Auswahl der wissenschaftlichen Literatur zum Thema „Influenza équine“
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Zeitschriftenartikel zum Thema "Influenza équine"
Silva, R. A. M. S., A. M. R. Davila, L. B. Iversson und U. G. P. Abreu. „Maladies virales du cheval au Pantanal, Brésil. Etudes réalisées entre 1990 et 1995“. Revue d’élevage et de médecine vétérinaire des pays tropicaux 52, Nr. 1 (01.01.1999): 9–12. http://dx.doi.org/10.19182/remvt.9706.
Der volle Inhalt der QuelleKarim, Ouassa, und Soumaya El Hassouni. „Les conflits interpersonnels et l’interculturalité dans l’entreprise : une revue de littérature systématique“. Revue Congolaise de Gestion Numéro 36, Nr. 2 (22.11.2023): 92–141. http://dx.doi.org/10.3917/rcg.036.0092.
Der volle Inhalt der QuelleSemaï, Hakim, Amor Bouhdjar, Sofiane El Mokretar und Amel Boukadoum. „Influence du système de rebord sur le rendement d'un séchoir solaire“. Journal of Renewable Energies 15, Nr. 4 (25.10.2023): 589–97. http://dx.doi.org/10.54966/jreen.v15i4.348.
Der volle Inhalt der QuelleWiel, E., A. Facon, P. Mauriaucourt, D. Peucelle und P. Goldstein. „Régulation médicale: l'âge influence-t-il la décision d'envoi d'une équipe Smur?“ Journal Européen des Urgences 20, Nr. 1 (Mai 2007): 92–93. http://dx.doi.org/10.1016/j.jeur.2007.03.165.
Der volle Inhalt der QuelleMcGinn, Michelle K., und Ewelina K. Niemczyk. „Team Dynamics and Learning Opportunities in Social Science Research Teams“. Alberta Journal of Educational Research 66, Nr. 4 (24.12.2020): 364–86. http://dx.doi.org/10.55016/ojs/ajer.v66i4.56459.
Der volle Inhalt der QuelleLa Marne, Paula. „Tenir compte de la mort à l’école“. Diversité 189, Nr. 1 (2017): 97–102. http://dx.doi.org/10.3406/diver.2017.4478.
Der volle Inhalt der QuelleLebrument, Norbert, und Cédrine Zumbo-Lebrument. „L’implication des équipes de campagne électorale à l’épreuve de l’adoption de WhatsApp : conception et test d’un modèle appliqué aux élections municipales françaises de 2020“. Communication & management Vol. 20, Nr. 1 (02.05.2024): 39–65. http://dx.doi.org/10.3917/comma.203.0039.
Der volle Inhalt der QuelleJellad, A., S. Salah, M. A. Bouaziz, S. Boudokhane und Z. Ben Salah. „Influence psycho-comportementale et physiologique de la pratique du football dans une équipe féminine tunisienne“. Annals of Physical and Rehabilitation Medicine 54 (Oktober 2011): e125. http://dx.doi.org/10.1016/j.rehab.2011.07.626.
Der volle Inhalt der QuelleCZERNIAK, E., A. SPRIET, S. DURON, J.-B. . POHL, P. MAILLEUCHET und M. MONTEIL. „Prise de risque au cours des évacuations aériennes médicalisées : influence de l’équipe médicale ? Enquête par questionnaire au sein de l’aéronautique d’État“. Médecine et Armées Vol. 42 No. 2, Volume 42, Numéro 2 (01.04.2014): 141–46. http://dx.doi.org/10.17184/eac.6986.
Der volle Inhalt der QuelleBottaccioli, Francesco, und Anna Giulia Bottaccioli. „Risposta agli interventi di Mauro Fornaro e Piero Porcelli“. PSICOTERAPIA E SCIENZE UMANE, Nr. 2 (Mai 2024): 297–302. http://dx.doi.org/10.3280/pu2024-002006.
Der volle Inhalt der QuelleDissertationen zum Thema "Influenza équine"
Kleij, Lena. „Identification and validation of the virulence determinants of circulating equine influenza viruses“. Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL136.
Der volle Inhalt der QuelleInfluenza viruses are enveloped, their genome being segmented into 8 negative RNA segments. They are classified in the Orthomyxoviridae family. They are the etiological agents of the flu, a respiratory disease that affects many mammalian and avian species. Equine influenza is caused by the H3N8 and H7N7 subtypes of the type A influenza virus, the latter being extinct since the 1970s. Despite the existence of a vaccine, France has experienced several H3N8 epidemics since the 2000s. To reduce the significant economic impact of these epidemics for the equine industry, it is necessary to establish rapid, robust, and on-terrain applicable diagnostic tests to limit the circulation of the virus as much as possible and identify its virulence determinants as well as characterize antigenic drift.We studied the potential of the so-called “long read” sequencing technique developed by Oxford Nanopore Technologies. We carried out a characterization of the complete genome of two equine H3N8 viruses that circulated in France in 2009 and 2018 (A/equine/Paris/1/2018 and A/equine/Beuvron-en-Auge/2/2009, two viruses of clade 1 Florida) as well as the two strains of the vaccine commonly used in France.Our results demonstrated the reliability of this sequencing technique using amplicons of the eight genomic segments of the four viruses analyzed as well as the ability to produce reliable readings from direct sequencing of viral RNA (results presented in the first part). Analysis of the amino acid sequence of hemagglutinin HA of circulating strains demonstrated a very slight antigenic drift compared to vaccine strains with specific substitutions such as T161I in A/equine/Paris/1/2018 and N188T in the post-2015 strains, two substitutions located in the antigenic site B. The antigenic site E also shows modifications in the post-2018 strains, with the N63D substitution.Genomic segment 2 encodes one of the three subunits of the viral RNA polymerase, PB1, as well as an accessory protein, PB1-F2, of an alternative reading frame. PB1-F2 is recognized as a virulence determinant. While the A/equine/Paris/1/2018 strain encodes a variant 90 amino acids long, many strains, including A/equine/Beuvron-en-Auge/2/2009, encode a variant only 81 residues. Biological and biochemical tests were carried out to characterize the properties of each of these two forms of PB1-F2. In an assay where the long form of PB1-F2 is expressed in eukaryotic cells without other viral constituents, it abolishes the membrane potential of the cellular mitochondria. Placed in the presence of synthetic vesicles mimicking the mitochondrial outer membrane, the long form of PB1-F2 permeabilizes them more effectively than the short form. Amino acid sequence analyzes of the viral proteins (mainly HA and PB1-F2) are presented in a second part.In order to validate the impact of PB1-F2 on virulence in an infectious context, we sought to establish a reverse genetics system for the A/equine/Paris/1/2018 virus (third part). To do this, the 8 genomic segments were cloned into the pRF483 plasmid to ensure the synthesis of genomic RNA strands and the expression of viral proteins. The sequence of the inserts of each of the plasmids was validated. To validate the functioning of the replicative complex encoded by 4 of the 8 viral segments cloned in pRF483 (PA, PB1, PB2 and NP), these plasmids were transfected with a plasmid coding for the NA genomic segment in which its reading frame was substituted. by a reporter gene, luciferase. Under these experimental conditions, activity of the RNA-polymerase complex was detected. These tests will be extended for the production of recombinant viruses by transfection of the 8 constructed plasmids
Fougerolle, Stéphanie. „La grippe équine : détection moléculaire et caractérisation des souches de virus influenza : caractérisation de la réponse immunitaire après vaccination“. Caen, 2016. http://www.theses.fr/2016CAEN2067.
Der volle Inhalt der QuelleThe equine influenza virus (EIV) belongs to the family Orthomyxoviridae and is one of the most important equine respiratory pathogens, especially due to the economic losses associated with outbreaks. In horses, infection with the influenza virus causes significant morbidity. Mortality is uncommon and mostly associated with complications, such as secondary bacterial infections. Although there are vaccines since the 60’s, outbreaks, caused by the H3N8 subtype, are recorded around the world, including Sweden, Japan, Australia and France. Among the current issues related to EIV, this thesis focuses on both the pathogen and the host. , The molecular diversity of EIV strains and a possible link with virulence was investigated. This work involved a monitoring of EIV strains circulating in France and brought new notions about virulence mechanisms. The problem of low responder is a phenomenon accepted but not well understood in horses. The second aspect of this thesis was to study sub-optimal response to immunisation observed in some horses. The humoral immune response monitored, through the performance of SRH tests, in 202 foals during the primary course of vaccination against equine influenza. Results allowed to define the frequency of individuals that did not develop an adequate immune response and to highlight two independent factors playing a major role in the establishment of this sub-optimal response: the age of the foal and the presence of maternal antibodies at the time of first immunisation. In a preliminary study, evaluation of mRNA cytokines expression levels induced after EI immunization did not allow identification of intrinsic factors associated with low vaccination response
Carnet, Flora. „Amélioration des protocoles vaccinaux contre la grippe équine et la rhinopneumonie : apport de l’iPPVO en tant qu’adjuvant dans le modèle équin, nouvelle approche de la mesure des anticorps neutralisants“. Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMC413.
Der volle Inhalt der QuelleEquine influenza virus (EIV) and equine herpesvirus-1 (EHV-1) are frequently described in many countries and are two endemic pathogens in the French equine population. These infectious diseases have important consequences both in terms of animal health and welfare and in terms of economic impact. The fight against these viruses is essentially based on the implementation of preventive measures such as vaccination. Despite this epizootics of EIV and EHV-1 are regularly declared in France and throughout the world. Neutralising antibodies, synthesised in response to infection or after immunisation, represent the main line of defence against these viruses. Improved vaccines and a wider range of tools to measure neutralising antibodies can be a valuable strategy in the fight against these viruses. In order to improve the efficacy of the vaccine response, both in magnitude and duration, the use of adjuvants is one way to improve immunogenicity. This thesis consisted, in the first instance, in establishing the proof of concept of the use of iPPVO as an innovative adjuvant in vivo in horses in the context of vaccination against EIV. For this purpose, antibodies were measured by SRH, a method for which the correlates of protection are well defined. The addition of iPPVO at vaccination significantly increased the antibody level to EIV and protection in horses up to 6 months after immunisation. In a second step, a new method for measuring EIV antibodies in serum based on impedancemetry was developed to improve on current methods and facilitate high throughput analysis. This neutralisation test correlated well with SRH test. Another study was performed, which demonstrated the adjuvant potential of iPPVO in horses during vaccination against EHV-1,4. The antibody response measured by serum neutralisation increased up to 5 months after immunisation. Finally, preliminary results on the mechanism of action of iPPVO on peripheral blood mononuclear cells demonstrated the importance of the interferon
Legrand, Loïc. „Intérêt de l'étude moléculaire du gène de la protéine M pour la caractérisation du métapneumovirus humain et des virus influenza équins“. Caen, 2011. http://www.theses.fr/2011CAEN3130.
Der volle Inhalt der QuelleThe human metapneumovirus and equine influenza viruses, H3N8 subtypes, belong to the Paramyxoviridae and Orthomyxoviridae Family, respectively. The reported work evaluates the relevance of the M and M1 genes, coding for matrix protein, 1/ in detecting viral RNA by molecular genetic tools 2/ for phylogenetic purposes. For the hMPV, molecular genetic tools have been developed against the M gene because a study, the first detection of hMPV in France, was carried out using RT-PCR targeting the N gene. Since the tests being developed against the N gene did not allow the identification of all group of hMPV, a rRT-PCR following by a nested PCR were set up in the M gene and used to perform a phylogenetic characterization of hMPV strains circulating in Normandy between 2002 and 2005. All groups and subgroups of hMPV (A1, A2, B1 and B2) were detected. Subsequently, these methods were adapted to a multiplex detection tool, also including human respiratory syncytial virus and influenza virus A and B. Considering EIV, a real-time RT-PCR was developed in the M1 gene, which was used to detect EIV circulating in France between 2005 and 2010. Phylogenic analyses were also conducted even not in the M1 gene, which was insufficiently variable. H3 gene, encoding the major EIV surface protein, was used to determine the different variants. This study revealed for the first time in France the presence of an EIV American lineage, cluster Florida. Molecular genetic tools developed in M and M1 genes thus allowed the detection of both viruses. While Paramyxoviridae M gene only seems suitable for studying viral variability, H3 gene remains the most appropriate for EIV for this purpose
Moussa, Mohamad. „Influence du stade de développement de l’embryon équin sur son aptitude à la conservation par le froid“. Rennes, Agrocampus Ouest, 2005. http://www.theses.fr/2005NSARB165.
Der volle Inhalt der QuelleDifferent methods were used to evaluate in vitro and in vivo the embryo quality staining by DAPI, TUNEL, surgical transfer of paired embryos, and BdrU incorporation. Some of them were adapted for the first time to equine embryos. Aims of these studies were : 1) to test in vivo and in vitro different media for cold storage of equine embryos, different systems of transport and the influence of age and stage of development of embryos on their ability to be cold stored, 2) to evaluate the viability and the incidence of DNA fragmentation in D7 embryos after storage in different media at + 5°C, 3) to adapt the BrdU incorporation assay to equine embryos and to comparate the efficiency of cryopreservation for equine embryos using the slow-cooling and OPS (Open Pulled Straw) vitrification procedure. Main data of these were ; Emcare Holding Solution and ViGro Holding Plus offer a good alternative to Ham’s F10 for 24h cold storage of equine embryos. Cold-storage increases cell death by necrosis but does not induce apoptosis. Embryos stored in 500 ml of Emcare Flushing Solution at + 5°C for 6h had a better quality than after the traditional 24h-storage in an Equitainer. Index of cell proliferation, evaluated by an incubation in BrdU during one hour, is higher (74%) in equine D6. 5 embryos than in caprine embryos (38%). Vitrification using OPS system appears to be as effective as the slow cooling method. A significant correlation between the diameter of embryos recovered at 6. 5, 7 and 8 days and the total number of cells was established
Wicart, Philippe. „Initiation de la marche : influence de la latéralité et des défauts résiduels de pied bot varus équin congénital idiopathique unilatéral“. Paris 11, 2004. http://www.theses.fr/2004PA112335.
Der volle Inhalt der QuelleGaucher, Cécile. „Etude locale de l'hydrodynamique dans un module équipé d'une membrane plane d'ultrafiltration en céramique : influence de la contrainte pariétale sur le colmatage“. Nantes, 2001. http://www.theses.fr/2001NANT2073.
Der volle Inhalt der QuelleThis work focuses on the determination of local wall shear stress at the surface of a plane ceramic membrane in a tangential ultrafiltration module. In a first time, the shear stresses are determined at the surface of a plate of Plexiglas with the aim to investigate the best configuration of a plane tangential ultrafiltration module. The channel height and the shape of the distributors are studied so as to increased wall shear stress and thus to reduce the deposit of particles without increase the energy consumption. This analysis coupled with the Particle Image Velocity method (P. I. V. ) has allowed to characterise the flow to the surface of the plate of Plexiglas
Orard, Marie. „Influence du foin "à la vapeur" sur la réponse immune de chevaux asthmatiques : du challenge d'exposition (in vivo) à la stimulation (in vitro) des macrophages alvéolaires“. Thesis, Normandie, 2018. http://www.theses.fr/2018NORMC271/document.
Der volle Inhalt der QuelleEquine asthma is a recurrent obstructive disease of respiratory tract. Several aetiologic factors are known to induceor maintain the severe equine asthma (sEA), however the hay exposure is the main risk factor. The use of treatmentswith corticoids are effective in case of crisis, but ineffective in the absence of sanitary measures. So, since severalyears a device allowing to purify the hay with steam was developed, in order to decrease the dust content and themicrobiological antigens within the hay. The pathophysiology of sEA is complex. Among the main actors of thisimmune response, the alveolar macrophages have an important role in the intiatiation and orientation of the immuneresponse. So, investigating the role of the equine alveolar macrophages of sEA horses would allow to betterunderstand the initiation of the immune response in the sEA. In this context, we focused on the influence of steamedhay on the immune response of sEA horses during an in vivo challenge and an in vitro stimulation of the alveolarmacrophages. First, we studied the systematic and local responses of horses submitted to an in vivo challengeexposure to dry and steamed hay. The first part of this work allowed us to show a beneficial effect of the steamedhay on the mucus tracheal score of sEA horses, however we did not observe any beneficial effect of the steamed hayon the cytological and immune response. The second part of the study allowed us to investigate the response of thealveolar macrophages to steamed hay. The real time microscopy showed differences in the behavior of macrophagesin response (1) to various stimuli, (2) between sEA and CTL horses (3) between HDS resulting from dry hay or fromsteamed hay. Moreover, the protein quantification of IL-1β was signifantly higher and the concentration of IL-10significantly lower in AM supernatant of sEA horses compared to CTL. The TNF-α concentration was higher on AMafter in vitro stimulation in sEA and CTL horses. These results on the alveolar macrophages reponse after both invivo challenge and in vitro stimulation, can be used as a basis for future studies in order to further characterize therole of AM in case of sEA. This triple approach on the horse, the lung and the cell scale allows a global vision of theresponse to an exposure challenge to dry or steamed hay and allows having an optimistic preliminary look on the useof the steamed hay for sEA horses
Moukassi, Mohamed. „Influence du brassage du métal liquide sur le déroulement de la solidification des alliages métalliques : application à la formation de la zone équiaxe dans la coulée continue“. Vandoeuvre-les-Nancy, INPL, 1988. http://www.theses.fr/1988NAN10398.
Der volle Inhalt der QuelleDrogoul-Cogourdant, Carole. „Contribution à l'étude du fonctionnement de l'écosystème intestinal des équides : influence de la granulométrie du fourrage sur la digestion des parois végétales chez le poney en relation avec les modifications du transit et de l'activité fibrolytique des écosystèmes caelcal et colique“. Dijon, 2000. http://www.theses.fr/2000DIJOS043.
Der volle Inhalt der QuelleBücher zum Thema "Influenza équine"
Mansau, Andrée. La séduction: Donjuanismes européens et littératures émergentes : actes du séminaire de littérature comparée, Équipe littérature et herméneutique, Université de Toulouse II. Paris: Eurédit, 2010.
Den vollen Inhalt der Quelle findenDupont, Valérie. Tribus contemporaines: Explorations exotiques des artistes d'Occident : actes du colloque de Dijon, 5 et 6 mai 2000 : équipe d'accueil, mémoire, discours et images. Dijon: Editions universitaires de Dijon, 2002.
Den vollen Inhalt der Quelle findenBerichte der Organisationen zum Thema "Influenza équine"
Clark, Louise, Jo Carpenter und Joe Taylor. Des idées pour le travail d’influence : comprendre les chemins d’impact dans la réponse aux crises. Institute of Development Studies, Februar 2024. http://dx.doi.org/10.19088/core.2023.019.
Der volle Inhalt der QuelleGruber, Verena, Ingrid Peignier und Charlotte Dubuc. Pratiques et tactiques de vente des concessionnaires automobiles au Québec. CIRANO, Oktober 2023. http://dx.doi.org/10.54932/bryk4403.
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