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Auswahl der wissenschaftlichen Literatur zum Thema „Kabi“
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Zeitschriftenartikel zum Thema "Kabi"
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Boboqulova, Uljon. „Mo‘tabar siymoning samoviy olami“. Узбекистан: язык и культура 1, Nr. 1 (04.04.2024): 59–67. http://dx.doi.org/10.47689/ulac-vol1-iss1-y2024-pp59-67.
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Ona siymosi har bir adib ijodiga alohida bir mehr, chinakam ehtirom hosilasi sifatida kirib keladi. Bu ehtirom undagi beqiyos fazilatlar va xislatlarga bo'lgan maslak bilan ifodalanadi. "Ona haqida kimlar nima demagan. Dunyoda Oripov biror bir shoir yoki adib bo'lmasinki, ona haqida qo'shiq to'qimagan, kuylamagan bo'lsa. Ona bor, olam bor; ona bor, odam bor; ona bor, Vatan bor, deyishadi. Chindan ham ona kabi tabarruk va aziz, ona kabi muqaddas va mehridaryo, ona kabi mard va jasur, ona kabi hokisor va kechirimli inson olamda topilmasa kerak. Shundan bo'lsa ajab emaski, ona mavzusi ijodkor uchun navqiron, abadiy tugallanmas ilhom manbayidir",-degan edi adabiyotshunos olim S.Mirvaliyev ona qiyofasi to'g'risidagi mulohazalarida. Ushbu maqola ona obrazining lirik va irfoniy talqin muammosini shoir Abdulla Oripov she'riyatida misolida o'rganishni ko'zda tutadi.
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Agnelli, Giancarlo, Judocus Borm, Benilde Cosmi, Marcel Levi und Jan Wouter ten Cate. „Effects of Standard Heparin and a Low Molecular Weight Heparin (Kabi 2165) on Fibrinolysis“. Thrombosis and Haemostasis 60, Nr. 02 (1988): 311–13. http://dx.doi.org/10.1055/s-0038-1647051.
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SummaryPrevious and recent reports have suggested a fibrinolysisenhancing property of standard heparin and low molecular weight heparins, but these observations have never been confirmed in a study fulfilling appropriate methodological criteria. The aim of this study was to evaluate the effect of standard heparin and a low molecular weight heparin (Kabi 2165) on fibrinolysis in a randomized cross-over double blind placebo controlled study. Six healthy volunteers received intravenously a bolus dose of the following treatments: placebo; standard heparin, 5,000 I.U.; Kabi 2165, 5,000 anti-Xa U; Kabi 2165,10,000 anti-Xa U. Before the injection and at established times thereafter, blood samples were collected for the following assays in plasma: t-PA activity, PA inhibitor activity, fibrin plate lysis area (FPLA), plasminogen, α2-antiplasmin, fibrinogen and anti-Xa activity. Placebo and Kabi 2165, 5,000 anti-Xa U, had no effect on t-PA plasma level. Standard heparin and Kabi 2165, 10,000 anti-Xa U, produced a statistically significant increase in t-PA level at 1 hour after the infusion. This increase lasted for at least 1 hour after the infusion. No effect of any treatment on PA inhibitor, plasminogen, FLPA, α2-antiplasmin and fibrinogen was observed. We conclude that an intravenous bolus dose of both standard heparin, 5,000 I.U. and Kabi 2165, 10,000 anti-Xa U produces a delayed and sustained increase in plasma t-PA.
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O’Brien, J. R., M. D. Etherington und Michelle A. Pashley. „The Heparin-Mobilisable Pool of Platelet Factor 4: A Comparison of Intravenous and Subcutaneous Heparin and Kabi Heparin Fragment 2165“. Thrombosis and Haemostasis 54, Nr. 04 (1985): 735–38. http://dx.doi.org/10.1055/s-0038-1660121.
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SummarySome clinical advantages are claimed for low molecular weight heparin so the mobilisation of platelet factor 4 (PF 4) from the endothelial pool by the heparins may be relevant. Unfractionated (UF) heparin has been compared with Kabi heparin fragment 2165. A single intravenous (i. v.) injection of 60 iu/kg heparin was compared with 5000 anti-Xa units of Kabi-2165. Less PF 4 was mobilised by Kabi-2165 and some apparently remained in the pool and was released when the pool was subsequently challenged by giving i.v. heparin. Subcutaneous (s. c.) injections of 5000 iu heparin twice daily were compared with 5000 anti-Xa units of Kabi-2165 once daily, each given for a week. The plasma PF 4 was never raised yet when finally challenged with i.v. heparin the pool was “empty” or refractory after the s.c. heparin but some PF 4 remained after the s.c. Kabi-2165. The two glycosaminogly-cans (GAGs) had widely differing half-lives but the t/2 of the PF 4 mobilised by the two GAGs was similar even though the PF 4 is apparently bound to the GAG.
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X u d a y b e r g a n o v, R. „An’anaviy tafakkur inersiyasini bartaraf etishning kommunikativ asoslari“. 2022-yil, 3-son (133/1) ANIQ FANLAR SERIYASI 2, Nr. 126/1 (06.03.2021): 1–9. http://dx.doi.org/10.59251/2181-1296.v2.1261.1525.
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. Mazkur maqolada an’anaviy tafakkur inersiyasini bartaraf qilishda tilning tabiiyilmiy va madaniy-tarixiy jihatlari bilan bog‘liq holatlar tahlil qilingan. Shuningdek, insonlar o‘rtasida kommunikativ tafakkurni amalga oshirish hamda kommunikativ bilimlarini rivojlantirishda tafakkurning til va nutq kabi vositalari insonlararo muloqotning ijtimoiylashuvga xizmat qilishi kabi masalalar yoritib berilgan.
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Y i l m a z, T. u. g. b. a. „ABDULLA ORIPOV SHE’RLARIDAGI TARIXIY SHAXSLAR“. 2022-yil, 3-son (133/1) ANIQ FANLAR SERIYASI 2, Nr. 132/2 (02.03.2022): 1–8. http://dx.doi.org/10.59251/2181-1296.v2.1322.62.
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Sovet va mustaqillik davri o‘zbek adabiyotining muhim namoyandalaridan biri Abdulla Oripov she’r, doston, maqola, ocherk, tarjima kabi ko‘plab janrlarda asarlar yaratgan. Falsafiy chuqurlik, axloqiylik, xushmuomalalik, she’r, shoir, vatanparvarlik, til, din, istiqlol, adolat, tarixiy shaxslar, tabiat, oila, qarindosh-urug‘chilik kabi ko‘plab mavzularda qalam tebratgan A. Oripov she’rlarining mazmuni boyligi va rang-barangligi bilan ahamiyatlidir. Oripovning asarlarida; vatan, millat, til, bayroq kabi muqaddas mavzularga ko'pincha uchraydi. U o‘z xalqining milliy o‘zligini shakllantirishni ta’minlash, tarixiy shaxslarni kitobxonlarga yetkazishni maqsad qilgan. Koʻpgina sheʼrlarida Oʻzbekistonning madaniy xususiyatlari, geografik goʻzalliklari haqida soʻz boradi. Bundan tashqari, shoir o‘z she’rlarida qadimgi o‘zbek tarixining eng muhim shaxslarini tilga oladi. U o‘z asarlarida o‘z xalqining o‘tmishi bilan faxrlanishini tez-tez ta’kidlaydi. Bu tadqiqotda Abdulla Oripovning Beruniy, Ulug‘bek, Ahmad Yassaviy, Amir Temur, Alisher Navoiy, Bobur, Mo‘min Mirzo, Abdurauf Fitrat, Abdulhamid Sulaymon Cho‘lpon, Abdulla Qodiriy, Muso Toshmuhammedog‘lu Oybek, Abdulla Qahhor, Hamid Olimjon, Zulfi Ko‘pchilik Asqad Muxtor, G‘afur G‘ulom, Hamza Hekimzoda Niyazi kabi muhim tarixiy shaxslar haqida so‘z boradi.
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M u s u r m a n o v, E. „O‘ZBEK VA XITOY MIFOLOGIYASIDA BOSH TOTEMISTIK TUSHUNCHALAR TALQINI“. 2022-yil, 3-son (133/1) ANIQ FANLAR SERIYASI 4, Nr. 122/2 (05.05.2020): 1–9. http://dx.doi.org/10.59251/2181-1296.v4.1222.995.
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Maqolada qadimgi o‘zbek mifologiyasidagi totemistik qarashlar, muqaddas bilingan bo‘ri, bars kabi jonivorlarning mifologik talqinlari haqida so‘z yuritildi. Bu xil tushunchalarning paydo bo‘lishida ma’lum bir tarixiy va migratsion jarayonlar o‘z ta’sirini o’tkazgan. Garchi o‘zbek xalqi orasida totem hayvonlar ko‘plab uchrasada, ularning hech biri bo‘ri kabi muhim o‘rin tutmaydi.
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A Fayziyeva, A. „INGLIZ SHAXSIY RIVOJLANISH LINGVODISKURSIDA HAYOT BILAN BOG‘LIQ KONSEPTUAL METAFORALAR“. 2022-yil, 3-son (133/1) ANIQ FANLAR SERIYASI 6, Nr. 136/2 (03.07.2022): 1–10. http://dx.doi.org/10.59251/2181-1296.v6.1362.1417.
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Mazkur maqolada ingliz tilida yaratilgan shaxsiy rivojlanish adabiyotlarida qo‘llanilgan hayot konseptiga oid konseptual metaforalar tahlili keltirilgan. Insonning hayot kabi mavhum tushunchalarni anglashi, uni kommunikasiyada verballashtirishi turli konseptual metaforalar yordamida amalga oshiriladi, jumladan, hayot – sayohat, hayot – yo‘l, hayot – hikoya, hayot – kurash kabi metaforik modellar tahlil qilingan asarlarda eng ko‘p uchradi.
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Mamurova, Mohlaroy Ma`rufjon qizi, und Sharifa Akramovna Matamirova. „YALPIZ TARKIBIDAGI AYRIM BIOLOGIK FAOL BIRIKMALAR VA ULARNING AHAMIYATI“. Журнал химии товаров и народной медицины 1, Nr. 1 (02.04.2022): 164–79. http://dx.doi.org/10.55475/jcgtm/vol1.iss1.2022.9.
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Ushbu maqolada yalpiz o‘simligi (Mentha piperita L.) o‘simligi tarkibiga kiruvchi efir moylari, oshlovchi moddalar, terpenlar, aromatik birikmalar kabi ayrim biologik faol birikmalar to‘g‘risida ma’lumotlar keltirilgan. Shuningdek, maqolada yalpizning shifobaxshlik xususiyatlari va asab kasalliklari, ateroskleroz, gipertonik kasaliklari, yuqori nafas organlarining shamollashi, migren, xolesistit, stenokardiya va shu kabi boshqa ko‘plab kasalliklarni davolashdagi ahamiyati to‘g‘risida ham so‘z yuritilgan.
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Mamatqulova, Surayyoxon Abdusamatovna, Sharofiddin Shaxobiddin o'g'li Abdullayev und Ibrohimjon Rahmonovich Asqarov. „CHILONJIYDA (ZIZIPHUS JUJUBA) O`SIMLIGINING KIMYOVIY TARKIBI VA SHIFOBAXSH XUSUSIYATLARI“. Журнал химии товаров и народной медицины 2, Nr. 1 (15.05.2023): 184–209. http://dx.doi.org/10.55475/jcgtm/vol2.iss1.2023.152.
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Chilonjiyda dorivor xususiyatlari bo`yicha qizilmiya, rehmanniya, jenshen, mumiyo, mirobolanlar kabi universal tabiiy dorivor manbalar qatoriga kiradi. Maqolada chilonjiyda o`simligining bargi va mevasining kimyoviy tarkibini o`rganish bu o`simlikdan gipertonik, yurak qon-tomir, o`pka, asab, allergik va saraton kabi kasalliklarni xalq tabobati usullarida davolash bo`yicha olib borilgan tadqiqotlarning qisqacha sharhi bayon etilgan.
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Аззамов, Юсуфжон. „Og‘zaki tarjima jarayonida tezlik va tempni o‘rgatish usullari“. Арабский язык в эпоху глобализации: инновационные подходы и методы обучения 1, Nr. 1 (24.12.2023): 206–9. http://dx.doi.org/10.47689/atgd:iyom-vol1-iss1-pp206-209-id28453.
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Maqolada tarjimonga urg'u berilgan holda talqin jarayonida tezlik va tempni o'rgatish usullari muhokama qilinadi. Tarjimaning murakkabligi psixologiya, adabiyot, etnografiya va tarix kabi turli fanlarni o'z ichiga olgan ko'p qirrali hodisa sifatida tan olinadi. Tarjima fanining turli jihatlarini hisobga olgan holda, zamonaviy tarjimashunoslikning muhim jihati bo'lgan lingvistik jihatlarga alohida e’tibor qaratilmoqda. Keyinchalik, dars va topshiriqlarning tezligiga alohida e'tibor qaratilib, tempni belgilashning asosiy turlari muhokama qilinadi. Dars tezligi tashkiliy analitiksoniyalarva tezkorxatolar muhokamasi orqali ta'kidlanadi. Magnitafonlar va kompyuterlar kabi texnologik vositalar potentsial buzilishlar sifatida qayd etilgan, bu esa ehtiyotkorlik bilan rejalashtirishni talab qiladi. Mashg'ulotning turli bosqichilarida yuqori tezlikka erishish usullari tavsifi bilan vazifani bajarish tezligi tushunchasi kiritiladi. Tarjima tezligini oshirish uchun raqobat va jamoaviy javobgarlik mexanizmlarini, shuningdek, raqamlar yoki so'zlarni takrorlash va zanjirli ish kabi aniq vazifalarni qo'llash taklifetiladi.
Dissertationen zum Thema "Kabi"
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Gorabi, Aline, und Maria Pless. „Visualisering av steriliseringsprocess på Fresenius Kabi“. Thesis, Uppsala universitet, Institutionen för informatik och media, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-362114.
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This study aims at investigating how a web application can be designed to visualize data in an efficient and useful manner. The study also aims at investigating which elements and methods of visualization contribute to understanding information that is visualized in the form of an interface. The question that the essay is about to answer is how a web application can be designed to visualize data in an efficient and useful way? To answer the question, a web application has been developed that visualizes data in the sterilization process. The research strategy used for the study is Design Science. Data collection and requirements have been collected through participatory observations in production at Fresenius Kabi. In order to create a web application that is useful and adapted to the environment it is intended for, Jakob Nielsen's usability principles, Stephen Few's design guidelines, Rick Borup’s theories and theory of web standards have been used as the basis for development. The web application and its usability have been evaluated using expert evaluations based on Steve Krug's guidelines as well as Jakob Nielsen's rating scale. The paper's discussion presents considerations and proposals for further research. The conclusion presented is that the development of a web application that emphasizes visualisation can be designed in a useful and clear manner by performing a thorough collection of requirements and well-performed expert evaluations with users. By reviewing previous research and theories related to usability and design, a visual representation of existing data can be a useful tool that can be used to optimize the production processes in the future.
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Rudra, Taraknath. „Kanta kabir jiban o kabyakriti কান্ত কবির জীবন ও কাব্যকৃতি“. Thesis, Calcutta University, 2002. http://hdl.handle.net/123456789/2124.
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Beetson, Bianca Renee. „Exploring Aboriginal identity through Self- portraiture“. Thesis, Griffith University, 2017. http://hdl.handle.net/10072/376769.
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This exegesis examines my practice through my identity as a Kabi Kabi, Wiradjuri, Kuku Ylandji and Pita Pita woman with English, Scottish and Romany Gypsy heritage. It contextualises the development of my practice from 1997 to 2017, which is the period immediately following my graduation from an undergraduate degree until now. The major focus of the exegesis, however, is on works from the last decade, when self-portraiture became a prominent part of my practice, which I explore through a variety of media: photography, performance, painting, drawing, and sculpture.
To contextualise my practice, I also examine contemporary artists who utilise Indigenous frameworks to disrupt the traditions of Western portraiture. My own work uses humour and ideas of performativity as tools to positively intervene into debates about Aboriginal identity. For example, my use of the colour pink can be understood as candy coating a difficult conversation around colonisation. I also reclaim the language of the coloniser through serial portraiture and challenge ideas of Aboriginal femininity. Contributing to identity politics art, I refuse the idea of an essential self through the idea of a performative self-portrait. One of my aims is to reclaim Aboriginal agency and to decolonise the idea of the self.Thesis (Professional Doctorate)
Doctor of Visual Arts (DVA)
Queensland College of Art
Arts, Education and Law
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Adhikari, Sudam Chandra. „Kabisekhar Kalidas Roy : Jibon O Kabyo কবিশেখর কালিদাস রায় : জীবন ও কাব্য“. Thesis, University of North Bengal, 1996. http://hdl.handle.net/123456789/1687.
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Bango, Nomasango Ida. „Assessing employee perceptions of quality at Fresenius Kabi Manufacturing South Africa (FKMSA)“. Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1019778.
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The pharmaceutical industry is one of the fastest growing and developing industries in the world today. With the ever advancing technology and manufacturing techniques, quality assurance has become the focus of regulatory bodies all over the world. The implementation of quality management systems (QMS) that ensures that quality is built into every step of the design and manufacturing process has been the focus of many pharmaceutical companies. With the implementation of quality systems, employee’s perception of those systems and overall quality standards of the organisation is very important in establishing the quality culture of the organisation. To benefit from sustainable quality systems the organisations must ensure that employees understand the importance of the systems and that employee’s take personal responsibility for ensuring that their functions are performed correctly the first time. FKMSA has invested in a QMS that seeks to integrate all quality issues. The quality system includes documentation, deviations, corrective and preventative action (CAPA), change controls and quality risk management (QRM) in the entire facility. This system is administered by the quality control department, but each department takes ownership for their quality issues with support and guidance from the quality unit. FKMSA also firmly believes that quality cannot merely rely on the quality control test results; every step of the production process has a quality aspect built in to ensure that quality standards are adhered to. Every employee is trained, assessed and deemed competent before they can perform their duties; this is to ensure that human errors are kept to a minimum. Employee’s perception of quality is an integral part of quality assurance and it is important for the organisation to know what the employees believe to be the company’s standards of quality.
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Mukherjee, Nabanita. „Kabi Jagajjiban Ghosaler manasamangal puthi sampadana, path bichar o kabya bislesan কবি জগজ্জীবন ঘোষালের মানাসমঙ্গল পুঁথি সম্পাদনা, পাঠ বিচার ও কাব্য বিশ্লেষণ“. Thesis, University of North Bengal, 2006. http://hdl.handle.net/123456789/1699.
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Barman, Tapati. „Adhunik Bangla Kabitay Nagar abong Nagarikata:Tinjan Bangla Kabi আধুনিক বাংলা কবিতায় নগর এবং নাগরিকতা : তিন জন বাংলা কবি“. Thesis, University of North Bengal, 1993. http://hdl.handle.net/123456789/1632.
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Ohldén, Mikael. „Effektivisering av destruktionsprocess : En förstudie om hur Fresenius Kabi kan effektivisera befintlig destruktionsprocess“. Thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176968.
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This thesis is a feasibility study into how Fresenius Kabi may rationalize their destruction process in regards to cost, recycling, and work environment. The two main objectives are to identify scrap flows and the possibility to improve or replace the equipment that is now carrying out the physical scrapping. The flow has been visualized by a flow chart of the material and communication. A chart of the problem established to visualize where improvements are necessary. Based on the problems proposals are presented on how to improve the flow thru the plant. During analyze of the physical scrapping equipment it was also necessary to take a deeper look at how they are carrying out there work today, how does the procedure look like, working environment and where are the weaknesses. On this basis, the problem where analyzed and suggestions for improvement were created. As today`s equipment is not effective enough a simplified specification established in order to more easily be able to design new equipment. A number of different solutions have been developed and eventually the two best was compared to visualize who fits best. Fresenius Kabi strives to achieve a high environmental awareness therefore this report also looks in to how they handle their waste today and if this is possible to improve it, especially with regards to the possibility to recycling the waste in the best way. Lean and Supply chain management has been used as a theoretical foundation for this report. This report resulted in proposals of how to change scrapping equipments, working environment and the flow of communication to achieve a more efficiency flow of material trough the plant.
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Frykfors, Alexis, und Philip Strand. „Sambandet mellan säkerhetskrav och höga lagernivåer inom läkemedelsbranschen : En fallstudie på Fresenius Kabi“. Thesis, Högskolan i Gävle, Industriell ekonomi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-24367.
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Background: An organization's ability to control bound material can be the difference between success or failure. Organizations that effectively work with supply chain management has strengthened their positions and increase their competitive edge on the global market. Organizations is the pharmaceutical industry has a major social responsibility by ensuring a continuous flow of medicines as well as pharmaceutical equipment. The industry is controlled by the strict regulations. The stringent security requirements for delivery reliability and delivery precision combined with extensive production regulations have resulted in these organizations having difficulty in maintaining even inventory levels. Purpose: The study aims to investigating the correlation between high level of safety requirements in the pharmaceutical industry and high inventory levels with the help of a case study. The study wants to investigate consequences of such connection as well investigate potential solution in which organizations can reduce their inventory levels without jeopardizing the delivery precision and delivery safety of pharmaceutical organizations. A case study has been conducted at the pharmaceutical company Fresenius Kabi who is a global market leader in the production of intravenous nutritional solutions. Finding: Findings of the study indicates that safety requirements controlling the pharmaceutical industry have a major impact on the organization's production planning and storage. The consequences of the high security requirements results in in uneven production patterns and tied capital in high inventory levels. The consequences also indicated on a Bullwhip-effect. Lean management enables organizations in the pharmaceutical industry to establish even production patterns and reduce their inventory levels. The study presents a new factor that prevents organizations in the pharmaceutical industry to reduce the number of articles. The new factor has a strong link to why organizations in the pharmaceutical industry have high inventory levels.Bakgrund: Hantering av lager och uppbundet material kan vara avgörande för en organisations framgång eller misslyckande. En ökad globalisering av dagens marknad har lett till att organisationer som effektivt arbetar med supply chain management stärker sina positioner och ökar sina konkurrensfördelar. En bransch på den globala marknaden som verkar under håra regleringar är läkemedelsbranschen. Branchen har ett stort samhällsansvar genom att säkerställa ett kontinuerligt flöde av läkemedel samt läkemedelsutrustning. De hårda säkerhetskraven på leveranssäkerhet och leveransprecision i kombination med omfattande produktionsregleringar har resulterat i att dessa organisationer har svårt att upprätthålla jämna lagernivåer. Syfte: Med hjälp av en fallstudie vill studien undersöka hur sambandet mellan höga säkerhetskrav och höga lagernivåer inom läkemedelsbranschen ser ut. Studien vill undersöka hur sambandet påverkar organisationer inom läkemedelsbranschen samt analysera hur man medhjälp av olika åtgärder kan minska lagernivåer utan att äventyra organisationernas leveransprecision och leveranssäkerhet. Fallstudien är baserad på läkemedelsorganisationen Fresenius Kabi. Fresenius Kabi är en global aktör som är marknadsledande inom produktion av intravenösa näringslösningar. Studien har undersökt produkten smofkabvien som produceras i Uppsala i syfte till att besvara studiens frågeställning. Med hjälp av intervjuer och insamlad sekundärdata besvaras studiens syfte. Slutsats: Studienkonstaterar att säkerhetskraven som reglerar läkemedelsbranschen har en stor inverkan på organisationens produktionsplanering och lagerhållning. Resultatet av de höga säkerhetskraven resulterar i ojämna beställning-och produktionsmönster vilket resulterar i hög kapitalbindning samt indikerar på en potentiell Bullwhip-effekt inom försörjningskedjan. Med hjälp av Lean management, heijunka och just-in-time kan organisationer inom läkemedelsbranschen upprätta jämna produktion-och beställningsmönster samt reducera sina lagernivåer. Studien presenterar en ny faktor vilken förhindrar organisationer inom läkemedelsbranschen möjlighet att reducera antalet artiklar. Den nya faktorn har en stark koppling till varför organisationer inom läkemedelsbranschen höga lagernivåer.
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Eminovic, Nejra, und Rana Tajik. „How to Improve a Planning System and Workflow in a Quality Control Laboratory : A Case Study at Fresenius Kabi in Sweden“. Thesis, KTH, Industriell ekonomi och organisation (Inst.), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-300149.
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Laboratories within quality control are very complicated to schedule due to the high product mix and diversified products tested with many different analysts and instruments. Thus, it requires a flexible planning system to change and improve the overall lab performance and increase efficiency. This thesis is a case study in collaboration with Fresenius Kabi AB and the quality control (QC) department in Uppsala. The QC department has an inflow of batches from the production department as well as from internal customers. Internal customers usually send batches that are part of stability studies or projects. These stability batches arrive at the QC department within irregular intervals and sometimes tightly adjacent, making the QC planning more complex, creating backlogs. Hence, the question in the study is formulated: ● How to improve a planning system and workflow in a quality control department? The current condition of batch inflow and how the planning system is managed today have to be understood to answer the question. Hence, the following sub-questions will be answered: ○ How is the current planning system at the quality control structured? ○ How is the inflow of stability batches at the department made more even andpredictable? This study aims to accomplish a practical planning system to prevent WIP, bottlenecks, and backlogs. The thesis is based on a qualitative method involving an inductive approach. The data collected mainly includes data from incoming batches, interviews, and literature studiesto gain multiple perspectives on the covered area. The study results showed that the internal customers were not satisfied with the current delivery times of QC. The common patterns identified are that internal customers want more contact and cooperation with the QC department. Furthermore, the result shows that the QC can handle the batches that arrive, but the planning system is not good enough. The proposed improvements to the current planning system are mainly to change it to a longer-term planning system and introduce a standard log or planning system between the internal departments. Also, QC should reorganize the lab and schedule based on common analysis to accomplish a higher efficiency of the scheduling. Further recommendations include more transparency and precise planning between departments to improve the inflow of the stability batches.Quality Control (QC) laboratorium är svåra att planera detta på grund den höga mängden och variationen av produkter. Det kräver således ett flexibelt planeringssystem för att förändra och förbättra prestandan och öka effektiviteten i laboratorier. Detta examensarbete är en fallstudie i samarbete med Fresenius Kabi AB och deras kvalitetsavdelningen i Uppsala. QC avdelningen har ett inflöde av batcher från produktionsavdelningen samt från de interna kunder. De interna kunderna skickar vanligtvis batcher som ingår i stabilitetsstudier eller projekt. Dessa stabilitets batchar inkommer till QC inom icke bestämda tidpunkter och ibland tätt inpå varandra, vilket försvårar planeringen inom QC vilket in sin tur skapar backloggar. Därav är frågeställningen i studien formulerad: ● Hur kan ett planeringssystem och arbetsflöde i ett kvalitetskontroll laboratoriumförbättras? För att kunna besvara denna frågeställning bör det aktuella planeringssystemet i avdelningen att undersökas. Därav kommer även dessa delfrågor att besvaras för att i denna studie: ● Hur är det nuvarande planeringssystemet strukturerat? ● Hur kan inflödet av stabilitets studier på avdelningen jämnas ut och bli mer förutsägbara? Syftet med denna studie är därav att effektivisera det nuvarande planeringssystem för att förhindra WIP, flaskhalsar och backlogs i QC avdelningen. Examensarbetet bygger på en kvalitativ metod med en induktiv forskningsansats. Den insamlade datan främst inkluderar data från inkommande batcher, intervjuer samt litteraturstudie för att få flera perspektiv av det undersökta ämnesområdet. Studiens resultat visade att samtliga interna kunder inte är nöjda med de nuvarande leveranstider som QC har. De gemensamma mönster som identifierats är att de interna kunderna önskar mer kontakt och samarbete med QC avdelningen. Vidare visar resultatet att QC bör ha kapaciteten som krävs för att kunna hanterade batcher som inkommer men att planeringen inte är tillräckligt bra. De förbättringsförslag som föreslås till det nuvarande planeringssystemet är främst att utveckla en mer långsiktig planering samt införa en gemensam logg. QC avdelningen på Fresenius Kabi bör även se över sin organisering och dela in grupper baserat på analyser och inte utrustning. Vidare rekommendationer inkluderar mer transparent och tydlig planering mellan avdelningarna.
Bücher zum Thema "Kabi"
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Mukhopādhyāẏa, Dhrubakumāra. Kabi ebaṃ kabi. Kalakātā: Karuṇāmaẏī, 2007.
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Ghosha, Manmathanātha. Kabi Bihārīlāla o kabi Īśānacandra. Kalakātā: Pustaka Bipaṇi, 2005.
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Bandopadhyay, Tarashankar. Kabi. Calculla: Mitra & Ghosh, 1993.
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Calihā, Saurabha Kumāra. Kabi. Guwāhāṭī: Banalatā, 1999.
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Calihā, Saurabha Kumāra. Kabi. Guwāhāṭī: Banalatā, 1999.
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Āhameda, Humāẏūna. Kabi. Ḍhākā: Kākalī Prakāśanī, 1996.
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Nanda, Saudāminī. Kabi kaḷpa. Kaṭaka: Āryya Prakāśana, 1997.
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Mukhopādhyāẏa, Bāsantīkumāra. Mahāgodhūlira kabi. Kalikātā: Bāk-Sāhitya, 1999.
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Sārbabhauma kabi. Ḍhākā: Mallika Brādārsa, 1990.
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Subrata, Gaṅgopādhyāẏa, Hrsg. Kabi Nīrendranātha. Kalakātā: Antarīpa, 1992.
Den vollen Inhalt der Quelle findenBuchteile zum Thema "Kabi"
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O’Chin, Hope. „Kabi-Kabi Genre in Art and Education Pedagogy“. In An Epistemology of Belongingness, 137–48. Cham: Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-32288-4_7.
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Naumann, Nelly. „Tokuda Shūsei: Kabi“. In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_21249-1.
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Prill, Susan. „Kabir“. In Encyclopedia of Scientific Dating Methods, 209–11. Dordrecht: Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-024-0846-1_499.
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Kose, Ali. „Kabir“. In Encyclopedia of Psychology and Religion, 1314–15. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-24348-7_371.
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Ziolkowski, Mari P. „Kali“. In Encyclopedia of Psychology and Religion, 1315–18. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-24348-7_9104.
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McDaniel, June. „Kali“. In Hinduism and Tribal Religions, 1–4. Dordrecht: Springer Netherlands, 2018. http://dx.doi.org/10.1007/978-94-024-1036-5_221-1.
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Kose, Ali. „Kabir“. In Encyclopedia of Psychology and Religion, 986–87. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-1-4614-6086-2_371.
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Ziolkowski, Mari P. „Kali“. In Encyclopedia of Psychology and Religion, 987–90. Boston, MA: Springer US, 2014. http://dx.doi.org/10.1007/978-1-4614-6086-2_9104.
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Ayten, Ali, Jeffrey B. Pettis, Ali Kose, Paul Larson, Tadd Ruetenik, Marta Green, Paul C. Cooper, Joenine E. Roberts und Carol L. Schnabl Schweitzer. „Kabir“. In Encyclopedia of Psychology and Religion, 498–99. Boston, MA: Springer US, 2010. http://dx.doi.org/10.1007/978-0-387-71802-6_371.
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McDaniel, June. „Kali“. In Hinduism and Tribal Religions, 728–32. Dordrecht: Springer Netherlands, 2022. http://dx.doi.org/10.1007/978-94-024-1188-1_221.
Der volle Inhalt der QuelleKonferenzberichte zum Thema "Kabi"
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Agnelli, G., J. Born, I. Cosmi, M. Levi und J. W. ten Cate. „EFFECTS OF STANDARD HEPARIN AND A LOW MOLECULAR WEIGHT HEPARIN (KABI 2165) ON PLASMA LEVEL OF t-PA AND PA INHIBITOR“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642867.
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Previous and recent reports have suggested a fibrinolysis-enhancing property of standard heparin (SH) and low molecular weight heparin (LMWH) but these observations have never been confirmed in a clinical study fulfilling appropriate methodological criteria.Aim of this study was to evaluate in a cross-over double blind placebo-controlled study the effect of SH and LMWH (K 2165) on fibrinolysis. Six healthy volunteers (age 22-30) received a bolus dose of the following treatments: l)Placebo, 2)Kabi SH,5000 I.U., 3) Kabi 2165,5000 anti Xa U, 4)Kabi 2165, 10000 anti Xa U. A 4 day wash-out period was adopted.The volunteers had been fasting for at least 12 hours before the infusion and were sitting during the experiment.Before starting the infusion and at 1,2,5,10,15,30,60,120 minutes thereafter, blood samples were collected for the assay of t-PA activity, PA inhibitor activity, plasminogen, alfa2-antiplasmin, fibrinplate lysis area (FPLA), fibrinogen, aPTT, antithrombin III and anti-Xa activity. Placebo and Kabi 2165,5000 U had no effect on t-PA plasma level, however both SH and Kabi 2165,10000 U produced a statistically significant increase of t-PA level at 1 hour after the infusion. The t-PA increase lasted for at least 2 hours after the infusion; at that time the average t-PA activity was 0.14 U/ml for SH and 0.09 U/ml for Kabi 2165,10000 U (p<0.05, AN0VA,average pre-infusion level and placebo at 2 hours:0.01 U/ml).At that time plasma anti-Xa was 0.11 U/ml for SH and 1.05 U/ml for Kabi 2165,10000 U. SH and Kabi,10000 produced no effect on PA inhibitor.No effect of any treatment on fibrinogen,alfa2-antiplasmin,plasminogen, FPLA and antithrombin III was observed. We conclude that in this study both SH and Kabi 2165 produced a delayed and sustained increase of t-PA. The relevance of this effect remains to be established.
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Prins, M. H., G. J. H. den Ottolander, R. Gelsema, T. C. M. van Woerkom, A. K. Sing und I. Heller. „DEEP VENOUS THROMBOSIS PR0FYLAXIS WITH A LMW HEPARIN (KABI 2165) IN STROKE PATIENTS“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643217.
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In a group of 60 patients entering our hospital for completed stroke, within 72 hours after onset of symptoms, treatment with Kabi 2165 2x 2500 anti-Xa U s.c. was compared to placebo 2x s.c. in a double blind trial to test the assumption that Kabi 2165 could prevent DVT, without causing cerebral bleeding in the ischaemic area. The diagnosis of stroke was made on clinical grounds. A.CT-scan of the head was performed before entering the trial to exclude cerebral bleeding or tumor. Follow-up during a trial period of 14 days included a Fibrinogen scan - if positive followed by flebografy. After the trial period or when clinical deterioration occurred a CT-scan of the head was repeated. Before and during the trial period haematologic and coagulation data were obtained and will be reported. Obduction was obtained whenever possible.The patient groups were comparable, except for a slight preponderance of disturbed consciousness and atrial fibrillation in the Kabi 2165-treated group. This difference did not reach statistic significance. In the Kabi 2165 group there were 6 cases of DVT compared to 15 in the placebo group (p=0,05). In the Kabi 2165-treated group there were slightly more cases of cerebral bleeding and death during trial, respectively 4 versus 2 and 9 versus 4 (both NS). Cerebral bleeding occurred only in patients with a bloodpressure above 150/90 mmHg on entering.Although the patient group is still small, we like to conclude that in normotensive stroke patients Kabi 2165 2x 2500 anti-Xa U s.c. per 24 hours, is a safe method of DVT profylaxis.
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Potron, G., J. Barre, C. Droulle, J. C. Baudrillard, P. Barbie und A. Kher. „THROMBOSIS PROPHYLAXIS WITH LOW MOLECULAR WEIGHT HEPARIN (KABI 2165) AND CALCIUM HEPARIN IN PATIENTS WITH TOTAL HIP REPLACEMENT“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643220.
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In a prospective controlled randomized trial efficacy and safety of a low molecular weight heparin (Kabi 2165) and calcium heparin were compared in 80 patients with total hip replacement. 40 patients were given Kabi 2165 : 2,500 anti-Xa Units S.C. 2 hours before operation and then every 12 hours for 10 days. 40 patients received calcium heparin : 5,000 iu S.C. 2 hours before operation, then every 8 hours during the first post operative day and then heparin doses were adjusted according to the activated partial thromboplastin time and the thrombin time for 10 days. Bilateral venography was performed routinely on all patients between the ninth and tenth post operative day. The two groups were well matched for risk factors which could predispose to risk of developing venous thrombosis. 7 patients in Kabi 2165 group (17,5 96) and 4 patients in calcium heparin group (10 %) developed D.V.T. (p = 0.33). In 3 patients (7,5 96) of Kabi 2165 group and in 2 patients (5 96) of calcium heparin group, the thrombi extented to the popliteal-femoral vein. The incidence is not significantly different (p = 0,50). There were no significant differences in postoperative mean estimated blood losses, and mean blood units transfused. Mean hemoglobin levels and mean hematocrit values at the day before operation, the 1st, 5th, and 10th day after operation were :These differences were not statistically significant. Incidence of wound hematomas was similar in both groups No thrombocytopenia was reported in this study. In conclusion, Kabi 2165 2,500 anti Xa Units twice daily seems as efficient as adjusted-dose of calcium heparin thrice daily.
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„A RANDOMIZED, DOUBLE BLIND STUDY OF A LOW MOLECULAR WEIGHT HEPARIN (KABI 2165) ONCE DAILY AND LOW DOSE STANDARD HEPARIN TWICE DAILY, IN THE PREVENTION OF POST OPERATIVE DEEP VEIN THROMBOSIS IN GENERAL SURGERY. A French Multicenter Trial“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643594.
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The efficacy and safety of a low molecular weight heparin (Kabi 2165) in preventing postoperative deep vein thrombosis (D.V.T.), was assessed in a double blind randomly allocated multicenter trial. 385 patients were included and analysed on a intention to treat basis. Kabi 2165 was given S.C. 24 hourly in 2 500 anti-factor Xa units and compared with standard low dose calcium heparin 5 000 i.u. S.C. 12 hourly in patients undergoing major abdominal or gynaecological surgery. The first dose was administered two hours before operation in both groups. The relevant characteristics of the patients in the two treatment groups were similar. The two groups were well matched for risk factors which could predispose to D.V.T.DVT was detected by the radioactive fibrinogen test. Venography was performed whenever a positive scan developed in a patient. Six (3,1 96) of 195 patients receiving Kabi 2165 and seven (3,7 96) of 190 patients in the standard heparin group developed D.V.T. No pulmonary embolism we re detected during the prophylactic regimens. There was no significant difference between the two groups in terms of blood loss during surgery, postoperative drainage, blood transfusion, wound haematoma. Mean hemoglobin levels and mean hematocrit values preoperatively and postoperatively (day 1 and 6) were :There were no statistically significant differences in both groups. No thrombocytopenia was reported in this study. The antifactor Xa activity was significantly higher in the Kabi 2165 group.In conclusion, Kabi 2165 once daily is as effective and safe as standard heparin twice daily in preventing postoperative D.V.T. in general surgery.
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Mammen, E. F., A. M. Farag, R. J. Sachs und J. M. Brown. „ANTITHROMBIN III, PLASMINOGEN, α2 ANTIPLASMIN, PREKALLIKREIN AND HEPARIN ASSAYS ON AN AUTOMATED COAGULATION LABORATORY (ACL 810) ANALYZER“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643254.
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A recently introduced automated, microcomputer controlled centrifugal analyzer ACL 810 (Instrumentation Laboratories, IL) performs both clot based and chromogenic substrate based assays. We compared the performance characteristics of this new instrument with the Multistat III Centrifugal Analyzer (MCA, Instrumentation Laboratories) and the Protopath system (American Dade). Antithrombin III (AT) and plasminogen (PLG) were assayed on the ACL 810 using II kits, on the MCA using Kabi kits, S-2238 and S-2251, and on the protopath Dade reagents. 02 Antiplasmin (AP) was determined on the ACL with kits from General Diagnostics and on the MCA with the Kabi kits S-2251. On the protopath we used Dade reagents. Prekallikrein (PK) was analyzed on the ACL and MCA using Kabi kits S-2302. We adapted the plasminogen channel of the ACL for this assay. The correlation data for these four assays were as follows:AT and PLG assays on the ACL using Kabi kits correlated equally high.We also compared heparin assays, both anti IIa and anti Xa, on the ACL (anti IIa, II kits, anti Xa, Stago kits) with the MCA (anti Xa) and a spectrophotometer (anti IIa). The data are summarized below:These data suggest excellent correlations between the new ACL 810 and other instruments for these assays.
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Li, Caixia, Wenhua Xu, Xizhu Si und Ping Song. „KABI: Class-Incremental Learning via knowledge Amalgamation and Batch Identification“. In ICIAI 2021: 2021 the 5th International Conference on Innovation in Artificial Intelligence. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3461353.3461367.
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Graunebaum, L., J.-P. Fricker, M.-L. Wiesel, Y. Vergnes, J.-P. Cazenave, P. Barbier und A. Kher. „EFFICACY AND SAFETY OF A LOW MOLECULAR WEIGHT HEPARIN (L M W H KABI 2165) IN PROPHYLAXIS OF POSTOPERATIVE DEEP VEIN THROMBOSIS (D.V.T.) AFTER ONCOLOGICAL SURGERY“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643219.
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The effect of a LMWH - Kabi 2165 on thrombo-embolism prophylaxis was studied in a prospective, randomized trial of 74 patients scheduled for surgery due to malignant diseases. 38 patients received 2 500 anti-Xa units S.C. 2 hours before operation, then 12 hours after and then 5 000 anti-Xa units once a day for 10 days. 36 patients were given calcium heparin 5 000 i.u S.C. 2 hours before operation and then three time a day for 10 days. 125I-Fibrinogen uptake test was used in all patients to detect D.V.T. Positive scan was controlled by phlebography. In the Kabi 2165 group, 2 patients had positive scan not confirmed by phlebography No pulmonary embolism was reported. In the calcium heparin group, 2 patients developed non fatal pulmonary embolism. The fibrinogen test was negative in all the patients. Intra and postoperative blood loss, transfusion requirements, wound hematomas and infectious complications did not differ significantly between the two groups. The mean values of hematocrit and hemoglobin preoperatively and post operatively (day 1, and 10) were similar for the two groups :It is concluded that a single daily injection of 5 000 anti-Xa units of Kabi 2165 may provide a prophylaxis against postoperative venous thromboembolism as effective and as safe as 3 daily injections of 5 000 i.u. of calcium heparin in oncological surgery.
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Potron, G., O. Toupance, C. Droulle, J. Chanard, A. Kher und P. Barbier. „USE OF A LOW MOLECULAR WEIGHT HEPARIN (LMWH) KABI 2165 DURING HAEMODIALYSIS : DETERMINATION OF LOWEST EFFECTIVE DOSE-MEMBRANE DEPENDANT DOSAGE REGIMEN“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643221.
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The L.M.W.H., Kabi 2165 was compared to standard heparin in stable chronic haemodialysis patients in order to determine the lowest effective dose.An initial dose of 1,000 to 2,500 anti-Xa units followed by an additional dose of 750 to 1,500 anti-Xa units, 1 or 2 hours after the start of the c’alysis was associated with clotting and bleeding complications on 156 dialysis performed in 8 patients: 33 partial coagulations of extracorporeal circulation and 16 minor bleeding events. This dosage regimen corresponds to half of that of standard heparin needed in the same patients to prevent clinical problems.In 9 patients treated with haemodialysis for 4 hours or less using cuprophane membrane, a single dose of 80 anti-Xa units/kg given at the start of dialysis achieved a sufficient antithrombotic effect on 195 dialysis, but minor bleeding complications were observed in 4 cases.On 270 dialysis perfomed in 12 patients using polyacrylonitrile membrane, it was necessary to increase by 1,000 anti-Xa units this previous dosage to obtain satisfactory effectiveness.The biological activities measured in this study indicates that : rises in fibrinopeptide A and platelet factor 4 were associated with clotting in the extracorporeal circulation.Increased levels of factors VIII : RAg and decreased levels of prekal1ierein in the predialysis blood sanples were corrected by Kabi 2165.In conclusion, Kabi 2165 would appear to be an effective and easier antithrombotic agent in patients on chronic haemodialysis.
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Filippi, J. F., D. Arnoux, N. Tubiana, B. Boutière, F. Le Caär, J. Sampol, Lab Hématol, Pr J. Sampol und Pr Y. Carcassonne. „PLASMINOGEN ACTIVATOR ACTIVITY OF NORMAL AND MALIGNANT MONONUCLEAR HUMAN CELLS“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643167.
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Plasminogen activators (PA) are thought to play a role in the invasive and metastatic properties of many types of cancer cells. Though, discrepancies in correlations between fibrinolytic activity and metastatic potential of malignant cells have been described.In this study, we evaluated both tissue type (tPA) and urokinase type (UK) cellular PA activities in different mononuclear cell types : normal T and B human peripheral lymphocytes, B cells from patients with chronic lymphocytic leukemia (CLL), human blood monocytes, alveolar macrophages, U 937, RAJI and JM cell 1ines.Mononuclear cells were isolated by Ficoll-hypaque gradients and monocytes by plastic adhesion. T and B cells were separated by a rosetting technique using sheep red blood cells. Cellular extracts were prepared by 0.5 % Triton X 100 buffer treatment followed by sonication and centrifugation 10 ' at 2000 g. PA assays were performed on the supernatants.UK-type PA was evaluated by a liquid-phase assay in presence of human plasminogen (Kabi) and chromogenic substrate S 2251 (Kabi).tPA was determinated using a solid-phase fibrin activity assay which involves an affinity separation step and thus allows selective detection of tPA.In both cases, results were reported in international units by reference to standard curves of UK (Choay) or tPA (Kabi).In all cell types tested, PA detected was essentially urokinase-type. Highest PA activity was found in U 937 cells (0.7 IU/5×l06 cells). In normal blood lymphocytes, mean PA activity was 0.08 IU/5×l06 cells. Examination of lymphocytes from patients with CLL revealed a marked decrease in UK activity as compared to normals (< 0.01 IU/5×106 cells in more than 50 % cases).The function of PA in normal lymphocyte physiology and the potential pathogenic role of diminished PA in CLL lymphocytes remains to be investigated.
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Racanelli, A., und J. Fareed. „DIFFERENTIAL NEUTRALIZATION OF UNFRACTIONATED HEPARIN (UH) AND LOW MOLECULAR WEIGHT HEPARINS (LMWHS) BY HUMAN PLATELET FACTOR FOUR (PF-4)“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643502.
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Platelet factor 4 neutralization profiles of four newly developed LMWHs, PK 10169 (Pharmuka, Gennevilliers, France) CY 216 (Choay, Paris, France), KABI 2165 (KabiVitrum, Stockholm, Sweden), OP 2123 (Opocrin, Corlo Italy) and an unfractionated porcine mucosal heparin were studied utilizing amidolytic (anti-factor Xa, anti-factor Ila) and clot based (APTT, Heptest ) assays. The neutralization studies were carried out in normal human pooled plasma in two experimental protocolsIn one set of experiments, PF-4 (10μg/ml) was added to varying amounts of UH or LMWH (10-2.5 μg/ml). In the second set of experiments, the concentration of heparins was fixed at 5 μg/ml and varying amounts of PF-4(10-2.5 μg/ml) were added. The relative neutralization profiles of these heparins were assay dependant. The anticoagulant effects of UH and LMWHs as measured by APTT were equally neutralizable. Similarly the anti-factor Ila actions of both UH and LMWH were effectively neutralized, whereas the anti-factor Xa activity of the LMWHs was less neutralizable than the UH. Different levels of residual anti-Xa activity of the LMWHs were seen whereas the UH was effectively neutralized. Interestingly, although the anti Xa activity of the UH and Kabi 2165 as measured by amidolytic and clot based methods were similiar and more potent than the other LMWHs, however there were differences between their PF-4 neutralization profile. At a gravimetric ratio of 2:1 , the anti Xa activity of the UH was completely neutralized whereas the Kabi 2165 was least neutralized of all of the LMWHs. The slope of the PF-4 titration curves in the anti-factor Xa assays for all of the LMWHs were similar and varied significantly from the UH. PF-4 neutralization of UH and LMWHs was not dependant on the molecular weight or pharmacopoeial potency (USP or antifactor Xa). These results show that UH and LMWHs exhibit a dissociation between the anti-factor Xa and anti-factor Ila neutralization which may contribute to their sustained antithrombotic effects.
Berichte der Organisationen zum Thema "Kabi"
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Diprose, Rachael, Amalinda Savirani, Annisa Sabrina Hartoto und Ken M. P. Setiawan. Jalan Perubahan melalui Aksi Kolektif Perempuan Perdesaan: Upaya Perempuan dalam Menantang Arus untuk Memengaruhi Pembangunan Perdesaan di Indonesia. University of Melbourne with Universitas Gadjah Mada and MAMPU, 2020. http://dx.doi.org/10.46580/124330.
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Ikhtisar dari volume ini disusun untuk mengeksplorasi secara ringkas poin-poin utama yang dipaparkan di dalam studi kasus yakni bagaimana aksi kolektif perempuan telah membawa perubahan baik bagi kesejahteraan diri perempuan, maupun dampaknya bagi pelaksanaan Undang-Undang Desa di Indonesia, serta bagaimana perubahan-perubahan tersebut terwujud dengan dukungan berbagai organisasi masyarakat sipil dalam lintas konteks dan sektor. Pertama, kami mengidentifikasi perbedaan dan keberagaman prioritas dan inisiatif pembangunan desa sebagai hasil pengaruh keterlibatan perempuan dalam pelaksanaan UndangUndang Desa. Inisiatif pembangunan tersebut tidak hanya terkait isu infrastruktur dan ekonomi (walaupun perempuan juga telah mengupayakan beberapa inisiatif di isu ini), namun juga meliputi berbagai permasalahan pembangunan desa dan tantangan sektoral lain yang dihadapi oleh masyarakat desa, khususnya perempuan. Kedua, kami menjabarkan berbagai bentuk perubahan yang berdampak pada kesejahteraan sehari-hari perempuan, dan juga pengaruhnya pada struktur kuasa, pembuatan keputusan dan prioritas pembangunan, baik di tingkat desa, masyarakat, institusi, maupun konteks yang lebih luas. Ketiga, kami membahas proses yang mendasari perubahan, dan faktor-faktor yang berkontribusi terhadapnya, sebagaimana yang digambarkan melalui studi kasus yang ada. Ini termasuk pembahasan bagaimana dinamika konteks menghambat atau mendorong pengaruh perempuan, perbedaan dari isu dan tantangan sektoral yang dihadapi oleh perempuan, dan bagaimana aksi kolektif perempuan berkontribusi terhadap perubahan yang ada. Keempat, kami mengeksplorasi dimensi temporal dari perubahan tersebut. Terakhir, kami mengeksplorasi beberapa jalur atau jalan perubahan yang terjadi di lokasi penelitian, yang bervariasi sesuai dengan konteks lokal.
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Diprose, Rachael, Amalinda Savirani, Annisa Sabrina Hartoto und Ken M. P. Setiawan. Jalan Perubahan melalui Aksi Kolektif Perempuan Perdesaan: Upaya Perempuan dalam Menantang Arus untuk Memengaruhi Pembangunan Perdesaan di Indonesia. University of Melbourne with Universitas Gadjah Mada and MAMPU, 2020. http://dx.doi.org/10.46580/124330.
Der volle Inhalt der QuelleAnnotation:
Ikhtisar dari volume ini disusun untuk mengeksplorasi secara ringkas poin-poin utama yang dipaparkan di dalam studi kasus yakni bagaimana aksi kolektif perempuan telah membawa perubahan baik bagi kesejahteraan diri perempuan, maupun dampaknya bagi pelaksanaan Undang-Undang Desa di Indonesia, serta bagaimana perubahan-perubahan tersebut terwujud dengan dukungan berbagai organisasi masyarakat sipil dalam lintas konteks dan sektor. Pertama, kami mengidentifikasi perbedaan dan keberagaman prioritas dan inisiatif pembangunan desa sebagai hasil pengaruh keterlibatan perempuan dalam pelaksanaan UndangUndang Desa. Inisiatif pembangunan tersebut tidak hanya terkait isu infrastruktur dan ekonomi (walaupun perempuan juga telah mengupayakan beberapa inisiatif di isu ini), namun juga meliputi berbagai permasalahan pembangunan desa dan tantangan sektoral lain yang dihadapi oleh masyarakat desa, khususnya perempuan. Kedua, kami menjabarkan berbagai bentuk perubahan yang berdampak pada kesejahteraan sehari-hari perempuan, dan juga pengaruhnya pada struktur kuasa, pembuatan keputusan dan prioritas pembangunan, baik di tingkat desa, masyarakat, institusi, maupun konteks yang lebih luas. Ketiga, kami membahas proses yang mendasari perubahan, dan faktor-faktor yang berkontribusi terhadapnya, sebagaimana yang digambarkan melalui studi kasus yang ada. Ini termasuk pembahasan bagaimana dinamika konteks menghambat atau mendorong pengaruh perempuan, perbedaan dari isu dan tantangan sektoral yang dihadapi oleh perempuan, dan bagaimana aksi kolektif perempuan berkontribusi terhadap perubahan yang ada. Keempat, kami mengeksplorasi dimensi temporal dari perubahan tersebut. Terakhir, kami mengeksplorasi beberapa jalur atau jalan perubahan yang terjadi di lokasi penelitian, yang bervariasi sesuai dengan konteks lokal.
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Widianto, D. Suprayogo, Sudarto und I. D. Lestariningsih. Implementasi Kaji Cepat Hidrologi (RHA) di Hulu DAS Brantas, Jawa Timu. World Agroforestry Centre (ICRAF), 2010. http://dx.doi.org/10.5716/wp10338.pdf.
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Dutra, Lauren M., Matthew C. Farrelly, Brian Bradfield, Jamie Ridenhour und Jamie Guillory. Modeling the Probability of Fraud in Social Media in a National Cannabis Survey. RTI Press, September 2021. http://dx.doi.org/10.3768/rtipress.2021.mr.0046.2109.
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Cannabis legalization has spread rapidly in the United States. Although national surveys provide robust information on the prevalence of cannabis use, cannabis disorders, and related outcomes, information on knowledge, attitudes, and beliefs (KABs) about cannabis is lacking. To inform the relationship between cannabis legalization and cannabis-related KABs, RTI International launched the National Cannabis Climate Survey (NCCS) in 2016. The survey sampled US residents 18 years or older via mail (n = 2,102), mail-to-web (n = 1,046), and two social media data collections (n = 11,957). This report outlines two techniques that we used to problem-solve several challenges with the resulting data: (1) developing a model for detecting fraudulent cases in social media completes after standard fraud detection measures were insufficient and (2) designing a weighting scheme to pool multiple probability and nonprobability samples. We also describe our approach for validating the pooled dataset. The fraud prevention and detection processes, predictive model of fraud, and the methods used to weight the probability and nonprobability samples can be applied to current and future complex data collections and analysis of existing datasets.
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K., Khasanah, Mulyoutami E., Ekadinata A., Asmawan T., Tanika L., Said Z., van Noordwijk M. und Leimona B. Kaji cepat hidrologi di Daerah Aliran Sungai Krueng Peusangan, NAD, Sumatra. Working paper no.122. World Agroforestry Centre (ICRAF), 2010. http://dx.doi.org/10.5716/wp10337.pdf.
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K., Khasanah, Mulyoutami E., Ekadinata A., Asmawan T., Tanika L., Said Z., van Noordwijk M. und Leimona B. Kaji cepat hidrologi di Daerah Aliran Sungai Krueng Peusangan, NAD, Sumatra. Working paper no.122. World Agroforestry Centre (ICRAF), 2011. http://dx.doi.org/10.5716/wp11077.pdf.
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Bhalla, Kavi, und Esteban Diez-Roux. Cost of Traffic Injuries in Latin America. Inter-American Development Bank, Juni 2012. http://dx.doi.org/10.18235/0006934.
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This presentation was given by Esteban Diez-Roux and Kavi Bahlla at the Ibero-American Road Safety Conference (CISEV) which took place in Bogota, Colombia in June, 2012. This presentation describes how the high rate of traffic accidents in Latin America places a burden on economies in the region. The authors present the methods and results of a study which assigns a monetary cost to these deaths and injuries as a percent of GDP. The presentation ends with conclusions and implications.
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Kolovich, Rosenfeld und Richie. PR-218-104507-R01 Improved Methods for Estimating Remaining Fatigue Life of ERW Pipelines. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), April 2012. http://dx.doi.org/10.55274/r0010759.
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This report describes in full detail the calculations used by KAI in its software product PIPELIFE which is used to calculate fatigue crack-growth life. The results of analyses performed for standard benchmark cases supplied by PRCI were reported for comparison with the results obtained by other practitioners participating in the exercise. Preliminary comparisons of those results indicated that KAI�s results were in good agreement with those obtained by other participants. A more-thorough comparison of the results presented herein identified the apparent differences in the calculations. Several potential factors that could be further investigated for refining the calculations were considered. It is likely that some of them could have important influences, if the effects could be accounted for correctly. However, of those that may be significant, insufficient data exists to enable a user to accurately and reliably implement them. Performing an analysis predicated on an assumption that certain effects, such as retardation or thresholds, are operative when in fact they are not to the extent assumed could lead to results that are nonconservative, and subsequently to poor integrity management choices. Thus KAI recommends that either (a) further, and probably costly, research be conducted to better define under what circumstances such refinements are or are not appropriate, or (b) the present conservative approach continue to be followed for the time being. This project also investigated whether it is feasible to rely on pipe mill nondestructive examination to define pipe initial quality for purposes of establishing initial flaw size to calculate fatigue life. This could provide significantly longer predicted times to failure than those obtained where the commissioning hydrostatic test is the measure of pipe initial quality. It was determined that this could be reasonable for pipe manufactured after 1968 when API 5L imposed both length and depth limits on NDE reference standards. Prior to that time such a strategy would not be conservative. Between 1963 and 1968, such a strategy could be acceptable with knowledge that no hydrostatic test failure occurred. The non-occurrence of test failures suggests that pipe manufacturers were imposing NDE standards.
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Matt, Nyman. Evaluation of Students’ Response to Field Trips to HJ Andrews Experimental Forest. Oregon State University, September 2023. http://dx.doi.org/10.5399/osu/1162.
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The Andrews Forest Long-Term Ecological Research (LTER) site has a long-term partnership with the University of Oregon Environmental Leadership Program (ELP), providing service-learning opportunities for undergraduate students to facilitate field trips for middle school students to the Andrews LTER site. Undergraduate students develop field trip lessons based on Andrews Forest research and creative inquiry with support of Schoolyard LTER coordinator and Andrews LTER scientist Schulze. In Middle school students hiking in the Andrews LTER 2023, six classes and 156 students total engaged in day-long field trips at the Andrews LTER site that involved forest ecology and tree identification, time to reflect on and connect with the iconic old-growth ecosystems, and discussions about environmental stewardship ideas that the students could implement both at the Andrews LTER site and in their homes. The students came from three different schools, two of them rural schools with low socio-economic status in the Lane County Educational Service District and the other a Montessori school in the Eugene area. This report shares the results from an evaluation project led by Dr. Matt Nyman and Dr. Kari O’Connell that assessed the impact of the field trips on the middle school students. The evaluation was designed to also support the middle school students’ own reflection and learning at the same time as gathering data about the impact of the experience.
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Nevanlinna, Heikki, Tapani Kivinen, Jussi Paatero, Mirjam Kellinsalmi, Tiera Laitinen, Yrjö Kivinen, Tuulia Hongisto, Meri Pajunpää und Pyry Pajunpää. Nurmijärven geofysiikan observatorio 70 vuotta 1952–2022. Finnish Meteorological Institute, Juni 2023. http://dx.doi.org/10.35614/isbn.9789523361768.
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Ilmatieteen laitoksen Nurmijärven geofysiikan observatorio aloitti toimintansa syksyllä 1952. Observatorion päätehtävä oli ylläpitää jatkuvia magneettisia rekisteröintejä muualla Suomessa tehtävien magneettisten kartoitustöiden tueksi. Ilmatieteen laitoksen johdolla tehty magneettinen kartoitustyö saatiin päätökseen vuonna 1930, mutta yli kaksikymmentä vuotta myöhemmin tarvittiin magneettisen kartta-aineiston päivitys. Työhön saatiin Sodankylän geofysiikan observatorion johtaja Eyvind Sucksdorff (1899–1955) vuonna 1945. Sucksdorff oli jättänyt Sodankylän observatorion sen tuhouduttua Lapin sodassa 1944. Hänet nimitettiin Ilmatieteen laitoksen geofyysikon virkaan. Eyvind Sucksdorff aloitti kartoitustyöhön tarvittavat magneettiset maastomittaukset vuonna 1946 ja samaan alkoi myös Nurmijärven observatorion suunnittelu. Observatorion havaintorakennukset saatiin valmiiksi 1951 ja ensimmäinen kokonainen havaintovuosi oli 1953. Magneettisten rekisteröintien ohella observatorio oli Ilmatieteen laitoksen sääasema. Eyvind Sucksdorffin työt magnetismin alalla jäivät kesken, kun hän kuoli yllättäen vuonna 1955. Töiden jatkajaksi tuli Eyvindin poika Christian (1928–2016). Nurmijärven observatorion havaintojen ylläpito saatiin vakinaisemmalle kannalle, kun observatorioon saatiin pysyvää henkilökuntaa ja päärakennus toimisto- ja asuintilaksi. Observatorion paikallisjohtajaksi nimitettiin FM Matti Kivinen (1924–2010) vuonna 1957. Hänen johtajakautensa kesti vuoteen 1988 saakka. Kivisen jälkeen observatorion johtajuutta hoiti FT Kari Pajunpää (1956–2022) vuoteen 2018 saakka. Kansainvälisen Geofysiikan vuoden (IGY, 1957–1958) aikana Nurmijärven observatorion havaintotoiminta laajeni, kun sinne perustettiin Posti- ja lennätinhallituksen ionosondi ionosfäärin luotauksiin kaukomaille suunnattujen radiolähetyksien tueksi. Luotaukset jatkuivat vuoteen 1987 saakka. Vuonna 1961 Helsingin yliopisto perusti observatorion alueelle seismologisen havaintoaseman osana maailmanlaajuista maanjäristyksien havaintoverkkoa. IGY:n aikana Ilmatieteen laitos käynnisti revontulien valokuvausrekisteröinnit usealla asemalla Lapissa. Revontulikuvaukset jatkuvat edelleen uudemman sukupolven kameroilla. Vuonna 1959 observatoriossa aloitettiin ilma- ja sadevesinäytteiden radioaktiivisuuksien analysointi, kun ilmakehässä suurvaltojen toimesta tehtyjen ydinräjähteiden jäljiltä radioaktiivisen säteilyn määrä oli kohoamassa maassammekin selvästi yli luonnollisen tason. Ilmatieteen laitos piti osaltaan yllä säteilyn valvontaan liittyviä mittauksia ja tutkimusta. Toiminnan alkuaikoina pääosan radioaktiivisuuteen liittyvistä töistä teki FM Rolf Mattsson (1933–). 1960- ja 1970-luvuilla Nurmijärven observatorion operatiiviselle vastuulle perustettiin useita eri maiden rahoittamia havaintolaitteita. Tärkeitä toimijoita olivat Saksan Max-Planck-Instituutti ja Alaskan yliopisto. Edellinen ionosfääriluotaimen kautta ja jälkimmäinen magneettisten pulsaatioiden osalta. Yhteistyö Oulun yliopiston ja Sodankylän geofysiikan observatorion kanssa oli tiivistä. 1970-luvulta lähtien käynnistyi havainto- ja rekisteröintijärjestelmien automatisointi ja siirtyminen digitaalisiin laitteisiin. Observatorion alkuajoista lähtien toimineet analogiset magneettiset rekisteröinnit uusittiin moderneilla digitaalisilla laitteilla 1990-luvulla, jolloin valokuvausperiaatteella toimineet rekisteröinnit voitiin lopettaa. Magneettiset absoluutti-instrumentit korvattiin samoihin aikoihin uusilla ajanmukaisilla laitteilla. Samoja magnetometrejä hankittiin myös magnetometriverkon IMAGE käyttöön eri puolilla Suomea. Nurmijärven magneettiset rekisteröinnit liitettiin vuonna 1991 kansainväliseen INTERMAGNET-verkkoon, jolloin observatorion magneettiset datat ovat reaaliajassa käytettävissä maailmalla esimerkiksi avaruussään monitorointiin. Magnetismin alalla uutena toimintamuotona käynnistyi 1990-luvulla magneettinen testilaboratorio, missä voitiin kalibroida erilaisia magneettikenttää mittavia laitteita. Laboratorio erikoistui myös avaruuteen lähetettävien mittalaitteiden magneettisen puhtauden määrityksiin. Työtä tehtiin muun muassa yhdessä ukrainalaisen avaruustutkimuslaitoksen kanssa. Magneettinen testilaboratorio akkreditoitiin (MIKES) vuonna 2007, mutta sen toiminta on keskeytynyt. Kaikkiaan Nurmijärven observatoriossa on ollut toiminnassa 15 erilaista geofysikaalista rekisteröintijärjestelmää. Niistä osa on ollut ulkomaisten yhteistyötahojen havaintolaitteistoja, mutta merkittävä yhteistyökumppani havaintojen alalla on ollut Sodankylän geofysiikan observatorio. Nurmijärven observatorion rekisteröintien automatisointi ja havaintojen liittäminen tietoliikenneverkkoihin vähensi tarvetta ylläpitää observatoriolla vakinaista henkilökuntaa, koska tarvittavat huoltotoimet ja mittaukset voidaan pääasiassa tehdä Helsingistä käsin. Samalla tarpeettomiksi käyneet asuinrakennukset ja käytöstä poistuneet vanhentuneet mittauskopit voitiin purkaa.