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1

Liu, Fangyuan, Shiqi Lin, Caiyun Zhang, Jiahui Ma, Zhuo Han, Fujuan Jia, Weidong Xie und Xia Li. „The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro“. Medicina 55, Nr. 8 (12.08.2019): 470. http://dx.doi.org/10.3390/medicina55080470.

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Background and Objectives: Microtubules are an attractive target for cancer chemotherapy. Previously, we reported that Ivalin exhibited excellent anti-migration and anti-invasion activities in human breast cancer cells. Here, we examined the microtubule inhibition effect of Ivalin in human hepatocellular carcinoma SMMC-7721 cells. Materials and Methods: We used the 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium bromide (MTT) assay to evaluate the cell proliferation effect of Ivalin and flow cytometry analysis to detect the apoptotic and cell cycle arrest effects of Ivalin. Immunofluorescence staining was used to measure the effect of Ivalin on the cytoskeleton network, and Western blotting was used to detect the expression levels of Bax, Bcl-2, Cdc2, phosphor-Cdc2, Cdc25A, Cyclin B1, and tubulin. Results: Ivalin induced cell cycle G2/M arrest and subsequent triggered apoptosis in human hepatocellular carcinoma SMMC-7721 cells. Furthermore, microtubules were shown to be involved in Ivalin-meditated apoptosis. In this connection, Ivalin treatment suppressed cellular microtubule network formation by regulating microtubule depolymerization. Moreover, Western blotting revealed Cdc25A and Cyclin B1 were upregulated in Ivalin-meditated cell cycle arrest. Subsequently, the induction of Bax (a proapoptotic protein) and reduction of Bcl-2 (an anti-apoptotic protein) expression were observed in Ivalin-treated SMMC-7721 cells. Conclusion: Ivalin induced microtubule depolymerization, then blocked cells in mitotic phase, and eventually resulted in apoptosis in SMMC-7721 cells. Collectively, these data indicate that Ivalin, acting as a novel inhibitor of microtubules, could be considered as a promising lead in anticancer drug development.
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2

Han, Zhuo, Fang-yuan Liu, Shi-qi Lin, Cai-yun Zhang, Jia-hui Ma, Chao Guo, Fu-juan Jia, Qian Zhang, Wei-dong Xie und Xia Li. „Ivalin Induces Mitochondria-Mediated Apoptosis Associated with the NF-κB Activation in Human Hepatocellular Carcinoma SMMC-7721 Cells“. Molecules 24, Nr. 20 (22.10.2019): 3809. http://dx.doi.org/10.3390/molecules24203809.

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Ivalin, a natural compound isolated from Carpesium divaricatum, showed excellent microtubule depolymerization activities among human hepatocellular carcinoma in our previous work. Here, we investigated its functions on mitochondria-mediated apoptosis in hepatocellular carcinoma SMMC-7721 cells. DAPI (4′,6-diamidino-2-phenylindole) staining, annexin V-fluorexcein isothiocyanate (FITC) apoptosis detection, and western blotting were applied to explore the apoptotic effect of Ivalin. Next, the induction effect of Ivalin on the mitochondrial pathway was also confirmed via a series of phenomena including the damage of mitochondria membrane potential, mitochondria cytochrome c escape, cleaved caspase-3 induction, and the reactive oxygen species generation. In this connection, we understood that Ivalin induced apoptosis through the mitochondrial pathway and the overload of reactive oxygen species. Furthermore, we found that the activation of nuclear factor-κB (NF-κB) and subsequent p53 induction were associated with the apoptotic effect of Ivalin. These data confirmed that Ivalin might be a promising pro-apoptotic compound that can be utilized as a potential drug for clinical treatment.
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3

Bernal-Morales, Ernesto, Alfonso Romo De Vivar, Bertha Sanchez, Martha Aguilar und Blas Lotina-Hennsen. „Inhibition of oxygen evolution by ivalin“. Canadian Journal of Botany 72, Nr. 2 (01.02.1994): 177–81. http://dx.doi.org/10.1139/b94-024.

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The inhibition of ATP synthesis, proton uptake, and electron transport (basal, phosphorylating, and uncoupled) from water to methylviologen by ivalin (a naturally occurring sesquiterpene lactone in Zaluzania triloba and Iva microcephala) indicates that it acts as electron transport inhibitor. Since photosystem I and electron transport from DPC to QA were not affected, while the electron flow of uncoupled photosystem II from H2O to DAD and from water to silicomolybdate was inhibited, we concluded that the site of inhibition of ivalin is located at the oxygen evolution level. Key words: oxygen evolution, ivalin, photosynthesis, sesquiterpene lactone.
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4

Botha, Christo J., Y. Zethu Mathe, Gezina C. H. Ferreira und E. Annette Venter. „Cytotoxicity of the Sesquiterpene Lactones, Ivalin and Parthenolide in Murine Muscle Cell Lines and Their Effect on Desmin, a Cytoskeletal Intermediate Filament“. Toxins 12, Nr. 7 (18.07.2020): 459. http://dx.doi.org/10.3390/toxins12070459.

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Vermeersiekte or “vomiting disease” is an economically important disease of ruminants following ingestion of Geigeria (G.) species in South Africa. Sheep are more susceptible, and poisoning is characterized by stiffness, regurgitation, bloat, paresis, and paralysis. Various sesquiterpene lactones have been implicated as the cause of poisoning. The in vitro cytotoxicity of two sesquiterpene lactones, namely, ivalin (purified from Geigeria aspera) and parthenolide (a commercially available sesquiterpene lactone), were compared using mouse skeletal myoblast (C2C12) and rat embryonic cardiac myocyte (H9c2) cell lines, representing the oesophageal, skeletal and cardiac muscles, which are affected in sheep. For 24, 48, and 72 h, both cell lines were exposed. A colorimetric viability assay, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), was used to assess cytotoxicity. A concentration-dependent cytotoxic response was observed in both cell lines, however, the C2C12 cells were more sensitive, with the half-maximal effective concentrations (EC50s) ranging between 2.7 and 3.3 µM. In addition, the effect that ivalin and parthenolide has on desmin, an important cytoskeletal intermediate filament in myocytes, was evaluated using the C2C12 myoblasts. Disorganization and aggregation of desmin were caused by both sesquiterpene lactones, which could clarify some of the ultrastructural lesions described in vermeersiekte.
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5

Ivanova, Victoria, Antoaneta Trendafilova, Milka Todorova, Kalina Danova und Dimitar Dimitrov. „Phytochemical Profile of Inula britannica from Bulgaria“. Natural Product Communications 12, Nr. 2 (Februar 2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200201.

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The flower heads of Inula britannica L. of Bulgarian origin afforded sesquiterpene lactones (gaillardin, britannin, 11,13-dihydroinuchinenolide B, ivalin, pulchellin C), triterpenoids (3- O-palmitates of 16β-hydroxylupeol, 16β-hydroxy-β-amyrin, and faradiol) and flavonoids (quercetin, luteolin, luteolin-7- O-glucoside). All compounds are known and they were identified by spectral methods. The observed differences in the chemical content of the chloroform and methanol extracts were also reflected in their free radical scavenging activity, evaluated by DPPH and ABTS assays. Intraspecific variability of I. britannica is discussed.
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Shah, Muhammad Dawood, Kazuki Tani, Yoong Soon Yong, Fui Fui Ching, Sitti Raehanah Muhamad Shaleh, Charles S. Vairappan und Balu Alagar Venmathi Maran. „Antiparasitic Potential of Chromatographic Fractions of Nephrolepis biserrata and Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometry Analysis“. Molecules 26, Nr. 2 (19.01.2021): 499. http://dx.doi.org/10.3390/molecules26020499.

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Marine aquaculture development is recently impeded by parasitic leech Zeylanicobdellaarugamensis (Hirudinea, Piscicolidae) in Sabah, Malaysia. The parasitic leech infests a variety of cultured fishes in aquaculture facilities. In this study, we evaluated the antiparasitic activity of the chromatographic fractions of the medicinal plant Nephrolepis biserrata methanol extract against Z.arugamensis and highlighted the potential metabolites responsible for the antiparasitic properties through liquid chromatography (LC)–quadrupole time-of-flight (QTOF)–mass spectrometry (MS) analysis. Out of seven fractions obtained through flash column chromatography techniques, three fractions demonstrated antiparasitic properties. Significant parasitic mortality was indicated by fraction 3 at a concentration of 2.50 mg/mL, all the leeches were killed in a time limit of 1.92 ± 0.59 min. followed by fraction 4 (14 mg/mL) in 34.57 ± 3.39 and fraction 5 (15.3 mg/mL) in 36.82 ± 4.53 min. LC-QTOF-MS analysis indicated the presence of secondary metabolites including phytosphingosine (6), pyrethrosin (1), haplophytine (9), ivalin (2), warburganal (3), isodomedin (4) and pheophorbide a (16), representing sphingoid, alkaloid, terpenoid, phenolic and flavonoid groups. Thus, our study indicated that the chromatographic fractions of N. biserrata demonstrated significant antiparasitic activity against the marine parasitic leeches due to the presence of potent antiparasitic bioactive compounds.
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Ma, Jia-Hui, Jie Qi, Fang-Yuan Liu, Shi-Qi Lin, Cai-Yun Zhang, Wei-Dong Xie, Hang-Yu Zhang und Xia Li. „Ivalin Inhibits Proliferation, Migration and Invasion by Suppressing Epithelial Mesenchymal Transition in Breast Cancer Cells“. Nutrition and Cancer 70, Nr. 8 (17.11.2018): 1330–38. http://dx.doi.org/10.1080/01635581.2018.1539185.

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8

van Aswegen, Casper H., und James L. Wittliff. „Steroid hormone‐receptor activity in the presence of a mycotoxic phomopsin toxin and the sesquiterpene ivalin toxin“. Journal of Toxicology and Environmental Health 16, Nr. 1 (Januar 1985): 1–12. http://dx.doi.org/10.1080/15287398509530714.

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9

Karpiński, Tomasz M., Marcin Ożarowski, Agnieszka Seremak-Mrozikiewicz, Hubert Wolski und Artur Adamczak. „Plant Preparations and Compounds with Activities against Biofilms Formed by Candida spp.“ Journal of Fungi 7, Nr. 5 (05.05.2021): 360. http://dx.doi.org/10.3390/jof7050360.

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Fungi from the genus Candida are very important human and animal pathogens. Many strains can produce biofilms, which inhibit the activity of antifungal drugs and increase the tolerance or resistance to them as well. Clinically, this process leads to persistent infections and increased mortality. Today, many Candida species are resistant to drugs, including C. auris, which is a multiresistant pathogen. Natural compounds may potentially be used to combat multiresistant and biofilm-forming strains. The aim of this review was to present plant-derived preparations and compounds that inhibit Candida biofilm formation by at least 50%. A total of 29 essential oils and 16 plant extracts demonstrate activity against Candida biofilms, with the following families predominating: Lamiaceae, Myrtaceae, Asteraceae, Fabaceae, and Apiacae. Lavandula dentata (0.045–0.07 mg/L), Satureja macrosiphon (0.06–8 mg/L), and Ziziphora tenuior (2.5 mg/L) have the best antifungal activity. High efficacy has also been observed with Artemisia judaica, Lawsonia inermis, and Thymus vulgaris. Moreover, 69 plant compounds demonstrate activity against Candida biofilms. Activity in concentrations below 16 mg/L was observed with phenolic compounds (thymol, pterostilbene, and eugenol), sesquiterpene derivatives (warburganal, polygodial, and ivalin), chalconoid (lichochalcone A), steroidal saponin (dioscin), flavonoid (baicalein), alkaloids (waltheriones), macrocyclic bisbibenzyl (riccardin D), and cannabinoid (cannabidiol). The above compounds act on biofilm formation and/or mature biofilms. In summary, plant preparations and compounds exhibit anti-biofilm activity against Candida. Given this, they may be a promising alternative to antifungal drugs.
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10

van Aswegen, Casper H., Walter M. Lewko und James L. Wittliff. „Influence of phomopsin and ivalin on steroid‐hormone binding and growth of mcf‐7 human breast cancer cells“. Journal of Toxicology and Environmental Health 16, Nr. 1 (Januar 1985): 13–23. http://dx.doi.org/10.1080/15287398509530715.

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11

Tomioka, Kiyoshi, Fumio Masumi, Toyoharu Yamashita und Kenji Koga. „Stereoselective reactions. 15.1 total synthesis of (+)-ivalin by utilizing asymmetric double alkylation reaction of α,β-unsaturated aldimine“. Tetrahedron 45, Nr. 3 (Januar 1989): 643–50. http://dx.doi.org/10.1016/0040-4020(89)80093-6.

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12

DUCKETT, CATHERINE N., K. D. PRATHAPAN und ALEXANDER S. KONSTANTINOV. „Notes on identity, new synonymy and larva of Ivalia Jacoby (Coleoptera: Chrysomelidae) with description of a new species“. Zootaxa 1363, Nr. 1 (23.11.2006): 49. http://dx.doi.org/10.11646/zootaxa.1363.1.4.

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Genus Ivalia Jacoby is characterized morphologically, and Amphimeloides Jacoby syn. nov. and Taizonia Chen syn. nov. are junior synonyms with it. Several Ivalia species are figured, including Ivalia bella (Chen) comb. nov., I. dorsalis (Jacoby) comb. nov., and I. viridipennis Jacoby. A new species of Ivalia from the Nilgiri Hills in south India, I. korakundah sp. nov., is described and illustrated, including the larvae. Larvae were associated with adults by sequencing a fragment of the mitochondrial gene cytochrome oxidase I. Larval morphology is discussed and compared with that of other flea beetles.
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13

Takizawa, Haruo, und Alexander S. Konstantinov. „The genus Ivalia Jacoby 1887 (Coleoptera: Chrysomelidae: Galerucinae: Alticini) of the mount Kinabalu, Sabah, Malaysia“. Journal of Insect Biodiversity 6, Nr. 1 (01.01.2018): 1. http://dx.doi.org/10.12976/jib/2018.6.1.

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The following new species of Ivalia Jacoby 1887 are described from the mount Kinabalu (Sabah, Malaysia): Ivalia besar sp. nov., I. biasa sp. nov., I. fulvomaculata sp. nov., I. haruka sp. nov., I. marginata sp. nov., I. minutissima sp. nov., I. nigrofasciata sp. nov., I. pseudostriolata sp. nov., I. rubrorbiculata sp. nov., I. striolata sp. nov..
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Diaz, E., J. L. Nava, H. Barrios, B. Quiroz, A. Guzman, L. León G und A. Fuentes B. „2D 1H and 13C NMR evidence for stereoselective formation of a new bond C–N, C–S or C–C in the reaction of ivalin acetate with substituted pyrimidines“. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 54, Nr. 4 (April 1998): 567–74. http://dx.doi.org/10.1016/s1386-1425(97)00245-x.

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15

Tisnado, J., S. R. Cho, M. C. Beachley und D. A. Margolius. „Transcatheter Embolization of Angiodysplasia of the Rectum“. Acta Radiologica. Diagnosis 26, Nr. 6 (November 1985): 677–80. http://dx.doi.org/10.1177/028418518502600606.

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A 51-year-old man with repeated and massive rectal bleeding was found to have a large angiodysplasia of the rectum. A superselective embolization of the distal part of the superior rectal artery with Ivalon controlled the rectal bleeding for 4 months. Lower gastrointestinal bleeding recurred and a recurrent lesion was re-embolized with Ivalon with excellent control of bleeding in a follow-up of 8 months. Embolization is an alternative to surgery for the treatment of rectal angiodysplasia and hopefully may result in a long-term cure.
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Damaška, Albert F., Dale Joy Mohagan und Martin Fikácek. „Moss-inhabiting flea beetles in the Philippines (Coleoptera, Chrysomelidae, Alticinae)“. ZooKeys 960 (17.08.2020): 125–42. http://dx.doi.org/10.3897/zookeys.960.54011.

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The Philippine islands are one of the key biodiversity hotspots in the Indo-Pacific area. Knowledge of moss-inhabiting flea beetles (Coleoptera: Chrysomelidae: Alticinae), a diverse and ecologically and morphologically enigmatic group in the Philippines is described. Six species from the Philippines are recorded, belonging to three genera: Benedictus luzonicus Sprecher-Uebersax et al., 2009 (recorded from the Philippines previously), Ivalia antennatasp. nov., I. caligulatasp. nov. and I. postfasciata (Chen, 1934), comb. nov. (transferred from Chabria Jacoby, 1887), Cangshanaltica mindanaoensissp. nov., and C. luzonicasp. nov. Cox1 barcode sequences of Ivalia antennata and Cangshanaltica mindanaoensis are presented. Biogeography and diversity of moss-inhabiting flea beetles in the Philippines are discussed.
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17

Zhitenev, Aleksandr. „Poetology of Vyktor Ivaniv“. Litera, Nr. 8 (August 2020): 116–26. http://dx.doi.org/10.25136/2409-8698.2020.8.33616.

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The subject of this research is the corpus of auto-reflexive texts of the contemporary poet Vyktor Ivaniv – his research, essayistic, literary-critical writings. The goal consists in reconstruction of V. Ivaniv’s poetology, which implies the system of representations on ultimate characteristics of poetry, poeticity, and poetic. It is established that poetological system of V. Ivaniv can be described as an example of radicalization of “magic” intentions of historical avant-garde. The novelty of V. Ivaniv consists in reassessment of the ideas of transformation of the world using such term as “utopic”. Having determined the genetic affinity of the constructs of Russian avant-gardists with the ideas of Nicholas of Cusa, Rene Descartes and Gottfried Wilhelm Leibniz, Ivaniv highlights their rootedness in the traditions of European rationalism. The novelty of the research lies in the comprehensive analysis, which allows restoring a universal system of representations on poetry based on the comparison of texts belonging to different types of discourse. Formulation of aesthetic principles in Ivaniv’s works is inseparable from philological reflection over the nature of symbol and its typology. Analyzing the principles of the construction of image at different stages of the establishment of avant-garde mentality, V. Ivaniv creates the concept of iconic symbol as a substitute of the event and a semantic operator, which replaces false meanings with true ones. According to Ivaniv, transgressive introduction to the truth of being – ecstatic and dangerous – comprises the essence of the poetic.
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van der Houwen, Eduard B., Tjouwke A. van Kalkeren, Johannes G. M. Burgerhof, Bernard F. A. M. van der Laan und Gijsbertus J. Verkerke. „In Vitro Evaluation of the iValve: A Novel Hands-Free Speech Valve“. Annals of Otology, Rhinology & Laryngology 120, Nr. 12 (Dezember 2011): 814–19. http://dx.doi.org/10.1177/000348941112001207.

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Objectives: We performed in vitro evaluation of a novel, disposable, automatic hands-free tracheostoma speech valve for laryngectomy patients based upon the principle of inhalation. The commercially available automatic speech valves close upon strong exhalation and open again when the pressure drops. This method makes long sentences or pauses difficult. The novel iValve is designed to allow almost natural speech, with mid-sentence pausing and whispering. Methods: The inhalation closing flows and exhalation opening pressures of 6 iValve prototype versions at different settings were compared with physiological values. The airflow resistance at inhalation was compared to physiological values and to commercial valve values. Results: The iValve prototypes showed flow and pressure ranges in concordance with the physiological values in the literature. The airflow resistance in the breathing mode was within the physiological airflow resistance range, yet above the values from the two commercial valves. The resistance in the speaking mode was above the physiological airflow resistance range. Conclusions: In vitro tests show that the iValve versions can be selected and adjusted to operate within the physiological range. The airflow resistance in the breathing mode is good. In speaking mode, inhalation should, and can, be decreased. The iValve should offer the patient a more intuitively useable alternative with more dynamic speech. Its low cost allows disposability and wider use.
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Rados, Zvjezdana. „Profesoru Nikoli Ivanišinu (1923.-2013.) u spomen“. Croatica et Slavica Iadertina 2, Nr. 9 (21.02.2014): 548. http://dx.doi.org/10.15291/csi.818.

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20

Damaška, Albert F., und Paul Aston. „Leaf litter and moss-inhabiting flea beetles of Hong Kong (Coleoptera: Chrysomelidae: Alticini)“. Acta Entomologica Musei Nationalis Pragae 59, Nr. 1 (01.10.2019): 151–61. http://dx.doi.org/10.2478/aemnp-2019-0013.

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Abstract The flea beetles (Coleoptera: Chrysomelidae: Galerucinae: Alticini) inhabiting leaf litter and moss in Hong Kong are reviewed and summarized for the first time. Five species are listed from Hong Kong, four of which are newly described: Benedictus sagittalis sp. nov., Cangshanaltica sprynari sp. nov., Clavicornaltica doeberli sp. nov. and C. longipenis sp. nov. Ivalia excavata (Wang, 1993) is recorded from Hong Kong for the first time. All species are photographed and their species identity is discussed.
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Gorla, José Irineu, und Claudio Diehl Nogueira. „Esporte adaptado e formação de recursos humanos: experiências construídas na área“. Conexões 14, Nr. 2 (02.08.2016): 158. http://dx.doi.org/10.20396/conex.v14i2.8646060.

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Este ensaio apresenta experiências práticas sobre a formação de recursos humanos e o esporte para Pessoas com deficiências. O professor Ivaldo Brandão tem experiência de 34 anos com o envolvimento do esporte adaptado, especificamente na área da Paralisia Cerebral, sendo uma referencia nessa área com diversos ensaios publicados e com aplicabilidade na formação de recursos humanos na referida área. As experiências apontadas pelo professor Ivaldo Brandão, certamente contribuíram para os avanços da área continuaram sendo referência para alavancar novos rumos e tendências na área de pesquisa.
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Bhansali, Sanjay, Harvey Wilner und John R. Jacobs. „Arterial embolization for control of bleeding in advanced head and neck carcinoma“. Journal of Laryngology & Otology 100, Nr. 11 (November 1986): 1289–93. http://dx.doi.org/10.1017/s0022215100100994.

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AbstractThere are a number of patients with unresectable recurrent carcinoma of the head and neck who continue to lead a relatively functional life despite advanced local disease. For these patients bleeding from tumor represents a devastating complication that can abruptly terminate the course of an otherwise chronic disease, albeit a uniformly fatal one. The technique we describe renders a relatively safe and effective treatment that seems to control this problem.We report on our experience with three patients whose tumor bleeding was controlled by permanent intra-arterial embolization with Ivalon, a polyvinyl alcohol-based foam. The technique, indications, and complications are discussed.
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Silva-Castro, Milene Maria, und Luciano Paganuccii Queiroz. „Five new species of Mansoa DC. (Bignoniaceae) from South America“. Phytotaxa 258, Nr. 1 (26.04.2016): 49. http://dx.doi.org/10.11646/phytotaxa.258.1.3.

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Mansoa (Bignoniaceae: Bignonieae) is a Neotropical genus of lianas distributed through Wet and Seasonally Dry Forests. The genus is characterized by striated bark, extrafloral nectaries on the abaxial surface of leaflets, trifid tendrils, and garlic odor. During a taxonomic revision of the genus, five new species were discovered in South America, increasing to 16 the number of recognized species in Mansoa. Four of these taxa, Mansoa ivanii, Mansoa longicalyx, Mansoa minensis and Mansoa paganuccii, are restricted to eastern portions of Brazil, while Mansoa gentryi is found in Peruvian rainforests. Mansoa ivanii, M. longicalyx, and M. minensis share pubescent branches and leaflets with Mansoa hirsuta, but differ by the corolla length and calyx morphology. Mansoa paganuccii shares ovate to elliptic leaflets and a lack of garlic odor with Mansoa difficilis and Mansoa angustidens, but differs by the serrate leaflets and mucronate calyx. Mansoa gentryi shares chartaceous and elliptic leaflets with Mansoa alliacea, but differs by the pinnate venation and ribbed capsules.
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Quinderé, Natália, Ivair Reinaldim, Bernardo Mosqueira, Brígida Baltar, Alex Hamburger, Rosângela Rennó, Ricardo Basbaum et al. „Visorama, a entrevista“. Revista Concinnitas 20, Nr. 36 (28.01.2020): 60–98. http://dx.doi.org/10.12957/concinnitas.2019.47955.

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Gerbaudo, Analía. „Sobre: El tiempo de la convalecencia. Fragmentos de un diario en Facebook, de Alberto Giordano“. El Taco en la Brea, Nr. 7 (06.06.2018): 201–11. http://dx.doi.org/10.14409/tb.v0i7.7366.

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Thomas, R., J. Deasy und D. Royston. „Retrorectal pseudotumour induced by Ivalon“. Histopathology 39, Nr. 6 (Dezember 2001): 640–41. http://dx.doi.org/10.1046/j.1365-2559.2001.1311c.x.

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Evdokimov, Yu M., I. N. Gerasimova, T. G. Grusheva und A. G. Stepanov. „D.I. Mendeleev and Periodic system. Continued“. FORESTRY BULLETIN 25, Nr. 1 (Februar 2021): 109–14. http://dx.doi.org/10.18698/2542-1468-2021-1-109-114.

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There has been presented a discussion of the article by G.L. Oliferenko, A.N. Zarubina, A.V. Ustyugova, A.N. Ivankin «To the 150th anniversary of the Periodic Table of Chemical Elements by D.I. Mendeleev», published in Forestry Bulletin, 2019, vol. 23, no. 6, pp. 117-123. DOI: 10.18698 / 2542-1468-2019-6-117-123
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Berniker, Max, David W. Franklin, J. Randall Flanagan, Daniel M. Wolpert und Konrad Kording. „Motor learning of novel dynamics is not represented in a single global coordinate system: evaluation of mixed coordinate representations and local learning“. Journal of Neurophysiology 111, Nr. 6 (15.03.2014): 1165–82. http://dx.doi.org/10.1152/jn.00493.2013.

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Successful motor performance requires the ability to adapt motor commands to task dynamics. A central question in movement neuroscience is how these dynamics are represented. Although it is widely assumed that dynamics (e.g., force fields) are represented in intrinsic, joint-based coordinates (Shadmehr R, Mussa-Ivaldi FA. J Neurosci 14: 3208–3224, 1994), recent evidence has questioned this proposal. Here we reexamine the representation of dynamics in two experiments. By testing generalization following changes in shoulder, elbow, or wrist configurations, the first experiment tested for extrinsic, intrinsic, or object-centered representations. No single coordinate frame accounted for the pattern of generalization. Rather, generalization patterns were better accounted for by a mixture of representations or by models that assumed local learning and graded, decaying generalization. A second experiment, in which we replicated the design of an influential study that had suggested encoding in intrinsic coordinates (Shadmehr and Mussa-Ivaldi 1994), yielded similar results. That is, we could not find evidence that dynamics are represented in a single coordinate system. Taken together, our experiments suggest that internal models do not employ a single coordinate system when generalizing and may well be represented as a mixture of coordinate systems, as a single system with local learning, or both.
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Pust Škrgulja, Vida. „Antika kot likovna inspiracija“. Keria: Studia Latina et Graeca 1, Nr. 1-2 (31.12.1999): 79. http://dx.doi.org/10.4312/keria.1.1-2.79-86.

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Tema tega razmišljanja, ki se je razvijala in oblikovala postopno, predvsem v zadnjih nekaj letih pripravljanja programov za pouk latinščine in likovne umetnosti na gimnaziji v hrvaškem Ivanić Gradu, je zrasla iz želje, da bi se mlademu človeku na zgoščen, a vendar dovolj pregleden in jasen način približalo bogastvo sveta antičnega človeka, kakor se kaže skozi stoletja razvoja evropske in delno tudi zunajevropske likovne umetnosti. Zato naj ne zamerijo tisti, ki so prepričani, da tema zahteva zgolj znanstveno obravnavo.
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Jamali, Mohamad, und Hamid Najafpour Sani. „Representation and Construction of Self in Writing Discourses“. International Letters of Social and Humanistic Sciences 46 (Januar 2015): 77–98. http://dx.doi.org/10.18052/www.scipress.com/ilshs.46.77.

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The "discoursal self', according to Ivanic, is "the impression... they [the students] consciously or unconsciously convey... in a particular written text... . It is constructed through the discourse characteristics of a text, which relate to values, beliefs, and power relations in the social context in which they were written" (25). The "autobiographical self," Ivanic explains, "is the identity which people bring with them to any act of writing" (24). The goal for this paper is an overview investigating whether or not students are aware of a discoursal self-being constructed for them as a result of being students in another academic environment. The author begins by exploring the theoretical concepts of the socially constructed "self', language and how language is used by society to influence the individual. Further, he narrows the focus and reviews the field of literature by Rhetoric and Composition scholars who have explored the issues and impacts of teaching academic discourse to students. If we attempt to understand what the students think and how they perceive the writing, we may be able to better tailor our assignments, methods and approaches to better fit the needs of the students. The findings and results of my thesis may be of benefit to educators and other professionals across the world. The text will also provide a safe, anonymous, respectable outlet for students to voice their opinions and thoughts.
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Yasuda, K. „Ivalon sponge occlusion method for aortic dissection.“ Japanese Journal of Cardiovascular Surgery 17, Nr. 2 (1987): 133–35. http://dx.doi.org/10.4326/jjcvs.17.133.

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Ioannidou, E., A. P. Leppänen, D. Melas und A. Ioannidou. „Time lag between the tropopause height and the levels of 7Be concentrations in surface air“. HNPS Proceedings 24 (01.04.2019): 102. http://dx.doi.org/10.12681/hnps.1851.

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The concentration of 7Be at near surface air has been determined over 2009, which was a year of a deep solar minimum, at three different locations in Finland: Ivalo (68°64’N, 27°57’E), Rovaniemi (66°51’N, 25°68’E) and Kotka (60°48’N, 26°92’E). In geomagnetic latitudes over λ = 60° N, the elevation of tropopause during the warm summer months and the vertical exchange of air masses within the troposphere cause greater mixture of the air masses resulting in higher concentration levels for 7Be in surface air. However, different climatic phenomena, such as air masses from the East, make the correlation between the monthly activity concentrations of 7Be and the tropopause height fairly weak. For Ivalo and Rovaniemi it was found that changes in the daily surface concentrations of 7Be lag the changes in the elevation of the tropopause by four days. In Kotka, the correlation is weakest.
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Vaghi, M. A., M. Bracchi, C. Cimino und L. Strada. „Considerazioni generali sulla diagnosi ed il trattamento delle malformazioni artero-venose durali del rachide spinale“. Rivista di Neuroradiologia 1, Nr. 1 (April 1988): 81–90. http://dx.doi.org/10.1177/197140098800100109.

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Per la diagnosi ed il trattamento delle MAV durali e spinali è necessaria l'angiografia spinale selettiva. Poiché è opportuno un bilancio angiografico il più completo possibile e poiché talora l'esplorazione deve essere estesa al di fuori del rachide, preferiamo avere una ragionevole certezza della presenza di una MAV prima di iniziare l'angiografia. Questa certezza la cerchiamo con la mielografia. In determinate condizioni anche la RM può fare diagnosi di MAV ed è augurabile che in futuro questo esame possa sostituire la mielografia o quanto meno rappresentare un mezzo valido e non invasivo per il controllo dopo trattamento. Da quando è stata resa nota la natura di queste MAV durali, il trattamento, sia di embolizzazione che chirurgico, dovrebbe limitarsi ad interrompere il flusso tra MAV durale e plesso perimidollare. Come materiale d'embolizzazione abbiamo usato inizialmente il Bucrilato, attualmente preferiamo le particelle di Ivalon, di più facile impiego rispetto alle colle. Sottoponiamo al chirurgo i casi di recidiva e i casi in cui la situazione dell'arteria spinale anteriore rappresenta un pericolo per l'embolizzazione.
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Nieminen, Mauri, Harri Norberg und Veikko Maijala. „Mortality and survival of semi-domesticated reindeer (Rangifer tarandus tarandus L.) calves in northern Finland“. Rangifer 31, Nr. 1 (01.04.2011): 71–84. http://dx.doi.org/10.7557/2.31.1.2029.

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During the period 1999 to 2004 the reindeer calf survival and mortality were studied in two reindeer-herding cooperatives and in five herding-groups in northern Finland, where in total 1725 calves were fitted with mortality indicating radio-transmitters fixed on expandable neck collars. The calves were weighed and marked at the age of 2-5 days in calving corrals and also during earmarking in June/July, when the age of calves was 2-8 weeks. The rate, timing and causes of mortality of calves were investigated. In 1999-2001 in Ivalo reindeer-herding cooperative 4.6% of radiocollared calves and in 2002-04 in Käsivarsi reindeer cooperative 5.2% was found dead. The average mortality of the calves radio-collared during calving time in May, and monitored to the end of October, was 6.7% in Ivalo and 9.0% in Käsivarsi. From July on, the average mortality rates varied between 1.8-5.7% among reindeer herding-groups. On average 54 and 42% of all radio-collared calves found dead in Ivalo and Käsivarsi cooperatives were attributed to predation, and golden eagle was the most significant cause of death in both cooperatives killing 0-3.5% of radio-collared calves in different study areas and years. Golden eagle predation accounted for 33-43% of all radio-collared calves found dead, 55-59% of the cases with identified cause of death and 80% of all identified predation. Most of the calves killed by golden eagle were found during July and August mainly in the open areas, as in highlands, bogs and clear-cut forest areas. The mean body weight of the calves radio-collared in May (weights adjusted on June 1st) and found dead during the summer was significantly (P<0.01) lighter than the mean weight of survivors both in Ivalo and Käsivarsi. Furthermore, the midsummer body weights of the calves (weights adjusted on July 1st) killed by all predators and by golden eagles were significantly (P<0.001) lower than the mean weight of surviving calves in both cooperatives. However, the weights did not differ between depredated calves and those calves that succumbed due to other causes than predation. The results of this study emphasize the relative importance of golden eagle as a mortality factor for reindeer calves in the northern part of the Finnish reindeer husbandry area.
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Rodríguez Allen, Ana Cecilia, und Anabelle Contreras Castro. „ENTREVISTA CON JORGE IVÁN ARANGO, MÉDICO DEL MODELO DE MEDICINA SINTERGÉTICA“. Revista PRAXIS, Nr. 79 (26.05.2019): 1–6. http://dx.doi.org/10.15359/praxis.79.6.

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El médico colombiano Jorge Iván Arango visitó Costa Rica, en el mes de noviembre de 2018, con motivo de la apertura del primer grupo de formación en Medicina Sintergética, e impartió el primer módulo. Esta es una propuesta nacida en Colombia y liderada por el Dr. Jorge Carvajal, que implica una concepción de vida y un replanteamiento de conceptos como: paciente, enfermedad, salud, terapeuta, curar, sanar, para ver al ser humano de forma integral. Para ello, reúne varios paradigmas y tradiciones, tanto de modelos de medicinas antiguas de otros países, como China e India, así como de aquellos ancestrales de nuestro continente, sin por ello querer competir o rechazar la medicina hegemónica. Antes bien, propone la integración, el estudio de los mínimos comunes de varios modelos y la enseñanza de la autogestión de la salud. El médico Jorge Iván Arango es un gran conocedor de las medicinas complementarias y un activo promotor de la salud auto- gestionada en las comunidades de bajos recursos.
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Laursen, Eric. „“A New Enigmatic Language”: The Spontaneity-Consciousness Paradigm and the Case of Gladkov's Cement“. Slavic Review 65, Nr. 1 (2006): 66–89. http://dx.doi.org/10.2307/4148523.

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Although Cement was a model for later socialist realism, Katerina Clark has argued that Gleb Chumalov does not achieve consciousness, a requirement for later heroes, but instead remains spontaneous. In this essay, Eric Laursen argues against Clark's widely accepted interpretation. By introducing the idea of instinct (class, worker, revolutionary), which Anna Krylova has shown to be central to Bolshevik thought in the early years of the twentieth century, Laursen argues that Gleb does gain consciousness. Gleb does not move from spontaneity to consciousness, however. Instead he learns to control and guide his own instincts and those of others. Two other characters also transform themselves. Gleb's wife Dasha illustrates a similar but distinct path forwomen. Sergei Ivagin, who must abandon conscious thought to first develop instinct, illustrates a different path for the intelligentsia. The attainment of consciousness is presented as a rebirth or maturation and involves the acquisition of “conscious language.” In the party purge at the end, those who speak unconsciously, therefore misleading and confusing the masses, are cast out of the party. The newly conscious Gleb and Dasha, who now speak properly, take their place as leaders.
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Gupta, Sanjay, Arvinder S. Soin, Subhash Gupta, Sadiq S. Sikora und Lalit K. Sharma. „SEPSIS AFTER IVALON SPONGE RECTOPEXK AN UNUSUAL CASE“. ANZ Journal of Surgery 61, Nr. 6 (Juni 1991): 469–71. http://dx.doi.org/10.1111/j.1445-2197.1991.tb00267.x.

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Vilke, Siniša, Livia Šantić und Matija Glad. „Redefining of the Rijeka Railway Junction“. PROMET - Traffic&Transportation 23, Nr. 6 (21.02.2012): 443–51. http://dx.doi.org/10.7307/ptt.v23i6.179.

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This paper presents and analyses the redefined Rijeka railway junction. The redefined concept of the Rijeka railroad hub in the context of port and railway interdependence dictates the need to find the accommodation of cargo transport to peripheral locations such as: Krasica, Kukuljanovo, Bakar, Ivani, Bršica and capacity for the island of Krk, while passenger transport would be implemented in the urban area. The most important projects related to Rijeka rail transport system are the construction of a new line of high efficiency between Zagreb and Rijeka, and a new railroad through the tunnel of Učka which will link the ports of Rijeka, Koper and Trieste. Together with the reconstruction of cargo stations Rijeka and Brajdica, an extension of the other tracks on the railroads Škrljevo-Rijeka and Rijeka-Opatija/Matulji should be performed as well as the construction of Krasica, Ivani, Tijani and Vrgljevo stations. The construction includes a multipurpose bridge to the Island of Krk and a railway line to the new container terminal as well as the new railway bypass to “elevation 200”. KEY WORDS: Rijeka railway junction, railway transport system, railway transport, Port of Rijeka
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Richard, J. C., M. Janier, F. Lavenne, V. Berthier, D. Lebars, G. Annat, F. Decailliot und C. Guerin. „Effect of position, nitric oxide, and almitrine on lung perfusion in a porcine model of acute lung injury“. Journal of Applied Physiology 93, Nr. 6 (01.12.2002): 2181–91. http://dx.doi.org/10.1152/japplphysiol.00313.2002.

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In a porcine model of oleic acid-induced lung injury, the effects of inhaled nitric oxide (iNO) and intravenous almitrine bismesylate (ivALM), which enhances the hypoxic pulmonary vasoconstriction on the distribution of regional pulmonary blood flow (PBF), were assessed. After injection of 0.12 ml/kg oleic acid, 20 anesthetized and mechanically ventilated piglets [weight of 25 ± 2.6 (SD) kg] were randomly divided into four groups: supine position, prone position, and 10 ppm iNO for 40 min followed by 4 μg · kg−1 · min−1ivALM for 40 min in supine position and in prone position. PBF was measured with positron emission tomography and H2 15O. The redistribution of PBF was studied on a pixel-by-pixel basis. Positron emission tomography scans were performed before and then 120, 160, and 200 min after injury. With prone position alone, although PBF remained prevalent in the dorsal regions it was significantly redistributed toward the ventral regions ( P < 0.001). A ventral redistribution of PBF was also obtained with iNO regardless of the position ( P = 0.043). Adjunction of ivALM had no further effect on PBF redistribution. PP and iNO have an additive effect on ventral redistribution of PBF.
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Masny, Diana. „Multiple Literacies Theory: how it functions, what it produces“. Perspectiva 28, Nr. 2 (14.07.2010): 337–52. http://dx.doi.org/10.5007/2175-795x.2010v28n2p337.

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At the moment, there are two literacy theories that seem to dominate the research on literacies. They are known as the New Literacy Studies (NLS) (BARTON; HAMILTON; IVANIČ; 2002; STREET, 2003) and Multiliteracies (COPE; KALANTZIS, 2009). This article is about a different theory, Multiple Literacies Theory (MLT) that demarcates itself from them ontologically and epistemologically. It will also highlight aspects of NLS and Multiliteracies in order to point out the differences with MLT. This article aims to put forward the major concepts that underlie this theory and present vignettes from a study examining how perceptions of writing systems in multilingual children contribute to reading, reading the world and self as texts.
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SCHRÄDER, RAINER, ROLAND HOFSTETTER, DIETER FABBENDER, FELIX BERGER, WULF-DIRK BUBMANN, JOSEF M. P. G. ERNST, WOLFGANG MATTHIES, NIKOLAUS REIFART, HORST SIEVERT und JOCELINO P. SOARES. „Transvenous Closure of Patent Ductus Arteriosus With Ivalon Plugs“. Investigative Radiology 34, Nr. 1 (Januar 1999): 65–70. http://dx.doi.org/10.1097/00004424-199901000-00010.

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42

HULMAN, G., und J. S. KIRKHAM. „Ivalon (polyvinyl alcohol) sponge presenting as an extrarectal mass“. Histopathology 16, Nr. 5 (03.04.2007): 502–4. http://dx.doi.org/10.1111/j.1365-2559.1990.tb01553.x.

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Miller, Donald L. „Failure of ivalon to provide permanent hepatic arterial occlusion“. Cardiovascular and Interventional Radiology 10, Nr. 2 (März 1987): 111–13. http://dx.doi.org/10.1007/bf02577980.

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Jovanović Simić, Jelena, und Dragomir Bondžić. „Stevan Ivanić (1884–1948) – prilog za biografiju“. Tokovi istorije 29, Nr. 2 (30.08.2021): 11–37. http://dx.doi.org/10.31212/tokovi.2021.2.jov.11-37.

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Stevan Ivanić was a Serbian physician and head of the Health Services in the Kingdom of Yugoslavia. A Socialist in his youth, in 1934 he joined the Zbor movement and promoted right-wing ideological views. He was commissar of social affairs and public health in 1941, and after the war he went into exile, where he died in 1948. The Communist authorities proclaimed him a criminal and traitor. So far, Ivanić’s biography has been available only in short encyclopedia entries. This paper is an attempt to supplement it with data from available archival material, periodicals and published literature and to present a fuller view of his professional and ideological-political activities and positions.
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Khashaba, Ahmed, Ayman Mortada und Azza Omran. „Intracoronary versus Intravenous Adenosine-Induced Maximal Coronary Hyperemia for Fractional Flow Reserve Measurements“. Clinical Medicine Insights: Cardiology 8 (Januar 2014): CMC.S11535. http://dx.doi.org/10.4137/cmc.s11535.

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Background Maximal hyperemia is the critical prerequisite for fractional flow reserve (FFR) assessment. Despite intravenous (IV) adenosine currently being the recommended approach, intracoronary (IC) administration of adenosine constitutes a valuable alternative in everyday practice. However, it is surprisingly unclear which IC strategy allows the achievement of FFR values that are comparable to IV adenosine. Objectives This study sought to compare increasing doses of IC adenosine versus IV adenosine for FFR. Methods 30 intermediate coronary stenoses undergoing FFR measurement were prospectively and consecutively enrolled. Hyperemia was sequentially induced by bolus of IC adenosine (ADN; 150 μg) followed by IV adenosine (IVADN) infusion over 3 minutes at dose of (140 μg/kg/min). FFR values, symptoms, and development of atrioventricular block were recorded. Results 150 μg doses of IC adenosine were well tolerated and associated with fewer symptoms than IV adenosine. Intracoronary adenosine doses induced a significant decrease of FFR compared with baseline levels ( P < 0.01). Among the 6 patients with FFR values less than 0.80 identified by IVADN, 4 were correctly identified also by 150 μg bolus IC adenosine. Larger randomized studies with cross-over design are necessary to verify the results. Conclusions This small pilot study suggests that IC adenosine might be an alternative to IV adenosine. Larger randomized studies with a cross-over design are necessary.
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Signor, Rita. „Sucesso em concursos públicos: um estudo sobre memórias e práticas de leitura em sujeitos que ingressaram na carreira pública federal“. Signo 38 (18.03.2013): 164. http://dx.doi.org/10.17058/signo.v38i0.4184.

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O objetivo deste estudo é traçar o perfil leitor de vinte sujeitos que ingressaram na carreira pública federal por meio de aprovação em concursos muito concorridos. Os dados foram gerados por meio de questionário com perguntas discursivas dirigidas para a investigação das memórias (GUEDES-PINTO, 1995) e práticas de leitura desses sujeitos. As bases que orientaram a análise foram Galvão (2004), Lahire (2008), Barton, Hamilton e Ivanic (2000), Kleiman (1995) e Street (1993;1995). Os resultados sugerem configurações de perfis “esperadas” em relação às trajetórias de leitura. Contudo, o percurso leitor de um dos sujeitos revelou uma configuração, que distante das influências familiares e escolares, colocou em evidência outras formas de mediação que foram determinantes para que o sujeito chegasse à elite escolarizada.
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Liebermann-Meffert, Dorothea, Martin Allgöwer und Thomas Rüedi. „Die Beziehungen Theodor Kochers zur «Société internationale de chirurgie»“. Gesnerus 49, Nr. 2 (27.11.1992): 201–11. http://dx.doi.org/10.1163/22977953-04902010.

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Mit dem Ziel, dem Fortschritt in der Chirurgie durch freundschaftlichen Erfah-rungsaustausch zu dienen, wurde im Jahre 1902 in Brüssel über die engen Grenzen nationalen Denkens hinweg die erste internationale Gesellschaft für Chirurgie gegründet. Als 1905 der erste Kongress stattfand, hatte die «Société Internationale de Chirurgie» (SIC) oder «International Society of Surgery» (ISS) bereits 638 Mitglieder; unter ihnen ivaren die bedeutendsten Chirurgen aus aller Veit. Theodor Kocher stand diesem Kongress als Präsident vor und war für seine Thematik verantwortlich. Seine Präsidialrede spiegelt die Ideale der Gesellschaft deutlich wieder. Die persönliche und fachliche Autorität Kochers, sein wissenschaftliches Konzept, das er so gerne seinen Kollegen weitervermittelte, und sein in ternationales Denken prägten die junge Gesellschaft, in deren Vorstand er bis zu seinem Tod 1917 blieb.
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Skjenneberg (ed.), Sven. „Research news; The new reindeer research station in Finland“. Rangifer 7, Nr. 2 (01.06.1987): 60. http://dx.doi.org/10.7557/2.7.2.721.

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<p>The new reindeer research station in Finland After a long planning time, it is now decided to build a reindeer research station in Finland. The station will be situated near Ivalo in Lapland, the northernmost county in Finland. Hopefully it will be completed within 1990. The floor space will be approximately 900 m2 and enclosures will cover more than 200 hectares. Completed, the staff will go up to 17, including 5 research officers who will cover different fields</p>
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Pemberton, J. W., und R. Offler. „Significance of clinopyroxene compositions from the Cudgegong Volcanics and Toolamanang Volcanics: Cudgegong-Mudgee district, NSW, Australia“. Mineralogical Magazine 49, Nr. 353 (September 1985): 591–99. http://dx.doi.org/10.1180/minmag.1985.049.353.14.

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SynopisClinopyroxene phenocrysts and groundmass crystals are relict phases in altered basalt and basaltic andesite lavas, and arenites of the Cudgegong Volcanics and Toolamanang Volcanics, Cudgegong-Mudgee district, New South Wales. Petrography, field relationships and clinopyroxene compositions indicate that basaltic blocks in the latter unit are reworked from the Cudgegong Volcanics. Clinopyroxene phenocrysts show a restricted compositional range and minor Feenrichment from core to rim, features considered indicative of a calc-alkaline parent magma. It is proposed that the Cudgegong Volcanics crystallized under hydrous conditions, at least in the later stages, with rising fO2 resulting in a Fe-Ti oxide crystallizing as a primary phase. The clinopyroxenes are considered to have crystallized at moderate (5–6 kbar) and falling pressures and at minimum temperatures in the range 900 to 1000°C. Coupled substitutions affecting the “other” components in the clinopyroxene structural formula indicate that the ivAl-viFe3+, ivAl-viAl and ivAl-viTi4+ couples are important. The Sofala Volcanics, south of the study area, and the Cudgegong Volcanics are similar in age, petrography and stratigraphic position, and contain relict clinopyroxenes which are chemically similar. This suggests that the units are laterally equivalent and adds further evidence to the proposal that an oceanic island arc system was active in central western New South Wales during the Late Ordovician.
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KOIKE, Tetsuo, Osamu SASAKI, Ryoji ISHII, Ryuichi TANAKA, Jusuke ITO, Kenjiro OZAKI, Hiroyuki ARAI, Shigeki KAMEYAMA und Kenichi TANIMURA. „Transcatheter Embolization with Ivalon Particles in Cases of Intracranial Meningiomas“. Neurologia medico-chirurgica 25, Nr. 2 (1985): 103–9. http://dx.doi.org/10.2176/nmc.25.103.

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