Thematische Bibliographien / Lin-3

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Auswahl der wissenschaftlichen Literatur zum Thema „Lin-3“

Autor: Grafiati
Veröffentlicht am 25. Mai 2024

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Zeitschriftenartikel zum Thema "Lin-3"

1

Liu, Jing, Phoebe Tzou, Russell J. Hill und Paul W. Sternberg. „Structural Requirements for the Tissue-Specific and Tissue-General Functions of the Caenorhabditis elegans Epidermal Growth Factor LIN-3“. Genetics 153, Nr. 3 (01.11.1999): 1257–69. http://dx.doi.org/10.1093/genetics/153.3.1257.

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Abstract Caenorhabditis elegans lin-3 encodes a homolog of the epidermal growth factor (EGF) family of growth factors. LIN-3 is the inductive signal for hermaphrodite vulval differentiation, and it is required for animal viability, hermaphrodite fertility, and the specification of anterior cell fates in the male B cell lineage. We describe the cloning of a lin-3 homolog from C. briggsae, sequence comparison of C. elegans lin-3 with C. briggsae lin-3, and the determination of molecular lesions in alleles of C. elegans lin-3, including three new alleles. We also analyzed the severity of phenotypes caused by the new and existing alleles of lin-3. Correlation of mutant phenotypes and their molecular lesions, as well as sequence comparison between two species, reveal that the EGF motif and the N-terminal portion of the cytoplasmic domain are important for the functions of LIN-3 in all tissues, while the C-terminal portion of the cytoplasmic domain is involved in the tissue-specific functions of lin-3. We discuss how the structure of lin-3 contributes to its functions in multiple developmental processes.
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2

Jiang, L. I., und P. W. Sternberg. „Interactions of EGF, Wnt and HOM-C genes specify the P12 neuroectoblast fate in C. elegans“. Development 125, Nr. 12 (15.06.1998): 2337–47. http://dx.doi.org/10.1242/dev.125.12.2337.

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We investigate how temporal and spatial interactions between multiple intercellular and intracellular factors specify the fate of a single cell in Caenorhabditis elegans. P12, which is a ventral cord neuroectoblast, divides postembryonically to generate neurons and a unique epidermal cell. Three classes of proteins are involved in the specification of P12 fate: the LIN-3/LET-23 epidermal growth factor signaling pathway, a Wnt protein LIN-44 and its candidate receptor LIN-17, and a homeotic gene product EGL-5. We show that LIN-3 is an inductive signal sufficient to promote the P12 fate, and the conserved EGF signaling pathway is utilized for P12 fate specification; egl-5 is a downstream target of the lin-3/let-23 pathway in specifying P12 fate; and LIN-44 and LIN-17 act synergistically with lin-3 in the specification of the P12 fate. The Wnt pathway may function early in development to regulate the competence of the cells to respond to the LIN-3 inductive signal.
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3

Keller, JR, JM Gooya und FW Ruscetti. „Direct synergistic effects of leukemia inhibitory factor on hematopoietic progenitor cell growth: comparison with other hematopoietins that use the gp130 receptor subunit“. Blood 88, Nr. 3 (01.08.1996): 863–69. http://dx.doi.org/10.1182/blood.v88.3.863.863.

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Abstract Because leukemia inhibitory factor (LIF) has little or no effect on murine hematopoietic progenitor cell growth yet enhances hematopoiesis in vivo, we sought to determine whether the effects of LIF were directly or indirectly mediated, or a combination of both. Although LIF alone or in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) or interleukin-3 (IL-3) has no effect on colony formation of unfractionated bone marrow cells (BMCs), it enhances M-CSF- induced colony formation. In comparison, LIF synergizes with IL-3, GM- CSF, M-CSF, and Steel Factor (SLF) to promote the colony formation of partially purified lineage-negative (Lin-) BM progenitors without altering their differentiation. These effects were directly mediated since identical results were observed in single-cell assays. Comparing the effect of LIF with other members of this subclass of hematopoietins (IL-6, oncostatin M [OSM], and ciliary neurotrophic factor [CNTF]), we found that while LIF and IL-6 equally synergize with M-CSF and SLF to promote the colony formation of Lin- BMCs, OSM, and CNTF have no effect. In agreement with OSMs ability to directly bind gp130, preincubation of BMCs with OSM inhibits progenitor cell growth stimulated by the combination of LIF or IL-6 plus SLF. LIF can also directly enhance the growth of further purified more primitive Lin- c- kit+ progenitor cells in the presence of IL-3, GM-CSF, or SLF. Thus, LIF can directly synergize with growth factors to promote the proliferation of purified hematopoietic progenitors, suggesting that the direct effects of LIF on hematopoietic cell growth can, in part, explain the observed hematopoietic effects in vivo. This is a US government work. There are no restrictions on its use.
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4

Keller, JR, JM Gooya und FW Ruscetti. „Direct synergistic effects of leukemia inhibitory factor on hematopoietic progenitor cell growth: comparison with other hematopoietins that use the gp130 receptor subunit“. Blood 88, Nr. 3 (01.08.1996): 863–69. http://dx.doi.org/10.1182/blood.v88.3.863.bloodjournal883863.

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Because leukemia inhibitory factor (LIF) has little or no effect on murine hematopoietic progenitor cell growth yet enhances hematopoiesis in vivo, we sought to determine whether the effects of LIF were directly or indirectly mediated, or a combination of both. Although LIF alone or in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF) or interleukin-3 (IL-3) has no effect on colony formation of unfractionated bone marrow cells (BMCs), it enhances M-CSF- induced colony formation. In comparison, LIF synergizes with IL-3, GM- CSF, M-CSF, and Steel Factor (SLF) to promote the colony formation of partially purified lineage-negative (Lin-) BM progenitors without altering their differentiation. These effects were directly mediated since identical results were observed in single-cell assays. Comparing the effect of LIF with other members of this subclass of hematopoietins (IL-6, oncostatin M [OSM], and ciliary neurotrophic factor [CNTF]), we found that while LIF and IL-6 equally synergize with M-CSF and SLF to promote the colony formation of Lin- BMCs, OSM, and CNTF have no effect. In agreement with OSMs ability to directly bind gp130, preincubation of BMCs with OSM inhibits progenitor cell growth stimulated by the combination of LIF or IL-6 plus SLF. LIF can also directly enhance the growth of further purified more primitive Lin- c- kit+ progenitor cells in the presence of IL-3, GM-CSF, or SLF. Thus, LIF can directly synergize with growth factors to promote the proliferation of purified hematopoietic progenitors, suggesting that the direct effects of LIF on hematopoietic cell growth can, in part, explain the observed hematopoietic effects in vivo. This is a US government work. There are no restrictions on its use.
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5

Chamberlin, H. M., und P. W. Sternberg. „The lin-3/let-23 pathway mediates inductive signalling during male spicule development in Caenorhabditis elegans“. Development 120, Nr. 10 (01.10.1994): 2713–21. http://dx.doi.org/10.1242/dev.120.10.2713.

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During Caenorhabditis elegans male spicule development, four pairs of precursor cells respond to multiple positional cues and establish a pattern of fates that correlates with relative anterior-posterior cell position. One of the extracellular cues is provided by the F and U cells, which promote anterior fates. We show that the genes in the lin-3/let-23 signalling pathway required for hermaphrodite vulval induction also mediate this F/U signal. Reduction-of-function mutations in lin-3, let-23, sem-5, let-60 or lin-45 disrupt the fate of anterior cells. Likewise, activation of the pathway with ubiquitously produced signal results in posterior cells inappropriately adopting the anterior fates even in the absence of F and U. We have further used this genetic pathway to begin to understand how multiple positional cues are integrated to specify cell fate. We demonstrate that lin-15 acts in spicule development as it does in vulval induction, as a negative regulator of let-23 receptor activity. A second extracellular cue, from Y.p, also acts antagonistically to the lin-3/let-23 pathway. However, this signal is apparently integrated into the lin-3/let-23 pathway at some step after lin-45 raf and is thus functionally distinct from lin-15. We have also investigated the role of lin-12 in forming the anterior/posterior pattern of fates. A lin-12 gain-of-function defect is masked by redundant positional information from F and U.
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6

Ruvkun, Gary, Bruce Wightman, Thomas Bürglin und Prema Arasu. „Dominant gain-of-function mutations that lead to misregulation of the C. elegans heterochronic gene lin-14, and the evolutionary implications of dominant mutations in pattern-formation genes“. Development 113, Supplement_1 (01.01.1991): 47–54. http://dx.doi.org/10.1242/dev.113.supplement_1.47.

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The heterochronic gene lin-14 controls the temporal sequence of developmental events in the C. elegans postembryonic cell lineage. It encodes a nuclear protein that is normally present in most somatic cells of late embryos and LI larvae but not in later larval stages or adults. Two lin-14 gain-of-function mutations cause an inappropriately high level of the lin-14 nuclear protein late in development. These mutations delete 3′ untranslated sequences from the lin-14 mRNAs and identify a negative regulatory element that controls the formation of the lin-14 protein temporal gradient. The 21 kb lin-14 gene contains 13 exons that are differentially spliced to generate two lin-14 protein products with variable N-terminal regions and a constant C-terminal region. No protein sequence similarity to any proteins in various databases was found. The temporal and cellular expression patterns of lin-14 protein accumulation is altered by mutations in the heterochronic genes lin-4 and lin-28. The lin-4 gene is required to down-regulate lin-14 protein levels during the mid-Ll stage. The lin-4 gene product could be the trans-acting factor that binds to the negative regulatory element in the lin-14 3′ untranslated region. In contrast, the lin-28 gene activity positively regulates lin-14 protein levels during early LI. Thus, these genes act antagonistically to regulate the lin-14 temporal switch. The normal down-regulation of lin-14 within 10 h of hatching is not determined by the passage of time per se, but rather is triggered when feeding induces postembryonic development. Loss of lin-28 gene activity causes precocious down-regulation of lin-14 protein levels before feeding, whereas loss of lin-4 gene activity does not affect the level of lin-14 protein before feeding. These data suggest that to trigger the lin-14 temporal switch, the lin-4 gene is up-regulated after feeding which in turn down-regulates lin-14 via its 3′ untranslated region. We speculate on the evolutionary implications of dominant mutations in pattern-formation genes.
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7

Sommer, R. J., A. Eizinger, K. Z. Lee, B. Jungblut, A. Bubeck und I. Schlak. „The Pristionchus HOX gene Ppa-lin-39 inhibits programmed cell death to specify the vulva equivalence group and is not required during vulval induction“. Development 125, Nr. 19 (01.10.1998): 3865–73. http://dx.doi.org/10.1242/dev.125.19.3865.

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In the two nematode species Caenorhabditis elegans and Pristionchus pacificus the vulva equivalence group in the central body region is specified by the Hox gene lin-39. C. elegans lin-39 mutants are vulvaless and the vulval precursor cells fuse with the surrounding hypodermis, whereas in P. pacificus lin-39 mutants the vulval precursor cells die by apoptosis. Mechanistically, LIN-39 might inhibit non-vulval fate (cell fusion in C. elegans, apoptosis in P. pacificus), promote vulval fate or do both. To study the mechanism of lin-39 function, we isolated P. pacificus cell death mutants and identified mutations in ced-3. Surprisingly, P. pacificus ced-3; lin-39 double mutants form a functional vulva in the absence of LIN-39 activity. Thus, in P. pacificus lin-39 specifies the vulva equivalence group by inhibiting programmed cell death. Furthermore, these data reveal an important difference in a later function of lin-39 between the two species. In C. elegans, LIN-39 specifies vulval cell fates in response to inductive RAS signaling, and in P. pacificus LIN-39 is not required for vulval induction. Thus, the comparative analysis indicates that lin-39 has distinct functions in both species although the gene is acting in a homologous developmental system.
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8

Saito, Morihiro, Shinya Yamada, Taro Ishikawa, Hiromi Otsuka, Kimihiko Ito und Yoshimi Kubo. „Factors influencing fast ion transport in glyme-based electrolytes for rechargeable lithium–air batteries“. RSC Adv. 7, Nr. 77 (2017): 49031–40. http://dx.doi.org/10.1039/c7ra07501d.

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To elucidate the factors affecting Li-ion transport in glyme-based electrolytes, six kinds of 1.0 M tetraglyme (G4) electrolytes were prepared containing a Li salt (LiSO3CF3, LiN(SO2CF3)2, or LiN(SO2F)2) or different concentrations (0.5, 2.0, or 2.7 M) of LiN(SO2CF3)2.
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9

Fujisaki, Tomoaki, Marc G. Berger, Stefan Rose-John und Connie J. Eaves. „Rapid Differentiation of a Rare Subset of Adult Human Lin−CD34−CD38− Cells Stimulated by Multiple Growth Factors In Vitro“. Blood 94, Nr. 6 (15.09.1999): 1926–32. http://dx.doi.org/10.1182/blood.v94.6.1926.

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Abstract Recently, several reports of lineage-negative (lin−) CD34− cells with in vivo hematopoietic activity have focused interest on the properties and growth factor response characteristics of these cells. We have now identified a combination of 5 growth factors that are necessary and sufficient to stimulate a marked mitogenic and differentiation response by a subset of human lin−CD34−CD38− cells present in normal adult human marrow and granulocyte colony-stimulating factor (G-CSF)–mobilized blood. Less than 0.1% of the cells in highly purified (including doubly sorted) lin−CD34−CD38− cells from these 2 sources formed colonies directly in semisolid medium or generated such cells after 6 weeks in long-term culture. Nevertheless, approximately 1% of the same lin−CD34−CD38− cells were able to proliferate rapidly in serum-free liquid suspension cultures containing human flt-3 ligand, Steel factor, thrombopoietin, interleukin-3 (IL-3), and hyper–IL-6 to produce a net 28- ± 8-fold increase in total cells within 10 days. Of the cells present in these 10-day cultures, 5% ± 2% were CD34+ and 2.5% ± 0.9% were erythroid, granulopoietic, megakaryocytopoietic, or multilineage colony-forming cells (CFC) (13 ± 7 CFC per lin−CD34−CD38− pre-CFC). In contrast to lin−CD34+CD38−cells, this response of lin−CD34−CD38− cells required exposure to all of the 5 growth factors used. Up to 1.7 × 105 lin−CD34− adult marrow cells failed to engraft sublethally irradiated NOD/SCID-β2M−/− mice. These studies demonstrate unique properties of a rare subset of lin−CD34−CD38− cells present in both adult human marrow and mobilized blood samples that allow their rapid proliferation and differentiation in vitro within an overall period of 3 to 4 weeks. The rapidity of this response challenges current concepts about the normal duration and coordinated control of these processes in adults.
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10

Fujisaki, Tomoaki, Marc G. Berger, Stefan Rose-John und Connie J. Eaves. „Rapid Differentiation of a Rare Subset of Adult Human Lin−CD34−CD38− Cells Stimulated by Multiple Growth Factors In Vitro“. Blood 94, Nr. 6 (15.09.1999): 1926–32. http://dx.doi.org/10.1182/blood.v94.6.1926.418k14_1926_1932.

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Recently, several reports of lineage-negative (lin−) CD34− cells with in vivo hematopoietic activity have focused interest on the properties and growth factor response characteristics of these cells. We have now identified a combination of 5 growth factors that are necessary and sufficient to stimulate a marked mitogenic and differentiation response by a subset of human lin−CD34−CD38− cells present in normal adult human marrow and granulocyte colony-stimulating factor (G-CSF)–mobilized blood. Less than 0.1% of the cells in highly purified (including doubly sorted) lin−CD34−CD38− cells from these 2 sources formed colonies directly in semisolid medium or generated such cells after 6 weeks in long-term culture. Nevertheless, approximately 1% of the same lin−CD34−CD38− cells were able to proliferate rapidly in serum-free liquid suspension cultures containing human flt-3 ligand, Steel factor, thrombopoietin, interleukin-3 (IL-3), and hyper–IL-6 to produce a net 28- ± 8-fold increase in total cells within 10 days. Of the cells present in these 10-day cultures, 5% ± 2% were CD34+ and 2.5% ± 0.9% were erythroid, granulopoietic, megakaryocytopoietic, or multilineage colony-forming cells (CFC) (13 ± 7 CFC per lin−CD34−CD38− pre-CFC). In contrast to lin−CD34+CD38−cells, this response of lin−CD34−CD38− cells required exposure to all of the 5 growth factors used. Up to 1.7 × 105 lin−CD34− adult marrow cells failed to engraft sublethally irradiated NOD/SCID-β2M−/− mice. These studies demonstrate unique properties of a rare subset of lin−CD34−CD38− cells present in both adult human marrow and mobilized blood samples that allow their rapid proliferation and differentiation in vitro within an overall period of 3 to 4 weeks. The rapidity of this response challenges current concepts about the normal duration and coordinated control of these processes in adults.
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Dissertationen zum Thema "Lin-3"

1

Kroll, Jochen. „A Casson-Lin invariant for knots in homology 3-spheres“. [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=967833590.

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2

Yang, Wen. „Some new results on the SU(3) Toda system and Lin-Ni problem“. Thesis, University of British Columbia, 2015. http://hdl.handle.net/2429/54075.

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In this thesis, we mainly consider two problems. First, we study the SU(3) Toda system. Let (M,g) be a compact Riemann surface with volume 1, h₁ and h₂ be a C¹ positive function on M and p1; p2 ∈ ℝ⁺. The SU(3) Toda system is the following one on the compact surface M [Formula and equation omitted] where ∆ is the Beltrami-Laplace operator, αq ≥ 0 for every q ∈ S₁, S₁ ⊂ M, Bq ≥ 0 for every q ∈ S₂,S₂ ⊂ M and q is the Dirac measure at q ∈ M. We initiate the program for computing the Leray-Schauder topological degree of SU(3) Toda system and succeed in obtaining the degree formula for p1 ∈ (0,4π)(4π,8π), p2 ∉ 4πℕ when S₁ = S₂ = 0. Second, we consider the following nonlinear elliptic Neumann problem {∆u-μu +uq =0 in Ω,u > 0 in Ω,au/av=0 on aΩ. where q=n+2/n-2, μ > 0 and Ω is a smooth and bounded domain in ℝn. Lin and Ni (1986) conjectured that for μ small, all solutions are constants. In the second part of this thesis, we will show that this conjecture is false for a general domain in n = 4, 6 by constructing a nonconstant solution.
Science, Faculty of
Mathematics, Department of
Graduate
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3

Vargas, Velazquez Amhed Missael. „Evolution de l'induction vulvaire chez C. elegans et des autres nematodes“. Electronic Thesis or Diss., Paris Sciences et Lettres (ComUE), 2018. http://www.theses.fr/2018PSLEE075.

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Caenorhabditis elegans est un organisme modèle couramment utilisé pour étudier les processus de développement tels que la formation de la vulve. Ce processus repose sur l'induction précise des cellules qui donnent naissance à la vulve. Les destins cellulaires résultants sont organisés en un motif caractéristique, qui est conservé tout au long du Caenorhabditis et des nématodes rhabditides. En contraste avec cette conservation des cellules vulvaires, ma thèse présente deux axes d'étude qui ont révélé des signatures d'évolution des voies de développement contrôlant l'induction vulvaire. Dans le premier, je présente un changement des motifs cis-régulateurs nécessaires à l'expression cellulaire spécifique de lin-3 (EGF), un gène codant pour la molécule de signalisation qui induit le destin des cellules de la vulve. Les trois sites de liaison aux facteurs de transcription requis pour l'expression de lin-3 chez C. elegans ne sont observés que chez les espèces du groupe Elegans. En utilisant des techniques de FISH à molécule unique et d'édition de génome, je montre que le remplacement des sites endogènes de C. elegans par un fragment de 58 pb contenant un seul site (provenant de C. angaria) produit des niveaux d'ARNm de type sauvage de type lin-3. Je conclus que l'évolution compensatoire pour l'exigence de sites de liaison de C. elegans s'est produite en cis. Dans la deuxième partie de mon étude, j'ai utilisé une approche de cartographie par séquençage et une collection de mutants de la vulve chez Oscheius tipulae, voisin de C. elegans dans le clade rhabditid, afin d'identifier les mutations dans les gènes agissant sur la spécification du modèle de destin des cellules de la vulve. La seule mutation collectée pour rendre les animaux sans vulve correspond à une délétion de la région cis-régulatrice contrôlant l'expression de O. tipulae lin-3, ce que j'ai confirmé par l'édition du génome de CRISPR / Cas9. Les mutants présentant un excès d'induction de la vulve portent des lésions moléculaires dans la voie plexin / semaphorin, un système de signalisation cellulaire qui, selon moi, agit dans le positionnement antéropostérieur des cellules donnant lieu à la vulve par analyse microscopique. Enfin, d’autres animaux d’O. tipulae dont le destin de cellules vulvaires est perturbé présentent des mutations dans des composants de la voie Wnt; pour cette raison, j'ai étudié les profils d'expression des ligands Wnt d'O. tipulae et révélé leur conservation avec C. elegans. Ces deux études mettent en évidence le processus de dérèglement du système de développement (DSD) en tant que processus évolutif qui se produit lors de la formation de la vulve sur des nématodes rhabditides
Caenorhabditis elegans is a model organism commonly used to study developmental processes such as vulva formation. This process relies on the precise fate induction of the cells that give rise to the vulva. The resultant cellular fates are arranged into a characteristic pattern, which is conserved across the vulva development of Caenorhabditis and rhabditid nematodes. In contrast to this extensive conservation of the vulval cell fate pattern, my thesis presents two lines of study that revealed signatures of evolution in developmental pathways controlling vulval induction. In the first one, I present a turnover of cis-regulatory motifs required for the cell-specific expression of lin- 3 (EGF), a gene coding for the signalling molecule which induces vulva cell fates. The three transcription factor binding sites required for lin-3 expression in C. elegans are observed only in species of the Elegans group. Using single-molecule FISH and genome editing techniques, I show that the replacement of the endogenous C. elegans binding sites by a 58 bp fragment containing a single site (coming from C. angaria), produces wild-type mRNA levels of lin-3. I conclude that compensatory evolution for the requirement of C. elegans binding sites occurred in cis. In the second line of study, I used a mapping-bysequencing approach and a collection of vulva mutants in Oscheius tipulae, a neighbour of C. elegans in the rhabditid clade, to identify mutations in genes acting on vulva cell fate pattern specification. The only collected mutation to render animals vulvaless corresponds to a deletion of the cis-regulatory region controlling the expression of O. tipulae lin-3, which I confirmed by CRISPR/Cas9 genome editing. Mutants with an excess of vulva induction carry molecular lesions in the plexin/semaphorin pathway, a cell signalling system which I show to act in the antero-posterior positioning of the cells giving rise to the vulva by microscopic analysis. Finally, other O. tipulae animals with disrupted vulval cell fate pattern hold mutations in components of the Wnt pathway; for this reason, I investigated the expression profiles of Wnt ligands of O. tipulae and revealed their conservation with C. elegans. Both of these studies highlight the process of Developmental System Drift (DSD) as an evolutionary process occurring on vulva formation of rhabditid nematodes
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4

Lazouk, Melha-Amel. „Étude de l’impact de l’environnement sur les productions et des procédés sur la qualité des produits : application à la graine de lin“. Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2188.

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Connues pour leur forte teneur en huile, oméga 3, antioxydants et fibres, les graines de lin sont de plus en plus demandées par les industries. D’où l’importance de contrôler leurs productions. Le but de ce travail est d’étudier l’effet des paramètres environnementaux et de la variété sur la composition de la graine de lin et sur le procédé ultérieur de pressage. Pour cela dix variétés de lin oléagineux ont été cultivées sur deux sites différents (Picardie et centre de la France) au cours des années 2011, 2012 et 2013. L’étude a révélé un fort effet variétal sur les teneurs en huile, C18:3, amidon et le PMG tandis que le lieu de culture n’a affecté que la teneur en lipides et amidon. L’effet année a quant à lui été marqué pour le PMG, les teneurs en protéines, lipides et C18:3. Le pressage des graines précédemment caractérisées a montré une forte corrélation entre teneur protéines et rendement. Afin d’améliorer le processus d'expression, le dépelliculage des graines de lin avant le pressage a été envisagé. Ainsi, l’étude du pressage des graines de lin sur presse hydraulique et presses continue montre la possibilité du pressage des graines dépelliculées. Une concordance entre les performances de pressage à l’échelle laboratoire et à l’échelle pilote a été obtenue pour les graines entières et dépelliculées ce qui laisse présager une transposition possible vers l’échelle industrielle
Flaxseed is known for their high oil content, omega 3, antioxidants and fiber. To meet growing demand, this requires controlling their production. The aim of this work is to study the effect of environmental factors and cultivar on linseed composition and subsequent pressing process. Ten linseed cultivars were grown in two different locations (north and south of France) during years 2011, 2012 and 2013. Every year have been characterized in terms of pluviometry, sunshine hours and degree days, each climatic factor has been cumulated from flowering to harvest. A strong impact of cultivar on oil, C18:3 and starch content has been noticed whereas the growing location has only affected the starch and lipid contents. Year effect has been recorded on thousand kernel weight, proteins, oil, C18:3 and starch content. Oil expression using the seeds previously characterized has exhibited a strong correlation between protein content and oil yield. To improve the pressing process, dehulling flax seeds before pressing was considered. The study of the pressing flax seeds on hydraulic and continuous press shows the possibility of pressing the dehulling flaxseeds. The concordance between the pressing performance at the laboratory scale and pilot scale was highlighted for the whole and dehulled seeds. This could be suggests a possible transposition to the industrial scale
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5

Johnson, Ryan William. „Genetic Regulation of Caenorhabditis Elegans Post-Embryonic Development Involving the Transcription Factors EGL-38, VAB-3, and LIN-14“. The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1213060175.

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6

Saffer, Adam M. „The C. elegans class A synthetic multivulva genes inhibit ectopic RAS-mediated vulval development by tightly restricting expression of lin-3 EGF“. Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/62619.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 2011.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (p. 236-259).
The class A and B synthetic multivulva (synMuv) genes of C. elegans redundantly antagonize an EGF/Ras pathway to prevent ectopic vulval induction. The class B synMuv genes encode many proteins known to remodel chromatin and repress transcription. The class A synMuv genes likely also function in transcription, although their specific molecular functions are unknown. We have identified a class A synMuv mutation in the promoter of lin-3 EGF, revealing that lin-3 is the key biological target of the class A synMuv genes in vulval development. Using FISH with single mRNA molecule resolution, we found that class AB synMuv double mutants exhibit widespread ectopic lin-3 expression. Our results show that lin-3 EGF is normally expressed in the germline, and many class B synMuv genes have previously been implicated in inhibiting germline fates in somatic cells. We propose that the class A synMuv genes specifically repress ectopic lin-3 EGF expression through a site in the lin-3 promoter and the class B synMuv genes either directly or indirectly repress lin-3 as a consequence of their role in regulating the germline/soma distinction. The class A and B synMuv genes had previously been thought of as two parallel pathways, but we have found that each of those pathways is actually composed of multiple parallel pathways. While class AB synMuv double mutants have a strong Muv phenotype, most class AA synMuv double mutants exhibit a weak Muv phenotype, and most pairs of class B synMuv mutants can enhance each other in sensitized backgrounds, indicating that most genes within a class can function in parallel. We also found that some pairs of synMuv genes cannot act in parallel, indicating that they function together to repress ectopic lin-3 expression. We also report the molecular characterization of the class A synMuv gene lin-38 and the identification of mcd-1 as a class A synMuv gene. lin-38 and mcd-1 encode paralogous zinc-finger proteins. Unlike previously studied class A synMuv genes that function specifically in vulval development by repressing lin-3, both lin-38 and mcd-1 control multiple aspects of development by regulating target genes other than lin-3.
by Adam M. Saffer.
Ph.D.
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Fahs, Zeinab. „Isolement de gènes exprimés dans la graine de lin et potentiellement impliqués dans l'accumulation d'acides gras polyinsaturés et inhabituels : caractérisation de la fonctionnalité in vivo et in vitro des enzymes correspondantes“. Thesis, Compiègne, 2016. http://www.theses.fr/2016COMP2275.

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L'huile de lin est considérée comme une des plus riches en acide linolénique (oméga- 3), avec certaines variétés de lin oléagineux produisant jusqu'à 65% d'acide a-linolénique. Cette huile utilisée depuis longtemps en industrie chimique pour la confection de peintures, vernis, agents tensioactifs, présente aussi des bénéfices pour la santé humaine avec un apport journalier d'environ 2 g.f 1 (diminution de la pression artérielle, prévention de thrombose...). Il parait donc raisonnable aujourd'hui d'augmenter la production de l'huile de lin riche en oméga-3 pour répondre à ces différents besoins. La sélection de cultivars producteurs d'huile de la qualité demandée devient impérative. Pour cela, des connaissances sur les mécanismes de synthèse et d'accumulation AG polyinsaturés (PUFA) dans les graines de lin sont à acquérir. Dans ce contexte, nous avons évalué le rôle des enzymes de type LPAAT dans l'accumulation des PUFA dans le but de sélectionner des isoformes compétitives dans leur accumulation au niveau des TAG. Les gènes Lpaat ont été isolés à partir des graines de lin âgées de 20 JAF, phase active de remplissage en huile. La fonctionnalité des protéines correspondantes a été testée par complémentation dans une souche JC201 d’E. coli déficiente en activité LPAAT. Une caractérisation de ces enzymes a été effectuée par des tests in vitro et in vivo. Les résultats ont montré la présence d'une isoforme, nommée LPAAT2A, dont l'activité LPAAT présente une spécificité et sélectivité élevées vis-à-vis des PUFA. Dans un 2ème temps, nous avons mesuré in vitro et in vivo le potentiel des enzymes LPAAT provenant de litchi et de lin vis-à-vis des AG de type cyclopropanique. Ces AG possèdent des propriétés physico-chimiques intéressantes pour l'industrie des lubrifiants et des cosmétiques et sont produits par une enzyme spécifique « la CFA synthase ». Nous avons généré des lignées d'Arabidopsis exprimant la CFA synthase d’E.coli puis co-exprimé le gène Lpaat de litchi. Une augmentation de la teneur en AGC (AG cycliques) dans les lignées transgéniques obtenues reflète la spécificité de la LPAAT de litchi vis-à-vis des AGC. Nous nous sommes aussi intéressés aux enzymes de types sPLA2a (phospholipase A2). L'isolement du gène correspondant a été effectué à partir des graines de lin pendant la phase active de remplissage en huile. La caractérisation de son activité a été effectuée par des tests in vitro et in vivo. Les résultats ont montré que l'expression du gène sP/a2a de lin dans les graines d' Arabidopsis provoque une augmentation du poids de la graine ainsi qu'une augmentation du contenu en acide linolénique dans les TAG. L'ensemble de ces résultats montre l'existence d'un système enzymatique endogène chez le lin efficace vis-à­vis des PUFA et qui semble stimuler le métabolisme lipidique une fois exprimé chez Arabidopsis
Flaxseed oil contain high amount of oméga-3 and present different industrials applications and human health benefits. ln this work, we aimed to identify enzymes allowing the accumulation of high level of omega-3 in linseed plants. ln this context, we evaluated the role of Lysophophatidic acid acyltransferases (LPAAT) and Phospholipases A2 (PLA2) enzymes in the accumulation of omega-3 by in vitro and in vivo approaches. Results showed the presence of a LPAAT2A isoform into flax genome having a high specificity and selectivity toward omega-3. Expression of Lpaat2A and sPia2a gene in Arabidopsis seeds increase seed weight, oil production and omega-3 content (up to 10% and 11%) in transformant seeds respectively. These results showed the presence in linseed plant of an efficient enzymatic system toward omega-3 accumulation. Furthermore, we have evaluated in vitro and in vivo the potential of Litchi and flax LPAAT enzymes toward the production of cyclopropane fatty acids (CFA). These fatty acids are naturally produced by a specific enzyme «CFA synthase» with physico-chemical properties interesting to lubricant and cosmetics industries. ln this context, we have generated Arabidopsis lines expressing E. coli Cfa synthase with or not co-expression of litchi Lpaat gene. Result showed an increase of 25% in the content of CFA in transgenic line co-expressing Cfa synthase and litchi Lpaat comparing to the transgenic lines expressing the CFA synthase. This increase in the level of CFA in transgenic seeds reflects the specificity of Litchi LPAAT toward CFA
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Alessio, Sara <1990&gt. „Reading Brexit through BrexLit: fictional responses to political crisis“. Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amsdottorato.unibo.it/9427/3/Alessio_Sara_tesi.pdf.

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Reading Brexit through BrexLit is a dissertation centred on the 2016 referendum on British exit from the European Union and on Brexit Literature (‘BrexLit’). The thesis focuses on the relation between Englishness and the Leave vote, analysing themes and images at the core of the Brexit campaign in parallel with selected literary works published both before and after the political outcome, and on the impact of the referendum on literature itself. After an introduction that serves as a framework, the work is divided into three different sections. The first one is dedicated to an analysis of Brexit from a political point of view, outlining global tendencies and British peculiarities that influenced the vote and explaining Brexit as an English (more than British) phenomenon. The second section moves from the political aspects of the study to the literary ones, showing that Brexit themes are to be found in contemporary fictions published before the referendum and focusing on two novels that are particularly concerned both with the structures of feeling at the core of the campaign and with English identity: Speak for England (2005) by James Hawes and The White Family (2002) by Maggie Gee. The third and last section introduces the reader to Brexit Literature (‘BrexLit), which is a new sub-genre that has flourished from the referendum onwards. The section looks at the main characteristics of the sub-genre, distinguishing between two main categories of BrexLit fictions: political and intimate novels. This sections ends with the close reading of two BrexLit novels published in 2018, Perfidious Albion by Sam Byers and Middle England by Jonathan Coe, which are the most representative in relation to the two categories mentioned above and in the way they engage, as the novels of the previous section, with the structures of feeling exploited in Brexit discourse.
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Serio, Marco. „Stefan George e Friedrich Hoelderlin: due ciclicità a confronto“. Doctoral thesis, University of Trento, 2016. http://eprints-phd.biblio.unitn.it/1841/3/DissertazionE_Finale.pdf.

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Lo studio affronta il problematico argomento della ciclicità in relazione a due grandi lirici tedeschi, Stefan George e Friedrich Hoelderlin, misurandosi con una vasta tradizione critica e con non agevoli dettati ermeneutici. Il lavoro è scandito in sette capitoli, dei quali il primo analizza il termine 'ciclo', partendo dal suo significato etimologico di cerchio, circolo e ruota, per poi soffermarsi sul significato di successione di eventi memorabili all'interno di un'epoca. Il ciclo è inteso quale categoria estetico-semantica che, incardinata nella dimensione riflessiva del linguaggio, permette di leggere le liriche sia come singoli testi autonomi sia come testi poetici inseriti in un insieme più vasto. Nel secondo capitolo si analizza la nozione di rituale ciclico in Stefan George nel contesto della Germania guglielmina, lacerata dalla frattura fra Bourgeoise e Bildungsbuergertum. Da questo prospettiva il rituale ciclico georgeano è concepito come mito che mira a creare una tradizione culturale funzionale ai bisogni della Germania, legittimandone i caratteri di specificità, eccellenza ed esclusività rispetto alle altre nazioni, nonché esorcizzando lo stereotipo tedesco di "verspaetete Nation", condannata a restare in uno stato di frammentazione territoriale fino al 1871. Il mito carente, capace di tradurre in realtà una volontà di potenza di stampo nietzscheano, viene incarnato dal poeta come esponente di una realtà potenziata che si colloca in un punto di scissura tra finito e infinito. Fondandosi sulla ripetizione di un'azione, il rituale estetico garantisce stabilità e continuità e offre un efficace antidoto contro la fugacità del tempo, mentre l'espressione poetica diviene una totalità in sé conchiusa. In Stefan George il culto della bellezza genera un cerchio magico, nel quale egli si trasforma da esteta in vate che preconizza la palingenesi dell'umanità. Oggetto di indagine sono state, a titolo di esempio, le strutture cicliche di Der Teppich des Lebens und die Lieder von Traum und Tod mit einem Vorspiel. Infine il lavoro volge a contemplare il rapporto tra Friedrich Hoelderlin e Stefan George, a partire dall'analisi del contributo di George e dei suoi sodali per la riscoperta dell'opera tarda di Hoelderlin per poi estendersi alle fonti utilizzate nel processo ermeneutico della poesia georgeana, nonché alle analogie tematiche rintracciabili tra i due poeti tedeschi che mantengono inalterata la propria singolarità sul piano stilistico e linguistico. Ciò avviene attraverso l'analisi di testi esemplari come gli hoelderliniani Fragment philosophischer Briefe e Verfahrungsweise des poetischen Geistes oltre agli inni Patmos, Friedensfeier, Brot und Wein e Der Zeitgeist e le loro ricadute entro l'opera georgeana, a fronte dello specifico paradigma della ciclicità.
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De, Roia Giulia <1993&gt. „"Il bilinguismo precoce: i vantaggi di un'educazione bilingue a partire dall'asilo nido per la fascia 0-3 anni"“. Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/18617.

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La presente tesi si occuperà di indagare il bilinguismo, precisamente nella fascia d’età comprensiva 0-3 anni, e di dimostrarne i vantaggi, eliminando in questo modo l’ombra dei vari pregiudizi che hanno spesso circondato questo tema. In particolare, grazie ad un’analisi degli aspetti neurologici e biologici riguardanti sia il cervello infantile ed il suo sviluppo, sia i processi d’acquisizione (monolingue/bilingue) delle lingue del bambino, verranno evidenziati quei fattori fondamentali e le corrispettive variabili che rendono possibile, e spesso in modo più spontaneo e naturale, un’acquisizione bilingue precoce. Poste le premesse a livello neurologico e biologico, di conseguenza a quanto analizzato, successivamente la tesi si sposterà su un piano prettamente pratico, riguardante la dimensione educativa che sottostà al successo di un’acquisizione bilingue. Verrà posta l’attenzione principalmente sulla realtà dell’asilo nido, una struttura che svolge il compito fondamentale di offrire al bambino un adeguato programma di educazione bilingue, come di garantire una stimolazione ed un supporto sufficiente a raggiunge questo fine. Alla luce di ciò, il presente elaborato indagherà ed analizzerà le migliori caratteristiche e modalità che rendono tale un ottimo programma bilingue, soffermandosi singolarmente sul ruolo dell’educatore/insegnante, l’ambiente in cui il bambino è immerso, e le varie attività a cui egli viene sottoposto.
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Bücher zum Thema "Lin-3"

1

Arts), Lin Hwai-min iInternational Dance Conference (2005 Taipei National University of. Lin Huaimin wu dao guo ji xue shu yan tao hui lun wen ji =: Lin Hwai-min International Dance Conference proceedings, 2005.8.2-3. Taibei Shi: Xing zheng yuan wen hua jian she wei yuan hui, 2005.

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Chen, Jintian. Lin shi Taiwan jiu guan diao cha hui di 1 bu diao cha di 3 hui bao gao shu: Taiwan si fa. Taizhong Shi: Taiwan Sheng wen xian wei yuan hui, 2000.

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Yang, Yun Fei Ou. Lie ying ji 3/3. China: Yunnanrenmin, 1999.

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Riyaz, Riyaz Muhammad. 3 Line selekshan. Faysalabad: Al-Sehat Islamik Mishan, o.D.

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Brunette, Louise, Georges L. Bastin, Isabelle Hemlin und Heather Clarke, Hrsg. The Critical Link 3. Amsterdam: John Benjamins Publishing Company, 2003. http://dx.doi.org/10.1075/btl.46.

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Touba, Jacquiline. Taiwan: Lisa Lin's painting "Making mooncakes". New York: PowerKids Press, 1997.

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Ou, Yang. Lie ying ji 2/3. [S.l.]: Yunnanrenmin, 1999.

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Bosch, M. Open line 3: Teacher's book. Madrid: Editorial Alhambra, S.A, 1989.

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Bosch, M. Open line 3: Students' workbook. Madrid: Editorial Alhambra, S.A, 1989.

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Ou, Yang. Lie ying ji 1/3. [S.l.]: Yunnanrenmin, 1999.

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Buchteile zum Thema "Lin-3"

1

Wee, Hoeteck. „Broadcast Encryption with Size $$N^{1/3}$$ and More from k-Lin“. In Advances in Cryptology – CRYPTO 2021, 155–78. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84259-8_6.

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Rausch, Mathias. „LIN (1)“. In Kommunikationssysteme im Automobil, 47–71. München, Germany: Carl Hanser Verlag GmbH & Co. KG, 2022. http://dx.doi.org/10.1007/978-3-446-47457-4_3.

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Rausch, Mathias. „LIN (2)“. In Kommunikationssysteme im Automobil, 179–98. München, Germany: Carl Hanser Verlag GmbH & Co. KG, 2022. http://dx.doi.org/10.1007/978-3-446-47457-4_7.

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Hermann, Marc. „Lin Shu“. In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_15034-1.

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Simons, Silke. „Lin Yutang“. In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_15036-1.

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Villars, P., K. Cenzual, J. Daams, R. Gladyshevskii, O. Shcherban, V. Dubenskyy, V. Kuprysyuk und I. Savysyuk. „LiN(SO2F)2“. In Structure Types. Part 9: Space Groups (148) R-3 - (141) I41/amd, 285–86. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-02702-4_192.

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Bährle-Rapp, Marina. „grain de lin“. In Springer Lexikon Kosmetik und Körperpflege, 233. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_4472.

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Balestrini, Nassim W. „Miranda, Lin-Manuel“. In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_12159-1.

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Gong, Junqing, Ji Luo und Hoeteck Wee. „Traitor Tracing with $$N^{1/3}$$-Size Ciphertexts and O(1)-Size Keys from k-Lin“. In Advances in Cryptology – EUROCRYPT 2023, 637–68. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-30620-4_21.

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von der Wense, H. C., und A. J. Pohlmeyer. „Building Automotive LIN Applications“. In Advanced Microsystems for Automotive Applications 2001, 279–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-18253-2_26.

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Konferenzberichte zum Thema "Lin-3"

1

Lin, Ray-Qing, und Joseph T. Klamo. „Ship Motions From Unsteady Maneuvering in Two-Dimensional Waves: Part I—Numerical Simulations“. In ASME 2011 30th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2011. http://dx.doi.org/10.1115/omae2011-49018.

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Numerically simulating the six-degrees-of-freedom response motions of a ship executing an unsteady maneuver in a two-dimensional wave environment is one of the most challenging tasks in seakeeping. Mathematical difficulties may occur for several reasons. For example, the rapid change in encounter frequencies may cause a numerical dynamics imbalance. Furthermore, in order to predict the ship’s track (ship heading) accurately, the rudder forces and two-dimensional drift forces must be predicted accurately; otherwise, erroneously predicted headings can ultimately lead to obtaining entirely different ship motions. To overcome these problems, we added a well-behaved, pre-conditional iterative method into the hybrid flow-based, fully-nonlinear ship motion model, DiSSEL (Digital, Self-consistent Ship Experimental Laboratory), in a two-dimensional wave environment. DiSSEL includes two components: a ship-wave interactions model (Lin et al., 2005[1], Lin and Kuang, 2006[2]), and a solid body motions interactions model (Lin and Kuang 2010[3]). The rudder and appendage forces (Lin et al, 2010[4]) are included in the solid body motions component. This refined model is able to overcome the mathematical dynamics imbalance when the encounter frequency rapidly changes as well as accurately calculate the forces on the hull and rudders. Finally the simulations of ship response motions at various relative headings and at various forward speeds in a two-dimensional seaway will be benchmarked against experimental model data for the test cases.
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Lin, Ray-Qing, und Joseph Klamo. „Ship Track Impacted by Incident Waves“. In ASME 2010 29th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/omae2010-20353.

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Correctly predicting the track of a ship when impacted by incident waves is one of the most important tasks in accurately simulating seakeeping performance. This is especially difficult during a storm surge in coastal regions, where the bottom topography rapidly changes. In fact accurately predicting a ship track in calm water has not been completely solved. Most recently, Lin et al. integrated the total forces and moments over an actual ship hull and rudders in a fully nonlinear ship motion model named the Digital, Self-consistent Ship Experimental Laboratory (DiSSEL) by using finite element/finite difference in calm water (Lin et al. 2005 [1], Lin and Kuang, 2006 [2], 2008 [3], 2009 [4]; Lin et al., 2009 [5]). The new method is not only accurate, but also computationally efficient. As part of a continuing effort, in this study, the incident wave impact is now included. The incident wave impact on the ship hull and rudders is integrated over the actual wetted surfaces at each time step, based on the ship position. First, the numerical simulations are benchmarked using existing experimental data for an experimental hull form. The DiSSEL simulations agree well with the experimental data. Based on the simulations, we explore the physics to gain an understanding into the possible factors that cause changes to the ship tracks. For example, why will the turning circle of a ship with constant rudder angle and ship speed, in the presence of waves, sometimes be a spiral while other times remain a circle? Finally DiSSEL will be coupled with the coastal wave model by Lin and Perrie (1997, 1999) [6], [7], to predict the ship track in a coastal region impacted by a storm surge. Future improvements to DiSSEL will include the incorporation of a propeller model. Since a model for the propellers has not yet been implemented, the influence of the propeller slipstream on the rudder is currently handled by empirically modifying the effective inflow velocity into the rudder to account for the acceleration of the flow by the propeller.
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Chee, J. K., H. W. Lee, H. Y. Jang, S. H. Lee und D. H. Shin. „Engineering of Compact Green Laser for Digital Video Disk Recorder“. In Optical Data Storage. Washington, D.C.: Optica Publishing Group, 1994. http://dx.doi.org/10.1364/ods.1994.mb2a.

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Most optical data storage systems require compact, continuous-wave laser sources. The desirable features include the maintenance-free operations for the low noise(< −100 dB LIN), small output power drift(< ±3%) within the device life cycle(> 10,000 hours), wide range of operating temperature(10 ~ 35°C) and sufficient output power(> 20 mW). These requirements are easily satisfied with the near infrared semiconductor laser sources that are presently used in the database and audio/video systems.
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Lin, Jian, und Robert G. Parker. „Natural Frequency Veering Patterns of Planetary Gears Under Design Parameter Variation“. In ASME 2000 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/detc2000/ptg-14438.

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Abstract Noise and vibration reduction is a critical concern in planetary gear applications. During the design process, system parameters are varied to evaluate alternative design choices, avoid resonances, optimize load distribution, and reduce weight. It is important to characterize the effects of parameter variations on the natural frequencies and vibration modes for effective vibration tuning. In planetary gear dynamic models (Figure 1), the key design parameters include the mesh stiffness, support/bearing stiffness, component mass, and moment of inertia. Some plots of natural frequencies versus planetary gear parameters are presented by Cunliffe et al. (1974), Botman (1976), Kahraman (1994), and Saada and Velex (1995). Lin and Parker (1999a) analytically characterized the unique, highly-structured properties of planetary gear natural frequency spectra and vibration modes. They also derived simple, closed-form expressions for the sensitivities of natural frequencies and vibration modes to these parameters (Lin and Parker, 1999b). The natural frequency plots in the above literature show natural frequency veering phenomena where two eigenvalue loci approach each other as a parameter is varied but then abruptly veer away like two similar charges repelling (Figure 2a). The phenomenon has been extensively studied (Leissa, 1974; Perkins and Mote, 1986; Pierre, 1988; Chen and Ginsberg, 1992; Happawana et al., 1998). The vibration modes of the veering eigenvalues are strongly coupled and undergo dramatic changes in the veering neighborhood. Eigenvalue veering is also related to mode localization that can occur when disorder is introduced into nominally symmetric systems like turbine blades, space antennae, multi-span beams and other structures (Pierre, 1988). In the case of especially sharp veering, it is sometimes difficult to distinguish between intersection and veering just by observing eigenvalue plots. Curve veering/crossing complexity obstructs the tracing of eigenvalue loci under parameter changes. Also, when multiple curves veer or intersect close together (Figure 3), strong modal coupling (and associated operating condition response changes) occurs that is not identifiable from frequency loci plots. The objective of this work is to analytically characterize the rules of eigenvalue veering in planetary gear vibration. The special veering patterns derived here help to trace natural frequencies and examine impacts of design parameters on vibration. These veering patterns, combined with the unique modal properties (Lin and Parker, 1999a) and the eigensensitivies analysis (Lin and Parker, 1999b), provide designers considerable insight into planetary gear free vibration.
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Hu, L., und G. Chen. „Thermal Radiative Heat Transfer Between Closely Spaced Nanostructures“. In ASME 4th Integrated Nanosystems Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/nano2005-87066.

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Thermal emission control with nanostructures has attracted considerable attention because of its potential applications in thermophotovoltaic (TPV) devices [1–3]. The optical-to-electrical conversion in a TPV system is driven by photons with energy higher than the electronic bandgap of the photovoltaic cell. A narrow-band emitter with emission spectrum slightly above the bandgap is ideal, which maximizes the conversion efficiency as well as minimizes the waste heat that deteriorates the performance of the cell. Specially designed nanostructures alters the band structure of photons in much the same way as the crystal lattice does on electrons inside semiconductors, thus changing the thermal emission spectrum. By employing nanostructure-enabled emission control, Lin, et al, projected an efficiency of 34% for TPV systems [2].
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Qiu, Ruifeng, und Fengchun Lei. „On the Heegaard Genera of 3-manifolds Containing Non-separating Surfaces“. In Proceedings of the Nankai International Conference in Memory of Xiao-Song Lin. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812819116_0015.

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7

Heimiilitinen, Raimo P., und Eero Kettunen. „On-line Group Decision Support by HIPRE 3+ and Group Link“. In The International Symposium on the Analytic Hierarchy Process. Creative Decisions Foundation, 1994. http://dx.doi.org/10.13033/isahp.y1994.035.

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Lin, Ray-Qing, Susan Brewton, George S. Hazen und Damien Bretall. „Numerical Modeling of a Planing Hull Maneuvering in Full Scale Trail“. In SNAME 13th International Conference on Fast Sea Transportation. SNAME, 2015. http://dx.doi.org/10.5957/fast-2015-010.

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The high-speed Rigid Hulled Inflatable Boat (RHIB) is one of the key forms of transportation for the U.S. Navy in littoral regions. This planing craft, shown in Figure 1, is a lightweight, high-performance, high-capacity boat. It is constructed with a solid, shaped hull and flexible tubes at the gunwale. The flexible tubes maintain a high buoyancy to avoid capsize in bad seas and to better absorb heavy loads. When the RHIB maneuvers in a seas state greater than 2, however, it often gets off plane or jumps to an entirely different heading regardless of the craft speed and heading relative to the direction of wave propagation. This behavior may cause the planing boat to miss its target track and veer off course. Furthermore, if a RHIB is supporting shore facilities or large ships transporting troops, the deviations and jumps may also impact the safety of the troops. In order to shine a light on improving the RHIB planing craft design for better performance at higher sea states, this study used a fully-nonlinear ship motion model named the Digital Self consistent Ship Experimental Laboratory (DiSSEL) by Lin and Kuang (2011a and 2011b) as a numerical tool to examine the dynamic balance of a six-degree-freedom (6DOF) RHIB. First the RHIB is maneuvered in Seas State 2, then in Seas State 3. The results of the simulation serve to better understand the underlying physics that cause dynamics instability at higher sea states. This study also serves to validate the accuracy of the DiSSEL ship motion model with observational data of a 10-meter long RHIB at Seas State 2. The model shows good agreement with experimental data in all headings and with a wide range of boat speeds (up to Froude number of 1.265).
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Dai, Xinxin, Baoliang Zhao, Yucheng He, Yu Sun und Ying Hu. „A Foot-Controlled Interface for Endoscope Holder in Functional Endoscopic Sinus Surgery“. In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3421.

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Endoscopic nasal surgery is with minimal invasiveness for the surgical treatment of nasal disease. During traditional functional endoscopic sinus surgery (FESS), the surgeon uses one hand to hold the surgical instrument leaving the other hand to hold the endoscope. When the surgeon needs to use two hands to perform some complex procedure, an assistant surgeon is required to help holding the endoscope, and this requires good teamwork and long-time training. To solve this problem, researchers proposed to use robots to hold the endoscope, freeing the surgeon’s hands for bimanual operation. Sun developed a passive arm with pneumatic locking mechanism to hold the endoscope in FESS, but the surgeon needs to adjust the pose of the endoscope manually, which interrupts the surgery flow and lengthens the surgery time [1]. Many motor-driven endoscope holders have been proposed in literature [2], the surgeon interact with the robot with joystick, voice command, pedals or head movement [3–5]. However, there exists some drawbacks with these interacting methods, for example, joystick requires one of the surgeon’s hands, voice command is usually subject to interference and has long time-delay, foot pedals and head movement distract surgeon’s attention. Lin used a foot-attached IMU sensor to control an active robotic endoscopic holder, the inversion/eversion and abduction/adduction motions of foot are used to select and control different joints, but the motor can be only selected in order, which is unhandy for the four-joint scenario [6]. In this paper, a similar foot-attached IMU sensor is used, and the joints are selected in an easier manner, based on the angle of plantarflexion. Rather than the angle, the angular velocity of abduction/adduction is utilized to control the moving direction of the active joint. This paper describes the test result of the proposed control interface.
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10

Manral, Anshuman, und C. Praveen. „3 Fiber Line Switched Ring“. In OFC/NFOEC 2007 - 2007 Conference on Optical Fiber Communication and the National Fiber Optic Engineers Conference. IEEE, 2007. http://dx.doi.org/10.1109/ofc.2007.4348482.

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Berichte der Organisationen zum Thema "Lin-3"

1

Mulford, R. N. R. Calculation of the LiF-CeF{sub 3}-BeF{sub 2} and LiF-PuF{sub 3}-BeF{sub 2} ternary phase diagrams. Office of Scientific and Technical Information (OSTI), Juli 1993. http://dx.doi.org/10.2172/10176739.

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2

Kyser, E., und P. O'Rourke. INTERPRETATION OF AT-LINE SPECTRA FROM AFS-2 BATCH #3 FERROUS SULFAMATE TREATMENT. Office of Scientific and Technical Information (OSTI), Dezember 2013. http://dx.doi.org/10.2172/1111770.

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3

McVey, C. B. Functional design criteria radioactive liquid waste line replacement, Project W-087. Revision 3. Office of Scientific and Technical Information (OSTI), Oktober 1994. http://dx.doi.org/10.2172/10194713.

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4

Hrivnak, Jiri Hrivnak. Associated Lie Algebras and Graded Contractions of the Pauli Graded sl(3,C). Journal of Geometry and Symmetry in Physics, 2012. http://dx.doi.org/10.7546/jgsp-6-2006-47-54.

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5

Oneschuk, D., J. Tod und G. Kilfoil. Red Indian Line, airborne geophysics compilation (part II, Vol 1-3), central Newfoundland. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2002. http://dx.doi.org/10.4095/213230.

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6

Leigh, Richard J. Second Line of Defense: Electronic Maintenance Reports, Local Maintenance Provider User Guide, Rev. 3. Office of Scientific and Technical Information (OSTI), September 2012. http://dx.doi.org/10.2172/1074329.

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7

Pignataro, C., und M. Townsley. High-Level Data Link Control (HDLC) Frames over Layer 2 Tunneling Protocol, Version 3 (L2TPv3). RFC Editor, Februar 2006. http://dx.doi.org/10.17487/rfc4349.

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8

Kilroy, W. P., S. A. Chmielewski und D. W. Bennett. Investigation of Li/SO2 Cell Hazards. 3. Raman Spectroscopy of Lithium Dithionite. Fort Belvoir, VA: Defense Technical Information Center, September 1988. http://dx.doi.org/10.21236/ada205756.

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9

Adams, F. S., und M. R. Hunter. Action description memorandum for the FY 1991 line item: Environmental, Safety and Health Upgrades, Phase 3. Office of Scientific and Technical Information (OSTI), Februar 1989. http://dx.doi.org/10.2172/108083.

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10

Holmes, Gale A., Richard S. Parnas und Donald L. Hunston. Report on the industry workshop for on-line composite process monitoring, April 3 & 4, 1996. Gaithersburg, MD: National Institute of Standards and Technology, 1997. http://dx.doi.org/10.6028/nist.ir.6044.

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