Zeitschriftenartikel: „Measurement of blood cholesterol“

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Tobert, J. A. „Blood cholesterol measurement in young adults“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 936b—936. http://dx.doi.org/10.1001/jama.270.8.936b.

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Lane, D. M. „Blood cholesterol measurement in young adults“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 936c—936. http://dx.doi.org/10.1001/jama.270.8.936c.

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Tobert, Jonathan A. „Blood Cholesterol Measurement in Young Adults“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 936. http://dx.doi.org/10.1001/jama.1993.03510080040016.

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Lane, Daniel M. „Blood Cholesterol Measurement in Young Adults“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 936. http://dx.doi.org/10.1001/jama.1993.03510080040017.

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5

Lewis, Carol. „Blood Cholesterol Measurement in Young Adults“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 936. http://dx.doi.org/10.1001/jama.1993.03510080040018.

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6

Weissfeld, Joel L., und James J. Holloway. „Precision of blood cholesterol measurement and high blood cholesterol case-finding and treatment“. Journal of Clinical Epidemiology 45, Nr. 9 (September 1992): 971–84. http://dx.doi.org/10.1016/0895-4356(92)90113-2.

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7

Hulley, Stephen B. „Blood Cholesterol Measurement in Young Adults-Reply“. JAMA: The Journal of the American Medical Association 270, Nr. 8 (25.08.1993): 937. http://dx.doi.org/10.1001/jama.1993.03510080040019.

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8

Lee, Sang-Ah, Wanqing Wen, Yong-Bing Xiang, Sergio Fazio, MacRae F. Linton, Qiuyin Cai, Dake Liu, Wei Zheng und Xiao-Ou Shu. „Stability and Reliability of Plasma Level of Lipid Biomarkers and Their Correlation with Dietary Fat Intake“. Disease Markers 24, Nr. 2 (2008): 73–79. http://dx.doi.org/10.1155/2008/347817.

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The reliability and stability of plasma lipid biomarkers and their association with dietary fat intake were evaluated among 48 subjects who were randomly chosen from the participants of a validation study of the population-based cohort, the Shanghai Men's Health Study (SMHS). Four spot blood samples, one taken each season, were measured for total cholesterol, triglyceride, HDL-cholesterol, and LDL-cholesterol levels. The reliability and stability of these measurements were assessed by intraclass correlation coefficients (ICC) and by the correlations between a randomly chosen measurement with the mean of measurements across seasons using a bootstrap approach. The median levels for total cholesterol, triglycerides, HDL-cholesterol, and LDL-cholesterol were 177.5, 164.5, 41.0, and 102.5 (mg/dl), respectively. The ICCs of the biomarkers ranged from 0.58 (LDL-cholesterol) to 0.83 (HDL-cholesterol). The correlation between randomly chosen spot measurements and the mean measurement were 0.91, 0.86, 0.93, and 0.83 for total cholesterol, triglycerides, HDL-cholesterol, and LDL-cholesterol, respectively. The correlations of lipid biomarkers with dietary fat intake and other lifestyle factors were comparable to other previous reports. In conclusion, this study suggests that measurements of lipid biomarkers from a single spot blood sample are a good representation of the average blood levels of these biomarkers in the study population and could be a useful tool for epidemiological studies.

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Hyman, David J., Gilles Paradis und June A. Flora. „A Comparison of Participants and Nonparticipants in a Worksite Cholesterol Screening“. American Journal of Health Promotion 7, Nr. 2 (November 1992): 137–41. http://dx.doi.org/10.4278/0890-1171-7.2.137.

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Purpose. The purpose of this study is to determine if worksite cholesterol screening reaches only those who are already aware of their cholesterol and interested in lifestyle modification. Design. A voluntary worksite cholesterol screening was conducted followed by a survey of a random sample of nonparticipants. Setting. A large university worksite was the setting for this study. Subjects. Out of 9,137 university employees, 1,583 attended the voluntary screening, and a random sample of nonparticipants was obtained (n = 154), of which 87% (n = 138) responded. Measures. Subjects completed a questionnaire on health behaviors, perceived risk, self-efficacy for diet change, and attention to media messages. A capillary blood cholesterol level was also taken. Results. Nonparticipants were more likely to be male (64% versus 39%) and smokers (17% versus 9%), more likely to exercise, to have had a prior cholesterol measurement (64% versus 49%), and to “know” their cholesterol value (56% versus 26%). The two groups were otherwise similar. Over half (51%) of the participants were receiving their first cholesterol measurement. These subjects were younger, less educated, had less perceived risk, were less attentive to media messages, and more likely to be from a minority group than those individuals who had prior measurements. Discussion. These findings suggest that worksite cholesterol screening does not only reach those already aware of their cholesterols, but also can reach some persons not previously screened or concerned.

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Råstam, L., J. B. Admire, I. D. Frantz, W. Hellerstedt, D. M. Hunninghake, K. Kuba und R. V. Luepker. „Measurement of blood cholesterol with the Reflotron analyzer evaluated.“ Clinical Chemistry 34, Nr. 2 (01.02.1988): 426. http://dx.doi.org/10.1093/clinchem/34.2.426.

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Bowers, G. N. „Accuracy and blood cholesterol measurements.“ Clinical Chemistry 34, Nr. 1 (01.01.1988): 192. http://dx.doi.org/10.1093/clinchem/34.1.192.

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Sedor, F. A., C. M. Holleman, S. Heyden und K. A. Schneider. „Reflotron cholesterol measurement evaluated as a screening technique.“ Clinical Chemistry 34, Nr. 12 (01.12.1988): 2542–45. http://dx.doi.org/10.1093/clinchem/34.12.2542.

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Abstract We evaluated the analytical performance of Boehringer Mannheim Diagnostics' "Reflotron" analyzer for the measurement of cholesterol. Coefficients of variation (CVs) for whole-blood cholesterol were: within-day 2.0% and 2.2% at 1680 and 2670 mg/L, respectively; between-day 1.8% and 2.4% (n = 9 and 8). Results were similar for serum and heparinized or EDTA-treated single-donor plasma (CV 1.4% to 2.6%). CVs of results for two reconstituted commercial quality-control materials were 3.4% and 4.6%. Heparin and hematocrit were evaluated as interferents, and critical limits for interference were identified for bilirubin, hemoglobin, and triglyceride in blood and plasma or serum. When sample collection and analysis were controlled by trained personnel, results with the Reflotron (y) compared well with those by the Ektachem procedure (x) for both blood and serum samples: r = 0.950, y = 0.944x + 130 mg/L; and r = 0.955, y = 0.93x + 43.5 mg/L, respectively. The same comparability was observed when the analysis was performed by briefly trained high-school students: r = 0.980, y = 0.949x + 23 mg/L. Performance decreased when both collection and analysis were performed by laymen: r = 0.880, y = 0.870x + 186 mg/L.

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., Suwarsi. „Nursing Intervention in Decrease of Blood Cholesterol and Blood Pressure in The Lansia Group Provided Cupping Therapy in The Village of Wedomartani Sleman“. Pakistan Journal of Medical and Health Sciences 15, Nr. 5 (30.05.2021): 1305–8. http://dx.doi.org/10.53350/pjmhs2115513.5.

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Background: Much alternative therapy such as cupping therapy in the community as one of the cheap treatment efforts without side effects makes the challenge and the goal for nursing staff improve nursing services. The unfinished scientific verification of cupping therapy's alternative therapy makes nurses need to prove decreased blood pressure and cholesterol levels in the elderly. Objective: Scientific proof of cholesterol and blood pressure decrease after Cupping Therapy in an elderly group in Wedomartani Village, Sleman Yogyakarta Indonesia. Method: quantitative type with pseudo experimental research design. Pre-test and Post-test nonequivalent control group. The treatment group was given wet cupping therapy, while the control group was given dry cupping. Respondents were selected using a purposive sampling technique. Blood pressure measurement uses a digital tensimeter and cholesterol measurement using a digital blood cholesterol level measuring device. Results: The elderly blood cholesterol levels after the average therapy decreased 42.89 mg/dl, whereas blood cholesterol levels in the control group decreased an average of 20.95 mg/dl. The blood pressure of the elderly systole in the intervention group after the average therapy decreased 10.74 mmHg, whereas the control group's systole blood pressure decreased an average of 1.58 mmHg. Diastole blood pressure in the treatment group decreased 3,48 mmHg, in the diastole blood pressure control group increased 5,26 mmHg. Conclusions: Wet and dry cupping are both significantly associated with decreased blood cholesterol and blood pressure levels, but wet cupping lowers blood cholesterol levels by a mean difference of 21.95 mg/dl and mean systole blood pressure of 3.74 mmHg and pressure diastole blood difference of mean 9.1 mmHg. Keyword: Blood Pressure. Cupping Therapy, Cholesterol, Elderly

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warsi, Su. „Nursing Intervention in Decrease of Blood Cholesterol and Blood Pressure in The Lansia Group Provided Cupping Therapy in The Village of Wedomartani Sleman“. Pakistan Journal of Medical and Health Sciences 15, Nr. 5 (30.05.2021): 1305–8. http://dx.doi.org/10.53350/pjmhs211551305.

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Background: Much alternative therapy such as cupping therapy in the community as one of the cheap treatment efforts without side effects makes the challenge and the goal for nursing staff improve nursing services. The unfinished scientific verification of cupping therapy's alternative therapy makes nurses need to prove decreased blood pressure and cholesterol levels in the elderly. Objective: Scientific proof of cholesterol and blood pressure decrease after Cupping Therapy in an elderly group in Wedomartani Village, Sleman Yogyakarta Indonesia. Method: quantitative type with pseudo experimental research design. Pre-test and Post-test nonequivalent control group. The treatment group was given wet cupping therapy, while the control group was given dry cupping. Respondents were selected using a purposive sampling technique. Blood pressure measurement uses a digital tensimeter and cholesterol measurement using a digital blood cholesterol level measuring device. Results: The elderly blood cholesterol levels after the average therapy decreased 42.89 mg/dl, whereas blood cholesterol levels in the control group decreased an average of 20.95 mg/dl. The blood pressure of the elderly systole in the intervention group after the average therapy decreased 10.74 mmHg, whereas the control group's systole blood pressure decreased an average of 1.58 mmHg. Diastole blood pressure in the treatment group decreased 3,48 mmHg, in the diastole blood pressure control group increased 5,26 mmHg. Conclusions: Wet and dry cupping are both significantly associated with decreased blood cholesterol and blood pressure levels, but wet cupping lowers blood cholesterol levels by a mean difference of 21.95 mg/dl and mean systole blood pressure of 3.74 mmHg and pressure diastole blood difference of mean 9.1 mmHg. Keyword: Blood Pressure. Cupping Therapy, Cholesterol, Elderly

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Lasater, Thomas M., R. Craig Lefebvre, Annlouise R. Assaf, Ann L. Saritelli und Richard A. Carleton. „Rapid Measurement of Blood Cholesterol: Evaluation of A New Instrument“. American Journal of Preventive Medicine 3, Nr. 6 (November 1987): 311–16. http://dx.doi.org/10.1016/s0749-3797(18)31229-7.

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Stewart, Scott H., und Marc D. Silverstein. „Racial and ethnic disparity in blood pressure and cholesterol measurement“. Journal of General Internal Medicine 17, Nr. 6 (Juni 2002): 405–11. http://dx.doi.org/10.1046/j.1525-1497.2002.10524.x.

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A.Hassan, Hiba. „Measurement of some Biochemical Values in Hemodialysis Patients in Baghdad“. Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 23, Nr. 1 (28.03.2017): 14–18. http://dx.doi.org/10.31351/vol23iss1pp14-18.

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One hundred of dialysis patients' mean age ( 51.18Â±8.28) years and one hundred healthy control group , where carried out from different hospitals of Baghdad city , during the period between November /2012 until March/2013. Blood samples were collected before dialyzing for estimation the concentration of urea, creatinine, uric acid, random blood sugar , calcium and cholesterol by enzymatic method detected spectrophotometerically. The aim of this study is to determine concentration of urea, creatinine, uric acid, RBS , calcium and cholesterol in hemodialysis patients in Baghdad . The results showed that there were highly significant increases (P<0.01) in the mean of creatinine , urea , uric acid and RBS for patients (587.86Âµmol/l , 25.57 mmol/l, 414.36mmol/l and 6.47mmol/l) compared to the mean of healthy control (88.60 Âµmol/l , 5.07mmol/l ,270.76mmol/l and 4.65mmol/l ) was detected . Also there was highly significant decrease(P< 0.01) in the mean of calcium and cholesterol for patients (1.93mmol/l and3.33mmol/l) compared to the mean of healthy control (2.34mmol/l and5.02mmol/l). It is concluded that in hemodialysis was associated with the higher levels of urea ,creatinine , uric acid and RBS with low level of cholesterol and calcium. Key words: RBS (random blood sugar), SUA (serum uric acid), Cholesterol, Urea, Creatinine

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Simaremare, Eva Susanty, Septriyanto Dirgantara, Elsye Gunawan, Rani Dewi Pratiwi und Rusnaeni Rusnaeni. „Pemeriksaan Kesehatan Masyarakat Yapase, Distrik Depapre, Papua“. JPPM: JURNAL PENGABDIAN DAN PEMBERDAYAAN MASYARAKAT 1, Nr. 2 (14.12.2017): 123. http://dx.doi.org/10.30595/jppm.v1i2.1751.

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High blood pressure, diabetes mellitus (DM), uric acid, and cholesterol are disease that can kill patients. The purpose of ths study to support the government in health campaign efforts, especially in Yapase. This study was done by direct examination to participants and education them about health according to their examination result. Examination are blood pressure, glucose, uric acid, and cholesterol levels using GCU (Glocose / Cholesterol / Uric Acid)tTest. This study was held on Thursday 3 August 2017. The location was conducted in Yapase Hall. The number of participants were 32 people. The results show that 13 people (41%) had normal blood pressure, 10 people (31%) had prehypertension, and 9 people (28%) had hypertension. On blood glucose examination 6 people (19%) of the participants had low blood sugar and 26 people (81%) under normal circumstances. On the measurement of blood cholesterol, 2 people (6%) had hypercholesterolemia and 30 people (94%) had normal cholesterol levels under normal conditions. In the measurements of uric acid obtained 3 people (9%) had low uric acid levels, 11 people (34%) had normal uric acid levels and 18 people (56%) had high uric acid levels

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DHINAA, A. N., und P. K. PALANISAMY. „Z-SCAN TECHNIQUE FOR MEASUREMENT OF TOTAL CHOLESTEROL AND TRIGLYCERIDES IN BLOOD“. Journal of Innovative Optical Health Sciences 02, Nr. 03 (Juli 2009): 295–301. http://dx.doi.org/10.1142/s1793545809000565.

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The measurement of cholesterol and triglycerides in blood by Z-scan technique is proposed. The nonlinear refractive index of cholesterol and triglycerides was found to vary linearly with concentration. Hence by calculating the nonlinear refractive index it is possible to measure their concentration in the sample. These measured values are found in equivalence with conventional colorimetric method.

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Khan, Ayesha Rehan, Shruti Dorai und Yaseen Serry. „Optimising the measurement of blood glucose and cholesterol in patients who had an acute stroke: a quality improvement project“. BMJ Open Quality 10, Nr. 2 (Juni 2021): e001237. http://dx.doi.org/10.1136/bmjoq-2020-001237.

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Hypercholesterolaemia and diabetes are established modifiable risk factors for cerebrovascular disease. A baseline audit carried out on an acute stroke ward at a District General Hospital in East Kent showed variability in blood tests being requested on admission for patients who had a suspected stroke, in particular serum glucose and cholesterol levels. Our aim was to ensure that at least 80% of patients admitted to the stroke ward with a suspected stroke had blood glucose and cholesterol levels measured on admission, over an 18-week period.The percentage of patients admitted with a suspected stroke on the ward who had the appropriate investigations requested on admission was measured weekly. Quality improvement methodology was used to formulate three interventions in the form of Plan-Do-Study-Act cycles: (1) an educational email sent to doctors regarding the assessment of patients who had a stroke and admission blood tests required; (2) adaptation of the ‘Stroke Admission Clerking Proforma’ to include a list of bloods to be requested; (3) production of an all-inclusive ‘Stroke Bloods Panel’ on the online system for requesting bloods.At baseline, an average of 30% and 34% of patients had glucose and cholesterol levels requested on admission, respectively. These results increased to 43% and 40% after the first intervention; 71% and 61% after the second intervention; and after the final intervention, on average, 82% and 85% of patients had glucose and cholesterol levels requested, respectively. We therefore achieved our aim of ensuring that more than 80% of patients who had an acute stroke had the appropriate blood tests requested on admission.The modified stroke proforma and the blood panel were the most effective interventions. The changes were implemented in an additional hospital within the same Trust. We anticipate greater compliance with Royal College of Physicians (RCP), National Institute for Health & Care Excellence (NICE) and Trust guidelines regarding appropriate and timely prescription of antidiabetic and cholesterol-lowering medications for secondary preventative measures.

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McNamara, Judith R., G. Russell Warnick, Elizabeth Teng Leary, Ellison Wittels, Forrest E. Nelson, Mary F. Pearl und Ernst J. Schaefer. „Multicenter Evaluation of a Patient-Administered Test for Blood Cholesterol Measurement“. Preventive Medicine 25, Nr. 5 (September 1996): 583–92. http://dx.doi.org/10.1006/pmed.1996.0093.

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Umar, Usman, Syafruddin Syarif, Ingrid Nurtanio und Indrabayu. „A real time non-invasive cholesterol monitoring system“. MATEC Web of Conferences 331 (2020): 06005. http://dx.doi.org/10.1051/matecconf/202033106005.

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Hypercholesterolemia causes cardiovascular disease which is a disorder of the heart and blood vessels, one of the most significant causes of death in the world, and this needs to be anticipated by monitoring blood cholesterol levels regularly. The current method of monitoring blood cholesterol levels is using invasive technique by collecting blood samples. A simple device is needed to measure blood cholesterol levels that can be done without collecting blood samples. This study aims to develop a non- invasive technique for monitoring blood cholesterol levels using sensors utilizing infrared light absorption in body tissues, in order to simplify measuring blood cholesterol levels regularly for patients with hypercholesterolemia. The application of a non-invasive technique focused on developing a total blood cholesterol monitoring device using an infrared sensor with IR LED - 940nm wavelength as a transmitter. A photodiode was used as a detector with the wavelength range of 400-1100 nm and a microcontroller as the minimum system for controlling the value of the output voltage in the form of digital data and then converted onto total blood cholesterol. The measurement results using non-invasive technique was compared to the results using invasive technique.

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Elfira, Eqlima. „EFFECT OF PROGRESSIVE MUSCLE RELAXATION EXERCISE BASED ON ARDUINO UNO ON BLOOD SUGAR, CHOLESTEROL AND URID ACID LEVELS IN THE ELDERLY“. Nurse and Health: Jurnal Keperawatan 9, Nr. 2 (27.12.2020): 211–18. http://dx.doi.org/10.36720/nhjk.v9i2.193.

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Abstract Background:Objectives: This study aims to determine the effect of progressive muscle relaxation training on blood sugar, choleterol and uric acid levels in the elderly in Medan Sunggal sub-district.Methods: This study was an experimental study with one group by examining blood sugar, cholesterol and uric acid levels before and after progressive muscle relaxation training. The research respondents were 39 elderly people in environmental areas II and III of Medan Sunggal sub-district. Blood sugar, cholesterol and uric acid levels were measured before the first session and after the end of the progressive muscle relaxation training session three times a week for 4 weeks.Results: The results were analyzed by using the Wilcoxon test using spss 26. Blood sugar and cholesterol levels have the same measurement results, while the pre and post measurements of uric acid levels have an increase in value which means that there is an effect of progressive muscle relaxation training on uric acid levels with a p value <0.05. . which means that Ha is accepted means that there is a difference between pre and post progressive muscle relaxation training based on Arduino Uno.Conclusion:Progressive muscle relaxation training only affects uric acid levels and has no effect on cholesterol and blood sugar levels in the elderly.

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Liu, V. Y., T. Y. Lin, W. Schrier, M. Allen und P. Singh. „AccuMeter noninstrumented quantitative assay of high-density lipoprotein in whole blood“. Clinical Chemistry 39, Nr. 9 (01.09.1993): 1948–52. http://dx.doi.org/10.1093/clinchem/39.9.1948.

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Abstract A novel noninstrumented technology (ChemTrak AccuMeter) for the quantitative measurement of analytes in biological fluids was reported at the 1990 Oak Ridge Conference (Clin Chem 1990;36:1591-7). This instrument-free technology has been adapted for the quantitative measurement of high-density lipoprotein (HDL). An in situ lipoprotein separation method has been developed and incorporated into the test for HDL determination. The sensitivity of the assay system has been adjusted so that HDL is measured over a clinically significant range of 250 to 1000 mg/L. This compares to a range of 1000 to 4000 mg/L for the total cholesterol in the earlier reported assay. Like the AccuMeter total cholesterol test, the Accumeter HDL test system is self-contained and consolidates blood separation, lipoprotein separation, and specimen measurement into a single step. The test procedure is simple, and the results are accurate.

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Allen, M. P., A. DeLizza, U. Ramel, H. Jeong und P. Singh. „A noninstrumented quantitative test system and its application for determining cholesterol concentration in whole blood“. Clinical Chemistry 36, Nr. 9 (01.09.1990): 1591–97. http://dx.doi.org/10.1093/clinchem/36.9.1591.

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Abstract A novel noninstrumented technology has been developed for quantifying analytes of clinical interest in biological fluids. Application of this technology is exemplified by the development of a quantitative cholesterol test with performance equivalent to state-of-the-art instrumented methods. The assay chemistry combines two separate processes located in different areas of a test strip: enzymatic action on serum cholesterol to produce hydrogen peroxide (5 x 10 mm enzyme reagent pad) and quantification of the hydrogen peroxide (5 x 70 mm measurement region). Color bands are formed in the measurement area through the use of a redox-coupled indicator system. The height of the color band on the strip is directly proportional to the sample cholesterol concentration. A one-step cassette contains all components necessary to run the test and includes blood filtration and automatic sample measurement, so that unmeasured finger-stick whole-blood specimens can be analyzed by the non-technically trained user. The test is complete in less than 15 min, is read visually like a thermometer, and gives results that are in excellent correlation with established instrumented methods.

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Nurmawati, Thatit. „The Correlation of Weight and Blood Cholesterol Levels of White Rat (Rattus Norvegicus) with High-Fat Diet“. Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 3, Nr. 3 (01.12.2016): 202–6. http://dx.doi.org/10.26699/jnk.v3i3.art.p202-206.

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Cholesterol is an essential substance for the body. The role of cholesterol as material hormones,cell membranare needed by the body. This conditionchanges into a distrubtion if the cholesterollevels in the blood increase. Weight becomes one of this trigger. The consumption of high-fat foodsincrease weight which resulting in the increase of cholesterol cases. The purpose of this study was todetermine the level of correlations between weight and cholesterol levels after being given a high-fatdiet.The study used rats (Rattus norvegicus) sex male, 16 rats with age between 1-2 months. Rats weightrange between 100-150 gr and in healthy conditions. The giving of high-fat diet were in the form ofchicken feed, duck eggs, goat oil, lard and flour for 8 weeks. The data measurement done by scales andmeasuringcholesterol levels through the end of the tail by means of easy touch. The data analysis weredone to understand level of correlation between variables. The presentation of the data used tables. Theresults showed body weight of rats did not change after administration of a high-fat diet. The cholesterolslevels of the subjects were high. Theadministration of high-fat diet from egg yolk dan goat oilcouldincrease the level of cholesterol. There was a correlation between weight and cholesterol levels afterbeing given a high-fat diet (p <0.5). It was needed to repeatthe measurements to determine changes incholesterol levels and other factors that affect thigh blood to cholesterol levels.

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Simanullang, Komandaniel, und Joseph Partogi Sibarani. „Pengaruh Pemberian Alpukat terhadap Kadar Kolesterol LDL Darah pada Mahasiswa/i Obesitas di Fakultas Kedokteran Universitas HKBP Nommensen Medan“. Nommensen Journal of Medicine 6, Nr. 1 (02.11.2020): 13–16. http://dx.doi.org/10.36655/njm.v6i1.237.

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Background: Low Density Lipoprotein (LDL) is a lipoprotein that contains more cholesterol. High levels of blood LDL cholesterol are associated with obesity and increased of risk factor of cardiovascular disease. Avocado (Persea americana) is a well known and popular fruit in society. The active ingredient (omega 9-oleic acid) of avocados can be use to decrease LDL cholesterol levels and increase HDL (High Density Lipoprotein) cholesterol levels in blood in order to reduce the risk factor of cardiovascular disease. Objective: This study aims to determine the effect of avocado consumption on blood LDL cholesterol levels in obese students in Medical Faculty of Universitas HKBP Nommensen. Method: This study used a pre-experimental design one group pretest and posttest study. Subjects were 20 obese students of Medical Faculty of Universitas HKBP Nommensen and selected by simple random sampling technique. For the first 14 days, samples are given dietary intervention and the next 14 days given dietary intervention and avocado juice. Measurement of LDL cholesterol levels was done before and after 14 days given avocado juice. Data analysis used paired T test to analyze differences in blood LDL cholesterol levels before and after being given avocado juice. Results: The results are average value of blood LDL cholesterol levels on pretest was 137.1 mg / dL and posttest was 128.25 mg / dL with mean reduction was 8.85 mg / dL. Paired T test analysis shows that the avocados effect to blood LDL cholesterol is significantly influenced with value of p = 0.036 (p <0.05). Conclusion: There is an effect of avocado consumption on blood LDL cholesterol levels.

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Sterling, B., T. Kiang, K. Subramanian, M. Saltman, W. Smart, M. Tsay, J. Sugarman, D. Patel, D. Monger und D. Martin. „Simultaneous Patient-Side Measurement of Hemoglobin, Glucose, and Cholesterol in Finger-Stick Blood“. Clinical Chemistry 38, Nr. 9 (01.09.1992): 1658–64. http://dx.doi.org/10.1093/clinchem/38.9.1658.

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Abstract We describe a multianalyte assay system for patient-side use comprising single-use plastic cartridges and a small monitor. Hemoglobin, glucose, and cholesterol can be simultaneously measured in 3 min in an unmeasured volume of blood. The sample is drawn by capillary action into four channels for delivery to assay-specific stacks containing a set of closely apposed layers. The distal layer is a membrane that acts as the optical surface for reflectance optics. For glucose and cholesterol assays, erythrocytes are removed by a fibrous filter layer and oxidase-peroxidase chemical reactions contained in the optical membrane generate a colored product. For hemoglobin measurement, blood is lysed by detergent contained in a porous disk. The amount of color reaching the optical membrane is measured by fiber optics. To ensure fail-safe operation, sensors verify sample sufficiency and degree of hemolysis. The assays perform comparably with laboratory methods.

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Hopkins, K. D., E. D. Lehmann, R. G. Gosling, J. R. Parker und P. H. Sönksen. „Biochemical Correlates of Aortic Distensibility in vivo in Normal Subjects“. Clinical Science 84, Nr. 6 (01.06.1993): 593–97. http://dx.doi.org/10.1042/cs0840593.

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1. Non-invasive aortic compliance measurements have been used previously to assess the distensibility of the aorta in several pathological conditions associated with increased cardiovascular risk. In adult patients with familial hypercholesterolaemia and those with growth hormone deficiency, aortic compliance has been found to correlate inversely with plasma cholesterol levels and age. We set out to establish if a relationship existed between the biophysical measurement of aortic compliance and biochemical variables in normal healthy adult subjects. 2. Blood pressure-corrected aortic distensibility, fasting insulin, insulin-like growth factor-I, total cholesterol, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol and triacylgiycerol were measured in 38 (18 males, 20 females) normotensive healthy adults. 3. Blood pressure-corrected aortic distensibility was found to correlate inversely with age (r = −0.67, P <0.001), low-density lipoprotein-cholesterol (r = −0.37, P <0.02) and the low-density lipoprotein-/high density lipoprotein-cholesterol ratio (r = −0.33, P <0.05) and positively with insulin-like growth factor-I (r = 0.47, P <0.01). On separate analysis by sex, significant inverse correlations were observed in females between aortic distensbility and total cholesterol (r = −0.50, P <0.02), low-density lipoprotein-cholesterol (r = −0.55, P <0.01) and age (r = −0.74, P <0.001). A positive correlation was found between aortic distensibility and insulin-like growth factor-I (r = 0.48, P <0.05). On forced stepwise regression analysis, however, only age (P <0.02) was found to be significant. In males, an inverse correlation was found between aortic distensibility and age (r = −0.57, P <0.01), low-density lipoprotein-cholesterol (r = −0.51, P <0.05) and the low-density lipoprotein-/high-density lipoprotein-cholesterol ratio (r = −0.63, P <0.01). Positive correlations were observed between aortic distensibility and high-density lipoprotein-cholesterol (r = 0.48, P <0.05) and insulinlike growth factor-I (r = 0.48, P <0.05). On forced stepwise regression analysis the low-density lipoprotein-/high-density lipoprotein-cholesterol ratio (P <0.02) and age (P <0.04) were found to be the only significant independent predictors of aortic distensibility in males. 4. In normal adult subjects insulin-like growth factor-I and high-density lipoprotein-cholesterol are associated with increased aortic distensibility, whereas low-density lipoprotein-cholesterol is associated with aortic stiffening. We suggest that the measurement of blood pressure-corrected aortic distensibility in normal, healthy subjects may potentially be a useful, non-invasive research tool for investigating the effect of biochemical factors on the biophysical properties of the aortic wall.

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Choudhury, N., P. M. Wall und A. S. Truswell. „Effect of time between measurements on within-subject variability for total cholesterol and high-density lipoprotein cholesterol in women“. Clinical Chemistry 40, Nr. 5 (01.05.1994): 710–15. http://dx.doi.org/10.1093/clinchem/40.5.710.

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Abstract A single blood cholesterol measurement may not accurately reflect an individual's true mean concentration. If duplicate blood samples are taken, what number of days between sampling gives the best chance of detecting the maximum within-subject variation? In this study, we analyzed 20 serial blood samples obtained from each of 13 healthy, menstruating women over 35 days. Variability was calculated as the semivariogram, which gives the average squared difference between replicate samples taken over a range of sampling intervals. Data were available for a complete set of intervals from 1 to 26 days. Variability in total cholesterol (TC) increased as the interval between sampling increased from 1 to 12 days. With high-density lipoprotein cholesterol (HDL-C), variability increased from 1- to 7-day intervals. In practice, our results suggest that, irrespective of the time of menstruation, the minimal interval for collecting a second blood sample for TC and HDL-C assays is approximately 2 weeks.

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Patel, Nishith, Bernard F. Rocks und S. Andrew Iversen. „Direct Measurement of Low Density Lipoprotein in Whole Blood by Silver-Enhanced Gold-Labelled Immunoassay“. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 29, Nr. 3 (Mai 1992): 283–86. http://dx.doi.org/10.1177/000456329202900305.

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A competitive silver-enhanced gold-labelled immunoassay has been developed for the direct measurement of low density lipoprotein (LDL) in whole blood. Immobilized LDL and sample LDL compete for added antibody. Quantitation of the bound antibody/antigen complex is achieved by the addition of gold-labelled antiimmunoglobulin G followed by enhancement of absorbance by addition of silver ions. Whole-blood samples from fasting patients were assayed directly for LDL by the procedure and the corresponding plasma samples were assayed for total cholesterol, high density lipoprotein and triglycerides followed by the indirect calculation of LDL cholesterol. The correlation between the two methods was good (r = 0·82) and the SEGLISA exhibited good precision.

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Safdar Ali Shaikh, Afsheen Illahi Shaikh und Dr. Lubna Naz. „Effective role of olive oil use on lipid profile, blood pressure and blood glucose in subjects of metabolic syndrome“. BioSight 3, Nr. 1 (30.06.2022): 11–15. http://dx.doi.org/10.46568/bios.v3i1.65.

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Study was taken with an object to investigate the role of oil extracted from olives on lipid profile, blood pressure and glucose level in subjects having metabolic syndrome. A total of 115 subjects of metabolic syndrome according to International Diabetes Federation criteria, aged between 20-40 years were included. Lipid profile, blood pressure and fasting glucose levels were performed at base line. 30ml of olive oil per day in divided doses 15 ml in the morning and 15 ml in the evening was given to these subjects for six weeks. Then lipid profile, blood pressure and fasting glucose level were performed and compared with base line values. Significant decrease was observed in total cholesterol, low density lipoprotein cholesterol, triglycerides and increase in high density lipoprotein cholesterol, all P values < 0.01. Nonsignificant low level of fasting blood sugar was observed. Significant decrease in systolic and diastolic blood pressure at P value < 0.01 was observed. It is concluded that use of olive oil caused improvement in lipid profile and blood pressure measurement in metabolic syndrome subjects significantly while nonsignificant decrease was observed in fasting blood glucose.

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Supriami, Kelvin, Ira Puspitawati, Dyah Samti Mayasari und Anggoro Budi Hartopo. „Increased Platelet-derived Microparticles Counts is Correlated with Elevated Blood LDL Cholesterol in Acute Myocardial Infarction“. Indonesian Biomedical Journal 14, Nr. 3 (08.09.2022): 261–8. http://dx.doi.org/10.18585/inabj.v14i3.1892.

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BACKGROUND: Platelet-derived microparticles (PDMPs) and low-density lipoprotein (LDL) cholesterol are contributing factors to acute myocardial infarction (AMI). However, the association between LDL cholesterol and PDMPs in AMI has not fully discovered. This study assessed the correlation between these two parameters in patients diagnosed with AMI.METHODS: This was an observational cross-sectional study involving 95 subjects with AMI. The blood measurement of PDMPs counts and LDL cholesterol levels were conducted concomitantly within 24 hours of admission. PDMPs count was analyzed by flow-cytometry method, meanwhile the LDL cholesterol was measured with enzymatic and colorimetric methods. For further analysis, subjects were further divided into LDL cholesterol level ≥130 mg/dL and <130 mg/dL. A statistical test was conducted for a correlative and comparative analyses.RESULTS: A correlative analysis to assess the association between PDMPs counts and LDL cholesterol level depicted a low but significant positive correlation (r=0.231, p=0.024). Furthermore, mean PDMPs counts was significantly higher in subjects with LDL cholesterol level ≥130 mg/dL compared to LDL cholesterol level <130 mg/dL (12,499.59 (95% CI: 8,507.44-16,491.74) counts/μL vs. 9,267.23 (95% CI: 4,445.45-14,089.01) counts/μL; p=0.039).CONCLUSION: There was a significant correlation between PDMPs counts and LDL cholesterol levels in AMI. A significantly increased PDMPs counts were found in subjects with LDL cholesterol level ≥130 mg/dL. Therefore, it is recommended to measure PDMPs in patients with high LDL cholesterol levels as both might be significant AMI biomarkers.KEYWORDS: acute myocardial infarction, LDL-cholesterol, platelet microparticles, platelet activation

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Mahapatra, Dr Nancy Namrata, und Dr Tarachand Kadtuji Kamble. „Myocardial Performance Index In Prediabetes In Medical Staff“. International Journal of Medical Science and Clinical invention 6, Nr. 07 (09.07.2019): 4513–17. http://dx.doi.org/10.18535/ijmsci/v6i7.01.

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Background: To study myocardial performance index in prediabetes in medical staff. To correlate MPI with cardiovascular risk factors. Methods: After subject selection, informed consent was taken from the cases and controls. Detailed history was taken and physical examination was done which included weight, height, body mass index (BMI), waist circumference, hip circumference, waist-hip ratio (WHR) and blood pressure measurement. After physical examination, biochemistry measurements including fasting blood sugar (FBS), post-meal blood sugar (PMBS), serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) were done. Myocardial performance index (MPI) was calculated by 2D-ECHO. Results: BMI, male WHR, serum cholesterol, TG, LDL and MPI was significantly higher in cases (prediabetics) as compared to controls while serum HDL was lower in cases as compared to controls, which was non-significant. Out of 50 prediabetics, 32 (64%) had abnormal MPI with p=0.0001. There was no correlation of MPI with cardiovascular risk factors like BMI, WHR and fasting lipid profile. Conclusion: BMI, male WHR, serum cholesterol, TG, LDL and MPI was significantly higher in cases as compared to controls. However, there was no significant correlation between MPI and other cardiovascular risk factors.

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Bachorik, P. S., R. H. Bradford, T. Cole, I. Frantz, A. M. Gotto, K. Roberts, G. R. Warnick und O. D. Williams. „Accuracy and precision of analyses for total cholesterol as measured with the Reflotron cholesterol method.“ Clinical Chemistry 35, Nr. 8 (01.08.1989): 1734–39. http://dx.doi.org/10.1093/clinchem/35.8.1734.

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Abstract We compared plasma cholesterol measurements made with the Boehringer Mannheim Reflotron reflectance photometric analyzer in 1298 capillary blood samples with measurements made in venous blood samples collected at the same time and analyzed in four standardized Lipid Research Clinics laboratories. The Reflotron measurements averaged 0.8% to 7.8% lower than the laboratory values. Correlations (r) between the two sets of measurements ranged from 0.92 to 0.96. In some samples, however, the Reflotron values differed from the laboratory values by greater than or equal to 12%; the cholesterol concentrations in these samples tended to be higher than in those for which better agreement was observed. The smaller negative biases were observed when test strips were used that were calibrated with reference to the Centers for Disease Control Reference Method for cholesterol. The agreement between sequential Reflotron values averaged less than or equal to 4.3%. There was an average difference of less than or equal to 1.0% between Reflotron measurements made in each of two sequential capillary blood samples taken from a single finger puncture.

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Park, Yoonjin, und Jungjin Han. „Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey“. International Journal of Environmental Research and Public Health 18, Nr. 19 (30.09.2021): 10315. http://dx.doi.org/10.3390/ijerph181910315.

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(1) Objective: Lead, a heavy metal that exists commonly in air, soil and crops may cause chronic disease in the cardiovascular system. The purpose of this study is to investigate how blood lead levels affect cardiovascular disease in adults. (2) Study Design and Participants: It is a cross-sectional, descriptive study using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data from a total of 1929 participants, derived from the KNHANES, conducted by the Korea Centers for Disease Control and Prevention, in 2017, were analyzed using SPSS version 25.0. (3) Measurement: The cardiovascular disease risk was calculated using the Framingham risk score. There was a strong positive correlation between blood lead levels and the Framingham risk score. Furthermore, of the FRS sub-criteria, systolic blood pressure, HDL cholesterol level and total cholesterol level all also showed a significant correlation. (4) Results: We analyzed the correlation between PbB levels and the FRS sub-criteria, including systolic blood pressure, HDL cholesterol level, total cholesterol level and the FRS total. We found a significant positive correlation between PbB levels and systolic blood pressure, FRS total and total cholesterol level (p < 0.05), as well as a significant negative correlation with HDL cholesterol level (p < 0.05). (5) Conclusion: Based on the perception that there is no lower toxicological threshold for blood lead, it is necessary to restrict lead in product manufacturing for the purpose of public health. In addition, it is necessary to be aware of the dangers of exposure to even small amounts of lead in daily life.

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Fahlevi, Zoerul, Al Azhar, Arman Sayuti, M. Isa, Mulyadi Adam und Herrialfian Herrialfian. „11. Blood Chemistry of Local Swamp Buffaloes (Bubalus bubalis) of Aceh“. Jurnal Medika Veterinaria 11, Nr. 1 (05.10.2017): 66–70. http://dx.doi.org/10.21157/j.med.vet..v11i1.4337.

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This study was done to determine blood chemistry of local swamp buffaloes in Aceh. Blood samples were collected from 15 local buffaloes slaughtered at the abattoir of Banda Aceh and 16 local buffaloes slaughtered at the abattoir of Aceh Besar using EDTA as an anticoagulant. Measurement of uric acid, cholesterol and glucose levels was done using Easy Touch rapid test whereas hemoglobin concentration was determined using Sahli method. Data obtained was analyzed by t-test using GraphPad Prims 6 software. The results showed that concentration of uric acid, cholesterol, glucose and hemoglobin in the blood of local swamp buffaloes were 13.80±3.62 mg/dl, 139.50±39.71 mg/dl, 81.81±21.34 mg/dl, and 10.86±2.78 g/dl, respectively. In the male local buffaloes, the level of uric acid, cholesterol, glucose and Hb were 12.23±3.94 mg/dl, 126.10±33.99 mg/dl, 73.58±22.54 mg/dl, and Hb 11.20±3.86 g/dl, respectively. For female local buffaloes, uric acid level was 14.59±3.29 mg/dl, cholesterol was 147.70±41.61 mg/dl, glucose was 87.00±19.35 mg/dl, and Hb was 10.64±1.91 g/dl. Statistical analysis indicated that there was no difference in the chemistry profiles in the blood of local swamp buffaloes of Aceh according to sex.

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Ila Fadila. „FORMULASI MODEL KADAR KOLESTEROL SERUM MELALUI PENDEKATAN UKURAN SKINFOLD PADA ORANG DEWASA“. Jurnal Matematika Sains dan Teknologi 7, Nr. 1 (15.08.2006): 58–70. http://dx.doi.org/10.33830/jmst.v7i1.629.2006.

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The study was conducted to explore the relationship between anthropometric measurement, i.e. skinfold thickness and cholesterol consentration in adult male and female blood. Other variables assumed as confounders including respondent characters namely: age, sex, ethnic, smoking habit, and activity. Analysis was done to a data from Health and Nutrition Survey on Adult on six cities in Indonesia. Prediction model of serum cholesterol with nutritional status assessment was developed by multiple regression analysis. Backward elimination procedure was used for model processing. The study result indicated that there was positive correlation between cholesterol and skinfold, age, and ethnic. Prediction model of serum cholesterol can be showed: Serum Cholesterol = 153,58 + 0,36 Skinfold + 0,34 age – 1,46 Sex – 48,71 Activity + 27,84 Ethnic

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Heilbraun, Jeff, Anastasia M. Snelling und Marc A. Schaeffer. „Comparison of Total Cholesterol Measurement Using Reflotron Capillary Analysis and Laboratory Venous Blood Analysis“. American Journal of Health Promotion 10, Nr. 1 (September 1995): 12–14. http://dx.doi.org/10.4278/0890-1171-10.1.12.

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Myers, Gary L., Mary M. Kimberly, Parvin P. Waymack, S. Jay Smith, Gerald R. Cooper und Eric J. Sampson. „A Reference Method Laboratory Network for Cholesterol: A Model for Standardization and Improvement of Clinical Laboratory Measurements“. Clinical Chemistry 46, Nr. 11 (01.11.2000): 1762–72. http://dx.doi.org/10.1093/clinchem/46.11.1762.

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Abstract Background: Accurate and precise measurement of blood cholesterol plays a central role in the National Cholesterol Education Program’s strategy to reduce the morbidity and mortality attributable to coronary heart disease. Matrix effects hamper the ability of manufacturers to adequately calibrate and validate traceability to the National Reference System for Cholesterol (NRS/CHOL). CDC created the Cholesterol Reference Method Laboratory Network (CRMLN) to improve cholesterol measurement by assisting manufacturers of in vitro diagnostic products with validation of the traceability of their assays to the NRS/CHOL. Methods: CRMLN laboratories established the CDC cholesterol reference method (modification of the Abell-Levy-Brodie-Kendall chemical method) and are standardized using CDC frozen serum reference materials. CRMLN laboratories use common quality-control materials and participate in monthly external performance evaluations conducted by CDC. The CRMLN performance criteria require member laboratories to agree with CDC within ± 1.0% and maintain a CV ≤2.0%. Results: From 1995 to 2000, the CRMLN laboratories met the accuracy criterion 97% of the time and the precision criterion 99% of the time. During this time period, the CRMLN maintained an average bias to CDC of 0.01% and an average collective CV of 0.33%. Conclusions: CDC established the CRMLN as the first international reference method laboratory network. The CRMLN assists manufacturers in the validation of the calibration of their diagnostic products so that clinical laboratories can measure blood cholesterol more reliably. The CRMLN can serve as a model for other clinical analytes where traceability to a hierarchy of methods is needed and matrix effects of the field methods with processed calibrators or reference materials are present.

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Fatimah, Siti, und Yuliana Prasetyaningsih. „Pengaruh Pemberian Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea Batatas (L.) Lam) terhadap Kadar Kolesterol Ldl Tikus Hiperkolesterolemia“. Jurnal Nasional Teknologi Terapan (JNTT) 2, Nr. 2 (26.01.2019): 184. http://dx.doi.org/10.22146/jntt.42772.

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Hypercholesterolemia is still a health problem today because it is associated with the onset of cardiovascular disorders with various complications. High cholesterol levels carried by the blood will accumulate in the arteries that cause atherosclerosis. Blood clots and blockage of blood vessels can result in the stroke or heart attack. Flavonoids that are found in purple sweet potato leaves are quercetin. Quercetin has antioxidant effects that can improve blood vessel endothelial function, reduce LDL sensitivity to free radical effects, and reduce blood lipid levels. This study aims to determine the effect of ethanol extract of purple sweet potato leaves on LDL cholesterol level of hypercholesterolemia rat. The experiment was conducted experimentally using 2 groups of Wistar rats (each group consisting of 5 tails), namely the control group and the treatment group. Induction of hypercholesterolemia was performed with a high-fat diet for 7 days. The purple sweet potato ethanol extract was administered sonde in the treatment group with a quercetin dose of 2 mg /kg/day for 14 days and the measurement of LDL cholesterol was performed on days 10 and 24 by the CHOD-PAP method. Data were analyzed by Paired t-test. The results showed that LDL cholesterol level in the treatment group showed that 5 mice had decreased, the mean decrease of 32,49 mg/dl while control group 3 decreasing, mean 0,65 mg /dl. There was a significant difference (p <0.05) on changes in LDL cholesterol levels in the treatment group. Provision of purple sweet potato ethanol extract with quercetin dose of 2 mg/kg for 14 days can decrease LDL cholesterol level of hypercholesterolemia rat. From the results of this study is expected to optimize the utilization of purple sweet potato leaves (Ipomoea batatas (L.) Lam) as a drug for lowering LDL cholesterol.

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Bezek, Štefan, Zuzana Brnoliaková, Ružena Sotníková, Vladimír Knezl, Ema Paulovičová, Jana Navarová und Viktor Bauer. „Monotherapy of experimental metabolic syndrome: I. Efficacy and safety“. Interdisciplinary Toxicology 10, Nr. 3 (01.11.2017): 81–85. http://dx.doi.org/10.1515/intox-2017-0013.

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AbstractElevated plasma cholesterol, especially low density lipoprotein (LDL) cholesterol, is one of the major risk factors for atherosclerosis and coronary heart disease. Hereditary hypertriglyceridemic rats (hHTG) were developed as a new inbred model for the study of relationships between blood pressure and metabolic abnormalities. The aim of this work was to determine the cholesterol-lowering and antioxidant effects of the novel pyridoindol derivative SMe1EC2, compared to the cholesterol-lowering drug atorvastatin, in rats fed either standard or high-fat and high-cholesterol diet (HFC; 1% cholesterol and 7.5% lard fat). Male hHTG rats fed HFC (HTG+HFC) were administered with SMe1EC2 or atorvastatin (both 50 mg/kg/day p.o.) for 4 weeks. Physiological status of animals was monitored by the measurement of preprandial glucose levels and blood pressure. Lipid profile was characterized by the serum levels of total cholesterol (TC), HDL-, LDL-cholesterol and triglycerides (TRG). The concentration of thiobarbituric acid reactive substances (TBARS) was evaluated in the kidney, liver and serum. Further, the assessment of pro-inflammatory cytokines TNF-α, IL-1 and IL-6 in the serum was completed. Feeding the animals with HFC diet resulted in increased serum levels of TC, LDL and TRG. SMe1EC2 ameliorated serum levels of LDL in hHTG rats, both on standard and HFC diet. These effects were comparable with those of the standard hypolipidemicum atorvastatin. SMe1EC2 lowered blood pressure, tissue TBARS concentrations and serum IL-1 levels of HTG+HFC rats. Beneficial effects together with very good toxicity profile predestinate SMe1EC2 to be promising agent for further surveys related to metabolic syndrome features.

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Schectman, G., M. Patsches und E. A. Sasse. „Variability in cholesterol measurements: comparison of calculated and direct LDL cholesterol determinations“. Clinical Chemistry 42, Nr. 5 (01.05.1996): 732–37. http://dx.doi.org/10.1093/clinchem/42.5.732.

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Abstract Calculated low-density lipoprotein cholesterol (LDL-C) concentrations determined from the Friedewald equation have a large intraindividual CV, in part because the calculation incorporates the variability of cholesterol, high-density lipoprotein cholesterol (HDL-C), and triglyceride measurements. We studied whether a new assay that measures LDL-C directly will reduce this variability and reduce the need for averaging serial specimens. Four blood samples were obtained 1 week apart from 35 mildly hypercholesterolemic subjects and analyzed for total cholesterol, triglycerides, and HDL-C. LDL-C was calculated by the Friedewald equation, and was also measured directly with a commercially available direct LDL-C assay. The intraindividual CV for the direct and calculated LDL-C assays were similar [CV of direct LDL-C assay (mean +/- SE): 6.8 +/- 0.5% vs calculated LDL-C: 7.3 +/- 0.6%; difference 0.44%, 95% confidence interval: -0.7-1.5%]. For both assays, at least two blood tests were required from each subject to reduce total variability of LDL-C to less than or equal to 5%. We conclude that the direct LDL-C assay did not reduce the variability in LDL-C compared with the conventional LDL-C calculation. However, it may have a specific role in lipid disorder evaluation and (or) monitoring when triglycerides are increased or the LDL-C value alone is needed.

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Chen, Neng, Xianghou Xia, Liqiang Qin, Li Luo, Shufen Han, Guiping Wang, Ru Zhang und Zhongxiao Wan. „Effects of 8-Week Hatha Yoga Training on Metabolic and Inflammatory Markers in Healthy, Female Chinese Subjects: A Randomized Clinical Trial“. BioMed Research International 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/5387258.

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We aimed to determine the effects of an 8 wk Hatha yoga training on blood glucose, insulin, lipid profiles, endothelial microparticles (EMPs), and inflammatory status in healthy, lean, and female Chinese subjects. A total of 30 healthy, female Chinese subjects were recruited and randomized into control or yoga practice group. The yoga practice included 8 wks of yoga practice (2 times/wk) for a total of 16 times. Fasting blood samples were collected before and after yoga training. Plasma was isolated for the measurement of lipid profiles, glucose, insulin, EMPs, and inflammatory cytokines. Whole blood was culturedex vivoand stimulated with lipopolysaccharide (LPS) and Pam3Cys-SK4. Peripheral blood mononuclear cells (PBMCs) were isolated for the measurement of TLR2 and TLR4 protein expression. Yoga practice significantly reduced plasma cholesterol, LDL-cholesterol, insulin levels, and CD31+/CD42b− EMPs. Cultured whole blood from the yoga group has reduced proinflammatory cytokines secretion both at unstimulated condition and when stimulated with Pam3Cys-SK4; this might be associated with reduced TLR2 protein expression in PBMCs after yoga training. Hatha yoga practice in healthy Chinese female subjects could improve hallmarks related to MetS; thus it can be considered as an ancillary intervention in the primary MetS prevention for the healthy population. This trial is registered withChiCTR-IOR-14005747.

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Widyamurti, Pratiwi, Rusdi Rusdi und Sri Rahayu. „PERBANDINGAN PROFIL LIPID PADA SERUM DARAH PENDERITA HIPERTENSI DAN NORMOTENSI“. BIOMA 11, Nr. 2 (09.10.2015): 131. http://dx.doi.org/10.21009/bioma11(2).3.

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ABSTRACT Increased blood pressure more than 140/90 mmHg taken from three measurement in 24 hours can be diagnosed as hypertension. Abnormality of lipid values condition was found at many hypertensive. Based on this reason examination of lipid profile in hypertensive and normotensive should be done. The aim of this research was to measure and compare lipid profile on blood serum in hypertensive and normotensive. Lipid profile was measured by Konelab 20XT clinical chemistry analyzer. Ex Post Facto used as method and Cross-sectional used as design. A total of 50 blood samples collected from Hypertensive (N1=25) and normotensive (N2=25) from June to August 2014. SPSS 16.0 was used to analyze the data, T-test was used to compare value of LDL cholesterol, HDL cholesterol and total cholesterol while U Mann-Whitney test was used to compare value of triglyceride. The result of this research showed that the mean value of triglyceride was 146.56 mg/dL in hypertensive and 143.92 mg/dL in normotensive (p=0.11). The mean value of LDL cholesterol was 129.80 mg/dL in hypertensive and 136.72 mg/dL in normotensive (p=0.62). The mean value of HDL cholesterol was 38.80 mg/dL in hypertensive and 45.04 mg/dL in normotensive (p=0.1). The mean value of total cholesterol was 201.04 mg/dL in hypertensive and 221.88 mg/dL in normotensive (p=0.25). In conclusion, there was no different of lipid profile on blood serum in hypertensive and normotensive. Keywords: hypertension, lipid profile, normotensive

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Sarastri, Yuke, Abdul Halim Raynaldo, Kamal Kharrazi Ilyas und Dian Anindita Lubis. „Cardiometabolic Profile Screening as an Early Detection of Cardiometabolic Risk“. Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) 4, Nr. 2 (09.08.2022): 70–76. http://dx.doi.org/10.32734/jetromi.v4i2.9156.

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Background: Cardiometabolic risk profile is a set of interconnected risk factors, namely abdominal obesity, hypertension, dyslipidemia, hyperglycemia, and hyperinsulinemia, and causes global death. This study was conducted to obtain data on cardiometabolic profiles of people who participated in the Commemoration of World Hypertension Day 2021 at RSUP H Adam Malik Medan Method: This research is a descriptive study with a cross-sectional research design peoples namely by looking at the description of the cardiometabolic profile. The sample is an affordable population that meets the inclusion criteria, people with age >18 years old. Variables of blood pressure, waist circumference, blood sugar levels, and total cholesterol levels are numerical variables. Blood pressure examination is measured using a sphygmomanometer and expressed in mmHg units. The measurement of the abdominal circumference is carried out by examining the size of the abdominal circumference obtained using a tape measure in cm. Blood sugar levels are obtained from the results of measuring blood sugar levels during laboratory examination of blood in mg/dl units. Cholesterol levels are obtained from the results of measuring total cholesterol levels from blood laboratory examinations in mg/dl. Results: All subjects in this study (n= 100) are 42 men and 58 women with normal waist circumference, and education level strata -1, only 9% of the subjects had high blood sugar levels, and 41% of subjects were classified as central obesity 9% of subjects. Most patients (91%) with normal postprandial glucose and high total cholesterol 66%. Conclusion: In this study, most of the cardiometabolic risks of patients are overweight/obesity and dyslipidemia

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MARSALINA, MEISA, SAMIGUN SAMIGUN und ENDANG SRI HARDJANTI. „The influence of aqueous extract of roselle (Hibiscus sabdariffa) calyx on blood cholesterol level and body weight in rats“. Biofarmasi Journal of Natural Product Biochemistry 9, Nr. 2 (17.08.2011): 43–49. http://dx.doi.org/10.13057/biofar/f090203.

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Marsalina M, Samigun, Hardjanti ES. 2011. The influence of aqueous extract of roselle (Hibiscus sabdariffa) calyx on blood cholesterol level and body weight in rats. Biofarmasi 9: 43-49. This study aimed to investigate the influence of aqueous extract of roselle calyx on blood cholesterol level and body weight in rats. This experimental research was arranged as a pre and post-test controlled group design. Thirty Sprague-Dawley rats, with 3 months of age and 250 g in average weight, were used as an animal model. Those rats were grouped equally into five groups, i.e. negative control (aquadest), positive control (0.26 mg lovastatin/200 g body weight of rats/2 mL), the first dose of aqueous extract of roselle calyx (65 mg/200 g/2 mL), the second dose of aqueous extract of roselle calyx (130 mg/200 g/2 mL), and the third dose of aqueous extract of roselle calyx (195 mg/200 g/2 mL). The measurement of rat blood cholesterol level was conducted before and after treatment, while the rat body weight was measured once a week. The result of this study was analyzed by using one-way ANOVA statistical test. The one-way ANOVA statistical test showed no significant difference on reducing blood cholesterol level with p=0.327 (p>0.05) and body weight in rat with p=0.154, p=0.214, and p=0.938 (p>0.05). This study concluded that the aqueous extract of roselle calyx has no influence on lowering blood cholesterol level and body weight in rats.

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Kadariswantiningsih, Ika Nindya, Mochammad Thaha, Cahyo Wibisono Nugroho, Berliana Hamidah, Haerani Rasyid, Zaky El Hakim, Maulana Muhtadin Suryansyah et al. „Could Complete Blood Count Parameters and Non-fasting Cholesterol Profile Describe Inflammation and Oxidative Stress in Chronic Kidney Disease?“ Indonesian Biomedical Journal 10, Nr. 3 (28.12.2018): 270–7. http://dx.doi.org/10.18585/inabj.v10i3.451.

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BACKGROUND: Establishment of inexpensive clinical laboratory tests to evaluate inflammation and oxidative stress is urgently needed in the limited resources settings. This study aims to investigate the potential of complete blood count (CBC) parameters and non-fasting cholesterol profile parameters to describe inflammation and oxidative stress in chronic kidney disease (CKD) patients.METHODS: Measurement of CBC, non-fasting cholesterol profile, high sensitivity C-reactive protein (hs-CRP) and malondialdehyde (MDA) were performed in 71 CKD patients grouped into hemodialysis (HD) and non-hemodialysis (non-HD). Correlation analysis were performed to assess the potential of CBC and cholesterol profile to describe the level of hs-CRP and MDA.RESULTS: In the HD group, total cholesterol was moderately associated with hs-CRP while total cholesterol/HDL-C ratio, monocyte/HDL-C ratio, monocyte/LDL-C ratio, neutrophil/HDL-C ratio, neutrophil/LDL-C ratio, platelet/HDL-C ratio and platelet/LDL-C ratio were strongly associated with hs-CRP. In the non-HD group,only neutrophil/total cholesterol ratio and platelet/total cholesterol ratio that were associated with hs-CRP. Total cholesterol, monocyte/LDL-C ratio, neutrophil/LDL-C ratio and platelet/LDL-C ratio were moderately associated with MDA while total cholesterol/HDL-C ratio, monocyte/HDL-C ratio, neutrophil/HDL-C ratio and platelet/HDL-C ratio were strongly associated respectively with MDA in HD group. In the non-HD group, total cholesterol/HDL-C ratio, neutrophil/HDL-C ratio and platelet/HDL-C ratio were moderately associated with MDA in non-HD group while monocyte/HDL-C ratio was weakly associated with MDA.CONCLUSION: Some CBC parameters and non-fasting cholesterol profile such as cholesterol/HDL-C, monocyte/HDL-C, neutrophil/HDL-C and platelet/HDL-C ratio showed a potential to describe the inflammation and stress oxidative markers, given some strong associations with the level of hs-CRP and MDA. Further study is needed to assess whether this parameter represent long-term prognostic value among CKD patients.KEYWORDS: inflammation, oxidative stress, CRP, MDA, TAC, 8-OHdG, CBC, cholesterol

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Lakshmy, R., R. Gupta, D. Prabhakaran, U. Snehi und K. S. Reddy. „Utility of Dried Blood Spots for Measurement of Cholesterol and Triglycerides in a Surveillance Study“. Journal of Diabetes Science and Technology 4, Nr. 2 (01.03.2010): 258–62. http://dx.doi.org/10.1177/193229681000400206.

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Magfirah, Indah Kurnia Utami und Syafika Alaydrus. „Effect of Seaweed Ethanol Extract on Cholesterol Levels and Obesity in White Rats“. Jurnal Jamu Indonesia 5, Nr. 3 (16.11.2020): 98–105. http://dx.doi.org/10.29244/jji.v5i3.175.

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Seaweed (EucheumaCottonii J. Agardh) is one of the biological resources found in coastal and marine areas. Seaweed contains secondary metabolites such as flavonoids, alkaloids, polyphenols and tannins which can reduce cholesterol levels in the blood. This study aims to determine the effect of seaweed ethanol extract on reducing cholesterol and obesity levels by comparing plasma cholesterol levels, body weight, and weight of vital organs (liver, kidneys and jantumg) of obese rats, mice given seaweed ethanol extract with normal mice . Rats were grouped randomly into 6 groups. group one was given 0.5% CMC Na, group two was given high fat diet food, group three was given simvastatin, group four was given seaweed ethanol extract 100 mg / kgbb, group five was given ethanol extract of seaweed 200 mg / kgbb and group six was given ethanol extract of seaweed 300 mg / kg with a long suspension of extract for 14 days. Measurement of cholesterol levels in the blood using the CHOD-PAP method, body weight and organs carried out by weighing. The results showed that seaweed ethanol extract has the effect of inhibiting an increase in plasma cholesterol levels and has anti-obesity potential at a dose of 300 mg / kgbb.

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