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1

Martindill, David Michael John. „Developmental regulation of Hand1 via nucleolar sequestration“. Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444458/.

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The bHLH transcription factor Hand1 is essential for placentation and cardiac morphogenesis in the developing embryo. However, how the activity of Hand1 is regulated in either lineage remains largely unknown. Here we demonstrate that Hand1 is anchored in the nucleolus and negatively-regulated by the murine orthologue of the human I-mfa domain-containing protein (HIC). Nucleolar sequestration controls Hand1 activity during the differentiation of rat choriocarcinoma-1 (Rcho-1) trophoblast cells. Hand1 is sequestered in the nucleoli of Rcho-1 stem cells but is released into the nucleoplasm at the onset of their differentiation into trophoblast giant cells. Site-specific phosphorylation of Hand1 was previously shown to modulate the affinity of Hand1 for its nucleoplasm E-factor binding partners. We demonstrate that Hand1 phosphorylation is required for its nucleolar release, as a pre-requisite for dimerisation and biological function. Moreover, the polo-like kinase Plk4 (Sak) is responsible for this phosphorylation event. Plk4 localises to the nucleolus of Rcho-1 stem cells at phase G2 and interacts with Hand1 in vitro and in vivo to promote mitotic cell cycle exit and entry into the endocycle. We also demonstrate that the B568 subunit of the PP2A phosphatase, shown previously to target Hand1 for dephosphorylation, is exported from the nucleus during Rcho-1 differentiation. In this thesis we present findings that describe a novel mode of Hand1 regulation that is a crucial step in trophoblast stem cell differentiation and placentation and support previous studies that implicate the nucleolus as a molecular 'sink'. We suggest that nucleolar sequestration is an important mode of protein regulation and this may impact on a broad range of transcription factors.
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Risebro, Catherine Ann. „The role of Hand1 in cardiac morphogenesis“. Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445824/.

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Handl encodes a bHLH transcription factor, which is essential for both placentation and cardiac morphogenesis during murine development. Extraembryonic defects in homozygous mutant embryos have precluded detailed analysis of Handl function in the heart. To circumvent the Handl-null early lethality and gain insight into the precise function of Handl during vertebrate heart development the bimodal tetracycline (Tet- Off) system has been employed to generate temporally controlled loss of function and gain of function models for Handl. The Tet-Off system comprises a tet-off transactivator and tet response element (responder) whereby transactivation of the responder and gene of interest can be switched off following addition of doxycycline. The transactivator has been targeted to the endogenous Handl locus {Tet-Off Handl) ensuring it is expressed in a spatial and temporal pattern consistent with the endogenous gene and generated transgenic lines for the responder (Tre2-Handl). Compound heterozygotes in either Handl-null or wild type backgrounds enable us to temporally switch off or over-express Handl respectively. Transactivator and responder constructs for gene targeting and transgenics respectively have been tested extensively in vitro, and sent to a commercial company to generate the mouse strains. Germline transmission was achieved for both Tet-Off-Handl and two transgenic Tre2-Handl strains. The Tre2-Handl responder lines failed to express Handl at a level suitable to rescue the mutant phenotype when crossed with the Tet-Off- Handl driver on a Handl-null background thus preventing further manipulation via dox administration to pregnant mothers to turn off Handl at different embryonic stages. However, a third line suitably expressed Handl under the tet-system and is currently being crossed with the driver for determining rescue as a first step towards validating the loss of function model. The transactivator and responder lines have also been crossed to generate mice that over-express Handl. At E9.5, embryos that over-express Handl have an extended outflow tract, convoluted looping of the linear heart tube and a small, thick-walled ventricle, which lacks a defined lumen. Marker analysis reveals inappropriate cardiomyocyte differentiation and an over-proliferation in the affected areas with a lack of ballooning in the presumptive left ventricle. In vitro differentiation studies have also been performed in ES cell lines that stably and precociously over-express Handl to complement the in vivo model.
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Courtney, Jennifer A. „The Role of Abnormal Placentation in Congenital Heart Defects“. University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1623165569297281.

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Togi, Kiyonori. „A role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart“. Kyoto University, 2004. http://hdl.handle.net/2433/145274.

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Chandrasekhar, Chaya. „Påla-period Buddha images their hands, hand gestures, and hand-held attributes /“. Connect to this title online, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1092830047.

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Thesis (Ph. D.)--Ohio State University, 2004.
Document formatted into pages; contains xvi,375 p.; also contains graphics. Includes bibliographical references. Abstract available online via OhioLINK's ETD Center; full text release delayed at author's request until 2009 Aug. 18.
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Chandrasekhar, Chaya. „Pāla-Period Buddha Images: their hands, hand gestures, and hand-held attributes“. The Ohio State University, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=osu1092830047.

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Kontoudis, Georgios Pantelis. „Adaptive, Anthropomorphic Robot Hands for Grasping and In-Hand Manipulation“. Thesis, Virginia Tech, 2019. http://hdl.handle.net/10919/87404.

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This thesis presents the design, modeling, and development of adaptive robot hands that are capable of performing dexterous, in-hand manipulation. The robot hand comprises of anthropomorphic robotic fingers, which employ an adaptive actuation mechanism. The mechanism achieves both flexion/extension and adduction/abduction, on the finger's metacarpophalangeal joint, by using two actuators. Moment arm pulleys are employed to drive the tendon laterally, such that an amplification on the abduction motion occurs, while also maintaining the flexion motion. Particular emphasis has been given to the modeling and the analysis of the actuation mechanism. Also, a model for spatial motion is provided that relates the actuation modes with the finger motion and the tendon force with the finger characteristics. For the hand design, the use of differential mechanisms simplifies the actuation scheme, as we utilize only two actuators for four fingers, achieving affordable dexterity. A design optimization framework assess the results of hand anthropometry studies to derive key parameters for the bio-inspired actuation design. The model assumptions are evaluated with the finite element method. The proposed finger has been fabricated with the Hybrid Deposition Manufacturing technique and the actuation mechanism's efficiency has been validated with experiments that include the computation of the finger workspace, the assessment of the force exertion capabilities, the demonstration of the feasible motions, and the grasping and manipulation capabilities. Also, the hand design is fabricated with off-the-shelf materials and rapid prototyping techniques while its efficiency has been validated using an extensive set of experimental paradigms that involved the execution of grasping and in-hand manipulation tasks with everyday objects.
Master of Science
This thesis presents the design, modeling, and development of adaptive robot hands that are capable of performing selective interdigitation, robust grasping, and dexterous, in-hand manipulation. The robotic fingers employ an adaptive actuation mechanism. The design is minimal and the hand is capable of performing selective interdigitation, robust grasping, and dexterous, in-hand manipulation. Particular emphasis has been given to the modeling and the analysis of the actuation mechanism. For the hand design, the use of differential mechanisms simplifies the actuation scheme, as we utilize only two actuators for four fingers, achieving affordable dexterity. A design optimization framework assess the results of hand anthropometry studies to derive key parameters for the actuation design. The robotic fingers and the anthropomorphic hand were fabricated using off-the-self materials and additive manufacturing techniques. Several experiments were performed to validate the efficacy of the robot hand.
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Nagai, Kiyoshi. „Studies on Grasping and Manipulation by Robotic Multifingered Hands and Arm-Hand Systems“. Kyoto University, 1995. http://hdl.handle.net/2433/160756.

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本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものである
Kyoto University (京都大学)
0048
新制・論文博士
博士(工学)
乙第8782号
論工博第2944号
新制||工||980(附属図書館)
UT51-95-B247
(主査)教授 吉川 恒夫, 教授 井上 紘一, 教授 島 進
学位規則第4条第2項該当
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Yates, Juliet Rose. „Hands-on modernism : representations of the hand in Dorothy Richardson's Pilgrimage and modernist literature 1914-1939“. Thesis, Keele University, 2012. http://eprints.keele.ac.uk/1186/.

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The fragmentation endemic to modernism poses the difficult question of how we read the modernist body. In this thesis, I propose a new critical approach in response to this question – theoretical partialism – whereby looking at the particular and reading the representation of the hand as a signifier offers further insight into wider concerns such as, female subjectivity, performativity, sexuality and societal positioning. Because the hand can be both male and female, it allows for an interpretation of the body which does not rely on biological determinism, masculine discourse or essentialist feminism but, instead, provides the site for a new understanding of the body and constructions of gendered identities. Theoretical partialism finds its origins in psychoanalysis, sexology and feminist discourse and suggests that the hand can be used as a starting point for a wider theoretical discussion of totality. The paradox of the hand’s power of unification and differentiation is explored and the fetishistic approach reveals that there is not necessarily one totality but the potential of understanding different interpretations of the total. Therefore, theoretical partialism is used not as a method of regaining conventional ideas of totality but rather as a means for gaining a reconstituted notion of the whole and of selfhood from the fragments of modernity. My thesis develops this approach through readings of six texts: predominantly Dorothy Richardson’s Pilgrimage; Arthur Munby’s material is also investigated in order to establish the hand’s significance in the Victorian imagination; and as a method of illustrating the extent to which the hand features as a signifier in modernism, I explore the fragmented form and gendered identities in James Joyce’s Ulysses, T. S. Eliot’s The Waste Land, Katherine Mansfield’s “The Little Governess” and Jean Rhys’s Voyage in the Dark.
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Sheikholeslami, Sara. „Data-driven design of expressive robot hands and hand gestures : applications for collaborative human-robot interaction“. Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/61300.

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Fast and reliable communication between human workers and robotic assistants (RAs) is essential for successful collaboration between these agents. This is especially true for typically noisy manufacturing environments that render verbal communication less effective. This thesis investigates the efficacy of nonverbal communication capabilities of robotic manipulators that have poseable, three-fingered end-effectors (hands). This work explores the extent to which different poses of a typical robotic gripper can effectively communicate instructional messages during human-robot collaboration. Within the context of a collaborative car door assembly task, a series of three studies were conducted. Study 1 empirically explored the type of hand configurations that humans use to nonverbally instruct another per- son (N=17). Based on the findings from Study 1, Study 2 examined how well human gestures with frequently used hand configurations were under- stood by recipients of the message (N=140). Finally, Study 3 implemented the most human-recognized human hand configurations on a 7-degree-of- freedom (DOF) robotic manipulator to investigate the efficacy of having human-inspired hand poses on a robotic hand compared to an unposed hand (N=100). Contributions of this work include the presentation of a set of hand configurations humans commonly use to instruct another person in a collaborative assembly scenario, as well as Recognition Rate and Recognition Confidence measures for the gestures that humans and robots expressed using different hand configurations. These experimental results indicate that most gestures are better recognized with a higher level of confidence when displayed with a posed robot hand. Guidelines and principles are provided based on these results for the mechanical design of robotic hands.
Applied Science, Faculty of
Mechanical Engineering, Department of
Graduate
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Rydberg, Nancy. „A discussion of the application of the Convention on the Rights of the Child to policies toward children and youth on the streets a case study of a municipal program in Buenos Aires, Argentina /“. CONNECT TO ELECTRONIC THESIS, 2007. http://dspace.wrlc.org/hand/1961/4123.

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Barzilay, Karen Northrup. „"To Go with an Ungloved Hand Was Impossible": A History of Gloves, Hands, Sex, Wealth, and Power“. W&M ScholarWorks, 1998. https://scholarworks.wm.edu/etd/1539626150.

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13

Georgiadis, Abraham. „VR Gaming - Hands On : The use and effects of bare hand gestures as an interaction method in multiplayer Virtual Reality Games“. Thesis, Linnéuniversitetet, Institutionen för medieteknik (ME), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-66863.

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The field of virtual reality (VR) is getting increasing attention from the scientific community and it is being portrayed by advertisements as the user interface (UI) of the future. This is a fair statement since the prior uses of VR that used to exist only in fiction movies and books are now widely available in many forms and settings to the public. One of the most interesting outcomes from this technological evolution is that now VR can be experienced through the use of a mobile phone and the addition of some inexpensive means typically in a form of a headset. The combination of the phone’s screen as attached to the headset creates a form of Head Mounted Display (HMD) which can be utilized in order for the user to be immersed within a virtual environment (VE). The argument here is that even if the means to get access to VR are cheap, this should not be the case with the experience as well. On the contrary, the low entry requirements in combination with a high quality experience are the basis for the medium's success and further adoption by the users. More specifically, the capability of utilizing a three dimensional space (3D) should not limit the medium’s use on just that but instead, this space should be used in order to offer immersive environments which make the user feel as if he is there.    There are many factors that contribute to that result and significant progress has been made to some such as the quality of screen or other hardware parts that allow the user get immersed into the virtual scenery, however, little progress has been made towards the conceptual means that allow the user of better experiencing this VE. Most of the VR applications so far are specifically designed for a single user session. This creates an isolation of the user from any other type of communities which further increases the stigma of VR being a solitary experience. Another issue is the interaction method that is available to users in order to interact with the VE. The use of buttons in most of the available headsets is a counter intuitive method for a person to interact with an environment that wants to be called real. The technological advancements in the field of image processing have resulted in many new methods of interaction and multimodal manipulation within VE and it would be worthy of exploring their effects on the user experience (UX) when used as an interaction method.    For these reasons, this thesis used the case of VR games as a setting to study how UX can be enhanced from its current state by introducing a bare hand gesture interaction method and expanding the VR setting in order to host two users in shared VE. Two individual studies were conducted where user feedback was collected in order to describe the effects of this approach in both a qualitative and quantitative manner. As results indicate, by utilizing gesture analysis on a headset equipped with a smartphone, it is possible to offer a natural and engaging solution for VR interaction capable of rich UXs while maintaining a low entry level for the end users. Finally, the addition of another player significantly affected the experience by influencing the emotional state of the participants in the game and further enforcing their feeling of presence within the VE.
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Cockayne, William R. „Two-hand, whole-hand interaction“. Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1998. http://handle.dtic.mil/100.2/ADA356098.

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Thesis (M.S. in Computer Science) Naval Postgraduate School, September 1998.
"September 1998." Thesis advisor(s): Michael Zyda, Rudy Darken. Includes bibliographical references (p. 43-48). Also available online.
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Ruppel, Emily (Emily C. ). „Hallowed hands“. Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/68472.

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Thesis (S.M. in Science Writing)--Massachusetts Institute of Technology, Dept. of Humanities, Graduate Program in Science Writing, 2011.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 31-37).
Human hand transplantation became a medical reality at the turn of the 2 1st century. Often hailed by media and the general public as miraculous, these life-changing surgeries are also highly controversial. Many doctors, ethicists, and medical professionals feel the benefits of having a hand transplant do not outweigh the risks of the immunosuppressive drugs required to keep the complex foreign tissues alive on the bodies of chronically disabled yet otherwise healthy people. Patients' reactions to having the operation, to the drugs, to the physical therapy, and to the psychological consequences of wearing the hand of a dead person range from grateful acceptance to disgust and requested reamputation. This thesis explores the struggles and triumphs of human hand transplants through the stories of several patients and doctors. The rise of hand transplantation as a field, including the ongoing controversy surrounding the first successful human hand transplant, is also related as insight into how doctors and patients in innovative medicine make decisions, and where hand transplantation stands as a technology to benefit both medicine and scientific research.
by Emily Ruppel.
S.M.in Science Writing
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Beeler, Isadora. „Tobacco hands“. Thesis, Boston University, 1994. https://hdl.handle.net/2144/37121.

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Thesis (M.A.)--Boston University
PLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
2031-01-01
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Hale-Hanes, Heidi A. „Hand In Hand Home Health Care“. Thesis, California State University, Long Beach, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10164122.

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The need for home health care is a growing need in the United States due to the shift of the “baby-boomers” into the post retirement years. However, there is a growing niche market within this aging population: the lesbian, gay, bisexual and transgendered (LGBT) elders who have lived their adult lives “out of the closet” and who are facing difficulty receiving care which is compassionate and culturally sensitive at the same time. The mission of Hand-In-Hand Home Health Care is to provide exceptional home health care with a team of professionals that provide patient-centered care which is culturally sensitive and compassionate, achieved with employee training developed by SAGE (Services & Advocacy for GLBT Elders). Hand-In-Hand Home Health Care will achieve economic viability within the first year through optimal cash flow management with Axxess client software and the initial capital assistance with a 7a Small Business Loan.

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Lindfors, Berger Ditte, und Emma Lundberg. „ART och skola - hand i hand?“ Thesis, Malmö högskola, Lärarutbildningen (LUT), 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-32899.

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Syftet med uppsatsen är att undersöka och få kunskap om elevers upplevelse av sin situation på en skola som bedriver ART- programmet och arbetar för integrering av ART i övrig undervisning och verksamhet.(ART - Aggression Replacement Training) Vi har även forskat i hur lärarna på den specifika skolan upplever situationen för eleverna i såväl skolgång som socialt samt hur lärarna arbetar med ART. Vi har använt oss av en kvalitativ undersökningsmetod där intervjuer med sammanlagt sju informanter ligger som grund för vårt forskningsresultat. Till vår kvalitativa undersökning kopplar vi bland annat teorin om fenomenologi, vilken utgår från en strävan att åsidosätta vår tidigare empiri och genom det få möjlighet att gripa tag i den subjektiva erfarenheten hos informanten. Vi vill också lyfta fram begreppet kontextualism, det vill säga att vi har en vilja att undersöka individer i det sammanhang de befinner sig i. Resultatet av intervjuerna med informanterna visar att lärarna anser att de ser en stor förändring hos elever som placeras på den specifika skola vi undersökt samt vilka genomgått eller genomgår ART: s program. De menar att efter genomgånget program visar eleverna prov på mognad och utveckling vilket resulterar i en positiv förändring i både skolarbetet samt i den sociala situationen. De ser en fördel med att ha ART integrerad i övrig verksamhet förutom de lektioner som är avsedda för programmet. Eleverna upplevde även de en förändring i sin livssituation sedan de börjat på den specifika skolan och deltagit i ART-programmet. De ansåg att ART hjälpt dem att hantera sin aggressivitet och givit dem verktyg för att kunna handla annorlunda. De uttryckte att det som skiljde deras förra skola från den nya är att de på den nya skolan får det stöd de behöver, till exempel genom ART:s metoder och strategier, samt att det finns fler pedagoger per elev och att klasserna är mindre. Följden av detta är att eleverna upplevde att deras koncentration ökade vilket resulterat i att skolgången blivit förbättrad. Slutsatsen av undersökningen är att ART integrerat i en skolverksamhet kan stödja aggressiva elever i att bryta sitt beteende. Vidare är slutsatsen att lärare och elever som ingår i en verksamhet med ART integrerad upplever skolsituationen som mer hållbar och positivt utvecklande än då eleverna ingick i en skolverksamhet utan ART eller där ART inte var integrerad i övrig verksamhet och i bemötande av eleverna.
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Santos, Elcio Alteris dos [UNESP]. „Dinamômetro biomédico para avaliação funcional das mãos“. Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/87061.

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Made available in DSpace on 2014-06-11T19:22:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-02-20Bitstream added on 2014-06-13T18:07:11Z : No. of bitstreams: 1 santos_ea_me_ilha.pdf: 1369014 bytes, checksum: 7ea566c05320b595e08fe89ae2170203 (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O teste de força de aperto das mãos tem como finalidade detectar eventuais patologias nos membros superiores e avaliar a força exercida pelas mãos de pacientes. Neste trabalho é descrito o desenvolvimento de um dinamômetro biomédico projetado para efetuar a avaliação funcional das mãos, através da utilização de moldes específicos. O equipamento é constituído basicamente por sensores com extensômetros metálicos, um circuito de condicionamento de sinais, um circuito de interfaceamento e por um display digital. O circuito de condicionamento de sinais foi implementado com um amplificador de instrumentação, um amplificador com ganho programável e por um filtro passa-baixas. O principal componente do circuito de interfaceamento é o microcontrolador ATMEGA8. O equipamento é robusto, apresenta resposta linear na faixa de 0 a 500 N, precisão de 0,54%, resolução de 0,70 N e histerese desprezível. O valor da força pode ser lida em um display e também na tela de um computador. Pode ser útil em Engenharia de Reabilitação, Fisioterapia e Terapia Ocupacional
In this work we describe the development of a biomedical dynamometer. It was designed with the goal of performing the functional evaluation of hands with specific shapes. The equipment is constituted by force sensors, a signal conditioning circuit, an interface circuit and a digital display. Metallic strain gages were used as sensors. The signal conditioning circuit is constituted by an instrumentation amplifier, a programmable gain amplifier and a low-pass filter. The main component of the interface circuit is an ATMEGA8 microcontroller. The instrument can measure forces with resolution of 0.70 N and precision of 0.54% in the range of 0 to 500 N. It is rugged, presents linear response and very small hysteresis. The value of the force can be read in a display and in a computer screen. The device can be useful in Rehabilitation Engineering, Physiotherapy and Ocupational Therapy
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Butler, Douglas. „Hands On Workshops“. Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-82428.

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Liedström, Jack. „Hands up-projektet“. Thesis, University of Skövde, School of Humanities and Informatics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-4102.

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Vance, Barbara R. „The Clasped Hands“. Ann Arbor, Mich. : ProQuest, 2006. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1430297.

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Thesis (M.A. in English)--S.M.U.
Title from PDF title page (viewed July 17, 2007). Source: Masters Abstracts International, Volume: 44-03, page: 1150. Adviser: Marshall Terry. Includes bibliographical references.
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Beitelschmidt, Michael, Anja Abdel-Haq, Paul Balzer, Christof Fetzer und Sabine Wieland. „Hands on MINT“. Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-138116.

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Technische und naturwissenschaftliche Studiengänge an Hochschulen - die sogenannten MINT-Fächer - bieten Absolventen und Absolventinnen gute Chancen für eine erfolgreiche Berufslaufbahn. In diesen anspruchsvollen Studiengängen einen Abschluss zu erhalten, ist jedoch nicht leicht: Vor Vor- und Zwischenprüfungen fallen oft mehr als 50 Prozent der Studienanfänger/-innen endgültig durch. Ziel der Hochschulen muss es daher sein, die Anzahl der Studienabbrecher/-innen zu reduzieren. Zwei mögliche Zielrichtungen für Maßnahmen sind somit die Motivation der Studierenden und die Vermittlung von Arbeits- und Lerntechniken.
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Escobar, Velásquez Karla, Silvera Mónica Yulissa Gutiérrez, Pinzón Luis Alberto Rosales und Carrera Irma Jeaniffer Meylin Valdivia. „Loncherita Free Hands“. Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/626062.

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El negocio presentado consiste en la elaboración de una lonchera desplegable con su complemento que son envases de material biodegradable, son productos que cumplen los estándares de calidad y contribuyen al medio ambiente, que brindan la facilidad de transportar los alimentos de un lugar a otro, sin llevar tantas cosas en las manos y puedan continuar con la rutina diaria con satisfacción. Estos productos serán mostrados a través de nuestra página web, radio y redes sociales. Toda esta gestión será supervisada por los perfiles de puestos idóneos para cada actividad dentro de la empresa, que fueron seleccionados a gran detalle para evitar falencias y/o incidentes a futuro en los procesos internos de la empresa. La inversión estimada para iniciar las operaciones en la empresa será S/ 444,814.38 soles, esto permitirá implementar la creación de la página Web y cubrir los gastos de marketing, iniciando de esta manera la elaboración y comercialización de los productos y con esto obtener una proyección de ventas favorable durante los 05 primeros años. Los emprendedores aportaran el 40% del capital, pero se necesitará de inversión externa para cubrir el otro 60%. Donde se le retribuirá al inversionista una rentabilidad de 13% anual y una participación del 2% de las ventas para el segundo año. El equipo de emprendedores está integrado por 4 futuros egresados de la Universidad Peruana de Ciencias aplicadas, todos con experiencia en diferentes campos empresariales sobre las cuales se apoya y recae este proyecto innovador y rentable que le facilitara la vida a muchas personas.
The presented business consists in the elaboration of a folding lunchbox with its complement that are containers of Eco-friendly material, they are products that meet quality standards and contribute to the environment, which provide the facility to transport food from one place to another, without carry so many things in your hands and can continue with the daily routine with satisfaction. These products will be shown through our website, radio and social networks. All this management will be supervised by the profiles of suitable positions for each activity within the company, which were selected in great detail to avoid failures and / or future incidents in the internal processes of the company. The estimated investment to start operations in the company will be S / 444,814.38 soles, this will allow the implementation of the website and cover the marketing expenses, thus initiating the preparation and marketing of the products and thus obtaining a projection of favorable sales during the first 5 years. Entrepreneurs will contribute 40% of the capital, but external investment will be needed to cover the other 60%. Where the investor will be rewarded with a 13% annual return and a 2% share of sales for the second year. The team of entrepreneurs is composed of 4 future graduates of the Universidad Peruana de Ciencias Aplicadas, all with experience in different business fields on which this innovative and profitable project is based and which will make life easier for many people.
Tesis
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Yaeger, Matthew. „Hands On Painting“. VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3823.

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How can we know something through how it is sensed? Making anthropomorphic, three-dimensional paintings through a set of basic, at-hand materials, I’m interested in how empathy, modesty, and doubt can mediate a tangible experience of an object. Challenging notions of perception, I want to create a heightened sense of awareness in which the intangible can be seen or felt.
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Jubran, Rachel, Hannah White, Alyson Chroust, Alison Heck und Ramesh S. Bhatt. „Experimental Evidence of Structural Representation of Hands in Early Infancy“. Digital Commons @ East Tennessee State University, 2018. https://dc.etsu.edu/etsu-works/2731.

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Hands convey important social information, such as an individual’s emotions, goals, and desires, are used to direct attention through pointing, and are a major organ for haptic perception. However, very little is known about infants’ representation of human hands. In Experiment 1, infants tested in a familiarization/novelty preference task discriminated between images of intact hands and images that contained first-order structure distortions (i.e., with locations of fingers altered to result in an unnatural configuration). In Experiment 2, infants tested in a spontaneous preference task exhibited a preference for scrambled hand images over intact images, indicating that 3.5-month-olds have gained sufficient sensitivity to the configural properties of hands to discriminate between intact versus scrambled images without any training in the laboratory. In both procedures, infants’ performance was disrupted by the inversion of images, suggesting that infants’ performance in upright conditions was not based on low-level features. These results indicate that sensitivity to the structure of hands develops early in life. This may lay the foundation for the development of the functional use of hand information for social communication.
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Strömberg, Trygve. „Vibration-induced neuropathy in the hand“. Lund : Dept. of Hand Surgery, Lund University, 1997. http://books.google.com/books?id=8hxsAAAAMAAJ.

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Lind, Marie-Louise. „Hairdressers - hand eczema, hair dyes and hand protection /“. Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-900-9/.

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Ng, Yee-ting Omi. „Handwashing practice in Hong Kong during SARS (2003) and bird flu (2004)“. Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B43958588.

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Guttmann, Oliver. „Hand eczema“. Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-88559.

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Lee, Geoffrey R. „In hand“. Connect to this title online, 2008. http://etd.lib.clemson.edu/documents/1211389315/.

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Guttmann, Oliver Philipp. „Hand eczema“. kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8855/.

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Rathi, Ritesh. „Hand gestures“. Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/28158.

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Arrué, Collahua Melanie Amy Elizabeth, Tejada Karen Antuane Cespedes, Cuba Carlos Alberto Rodriguez und Hidalgo Carlos Enrique Rodriguez. „Hand roll“. Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/656654.

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El presente trabajo es realizado por alumnos de la Universidad Peruana de Ciencias Aplicadas, la idea de negocio se elaboró con el fin de ayudar en la alimentación de las personas y la practicidad o poco tiempo de los consumidores. Nuestro principal objetivo es la creación, distribución y comercialización de hand rolls de pollo furai y un Hand Roll de verduras y de regalo se dará a un vaso de chicha completamente gratis. Se identificó que el principal problema es la falta de tiempo en la elaboración de alimentos, snacks saludables, alimentos en la media mañana o media tarde, por lo que se busca ayudar a estas personas a que ahorren tiempo y sean más prácticos; por lo que se creó un pack de Hand Roll listos para disfrutar. Yan Ken Roll surge de la sinergia de las palabras “Yan ken Po”, siendo un nombre original y único, sobre todo una marca peruana. Este pack de Hand Roll tendrá los ingredientes básicos son el pollo, el arroz y las verduras. Será distribuida de forma únicamente por delivery, principalmente al distrito de San Miguel y aledaños. Finalmente, determinamos que nuestro hand roll está orientada al público en general, sin embargo, nuestro público objetivo está representado por personas quienes buscan algo rápido al paso y nutritivo, que les permita mantener un estilo de vida saludable y a la vez poder satisfacer su alimentación. Nuestro propósito es que YAN KEN ROLL transcienda y se sitúe en el top of mind del consumidor.
This work is carried out by students of the Peruvian University of Applied Sciences, the business idea was developed in order to help feed people and the practicality or short time of consumers. Our main objective is the creation, distribution and commercialization of furai chicken hand rolls and a vegetable hand roll and as a gift it will be given to a glass of chichi completely free. It was identified that the main problem is the lack of time in the preparation of food, healthy snacks, food in the mid-morning or mid-afternoon, so it seeks to help these people to save time and be more practical; reason why a pack of Hand Roll ready to enjoy was created. Yan Ken Roll arises from the synergy of the words "Yan ken Po", being an original and unique name, especially a Peruvian brand. This pack of Hand Roll will have the basic ingredients are chicken, rice and vegetables. It will be distributed solely by delivery, mainly to the San Miguel district and surrounding areas. Finally, we determine that our hand roll is oriented to the general public, however, our target audience is represented by people who are looking for something fast-paced and nutritious, which allows them to maintain a healthy lifestyle and at the same time be able to satisfy their diet. Our purpose is for YAN KEN ROLL to transcend and be in the top of mind of the consumer.
Trabajo de investigación
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Nilsson, Anna, und Cathrine Wallmark. „Helping Hand“. Thesis, Malmö högskola, Lärarutbildningen (LUT), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-30447.

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Vi har i denna uppsats diskuterat och belyst hur den optimala vägledningen skulle kunna se ut. Anledningen till detta är att vi planerar att starta ett eget företag inom vägledning och vi har genom detta examensarbete lagt grunden till en affärsidé kring hur vårt företag i framtiden kan arbeta med studie- och yrkesvägledning. Detta har vi gjort genom intervjuer med studie- och yrkesvägledare på Infoteket och Malmö högskola samt intervjuer med sökande som varit och besökt dessa verksamheter. Vi har kommit fram till att varken Malmö högskola eller Infoteket bedriver det som vi efter denna uppsats anser vara den optimala vägledningen. Verksamheterna har inte någon möjlighet att individanpassa vägledningen på ett sådant sätt att vi kallar det optimalt, de väljer ibland att inte klargöra ramar och samtalsinnehåll för de sökande dessutom känner de sökande ibland att de inte satt igång någon process överhuvudtaget när de gått därifrån. Utifrån detta arbete har vi insett att det krävs en hel del för att kunna erbjuda den optimala vägledningen. Det allra viktigaste, och kanske svåraste, som vi kommit fram till är att vägledningen alltid måste individanpassas. Det som är optimal vägledning för en sökande är inte den optimala för en annan. För att kunna individanpassa samtalen har vi kommit fram till att det krävs flexibilitet, resurser m.m. Detta för att kunna skapa ett forum där det finns möjlighet att anpassa miljön, samtalsklimatet och vägledningsprocessen till varje individ. Vi vill dock tillägga att det viktigaste av allt är att den optimala vägledningen ska utgå ifrån att den sökande känner sig nöjd och fått den hjälp som han eller hon var ute efter.
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Nilsson, Alexandra, und Peter Hamlén. „Från second hand till first hand : -En undersökning av konsumentens inställning till second hand kläder“. Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-176665.

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Syftet med studien var att undersöka hur klädesaffärer kan skapa en mer positiv syn på second hand kläder bland konsumenter. Undersökningen utfördes genom att använda Tricomponent Attitude modellen och erkända strategier för attitydförändring. Tricomponent Attitude modellen utgörs av den kognitiva, affektiva samt konativa delen medan attitydstrategierna utgörs av tillvägagångssätt för att förändra attityden. En kvantitativ enkätundersökning utfördes och sändes ut till respondenterna med hjälp utav sociala nätverk och forum. Totalt samlades 343 svar in. Det visade sig att konsumentens inställning till second hand kläder mestadels utgjordes av den kognitiva delen av Tricomponent Attitude modellen, men att det samtidigt existerade ett klart samspel mellan modellens tre delar. Dock fick alla strategier till attitydförändring svaga resultat och skulle på så vis inte påverka konsumenterna att köpa mer second hand kläder. Den huvudsakliga upptäckten var att klädesaffärerna inte har en tillräckligt stark position för att påverka konsumenternas inställning till second hand kläder men att konsumentens positiva uppfattning om second hand kläder visar att förutsättningarna för en ökad konsumtion finns.
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Vollenbruch, Ulrich. „Design of reconfigurable digital phase locked loops for multi-standard, multi-band mobile radio terminals“. München Verl. Dr. Hut, 2008. http://d-nb.info/992163412/04.

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Mnyusiwalla, Hussein. „Qualité de prise dans le contexte de la planification de mouvements de préhension et de manipulation dextre en robotique“. Thesis, Poitiers, 2016. http://www.theses.fr/2016POIT2271/document.

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Le travail présenté s'intéresse à la problématique générale de la mise en oeuvre de mains robotiques à haut niveau de dextérité. Dans ce contexte, nous nous intéressons à la synthèse de prise d'objets en prenant en compte les contraintes propres à la tâche de manipulation visée. La manière dont l'objet est saisi a une importance capitale sur le bon déroulement d'une tâche.Le développement d'algorithmes capables de générer automatiquement des prises optimales implique avant tout la nécessité de définir la notion de prise optimale au regard de la tâche cible. Pour répondre à ce problème, la communauté scientifique propose dans la littérature de nombreux critères de qualité et continue à en développer de nouveaux. Dans cette thèse, nous présentons une extension des travaux proposés avec une étude approfondie de ces critères dans le cadre de la manipulation dextre. Ces critères sont évalués avec une main robotique entièrement actionnée à quatre doigts et seize articulations.Nous quantifions l'efficacité de ces critères dans le cadre de la réalisation de tâches de manipulation fine avec trois types d'objets spécifiques. Deux groupes de critères sont étudiés : d'une part des critères s'appuyant uniquement sur la position des points de contact, et, d'autre part, des critères prenant en compte la cinématique du préhenseur. Cette étude nous a permis de sélectionner un ensemble de critères pertinents pour résoudre le problème de synthèse de prise que nous avons mis en oeuvre dans un processus basé sur une approche évolutionnaire. Cette approche a été validée dans l'environnement de simulation OpenRAVE, puis expérimentalement avec la nouvelle main RoBioSS
The work presented in this thesis concerns object grasping with dexterous robotic hands. In this work, we are going to focus on the grasp synthesis problem by taking into account the in-hand manipulation task. The initial grasp has a capital role for the successful completion of a given task.In order to develop algorithms which are able to generate automatically correct grasps for a manipulation task, we need to define suitable grasp quality metrics to assess the validity of a grasp. Throughout the years, a large variety of quality measures have been proposed in the literature and researchers keep on developing new ones. However those quality measures are generally developed for simple grippers and for grasping tasks. In this thesis, we will extend the study of selected interesting grasp quality measures for in-hand manipulation tasks. These quality measures will be evaluated on a four finger robotic hand with sixteen fully actuated degrees of freedom.We will assess the chosen quality measures for in-hand manipulation tasks with three different carefully selected type of objects. The quality metrics are classified in two groups, first one focuses exclusively on the location of contact points and the second one considers the kinematics of the robotic hand. The review of these quality measures led us to select the ones meaningful for solving the grasp synthesis problem for in-hand manipulation. The grasping pipeline implemented to generate the correct grasps is based on an evolutionary approach using a mix of the selected quality measures. The proposed approach was tested in the OpenRAVE robotic simulator and also validated experimentally with the new RoBioSS hand
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Anani, Sani. „Hand Reader – A hand Geometry Based Personal Verification System“. Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-58124.

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This report presents my bachelor thesis performed at the Department of Applied Physics and Electronics at UmeåUniversity. The Digital Media Lab was the assigner, supervising and assisting me during the project.   A simple and smart system to verify a person’s identity using hand geometry as a biometrical identity is developed. The system should tolerate some deviation in hand placement and will not use pins or pegs. A complete system, hardware and software, is delivered. A webcam based hand-scanner is constructed and designed to operate on a PC utilizing Matlab for image processing.
Denna rapport beskriver mitt examensarbete utfört vid institutionen för Tillämpad Fysik och Elektronik vid Umeå Universitet. Uppdragsgivare var Digital Media Lab som har stöttat och assisterat mig under hela projektet.   Målet med projektet var att utveckla ett system som ska verifiera en persons identitet genom att använda handens geometri som en biometrisk identitet. Systemet skall tolerera några avvikelser i handplaceringar och kommer inte att använda stift eller pinnar. Systemet består även av olika bildbehandlingsmetoder programmerade i Matlab. Systemet är byggt för att fungera på en PC.
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Jaroň, Lukáš. „Ovládání počítače gesty“. Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2012. http://www.nusl.cz/ntk/nusl-236609.

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This masters thesis describes possibilities and principles of gesture-based computer interface. The work describes general approaches for gesture control.  It also deals with implementation of the selected detection method of the hands and fingers using depth maps loaded form Kinect sensor. The implementation also deals with gesture recognition using hidden Markov models. For demonstration purposes there is also described implementation of a simple photo viewer that uses developed gesture-based computer interface. The work also focuses on quality testing and accuracy evaluation for selected gesture recognizer.
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Wagner, Thomas R. „Hands-on functional education“. Menomonie, WI : University of Wisconsin--Stout, 2005. http://www.uwstout.edu/lib/thesis/2005/2005wagnert.pdf.

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Sharp, L. Kathryn, und Hongxia Zhao. „Hands-on Science Investigations“. Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/4258.

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Smith, John Warner. „A Mandala of Hands“. ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1484.

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Pharr, Saiward H. „Hands's own Tamar: sources, coding, and psychology /“. Auburn, Ala., 2006. http://repo.lib.auburn.edu/2006%20Spring/master's/PHARR_SAIWARD_21.pdf.

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Hellwig, Katharina. „Handykompetenz in der Grundschule : theoretische Konzeptualisierung und empirische Prüfung eines Testinventars /“. Göttingen : Cuvillier, 2009. http://d-nb.info/994852436/04.

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Kärkkäinen, Heli. „Hand i hand? : Möten mellan kvinnor i 1890-talets Stockholm“. Thesis, Södertörns högskola, Institutionen för kultur och kommunikation, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-9429.

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Syftet med uppsatsen är att undersöka vilka hinder som fanns att få till stånd jämlika möten över- och underklassen under det sena 1800-talet i Stockholm. Ett ytterligare syfte är att granska hur den borgerliga kvinnan respektive arbetarkvinnan konstruerades av sig själv och av varandra. Materialet som granskas är anteckningar från Samkväm för kvinnor ur olika yrkesgrupper och protokoll från Stockholms Allmänna Kvinnoklubb.Metoden som används är hermeneutisk och teorierna som används är den där Simone de Beauvoir beskriver hur den andra konstrueras, samt Karin Johannissons slutsatser om hur arbetarkvinnan närmast ansågs som en annan ras under det sena 1800-talet.Undersökningen visar att det fanns en uppriktig vilja bland de borgerliga kvinnorna att mötas på jämlika villkor. Men de ekonomiska skillnaderna skapade hinder för det, liksom tidens föreställningar om arbeterskan.Hur den borgerliga kvinnan konstrueras av arbeterskorna framträder inte tillräckligt tydligt för att kunna dra några generella slutsatser av, medan hon av ”de sina” betraktas som det självklara subjektet. Arbetarkvinnan ser sig som ett subjekt i Kvinnoklubben, medan hon ser sig som ett objekt i den omgivande världen. För de borgerliga kvinnorna blir hon det objekt genom vilket de själva konstruerar sig som subjektet.
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Sporrong, Psarakis Konstantinos K., Sara Nikkhakian und Camilla Johnsson. „Second Hand i Första Hand : En undersökning om second handklädesmarknaden“. Thesis, Stockholm University, School of Business, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-5960.

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Vi har valt att undersöka second handklädesmarknaden. På senare tid har intresset för andra handskläder ökat markant. Det finns två huvudsakliga aktörer på marknaden. De består av biståndsorganisationer som syftar till välgörande ändamål, samt de second handbutiker som har som mål att bevara gamla moden. I och med en ökad efterfrågan har marknaden utvecklats rejält. Från att ha burit en stämpel av fattigdom och skam har second handklädesmarknaden blivit ett mer naturligt val för många individer. Kundgruppen har utökats till att inte enbart inbegripa fattiga människor, utan även människor med intresse för mode. Denna kraftiga tillväxt har resulterat i en prisökning, varför vår undersökningsfråga ska besvara varför priset på second handkläder har ökat. Som syfte ämnade vi att först och främst ge en beskrivande bild av priset second handklädesmarknaden i förhållande till nyproduktionsmarknaden. Detta gjordes genom en kvantitativ studie, i form av en prisjämförelse. För att ge en mer förklarande bild till varför det ser ut som det gör genomfördes en intervju, som kvalitativ undersökning. För att finna svar på vår fråga har vi tagit hjälp av teorier om köpbeteende och priskänslighet. I analysen kopplade vi sedan samman dessa teorier med resultat från empirin.

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To, James Jiann Hua. „Hand-in-Hand, Heart-to-Heart:Qiaowu and the Overseas Chinese“. Thesis, University of Canterbury. Social and Political Sciences, 2009. http://hdl.handle.net/10092/4288.

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Following the violent crackdown on students demonstrating in Tiananmen Square in June 1989, tens of thousands of sympathetic ethnic Chinese and nationals of the People’s Republic of China (PRC) from across the globe (hereafter described as the Overseas Chinese or OC1) unified in protest against the Chinese Communist Party (CCP). While some were too afraid to speak out, others were much more critical and antagonistic by calling for democratic reform on the mainland.2 Fearing an escalation of anti-CCP sentiment amongst a diaspora crucial to its national interests, Beijing promptly intensified qiaowu gongzuo (hereafter described as qiaowu or OC work) to deal with the precarious situation. It employed a foreign legion of diplomats, attaches from various government ministries and specialist qiaowu cadres to aggressively manage and control strategic OC communities under a comprehensive set of influential tools and persuasive techniques.3 Over the next two decades, the CCP continually developed and improved qiaowu to the extent that it had become more successful with these methods in the current period than any other era – particularly so with new migrants and PRC students. Such prowess became apparent in 2008, when large numbers of the OC again took to the streets in heated protest. This time their response was not in defiance of the regime, but in strong support of China and its leaders. How has qiaowu been able to influence and manage the OC in this way? Why have qiaowu efforts worked with such success? Why has the CPP become so confident in advancing OC work since the crisis of 1989? This thesis explains the nature and development of qiaowu, details its specific work methods, and analyzes the platforms employed to advance relations with the OC diaspora. By assessing a wide range of Chinese language references, primary source policy documents and internal memoranda, this thesis argues that over decades of counter-efforts from rival political factions, gradual cultural assimilation, changes in OC demographics, technology and the international geo-political climate, qiaowu has served as an accomplished and necessary component of the CCP’s modernized propaganda and thought work system for influencing, managing and unifying a heterogeneous population of OC for Beijing’s national interests.
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Au, Kin-hei Timothy, und 區建熙. „Quantitative assessment of hand function by hand motion analysis usingcyberglove“. Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B47849988.

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Hand motion analysis methods have been providing researchers with motion investigation initiatives, revealing motion features and mechanisms in both healthy subjects and patients suffering from hand dysfunctions. Technical advancements have led to the maturation of motion capturing methods such as goniometric gloves. In this project, the CyberGlove as a manufactured product was chosen as a potential tool for the development of a hand function assessment system that would ultimately distinguish between healthy subjects and patients suffering from hand dysfunctions. In this study, the evaluation of the CyberGlove as a feasible clinical tool and its technical adaptations were done in parallel. The sensor output characteristics were investigated using X-ray photography as a spatial golden standard and the sensors were shown to exhibit linear qualities with optimal nonlinearities at 0.6%. The measurement sensitivity and accuracy by the CyberGlove was improved by establishing a calibration protocol suiting the sensor characteristics. Through a calibration protocol using calibration tools made by thermoplastics, the angular measurement error was found to decrease from 7.2% to 1.2%. The technical development of the software part of the project involved the inclusion of data preprocessing, display and analysis modules. To investigate the motion exhibited by healthy subjects, 32 healthy subjects were recruited and they were asked to complete a series of motion according to a designed motion protocol involving a static trial, a timed-grip trial and a rapid-grip trial. Motion features were extracted from recorded motion data by identification and quantification of temporal or spatial characteristics in motion such as joint sequence of events, angular kinematics, finger tip path features and phase diagram features. Some features were evaluated by pattern correlation analysis by linear regression, and healthy subjects all shared similar patterns resulting in high levels of regression coefficients R2 and low levels of slope deviations m. The establishment of motion features along with a prototype motion measurement system allows the continuous development on the CyberGlove as a hand function assessment tool when supported by later clinical adaptations or studies.
published_or_final_version
Orthopaedics and Traumatology
Master
Master of Philosophy
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Otto-de, Haart E. Grace. „Hand movements and the hemispheres : asymmetries in hand and hemispace“. Thesis, University of Aberdeen, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.424986.

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This thesis presents a series of experimental investigations into left and right hand performance in right-handed participants.  The experiments were designed to identify differences in movement kinematics when task characteristics varied in aiming and prehension movements, particularly along dimensions that were thought to differ between the hemispheres. The first part of the thesis reviews the existing literature on the relevant topics of motor control.  There is extensive evidence to argue for distinct but complementary contributions from each hemisphere in the control of movements, with the emphasis on the left hemisphere, which plays a significant role in the organization of movements on both sides of the body.  There is also support for the claim that the right hemisphere has a specialised role in visually-guided movements when visuo-spatial processing is involved in the form of localizing target positions.  Furthermore, performance differences are investigated with respect to hemisphere. The second part of the dissertation presents a series of investigations of neurologically intact participants.  In Experiment 1 and 2, 22 participants were required to make pointing movements with the index finger across the hemisphere in visual and non-visual conditions.  The main finding of this study was ipsilateral movement advantages for both hands.  Contrary to previous claims, these ipsilateral advantages, even when no vision was available, were the consequences of biomechanical factors rather than within-hemispheric processing.  A right hand advantage was found for movement duration.  In Experiment 3, 22 participants were required to point to suddenly-appearing targets aligned along the horizontal midline. The focus of this study was on right hemisphere participation in a pointing task in which the visuo-spatial demands were manipulated in the form of target location uncertainty.  Contrary to previous claims, no evidence was found for the attenuation of right hand performance or even the facilitation of left hand performance.  The dominant hand was noticeably more accurate and took less time decelerating.  Main findings of this study were ipsilateral movement advantages for both hands.  In Experiment 4, 20 participants were required to grasp and pick up target blocks of differing length and width to examine whether increased precision would exacerbate a previously reported hand difference on a grip aperture timing measure.  The left hand reached maximum grip aperture earlier than the right hand but, contrary to expectations, this hand difference was not influenced by the manipulation of precision demands.  Hemispatial effects were found for transport and grip related dependent measures.  In the final Experiment 5, the area of hand performance differences was explored while both hands were grasping targets simultaneously by requiring 14 participants to grasp and pick up objects of the same or different lengths.  The manipulation of hemispace resulted in a common movement duration of the limbs.  An overall larger grip aperture was found for the left hand but was not affected by the task requirement of the right hand such that grip apertures of the hands were independently scaled.
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