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Zeitschriftenartikel zum Thema "Lapprya"
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Lin, Song-chow, Tsao-chuen Chung, Chun-ching Lin, Tzuu-Huei Ueng, Yun-ho Lin, Shuw-yuan Lin und Li-ya Wang. „Hepatoprotective Effects ofArctium Lappaon Carbon Tetrachloride- and Acetaminophen-Induced Liver Damage“. American Journal of Chinese Medicine 28, Nr. 02 (Januar 2000): 163–73. http://dx.doi.org/10.1142/s0192415x00000210.
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The root of Arctium lappa Linne (A. lappa) (Compositae), a perennial herb, has been cultivated for a long time as a popular vegetable. In order to investigate the hepatoprotective effects of A. lappa, male ICR mice were injected with carbon tetrachloride ( CCl4, 32 μl/kg, i.p.) or acetaminophen (600 mg/kg. i.p.). A. lappa suppressed the SGOT and SGPT elevations induced by CCl4or acetaminophen in a dose-dependent manner and alleviated the severity of liver damage based on histopathological observations. In an attempt to elucidate the possible mechanism(s) of this hepatoprotective effect, glutathione (GSH), cytochrome P-450 (P-450) and malondialdehyde (MDA) contents were studied. A. lappa reversed the decrease in GSH and P-450 induced by CCl4and acetaminophen. It was also found that A. lappa decreased the malondialdehyde (MDA) content in CCl4or acetaminophen-intoxicated mice. From these results, it was suggested that A. lappa could protect the liver cells from CCl4or acetaminophen-induced liver damages, perhaps by its antioxidative effect on hepatocytes, hence eliminating the deleterious effects of toxic metabolites from CCl4or acetaminophen.
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Jo, Hee-Geun, Geon-Yeong Lee, Chae Yun Baek, Ho Sueb Song und Donghun Lee. „Analgesic and Anti-Inflammatory Effects of Aucklandia lappa Root Extracts on Acetic Acid-Induced Writhing in Mice and Monosodium Iodoacetate-Induced Osteoarthritis in Rats“. Plants 10, Nr. 1 (26.12.2020): 42. http://dx.doi.org/10.3390/plants10010042.
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Osteoarthritis (OA) is an age-related joint disease and one of the most common degenerative bone diseases among elderly people. The currently used therapeutic strategies relying on nonsteroidal anti-inflammatory drugs (NSAIDs) and steroids for OA are often associated with gastrointestinal, cardiovascular, and kidney disorders, despite being proven effective. Aucklandia lappa is a well-known traditional medicine. The root of A. lappa root has several bioactive compounds and has been in use as a natural remedy for bone diseases and other health conditions. We evaluated the A. lappa root extracts on OA progression as a natural therapeutic agent. A. lappa substantially reduced writhing numbers in mice induced with acetic acid. Monosodium iodoacetate (MIA) was injected into the rats through their knee joints of rats to induce experimental OA, which shows similar pathological characteristics to OA in human. A. lappa substantially reduced the MIA-induced weight-bearing of hind limb and reversed the cartilage erosion in MIA rats. IL-1β, a representative inflammatory mediator in OA, was also markedly decreased by A. lappa in the serum of MIA rats. In vitro, A. lappa lowered the secretion of NO and suppressed the IL-1β, COX-2, IL-6, and iNOS production in RAW264.7 macrophages activated with LPS. Based on its analgesic and anti-inflammatory effects, A. lappa could be a potential remedial agent against OA.
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Alotaibi, Amal A., Asmatanzeem Bepari, Rasha Assad Assiri, Shaik Kalimulla Niazi, Sreenivasa Nayaka, Muthuraj Rudrappa, Shashiraj Kareyellapa Nagaraja und Meghashyama Prabhakara Bhat. „Saussurea lappa Exhibits Anti-Oncogenic Effect in Hepatocellular Carcinoma, HepG2 Cancer Cell Line by Bcl-2 Mediated Apoptotic Pathway and Mitochondrial Cytochrome C Release“. Current Issues in Molecular Biology 43, Nr. 2 (08.09.2021): 1114–32. http://dx.doi.org/10.3390/cimb43020079.
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Background and Objectives: Saussurea lappa (S. lappa) is an important species of the Asteraceae family with several purposes in traditional medicine. This study intended to explore the cytotoxic effect of S. lappa on HepG2 cancer cell proliferation. Materials and Methods: The effects of an S. lappa n-butanol extract on the induction of apoptosis were investigated by flow cytometry and mitochondrial cytochrome C-releasing apoptosis assay. Additionally, real-time PCR was employed to confirm apoptosis initiation. Further, qualitative estimation of the active constituent of S. lappa was done by gas chromatography–mass spectroscopy (GC–MS). Results: The cell viability study revealed that the n-butanol extract of S. lappa demonstrated potent cytotoxicity against HepG2 cancer cells, with an IC50 value of 56.76 μg/mL. Cell morphology with dual staining of acridine orange (AO)-ethidium bromide (EB) showed an increase in orange/red nuclei due to cell death by S. lappa n-butanol extract compared to control cells. Apoptosis, as the mode of cell death, was also confirmed by the higher release of cytochrome C from mitochondria, the increased expression of caspase-3 and bax, along with down regulation of Bcl-2. Conclusion: These findings conclude that S. lappa is a cause of hepatic cancer cell death through apoptosis and a potential natural source suggesting furthermore investigation of its active compounds that are responsible for these observed activities.
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Muhammad Ikbal und Muhammad Rudi. „PENGARUH FAKTOR EKONOMI TERHADAP PENJUALAN RUMAH SUBSIDI (STUDI KASUS DI PERUMAHAN BUMI LAPPA MAS KABUPATEN SINJAI)“. Jurnal Adz-Dzahab: Jurnal Ekonomi dan Bisnis Islam 4, Nr. 1 (20.05.2019): 50–61. http://dx.doi.org/10.47435/adz-dzahab.v2i1.344.
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Penelitian ini bertujuan untuk membuktikan pengaruh faktor ekonomi terhadap penjualan rumah subsidi di perumahan Bumi Lappa Mas dan untuk mengetahui besaran pengaruh faktor ekonomi terhadap penjualan rumah subsidi di perumahan Bumi Lappa Mas. Faktor ekonomi dalam mempengaruhi penjualan rumah subsidi di perupahan Bumi Lappa Mas merupakan daya yang timbul dari peristiwa yang mempengaruhi segala sesuatu yang berhubungan dengan tindakan ekonomi dalam pemenuhan kebutuhan masyarakat berupa faktor harga penjualan rumah, besarnya pembayaran angsuran/cicilan, dan tingkat pendapatan/penghasilan masyarakat terhadap penjualan rumah subsidi Bumi Lappa Mas Kabupaten Sinjai. Hasil penelitian ini menyimpulkan bahwa 1) Faktor ekonomi memiliki pengaruh positif dan signifikan terhadap penjualan rumah subsidi di perumahan Bumi Lappa Mas. Hal ini diperoleh berdasarkan analisis dengan menggunakan SPSS 16, diketahui t-hitung faktor ekonomi 7,732 > 2,020 (t-tabel) dan nilai probabilitas 0,000 < 0,05. 2) Besaran pengaruh faktor ekonomi terhadap penjualan rumah subsidi di perumahan Bumi Lappa Mas adalah 59% dan sisanya dipengaruhi oleh sebab-sebab lain (yang tidak diteliti). -2,647.
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Shaulo, Dmitry N., Elena Yu Zykova, Natalia N. Tupitsyna, Nina I. Molokova, Alexandra E. Sonnikova, Nadezhda V. Saak, Rada B. Shanmak, Anna D. Sambuu, Evgeny S. Ankipovich und Alexander I. Shmakov. „Floristic findings in the Upper Yenisei basin: Krasnoyarsk Territory, Republic of Tuva“. Turczaninowia 24, Nr. 1 (28.03.2021): 117–24. http://dx.doi.org/10.14258/turczaninowia.24.1.14.
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During field research, viewing materials stored in the herbaria of the Central Siberian Botanical Garden SB RAS (NS), Krasnoyarsk State Pedagogical University named after V. P. Astafyev (KRAS), the “Sayano-Shushensky” State Natural Biosphere Reserve (SSHZ) and the “Azas” State Nature Reserve, clarified information on the distribution of rare plant species in the Upper Yenisei basin. For the first time in the flora of the Krasnoyarsk Territory, 4 species were found: Allium eduardi, Ephedra gerardiana, Lappula tuvinica, Taraxacum sajanense; there are 5 species in Tuva: Kochia scoparia, Microstigma sajanense, Polygonum salsugineum, P. turkestanicum, Potentilla canescens. For the first time, 3 species were registered in the Western Sayan mountain system: Astragalus brevifolius, Kochia scoparia and Taraxacum sajanense. For 13 rare species, new locations were noted and the boundaries of the ranges were specified: Astragalus macroceras, Dontostemon pinnatifidus, Elymus pendulinus, Fritillaria dagana, Lappula heteracantha, L. semiglabra var. dsharkentica, L. tuvinica, Orchis militaris and others. The new ones for the “Sayano-Shushensky” State Natural Biosphere Reserve were 4 species: Allium eduardi, Elymus pendulinus, Ephedra gerardiana, Lappula tuvinica. Orchis militaris was first found for the “Azas” State Nature Reserve.
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Lin, Chun-Ching, Jer-Min Lin, Jeng-Jer Yang, Shu-Chuan Chuang und Takashi Ujiie. „Anti-inflammatory and Radical Scavenge Effects of Arctium lappa“. American Journal of Chinese Medicine 24, Nr. 02 (Januar 1996): 127–37. http://dx.doi.org/10.1142/s0192415x96000177.
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The effects of Arctium lappa L. (root) on anti-inflammatory and free radical scavenger activity were investigated. Subcutaneous administration of A. lappa crude extract significantly decreased carrageenan-induced rat paw edema. When simultaneously treated with CCl4, it produced pronounced activities against CCl4-induced acute liver damage. The free radical scavenging activity of its crude extract was also examined by means of an electron spin resonance (ESR) spectrometer. The IC50 of A. lappa extract on superoxide and hydroxyl radical scavenger activity was 2.06 mg/m 11.8 mg/m1, respectively. These findings suggest that Arctium lappa possess free radical scavenging activity. The inhibitory effects on carrageenan-induced paw edema and CCl4-induced hepatotoxicity could be due to the scavenging effect of A. lappa.
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Abd El-Rahman, Ghada I., Amany Behairy, Nora M. Elseddawy, Gaber El-Saber Batiha, Wael N. Hozzein, Dina M. Khodeer und Yasmina M. Abd-Elhakim. „Saussurea lappa Ethanolic Extract Attenuates Triamcinolone Acetonide-Induced Pulmonary and Splenic Tissue Damage in Rats via Modulation of Oxidative Stress, Inflammation, and Apoptosis“. Antioxidants 9, Nr. 5 (08.05.2020): 396. http://dx.doi.org/10.3390/antiox9050396.
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Background: In this era, worldwide interest has been directed towards using natural antioxidants to guard against drug side effects. Saussurea lappa is a famous medicinal plant with many biologically active compounds. Triamcinolone acetonide (TA) is an extensively used glucocorticoid. Hence, this study explored, for the first time, the possible beneficial effects of S. lappa ethanolic extract on TA-induced oxidative damage in the lung and spleen of rats. Methods: Five experimental groups were used: control group, S. lappa-treated group (600 mg/kg/day, orally), TA-treated group (40 mg/kg/twice/week I/P), S. lappa + TA co-treated group, and S. lappa/TA prophylactic group. Results: TA exposure significantly induced leukocytosis and neutrophilia. In addition, TA significantly reduced the levels of C-reactive protein, interleukin-12, tumor necrosis factor α, and immunoglobulins. Lung Caspase-3 overexpression and splenic CD8+ downregulation were also noted in the TA group. TA treatment significantly increased malondialdehyde concentration but reduced superoxide dismutase and glutathione peroxidase activities. S. lappa counteracted the TA oxidative and apoptotic effects. The best results were recorded in the prophylactic group. Conclusions: S. lappa has a remarkable protective effect via its anti-inflammatory, anti-apoptotic, and antioxidant capacity. Thus, it could be a candidate as a natural antioxidant to face glucocorticoid’s harmful side effects.
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Watanabe, Aya, Hiroyuki Sasaki, Hiroki Miyakawa, Yuki Nakayama, Yijin Lyu und Shigenobu Shibata. „Effect of Dose and Timing of Burdock (Arctium lappa) Root Intake on Intestinal Microbiota of Mice“. Microorganisms 8, Nr. 2 (06.02.2020): 220. http://dx.doi.org/10.3390/microorganisms8020220.
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Water-soluble dietary fiber such as inulin improves the beta diversity of the intestinal microbiota of mice fed with a high-fat diet (HFD). The circadian clock is the system that regulates the internal daily rhythm, and it affects the pattern of beta diversity in mouse intestinal microbiota. Burdock (Arctium lappa) root contains a high concentration of inulin/fructan (approximately 50%) and is a very popular vegetable in Japan. Arctium lappa also contains functional substances that may affect intestinal microbiota, such as polyphenols. We compared the effects of inulin and A. lappa powder on the diversity of the intestinal microbiota of HFD-fed mice. 16S rDNA from the intestinal microbiota obtained from feces was analyzed by 16S Metagenomic Sequencing Library Preparation. It was found to have a stronger effect on microbiota than inulin alone, suggesting that inulin has an additive and/or synergic action with other molecules in A. lappa root. We examined the effects of intake timing (breakfast or dinner) of A. lappa on intestinal microbiota. The intake of A. lappa root in the evening had a stronger effect on microbiota diversity in comparison to morning intake. Therefore, it is suggested that habitual consumption of A. lappa root in the evening may aid the maintenance of healthy intestinal microbiota.
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Idrissova, G. Z., I. V. Sergeeva, E. N. Shevchenko, A. L. Ponomareva und K. M. Akhmedenov. „Bioecological Characteristics of the Flora of the Territories Adjacent to the Springs of Western Kazakhstan“. Povolzhskiy Journal of Ecology, Nr. 4 (14.02.2020): 419–31. http://dx.doi.org/10.35885/1684-7318-2019-4-419-431.
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The data of floristic studies of 40 spring tracts of the Mangistau, Aktobe, Atyrau and West Kazakhstan regions of the Western Region of the Republic of Kazakhstan are presented. We have found that the studied flora is represented by 252 species, 167 genera and 55 families belonging to Equisetophyta, Pinophyta, and Magnoliophyta divisions. Taxonomic characterization of the flora showing the predominance of the Asteraceae and Poaceae families is provided. The predominance of perennial herbaceous plants in the flora of spring tracts was identified by the system of I. G. Serebryakov’s life forms. The predominance of steppe plants and weeds was revealed. Horological analysis showed the leading set of species with the Eurasian range type. Ecological characteristics highlighted the predominance of xerophytes and mesotrophic plants. 20 protected plant species listed in the Red Data Book of the Russian Federation and the Red Data Book of the Republic of Kazakhstan were identified. Analysis of the distribution of plants in the areas adjacent to the springs identified four grades of occurrence, namely: common species – 7; uncommon species – 17; rare species – 100; and very rare species – 128. The most common species found within the spring tract territories are related to weeds, such as Tripleurospermum perforatum (Merat) M. Lainz, Polygonum aviculare L., Taraxacum officinale Wigg., Lappula squarrosa (Retz.) Dumort., Plantago major L., Arctium lappa L., Xanthium strumarium L., Capsella bursa-pastoris (L.) Medik., Chenopodium album L., Convulvus arvensis L., Poa annua L., Bromus squarrosus L., Elytrigia repens (L.) Nevski. The Jaccard index (Kj) for the analyzed floras in pairwise comparison varies from 0.02 to 0.5, which shows the extreme heterogeneity of the specific composition.
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Fellman, Jacob. „The Thief and the Shaman“. Nordlit 8, Nr. 1 (01.07.2004): 5. http://dx.doi.org/10.7557/13.1904.
Der volle Inhalt der QuelleDissertationen zum Thema "Lapprya"
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Hakanen, Eva. „Återbrukets estetik - Uppländska trasryor : Förekomst, tillverkning, funktion och värde“. Thesis, Uppsala universitet, Textilvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-439775.
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Since the beginning of the early 20th century bed rugs have been interesting research objects, but only in passing researchers have paid attention to rugs woven with rags. Noone has taken a closer look upon the reasons why people have woven these rugs. What does the materials of the rag – like recycled garments and interior textiles in the form of clothing rags – have to tell about the times when these rugs were woven? Did the rag rugs have any specific function or were the materials available and therefore used? The main sources of information are 21 rag rugs from Roslagen in Uppland, with a varied amount of rags. They were woven during the latter half of 19th century, and estate inventories from Väddö- and Häverö Ship District have altogether given some answers to the primary question of this paper: in wich way can the examined bed rugs bear witness to the use and value of recycled textile materials and the view of these in the context of the community where they were manufactured and used? This research doesn´t give an answer to whether these rugs have any particular function or not. Instead these rag rugs can be looked upon as representing a general development of the society towards an increasing amount of textiles surplus material. This being due an increasing consumption of factory-made clothing and textiles, manufactured in factories, as well as the paper mills development from producing paper made of cellulose rather than textile waste. To this we can add a principle lingering on from the 19th century, of domestic production and a thrift of resources. This resulted in an obvious recycling of discarded textiles. The home weaving of interior textiles was still strong by the end of the 19th century, and in Rosagen there was also a long tradition of weaving and of using rugs in the beds. At the same time there was, in the coastal regions of Roslagen, a local need for warming covers in boats and boat houses. This demand was related to the shooting of seals and other hunting in the coastal areas, as well as in the fishing- and maritime trades.
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Rolfsmeier, Susan J. „Taxonomy and phylogeny of the genus Lappula Moench (Boraginaceae) in North America“. Diss., Kansas State University, 2012. http://hdl.handle.net/2097/15174.
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Doctor of PhilosophyDivision of Biology
Carolyn J. Ferguson
The genus Lappula Moench is a diverse group of herbaceous plants in the large, cosmopolitan family Boraginaceae. Over sixty species are recognized in Eurasia; many are found in cold deserts, steppes, and semi-deserts of Central Asia. Fewer species were described from western North America, and compared with the Asian species they are poorly known. Various North American taxa have been placed into synonomy under Eurasian species, and complex patterns of variation have made species circumscription challenging. The goal of this dissertation was to explore phylogenetic relationships between North American and Eurasian species and to revise the taxonomy of the North American species. A molecular phylogenetic study was initiated in order to infer patterns of relationships among the North American species relative to Eurasian diversity. Samples were collected from throughout the western United States and from Siberia. Additional samples of Eurasian species were taken from herbarium specimens. Sequences were generated for three DNA regions (the ITS region of the nuclear ribosomal DNA, and chloroplast intergenic spacers trnS-trnG and rpl32-trnL) and phylogenies were generated using parsimony and Bayesian analyses. Results were in general agreement among all analyses. The genus Lappula was recovered as a monophyletic group, with the exception of the morphologically anomalous L. sessiliflora (Boiss.) Gürke, which was sister to the genus Rochelia Rchb. The native North American species of Lappula and L. redowskii (Hornem.) Greene formed a clade. Samples of L. squarrosa (Retz.) Dumort., a Eurasian steppe plant with a wide introduced range in North America, grouped with samples from Eurasia. Sampled species of Hackelia Opiz, a genus sometimes treated as part of Lappula, formed a clade separate from the Lappula species sampled here. Herbarium and field studies resulted in a revised taxonomy for the North American Lappula. Nomenclatural problems were resolved; nine native species and four varieties were recognized along with the introduced Eurasian species L. squarrosa.
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Predes, Fabricia de Souza. „Efeito antioxidante da bardana (Arctium lappa) no testículo, epidídmo e fígado de ratos danificados pelo cádmio : bioquímica, morfometria e ultraestrutura“. [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317834.
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Orientador: Mary Anne Heidi Dolder, Mary Ann FoglioTese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Cádmio (Cd) é um metal pesado associado a graves danos em vários órgãos, incluindo órgãos reprodutivos e fígado. Estudos farmacológicos indicam que Arctium lappa possue atividade hepatoprotetora, sequestradora de radicais livres e antiproliferativa. O objetivo deste trabalho foi avaliar: (1) as modificações nos túbulos seminíferos causadas por pequenas doses de Cd, (2) as propriedades antioxidantes de diferentes extratos de A. lappa, (3) a capacidade de A. lappa em atenuar os danos induzidos por cádmio no testículo, epidídimo e fígado. A capacidade sequestradora de radicais livres e quantidade de compostos fenólicos totais foram analisados nos extratos da raiz de A. lappa para determinação da capacidade antioxidante. A propriedade antiproliferativa in vitro de cada extrato foi avaliada em células tumorais. O extrato hidroetanólico apresentou alto rendimento e capacidade sequestradora de radicais livres, e juntamente com os diclorometânicos, maior teor de compostos fenólicos. Somente os extratos diclorometânicos apresentaram atividade antiproliferativa contra células tumorais. espectroscopia de massa revelou a presença dos compostos arctigenina, quercetina, ácido clorogênico e ácido caféico no extrato hidroetanólico. O extrato hidroetanólico liofilizado foi escolhido para os estudos in vivo. Para estudar os efeitos de Cd e A. lappa, ratos Wistar adultos foram distribuídos em quatro grupos: controle (C), extrato de A. lappa (Al), cádmio (Cd) e cádmio e extrato de Al (CdAl). Os animais receberam água ou extrato de Al (300 mg/Kg BW) por gavagem e dose única i.p. de salina ou 1,2 mg/kg de cloreto de cádmio. Os animais foram sacrificados após 7 e 56 dias. O Cd causou redução do peso do testículo, epidídimo e vesícula seminal, na proporção dos túbulos seminíferos (TS), no comprimento total dos TS e no diâmetro dos TS. Células germinativas degeneradas e células gigantes multinucleadas foram observadas nos TS e os danos progressivos resultaram em túbulos preenchidos apenas com células de Sertoli. Nos grupos Cd e CdAl, houve diminuição da proporção tubular e aumento da altura do epitélio no epidídimo após 56 dias. Cd causou aumento no nível plasmático de TGO e TGP após 56 dias, mas o extrato de A. lappa amenizou estes efeitos. Nenhuma alteração relevante foi observada para as transaminases hepáticas. No grupo Cd 7 dias, a proporção de hepatócitos diminuiu, a de sinusóides aumentou e o número de núcleo de hepatócito reduziu, entretanto após 56 apenas o número de núcleos de hepatócitos diminuíram. Após 7 dias, nos grupos Al e CdAl, a proporção nuclear aumentou e a citoplasmática diminuiu, sem alteração dos capilares sinusóides. Após 56 dias, nos grupos Al e CdAl, a proporção nuclear aumentou e a proporção dos capilares sinusóides reduziu. Houve aumento na densidade de núcleos nos grupos Al e CdAl. Conclui-se que doses baixas de Cd causam alterações morfológicas e morfométricas no testículo e que o Cd tem sutil limiar tóxico. Os extratos diclorometânicos apresentaram atividade antiproliferativa contra as linhagens tumorais K562, MCF-7 e 786-0. O extrato hidroetanólico apresentou alto conteúdo fenólico e atividade antioxidante, portanto foi escolhido para os estudos in vivo. O extrato de A. lappa foi ineficaz na proteção do testículo e epidídimo contra danos induzidos pelo Cd, porém protegeu o tecido hepático.
Abstract: Cadmium (Cd) is a heavy metal associated with severe damage in various organs, including male reproductive organs and liver. Arctium lappa is widely used in popular medicine for treating hypertension, gout, hepatitis and other inflammatory disorders. Pharmacological studies indicated that A. lappa roots have hepatoprotective, free radical scavenging and antiproliferative activities. The objectives of this work were evaluate: (1) histomorphometrically the threshold modifications of seminiferous tubules caused by single acute low doses of Cd, (2) antioxidant properties of different A. lappa extracts to choose the best one for "in vivo" study, (3) the ability of A. lappa to attenuate cadmium-induced damage to the testis, epididymis and liver of male rats. Dichloromethanic, ethanolic, aqueous extracts, hydroethanolic and total aqueous extract of A. lappa roots were investigated regarding radical scavenging activity and the total phenolic content. The extracts were tested for their antiproliferative activity in vitro using human cancer cell lines. The higher radical scavenging activity and yield were found in the hydroethanolic extract. Higher phenolic contents were found in the dichloromethanic and hydroethanolic extracts. Only the dichloromethanic extracts exhibited activity against cancer cell lines. Highresolution electrospray ionization mass spectroscopy for the hydroethanolic extract demonstrated the presence of: arctigenin, quercetin, chlorogenic acid and caffeic acid. The hydroalcoholic lyophilized extract was chosen for the experiments in vivo. To study the association of Cd and A. lappa, adult Wistar rats were assigned to four groups: control (C), A.lappa extract (Al), cadmium (Cd) and cadmium plus A. lappa (CdAl). The animals received water or A. lappa hydroethanolic extract (300 mg/Kg BW) by gavage and i.p. injections of saline or 1.2 mg/Kg BW of cadmium chloride. The animals were sacrificed after 7 and 56 days of treatment. The Cd caused reduction in testis, epididymis and seminal vesicle weights, seminiferous tubule (ST) proportion, total length of ST and ST diameter. Degenerated germ cells and multinucleated aggregates were observed in ST and progressive damage resulted in tubules lined only with Sertoli cells. There was a decreased in tubular proportion and increased epithelial height in epididymis after 56 days. Cd caused an increase in plasma GOT and GPT levels after 56 days, but A. lappa extract improved these levels. No relevant alteration was observed in liver transaminase levels. After 7 days, the Cd group showed decrease in hepatocyte proportion and increase sinusoid capillary proportion, also the nuclear density decrease. However, after 56 days, only the hepatocyte nuclear density decreased. In Al and CdAl groups, after 7 days, the hepatocyte nuclear proportion increased and the cytoplasmic decreased, with no alteration in capillary sinusoid proportion. In Al and CdAl groups, after 56 days, hepatocyte nuclear proportion increased and the sinusoid capillary proportion decreased. Also, an increase of hepatocyte nuclear density was observed in Al and CdAl groups. This study revealed that low doses of Cd cause progressive morphological and morphometrical alterations on rat testis and that Cd has a subtle toxic threshold. The dichloromethanic extracts showed antiproliferative activity against K562, MCF-7 and 786-0 human cancer cell lines. The hydroethanolic extract showed higher free radical scavenger activity and higher phenolic content, and was chosen as the best extract for the "in vivo" studies. A. lappa hydroethanolic extract was ineffective in protecting the testis and epididymis against Cd-induced damage, however effectively protected liver tissue.
Doutorado
Biologia Celular
Mestre em Biologia Celular e Estrutural
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Almeida, Ana Beatriz Albino de. „Atividade antiulcerogenica e antiinflamatoria intestinal da Arctium lappa“. [s.n.], 2005. http://repositorio.unicamp.br/jspui/handle/REPOSIP/318126.
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Orientador: Alba Regina Monteiro Souza BritoTese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
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Resumo: Onodorpicrina, uma sesquiterpeno lactona, presente nas folhas de Arctium Lapa L. demonstrou através dos estudos de Barbosa et at (1993) erficaz atividade farmacológica. Com base nesses resultados e, devido ao fato, de nosso laboratório possuir estudos em relação à atividade antiulcerogênica de outras sesquiterpeno lactonas (desidrocrotonina e crotonina) obtidas das cascas de Croton cajucara Benth, decidimos estudar a atividade antiulcerogênica e antiinflamtória intestinal da fração semi-purificada (ONP), cujo composto majoritário é a onopordopicrina. Primeiramente estudamos o efeito da citotoxicidade da ONP avaliado através da viabilidade celular em fibroblastos (V79) de pulmão de Hamster chinês. A ONP apresentou IC50 aproximadamente de 15µM nos ensaios de MTT, vermelho neutro e conteúdo de ácido nucléico. Por ser uma substância com uma toxicidade relativa resolvemos estudar o efeito antitumoral dessa substância em linhagem celular de leucemia promielocítica (HL60) usada como modelo para estudos antitumorais. Da mesma forma que nos ensaios de citotoxidade, a ONP apresentou IC50 aproximadamente de 15 µM em ensaios de MTT e PTP. Para avaliar a atividade antiulcerogênica da ONP, foram utilizadas diferentes doses em modelos clássicos de indução de úlcera: etanol/HCl, estresse por imobilização e frio, indometacina e ligadura de piloro. Em todos os modelos a ONP apresentou atividade antiulcerogênica significativa. Nos procedimentos seguintes, avaliamos a atividade antisecretora da ONP através de ensaios de somatostatina e gastrina, nos quais a substância apresentou aumento da liberação e/ou produção de somatostatina e diminuição da produção e/ou liberação de gastrina. Em relação ao estudo da ONP em experimentos de muco e óxido nítrico, essa não apresentou diferença significativa. No entanto, promoveu diferença significativa no modelo de avaliação do envolvimento de radicais sulfidrila, indicando uma possível atividade antioxidante. Quando avaliada em modelo de colite ulcerativa induzida por TNBS, a ONP apresentou significativa proteção provavelmente pelo envolvimento da mieloperoxidase (MPO) e fator de necrose tumoral (TNF-alfa). Visto a atividade obtida com a ONP, resolvemos analisar a atividade do chá de Arctium lappa, o qual apresentou significativa envolvimento com óxido nítrico e grupamento sulfidrila para a obtenção da atividade antiulcerogência promovida pelo chá. Os resultados obtidos com a Arctium lappa são promissores, por causa de sua significativa proteção contra úlceras induzidas por diferentes agentes, sugerindo um efeito antisecretor mediado por sua ação na secreção de Somatostatina e Gastrina e um efeito protetor proporcionado pela propriedade antioxidante presente na ONP. Os dados também revelaram que o pré-tratamento com ONP é capaz de reduzir a inflamação intestinal produzida através do modelo de indução de colite ulcerativa por TNBS em ratos. O efeito agudo antiinflamatório provavelmente está relacionado com a diminuição de neutrófilos e diminuição da produção de TNF-a na mucosa intestinal. Nossos resultados sugerem um significativo potencial terapêutico da ONP na area gastrointestinal
Abstract: Onodorpicrin, a sesquiterpene lactone, present in the leaves of Arctium lappa L., showed through the studies of Barbosa et al (1993) effective pharmacological activity. Based on those results and due to the fact that our laboratory has studies in relation to the antiulcerogenic activity of other sesquiterpene lactone (dehydrocrotonin and crotonin) obtained by barks of Croton cajucara Benth, we decided to study the antiulcerogenic activity and bowel antiinflamatory of the semi-purified fraction (ONP), which majority compound is the onopordopicrin. Firstly we studied the effect of the citotoxicity of appraised ONP through the cellular viability in fibroblast (V79) of lung of Chinese Hamster. ONP presented IC50 approximately of 15µM in the MTT, red neutral and content of nucleic acid experiments. For being a substance with a relative toxicity we decided to study the effect antitumoral of that substance in cellular lineage of promyelocytic leukemia (HL60) used as model for antitumoral studies. In the same way that in the citotoxicity experiments, ONP presented IC50 approximately of 15 µM in experiments of MTT and PTP. To evaluate the antiulcerogenic activity of ONP, different doses were used in classic models of ulcer induction: ethanol/HCl, stress for immobilization and cold, indometacin and pylorus ligature. In all of the models ONP presented significant antiulcerogenic activity. In the following procedures, we evaluated the activity antisecretory of ONP through somatostatin and gastrin experiments, in which the substance presented increase of the liberation and/or somatostatin production and decrease of the liberation and/or gastrin production. In relation to the study of ONP in mucus experiments and nitric oxide, that one didn't present significant difference. However, it showed significant difference in the model of evaluation of the involvement of radicals sulphydryl, indicating a possible antioxidant activity. When evaluated in model of colitis ulcerative induced by TNBS, ONP presented significant protection probably for the involvement of the mieloperoxidase (MPO) and factor of necrosis tumoral (TNF-alpha). Checked the activity obtained with ONP, we decided to analyze the activity of the tea of Arctium lappa, which presented significant involvement with nitric oxide and sulphydryl group for the obtaining of the antiulcerogenic activity promoted by the tea. The results obtained with Arctium lappa are promising, because the significant protection against ulcers induced by different agents suggesting a effect antisecretory mediated through somatostatin and gastrin secretion and protective effect by the antioxidant properties present in ONP. The data also reveals that pre-treatment with ONP is able to reduce intestinal inflammation in theTNBS model of colitis in rats.The acute antiinflamatory effects seem to be related to impairment of neutrophil function and absence of up-regulation of TNF-a production in intestinal mucosa. Our findings suggest that ONP shows an excellent potential for therapy in the gastrointestinal area
Doutorado
Fisiologia
Doutor em Biologia Funcional e Molecular
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Carlotto, Juliane. „Estudo químico e biológico de folhas de Arctium lappa“. reponame:Repositório Institucional da UFPR, 2013. http://hdl.handle.net/1884/30619.
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Resumo: Arctium lappa, conhecida popularmente como bardana, é uma planta medicinal originária do Japão e aclimatada no Brasil. Ela é utilizada na medicina popular para tratamento de infecções, inflamações, febre, problemas crônicos de pele, gota, cálculo renal, úlcera gástrica, queimaduras e outras enfermidades. Este trabalho apresenta a extração, purificação, caracterização estrutural e avaliação da atividade gastroprotetora e anti-inflamatória de polissacarídeos das folhas de A. lappa. Além disso, mostra o fracionamento bioguiado por atividade antiúlcera gástrica dos compostos de baixa massa molar. De maneira geral, as frações polissacarídicas apresentaram-se constituídas majoritariamente pelos monossacarídeos Rha, Ara, Glc, Gal e GalA e, de acordo com análises de RMN e metilação, são compostas por dois polissacarídeos principais: ramnogalacturonana tipo I (RG I) e arabinogalactana tipo II (AG II). Polissacarídicas de A. lappa apresentaram atividade anti-inflamatória, mas não apresentaram nenhum efeito gastroprotetor. A fração contendo compostos de baixa massa molar (fração FSE) apresentou-se composta principalmente por ácidos fenólicos, entre os quais os ácidos 1-O-cafeoilquínico, neo-clorogênico, clorogênico, crypto-clorogênico, 1,3-O-dicafeoilquínico, 3,4-O-dicafeoilquínico, 3,5-O-dicafeoilquínico e 4,5-O-dicafeoilquínico, além dos flavonóides rutina e quercetina-ramnosídeo. Esta fração apresentou atividade antiúlcera gástrica de maneira dose dependente. O processo de fracionamento bioguiado de FSE gerou uma única fração com efeito antiúlcera gástrica, a fração FSE-AE, composta principalmente por ácidos dicafeoilquínicos.
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Öberg, Gunnar. „Gotlandspressen och de grå lapparna : Statens Informationsstyrelses övervakning av de gotländska dagstidningarna under andra världskriget“. Thesis, Högskolan på Gotland, Institutionen för humaniora och samhällsvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hgo:diva-1337.
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Under andra världskriget vidtogs i Sverige ett antal åtgärder som gick på tvärs mot den traditionella svenska pressfriheten. Ett inslag i denna politik var inrättandet av Statens Informationsstyrelse, SIS, med uppgift att bland annat leda och övervaka den svenska pressen. Informationsstyrelsen har i efterhand blivit mest känd för de så kallade ”grå lapparna”, förtroliga meddelanden till tidningarnas redaktörer om vad som inte fick publiceras. Under kriget utkom på Gotland tre dagstidningar. Gotlänningen som ägdes av bondeförbundsintressen, konservativa Gotlands Allehanda vars huvudägare C E Ekman även var tysk konsul och tidningen har betraktats som mycket pronazistisk samt socialdemokratiska Gotlands Folkblad som framställts som ytterst anti-nazistisk. Utifrån SIS arkiv beskrivs SIS styrning av tidningarna genom de grå lapparna och påpekanden av överträdelser. Vidare har undersökts om SIS vidtog några åtgärder mot de gotländska tidningarna och om det i så fall var Gotlands Folkblads påstådda antinazism och/eller Gotlands Allehandas påstådda tyskvänlighet som SIS reagerade på. Resultatet visar att de allra mest som SIS reagerade på i de gotländska tidningarna var rena nyhetsartiklar. Inte i något enda fall klandrade SIS någon kommenterande artikel.During World War II a number of actions were taken contrary to the traditional Swedish freedom of the press. One of these actions was the establishment of “Statens Informationsstyrelse”, SIS, the Gouvernment Board of Information. SIS hade rhe task of managing and monitoring the Swedish press. It has subsequenly become known for the so-callade “grey notes”, cinfidential message to newspaper editors about what was not allowed to be published. There were three newspapers in Gotlands during World War II. “Gotlänningen” represented the farmer´s party. The right-wing Gotlands Allehanda, whose principal shareholder C E Ekman was also the German consul, was often portrayed as very pro-nazi. The social demofratic “Gotlands Folkblad” was, on the other hand, potrayed as anti-nazi. Based on the SIS archive, a review has been done about how SIS controlled the newspaperes and ruled through the greynotes and reprimands in case of transgressions. Furthermore an analysis has been done on the different reprimands SIS took aginst the Gotland newspapers and if the reprimands were taken in response to the alleged anti-nazism of Gotlands Folkblad or the allegeds pro-nazism of Gotlands Allehanda. The result show thar the vast majority of the articles SIS responded to in the Gotland newspapers were pure news articles. In no single case did SIS respond to a commentary article.
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Hu, Bizhen. „Metabolite Production in Callus Culture of Burdock (Arctium lappa L.)“. The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1357141954.
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Saço, Luana Carla. „Avaliação do potencial esquistossomicida da arctiina, extraída de Arctium lappa L“. Universidade Federal de Juiz de Fora (UFJF), 2015. https://repositorio.ufjf.br/jspui/handle/ufjf/3116.
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CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
A esquistossomíase é considerada uma das doenças tropicais negligenciada mais significativa no mundo. Sendo que a presença de apenas um medicamento para o tratamento da infecção leva a busca por novos compostos esquistossomicidas, utilizando os produtos naturais como uma das principais fontes destas novas moléculas. Neste sentido, a lignana Arctiina extraída da espécie Arctium lappa, cujas funções anti-inflamatórias e antiproliferativas já foram descritas na literatura, se tornou alvo do nosso estudo. O nosso propósito foi pesquisar a sua ação esquistossomicida através de testes in vitro e em modelo murino. A substância foi utilizada nas concentrações de 30, 60, 120 e 240 µg/mL nos ensaios in vitro. Após o período de incubação, em nenhuma das concentrações, a molécula foi capaz de promover modificação na viabilidade do parasito em cultura quando comparado ao grupo controle. Após a administração por via intraperitoneal, para verificar a presença da substância no plasma murino, foi realizada uma análise cromatográfica. A análise da amostra de arctiina pura, diluída em metanol, e diluída em plasma murino não tratado mostrou um pico no cromatograma medido a 254 nm, com retenção de 5 minutos. A amostra de plasma animal coletada após uma hora de tratamento com arctiina, sob as mesmas condições experimentais, revelou um pico semelhante ao da amostra pura, confirmando que a arctiina está disponível no plasma após administração. Os testes in vivo, foram realizados em camundongos fêmeas da linhagem Swiis que receberam por via intraperitoneal duas dosagens de arctiina (50 mg/kg), sendo a primeira administrada 20 dias após a infecção e a segunda após duas semanas. Nos parâmetros analisados: peso hepático, leucometria global, redução da carga parasitária e alteração no oograma, não foi verificado nenhuma alteração significativa em relação aos parâmetros encontrados no grupo controle infectado, tratado com praziquantel (200 mg/kg) e Dimetilsulfóxido (0,5%). O resultado mais promissor foi uma redução das médias das áreas dos granulomas, a administração da arctiina provocou uma redução em torno de 20% em comparação com o controle infectado. Mais estudos devem ser realizados a fim de verificar o possível mecanismo de atuação sobre os componentes inflamatórios presentes na formação do granuloma.
Schistosomiasis is one of the most significant neglected tropical diseases in the world. Only one drug is currently available for the treatment and control of schistosomiasis, therefore there is an urgent need for the development of new schistosomicide compounds, being natural products an important source of these molecules. Hence, in this work we studied the lignan arctiin extracted from Arctium lappa species, whose anti-inflammatory and antiproliferative functions have been previously described. Our aim was to investigate in vitro and in vivo its schistosomicidal activity. We tested the compound in vitro at the follow concentrations 30, 60, 120 and 240 ug/ml. There was no difference in all tested concentrations in the viability of the parasite in the culture after the incubation when compared to the control group. In addition we verified the plasmatic concentration of arctiin after intraperitoneal administration in mice by chromatographic analysis. The analysis of pure arctiin diluted in either methanol or mouse plasma showed a peak in the chromatogram at retention time of 5 minutes, absorbance was measured at 254 nm. Animal plasma sample collected one hour after treatment with arctiin was analyzed under same experimental conditions and revealed a similar peak, confirming the availability of arctiin in the plasma following administration. The in vivo tests were performed in Swiss female mice, those were intraperitoneally injected with two dosages of arctiin (50 mg/kg) - the first administered 20 days after infection and the second two weeks later. The follow parameters were analyzed: liver weight, white blood cell count, parasitic load and oogram. We did not find any significant change in those parameters comparing infected control groups treated either with praziquantel (200 mg / kg) or dimethyl sulfoxide (0.5 %) to the group treated with arctiin. The most promising result was the reduction around 20% of the average area of the granuloma in the arctiin group compared with the infected control. More studies are needed to verify possible mechanisms of action of this molecule in inflammatory components that play a role in granuloma formation.
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Dumartin, Véronique. „La grande Bardane (Lappa Major Gaertn. ) : utilisations en allopathie et en homéopathie“. Bordeaux 2, 1994. http://www.theses.fr/1994BOR2P037.
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Zhao, Jinlian. „Phytochemical and antibacterial studies on Arctium lappa, Tussilago farfara and Verbascum thapsus“. Thesis, University of Strathclyde, 2014. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=23623.
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This thesis described the isolation and structure elucidation of secondary metabolites from three medicinal plants selected on the basis of their traditional use in the treatment of infectious diseases. The work also focused on the evaluation of the plant extracts and some of the isolated compounds for activity in vitro against Mycobacterium tuberculosis. Compounds obtained in suffient yield were further tested for activity in vitro against Methicillin-resistant Staphylococcus aureus. A total of 27 pure compounds and two mixtures were isolated from the three plants investigated: Arctium lappa, Tussilago farfara and Verbascum thapsus. Phytochemical investigation of the aerial parts of A. lappa led to the isolation of four terpenoids (taraxasterol, taraxasterol acetate, isololiolide and melitensin), two steroids (sitosterol/stigmasterol mixture and daucosterol), three flavonoids (quercetin, kaempferol and kaempferol-3-O-glucoside), two phenolic acids or derivatives (caffeic acid and 1, 3-dicaffeoylquinic acid) and one alkane (n-nonacosane). Isololiolide, melitensin, kaempferol-3-O-glucoside and n-nonacosane are reported for the first time from this species, and daucosterol and kaempferol are first reported from the aerial parts of this plant. Phytochemical investigation of T. farfara aerial parts led to the isolation of a monoterpene lactone (loliolide), two steroids (sitosterol/stigmasterol mixture and daucosterol), three flavonoids (quercetin, kaempferol and kaempferol-3-O-glucoside), and six phenolic acids or derivatives (p-coumaric acid, p-coumaric acid/4-hydroxybenzoic acid mixture, caffeic acid, 3, 4-dicaffeoylquinic acid, 4, 5-dicaffeoylquinic acid and methylcaffeate). Among them, loliolide is reported for the first time from this species. The aerial parts of V. thapsus afforded two pheophorbides (pheophorbide A and pheophorbide A ethyl ester), two pheophytins (pheophytin A and pheophytin B), one steroid (a-spinasterol), one known flavonoid (luteolin), one phenylethanoid glycoside (verbascoside), three simple pheonolic acids (trans-cinnamic acid, 4-hydroxybenzoic acid and 4-hydroxy-3-methoxybenzoic acid) and one fatty acid (1-monoacylglycerol). All compounds, except for a-spinasterol, luteolin and verbascoside, are reported for the first time from this species. a-Spinasterol is first reported from the aerial parts of this plant. When screened for activity against M. tuberculosis in the SPOTi assay, A. lappa n-hexane extract and dichloromethane phase of methanol extact, and T. farfara n-hexane and ethyl actate extracts were active at MICs of 62.5 μg/mL; A. lappa ethyl acetate extract and T. farfara methanol extract were active at MICs of 125 μg/mL; V. thapsus ethyl acetate extract was active at the concentration of 250 μg/mL. Among the tested compounds isolated from active extracts, p-coumaric acid displayed the highest activity (MIC=31.3 (So(Bg/mL, 190.7 μM); p-coumaric acid/4-hydroxybenzoic acid mixture showed good activity (MIC=62.5 μg/mL); sitosterol/stigmasterol mixture exhibited moderate activity (MIC=125 μg/mL); loliolide, caffeic acid and trans-cinnamic acid revealed weak activity (MICs=250 μg/mL, or 1273.9, 1387.6 and 1687.4 μM, respectively). This is the first time that the antitubercular acitivity of A. lappa, T. farfara and V. thapsus has been investigated. The anti-TB activity of all tested compounds is also first reported in the SPOTi assay. When initially screened for activity against M. tuberculosis in the MABA assay at the highest concentrations of 25 or 50 μg/mL, all plant extracts and tested compounds were identified as inactive at such concentrations. This is the first report of the screening of A. lappa, T. farfara and V. thapsus extracts and of all tested compounds in the MABA assay. Among the compounds screened for activity against Methicillin-resistant S. aureus, luteolin exhibited good activity with an MIC valueof 62.5 μg/mL (218.3 μM), and a-spinasterol had an MIC of 500 μg/mL. No other compound was active at the highest concentration (500 μg/mL) used in this assay. This is the first report of the investigation of the anti-MRSA activity of kaempferol, a-spinasterol, 1, 3-dicaffeoylquinic acid, 3, 4-dicaffeoylquinic acid, 4, 5-dicaffeoylquinic acid, 1-monoacylglycerol, pheophorbide A ethyl ester, pheophytin A, pheophytin B and verbascoside.
Bücher zum Thema "Lapprya"
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Paulaharju, Samuli. Taka-Lappia. Helsinki: Suomalaisen Kirjallisuuden Seura, 2010.
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Laestadius, L. L. Fragmenter i lappska mythologien. Åbo: Nordic Institute of Folklore, NIF, 1997.
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Kamala, Bālaka Rāma. Lappa kiranāṃ dī. Jalandhara: Dīpaka Pabalisharaza, 1987.
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Bulgakov i Lappa. Moskva: Vagrius, 2008.
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Ikka lappa lāwā: Kawitāwāṃ, g̲h̲azalāṃ. Jalandhara: Kukanusa Prakāshana, 2006.
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Moutsopoulos, H. M. (Haralampos M.), Hrsg. Stichourgēmata tou "Bampa Lappa" (1852-1939). Athēna: Ekdoseis Kapon, 2012.
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Khetarapāla, Rājindara. Ika lappa raushanī: Gīta ate g̲h̲azala. Caṇḍīgaṛha: Raghabīra Racanā Prakāshana, 1992.
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Antonsson, Bo. Med Via Lappia från hav och kust till skog och fjäll. Malung: Vägföreningen Via Lappia Sverigevägen, 1992.
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Tomasson, Torkel. Några sägner, seder och bruk, upptecknade efter Lapparna i Åsele- och Lycksele lappmark samt Herjedalen sommaren 1917. Uppsala: Dialekt- och folkminnesarkivet, 1988.
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H, Sudharto P. Motorisasi dan perubahan sosial: Studi kasus di Desa Lappa dan Samataring, Kabupaten Sinjai. Ujung Pandang: Pusat Latihan Penelitian Ilmu-Ilmu Sosial, Universitas Hasanuddin, 1989.
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Azimova, Shakhnoza S., und Anna I. Glushenkova. „Lappula granulate“. In Lipids, Lipophilic Components and Essential Oils from Plant Sources, 160. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_529.
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Azimova, Shakhnoza S., und Anna I. Glushenkova. „Lappula redowskii (Hornem.) Greene (Lappula intermedia (Ledeb.) M. Pop.)“. In Lipids, Lipophilic Components and Essential Oils from Plant Sources, 160–61. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_531.
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Azimova, Shakhnoza S., und Anna I. Glushenkova. „Lappula barbatum (Bieb.) Guerke“. In Lipids, Lipophilic Components and Essential Oils from Plant Sources, 159. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_527.
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Bährle-Rapp, Marina. „Arctium lappa“. In Springer Lexikon Kosmetik und Körperpflege, 44. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_775.
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Lim, T. K. „Arctium lappa“. In Edible Medicinal and Non Medicinal Plants, 655–86. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9511-1_20.
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Khare, C. P. „Arctium lappa Linn.“ In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_142.
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Bussmann, Rainer W., Ketevan Batsatsashvili, Zaal Kikvidze, Narel Y. Paniagua-Zambrana, Manana Khutsishvili, Inesa Maisaia, Shalva Sikharulidze und David Tchelidze. „Arctium lappa L.Asteraceae“. In Ethnobotany of Mountain Regions, 1–8. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-77088-8_14-2.
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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott und R. W. Briddon. „Arctium lappa (Greater burdock)“. In Encyclopedia of Plant Viruses and Viroids, 184–86. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_77.
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Bussmann, Rainer W., Ketevan Batsatsashvili, Zaal Kikvidze, Narel Y. Paniagua-Zambrana, Manana Khutsishvili, Inesa Maisaia, Shalva Sikharulidze und David Tchelidze. „Arctium lappa L. Asteraceae“. In Ethnobotany of Mountain Regions, 119–26. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-28940-9_14.
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Azimova, Shakhnoza S., und Anna I. Glushenkova. „Lappula echinata Gilib. (L. squarrosa (Retz.) Dumort.)“. In Lipids, Lipophilic Components and Essential Oils from Plant Sources, 160. London: Springer London, 2012. http://dx.doi.org/10.1007/978-0-85729-323-7_528.
Der volle Inhalt der QuelleKonferenzberichte zum Thema "Lapprya"
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Souto, D., A. Faina, F. Lopez-Pena und R. J. Duro. „Lappa: A new type of robot for underwater non-magnetic and complex hull cleaning“. In 2013 IEEE International Conference on Robotics and Automation (ICRA). IEEE, 2013. http://dx.doi.org/10.1109/icra.2013.6631053.
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Choodej, S., und K. Pudhom. „In vitro anti-melanogenisis effect of sesquiterpene lactones from roots of Saussurea lappa and their analogues“. In 67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP. © Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-3400048.
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„Growth, Yield and Phytochemical Constituents of Arctium lappa L. in Response to Phosphorous and Potassium Fertilizers Application“. In Nov. 16-17, 2020 Johannesburg (SA). Eminent Association of Pioneers, 2020. http://dx.doi.org/10.17758/eares10.eap1120122.
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Jiqing Du, Zhiqiang Li, Yang Xiao und Feilong Li. „Iterative-LAPPR-statistic-decision-aided algorithm: A method for carrier phase synchronization and decoding in turbo-coded systems“. In 2011 International Conference on Computer Science and Service System (CSSS). IEEE, 2011. http://dx.doi.org/10.1109/csss.2011.5974756.
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KOLBINA, Anastasia Y., Marina G. KURBANOVA und Roman A. VOROSHILIN. „Prospects for the Use of Arctium Lappa L Extract in the Production of Candy Caramel for Diabetic Nutrition“. In IV International Scientific and Practical Conference "Modern S&T Equipments and Problems in Agriculture". Sibac, 2020. http://dx.doi.org/10.32743/kuz.mepa.2020.108-115.
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MANTOVANI CELEGATTI, CAROLINE, Maria Teresa Pedrosa Silva Clerici und Thaísa Menezes Alves Moro. „Burdock root (Arctium lappa, L.) flours produced by air conventional drying and freeze-drying and its application in cookies“. In XXIV Congresso de Iniciação Científica da UNICAMP - 2016. Campinas - SP, Brazil: Galoa, 2016. http://dx.doi.org/10.19146/pibic-2016-51453.
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Andika, B. „Characteristics of Facies Associations, Ichnofacies and Microfossils for Depositional Environment Interpretation of The Clastic Pulau Balang Formation, Samarinda“. In Digital Technical Conference. Indonesian Petroleum Association, 2020. http://dx.doi.org/10.29118/ipa20-sg-12.
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The Kutai Basin contains prolific reserves of oil and gas. The study of depositional environments is one of the goals of oil and gas exploration. The location of this research is situated in the Tanah Merah area, Samarinda. The objective of this research was to analyse outcrops of the Pulau Balang Formation exposed in the Tanah Merah area to determine the depositional environment. Site specific studies were conducted at 3 localities in this area; TM1, TM2 and TM3. This study combines geological mapping, measured sections, facies analysis, petrography, ichnofacies analysis and microfossil analysis. Geological mapping was carried out to determine the distribution of rock units and geological structures. Measured sections were used for facies analysis and the identification of sedimentary structures and ichnofacies. Petrography was carried out to determine the mineral content of rocks and microfossil analysis for palaeobathymetric environmental analysis. The geological structure of the study area comprises a NE-SW trending anticline and syncline and a left lateral strike-slip fault with E-W direction. The study area is entirely within the Middle Miocene age Pulau Balang Formation and can be divided into three facies associations. The TM1 facies association comprises strata interpreted to be deposited in a supratidal marsh and intertidal flat environment. The TM2 facies association comprises strata interpreted to be deposited in a subtidal, intertidal, and supratidal environment. The TM3 facies association comprises strata interpreted to be deposited in a shoreface environment. The petrography of the study area indicates that rock units predominantly comprise quartz wacke and lithic wacke. Two ichnofacies were identified in the research area 2, namely the Skolithos ichnofacies and the Skolithos-Cruziana ichnofacies and contain ichnogenera namely Ophiomorpha, Skolithos, Planolites, Thalassinoides, Paaleophycus. Microfossil analysis found benthonic foraminifera species including Nodosaria lamellala, N. radicula, Vaginulinopsis tricarinata, Lagena costata, Striatissima vaginulina, Bulimina lappa, Planularia auris, Quinqueloculina seminulum, Bolivina punctata and Lahena laevis. Based on the presence of these microfossils and ichnofacies, it is interpreted that the research area was deposited in a neritic-bathyal environment.