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Zeitschriftenartikel zum Thema „Intestine“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 25. Juli 2025

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1

Jaya, J. N., S. Novelina, J. Pamungkas, and Nurhidayat. "Morphological Characteristics of the Intestine of Cemani Chicken (Gallus gallus domesticus)." IOP Conference Series: Earth and Environmental Science 1359, no. 1 (2024): 012084. http://dx.doi.org/10.1088/1755-1315/1359/1/012084.

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Abstract This study was conducted with aim to tend out morphology of small intestine and large intestine of Cemani chicken at macroscopic and microscopic levels stained with Hematoxylin Eosin (HE). Samples were taken from intestines of three cemani chickens. The results showed that the length of the small and large intestine was 96.73±6.82 cm. The color of small intestine of the Cemani chicken was not completely black. The microscopic of intestinal wall were composed of four layers, tunica mucosa, tunica submucosa, tunica muscularis, and tunica serosa. Melanin pigment is distributed in the lam

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Borkovcova, Marie, Vladimir Fiser, Martina Bednarova, et al. "Effect of Accumulation of Heavy Metals in the Red Fox Intestine on the Prevalence of Its Intestinal Parasites." Animals 10, no. 2 (2020): 343. http://dx.doi.org/10.3390/ani10020343.

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The aim of this study was (i) to compare levels of accumulated heavy metals in the fox intestines with and without parasites. Moreover, our research also dealt with (ii) examination of the relationship between heavy metal content in fox intestines and between the presence of fox intestinal parasites. The intestines of 34 hunter-killed foxes were dissected to detect the occurrence of parasites. In 15 intestinal samples, parasitic intestinal helminths were found. Heavy metal content in small intestine tissue and in parasites was determined using atomic absorption spectrometry (AAS). The prevalen

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Kunisawa, Jun, Yosuke Kurashima, Morio Higuchi, et al. "Small and large intestinal intraepithelial T lymphocytes show distinct dependency on sphingosine 1-phosphate (42.11)." Journal of Immunology 178, no. 1_Supplement (2007): S35. http://dx.doi.org/10.4049/jimmunol.178.supp.42.11.

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Abstract It is known that the composition of intraepithelial T lymphocyte (IEL) differs between small and large intestines, but the mechanism underlying that difference remains obscure. Here, we show that sphingosine 1-phosphate (S1P) plays a key role in regulating intestinal IEL trafficking into the small and large intestines. High levels of type 1 S1P receptor (S1P1) expression was noted on naïve IELs expressing CD4 or CD8αβ, which leads to their preferential migration into the large intestine. In contrast, recent thymic emigrants (RTEs), double-positive thymocytes, and double-negative thym

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Hafid, Harapin, Nuraini Nuraini, Dian Agustina, Fitrianingsih Fitrianingsih, and Inderawati Inderawati. "Effect of Chicken Intestine Substitution to Chemical Quality of Nugget." ANIMAL PRODUCTION 19, no. 3 (2018): 207. http://dx.doi.org/10.20884/1.jap.2017.19.3.615.

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This research was aimed to study the chemical quality of the chicken nuggets substituted chicken intestine. The treatment was substitution of chicken meat with chicken intestine consisting of five levels was A0 (0% chicken intestine + 100% chicken meat), A1 (15% chicken intestine + 85% chicken meat), A2 (25% chicken intestine + 75% chicken meat ), A3 (40% chicken intestine + 60% chicken meat), A4 (50% chicken intestine + 50% chicken meat), A5 (65% chicken intestine + 35% chicken meat), A6 (75% chicken intestine + 25% chicken meat), A7 (90% chicken intestine + 10% chicken meat), and A8 (100% ch

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Mun, Jeongwon, Whan Hur, and Nam-On Ku. "Roles of Keratins in Intestine." International Journal of Molecular Sciences 23, no. 14 (2022): 8051. http://dx.doi.org/10.3390/ijms23148051.

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Keratins make up a major portion of epithelial intermediate filament proteins. The widely diverse keratins are found in both the small and large intestines. The human intestine mainly expresses keratins 8, 18, 19, and 20. Many of the common roles of keratins are for the integrity and stability of the epithelial cells. The keratins also protect the cells and tissue from stress and are biomarkers for some diseases in the organs. Although an increasing number of studies have been performed regarding keratins, the roles of keratin in the intestine have not yet been fully understood. This review fo

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Ptaszyńska, Aneta A., and Marek Gancarz. "Microsporidiosis Causing Necrotic Changes in the Honeybee Intestine." Applied Sciences 13, no. 8 (2023): 4957. http://dx.doi.org/10.3390/app13084957.

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Background: Microsporidia from the Nosema (Vairimorpha) genus are pathogenic fungi that complete their life cycle in the honeybee intestine. Therefore, the aim of this study was to determine the impact of the course of infection on the viability of honeybee intestine cells. Methods and Results: Intestines isolated from healthy and N. ceranae-infected honeybees were stained using two dyes, SYTO 9 and propidium iodide, and analyzed under an Axiovert 200M fluorescence microscope immediately after the isolation of the intestines. The ImageJ program was used for the quantitative analysis of the cel

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Costa, Marcello, Timothy James Hibberd, Lauren J. Keightley, et al. "Neural motor complexes propagate continuously along the full length of mouse small intestine and colon." American Journal of Physiology-Gastrointestinal and Liver Physiology 318, no. 1 (2020): G99—G108. http://dx.doi.org/10.1152/ajpgi.00185.2019.

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Cyclical propagating waves of muscle contraction have been recorded in isolated small intestine or colon, referred to here as motor complexes (MCs). Small intestinal and colonic MCs are neurogenic, occur at similar frequencies, and propagate orally or aborally. Whether they can be coordinated between the different gut regions is unclear. Motor behavior of whole length mouse intestines, from duodenum to terminal rectum, was recorded by intraluminal multisensor catheter. Small intestinal MCs were recorded in 27/30 preparations, and colonic MCs were recorded in all preparations ( n = 30) with sim

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Lozano, Luis-Fernando, Arthur A. Bickford, Anthony E. Castro, et al. "Association of Reoviridae Particles in an Enteric Syndrome of Poults Observed in Turkey Flocks during 1988." Journal of Veterinary Diagnostic Investigation 1, no. 3 (1989): 254–59. http://dx.doi.org/10.1177/104063878900100311.

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An enteric syndrome of turkey poults, characterized by enteritis, crop mycosis, intestinal changes (pale, thin-walled ballooning with watery contents), and rickets, occurred during 1988 in 74 turkey flocks from different farms belonging to 9 California turkey growers. The flocks ranged in size from 9,000 to 120,000 birds. Pools of intestine sections from 618 birds, representing 78 field cases, were examined. Histopathological examination of the intestines showed a mild to severe atrophy with a reduced depth of crypts, which was more prominent in the distal part of the small intestine. Viral is

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Sulyma, Volodymyr, and Olena Sulima. "Crohn's Disease – Disease for Immunologists, Proctologists, Gastroenterologists or Rheumatologists?" Eurasia Proceedings of Health, Environment and Life Sciences 5 (August 5, 2022): 84–87. http://dx.doi.org/10.55549/ephels.56.

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Crohn's Disease (CD) most commonly affects the terminal portion of the small intestine and the large intestine. CD can also affect any other part of the gastrointestinal tract, from mouth to anus. Inflammation of the intestines is usually not continuous, areas inflammation (foci of inflamed bowel) interspersed with normal areas intestines (segmental lesion). Depending on the severity of the inflammation the inner layer of the intestinal wall (mucosa) may turn red (erythematous) and swollen (edematous) with ulcers of different sizes and shapes (aphthae’s, superficial, deep, longitudinal), and t

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Nepomnyashchy, Valentin, Tamara Tamm, Ivan Mamontov, Olena Shakalova, Konstantin Kramarenko, and Andrey Ustinov6. "Histological Changes in the Intestinal Wall in Experimental Obstructive Ileus: Experimental Animal Study." Journal of Pioneering Medical Sciences 14, no. 04 (2025): 67–73. https://doi.org/10.47310/jpms2025140409.

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Background: Patients with obstructive bowel obstruction often develop severe infections, which can lead to death in 45-88% of cases. These complications are thought to be caused by bacteria in the intestine. However, treatments that affect these bacteria have not helped to reduce the number of complications. It is important to find other possible sources of infection in intestinal obstruction. The experiment was done to study how the intestinal wall changes during 48 hours of obstruction. Methods: The experiment was conducted on 13 white rats. The animals were separated into two groups. In the

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Marcelin, Glendie, and Margaret E. Conner. "The Neonate Fc Receptor (FcRn) For IgG Is Important For The Development of Rotavirus-Specific IgG Responses And Clearance of Rotavirus From The Intestines Of Mice (53.5)." Journal of Immunology 178, no. 1_Supplement (2007): S104. http://dx.doi.org/10.4049/jimmunol.178.supp.53.5.

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Abstract Rotavirus infection and virus-like particle vaccines induce intestinal rotavirus-specific IgG in mice that appears to play a role in protection. The mechanism by which rotavirus-specific IgG reaches the intestinal lumen is unknown. The neonatal Fc receptor for IgG (FcRn) is the only known transporter of IgG in the intestines in neonatal and adult mice. Additionally, FcRn is implicated in antigen presentation in the intestines of adult mice. We tested whether FcRn is important in protecting the intestine against rotavirus infection and in transport of rotavirus-specific IgG into the in

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Osawa, R., and PF Woodall. "A Comparative-Study of Macroscopic and Microscopic Dimensions of the Intestine in 5 Macropods (Marsupialia, Macropodidae) .2. Relationship With Feeding-Habits and Fiber Content of the Diet." Australian Journal of Zoology 40, no. 1 (1992): 99. http://dx.doi.org/10.1071/zo9920099.

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A comparative study of macroscopic and microscopic dimensions of the intestines in five macropod species indicated that the grazing macropods (the red kangaroo, Macropus rufus, and the eastern grey kangaroo, Macropus giganteus) had significantly longer caeca and large intestines than those of the browsing macropods (the swamp wallaby, Wallabia bicolor, and the red-necked pademelon, Thylogale thetis). This trend was not observed in the small intestine. The arid-adapted M. rufus also had a significantly longer large intestine than M. giganteus, which may be a water-conservation feature. Intestin

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Pechenikova, Victoria A., Anastasia S. Danilova, Victoria E. Kvarku, and Nadezhda N. Ramzaeva. "Intestinal endometriosis: features of clinical and morphological diagnostics." Bulletin of the Russian Military Medical Academy 23, no. 1 (2021): 41–50. http://dx.doi.org/10.17816/brmma63572.

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A clinical observation of the combined endometriotic lesion of the small intestine and the appendix is given below. Extragenital endometriosis is a rare pathology in which endometrioid heterotopies develop outside the reproductive system organs. At about 1825% of women suffering from the pelvic organs endometriosis, the intestines are involved in the pathological process. In this regard, it is believed that in most cases its lesion is secondary while the primary lesion of the intestine with endometriosis is rarely observed and occurs as a result of hematogenous introduction of endometrial elem

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Castillo-Azofeifa, David. "CHRONIC IFNΓ-DRIVEN INFLAMMATION IMPAIRS INTESTINAL TOLERANCE AND REGENERATION IN AGING". Innovation in Aging 7, Supplement_1 (2023): 260. http://dx.doi.org/10.1093/geroni/igad104.0865.

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Abstract The intestine’s remarkable regenerative capacity decreases with aging as the stem cellniche interaction is impaired. Beyond defects in the stem cell-niche interaction, there is a direct correlation between age-related changes in immunity and increased susceptibility to infections. However, how the aging immune system affects the regenerative capacity of the intestine to challenges such as infections is unclear. Here, we infected young and aged mice with Citrobacter rodentium, a model that activates the immune response and causes epithelial damage. Young mice successfully healed, while

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Voskoboynikov, Roman, and Justin R. DiAngelo. "The Role of the SR Protein 9G8 in the Drosophila Intestine to Regulate Lipid Metabolism." Lipidology 2, no. 1 (2025): 1. https://doi.org/10.3390/lipidology2010001.

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Background/Objectives: Metabolic diseases in humans, such as obesity or type 2 diabetes, arise from defects in the body’s ability to take in and store nutrients such as carbohydrates and triglycerides. Previous studies in the fruit fly, Drosophila melanogaster, have identified SR proteins, mRNA splicing factors that regulate splice-site selection, as regulating lipid storage in the fly fat body. However, whether SR proteins function in other tissues to regulate nutrient metabolism is not known. Methods: We focused on studying the role of SR proteins in intestines by decreasing their levels in

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Mifkovic, Andrej, Olia El Hassoun, Petra Lukacikova, Stanislav Malakhov, and Stefan Polák. "The Intestine – Anatomy, immunology, barrier function, microbiome and central regulations." European Journal of Anatomy 29, no. 2 (2025): 287–302. https://doi.org/10.52083/suqe1748.

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The intestine, with its complex anatomy and intricate physiology, plays a fundamental role in maintaining overall health and well-being. Understanding the diverse functions of the intestine and the factors that can disrupt them is crucial for preventing and managing a wide range of diseases and pathological conditions. This review article explores the multifaceted role of the intestine in regulating human health across physiological and pathological states. A systematic search for relevant literature was conducted using the following electronic databases: PubMed, Web of Science, Scopus, and Go

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Gulzoda, M. K., B. I. Safarov, K. R. Ruziboyzoda, and K. K. Kobilov. "Morphofunctional changes in the small intestine in acute adhesive small bowel obstruction." Health care of Tajikistan, no. 4 (February 15, 2023): 11–16. http://dx.doi.org/10.52888/0514-2515-2022-355-4-11-16.

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Aim: To study the features of morpho-functional changes in the small intestine mucosa in acute adhesive small bowel obstruction.Material and methods. The results of a comprehensive study of morphological and functional changes in the small intestine’s mucous membrane in 20 patients out of 50 with acute adhesive small intestinal obstruction were analyzed. Patients underwent resection of the small intestine with a biopsy from the mucous membrane, followed by a pathomorphological and biochemical examination of biopsy specimens.Results. The study results show that more pronounced pathomorphologica

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Zheng, Huiwen, Yanli Chen, Jing Li, et al. "Longitudinal analyses reveal distinct immune response landscapes in lung and intestinal tissues from SARS-CoV-2-infected rhesus macaques." Cell Reports 39, no. 8 (2022): 110864. https://doi.org/10.5281/zenodo.14822554.

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(Uploaded by Plazi for the Bat Literature Project) The pathological and immune response of individuals with COVID-19 display different dynamics in lung and intestine. Here, we depict the single-cell transcriptional atlas of longitudinally collected lung and intestinal tissue samples from SARS-CoV-2-infected monkeys at 3 to 10 dpi. We find that intestinal enterocytes are degraded at 3 days post-infection but recovered rapidly, revealing that infection has mild effects on the intestine. Crucially, we observe suppression of the inflammatory response and tissue damage related to B-cell and Paneth

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Eiji, Kobayashi. "A new stage of experimental surgery for organoid based intestinal regeneration – A review of organoid research and recent advance." Magyar Sebészet 75, no. 4 (2022): 261–64. http://dx.doi.org/10.1556/1046.2022.40002.

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AbstractSmall intestinal transplantation has emerged as an essential treatment for intestinal failure, but its relatively high graft rejection rate and mortality rate when compared to those of other transplanted organs has led to difficulties in post-transplantation treatment management. The recently-developed technique of creating organoids from somatic stem cells has created a challenging opportunity to develop a treatment that involves the creation of a substitute small intestine using autologous cells instead of transplanting another individual's small intestines. The remaining partial lar

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Yani, Ahmad, Dorothy Dorothy, and Rizky Amaliah. "Influence of Intestinal Strangulation Release on Ischemiareperfusion Injury in Sprague Dawley Rats." Annals of African Surgery 18, no. 2 (2021): 90–95. http://dx.doi.org/10.4314/aas.v18i2.6.

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Background: In intestinal ischemia, reperfusion towards the injured intestine can cause further injury to the intestine itself and to remote organs. This research aimed to evaluate the influence of intestinal strangulation release (SR) before resection on the intestine outside margin of the strangulated intestine compared with subjects without intestinal strangulation release (WSR). Methods: Fourteen male Sprague Dawley rats were subjected to strangulation of one loop of the distal ileum for 4 h. In the SR group, the strangulated intestine was released for 5 min and then resected for nec

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Yıldırım, Arda, Yüksel Aksoy, Nuh Ocak, and Zafer Ulutaş. "Some Gastrointestinal Tract Characteristics of Karayaka Ram Lambs Slaughtered at Different Weights." Scientific World Journal 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/379023.

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Thirty-one Karayaka ram lambs were slaughtered at different body weights (30n=7, 35n=6, 40n=7, 45n=6, and 50n=5 kg of body weight at fast) to evaluate the growth of their gastrointestinal tract (GIT) characteristics, to determine the relationship among slaughter body weight (SBW) and empty body weight (EBW), whole GIT and segments, and the influence of slaughter weight on the pH of rumen, jejunum, and cecal contents. The effects of the SBW on GIT weightP<0.05, stomachP<0.001, and intestineP<0.05, the body lengthP<0.001and caecumP<0.05, and the relative weights of GITP<0.05, s

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Grubb, B. R. "Ion transport across the normal and CF neonatal murine intestine." American Journal of Physiology-Gastrointestinal and Liver Physiology 277, no. 1 (1999): G167—G174. http://dx.doi.org/10.1152/ajpgi.1999.277.1.g167.

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Neonatal mice with cystic fibrosis (CF) exhibit a very high mortality due to intestinal obstruction localized primarily to the ileum and colon. It has been hypothesized that lack of Cl− secretion and possibly elevated Na+ absorption contribute to the gut problems in CF neonates. Therefore, intestines (ileum, proximal colon, and distal colon) from normal and CF day-old mouse pups were studied on ultra-small-aperture (0.0135 cm2) Ussing chambers. All three regions of the normal neonatal intestine responded to forskolin with an increase in short-circuit current, which was completely absent in the

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Gao, Yuqi, Qingxia Jin, Ce Gao, et al. "Unraveling Differential Transcriptomes and Cell Types in Zebrafish Larvae Intestine and Liver." Cells 11, no. 20 (2022): 3290. http://dx.doi.org/10.3390/cells11203290.

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The zebrafish intestine and liver, as in other vertebrates, are derived from the endoderm. Great effort has been devoted to deciphering the molecular mechanisms controlling the specification and development of the zebrafish intestine and liver; however, genome-wide comparison of the transcriptomes between these two organs at the larval stage remains unexplored. There is a lack of extensive identification of feature genes marking specific cell types in the zebrafish intestine and liver at 5 days post-fertilization, when the larval fish starts food intake. In this report, through RNA sequencing

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Ngo, Leock Y., Shivakumar D. Patil, and Jashvant D. Unadkat. "Ontogenic and longitudinal activity of Na+-nucleoside transporters in the human intestine." American Journal of Physiology-Gastrointestinal and Liver Physiology 280, no. 3 (2001): G475—G481. http://dx.doi.org/10.1152/ajpgi.2001.280.3.g475.

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The objectives of our study were to identify the types of nucleoside transporters present in the human fetal small intestine and to characterize their developmental activity, longitudinal distribution, and transport kinetics compared with those present in the adult intestine. Nucleoside uptake by intestinal brush-border membrane vesicles was measured by an inhibitor-stop rapid filtration technique. Only the purine-specific (N1; hCNT2) and the pyrimidine-specific (N2; hCNT1) Na+-dependent nucleoside transporters were found to be present on the brush-border membranes of the enterocytes along the

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White, N. A., D. E. Tyler, R. B. Blackwell, and D. Allen. "Hemorrhagic fibrinonecrotic duodenitis-proximal jejunitis in horses: 20 cases (1977–1984)." Journal of the American Veterinary Medical Association 190, no. 3 (1987): 311–15. https://doi.org/10.2460/javma.1987.190.03.311.

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Summary Records of 20 horses with small intestinal disease causing acute colic and affecting the proximal portion of the small intestine were examined retrospectively. The disease was characterized by severe to moderate pain, which was replaced by depression, fever, gastric reflux, slight distention of the affected small intestine, leukocytosis, and high concentrations of total protein in the peritoneal fluid. Grossly, the affected intestines were hemorrhagic and had yellow discoloration. Histopathologic findings included submucosal edema, neutrophilic infiltration of the submucosal and lamina

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SHINTOKU, Y., T. KADOSAKA, E. KIMURA, H. TAKAGI, S. KONDO, and M. ITOH. "Intestinal mast cells and eosinophils in relation to Strongyloides ratti adult expulsion from the small and large intestines of rats." Parasitology 140, no. 5 (2013): 626–31. http://dx.doi.org/10.1017/s0031182012001837.

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SUMMARYMucosal mast cells (MMC) play a crucial role in the expulsion of Strongyloides ratti adults from the small intestine of mice. We reported the large intestinal parasitism of S. ratti in rats, and there has been no report on MMC in the large intestine of the natural host. We studied kinetics of MMC, together with eosinophils, in the upper and lower small intestines, caecum and colon of infected rats. Two distinct phases of mastocytosis were revealed: one in the upper small intestine triggered by stimulation of ‘ordinary’ adults, and the other in the colon stimulated by ‘immune-resistant’

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Ma, Wenyao, Zhe Han, Xinlei Liu, et al. "Distinct Effects of Lactiplantibacillus plantarum HNU082 on Microbial Single-Nucleotide Variants in Large Intestine and Small Intestine." Microorganisms 13, no. 4 (2025): 731. https://doi.org/10.3390/microorganisms13040731.

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The intestinal tract extends several times the length of bodies, with varying environmental conditions across different segments (small intestinal and large intestinal), thereby harboring distinct gut microbiota. Most studies focused on the quantitative responses of gut microbiota upon probiotics entering the gut, without an in-depth analysis of how the genetic change in local gut microbiota. Therefore, in this experiment, C57BL/6J male mice were once administered Lactiplantibacillus plantarum HNU082 (Lp082). Then, the mice were euthanized on the 1st, 3rd, and 7th days after gavage, and the co

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Ngamkala, Suchanit, Khomson Satchasataporn, Chanokchon Setthawongsin, and Wuttinun Raksajit. "Histopathological study and intestinal mucous cell responses against Aeromonas hydrophila in Nile tilapia administered with Lactobacillus rhamnosus GG." May-2020 13, no. 5 (2020): 967–74. http://dx.doi.org/10.14202/vetworld.2020.967-974.

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Aim: This study aimed to examine the intestinal histopathological lesions and mucous cell responses in the entire intestines of Nile tilapia administered with Lactobacillus rhamnosus GG (LGG)-mixed feed, after Aeromonas hydrophila challenge. Materials and Methods: Intestinal samples from fish fed with control normal diet or LGG-mixed feed (1010 colony-forming unit [CFU]/g feed) with or without A. hydrophila in phosphate-buffered saline challenge (7.46 × 108 CFU/mL/fish) were collected and processed for histopathological study. The mucous cell responses were evaluated using histochemistry, usin

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Ikeda, T., T. Yoshida, M. Honda, et al. "Effect of intestinal factors on extraction of insulin in perfused rat liver." American Journal of Physiology-Endocrinology and Metabolism 253, no. 6 (1987): E603—E607. http://dx.doi.org/10.1152/ajpendo.1987.253.6.e603.

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To study the direct effect of intestinal factors on hepatic extraction of insulin, an investigation was made into the extraction of insulin from isolated rat liver perfused with portal venous effluent (PVE) obtained from the isolated perfused rat intestine. Rat intestine was perfused with Krebs-Ringer bicarbonate medium for 45 min, and the PVE was collected from glucose-, lipid-, or NaCl-treated and untreated control intestines. The PVE, after adjustment of its glucose (180 mg/dl) and insulin (200 microU/ml) concentrations, was used as the perfusing medium for the liver of a different rat. The

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Xu, Shi-Qi, Zheng-Yu Zhang, Bin Nie, Yi-Nan Du, Yue Tang, and Hai-Tao Wu. "Characteristics of the Intestine Extracts and Their Effect on the Crude Collagen Fibers of the Body Wall from Sea Cucumber Apostichopus japonicus." Biology 12, no. 5 (2023): 705. http://dx.doi.org/10.3390/biology12050705.

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Sea cucumbers Apostichopus japonicus will vomit their intestines during certain stimulations, and the collagen of the body wall will then be degraded. To define the effect of the sea cucumber intestine extracts on the body wall, the intestinal extracts and crude collagen fibers (CCF) of sea cucumber A. japonicus were prepared. According to the gelatin zymography, the type of endogenous enzymes in intestinal extracts were mainly serine endopeptidases with optimal activities at pH 9.0 and 40 °C. According to the rheology results, the viscosity of 3% CCF decreased from 32.7 Pa·s to 5.3 Pa·s by ad

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OESTERREICHER, J. Thomas, L. Lucy LEEPER, J. Milton FINEGOLD, J. Gretchen DARLINGTON та J. Susan HENNING. "Intestinal maturation in mice lacking CCAAT/enhancer-binding protein α (C/EPBα)". Biochemical Journal 330, № 3 (1998): 1165–71. http://dx.doi.org/10.1042/bj3301165.

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In rodents, there is a surge of intestinal expression of CCAAT/enhancer-binding protein α (C/EBPα) in the late fetal phase just before morphological maturation and the onset of expression of numerous epithelial genes. To investigate directly the hypothesis that C/EBPα plays a causal role in the latter phenomena, we have assessed both structural and functional maturation in neonatal intestine from C/EBPα-null mice and their littermates. No effects of C/EBPα genotype were observed on mucosal architecture or on the size of the proliferative zone in the intestinal crypts. Likewise, the mRNA levels

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Camerini, Victoria, Beate C. Sydora23, Richard Aranda, et al. "Generation of Intestinal Mucosal Lymphocytes in SCID Mice Reconstituted with Mature, Thymus-Derived T Cells." Journal of Immunology 160, no. 6 (1998): 2608–18. http://dx.doi.org/10.4049/jimmunol.160.6.2608.

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Abstract Transfer of peripheral lymph node lymphocytes to SCID mice leads to the long term establishment of mucosal T lymphocytes within the epithelium and lamina propria of the small and large intestines. Analysis of engrafted intraepithelial lymphocytes (IEL) showed that they had acquired a surface phenotype that in several respects is typical of IEL. In addition, the functional profile of engrafted IEL derived from lymph node T cells was similar to that of normal IEL; as the donor-derived T cells exhibited a strong cytolytic activity, a poor proliferative response to mitogenic stimuli, and

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Levy, Emile, Karine Trudel, Moise Bendayan, et al. "Biological role, protein expression, subcellular localization, and oxidative stress response of paraoxonase 2 in the intestine of humans and rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 293, no. 6 (2007): G1252—G1261. http://dx.doi.org/10.1152/ajpgi.00369.2007.

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Oxidative stress is a cardinal manifestation of various intestinal disorders. However, very little knowledge is available on the intestine's inherent defense mechanisms against free radicals. This study was designed to determine the protein expression, subcellular localization and oxidative stress response of paraoxonase 2 (PON2), a member of a powerful antioxidant family in human and rat intestine. Biochemical and ultrastructural experiments all showed a substantial expression of PON2 in human and rat intestine. Western blot analysis disclosed higher levels of PON2 in the jejunum than in the

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Qi, Zixin, Hongbo Ma, Li Ma, and Xuefen Yang. "The Structure of Digestive Tract Coordinating Digestion and Respiration in an Air-Breathing Weatherloach, Misgurnus anguillicaudatus." Biology 13, no. 6 (2024): 381. http://dx.doi.org/10.3390/biology13060381.

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To clarify how the digestive tract of the weatherloach, Misgurnus anguillicaudatus, serves a dual function of digestion and respiration simultaneously, the histological structures of its digestive tract, the passage of digesta and air passing through its intestine and the rate of intestinal evacuation have been studied. The results indicate that the digestive tract is divided into five functional regions, i.e., esophagus, anterior intestine, middle intestine, posterior intestine and rectum. The diverse intestinal structures have the specialized function of coordinating digestion and respiratio

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Tang, Chuang, Jideng Ma, Fanli Kong, et al. "The Analysis of Transcriptomes and Microorganisms Reveals Differences between the Intestinal Segments of Guinea Pigs." Animals 12, no. 21 (2022): 2925. http://dx.doi.org/10.3390/ani12212925.

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The intestine is a tubular organ with multiple functions such as digestion absorption and immunity, but the functions of each intestinal segments are different. Intestinal regionalization is necessary for normal physiological function, but it also means the research results obtained at specific sites may not be applicable to other intestinal segments. In order to comprehensively describe the functional changes in the intestine, different intestinal segments and their contents (duodenum, jejunum, ileum, cecum, colon, and rectum) of guinea pigs were collected for RNA seq and 16S rRNA seq, respec

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Permatasari, Febrina Dian, Poedji Hastutiek, and Lucia Tri Suwanti. "Kerusakan Usus pada Mencit (Mus musculus) yang Diinokulasi Larva 3 (L3) Anisakis spp." Jurnal Sain Veteriner 35, no. 1 (2017): 57. http://dx.doi.org/10.22146/jsv.29292.

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This study aims to be show damage in the intestine of mice caused by inoculation of the larvae of Anisakis spp. alive and who has died because of a warming 750C for 7 minutes. Eighteen male mice (Mus musculus) were divided into three groups: control group, a group of mice were inoculated the larvae of Anisakis spp. alive andgroups of mice were inoculated the larvae of Anisakis spp. who have died. 48 hours post inoculation, the mice’s intestines necropsy performed later performed HE staining to identify and scoring intestinal histopathology. The results showed inoculation of the larvae of Anisa

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Xiang, Hao, Jason Han, William E. Ridley, and Lloyd J. Ridley. "Chicken intestine: Intestinal tuberculosis." Journal of Medical Imaging and Radiation Oncology 62 (October 2018): 62. http://dx.doi.org/10.1111/1754-9485.10_12784.

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Schulte, Marc, and Michael Hensel. "Models of intestinal infection by Salmonella enterica: introduction of a new neonate mouse model." F1000Research 5 (June 24, 2016): 1498. http://dx.doi.org/10.12688/f1000research.8468.1.

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Salmonella entericaserovar Typhimurium is a foodborne pathogen causing inflammatory disease in the intestine following diarrhea and is responsible for thousands of deaths worldwide. Manyin vitroinvestigations using cell culture models are available, but these do not represent the real natural environment present in the intestine of infected hosts. Severalin vivoanimal models have been used to study the host-pathogen interaction and to unravel the immune responses and cellular processes occurring during infection. An animal model forSalmonella-induced intestinal inflammation relies on the pretr

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Burman, Andreanna, and Izumi Kaji. "Luminal Chemosensory Cells in the Small Intestine." Nutrients 13, no. 11 (2021): 3712. http://dx.doi.org/10.3390/nu13113712.

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In addition to the small intestine’s well-known function of nutrient absorption, the small intestine also plays a major role in nutrient sensing. Similar to taste sensors seen on the tongue, GPCR-coupled nutrient sensors are expressed throughout the intestinal epithelium and respond to nutrients found in the lumen. These taste receptors respond to specific ligands, such as digested carbohydrates, fats, and proteins. The activation of nutrient sensors in the intestine allows for the induction of signaling pathways needed for the digestive system to process an influx of nutrients. Such processes

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Bai, C., and D. P. Jones. "GSH transport and GSH-dependent detoxication in small intestine of rats exposed in vivo to hypoxia." American Journal of Physiology-Gastrointestinal and Liver Physiology 271, no. 4 (1996): G701—G706. http://dx.doi.org/10.1152/ajpgi.1996.271.4.g701.

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The effects of hypoxia on glutathione (GSH) concentration and GSH-related enzyme and transport systems were studied in the small intestine of rats exposed to 8-10 days of 10.5% O2. Exposure to hypoxia resulted in a 40% lower GSH concentration in enterocytes and a 50% lower concentration in blood plasma. Activities of GSH-related detoxication enzymes in the intestinal epithelium were largely unaffected by hypoxic exposure. GSH degradation and synthesis rates in enterocytes isolated from hypoxic rats were comparable with rates in normoxic controls, but GSH uptake rate was decreased by 30%. Stimu

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Tybinka, A. M. "Influence of autonomous regulation type on the connective tissue content in the muscular membrane of the chickens’ small intestine." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 26, no. 114 (2024): 43–52. http://dx.doi.org/10.32718/nvlvet11408.

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The relationship between the small intestine's muscular membrane structure of chickens and the autonomous regulation type was investigated. Based on electrocardiographic and variational pulsometric studies, adult laying hens of the Isa-Brown breed were divided into two groups: sympathotonic (ST) and sympatho-normotonic (ST-NT). The volume of individual layers and the entire muscle membrane, as well as the volume of connective tissue fibers located in it, was determined in the small intestine of the hens. In general, the relationship between morphological parameters and the autonomous regulatio

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Penn, Alexander H., and Geert W. Schmid-Schönbein. "The intestine as source of cytotoxic mediators in shock: free fatty acids and degradation of lipid-binding proteins." American Journal of Physiology-Heart and Circulatory Physiology 294, no. 4 (2008): H1779—H1792. http://dx.doi.org/10.1152/ajpheart.00902.2007.

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Shock and multiple organ failure remain primary causes of late-stage morbidity and mortality in victims of trauma. During shock, the intestine is subject to extensive cell death and is the source of inflammatory factors that cause multiorgan failure. We ( 34 ) showed previously that ischemic, but not nonischemic, small intestines and pancreatic protease digested homogenates of normal small intestine can generate cytotoxic factors capable of killing naive cells within minutes. Using chloroform/methanol separation of rat small intestine homogenates into lipid fractions and aqueous and sedimented

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Zhang, Wei, An Jiang, Haiyan Yu, and Bo Dong. "Comparative Transcriptomic Analysis Reveals the Functionally Segmented Intestine in Tunicate Ascidian." International Journal of Molecular Sciences 24, no. 7 (2023): 6270. http://dx.doi.org/10.3390/ijms24076270.

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The vertebrate intestinal system consists of separate segments that remarkably differ in morphology and function. However, the origin of intestinal segmentation remains unclear. In this study, we investigated the segmentation of the intestine in a tunicate ascidian species, Ciona savignyi, by performing RNA sequencing. The gene expression profiles showed that the whole intestine was separated into three segments. Digestion, ion transport and signal transduction, and immune-related pathway genes were enriched in the proximal, middle, and distal parts of the intestine, respectively, implying tha

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Ikeda, T., O. Mokuda, S. Kuno, Y. Tokumori, M. Tominaga, and H. Mashiba. "Enhanced intestinal insulinotropic effect in streptozotocin-diabetic rats." American Journal of Physiology-Endocrinology and Metabolism 248, no. 3 (1985): E304—E308. http://dx.doi.org/10.1152/ajpendo.1985.248.3.e304.

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To study the intestinal insulinotropic effects in the diabetic state, an investigation was made into the release of insulin from isolated rat pancreas perfused with portal venous effluent (PVE) obtained from the isolated perfused intestine of streptozotocin-induced diabetic rats. Rat intestine was perfused with Krebs-Ringer bicarbonate medium for 1 h, and the PVE was collected from both untreated and glucose-treated intestines of control and diabetic rats. The PVE, after adjusting its glucose concentration to the desired level, was used as the perfusing medium for the pancreas of a different r

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Snipes, RL, H. Snipes, and FN Carrick. "Morphometric data on the intestines of the platypus Ornithorhynchus anatinus and the short-beaked echidna Tachyglossus aculeatus." Australian Mammalogy 24, no. 2 (2002): 229. http://dx.doi.org/10.1071/am02229.

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ALTHOUGH the gross morphology of the monotreme gastrointestinal tract has been described (Griffiths 1978; Hume and Harrop 1980), morphometric data on the intestines of the two extant monotremes, the platypus (Ornithorhynchus anatinus) and the short-beaked echidna (Tachyglossus aculeatus), are to date incomplete. Using an established method (Snipes and Kriete 1991, Snipes 1994, 1995, 1997) to measure the entire intestines of mammals, which does not rely on extrapolations from measured probes with the inherent danger of missing major surfaceenlargement structures such as folds and villi, major m

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Plumb, Jane A., David Burston, Terry G. Baker, and Michael L. G. Gardner. "A comparison of the structural integrity of several commonly used preparations of rat small intestine in vitro." Clinical Science 73, no. 1 (1987): 53–59. http://dx.doi.org/10.1042/cs0730053.

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1. The structural integrities of various preparations of rat small intestine for the study of absorption in vitro have been compared after incubation or perfusion. 2. Perfused intestines removed from anaesthetized rats, and thus never deprived of a supply of oxygen, maintain their structural integrity even after perfusion for 1 h provided that a Krebs–Henseleit bicarbonate perfusate is used. However, intestines removed from freshly killed rats show severe villus disruption and oedema after perfusion for only 20 min. 3. Extensive damage to both crypts and villi is observed in everted sacs of sm

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Sharma, Latika, Harshit Srivastava, Dharmendra Kumar Pipal, Saurabh Kothari, Rohit Dhawan, and Poojan M. Purohit. "Acute intestinal obstruction: small intestine vs. large intestine: an analysis." International Surgery Journal 5, no. 1 (2017): 162. http://dx.doi.org/10.18203/2349-2902.isj20175888.

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Background: Bowel obstruction is one of the most common causes of acute abdomen and also a common surgical emergency.The causes of IO vary significantly depending on geographical location. The aim of this study was to identify the etiology, clinical presentation, management and outcomes of patients with acute mechanical IO presenting in Jodhpur, Rajasthan.Methods: A prospective study was conducted at Mahatma Gandhi Hospital and Mathura Das Mathur Hospital (associated with Dr. SN Medical College), Jodhpur, Rajasthan. 100 patients with acute intestinal obstruction were admitted and evaluated. Bl

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Collaco, Anne M., Peter Geibel, Beth S. Lee, John P. Geibel, and Nadia A. Ameen. "Functional vacuolar ATPase (V-ATPase) proton pumps traffic to the enterocyte brush border membrane and require CFTR." American Journal of Physiology-Cell Physiology 305, no. 9 (2013): C981—C996. http://dx.doi.org/10.1152/ajpcell.00067.2013.

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Vacuolar ATPases (V-ATPases) are highly conserved proton pumps that regulate organelle pH. Epithelial luminal pH is also regulated by cAMP-dependent traffic of specific subunits of the V-ATPase complex from endosomes into the apical membrane. In the intestine, cAMP-dependent traffic of cystic fibrosis transmembrane conductance regulator (CFTR) channels and the sodium hydrogen exchanger (NHE3) in the brush border regulate luminal pH. V-ATPase was found to colocalize with CFTR in intestinal CFTR high expresser (CHE) cells recently. Moreover, apical traffic of V-ATPase and CFTR in rat Brunner's g

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Gaoussou, Sogoba, Sangare Sidy, Traore Lamine Issaga, et al. "Left Paraduodenal Hernia: A Rare Cause of Intestinal Obstruction." SAS Journal of Surgery 7, no. 9 (2021): 489–90. http://dx.doi.org/10.36347/sasjs.2021.v07i09.004.

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We report the observation of a patient with acute intestinal obstruction by left para-duodenal hernia without necrosis of the incarcerated small intestines for one patient, treated by reduction of the incarcerated small intestine and resection of the hernial sac. We discuss in this case the diagnostic and therapeutic features of this rare condition.

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Tsimkhes, I. "On the function of the anastomosis between the small and large intestines." Kazan medical journal 25, no. 11 (2021): 1235. http://dx.doi.org/10.17816/kazmj80543.

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Tnnis (Dtsch. Z. f. Chir. Bd. 212. 1928) notes that in chronic obstipation the function of the anastomosis of the small intestine with the large intestine plays an important role. Often, due to antiperistaltic movements of the large intestine, the contents of the intestines can return or linger in the small intestine, making it difficult to empty the small intestine. The author recommends, based on the above considerations, to impose anastomosis end-to-side or end-to-end.

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