Thematische Bibliographien / Melanocyte keratinocyte transplantation

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  1. Zeitschriftenartikel
  2. Dissertationen

Auswahl der wissenschaftlichen Literatur zum Thema „Melanocyte keratinocyte transplantation“

Autor: Grafiati
Veröffentlicht am 1. Juli 2021
Zuletzt aktualisiert am 8. Februar 2022

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Zeitschriftenartikel zum Thema "Melanocyte keratinocyte transplantation"

1

Mulekar, SanjeevV, Ahmed Al Issa und Abdullah Al Eisa. „Nevus depigmentosus treated by melanocyte-keratinocyte transplantation“. Journal of Cutaneous and Aesthetic Surgery 4, Nr. 1 (2011): 29. http://dx.doi.org/10.4103/0974-2077.79185.

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2

Mulekar, SanjeevV. „Melanocyte-keratinocyte transplantation procedure: A few insights“. Indian Journal of Dermatology, Venereology, and Leprology 82, Nr. 1 (2016): 13. http://dx.doi.org/10.4103/0378-6323.172904.

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3

Mulekar, Sanjeev V. „Melanocyte-keratinocyte cell transplantation for stable vitiligo“. International Journal of Dermatology 42, Nr. 2 (Februar 2003): 132–36. http://dx.doi.org/10.1046/j.1365-4362.2003.01628.x.

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MULEKAR, SANJEEV V., BASSEL GHWISH, AHMED AL ISSA und ABDULLAH AL EISA. „Melanocyte–Keratinocyte Transplantation for Postdiscoid Lupus Erythematosus Depigmentation“. Dermatologic Surgery 34, Nr. 2 (Februar 2008): 261–63. http://dx.doi.org/10.1097/00042728-200802000-00023.

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5

MULEKAR, SANJEEV V., BASSEL GHWISH, AHMED AL ISSA und ABDULLAH AL EISA. „Melanocyte-Keratinocyte Transplantation for Postdiscoid Lupus Erythematosus Depigmentation“. Dermatologic Surgery 34, Nr. 2 (21.12.2007): 261–63. http://dx.doi.org/10.1111/j.1524-4725.2007.34053.x.

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6

Mulekar, Sanjeev V., Ahmed Issa, Abdullah Eisa und Marwan Asaad. „Genital Vitiligo Treated by Autologous, Noncultured Melanocyte-Keratinocyte Cell Transplantation“. Dermatologic Surgery 31, Nr. 12 (Dezember 2005): 1737–40. http://dx.doi.org/10.2310/6350.2005.31324.

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7

Isedeh, Prescilia, Ahmed Al Issa, Henry W. Lim, Smita S. Mulekar und Sanjeev V. Mulekar. „Uncommon Responses of Segmental Vitiligo to Melanocyte-Keratinocyte Transplantation Procedure“. Journal of Cutaneous Medicine and Surgery 19, Nr. 2 (März 2015): 177–81. http://dx.doi.org/10.2310/7750.2014.14061.

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Background Patients with segmental vitiligo (SV), unlike those with nonsegmental vitiligo (NSV), have a more predictable course and are more responsive to surgery. Objective To report 10 patients with SV treated with the melanocyte-keratinocyte transplantation procedure (MKTP), who responded with unusual responses not previously reported in the literature. Methods This is a retrospective, observational study that reports 10 patients with SV who underwent the MKTP between May 2003 and May 2012. Results Two patients had successful repigmentation after split-thickness skin grafting after failure of the MKTP. Two patients developed a hypopigmented ring at a margin of the MKTP-treated area. One patient had complete repigmentation after a second MKTP. Two patients developed koebnerization of the recipient site. Three patients developed new vitiligo patches in previously unaffected areas after the MKTP. Conclusions Uncommon and even suboptimal responses can occur following the MKTP in SV patients. There is a need for studies to provide better understanding and outcomes for SV patients undergoing the MKTP.
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8

Mulekar, Sanjeev V., Ahmed Al Issa, Abdullah Al Eisa und Marwan Asaad. „Genital Vitiligo Treated by Autologous, Noncultured Melanocyte-Keratinocyte Cell Transplantation“. Dermatologic Surgery 31, Nr. 12 (Dezember 2005): 1737–40. http://dx.doi.org/10.1097/00042728-200512000-00024.

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9

Rawal, RC, Swati Rastogi, Puneet Goyal, Kanu Mangla, Neel Bhavsar und Himanshu Patel. „Study of transplantation of melanocyte keratinocyte suspension in treatment of vitiligo“. Indian Journal of Dermatology 51, Nr. 2 (2006): 142. http://dx.doi.org/10.4103/0019-5154.26941.

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10

Abdo Aguiar, Lara Silveira, Rita de Cássia Rossini, Lismary Aparecida de Forville Mesquita und Gerson Dellatorre. „Subacute cutaneous lupus erythematosus leukoderma treated with melanocyte‐keratinocyte transplantation procedure“. Journal of Cosmetic Dermatology 18, Nr. 6 (April 2019): 1733–36. http://dx.doi.org/10.1111/jocd.12942.

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Dissertationen zum Thema "Melanocyte keratinocyte transplantation"

1

Ahmed, Refat Maggi. „Improving the Success of Melanocyte Keratinocyte Transplantation Surgery in Vitiligo; The Role of JAK Inhibitors, and Ablative Laser Resurfacing“. eScholarship@UMMS, 2021. https://escholarship.umassmed.edu/gsbs_diss/1143.

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The Melanocyte Keratinocyte Transplantation Procedure (MKTP) is an effective surgical replacement of lost melanocytes in recalcitrant vitiligo and pigmentary skin disorders. However, it is only effective in stable vitiligo lesions because active autoimmunity destroys the newly transplanted melanocytes. Despite careful selection of candidates based on the reported clinical stability, the success of the procedure is still unpredictable. MKTP candidates with non-segmental, segmental, and mixed vitiligo, as well as hypopigmented scars and Piebaldism patients were enrolled to our studies. Our aim was first, to investigate the possible immunological mechanisms responsible for the unpredictable post- transplantation outcomes, including T cell subsets and inflammatory chemokines, by correlating these biomarkers with clinical phenotypes, duration of stability, and surgical outcomes. We used suction blister biopsy, a minimally invasive technique that we developed to sample human skin. Moreover, we quantified transplanted melanocytes in the suspension using flow cytometry. Following MKTP, we corelated these biomarkers to the repigmentation score. We found that CD8+ T cells remain in some clinically stable vitiligo lesions, correlate negatively with the post-surgical score of repigmentation, and inversely impact the durability of the responses. Interestingly, the number of transplanted melanocytes in the suspension and the duration of stability do not have prognostic roles. Based on our findings and in a second group of patients, we suppressed the activity of T cells to enhance the outcomes of MKTP. We used Ruxolitinib, JAK1/2 inhibitor, in a triple blinded randomized controlled within subject study, in comparison with Tacrolimus (a calcineurin inhibitor and the standard of care treatment in vitiligo) as well as placebo control. We found lower T cell infiltrate, lower chemokines, and better skin repigmentation in lesions treated with MKTP plus Ruxolitinib or Tacrolimus than in lesions treated with MKTP plus placebo. Lastly, we compared two different types of laser in preparation of the recipient skin for MKTP - ablative versus fractional Er:YAG laser. We found that the ablative laser is combined with minimal CD8+ T cell epidermal infiltrate and superior repigmentation score in comparison to more infiltrate and lower repigmentation score with the fractional laser. Taken together, these results from our studies provide novel insight to predict the optimal surgical candidates and will improve surgical outcomes. It advances the treatment of vitiligo by uncovering the impact of autoimmunity on the success of repigmentation and discovering new approaches to optimize the surgical treatment options in patients with vitiligo and pigmentary skin disorders.
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2

Liu, Tsung-Hsun, und 劉琮勛. „In vivo modification of pigmentation on nude mice by transplantation of tissue-engineered skin substitutes based on human melanocytes and keratinocytes“. Thesis, 2008. http://ndltd.ncl.edu.tw/handle/70929336940138135829.

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