Thematische Bibliographien / Gshare

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Auswahl der wissenschaftlichen Literatur zum Thema „Gshare“

Autor: Grafiati

Veröffentlicht am 28. Juni 2021

Zuletzt aktualisiert am 17. Februar 2022

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Zeitschriftenartikel zum Thema "Gshare"

Tarjan, David, und Kevin Skadron. „Merging path and gshare indexing in perceptron branch prediction“. ACM Transactions on Architecture and Code Optimization 2, Nr. 3 (September 2005): 280–300. http://dx.doi.org/10.1145/1089008.1089011.

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Ma, Wenheng, Qiao Cheng, Yudi Gao, Lan Xu und Ningmei Yu. „An Ultra-Low-Power Embedded Processor with Variable Micro-Architecture“. Micromachines 12, Nr. 3 (10.03.2021): 292. http://dx.doi.org/10.3390/mi12030292.

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Embedded processors are widely used in various systems working on different tasks with different workloads. A more complex micro-architecture leads to better peak performance and worse power consumption. Shutting down the units designed for performance enhancement could improve energy efficiency in low-workload scenarios. In this paper, we evaluated the energy distribution in various embedded processors. According to the analysis, pipeline registers and the dynamic branch predictor, which are employed for better peak performance, have great impacts on energy efficiency. Thus, we proposed an ultra-low-power processor with variable micro-architecture. The processor is based on a 4-stage pipeline core with a Gshare branch predictor, and all units work in high-performance mode. In normal mode, the Gshare predictor is shut down and Always-Not-Taken prediction is used. In low-power mode, some of the pipeline registers are bypassed to avoid unnecessary energy dissipation and improve executing efficiency. A mode register (MR) is designed to indicate current working mode. Switching between different modes is controlled by the software. The proposed core is implemented in 40 nm technology and simulated with the traces of 17 benchmarks in Embench. The average amounts of power consumed by the respective modes are 41.7 μW, 59.7 μW and 71.1 μW. The results show that normal mode (N-mode) and low-power mode (L-mode) consume 16.08% and 41.37% less power than high-performance mode (H-mode) on average. In best case scenarios, they could save 25.36% and 49.30% more power than H-mode. Considering the execution efficiency evaluated by instructions per cycle (IPC), the proposed processor consumes 7.78% or 51.57% less energy for each instruction than the baseline core. The area of the proposed processor is only 7.19% larger than the baseline core, and only 3.08% more power is consumed in H-mode.

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Rhodes, Christophe, und Robert Strandh. „Gsharp, un éditeur de partitions de musique interactif et personnalisable“. Document numérique 11, Nr. 3-4 (30.12.2008): 9–28. http://dx.doi.org/10.3166/dn.11.3-4.9-28.

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Balestri, Francesco, Vito Barracco, Giovanni Renzone, Tiziano Tuccinardi, Christian Silvio Pomelli, Mario Cappiello, Marco Lessi et al. „Stereoselectivity of Aldose Reductase in the Reduction of Glutathionyl-Hydroxynonanal Adduct“. Antioxidants 8, Nr. 10 (22.10.2019): 502. http://dx.doi.org/10.3390/antiox8100502.

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The formation of the adduct between the lipid peroxidation product 4-hydroxy-2-nonenal (HNE) and glutathione, which leads to the generation of 3-glutathionyl-4-hydroxynonane (GSHNE), is one of the main routes of HNE detoxification. The aldo-keto reductase AKR1B1 is involved in the reduction of the aldehydic group of both HNE and GSHNE. In the present study, the effect of chirality on the recognition by aldose reductase of HNE and GSHNE was evaluated. AKR1B1 discriminates very modestly between the two possible enantiomers of HNE as substrates. Conversely, a combined kinetic analysis of the glutathionyl adducts obtained starting from either 4R- or 4S-HNE and mass spectrometry analysis of GSHNE products obtained from racemic HNE revealed that AKR1B1 possesses a marked preference toward the 3S,4R-GSHNE diastereoisomer. Density functional theory and molecular modeling studies revealed that this diastereoisomer, besides having a higher tendency to be in an open aldehydic form (the one recognized by AKR1B1) in solution than other GSHNE diastereoisomers, is further stabilized in its open form by a specific interaction with the enzyme active site. The relevance of this stereospecificity to the final metabolic fate of GSHNE is discussed.

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Ruan, Wenly, Melinda Engevik, Alexandra Chang-Graham, Joseph Hyser und James Versalovic. „7 LACTOBACILLUS REUTERI SUPPRESSES PRO-INFLAMMATORY DRIVEN REACTIVE OXYGEN SPECIES IN VITRO IN HUMAN INTESTINAL EPITHELIAL CELLS AND IN VIVO IN A TNBS COLITIS MOUSE MODEL“. Inflammatory Bowel Diseases 26, Supplement_1 (Januar 2020): S41. http://dx.doi.org/10.1093/ibd/zaa010.106.

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Abstract Background Reactive oxygen species (ROS) play a role in maintaining intestinal epithelial homeostasis and are normally kept at low levels via antioxidant compounds. Dysregulation of ROS can lead to intestinal inflammation and contribute to inflammatory bowel disease (IBD). Select gut microbes possess the enzymatic machinery to produce antioxidants whereas others can dysregulate levels of ROS. Our model microbe, Lactobacillus reuteri (ATCC PTA 6475), has been demonstrated to reduce intestinal inflammation in mice models. It contains the genes encoding two distinct GshA-like glutamylcysteine ligases. We hypothesize that L. reuteri can secrete γ-glutamylcysteine to suppress ROS, minimize NFκB activation and regulate secretion of e pithelial cytokines. Methods & Results Conditioned media from L. reuteri was analyzed via mass spectrometry to confirm the presence of γ-glutamylcysteine. All cysteine containing products including γ-glutamylcysteine were fluorescently tagged in the conditioned media and then incubated with HT29 cell monolayers as well as human jejunal enteroid (HJE) monolayers. γ-glutamylcysteine was demonstrated to enter intestinal epithelial cells based on microscopy. Next, a Thioltracker assay was used to show increased intracellular glutathione levels by L. reuteri secreted γ-glutamylcysteine. HT29 cells and HJEs were then treated with IL-1β or hydrogen peroxide, and L. reuteri metabolites as well as γ-glutamylcysteine significantly suppressed pro-inflammatory cytokine driven ROS and IL-8 production. L. reuteri secreted products also reduced activity of NFκB as determined by a luciferase reporter assay. γ-glutamylcysteine deficient mutants were generated by targeted mutagenesis of GshA genes, and these mutant L. reuteri strains had a diminished ability to suppress IL-8 production and ROS. To further test the role of L. reuteri secreted γ-glutamylcysteine in vivo, a 2,4,6-Trinitrobenzenesulfonic acid (TNBS)- induced mouse colitis model was used. Adolescent mice were orogavaged with PBS, L. reuteri, L. reuteri GshA2 mutant, or γ-glutamylcysteine for a week after which TNBS was rectally administered to induce colitis. We demonstrate that L. reuteri and γ-glutamylcysteine can suppress histologic inflammation compared to PBS control and L. reuteri GshA2 mutant groups. Conclusions Together these data indicate that L. reuteri secretes γ-glutamylcysteine which can enter the intestinal epithelial cells and modulate epithelial cytokine production. It acts via suppression of ROS and NFκB which then decreases IL-8 production. We are able to demonstrate this in vitro in both HT 29 cells and HJEs. We now also demonstrate this in vivo in a mouse colitis model. These experiments highlight a prominent role for ROS intermediates in microbiome-mammalian cell signaling processes involved in immune responses and intestinal inflammation.

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Shedlock, K. M., D. Giardini, G. Grunthal und P. Zhang. „The GSHAP Global Seismic Hazard Map“. Seismological Research Letters 71, Nr. 6 (01.11.2000): 679–86. http://dx.doi.org/10.1785/gssrl.71.6.679.

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Martinez-cengotitabengoa, M., C. Bermudez-ampudia, M. P. Lopez, A. Garcia-alocen, I. Gonzalez-ortega, I. Zorrilla und A. Gonzalez-pinto. „First bipolar episode and functionality: Relation with depressive symptoms and inflammation levels“. European Psychiatry 33, S1 (März 2016): S122—S123. http://dx.doi.org/10.1016/j.eurpsy.2016.01.154.

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IntroductionIt is important to make an early and effective intervention from the first bipolar episode. The presence of depressive symptoms in the course of a manic episode could influence negatively the evolution and the prognosis of the patient. Inflammation and oxidative stress are also related with functionality.ObjectivesTo explore the relationship between depressive symptoms during a first episode of mania, inflammatory parameters and patient functionality during the follow-up.MethodWe included in the study 92 are patients with a first manic episode and 92 matched healthy controls. We compared 13 inflammatory/oxidative stress parameters measured at baseline (TFNα, IL6, PGE2, MCP1, TBARS, NO2, SOD, CAT, GSHTOT, GSSG, GSHfree, GPx, TAS) between both groups. Between patients, 46 presented pure mania (PM) (no depressive symptoms) and 46 mixed mania (MM) (with depressive symptoms). We explored the influence of inflammatory factors in functionality, exploring differences between PM and MM. To measure patients’ general functioning one year after illness onset, we used the Functional Assessment Short Test (FAST).ResultsWe found significant differences in TFNα, MCP1 and TBARS (higher in patients) and in SOD, GSHtot, GSSG, GSHfree, GPx and TAS levels (lower in patients). Only In MM group, there was a significant influence of SOD and GSHfree in FAST scores suggesting that a higher antioxidant levels at baseline the patient functionality improves one year after.ConclusionsSome parameters of oxidative stress at baseline are related with patient's functionality one year after the first episode of mania, but only when mania debuts with depressive symptons simultaneously.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Giardini, D., P. Basham und M. Bery. „THE GLOBAL SEISMIC HAZARD ASSESSMENT PROGRAM (GSHAP)“. Terra Nova 4, Nr. 6 (November 1992): 623–27. http://dx.doi.org/10.1111/j.1365-3121.1992.tb00609.x.

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Jänsch, André, Maher Korakli, Rudi F. Vogel und Michael G. Gänzle. „Glutathione Reductase from Lactobacillus sanfranciscensis DSM20451T: Contribution to Oxygen Tolerance and Thiol Exchange Reactions in Wheat Sourdoughs“. Applied and Environmental Microbiology 73, Nr. 14 (11.05.2007): 4469–76. http://dx.doi.org/10.1128/aem.02322-06.

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ABSTRACT The effect of the glutathione reductase (GshR) activity of Lactobacillus sanfranciscensis DSM20451T on the thiol levels in fermented sourdoughs was determined, and the oxygen tolerance of the strain was also determined. The gshR gene coding for a putative GshR was sequenced and inactivated by single-crossover integration to yield strain L. sanfranciscensis DSM20451TΔgshR. The gene disruption was verified by sequencing the truncated gshR and surrounding regions on the chromosome. The gshR activity of L. sanfranciscensis DSM20451TΔgshR was strongly reduced compared to that of the wild-type strain, demonstrating that gshR indeed encodes an active GshR enzyme. The thiol levels in wheat doughs fermented with L. sanfranciscensis DSM20451 increased from 9 μM to 10.5 μM sulfhydryl/g of dough during a 24-h sourdough fermentation, but in sourdoughs fermented with L. sanfranciscensis DSM20451TΔgshR and in chemically acidified doughs, the thiol levels decreased to 6.5 to 6.8 μM sulfhydryl/g of dough. Remarkably, the GshR-negative strains Lactobacillus pontis LTH2587 and Lactobacillus reuteri BR11 exerted effects on thiol levels in dough comparable to those of L. sanfranciscensis. In addition to the effect on thiol levels in sourdough, the loss of GshR activity in L. sanfranciscensis DSM20451TΔgshR resulted in a loss of oxygen tolerance. The gshR mutant strain exhibited a strongly decreased aerobic growth rate on modified MRS medium compared to either the growth rate under anaerobic conditions or that of the wild-type strain, and aerobic growth was restored by the addition of cysteine. Moreover, the gshR mutant strain was more sensitive to the superoxide-generating agent paraquat.

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Clay, Sharon A., und William C. Koskinen. „Adsorption and Desorption of Atrazine, Hydroxyatrazine, andS-Glutathione Atrazine on Two Soils“. Weed Science 38, Nr. 3 (Mai 1990): 262–66. http://dx.doi.org/10.1017/s0043174500056502.

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Adsorption and desorption isotherms for atrazine and two metabolites, hydroxyatrazine (HA) andS-glutathione atrazine (GSHA), were determined by batch equilibration on Plano and Waukegan silt loam soils at two soil pH levels (Plano, 6.1 and 4.5; Waukegan, 6.1 and 4.0). Freundlich adsorption isotherms were not affected by soil type except for GSHA at pH 4.0 to 4.5. When averaged over both soils, the order of adsorption at pH 6.1 was atrazine (Kf= 3.7) < GSHA (Kf= 7.3) << HA (Kf= 25) and at pH 4.0–4.5 was atrazine (Kf= 6.1) << HA (Kf= 58) ≤ GSHA (Kf: Plano = 35; Waukegan = 78). The average slope of the adsorption isotherms (1/nads) was 0.81. The slopes of all desorption isotherms (1/ndes) were less than their respective 1/nads, indicating hysteresis. Atrazine desorbed into soil solution (1/ndes> 0.0). With the exception of GSHA which desorbed from the pH 6.1 Plano silt loam (1/ndes= 0.15), desorption of HA and GSHA from other treatments was negligible (1/ndes= 0.0). Consequently, leaching of HA and GSHA in these and similar soils is not likely, due to high adsorption and low desorption.

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Mehr Quellen

Dissertationen zum Thema "Gshare"

Vávra, Jan. „Grafický simulátor superskalárních procesorů“. Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2021. http://www.nusl.cz/ntk/nusl-445476.

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Práce se zabývá implementací simulátoru superskalárního procesoru. Implementace se odvíjí od existujících simulátorů a jejich chybějících částí. Simulátor umí vykonávat instrukční sadu RISC-V, ovšem je umožněno přidání jakékoli RISC instrukční sady. Simulátor má deterministickou predikci skoku. Části procesoru lze upravovat. Součástí je i editor kódu pro danou instrukční sadu.

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Bücher zum Thema "Gshare"

Inc, Advanced Visual Systems. Gsharp getting started: Release 3.0. Manchester: Manchester Computing, University of Manchester, 1998.

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Inc, Advanced Visual Systems. Gsharp release notes: Release 3.0. Manchester: Manchester Computing, University of Manchester, 1998.

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Inc, Advanced Visual Systems. Gsharp user's guide: Release 3.0. Manchester: Manchester Computing Centre, 1998.

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Buchteile zum Thema "Gshare"

Kwak, Jong Wook, Seong Tae Jhang und Chu Shik Jhon. „History Length Adjustable gshare Predictor for High-Performance Embedded Processor“. In Computational Science and Its Applications - ICCSA 2006, 631–38. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11751632_69.

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Helffer, Mireille. „Chapitre IX. La cloche gshang“. In Mchod-rol, 215–31. Éditions de la Maison des sciences de l’homme, 1994. http://dx.doi.org/10.4000/books.editionsmsh.7344.

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Giardini, Domenico, Gottfried Gruenthal, Kaye Shedlock und Peizhen Zhang. „74 the GSHAP global seismic hazard map“. In International Geophysics, 1233–39. Elsevier, 2003. http://dx.doi.org/10.1016/s0074-6142(03)80188-2.

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„ddirroeucg te hdteavt en re ts duec it in of the hazard or a h re egrtthhe ro u ri g sk haasb so e c tt iear te udndweirtshtafnudtiunrge duction in vulnerability, or both. b ei can t es t r siusltthoefn actual his be human-in adtuucreadl . ortoern ical event. Disasters can diction, monitoring, mitiga G ti roev at i e ro r nmental causes and greatly reduce the frequency n a , n an em d d se pr pehp asis verit ayreodfnoens na stpucrra e danlv re o isasters. Many llautm ed epd ro is vaisdtee rs doofctuhmee case studie in dnetvae ti loonpio ng f s included in this countries. pre avnido us d d ev ro e u lo gphetd -e rm ly iassessment refers to the occu m rr aetnecseofotfhedrcoou st gshat. ndac Im lo ti psos ns aecsttsashsa ar otciaalegtle ow for classified as economic, social, and environmen etn“. In Droughts, 45. Routledge, 2016. http://dx.doi.org/10.4324/9781315830896-32.

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Konferenzberichte zum Thema "Gshare"

Bringer, Julien, Herve Chabanne, Melanie Favre, Alain Patey, Thomas Schneider und Michael Zohner. „GSHADE“. In the 2nd ACM workshop. New York, New York, USA: ACM Press, 2014. http://dx.doi.org/10.1145/2600918.2600922.

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Bringer, Julien, Othmane El Omri, Constance Morel und Hervé Chabanne. „Boosting GSHADE Capabilities“. In SACMAT 2016: The 21st ACM Symposium on Access Control Models and Technologies. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2914642.2914658.

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Funabiki, Ayako, Taisei Yabuki und Masahito Oguma. „Optimum Heating Pattern of a Ground Source Heat Reference Map“. In ASME 2015 9th International Conference on Energy Sustainability collocated with the ASME 2015 Power Conference, the ASME 2015 13th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2015 Nuclear Forum. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/es2015-49117.

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A ground source heat reference map (GSHRM) shows the minimum necessary thermal performance of the ground heat exchanger (GHE) of a ground source heat pump (GSHP) system. Thermal performance depends on thermal properties of the ground, the ground temperature profile, heat advection by groundwater flow, and the GHE operating pattern. This study modeled optimum heating and cooling modes for a GSHRM. First, continuous and intermittent operation modes were compared, and a standard operation time was defined. In a standard household GSHP system, the quantity of heat transferred from the ground depends on household energy demand, which is relatively constant. Once the demand is known, an operation mode is selected that can meet it. Continuous operation increased the total amount of heat exchanged over a period of time but lowered the heat flux at the GHE, whereas intermittent operation with relatively long stopped periods decreased the total amount of heat but did not greatly decrease the heat flux at the GHE. Second, energy-saving efficiency and cost factors were compared among intermittent operation modes. Operation costs consist of the electrical energy supplied to the heat and circulation pumps. At a given operation time, the energy supplied to the heat pump depends on its coefficient of performance (COP), whereas that supplied to the circulation pump depends on its pressure loss, hence on the GHE length. A long GHE has a higher initial cost. Thus, the optimum heating pattern must consider the configuration of the GSHP system, including energy-saving efficiency and cost factors.

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Zhang, Yaojun, Bonan Yan, Wenqing Wu, Hai Li und Yiran Chen. „Giant Spin Hall Effect (GSHE) Logic Design for Low Power Application“. In Design, Automation and Test in Europe. New Jersey: IEEE Conference Publications, 2015. http://dx.doi.org/10.7873/date.2015.1118.

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Chen, Zhanlong, Xin-cai Wu und Liang Wu. „GSHR-Tree: a spatial index tree based on dynamic spatial slot and hash table in grid environments“. In International Conference on Earth Observation Data Processing and Analysis, herausgegeben von Deren Li, Jianya Gong und Huayi Wu. SPIE, 2008. http://dx.doi.org/10.1117/12.815617.

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