Thematische Bibliographien / Masaryk Institute of Oncology

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Auswahl der wissenschaftlichen Literatur zum Thema „Masaryk Institute of Oncology“

Autor: Grafiati

Veröffentlicht am 28. Juni 2021

Zuletzt aktualisiert am 17. Februar 2022

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Zeitschriftenartikel zum Thema "Masaryk Institute of Oncology"

Macháčková, Eva, Jana Házová, Eva Sťahlová Hrabincová, Petra Vašíčková, Marie Navrátilová, Marek Svoboda und Lenka Foretová. „Retrospective NGS Study in High-risk Hereditary Cancer Patients at Masaryk Memorial Cancer Institute“. Klinicka onkologie 29, Suppl 1 (15.01.2016): S35—S45. http://dx.doi.org/10.14735/amko2016s35.

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Pešová, Zdeňka, Monika Náležinská, Marie Dvořáková, Jana Kocurková und Josef Chovanec. „Ostacles of the daily care of patients with permanent urine catether following radical gynae-oncological surgical procedure in Masaryk Memorial Cancer Institute, Brno, Czech Republic“. Onkologie 14, Nr. 2 (02.06.2020): 100–102. http://dx.doi.org/10.36290/xon.2020.019.

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Grell, Peter, Vit Kandrnal, Bortlicek Zbynek und Rostislav Vyzula. „Lapatinib efficacy according to metastatic sites in trastuzumab pretreated patients with HER2-positive metastatic breast cancer: An analysis form IntERB registry in the Czech Republic.“ Journal of Clinical Oncology 30, Nr. 15_suppl (20.05.2012): e11072-e11072. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e11072.

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e11072 Background: Lapatinib is an oral dual tyrosin kinase inhibitor of EGFR and HER2 and compared to trastuzumab penetrates to CNS. We evaluated efficacy and safety of lapatinib treatment according to different metastatic sites involvement using data from IntERB registry that has been initiated and run by Czech Society for Oncology and Institute of Biostatistics and Analyses at Masaryk University, Brno, Czech Republic. Methods: An analysis included 213 patients with HER2 positive metastatic breast cancer treated from January 2007 to September 2011. Lapatinib was mostly administered orally 1250mg/day with capecitabine (2000mg/m2 D1-14), 16 patients received lapatinib in monotherapy. All patients had experienced progression during prior trastuzumab based therapy. Results: Median age was 56 years (range 23 – 78). Median duration of lapatinib therapy was 20.6 weeks (range 1–146). Complete response was achieved in 13 patients (6.1%), partial response in 31 (14.6%), stable disease in 118 (55.4%). In 26 disease have progressed (12.2%); response could not be assessed in 25 patients (11.7%). PFS for whole group was 7.1 months (95% CI 5.9-8.5). Overall survival was 17.2m (95% CI 15.8-18.6), probability of 6m OS was 80.3% and 1-year OS was 64%. Metastatic sites specific survival was evaluated in 103 patients. CNS dissemination was initially diagnosed in 31 patients (30.1%), PFS in this group was 6.2m (95% CI 3.3-9.1), OS was not reached, 6-m OS was 67.3%. In non-CNS group (skeletal metastasis in 49.5%, lung 38.8%, hepatic 36.9%, lymphatic 17.5%, other 15.5%) was PFS 6.3m (95% CI 1.6-11.1), OS 22.0m (95% CI 15.3-28.8) and 6-m OS was 88.2%. Most common toxicities were diarrhea in 11.7% patients, rash/skin toxicity in 10.8%, nausea/vomitus in 5.2% and hepatotoxicity in 2.3%. No cardiac toxicity was reported. Therapy was discontinued due toxicity in 9.0%. Conclusions: Lapatinib in combination with capecitabine proved its efficacy in trastuzumab pretreated HER2 positive metastatic breast cancer. Even in patients with CNS involvement was achieved a notable PFS and OS, comparable to non-CNS group of patients. Therapy was well tolerated.

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Hasnikova, Hana, und Petr Kuklík. „Investigation of Timber Members at the Marasyk Station in Prague by Non-Destructive Methods“. Advanced Materials Research 778 (September 2013): 243–49. http://dx.doi.org/10.4028/www.scientific.net/amr.778.243.

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The Masaryk Railway Station is the oldest still working terminal railway station in Europe. It was built in 1845 and the buildings belonged to the most splendid railway stations in that time. During the long life the part of Masaryk Station burned, it was also damaged while World Wars and finally large reconstruction started last year. The buildings have a high historical value, so the specialists from National Heritage Institute wanted all the original structural members to be preserved. The structure was constructed from two wooden species spruce and fir. Selected timber elements were tested by various non-destructive methods to assess their health. Pilodyn, a device with iron stick can assess a material quality using correlation between depth of stick indentation and material strength. Sylvatest device operates with ultrasonic waves and can determine dynamic modulus of elasticity as one of the mechanical characteristics. Dynamoe device uses an acoustic wave to assess the material quality. The aim of the paper is to present the procedure of timber testing and to discuss measured results.

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Mlejnková, Hana, und Zdenka Žáková. „Use of microbiological and biological methods for monitoring the influence of diffuse pollution on reservoir's water quality“. Water Science and Technology 33, Nr. 4-5 (01.02.1996): 341–47. http://dx.doi.org/10.2166/wst.1996.0524.

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The research results of water supply reservoirs and their tributaries in the Morava River basin showed the important role of the biological and microbiological investigations by monitoring the influence of diffuse pollution on the reservoir's water quality. Our report brings the critical evaluation of the possibility to use some microbiological and biological methods by monitoring of diffuse pollution, it also includes some practical results received from monitoring the streams and reservoirs within the Morava River basin (in the frame of research projects of the T. G. Masaryk Water Research Institute, branch office Brno).

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Hauner, Milan. „Dagmar Hájková, and Šedivý Ivan, eds. Korespondence T.G. Masaryk—Edvard Beneš, 1914–1918. Prague: Masaryk Institute of the Academy of Sciences of the Czech Republic, 2004. Pp. 353.“ Austrian History Yearbook 37 (Januar 2006): 234–35. http://dx.doi.org/10.1017/s0067237800017008.

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Montel, Christopher. „Role amerických a francouzských spolupracovníků v mezinárodní strategii redakčního týmu Sociologické revue ve 30. letech“. Sociální studia / Social Studies 17, Nr. 2020 SPEC (18.12.2020): 53–68. http://dx.doi.org/10.5817/soc2020-s-53.

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Three French sociologists (Bouglé, Duprat and Richard), as well as three sociologists from the United States (Hasek, Rouček and Sorokin), exclusively represented Western sociology in a list of nine foreign collaborators, which featured from 1933 to 1940 on the first page of the Czech periodical Sociologická revue. Duprat and Richard were evidently included in this list at a time when the Masaryk Sociological Society, whose publishing organ was the Sociologická revue, played a significant role in the resumed activities of the International Institute of Sociology. The collaboration of the three “American” sociologists was more participative. It answered the urgent need, according to the revue’s redacting team, to inform readers on the latest developments in the field from America. The names of Bouglé, and above all Sorokin, undoubtedly represented in this list a symbolic advantage for the revue’s redacting team and its international strategy.

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McNamee, David. „European Institute of Oncology opens“. Lancet 343, Nr. 8910 (Juni 1994): 1424. http://dx.doi.org/10.1016/s0140-6736(94)92545-3.

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Topuz, Erkan, und Inci Ayan. „University of Istanbul, Institute of Oncology“. Pediatric Hematology and Oncology 14, Nr. 4 (Januar 1997): 315–21. http://dx.doi.org/10.3109/08880019709041591.

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Mełgieś, Katarzyna. „CURRENT HEALTH LAW ISSUES IN CENTRAL AND EASTERN EUROPE(LUBLIN, 3 JUNE 2016, CONFERENCE REPORT)“. Review of European and Comparative Law 2627, Nr. 34 (31.12.2019): 225–29. http://dx.doi.org/10.31743/recl.5077.

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On 3 June 2016 an international conference on Current Health Law Issues in Central and Eastern Europe took place at the John Paul II Catholic University of Lublin. The conference was organised by the Department of Administrative Law at the Faculty of Law, Canon Law and Administra-tion under the honorary patronage of the European Association of Health Law (EAHL). The aim of the above-mentioned meeting was to create the platform for exchange of experiences and sharing views by researches and experts from the field of health law from post-communist countries where transformation processes caused many changes in the health system, also in the perspective of their EU memberships. The foreign research centres represented at the conference were the Masaryk University in Brno from the Czech Republic, the National Academy of Management in Kiev and the Legislation Institute of Verkhovna Rada of Ukraine from Ukraine, the University of Ljubljana from Slovenia, and the Kauno Kolegija University of Applied Sciences from Lithuania. Polish speakers and other participants derived, among others, from the Medical University of Lublin, the Jagiel-lonian University, the University of Rzeszów and the John Paul II Catholic University of Lublin.

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Dissertationen zum Thema "Masaryk Institute of Oncology"

Halenková, Kateřina. „Aplikace radiofrekvenční technologie na Masarykově onkologickém ústavu“. Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-9549.

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The first part introduces the RFID technology and its application in the healthcare and pharma. The second part deals with the particular RFID application in the process of preparation and aplication of cytostatics at MOU. It includes process analysis, identification of areas where there is a lack in usage of technology potential, suggestions on how to increase the benefits of the implementation, as well as identification of factors that have impact on the valuation of RFID projects.

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Palomino, Sánchez Juan David. „Instituto Oncológico Pediátrico en San Juan de Lurigancho“. Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/656708.

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El desarrollo físico y emocional de las personas empieza en la etapa de la niñez, es por ello, que es necesario enfatizar en la salud física y psicológica de los niños. El Instituto Oncológico Pediátrico se da como respuesta a la necesidad de salud pública que se ve en el país. No obstante, es necesario diferenciar el tratamiento que se da en un niño y un adulto para obtener mejores resultados. El presente proyecto mediante una simbiosis entre la arquitectura y el uso del énfasis arquitectónico “neuroarquitectura”, genera espacios intermedios donde los pacientes puedan recuperarse de forma psicológica y física. Es por ello que el proyecto toma como objetivo principal la importancia de que los niños tengan acceso a establecimientos de salud con espacios eficientes que mejoren la autoestima de los niños. Esto se ve a través de la iluminación y ventilación natural, ambientes para la integración y el encuentro entre los niños y familiares. Sin perder la funcionalidad de un hospital debido a su alto nivel de complejidad.
The physical and emotional development of people begins at the childhood stage, which is why it is necessary to emphasize the physical and psychological health of children. The Pediatric Oncology Institute is created in response to the need for public health seen in the country. However, it is necessary to differentiate the treatment given to a child or an adult to obtain better results. The present project, through a symbiosis between architecture and the use of the architectural emphasis “neuroarchitecture”, generates intermediate spaces where patients can recover psychologically and physically, Therefore the main project’s objective is the importance of children having access to health facilities with efficient spaces that improve children's self-esteem. This is achieved through natural lighting and ventilation, meeting areas for children and their families without losing the functionality of a hospital due to its high level of complexity.
Tesis

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Munivenkata, Swamy Preethi. „Combined CTLA-4 and PD-1 inhibition a single institute in-depth analysis of toxicity and efficacy in patients treated at the Dana-Farber Cancer Institute“. Thesis, 2017. https://hdl.handle.net/2144/26950.

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PURPOSE: The purpose of this study was to compare the rate of grade 3-4 immune related adverse events (irAEs) in patients with advanced metastatic melanoma treated with the combined anti-CTLA-4 and anti-PD-immune-therapy at the Dana Farber Cancer Institute(DFCI), to that of the published rate of grade 3-4 irAEs among patients treated with the same combination of check-point therapy in the pivotal phase II and phase III trials that led to the FDA approval of the combination regimen. This study also measures the tumor response with the Ipi-Nivo combination therapy and overall-survival of patients in the study cohort at DFCI. METHODS/PROCEDURES: This is a retrospective cohort study conducted at DFCI during 2014 to 2016 among stage III/IV melanoma patients treated outside of the clinical trials with the Ipi-Nivo combination therapy. Chart review of the electronic medical record(EMR) was conducted to abstract the data for this study. irAEs were graded and classified as per the NCI-CTCAE v.4.0 guidelines. The comparison of the rate of grade 3 4 toxicity in the clinical settings at DFCI and the clinical trials was performed using a one sample proportion hypothesis test. For efficacy assessment of tumor response, RECIST1.1 criterion was used to ascertain the best clinical response. RESULTS: During an overall follow-up period of 600 days, 52 patients were treated on expanded access protocol (EAP) and commercial Ipi-Nivo combination therapy at DFCI. The rate of grade 3-4 immune mediated toxicity for this cohort of patients treated outside of clinical trials was 32.6%. The average rate of grade 3-4 irAEs reported in phase II/III clinical trials was approximately 55%. The results from the one-proportion hypothesis test [(P-value: 0.002) (95% C.I: 19.14-46.23)], prove that patients in the “real world” clinical settings have a different safety profile than patients treated in the clinical trials. The rate of grade 3-4 irAEs was found to be lower (19.14% to 46.23%) in the population treated with Ipi/Nivo combination therapy at the DFCI, compared to the check-mate clinical trials (approximately 55%) CONCLUSION: The results from the study indicate a lower rate of grade 3-4 irAEs in patients treated at DFCI, in comparison with the patients treated in the clinical trials for the Ipi-Nivo combination group. The results support the need for preemptive safety signal detection of symptoms of irAEs to improve patient’s safety. However, larger database studies are required for the generalizability of this results to a wider patient population treated outside of DFCI.

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Hanson, Christopher S. „The Institute of Medicine's 2001 report on palliative cancer care as an instrument of innovation in palliative oncology“. 2007. http://hdl.rutgers.edu/1782.2/rucore10001600001.ETD.16072.

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Kazimourová, Veronika. „Klíčové myšlenky lidovýchovné koncepce Tomáše Trnky“. Master's thesis, 2020. http://www.nusl.cz/ntk/nusl-436622.

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This thesis deals with the key ideas of the popular education concept of Professor Tomáš Trnka, who is considered to be a leading theorist of popular education in the interwar Czechoslovakia, and who has significant merits in the gradual constitution of andragogy as an independent scientific discipline. The main focus of the thesis is on the analysis of his key publications The Basics of Popular Education (published in 1934) and Popular Education, its theory, components, methods and organization (published in 1946). The text aims to provide a comprehensive overview of Trnka's work in the field of popular education, with regards to relevant andragogical and historical contexts. The thesis also contains a critical evaluation of Trnka's work and a reflection of its development in the following historical periods. Key words: Tomáš Trnka, popular education, public education, Masaryk Institute for Popular Education, interwar Czechoslovakia, content analysis

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Bücher zum Thema "Masaryk Institute of Oncology"

Tıp, Fakültelerinde Mezuniyet Öncesi Onkoloji Eğitimi Simpozyumu (1984 Ankara Turkey). Tıp Fakültelerinde Mezuniyet Öncesi Onkoloji Eğitimi Simpozyumu: 4 Kasım 1984, Hacettepe Üniversitesi Onkoloji Enstitüsü = Symposium on Undergraduate Oncology Education in Medical Schools : November 4, 1984, University of Hacettepe, Institute of Oncology, Ankara. Ankara: Türk Kanser Araştırma ve Savaş Kurumu, 1985.

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Boggs, Dale. Working together: The Medicine Branch, the health care team, and you. [Bethesda, Md.?]: U.S. Dept. of Health and Human Services, Public Health Service, National Institutes of Health, Clinical Center, 1990.

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E, Mortenson Lee, Engstrom Paul F. 1936-, Anderson Paul N und Association of American Cancer Institutes., Hrsg. Advances in cancer control: Health care financing and research : proceedings of the Association of Community Cancer Centers 11th National Meeting, Oncology--surviving the 80's : a combined meeting of the Association of American Cancer Centers/Association of American Cancer Institute, held in Washington, D.C., March 13-17, 1985. New York: Liss, 1986.

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Papini, Massimo, Hrsg. L'ultima cura. Florence: Firenze University Press, 2010. http://dx.doi.org/10.36253/978-88-8453-457-6.

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This book is the outcome of a new method of investigating the life experiences of health personnel engaged in paediatric oncology. It brings together the results of individual interviews with each member of the medical, nursing and technical staff in the Paediatric Oncology Department of the University Polyclinic of Padua and the Giannina Gaslini Institute of Genoa. The interviews, prepared using an open questionnaire format, were carried out by qualified personnel, after which the results were analysed and illustrated to the group of health care professionals involved. The two experiences, which are extremely significant in view of the distinction of the two centres of excellence involved, are compared and discussed with a view to making an interesting contribution to the debate on the delicate issues of bioethics implicated in problems connected with the end of life during the developmental stage.

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Bennett, James T. Cancer Scam: Diversion of federal cancer funds to politics. New Brunswick, N.J: Transaction Publishers, 1998.

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Thoracic oncology section. [Bethesda, Md.?]: National Cancer Institute, 2000.

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1935-, Skarin Arthur T., und Dana-Farber Cancer Institute, Hrsg. Dana-Farber Cancer Institute atlas of diagnostic oncology. Philadelphia: Lippincott, 1991.

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1935-, Skarin Arthur T., und Dana-Farber Cancer Institute, Hrsg. Dana-Farber Cancer Institute atlas of diagnostic oncology. 2. Aufl. London: Mosby-Wolfe, 1996.

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National Cancer Institute (U.S.), Hrsg. Urologic Oncology Research Fellowship Training Program at the National Cancer Institute. [Bethesda, Md.]: National Institutes of Health, National Cancer Institute, 1999.

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Buchteile zum Thema "Masaryk Institute of Oncology"

Boiko, A. V., A. V. Chernichenko, V. I. Chissov und V. A. Kvasov. „IORT in P.A. Ghertsen Oncological Institute: Reality and Perspectives“. In Frontiers of Radiation Therapy and Oncology, 80–83. Basel: KARGER, 1997. http://dx.doi.org/10.1159/000061150.

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Dickherber, Anthony, Shannon K. Hughes und Nastaran Zahir. „The National Cancer Institute Investment in Biomechanics in Oncology Research“. In Advances in Experimental Medicine and Biology, 1–10. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-95294-9_1.

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Schiavone, Francesco, Luca Dezi und Daniele Leone. „Elderly Entrepreneurs in Healthcare: The Case of the European Institute of Oncology (IEO)“. In Handbook of Research on Elderly Entrepreneurship, 175–87. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-13334-4_11.

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Casar, B., I. Vojvodic, V. Robar, U. Smrdel und I. Mendez Carot. „New system for TBI with translation method at the Institute of Oncology Ljubljana“. In IFMBE Proceedings, 996–97. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03474-9_279.

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Mello, Josiane, und Angel Freddy Godoy Viera. „Proposal of Model for Curation Digital Objects of an Oncology Research Center“. In Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, 235–49. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-50072-6_18.

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Hunter, Carrie P. „Cancer Control and the Community Oncology Programs: Minority Participation in the National Cancer Institute Clinical Trials Network“. In Minorities and Cancer, 95–101. New York, NY: Springer New York, 1989. http://dx.doi.org/10.1007/978-1-4612-3630-6_8.

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„National Cancer Institute Resources for AIDS Oncology Research“. In AIDS-Related Cancers and Their Treatment. Informa Healthcare, 2000. http://dx.doi.org/10.1201/9780203909645.ch18.

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„National Cancer Institute Resources for AIDS Oncology Research“. In AIDS-Related Cancers and Their Treatment, 403–17. CRC Press, 2000. http://dx.doi.org/10.1201/b14829-19.

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Holland, Jimmie C., und Talia R. Weiss. „The New Standard of Quality Cancer Care in the US: The Institute of Medicine (IOM) Report, Cancer Care for the Whole Patient: Meeting Psychosocial Needs“. In Psycho-Oncology, 666–74. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780195367430.003.0097.

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Fitzgibbon, Marian L., Lisa Tussing-Humphreys, Angela Kong und Alexis Bains. „Diet and Cancer“. In Psycho-Oncology, herausgegeben von Paul B. Jacobsen, 13–20. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190097653.003.0003.

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Diet contributes to the development of 30% to 35% of cancers. Shifts in the food landscape have contributed to changes in dietary intake, energy balance, and the development of obesity. Obesity, defined as a body mass index (BMI) greater than or equal to 30 kg/m², is associated with several cancers. The World Cancer Research Fund (WCRF), the American Institute for Cancer Research (AICR), the American Cancer Society (ACS), and several large U.S.-based randomized trials are studying the relationship between diet, dietary patterns, lifestyle risk factors, obesity, and cancer. Prior research reported an association between individual nutrients and cancer risk. This research, however, did not fully investigate the complexity of diet and interactions between specific dietary components. Overall, according to data reported by the WCRF and the AICR, primary prevention of many cancers is possible through modifiable lifestyle changes. Identifying and intervening on barriers to lifestyle modifications remains a challenge, but it is increasingly apparent that there is a relationship between diet, lifestyle risk factors, and cancer development and that many cancers can be prevented.

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Konferenzberichte zum Thema "Masaryk Institute of Oncology"

Aggarwal, Abhinav. „Cystic adnexal lesion on USG – causing a diagnostic dilemma in oncology institute“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685317.

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Adnexal lesions are one of the most common cause of gynecological complains, including possibility of ectopic pregnancy in reproductive age group. Ultrasound is the first imaging modality used for evaluation of adnexal lesions. On ultrasound large non-adnexal lesions can be confused as adnexal lesions causing a diagnostic dilemma, rendering use of cross-sectional imaging mandatory. We present a case of middle-aged female who was diagnosed with a right adnexal lesion (possibly malignant) on ultrasound, but on further evaluation was found to be suffering from a benign non-adenexal etiology.

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Shern, Jack, Joanna Selfe, Rajesh Patidar, Young Song, Marielle Yohe, Jun Wei, Xinyu Wen et al. „Abstract B15: Genomic classification and prognosis in rhabdomyosarcoma: A report from the Children’s Oncology Group, the Institute of Cancer Research, and the National Cancer Institute“. In Abstracts: AACR Special Conference on the Advances in Pediatric Cancer Research; September 17-20, 2019; Montreal, QC, Canada. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.pedca19-b15.

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Keller, Rachel B., Tali Mazor, Marios Giannakis, Jonathan Nowak, Lynette Sholl, Andrew Aguirre, Adam Bass et al. „Abstract C130: Precision oncology decision support within the Gastrointestinal Cancer Center at Dana-Farber Cancer Institute (GI TARGET)“. In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c130.

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Wong, Chris, Constance Barysauskas, Marie Desrochers, Margaret Brill-Conway, Riley Mahan, Kelly Eng und Amy Billett. „886 A quality improvement program to achieve independence in home central line care by paediatric oncology families“. In Institute for Healthcare Improvement (IHI) Scientific Symposium on Improving the Quality and Value of Health Care. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/bmjoq-2017-ihi.7.

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Scollon, Sarah, Sharon E. Plon, Steven Joffe, Jaclyn A. Biegel, Shashikant Kulkarni, George Miles, David Patton et al. „Abstract 631: Germline cancer predisposition results from the National Cancer Institute - Children's Oncology Group (NCI-COG) Pediatric MATCH Trial“. In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-631.

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Stone, Christopher, Erin Brown, Mihaela Mates, Conrad Falkson, Timothy Owen, Allison Ashworth, Aamer Mahmud, Christopher Parker, Andrew Robinson und Genevieve Digby. „916 Evaluation of a multidisciplinary cancer clinic: improving time to oncology assessment and treatment for patients with new lung cancer“. In Institute for Healthcare Improvement (IHI) Scientific Symposium on Improving the Quality and Value of Health Care. British Medical Journal Publishing Group, 2017. http://dx.doi.org/10.1136/bmjoq-2017-ihi.12.

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Franco, AC, und A. Gouveia. „2SPD-017 Impact of the implementation of the falsified medicines directive at the Lisbon Portuguese Institute of Oncology (FG, EPE)“. In 25th EAHP Congress, 25th–27th March 2020, Gothenburg, Sweden. British Medical Journal Publishing Group, 2020. http://dx.doi.org/10.1136/ejhpharm-2020-eahpconf.36.

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Aftimos, Philippe G., Marion Maetens, Françoise Rothé, David Brown, Yacine Barèche, Alexandre Irrthum, Thierry Berghmans et al. „Abstract 3962: Circulating tumor DNA (ctDNA) as an alternative to tumor biopsies for precision oncology: The Jules Bordet Institute experience“. In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3962.

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Arora, Ruchi. „Role of intraoperative frozen section in the diagnosis of ovarian tumors: Experience at Gujarat Cancer and Research Institute“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685318.

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Background: The surgical management of ovarian tumors depends on their correct categorization as benign, borderline or malignant. Ovarian neoplasms are an important cause of morbidity and mortality in women. This study was undertaken to evaluate the accuracy of intra-operative frozen section in the diagnosis of various categories of ovarian neoplasms. Methods: Intraoperative frozen section diagnosis was retrospectively evaluated in 125 patients with suspected ovarian neoplasms who underwent surgery as primary line of therapy at our institution. This was compared with the final histopathologic diagnosis on paraffin sections. Results: In 125 patients frozen section report had a sensitivity of 100%, 95.55% and 50% for benign, malignant and borderline tumors respectively. The corresponding specificities were 92.45%, 98.75% and 99.14% respectively. The overall accuracy of frozen section diagnosis was 95.2%. The majority of cases of disagreement were in the mucinous and borderline tumors. Conclusion: Intraoperative frozen section has high accuracy in the diagnosis of suspected ovarian neoplasms. It is a valuable tool to guide the surgical management of these patients and should be routinely used in all major oncology centers.

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Devi, Pinki, Ganapathi Bhat und Harish S. Ahuja. „To Predict Success of Postapheresis Yield and Post–Autologous Transplant Engraftment Based on Preapheresis Peripheral Blood CD34+ Cell Counts: An Indian Scenario–Based Study“. In Annual Conference of Indian Society of Medical and Paediatric Oncology (ISMPO). Thieme Medical and Scientific Publishers Pvt. Ltd., 2021. http://dx.doi.org/10.1055/s-0041-1735370.

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Abstract Introduction The use of hematopoietic stem cells for autologous and allogeneic transplantation has increased in the recent past significantly, due to introduction of newer chemotherapeutic drugs, immunological techniques, and better stem cell technology. Among the bone marrow and peripheral blood stem cells, collection of the latter being more convenient to the patient and associated with faster granulocyte and platelet engraftment has been known as preferred method for mobilization. Peripheral blood stem cells can be extracted from the autologous or allogeneic donor. Mobilization of the stem cells for autologous stem cell transplant is traditionally done using growth factors alone or in combination with chemotherapy, with or without an additional mobilizing agent. A significant number of hematological malignancy patients are poor mobilizers, (i.e., they are unable to achieve the minimal target cell dose during their first round of mobilization).Therefore, a prediction for a successful stem cell mobilization ideally should be made before initiating any apheresis procedure to spare those with a low rate of success from the risks associated with apheresis procedure. Preapheresis CD34 cell count can predict postapheresis yield and hence, can help to reduce the collection sessions. Reduction of apheresis sessions decreases the discomfort, inconvenience, time, and monetary expenses. Objectives This study was aimed to analyze preapheresis and postapheresis CD34+ cell counts. Materials and Methods Patients of any age and gender with diagnosis of hematological malignancies admitted for autologous stem cell transplantation for hematological malignancies (including Hodgkin lymphoma, non-Hodgkin lymphoma, and multiple myeloma) and germ cell tumors in our institute from July 2008 to July 2016 were included in the study. The post-GCSF CBC, preapheresis CBC, CD34+ cell counts, and postapheresis CBC, CD34+ cell counts, mononuclear cell counts to predict the outcome of amount of yield. The effect on engraftment will be measured according to the defining criteria of achieving a sustained peripheral blood neutrophil count of >500 × 106/L (Wolff 2002) and a platelet count of more than >20 × 109/L (Teltschik et al. 2016) independent of platelet transfusion for at least 7 days. Collection of stem cells was done using apheresis machine (COBE SPECTRA). Complete peripheral blood counts using automated analyzers. Peripheral blood CD34 + cell counts and postapheresis CD34+ cell count using BD FACS CANTO II flow cytometer. To calculate postapheresis yield, the related CD34 count measured by flow cytometer was multiplied by the apheresis product volume and divided by the recipient’s body weight (kg). Number of CD34+ cells collected = (CD34 cell concentration in final product) × (final product volume). Results A total of 100 patients who underwent a total of 320 apheresis sessions were included in the study. There were 78 males and 22 females. We also found a significant correlation between preapheresis CD34 + cell count and postapheresis CD34 percentage on days 1, 2, and 3 of the apheresis sessions. In our study, to obtain more than 1.31 × 106 cells (median = 1.04, range: 0.15–4.70), an absolute count of pre apheresis CD34 + cells ≥14 cells would be necessary. A target of CD34 + cells ≥ 2 × 106/kg was obtained in majority of patients if a concentration of ≥25 CD34 + cells was present in postapheresis collection. Conclusion Compiling our results with the previous published data, we conclude that there is a strong correlation between preapheresis absolute CD34 + cell counts and postapheresis CD34 + cell count. Our study also suggests that the minimum absolute cell count of >10 cells/μL is required, to achieve a target of >2–5 × 106 cells for postapheresis yield.

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