters encountered higher body temperature while suckling inside the nest, suggesting that suckling offspring considerably contributed to heat retention in mothers. Suckling offspring appeared to prevent mothers from releasing cumulative heat, although the significance of suckling behaviour on overheating was smaller than that of metabolic heat generation.

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Jackson, Claire. „Studies of the environmental and endocrine control of reproduction in the four striped field mouse, Rhabdomys pumilio“. Thesis, Rhodes University, 2003. http://hdl.handle.net/10962/d1005465.

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Previous studies of the control of reproduction in Rhabdomys pumilio have shown that day length alone does not inhibit spermatogenesis, that a reduction in food availability and ambient temperature results in an inhibition of gametogenesis, that females are more susceptible to inhibition than are males, and that mice that are able to maintain a body fat store in the face of an energetic challenge, are less likely to show reproductive inhibition than those that lose their fat store. In the present study, field and laboratory experiments were conducted to examine the effects of winter food supplementation on reproduction and population dynamics, and the effects of exogenous GnRH, leptin and mercaptoacetate (MA) on reproductive activity of Rhabdomys pumilio exposed to an energetic challenge. In the field food supplementation experiments in Thomas Baines Nature Reserve (2000, 2001), there was no winter inhibition of reproduction and provision of supplementary food had little effect. While at Mountain Zebra National Park (2002) winter was harsher, females became reproductively inactive, spermatogenesis continued and the provision of extra food resulted in higher rates of individual growth and larger reproductive organs. Treatment of mice that had been exposed to a prolonged energetic challenge, with exogenous GnRH (1µg/mouse/treatment) resulted in an increase in the masses of the testes and epididymides, and in the activity of the reproductive organs. Treatment with exogenous leptin (40µg/mouse/treatment), concurrently with an energetic challenge, countered the negative effects of the energetic challenge, and treated males had larger reproductive organs. MA (600µmol/kg body mass), given concurrently with an energetic challenge, did not inhibit fat metabolism, although the high-fat diet countered the effects of the energetic challenge. Results suggest that the first response of male Rhabdomys pumilio to an energetic challenge is a reduction in the size of the reproductive organs, without an inhibition of spermatogenesis. It is likely that this effect is mediated via white fat and leptin, and leptin’s influence on the hypothalamic-pituitary-gonad axis. Results of the study support the suggestion that females are more sensitive to reproductive inhibition than males and that reproduction in Rhabdomys pumilio is truly opportunistic.

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Bander, S. A. A. „Pre-zygotic interactions in mice : A genetic analysis“. Thesis, University of Essex, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.380568.

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Shukri, N. M. „Genetic studies of male reproductive characteristics in mice“. Thesis, University of Essex, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383426.

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Gray, Janine. „The effect of photoperiod on some aspects of reproduction in a Southern African rodent : the pouched mouse (Saccostomus Campestris)“. Thesis, Rhodes University, 2001. http://hdl.handle.net/10962/d1005361.

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The pouched mouse, Saccostomus campestris is widely distributed south of the Sahara, inhabiting both subtropical and tropical latitudes and a number of different biotic zones, where it breeds seasonally. In North temperate latitudes, reproduction in small mammals is controlled by photoperiod however this cue becomes less influential as latitude decreases towards the equator. The aim of the present study is to establish the role of photoperiod in the environmental control of reproduction in a seasonally breeding small mammal at low latitudes in a highly unpredictable environment. Spermatogenesis of domesticated and Fl-generation pouched mice was not inhibited by short daylength while decreasing daylength significantly affected the oestrous cycle of adult domesticated female pouched mice. Photoperiod had little effect on the oestrous cycle of F I-generation females while a possible inherent circannual endogenous rhythm controlled inhibition of reproduction in these females. Body mass of male and female juvenile pouched mice was consistently lower in short daylength and in juvenile female pouched mice the onset of fertility may be weight-dependent. The attainment of sexual maturity of domesticated and FIlF2-generation females was retarded but not halted in short daylength and females in long daylength reached puberty 7.8 - 10.2 days earlier. Short daylength also lengthened the interval between vaginal perforation and first oestrus. Puberty in juvenile females was age-dependent as both domesticated and FIlF2-generation males attained puberty at 50 days of age, although fewer males were fertile in long daylength than short daylength. Although litter size of pouched mice was smaller in short daylength for both domesticated and wildcaught females this was not due to a reduction in the ovulation rate. Domesticated females had significantly larger litters than wild-caught females. Male and female pouched mice have evolved different reproductive strategies as males become sexually mature at the same age irrespective of photoperiod and remain fertile throughout the year. In contrast, females tend to be more complex as juveniles delay reproductive maturity and adults become nonreproductive in short daylength. However, in the presence of a fertile male and if environmental conditions are favourable, in short daylength, females can become reproductively active within approximately 3 days. Thus, although the pouched mouse has adopted a purely opportunistic reproductive strategy, vestiges of photoresponsiveness are still present in the female. The seasonality exhibited in the wild is therefore due to the female. Pouched mice live in a highly unpredictable environment so the sole use of photoperiod to regulate reproduction would be disadvantageous.

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Bücher zum Thema "Mice Reproduction"

The mouse: Its reproduction and development. Oxford [England]: Oxford University Press, 1990.

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Viavant, Timothy Roland. Hatching success of lake trout eggs in artificial incubation substrates in Harding and Seven Mile Lakes. Anchorage: Alaska Dept. of Fish and Game, Division of Sport Fish, Research and Technical Services, 1998.

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Kelley, Mike. Mike Kelley: Framed and frame (miniature reproduction "Chinatown wishing well" built by Mike Kelley after "Miniature reproduction 'Seven star cavern' built by Prof. H.K. Lu")" : test room containing multiple stimuli known to elicit curiosity and manipulatory responses. Grenoble: Magasin, 1999.

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Ruth, Heller. La razón de ser de una flor. New York: Scholastic, 1993.

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Ruth, Heller. The reason for a flower. New York: Scholastic, 1988.

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A ton of spirit: Australian centenarians. North Sydney, N.S.W: Allen & Unwin Australia, 1990.

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Ensminger, Amanda Lynn. The effects of kinship and tolerance among wild male house mice (Mus musculus) on female reproductive success and odor preferences. 2002.

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Rugh, Roberts. The Mouse: Its Reproduction and Development (Oxford Science Publications). Oxford University Press, USA, 1990.

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Astrahantseff, Kathy N. Interactions between cultured mouse uterine epithelial and stromal cells during estrogen-induced proliferation. 1992.

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Mutter sag, wer macht die Kinder? Mosaik, 1992.

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Buchteile zum Thema "Mice Reproduction"

Gore, Andrea C. „GnRH Mutants and Transgenic Mice“. In GnRH: The Master Molecule of Reproduction, 205–15. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4757-3565-9_10.

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Bikoff, Elizabeth K., und Elizabeth J. Robertson. „Developmental Regulation of MHC Class I Gene Expression in Mice“. In Immunobiology of Reproduction, 201–13. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4613-8422-9_14.

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Drickamer, Lee C. „Chemosignals and Reproduction in Adult Female House Mice“. In Chemical Signals in Vertebrates 6, 245–51. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9655-1_38.

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Sugimoto, Y., E. Segi, K. Tsuboi, A. Ichikawa und S. Narumiya. „Female Reproduction in Mice Lacking the Prostaglandin F Receptor“. In Advances in Experimental Medicine and Biology, 317–21. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-4871-3_39.

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Ito, Chizuru, Kenji Yamatoya und Kiyotaka Toshimori. „Equatorin-Related Subcellular and Molecular Events During Sperm Priming for Fertilization in Mice“. In Sexual Reproduction in Animals and Plants, 85–95. Tokyo: Springer Japan, 2014. http://dx.doi.org/10.1007/978-4-431-54589-7_7.

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Yoshimura, H. „Studies Contrasting Drug Effects on Reproduction Induced Agonistic Behaviour in Male and Female Mice“. In Topics in the Neurosciences, 94–109. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3359-0_6.

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Clark, D. A., D. K. Banwatt, J. Manuel, G. Fulop und B. A. Croy. „Scid Mice in Reproductive Biology“. In Current Topics in Microbiology and Immunology, 227–34. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74974-2_27.

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Kurpisz, Maciej. „Differences in Antisperm Humoral Responses in Pre-Pubertal Boys with Gonadal Failure and in SCID Mice“. In Reproductive Immunology, 256–63. Dordrecht: Springer Netherlands, 1999. http://dx.doi.org/10.1007/978-94-011-4197-0_25.

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O’Neill, Chris, Robert Lindeman, Cynthia Roberts, Ron Trent, Urszula Kryzminska und Janice Lutjena. „The Feasibility of Preimplantation-Embryo Biopsy and Genetic Screening for Prenatal Diagnosis: Studies with Mice“. In Advances in Assisted Reproductive Technologies, 903–17. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0645-0_93.

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Mangues, Ramon, Irving Seidman, Angel Pellicer und Jon W. Gordon. „MMTV/N-ras Transgenic Mice as a Model for Altered Capacitation Male Sterility and Tumorigenesis“. In Advances in Assisted Reproductive Technologies, 939–57. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0645-0_96.

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Konferenzberichte zum Thema "Mice Reproduction"

Djati, Muhammad Sasmito. „Alternative formulations of E. scaber and S. androgynous extracts as immunomodulatory agents for suppression of bacterial infection in pregnant mice: A case of traditional herbal formulas in reproduction“. In THE 9TH INTERNATIONAL CONFERENCE ON GLOBAL RESOURCE CONSERVATION (ICGRC) AND AJI FROM RITSUMEIKAN UNIVERSITY. Author(s), 2018. http://dx.doi.org/10.1063/1.5061908.

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„The Effects of Aloe vera Extract on Reproductive Parameters in Mice“. In International Conference on Biological, Environment and Food Engineering. International Institute of Chemical, Biological & Environmental Engineering, 2014. http://dx.doi.org/10.15242/iicbe.c814052.

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Li, Zhen. „Influence of estrogen receptor α phosphorylation at serine 309 on male reproductive function of mice“. In 15th International Congress of Histochemistry and Cytochemistry. Istanbul: LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.op-03.

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Kimoto, Natsumi, Hiroaki Hayashi, Takashi Asahara, Emi Tomita, Sota Goto, Yuki Kanazawa, Shuichiro Yamamoto, Masahiro Okada und Masashi Yamasaki. „Reproduction of response functions of a multi-pixel-type energy-resolved photon counting detector while taking into consideration interaction of X-rays, charge sharing and energy resolution“. In 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). IEEE, 2018. http://dx.doi.org/10.1109/nssmic.2018.8824417.

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Cajka, Tomas, Jiri Hricko, Lucie Rudl Kulhava, Michaela Novakova, Michaela Paucova und Ondrej Kuda. „MetaboAtlas21: A comprehensive metabolome and lipidome atlas of mouse tissues and biofluids“. In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/mzeg6052.

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Here, we present a specific atlas of mouse metabolome and lipidome (MetaboAtlas21) in the context of systemic energy balance (chow diet) and under chronic nutrient stress (high-fat diet). Male mice were fed a control (chow) diet for 2 months or a high-fat diet for 2 months and 10 months. Urine, plasma, feces, and 18 different tissues were collected from each animal for metabolomics and lipidomics analysis. These matrices cover digestive, excretory, respiratory, reproductive, endocrine, muscular, cardiovascular, and nervous systems. Also, chow and high-fat diet feeds were analyzed along with quality control human plasma/serum materials (NIST SRM 1950 plasma, Merck S1-100ML serum, Sigma–Aldrich S7023 serum). In total, 408 samples were included in this study. An “all-in-one” extraction protocol LIMeX using methyl tert-butyl ether, methanol, and water was used to isolate metabolite fractions and analyzed using a multiplatform LC-MS-based approach (7 platforms for non-fat tissues and biofluids; 8 platforms for adipose tissues). Raw data files were processed using MS-DIAL 4. Metabolites were annotated using in-house retention time–m/z library and using MS/MS libraries available from commercial and open sources (NIST20, MassBank, MoNA). Lipids were annotated using LipidBlast in MS-DIAL. Ultimately, we annotated over 3,000 unique polar metabolites and complex lipids. To better understand the structure of generated data, we provide a user-friendly data visualization tool (metaboatlas21.metabolomics.fgu.cas.cz) to easily access and analyze the different combinations of tissues and biofluids in response to the metabolic challenge (NIST20, MassBank, MoNA). Lipids were annotated using LipidBlast in MS-DIAL. Ultimately, we annotated over 3,000 unique polar metabolites and complex lipids. To better understand the structure of generated data, we provide a user-friendly data visualization tool (metaboatlas21.metabolomics.fgu.cas.cz) to easily access and analyze the different combinations of tissues and biofluids in response to the metabolic challenge.

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Berichte der Organisationen zum Thema "Mice Reproduction"

Mast, T. J., P. L. Hackett, J. R. Decker, R. B. Westerberg, L. B. Sasser, B. J. McClanahan, R. L. Rommereim und J. J. Evanoff. Inhalation reproductive toxicology studies: Sperm morphology study of n-hexane in B6C3F1 mice: Final report. Office of Scientific and Technical Information (OSTI), August 1988. http://dx.doi.org/10.2172/6800315.

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Mast, T. J., R. L. Rommereim, J. J. Evanoff, L. B. Sasser, J. R. Decker, K. H. Stoney, R. J. Weigel und R. B. Westerberg. Inhalation reproductive toxicology studies: Male dominant lethal study of n-hexane in Swiss (CD-1) mice: Final report. Office of Scientific and Technical Information (OSTI), August 1988. http://dx.doi.org/10.2172/6861431.

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Ficht, Thomas, Gary Splitter, Menachem Banai und Menachem Davidson. Characterization of B. Melinensis REV 1 Attenuated Mutants. United States Department of Agriculture, Dezember 2000. http://dx.doi.org/10.32747/2000.7580667.bard.

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Brucella Mutagenesis (TAMU) The working hypothesis for this study was that survival of Brucella vaccines was directly related to their persistence in the host. This premise is based on previously published work detailing the survival of the currently employed vaccine strains S19 and Rev 1. The approach employed signature-tagged mutagenesis to construct mutants interrupted in individual genes, and the mouse model to identify mutants with attenuated virulence/survival. Intracellular survival in macrophages is the key to both reproductive disease in ruminants and reticuloendothelial disease observed in most other species. Therefore, the mouse model permitted selection of mutants of reduced intracellular survival that would limit their ability to cause reproductive disease in ruminants. Several classes of mutants were expected. Colonization/invasion requires gene products that enhance host-agent interaction or increase resistance to antibacterial activity in macrophages. The establishment of chronic infection requires gene products necessary for intracellular bacterial growth. Maintenance of chronic infection requires gene products that sustain a low-level metabolism during periods characterized little or no growth (1, 2). Of these mutants, the latter group was of greatest interest with regard to our originally stated premise. However, the results obtained do not necessarily support a simplistic model of vaccine efficacy, i.e., long-survival of vaccine strains provides better immunity. Our conclusion can only be that optimal vaccines will only be developed with a thorough understanding of host agent interaction, and will be preferable to the use of fortuitous isolates of unknown genetic background. Each mutant could be distinguished from among a group of mutants by PCR amplification of the signature tag (5). This approach permitted infection of mice with pools of different mutants (including the parental wild-type as a control) and identified 40 mutants with apparently defective survival characteristics that were tentatively assigned to three distinct classes or groups. Group I (n=13) contained organisms that exhibited reduced survival at two weeks post-infection. Organisms in this group were recovered at normal levels by eight weeks and were not studied further, since they may persist in the host. Group II (n=11) contained organisms that were reduced by 2 weeks post infection and remained at reduced levels at eight weeks post-infection. Group III (n=16) contained mutants that were normal at two weeks, but recovered at reduced levels at eight weeks. A subset of these mutants (n= 15) was confirmed to be attenuated in mixed infections (1:1) with the parental wild-type. One of these mutants was eliminated from consideration due to a reduced growth rate in vitro that may account for its apparent growth defect in the mouse model. Although the original plan involved construction of the mutant bank in B. melitensis Rev 1 the low transformability of this strain, prevented accumulation of the necessary number of mutants. In addition, the probability that Rev 1 already carries one genetic defect increases the likelihood that a second defect will severely compromise the survival of this organism. Once key genes have been identified, it is relatively easy to prepare the appropriate genetic constructs (knockouts) lacking these genes in B. melitensis Rev 1 or any other genetic background. The construction of "designer" vaccines is expected to improve immune protection resulting from minor sequence variation corresponding to geographically distinct isolates or to design vaccines for use in specific hosts. A.2 Mouse Model of Brucella Infection (UWISC) Interferon regulatory factor-1-deficient (IRF-1-/- mice have diverse immunodeficient phenotypes that are necessary for conferring proper immune protection to intracellular bacterial infection, such as a 90% reduction of CD8+ T cells, functionally impaired NK cells, as well as a deficiency in iNOS and IL-12p40 induction. Interestingly, IRF-1-/- mice infected with diverse Brucella abortus strains reacted differently in a death and survival manner depending on the dose of injection and the level of virulence. Notably, 50% of IRF-1-/- mice intraperitoneally infected with a sublethal dose in C57BL/6 mice, i.e., 5 x 105 CFU of virulent S2308 or the attenuated vaccine S19, died at 10 and 20 days post-infection, respectively. Interestingly, the same dose of RB51, an attenuated new vaccine strain, did not induce the death of IRF-1-/- mice for the 4 weeks of infection. IRF-1-/- mice infected with four more other genetically manipulated S2308 mutants at 5 x 105 CFU also reacted in a death or survival manner depending on the level of virulence. Splenic CFU from C57BL/6 mice infected with 5 x 105 CFU of S2308, S19, or RB51, as well as four different S2308 mutants supports the finding that reduced virulence correlates with survival Of IRF-1-/- mice. Therefore, these results suggest that IRF-1 regulation of multi-gene transcription plays a crucial role in controlling B. abortus infection, and IRF-1 mice could be used as an animal model to determine the degree of B. abortus virulence by examining death or survival. A3 Diagnostic Tests for Detection of B. melitensis Rev 1 (Kimron) In this project we developed an effective PCR tool that can distinguish between Rev1 field isolates and B. melitensis virulent field strains. This has allowed, for the first time, to monitor epidemiological outbreaks of Rev1 infection in vaccinated flocks and to clearly demonstrate horizontal transfer of the strain from vaccinated ewes to unvaccinated ones. Moreover, two human isolates were characterized as Rev1 isolates implying the risk of use of improperly controlled lots of the vaccine in the national campaign. Since atypical B. melitensis biotype 1 strains have been characterized in Israel, the PCR technique has unequivocally demonstrated that strain Rev1 has not diverted into a virulent mutant. In addition, we could demonstrate that very likely a new prototype biotype 1 strain has evolved in the Middle East compared to the classical strain 16M. All the Israeli field strains have been shown to differ from strain 16M in the PstI digestion profile of the omp2a gene sequence suggesting that the local strains were possibly developed as a separate branch of B. melitensis. Should this be confirmed these data suggest that the Rev1 vaccine may not be an optimal vaccine strain for the Israeli flocks as it shares the same omp2 PstI digestion profile as strain 16M.

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Itinéraires thérapeutiques des adolescentes pendant la grossesse, l'accouchement et la période post-partum dans la zone d'intervention du projet. Population Council, 2009. http://dx.doi.org/10.31899/pgy20.1005.

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Le Population Council a réalisé une étude sur « les itinéraires thérapeutiques des adolescentes pendant la grossesse, l’accouchement et la période post-partum » dans cinq régions du Burkina Faso. Il s’agissait d’une étude qualitative, exploratoire qui a permis d’identifier et de décrire les itinéraires thérapeutiques des adolescentes en grossesse et post-partum en vue de déceler les obstacles liés à la fréquentation des centres de santé dans le suivi de la grossesse, de l’accouchement assisté et des soins aux nouveau-nés. Les résultats de l’étude montrent que, d’une manière générale, les adolescentes mariées ou non ont recours aux soins traditionnels à domicile par l’utilisation de plantes et/ou décoctions et ne se rendent au centre de santé qu’en cas de non satisfaction. De par l’intérêt et l’engouement de la population enquêtée pour le sujet, il apparaît que le contexte social est favorable à la mise en œuvre d’activités sur la santé reproductive en direction des différents groupes cibles. Les besoins à satisfaire sont réels et manifestes sur le terrain et des actions concrètes sont attendues en vue d’améliorer les conditions de vie des adolescentes, des adolescentes en grossesse et des post-partum.

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