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Thematische Bibliographien / Human-composed / Zeitschriftenartikel

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Zeitschriftenartikel zum Thema „Human-composed“

Autor: Grafiati

Veröffentlicht am 24. Juni 2021

Zuletzt aktualisiert am 5. Februar 2022

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1

Higazi, Abd Al-Roof, Andrew Mazar, Jieyi Wang, Nancy Quan, Robert Griffin, Regina Reilly, Jack Henkin und Douglas B. Cines. „Soluble Human Urokinase Receptor Is Composed of Two Active Units“. Journal of Biological Chemistry 272, Nr. 8 (21.02.1997): 5348–53. http://dx.doi.org/10.1074/jbc.272.8.5348.

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2

Régnier, M., A. Patwardhan, A. Scheynius und R. Schmidt. „Reconstructed human epidermis composed of keratinocytes, melanocytes and Langerhans cells“. Medical & Biological Engineering & Computing 36, Nr. 6 (November 1998): 821–24. http://dx.doi.org/10.1007/bf02518889.

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3

Steffens, Melanie, Friederike Göpel, Anaclet Ngezahayo, Carsten Zeilinger, Arne Ernst und Hans-Albert Kolb. „Regulation of connexons composed of human connexin26 (hCx26) by temperature“. Biochimica et Biophysica Acta (BBA) - Biomembranes 1778, Nr. 5 (Mai 2008): 1206–12. http://dx.doi.org/10.1016/j.bbamem.2008.01.016.

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4

Ogata, Akira, und Shinji Deguchi. „Novel Preparation of Grafts Composed of Human Alveolar Bone Periosteal Cells“. Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 48, Nr. 3 (2006): 192–200. http://dx.doi.org/10.2329/perio.48.192.

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5

Chopek, Michael W., Jean Pierre Girma, Kazuo Fujikawa, Earl W. Davie und Koiti Titani. „Human von Willebrand factor: a multivalent protein composed of identical subunits“. Biochemistry 25, Nr. 11 (03.06.1986): 3146–55. http://dx.doi.org/10.1021/bi00359a012.

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6

Dianzani, Ferdinando, Guido Antonelli, Elisabetta Riva, Ombretta Turriziani, Laura Antonelli, Stephen Tyring, Daniel A. Carrasco et al. „Is Human Immunodeficiency Virus RNA Load Composed of Neutralized Immune Complexes?“ Journal of Infectious Diseases 185, Nr. 8 (15.04.2002): 1051–54. http://dx.doi.org/10.1086/340043.

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7

Kurashige, Motoki, Kiyoshi Nishimoto und Tetsuya Miyoshi. „Human Machine Interface composed of Force Sensors for Omni-directional Vehicle“. Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2002 (2002): 77. http://dx.doi.org/10.1299/jsmermd.2002.77_4.

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8

Stoll, Christoph, Jelena L. Holovati, Jason P. Acker und Willem F. Wolkers. „Liposomes composed of unsaturated lipids for membrane modification of human erythrocytes“. Molecular Membrane Biology 28, Nr. 7-8 (Januar 2011): 454–61. http://dx.doi.org/10.3109/09687688.2011.622304.

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9

Djebali, Sarah, Julien Lagarde, Philipp Kapranov, Vincent Lacroix, Christelle Borel, Jonathan M. Mudge, Cédric Howald et al. „Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells“. PLoS ONE 7, Nr. 1 (04.01.2012): e28213. http://dx.doi.org/10.1371/journal.pone.0028213.

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10

Raglio, Alfredo, Paola Baiardi, Giuseppe Vizzari, Marcello Imbriani, Mauro Castelli, Sara Manzoni, Francisco Vico und Luca Manzoni. „Algorithmic Music for Therapy: Effectiveness and Perspectives“. Applied Sciences 11, Nr. 19 (23.09.2021): 8833. http://dx.doi.org/10.3390/app11198833.

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This study assessed the short-term effects of conventional (i.e., human-composed) and algorithmic music on the relaxation level. It also investigated whether algorithmic compositions are perceived as music and are distinguishable from human-composed music. Three hundred twenty healthy volunteers were recruited and randomly allocated to two groups where they listened to either their preferred music or algorithmic music. Another 179 healthy subjects were allocated to four listening groups that respectively listened to: music composed and performed by a human, music composed by a human and performed by a machine; music composed by a machine and performed by a human, music composed and performed by a machine. In the first experiment, participants underwent one of the two music listening conditions—preferred or algorithmic music—in a comfortable state. In the second one, participants were asked to evaluate, through an online questionnaire, the musical excerpts they listened to. The Visual Analogue Scale was used to evaluate their relaxation levels before and after the music listening experience. Other outcomes were evaluated through the responses to the questionnaire. The relaxation level obtained with the music created by the algorithms is comparable to the one achieved with preferred music. Statistical analysis shows that the relaxation level is not affected by the composer, the performer, or the existence of musical training. On the other hand, the perceived effect is related to the performer. Finally, music composed by an algorithm and performed by a human is not distinguishable from that composed by a human.

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11

Yang, Ming, Samuel K. Lai, Ying-Ying Wang, Weixi Zhong, Christina Happe, Michael Zhang, Jie Fu und Justin Hanes. „Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus“. Angewandte Chemie 123, Nr. 11 (18.02.2011): 2645–48. http://dx.doi.org/10.1002/ange.201006849.

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12

Yang, Ming, Samuel K. Lai, Ying-Ying Wang, Weixi Zhong, Christina Happe, Michael Zhang, Jie Fu und Justin Hanes. „Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus“. Angewandte Chemie International Edition 50, Nr. 11 (18.02.2011): 2597–600. http://dx.doi.org/10.1002/anie.201006849.

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13

Toman, P. David, Barbara M. Egbert, Jane A. Thomas und Frank A. DeLustro. „Development of a Novel Nonantigenic Dermal Implant Composed of Human Placental Collagen“. Plastic and Reconstructive Surgery 113, Nr. 3 (März 2004): 1015–20. http://dx.doi.org/10.1097/01.prs.0000105649.69434.ef.

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14

Lorenz, H. Peter, und Michael T. Longaker. „Development of a Novel Nonantigenic Dermal Implant Composed of Human Placental Collagen“. Plastic and Reconstructive Surgery 113, Nr. 3 (März 2004): 1021–23. http://dx.doi.org/10.1097/01.prs.0000110001.16789.01.

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15

Nejman, Deborah, Ilana Livyatan, Garold Fuks, Nancy Gavert, Yaara Zwang, Leore T. Geller, Aviva Rotter-Maskowitz et al. „The human tumor microbiome is composed of tumor type–specific intracellular bacteria“. Science 368, Nr. 6494 (28.05.2020): 973–80. http://dx.doi.org/10.1126/science.aay9189.

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Bacteria were first detected in human tumors more than 100 years ago, but the characterization of the tumor microbiome has remained challenging because of its low biomass. We undertook a comprehensive analysis of the tumor microbiome, studying 1526 tumors and their adjacent normal tissues across seven cancer types, including breast, lung, ovary, pancreas, melanoma, bone, and brain tumors. We found that each tumor type has a distinct microbiome composition and that breast cancer has a particularly rich and diverse microbiome. The intratumor bacteria are mostly intracellular and are present in both cancer and immune cells. We also noted correlations between intratumor bacteria or their predicted functions with tumor types and subtypes, patients’ smoking status, and the response to immunotherapy.

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Butt, Khalid Iqbal, Manabu Yamazaki und Motomu Manabe. „Ultrastructure of size-regulated hetero-spheroids composed of human keratinocytes and fibroblasts“. Journal of Dermatological Science 11, Nr. 3 (März 1996): 239–49. http://dx.doi.org/10.1016/0923-1811(95)00456-4.

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17

Butt, K. I., M. Manabe und H. Ogawa. „064 Size-regulated multicellular hetero-spherolds composed of human keratinocytes and fibroblasts“. Journal of Dermatological Science 10, Nr. 1 (Juli 1995): 73. http://dx.doi.org/10.1016/0923-1811(95)93778-y.

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18

Souto, Luís Ricardo Martinhão, Jussara Rehder, José Vassallo, Maria Letícia Cintra, Maria Helena Stangler Kraemer und Maria Beatriz Puzzi. „Model for human skin reconstructed in vitro composed of associated dermis and epidermis“. Sao Paulo Medical Journal 124, Nr. 2 (2006): 71–76. http://dx.doi.org/10.1590/s1516-31802006000200005.

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CONTEXT AND OBJECTIVE: The technique of obtaining human skin with dermis and epidermis reconstructed from cells isolated from patients can enable autologous skin grafting on patients with few donor sites. It also enables in vitro trials on chemicals and drugs. The objective of this work was to demonstrate a method for obtaining human skin composed of associated dermis and epidermis, reconstructed in vitro. DESIGN AND SETTING: Experimental laboratory study, in the Skin Cell Culture Laboratory of Faculdade de Ciências Médicas, Universidade Estadual de Campinas. METHODS: Cells from human fibroblast cultures are injected into bovine collagen type I matrix and kept immersed in specific culturing medium for fibroblasts. This enables human dermis reconstruction in vitro. On this, by culturing human keratinocytes and melanocytes, differentiated epidermis is formed, leading to the creation of human skin composed of associated dermis and epidermis, reconstructed in vitro. RESULTS: We showed that human skin composed of associated dermis and epidermis can be successfully reconstructed in vitro. It is histologically formed in the same way as human skin in vivo. Collagen tissue can be identified in the dermis, with cells and extracellular matrix organized in parallel to multilayer epidermis. CONCLUSIONS: It is possible to obtain completely differentiated human skin composed of associated dermis and epidermis, reconstructed in vitro, from injection of human fibroblasts into bovine collagen type I matrix and culturing of human keratinocytes and melanocytes on this matrix.

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19

Matous̆ková, E., D. Vogtová und R. Königová. „A recombined skin composed of human keratinocytes cultured on cell-free pig dermis“. Burns 19, Nr. 2 (April 1993): 118–23. http://dx.doi.org/10.1016/0305-4179(93)90032-4.

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20

Stockman, J. A. „The New Pentavalent Rotavirus Vaccine Composed of Bovine (Strain WC3) -Human Rotavirus Reassortants“. Yearbook of Pediatrics 2008 (Januar 2008): 269–70. http://dx.doi.org/10.1016/s0084-3954(08)70421-4.

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Clark, H. Fred, Paul A. Offit, Stanley A. Plotkin und Penny M. Heaton. „The New Pentavalent Rotavirus Vaccine Composed of Bovine (Strain WC3) -Human Rotavirus Reassortants“. Pediatric Infectious Disease Journal 25, Nr. 7 (Juli 2006): 577–83. http://dx.doi.org/10.1097/01.inf.0000220283.58039.b6.

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22

Yamazaki, Manabu, Michiko Tsuchida, Ken-yu Kobayashi, Toshiaki Takezawa und Yuichi Mori. „A novel method to prepare size-regulated spheroids composed of human dermal fibroblasts“. Biotechnology and Bioengineering 44, Nr. 1 (05.06.1994): 38–44. http://dx.doi.org/10.1002/bit.260440107.

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23

Sakuma, Shinji, Rika Sudo, Norio Suzuki, Hiroshi Kikuchi, Hideo Takamori, Toshiyuki Sato, Yoshiharu Minamitake et al. „Human Calcitonin Delivered Orally by Means of Nanoparticles Composed of Novel Graft Copolymers“. Journal of Dispersion Science and Technology 24, Nr. 3-4 (07.01.2003): 623–32. http://dx.doi.org/10.1081/dis-120021819.

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24

Lee, Wen-Yu, Hung-Wen Tsai, Jen-Hao Chiang, Shiaw-Min Hwang, Ding-Yuan Chen, Li-Wen Hsu, Yi-Wen Hung, Yen Chang und Hsing-Wen Sung. „Core–shell cell bodies composed of human cbMSCs and HUVECs for functional vasculogenesis“. Biomaterials 32, Nr. 33 (November 2011): 8446–55. http://dx.doi.org/10.1016/j.biomaterials.2011.07.061.

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25

Hazan, Jamilé, Christopher Dubay, Marie-Pascale Pankowiak, Noëlle Becuwe und Jean Weissenbach. „A genetic linkage map of human chromosome 20 composed entirely of microsatellite markers“. Genomics 12, Nr. 2 (Februar 1992): 183–89. http://dx.doi.org/10.1016/0888-7543(92)90364-x.

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26

Kimura, Takuya, Ryuichi Shinohara, Christoph Böttcher und Teruyuki Komatsu. „Core–shell clusters of human haemoglobin A and human serum albumin: artificial O2-carriers having various O2-affinities“. Journal of Materials Chemistry B 3, Nr. 30 (2015): 6157–64. http://dx.doi.org/10.1039/c5tb00540j.

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Core–shell clusters composed of human haemoglobin A and human serum albumin having various O₂-affinities have been synthesized as potential O₂-carriers designed as red blood cell substitutes.

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27

SUZUKI, Maiko, Hiroshi AIZAWA und Naoko TAKAHASHI. „THE SOCIAL UNITS COMPOSED OF FUNCTIONS, SPATIAL SPHERES AND HUMAN RELATIONS OF A COMMUNITY“. Journal of Architecture and Planning (Transactions of AIJ) 67, Nr. 552 (2002): 199–206. http://dx.doi.org/10.3130/aija.67.199_1.

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28

Yoshizato, Katsutoshi, Chise Tateno und Rie Utoh. „Mice with Liver Composed of Human Hepatocytes as an Animal Model for Drug Testing“. Current Drug Discovery Technologies 9, Nr. 1 (01.03.2012): 63–76. http://dx.doi.org/10.2174/157016312799304570.

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29

Kondo, Seiji, Shouji Nakatsu, Harumi Sakahara, Hisataka Kobayashi, Junji Konishi und Yuziro Namba. „Antitumour activity of an immunoconjugate composed of anti-human astrocytoma monoclonal antibody and neocarzinostatin“. European Journal of Cancer 29, Nr. 3 (Januar 1993): 420–23. http://dx.doi.org/10.1016/0959-8049(93)90399-z.

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Altland, Klaus, und Pia Winter. „Human plasma transthyretin (TTR) is composed of many different molecular species with modifiable stability“. Neuromuscular Disorders 6 (Februar 1996): S15. http://dx.doi.org/10.1016/0960-8966(96)88815-8.

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31

Hajdú, Tibor, Tamás Juhász, Csilla Szűcs-Somogyi, Kálmán Rácz und Róza Zákány. „NR1 and NR3B Composed Intranuclear N-methyl-d-aspartate Receptor Complexes in Human Melanoma Cells“. International Journal of Molecular Sciences 19, Nr. 7 (30.06.2018): 1929. http://dx.doi.org/10.3390/ijms19071929.

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32

Kinoshita, M., Y. Okamoto, M. Furuya und M. Okamoto. „Biocomposites composed of natural rubber latex and cartilage tissue derived from human mesenchymal stem cells“. Materials Today Chemistry 12 (Juni 2019): 315–23. http://dx.doi.org/10.1016/j.mtchem.2019.03.002.

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Harada, Yoshifumi, Yutaka Mifune, Takeshi Kokubu, Atsuyuki Inui, Tomoyuki Muto, Fumiaki Takase, Issei Nagura und Masahiro Kurosaka. „Rat rotator cuff repair using a cell sheet composed of human rotator cuff derived cells“. Journal of Shoulder and Elbow Surgery 23, Nr. 5 (Mai 2014): 601. http://dx.doi.org/10.1016/j.jse.2014.01.022.

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ZHANG, JUN, JIANMIN YANG, YUAN CAI, NI JIN, HUIJU WANG und TONG YU. „Multiple antigenic polypeptide composed of heparanase B-cell epitopes shrinks human hepatocellular carcinoma in mice“. Oncology Reports 33, Nr. 3 (18.12.2014): 1248–56. http://dx.doi.org/10.3892/or.2014.3679.

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35

Landini, Nicolò, Gabriele Anania, Barbara Fabbri, Andrea Gaiardo, Sandro Gherardi, Vincenzo Guidi, Giorgio Rispoli, Lucia Scagliarini, Giulia Zonta und Cesare Malagù. „Neoplasms and metastasis detection in human blood exhalations with a device composed by nanostructured sensors“. Sensors and Actuators B: Chemical 271 (Oktober 2018): 203–14. http://dx.doi.org/10.1016/j.snb.2018.05.102.

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36

Zakhem, Elie, Mostafa Elbahrawy, Giuseppe Orlando und Khalil N. Bitar. „Successful implantation of an engineered tubular neuromuscular tissue composed of human cells and chitosan scaffold“. Surgery 158, Nr. 6 (Dezember 2015): 1598–608. http://dx.doi.org/10.1016/j.surg.2015.05.009.

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Gomes, José Álvaro Pereira, Bábyla Geraldes Monteiro, Gustavo Barreto Melo, Ricardo Luiz Smith, Marcelo Cavenaghi Pereira da Silva, Nelson Foresto Lizier, Alexandre Kerkis, Humberto Cerruti und Irina Kerkis. „Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Human Immature Dental Pulp Stem Cells“. Investigative Opthalmology & Visual Science 51, Nr. 3 (01.03.2010): 1408. http://dx.doi.org/10.1167/iovs.09-4029.

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Mahowald, M. A., F. E. Rey, H. Seedorf, P. J. Turnbaugh, R. S. Fulton, A. Wollam, N. Shah et al. „Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla“. Proceedings of the National Academy of Sciences 106, Nr. 14 (24.03.2009): 5859–64. http://dx.doi.org/10.1073/pnas.0901529106.

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Drewe, John A., Jie-Sheng Chen, Antonio A. Reyes und Nancy C. Lan. „stable high expression of human gamma-aminobutyric acida receptors composed of alpha and beta subünitS“. Life Sciences 57, Nr. 12 (August 1995): 1175–82. http://dx.doi.org/10.1016/0024-3205(95)02063-o.

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Pitto, M., P. Palestini, A. Ferraretto, M. Marazzi, V. Donati, L. Falcone und M. Masserini. „Interaction of liposomes composed of phospholipids, GM1 ganglioside and cholesterol with human keratinocytes in culture“. Archives of Dermatological Research 291, Nr. 4 (09.04.1999): 232–37. http://dx.doi.org/10.1007/s004030050399.

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Liu, Yunsong, Yongsheng Zhou, Hailan Feng, Gui-e. Ma und Yongwei Ni. „Injectable tissue-engineered bone composed of human adipose-derived stromal cells and platelet-rich plasma“. Biomaterials 29, Nr. 23 (August 2008): 3338–45. http://dx.doi.org/10.1016/j.biomaterials.2008.04.037.

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42

Chen, Hao, Fang Wang, Jian Guo Zhang, Yan Ping Guo und Hai Yan Song. „A Human Finite Element Model for Human-Cushion Interface Pressure Research“. Applied Mechanics and Materials 291-294 (Februar 2013): 2715–18. http://dx.doi.org/10.4028/www.scientific.net/amm.291-294.2715.

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The aim of the present work was to develop a lain-human finite element model for cushion design to prevent bedsore by performing biomechanical analysis on interface pressure. The geometric data of the human was obtained by laser scans. The finite element model was composed of solid hexahedral elements. The material of the bed cushions was obtained according to the mechanical experiment. The human model was validated by comparing the simulation result with the experimental data. The validated finite element model could be used to facilitate, accelerate and economize the process of design of cushion.

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Feng, Feifei, Yongli Yang, Zhitao Li, Jinyan Song, Hansong Zhu, Lixia Wang, Yong Zhao et al. „Changes in telomere length and telomerase activity in human bronchial epithelial cells induced by coal tar pitch extract“. Toxicology Research 4, Nr. 6 (2015): 1535–44. http://dx.doi.org/10.1039/c5tx00121h.

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Fender, P., G. Schoehn, J. Foucaud-Gamen, E. Gout, A. Garcel, E. Drouet und J. Chroboczek. „Adenovirus Dodecahedron Allows Large Multimeric Protein Transduction in Human Cells“. Journal of Virology 77, Nr. 8 (15.04.2003): 4960–64. http://dx.doi.org/10.1128/jvi.77.8.4960-4964.2003.

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ABSTRACT Adenovirus dodecahedron is a virus-like particle composed of only two viral proteins of human adenovirus serotype 3 that are responsible for virus attachment and internalization. We show here that this dodecameric particle, devoid of genetic information, efficiently penetrates human cells and can deliver large multimeric proteins such as immunoglobulins.

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YANG, HUA, YING QIU, XIANGHUI ZENG, YAN DING, JIANYE ZENG, KEHUAN LU und DONGSHENG LI. „Effect of a feeder layer composed of mouse embryonic and human foreskin fibroblasts on the proliferation of human embryonic stem cells“. Experimental and Therapeutic Medicine 11, Nr. 6 (30.03.2016): 2321–28. http://dx.doi.org/10.3892/etm.2016.3204.

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Shearer, Michael H., Robyn D. Dark, James Chodosh und Ronald C. Kennedy. „Comparison and Characterization of Immunoglobulin G Subclasses among Primate Species“. Clinical Diagnostic Laboratory Immunology 6, Nr. 6 (01.11.1999): 953–58. http://dx.doi.org/10.1128/cdli.6.6.953-958.1999.

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ABSTRACT Little information is available on the immunoglobulin G (IgG) subclasses expressed in the sera of nonhuman primate species. To address this issue, we compared the IgG subclasses found in humans (IgG1, IgG2, IgG3, and IgG4) to those of nonhuman primates, such as baboons and macaques. Cross-reactive antihuman IgG subtype-specific reagents were identified and used to analyze purified IgG from sera by solid-phase enzyme-linked immunosorbent assay. Protein A-purified human IgG obtained from sera was composed of IgG1, IgG2, IgG3, and IgG4, whereas baboon and macaque IgG was composed of IgG1, IgG2, and IgG4. Protein G-purified human IgG was composed of IgG1, IgG2, IgG3, and IgG4, whereas baboon and macaque IgG was composed of IgG1, IgG2, and IgG4. To test the possibility that baboon and macaque IgG3 is actually present, but is outcompeted for binding to proteins A and G by the other more abundant IgG subclasses, we repurified the IgG from sera that did not bind either protein A or protein G. We found a baboon IgG3 population in the sera that did not bind protein A, but bound protein G. No IgG3 subtype was detectable in macaque sera. These data suggest that baboon sera, like human sera, contain four IgG subtypes, whereas macaque sera exhibit only three of the human subclass analogs. In addition, the IgG subtype-specific reagents were shown to be useful in determining the IgG subclass distribution following vaccination of baboons with hepatitis B surface antigen.

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Kajander, E. O., L. I. Kauppinen, R. L. Pajula, K. Karkola und T. O. Eloranta. „Purification and partial characterization of human polyamine synthases“. Biochemical Journal 259, Nr. 3 (01.05.1989): 879–86. http://dx.doi.org/10.1042/bj2590879.

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Spermidine synthase was purified to apparent homogeneity from human spleens (8700-fold) by affinity chromatography. The native enzyme was composed of two subunits of identical Mr (35,000) and showed an apparent Mr of 62,000 in pore-gradient gel electrophoresis. Its pI was 5.1, Spermine synthase was purified to apparent homogeneity from placenta (5300-fold) and from kidney (4600-fold). The native enzyme was composed of two subunits of identical Mr (45,000) and showed an apparent Mr of 78,000 in pore-gradient gel electrophoresis. In isoelectric focusing it revealed two bands, with pI values of 4.9 and 5.0. Both synthases were present in all human tissues studied, but revealed a clear tissue-specific pattern. Mouse antisera against spermidine synthase revealed only one band, of Mr 35,000, in all purified enzyme preparations and in crude human tissue extracts in immunoblotting. Antisera against spermine synthase showed an immunoreactive band corresponding to the Mr of the subunit of spermine synthase. These antisera did not indicate any cross-reactivity in immunoblotting. Thus spermine synthase and spermidine synthase do not share homologous antigenic sites and are totally different proteins.

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ASANO, Haruhiko, Takashi MURATE, Tomoki NAOE, Hidehiko SAITO und George STAMATOYANNOPOULOS. „Molecular cloning and characterization of ZFF29: a protein containing a unique Cys2His2 zinc-finger motif“. Biochemical Journal 384, Nr. 3 (07.12.2004): 647–53. http://dx.doi.org/10.1042/bj20040394.

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We have cloned a gene, ZFF29 (zinc-finger protein of human fetal liver erythroid cells 29), from human fetal liver erythroid cells. Two types of mature mRNA were identified and designated ZFF29a and ZFF29b. In human genome the ZFF29 gene is on chromosome 9q, and the two forms are splice variants. There is a unique transcription start site, which predicts major mRNAs composed of 2485 bases for ZFF29a and 1801 bases for ZFF29b. The anticipated mRNAs were demonstrated in K562 cells, but not in any adult human tissues examined by Northern blotting. In the mouse, reverse transcription–PCR revealed that the ZFF29 mRNA is present in adult bone marrow and ovary at a higher level than in any other tissues examined. These findings suggest that ZFF29 proteins are expressed in embryonic/fetal erythroid tissues. The deduced polypeptide chains of ZFF29a and ZFF29b are composed of 306 and 350 amino acids respectively. A unique zinc-finger motif composed of two contiguous Cys2His2-type fingers is common to both forms of ZFF29. They are nuclear proteins and ZFF29b, but not ZFF29a, is an activator of erythroid gene promoters.

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Fong, Hanson, und Mehmet Sarikaya. „Nanoscale Correlation of Structure and Mechanical Properties of a Human Tooth“. Microscopy and Microanalysis 4, S2 (Juli 1998): 942–43. http://dx.doi.org/10.1017/s1431927600024831.

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The human tooth is a functionally-gradient structural composite material composed of collagen and hydroxyapatite (HAP). The outer most region is a hard enamel layer consisting primarily of HAP. Underneath is dentin region, which is composed of HAP with a significant fraction of collagen fibers. It has been demonstrated that it is possible to perform nano-indentation on sub-micron regions of tooth using either a standard nanoindentor or modified cantilever type atomic force microscope tip (AFM). In this study, we report nano-mechanical properties of dentin and enamel regions of a human tooth, measured with a nanoindentor attached to an AFM using a vertical force, in correlation with the microstructures observed with TEM.TEM and nano-indentation samples were prepared from a juvenile human incisor tooth. The tooth was first sectioned into 1 mm thick slices along its length, each containing both dentin and enamel regions. A slice was taken to prepare a TEM sample and an adjacent slice was used for nano-indentation measurements.

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Roy, Ananda L., und Richard S. Conroy. „Toward mapping the human body at a cellular resolution“. Molecular Biology of the Cell 29, Nr. 15 (August 2018): 1779–85. http://dx.doi.org/10.1091/mbc.e18-04-0260.

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The adult human body is composed of nearly 37 trillion cells, each with potentially unique molecular characteristics. This Perspective describes some of the challenges and opportunities faced in mapping the molecular characteristics of these cells in specific regions of the body and highlights areas for international collaboration toward the broader goal of comprehensively mapping the human body with cellular resolution.

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