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1
Bayliss, M. B., J. Ruel, C. W. Stubbs, S. W. Allen, D. E. Applegate, M. L. N. Ashby, M. Bautz et al. „SPT-GMOS: A GEMINI/GMOS-SOUTH SPECTROSCOPIC SURVEY OF GALAXY CLUSTERS IN THE SPT-SZ SURVEY“. IOP PUBLISHING LTD, 2016. http://hdl.handle.net/10150/622337.
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We present the results of SPT-GMOS, a spectroscopic survey with the Gemini Multi-Object Spectrograph (GMOS) on Gemini South. The targets of SPT-GMOS are galaxy clusters identified in the SPT-SZ survey, a millimeter-wave survey of 2500 deg(2) of the southern sky using the South Pole Telescope (SPT). Multi-object spectroscopic observations of 62 SPT-selected galaxy clusters were performed between 2011 January and 2015 December, yielding spectra with radial velocity measurements for 2595 sources. We identify 2243 of these sources as galaxies, and 352 as stars. Of the galaxies, we identify 1579 as members of SPT-SZ galaxy clusters. The primary goal of these observations was to obtain spectra of cluster member galaxies to estimate cluster redshifts and velocity dispersions. We describe the full spectroscopic data set and resulting data products, including galaxy redshifts, cluster redshifts, and velocity dispersions, and measurements of several well-known spectral indices for each galaxy: the equivalent width, W, of [O II] lambda lambda 3727, 3729 and H-delta, and the 4000 angstrom break strength, D4000. We use the spectral indices to classify galaxies by spectral type (i.e., passive, post-starburst, star-forming), and we match the spectra against photometric catalogs to characterize spectroscopically observed cluster members as a function of brightness (relative to m*). Finally, we report several new measurements of redshifts for ten bright, strongly lensed background galaxies in the cores of eight galaxy clusters. Combining the SPT-GMOS data set with previous spectroscopic follow-up of SPT-SZ galaxy clusters results in spectroscopic measurements for >100 clusters, or similar to 20% of the full SPT-SZ sample.
2
Cunha, Keyla Christy Christine Mendes Sampaio. „Fatores prognósticos em crianças e adolescentes portadores de Linfoma Não-Hodgkin“. Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/GMGS-7Z8EWU.
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This prospective/retrospective study comprises 98 children with non-Hodgkins lymphoma diagnosed between 1981 and 2006 (26 years) at the Hospital das Clínicas, Federal University of Minas Gerais. Prognostic factors for surviving the disease were analyzed. The immunohistochemistry contribution to increase the accuracy of the diagnosis was also evaluated. The majority of patients were males (male/female ratio 2.3). The median age at diagnosis was 70 months (range 8.4 to 189.5 months). Malnutrition was defined as a Z score -2 (2 standard deviation below the median for the reference WHO population). Taking into consideration the weight-for-age Z score, 20.2% of children were considered malnourished; for the height-for-age Z score the frequency was 8.2%. An abdominal mass was the commonest form of presentation (49%). WHO histologic classification and the staging devised by St. Jude Childrens Research Hospital was used throughout. Burkitts lymphoma was the most frequent histologic type (52%) and the majority of patients presented as advanced stage at diagnosis (70.2%). Follow up varied from 0.1 to 26.3 years (median 6.1y) for those who did not die. Complete clinical remission rate was 83.7%. The estimated probabilities of overall survival and event free survival at 5 years were 73% (SE 4.4%) and 72% (SE 4.7%), respectively. Death during induction (n = 14) were due to infections and severe metabolic disturbances. Relapses occurred in 5 patients, all localized to central nervous system (4 isolated and one combined with marrow relapse). Up to 1987 modified Sloan-Kettering LSA2L2 protocol was adopted for treatment (n = 20). From 1987 onwards BFM-based protocols were employed. In univariate analysis significant prognostic factors for dying were increased levels of serum uric acid and urea at diagnosis (P < 0.001 and P = 0.03, respectively), advanced stage (P = 0.014) and the way histologic specimen for diagnosis was obtained (partial versus total ressection; P = 0.03). Gender, age, nutritional status, histologic type, serum levels of LDH, type of treatment protocol, or response to treatment were not statistically significant prognostic factors. Improving the accuracy of the morphologic diagnosis with immunohistochemistry was not either associated with a higher probability of survival.A população deste estudo prospectivo/retrospectivo foi constituída de 98 crianças com diagnóstico de linfoma não-Hodgkin, diagnosticadas no Hospital das Clínicas da Universidade Federal de Minas Gerais no período de 1981 a 2006 (26 anos). Fatores prognósticos com possível influência na sobrevida foram analisados. Foi também avaliada a contribuição da imunohistoquímica na precisão do diagnóstico histológico. A maioria dos pacientes pertencia ao gênero masculino (relação masculino/ feminino igual a 2,3). A idade mediana dos pacientes ao diagnóstico foi de 70 meses (variação de 8,4 a 189,5 meses). Para caracterizar a desnutrição, adotou-se o ponto de corte de Z = -2 (dois desvios-padrão abaixo da mediana da população de referência da OMS). Em relação ao peso para a idade, 20,2% eram desnutridos e, em relação à estatura para a idade, 8,2%. A apresentação tumoral abdominal foi a mais frequente (49%). Foi utilizada a classificação histológica da Organização Mundial da Saúde e o sistema de estadiamento do St. Jude Childrens Research Hospital. O tipo histológico mais freqüente foi o linfoma de Burkitt (52%) e a maioria dos pacientes tinha estadio avançado (70,2%). O tempo de seguimento variou de 0,1 ano a 26,3 anos (mediana de 6,1 anos), para aqueles que não evoluíram para o óbito. A taxa de remissão clínica foi de 83,7%. A probabilidade estimada da sobrevida global e da sobrevida livre de eventos aos cinco anos foi de 73% ± 4,4% e de 72% ± 4,7% (n = 95). Os óbitos durante a indução, causados por infecções e distúrbios metabólicos e hemorragia, foram os mais frequentes (n=14). As recidivas ocorreram em cinco crianças, todas localizadas no sistema nervoso central, sendo que uma concomitantemente na medula óssea. Até 1987, o tratamento adotado foi o protocolo LSA2L2 modificado (n=20). A partir de 1987 foram adotados os protocolos de tratamento baseado nos estudos do grupo alemão BFM. Na análise univariada dos fatores desfavoráveis de prognóstico para a sobrevida, foram significativas as variáveis: dosagens elevadas de ácido úrico e de ureia ao diagnóstico (p < 0,001 e 0,03 respectivamente), estadiamento avançado (p = 0,014) e o método para obtenção do espécime histológico (ressecção parcial versus total; p = 0,03). Não foi observada nenhuma influência prognóstica significativa das variáveis gênero, idade, estado nutricional, tipo histológico, dosagem sérica de LDH, tratamento empregado e resposta ao tratamento. O aperfeiçoamento do diagnóstico com a imuno-histoquímica completa não se associou significativamente com uma melhor sobrevida.
3
Silva, Celia Maria da. „Rastreamento de crianças com Doença Falciforme pelo Doppler transcraniano em uma coorte de pacientes triados pelo Programa Estadual de Triagem Neonatal do Estado de Minas Gerais (PETN-MG) e acompanhados no Hemocentro de Belo Horizonte/MG - Brasil“. Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/GMGS-7Z8FW8.
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Neurologic complications in children with sickle cell anemia (SCA) are frequent. Approximately 11% of children and youths up to 20 years of age are at risk of stroke. Transcranial Doppler ultrasonography (TCD) is an important way of detecting risk of ischemic stroke. The aim of this study is to verify the incidence of stroke and altered TCD in children and determine possible risk factors. Methods: We analyzed a cohort of children selected by the Newborn Screening Program of MG, with SCA, born between March 1998 and December 2005 and followed at the Hemominas Foundation until May 2009. TCD was carried out in a randomized cross-section of 300 children. The examination followed STOP protocol, and used pulsed TCD with a 2 MHz probe. Children with mean blood flow velocity <170 cm/s for the middle cerebral artery, distal internal carotid and anterior cerebral artery were classified as low risk; if velocity was of 170-184 cm/s, lower intermediate risk; if velocity was of 185-199 cm/s, higher intermediate risk; and if of 200 cm/s, high risk. Results: mean age of 6.5 years (2-10y); 150 female.194 children (75.6%) were classified as low risk; 19 (7.4%) as lower intermediate risk; 7 (2.6%) as higher intermediate risk; and 8 (3.1%) as high risk; 11.2% of the examinations were considered inadequate. Those 7 children of high risk, after being submitted to confirmatory examinations, started a regimen of chronic transfusion and one of them of hydroxyurea. Another, considered low risk, had a hemorrhagic stroke (normal brain angiography). 13 children (4.8%) had suffered from ischemic stroke prior to having the TCD. Alterations in TCD or clinical stroke were observed in children with a lower mean age (p=0.002). The accumulated probability of having a stroke before age 10 was of 9.5%; of having stroke+altered TCD (intermediate and high risk) was of 38.4%. There was no difference between children with normal TCD and those with altered TCD+stroke in the anthropometric analysis (comparison between mean Z score at age 3), occurrence of acute splenic sequestration (p=0.13) and acute chest syndrome (p=0.16). Mean hemoglobin concentration was lower in children with altered TCD+stroke (p<0.001); mean white blood cell and reticulocyte counts were higher in children with altered TCD+stroke (p=0.006 and p>0.001, respectively). Upon multivariate analysis, mean reticulocyte count was the only significant variable (p=0.0002). We also observed a progressive increase of velocity in the basilar artery of children with higher velocity in the middle cerebral arteries (R= 0.59); p<0.001): 8 out of 25 children with altered TCD had basilar velocity >130 cm/s; out of the 186 low risk children, only one had basilar velocity >130 cm/s (p<0.001). Conclusions: frequency of clinical stroke was similar to that seen in the literature and that of high risk TCD, lower. The accumulated probabilities of altered TCD are high and require special attention in the following of children with SCD. High reticulocyte count was the most important factor in predicting erebrovascular disease. Basilar artery velocity >130 cm/s is another predictive factor for cerebrovascular disease.As complicações neurológicas na anemia falciforme (AF) são frequentes. Aproximadamente 11% dos pacientes até 20 anos podem ter acidente vascular cerebral (AVC). A realização de Doppler transcraniano (DTC) é importante meio para detecção de risco para AVC isquêmico. O objetivo deste estudo é verificar a incidência de AVC e de DTC alterado em crianças e determinar possíveis fatores de risco. Materiais e Métodos: Foi analisada uma coorte de crianças triadas pelo Programa de Triagem Neonatal de MG, com perfil FS, nascidas de 03/1998 a 12/2005 e acompanhadas no Hemominas de BH até maio de 2009. Para realização do DTC foi feito um corte transversal randomizado de 300 crianças. Os exames foram realizados segundo o protocolo STOP, utilizando-se o DTC pulsado, com sonda de 2 MHz. As crianças com velocidade média máxima (VMM) do fluxo sanguíneo cerebral <170 cm/s nas artérias cerebral média, carótida interna distal e cerebral anterior foram classificadas como de risco baixo; se VMM entre 170-184 cm/s, risco intermediário baixo; se VMM de 185-199 cm/s, risco intermediário alto e se 200 cm/s, risco alto. Resultados: a média de idade foi 6,5 anos (2-11a); 150 meninas. Foram classificadas como de baixo risco 194 crianças (75,6%); 19 risco intermediário baixo (7,4%); 7 risco intermediário alto (2,7%) e 8 risco alto (3,1%); 11,2% dos exames foram inadequados. Sete crianças com risco elevado, após exames confirmatórios, iniciaram regime de transfusão crônica e uma, hidroxiureia. Uma, com baixo risco, desenvolveu AVC hemorrágico (angiografia cerebral normal). Treze crianças (4,8%) haviam sofrido AVC isquêmico antes da realização do DTC. A ocorrência de DTC alterado ou AVC clínico foi observada em crianças com menor média de idade (p=0,002). A probabilidade acumulada de ter AVC até 10 anos de idade foi de 9,5%; a de AVC+DTC alterado (riscos intermediários + alto) de 38,4%. Não houve diferença entre as crianças com DTC normal e as com DTC alterado+AVC, quando se analisaram a antropometria (comparação de médias de escores Z aos 3 anos de idade), ocorrência de sequestro esplênico agudo (p=0,13) e síndrome torácica aguda (p=0,16). As médias de hemoglobina foram inferiores nas crianças com DTC alterado+AVC (p<0,001); as contagens de leucócitos e de reticulócitos foram superiores nas crianças com DTC alterado+AVC (p=0,006 e p<0,001, respectivamente). Em análise multivariada a média de reticulócitos foi a única variável significativa (p=0,0002). Observou-se aumento progressivo da VMM da artéria basilar nas crianças com VMM aumentada nas ACMs (definir a sigla) (R= 0,59; p<0,001): 8 das 25 crianças com DTC alterado possuíam VMM basilar >130 cm/s; entre as 186 com baixo risco, apenas 1 possuía VMM basilar >130 cm/s (p<0,001). Conclusões: a frequência de AVC clínico foi semelhante à da literatura e a de DTC alto risco, inferior. As probabilidades acumuladas de DTC alterado são altas e requerem atenção especial no seguimento de crianças com AF. A contagem elevada de reticulócitos foi o fator mais importante para predizer doença cerebrovascular (DCV). A VMM na artéria basilar >130 cm/s é mais um fator preditivo de DCV.
4
Paula, Priscilla Barreto. „Correlação entre o pico do fluxo da tosse e os parâmetros clínicos e funcionais nas doenças neuromusculares“. Universidade Federal de Minas Gerais, 2010. http://hdl.handle.net/1843/GMGS-8DQUUT.
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Durante a Faculdade de Fisioterapia, tive a oportunidade de acompanhar o caso de uma criança com distrofia muscular de Duchenne, época em que fui monitora dos alunos do 8º período no ambulatório de fisioterapia respiratória. Nessa ocasião, intrigou-me o motivo pelo qual não foram abordados pelos professores os aspectos relevantes da avaliação respiratória e o tratamento de pacientes com doenças neuromusculares (DNM). Posteriormente, durante a especialização em fisioterapia respiratória, integrei a equipe de doenças neuromusculares do Hospital das Clínicas da UFMG e, a partir daí, iniciei o acompanhamento de crianças e adolescentes com diferentes diagnósticos de DNM. Pude familiarizar-me com a medida do pico do fluxo da tosse (PFT), ainda pouco utilizada por profissionais da área da saúde. Logo surgiu a necessidade de estudar de forma mais detalhada a literatura disponível sobre o pico do fluxo da tosse e a abordagem pneumológica nesse grupo de doenças, entretanto, algumas dúvidas ainda não conseguiam ser respondidas pelos estudos, tais como: durante a rotina de acompanhamento a essas crianças e adolescentes, quais são os métodos de avaliação respiratória mais indicados? Qual a periodicidade dessas avaliações? Qual a relevância da medida do pico do fluxo da tosse e sua correlação com os parâmetros de avaliação clínico-funcional nesses pacientes? Essas questões, aliadas ao fato de que a cada dia número mais elevado de crianças e adolescentes é referido aos serviços de pneumologia e neurologia pediátrica do Hospital das Clínicas, estimularam o desenvolvimento desta pesquisa.
Para tanto, a equipe investiu em equipamentos que possibilitassem a avaliação respiratória das crianças e adolescentes com DNM e, ainda, permitiu o desenvolvimento desta pesquisa com vistas a não somente contribuir para o conhecimento sobre a avaliação respiratória nas DNMs, mas também possibilitar a implementação de acompanhamento pneumológico a esses pacientes com equipamentos específicos e indispensáveis ao propósito. Portanto, o presente estudo tem como objetivo avaliar a correlação do PFT com os parâmetros clínicos e funcionais de crianças e adolescentes com DNM, uma vez que o equipamento no qual se mede o PFT é um instrumento de medida de baixo custo financeiro, portátil e de fácil manuseio. Essas características, aliadas às perspectivas futuras de tratamento dessas doenças, tornam o PFT de importante valor clínico na monitoração de crianças e adolescentes com DNM de forma acessível a toda a equipe multidisciplinar, ao próprio paciente e seus familiares.
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Rezende, Ludmila Teixeira Fazito. „A Triagem neonatal auditiva: conhecimento do Pediatra de Minas Gerais“. Universidade Federal de Minas Gerais, 2009. http://hdl.handle.net/1843/GMGS-7ZSSM4.
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The main part of the newborn hearing screening programs is the early diagnosis of hearing problems and the appropriate educational intervention. So that the screening programs can be successful, it is unquestionable the participation of pediatricians, because they have an important role in the parents decisions related to their newborn child. This study aimed to the investigation of the pediatricians knowledge about the correct procedures, the used techniques and the early diagnosis of the hearing problems in newborns, besides identifying the possible factors related to their knowledge about the newborn hearing screening and its interfaces in Childs Health. It is a cross-section study, performed by inquiry of 93 pediatricians associated to the Minas Gerais Pediatrics Association and through questionnaires answered by 34 pediatricians who participated in a congress of pediatric otolaryngology in Minas Gerais. The variables that provided information about the pediatricians profiles were: years of graduation, which college the doctor graduated from, type of specialization, place and year of the conclusion of the residency, type of pos-graduation and year of its conclusion, environment of work and where their knowledge of hearing and its problems were taken. The variables that investigated the doctors knowledge about the hearing screening programs and its interfaces were: the knowledge about which is the best age to perform the screening, the hearing diagnose and the use of the hearing equipments, the knowledge of the risk factors to deafness and the identifications of which children must pass through the program, the methods of evaluation available and the best moment to perform the screening, which conduct is more appropriated in cases of altered screening and normal triage, educational interventions available, justification to perform the early diagnosis and the role of the pediatrician in those cases. It was analyzed as well if the pediatrician had the knowledge of the difference between the deaf children diagnosed and treated precociously and children with normal hearing, the age to initiate the speech pathologist therapy and their interest to obtain more information about the subject and which are the best ways to get that information. According to the results obtained, only 47 (37%) of de pediatricians were considered knower of the subject. 98% demonstrate that they have knowledge about the possibility of evaluating hearing before 30 days of life, but do not know to identify which exams are available to this evaluation, and only 59% of them send all of the newborns to the hearing screening. Most of the pediatrician do not know until which age the diagnosis must be concluded and just a few (8%) know that a baby with less than 30 days can use hearing aids. There were no statistics differences between pediatricians who know the subject and those who don´t related to the average of time of graduation (p=0,52), nature of the institution of graduation (0,06), period of conclusion of the residency (p=0,17), kind of pediatrics specialization (p=0,76), nature of their work environment (p=0,10), knowledge of which age is possible to evaluate the babies hearing (p=0,18) and knowledge that all of the children must pass through the hearing screening process (p=0,07). The other variables researched demonstrate differences statistically significant between knowers and unknowers. The results of this study suggest a real necessity to establish a more effective way to divulgate to the pediatricians the advantages of the newborn hearing screening, the techniques available to its realization and, mainly, which conducts are more appropriate to the after screening steps. There were no specific characteristics found in the pediatricians profiles that could improve the fact of being a knower or unknower of the subject. Information about the importance of the screening to the development of the childs oral language and the necessity that all of the children must pass through the screening; tend to be common knowledge of the pediatricians. The other variables analyzed suggest to change the knowledge of the pediatricians, emphasizing the importance of specific orientations about the theme, due to the fact that most of them (63%) were classified as unknowers of the procedures and conducts involving the screening.O principal papel dos programas de triagem auditiva neonatal é o diagnóstico precoce dos problemas auditivos e a intervenção educacional adequada e em tempo hábil. Para que os programas de triagem sejam bem sucedidos é indiscutível a necessidade da participação dos médicos pediatras, pois exercem importante papel na tomada de decisões dos pais em relação aos seus filhos recém-nascidos. Este estudo objetivou investigar o conhecimento de pediatras sobre os procedimentos adequados e as técnicas utilizadas para a detecção e o diagnóstico precoce dos problemas auditivos em neonatos além de identificar os possíveis fatores relacionados com o conhecimento deles sobre a triagem auditiva neonatal e suas interfaces na área da saúde da criança. Trata-se de um estudo de corte transversal realizado através de inquérito por meio eletrônico com 93 pediatras associados da Sociedade Mineira de Pediatria e através de questionários respondidos por 34 pediatras participantes de um congresso mineiro de otorrinopediatria. As variáveis que forneciam informações sobre o perfil dos pediatras foram: tempo de formado, faculdade que se graduou, tipo de especialidade, local e ano de conclusão da residência, tipo de pós-graduação e ano de conclusão, local de trabalho e onde adquiriu seus conhecimentos sobre audição e sua deficiência. As variáveis que investigavam o conhecimento médico sobre a triagem auditiva e suas interfaces foram: o conhecimento sobre a melhor idade para realizar a triagem auditiva, o diagnóstico audiológico e o uso do aparelho auditivo. Também investigavam o conhecimento dos fatores de risco para surdez e identificação de quais crianças devem, obrigatoriamente, passar pela triagem, os métodos de avaliação disponíveis e melhor momento para realizar a triagem, qual a conduta mais adequada em casos de triagem alterada e triagem normal, intervenções educacionais disponíveis, justificativa para realizar o diagnóstico precoce e o papel do pediatra nesta atuação. Ainda foi pesquisado, se o pediatra possuía conhecimento da equiparação do desenvolvimento da criança surda diagnosticada e tratada precocemente com a criança normal e idade para iniciar terapia fonoaudiológica e o interesse deles em obter maiores informações sobre o assunto e qual a melhor forma de obter tais informações. De acordo com os resultados obtidos apenas 47(37%) dos pediatras foram considerados conhecedores do assunto. 98% demonstram ter conhecimento sobre a possibilidade de se avaliar a audição antes dos 30 dias de vida, mas não sabem identificar quais os exames disponíveis para esta avaliação e apenas 59% deles encaminham todos os recém-nascidos para a triagem. A maioria dos pediatras desconhece até qual idade o diagnóstico deve preferencialmente ser concluído e poucos (8%) sabem que um bebê com menos de 30 dias pode usar aparelhos auditivos. Não houve diferenças estatísticas entre pediatras conhecedores e não conhecedores quanto à média de tempo de formado (p=0,52), natureza da instituição de graduação (p=0,06), período da conclusão da residência (p=0,17), tipo de especialidade pediátrica (p=0,76), natureza do local de trabalho (p=0,10), conhecimento de qual idade é possível avaliar a audição de bebês (p=0,18) e conhecimento de que todas as crianças devem passar pelo rastreamento auditivo (p=0,07). As demais variáveis pesquisadas demonstraram diferenças estatisticamente significativas entre conhecedores e não conhecedores. Os achados deste estudo sugerem uma real necessidade de se estabelecer uma forma mais efetiva de divulgar para os pediatras as vantagens da triagem auditiva neonatal, as técnicas disponíveis para sua realização e principalmente quais as condutas mais adequadas para as etapas pós-triagem. Não foram encontradas características específicas no perfil dos pediatras que pudessem favorecer o fato de ser conhecedor ou não do assunto. Informações sobre a importância da triagem auditiva para o desenvolvimento da linguagem oral da criança e a necessidade de que todas as crianças devam passar pela triagem tendem a ser de conhecimento geral dos pediatras. As outras variáveis analisadas sugerem influenciar no conhecimento dos pediatras enfatizando a importância de orientações específicas sobre o tema, uma vez que a maioria (63%) foi classificada como não conhecedora dos procedimentos e condutas envolvendo a triagem auditiva.
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Ghose, Rana Janak. „Regulating GMOs in India : pragmatism, politics, representation, and risk“. Thesis, University of Sussex, 2011. http://sro.sussex.ac.uk/id/eprint/7579/.
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At the core of any effort by a nation state to regulate new technologies for public release is an implicit navigation of uncertainty. The case of Bt cotton in India presents a very timely and pragmatic example of how nation states grapple with uncertainty in a regulatory context. While much attention has been given to how government actors form regulation, far less is given to how actors outside of the government spheres act as catalysts for regulatory reform. In practice, it is often these parties that drive regulation as a process. The question is how. This paper outlines the findings of fieldwork conducted in India between March 2007 and July 2009 in addressing this central question: what does regulation really mean in a context where new technologies burdened with uncertain consequences are introduced? How do preferences, decisions, and regulatory norms adapt to this introduction based on the interactions of a multitude of parties acting on multiple framings of understanding what risk means? The conclusion is that regulation – in the context of Bt cotton in India - is far from a set of government policies derived from scientific measures of risk assessment. Civil society, firms, and farmers themselves all have tremendous influence on how a nation state navigates uncertainty in a regulatory context. It is a process forged on risk interfaces, where constructions of risk both complement and oppose one another. The actors involved enter these spaces, invited or otherwise. What the government may have initially imagined as ‘regulation' is subject to multiple technical, economic, and political framings of risk from each actor. As a result, regulation is a coevolutionary, co-constructed process. This process of negotiating these spaces is what regulation really means.
7
Kluz, David. „Systém pro snadné sledování a vyhodnocování výrobních procesů (GMES)“. Master's thesis, Vysoké učení technické v Brně. Fakulta podnikatelská, 2013. http://www.nusl.cz/ntk/nusl-223969.
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This thesis analyzes the company Hyundai Dymos English due to the awareness of management of the production status. During the work are identified important production information to be transferred within the company. In this work is designed and implemented a system for efficient transfer of information within the company using Web portals and applications for mobile phones.
8
Everett, Kirstin Elizabeth. „Analysis of the WTO Dispute on Trade with GMOs“. Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-10854.
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In 2003 the United States filed an official complaint against the European Community at the World Trade Organization in regards to the ban imposed on GM crops within the EU, saying that there was no scientific defense for their point of view, and this had created barriers to trade. After one of the longest dispute settlement in WTO history, the body sided with the US and deemed the ban to be restricting free trade. Conflicting research on the safety of GM crops has further complicated the matter and many members of the EU are still choosing to ban GM crops in defiance of the WTO ruling.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „GMS Medizinische Informatik, Biometrie und Epidemiologie“. German Medical Science, 2005. https://ul.qucosa.de/id/qucosa%3A12911.
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Vasan, Dimple. „The identification and characterisation of the gmhD gene in Campylobacter jejuni“. Thesis, University of Canterbury. Department of Plant and Microbial Sciences, 1999. http://hdl.handle.net/10092/4234.
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Lipopolysaccharides (LPS) are an integral component of the Gram-negative bacterial
outer membrane and play an important role in maintaining cellular integrity. L-glyceroD-
mannoheptose (Hep) is a primary component of the LPS core region and appears to be
synthesised from sedoheptulose-7-phosphate via a four-step process. In Escherichia coli,
the final step of Hep synthesis is performed by ADP-L-glycero-D-mannoheptose-6-
epimerase, encoded by the gmhD gene. The initial aim of this study was to characterise
Hep biosynthesis in Campylobacter jejuni. An E. coli K12 isolate defective in gmhD
provided a model with which to study Hep biosynthesis in C. jejuni, in particular the last
step in Hep biosynthesis catalysed by the enzyme GmhD. To test whether a functional
equivalent of this enzyme is present within Campylobacter, a C. jejuni plasmid
expression library was introduced into the E. coli K12 gmhD strain. Restored LPS was
assessed by measuring changes in novobiocin sensitivity and LPS profiles of the
transformants. Partial nucleotide sequencing of the cloned C. jejuni DNA insert revealed
an incomplete ORF that, when translated into amino acid sequence, displayed strong
similarity to the 3' end of the GmhD protein from Helicobacter pylori, Aquifex aeolicus,
and Haemophilus injluenzae. Transformation of the E. coli K12 gmhD mutant with a
plasmid (PDV08) containing a 350 bp in-frame deletion of a C. jejuni gmhD allele failed
to restore novobiocin resistance or wild-type LPS expression. Based on this evidence,
the gene present in C. jejuni has been named gmhD. Nucleotide sequence analysis
indicated that one other gene involved in Hep biosynthesis was likely to be present within
this insert (gmhC). Analysis of the assembled gmhD DNA sequence from the C. jejuni
genome project revealed an ORF of 954 nucleotides, encoding a protein of 318 amino
acids with a calculated mass of 36.0 kDA. Amino acid sequence analysis of the C. jejuni
GmhD protein revealed an ADP-binding site as found in the GmhD protein of E. coli,
Salmonella typhimurium, and Neisseria gonorrhoeae. Growth of the transformants in
minimal and nutrient-rich media revealed reduced growth; however, this might be
insignificant. Insertion of a kanamycin resistance cassette into pDV08 followed by gene
replacement onto the C. jejuni chromosome by homologous recombination would have
completed the construction of a null mutation in gmhD of C. jejuni. However, due to
time constraints this was not completed.
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Tuohy, K. „Measurement of DNA transfer in the gut using in vitro and in vivo models“. Thesis, University of Surrey, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322465.
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Wanlass, Michael David. „Risk Perception, Bias, and Resistance to New Food Tech: The Case of GMOS“. Thesis, North Dakota State University, 2020. https://hdl.handle.net/10365/31732.
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GMOs are very controversial among consumers. Many fear that they may have risks scientists are not accounting for. Some GMOs, such as GMO soybean oil, have concerns over their processing methods as well. Traditional risk assessments that only account for hazard do not take these fears into account. Including risk perception, bias, and resistance is a way to account for consumers’ fears. Risk perception, bias, and resistance together create an aggregate that in turn affects willingness-to-purchase. A discrete choice experiment assessed risk perception of, bias towards, and resistance towards GMOs. Respondents revealed their preferences between buying GMO or non-GMO soybean oil, each with a selection of attributes. Stated preferences on a series of scales showed their risk perception of, bias towards, and resistance towards GMOs. On the whole the results showed that risk perception, bias, and resistance together were significant factors on respondents’ choice of GMO soybean oil.
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Wilke, Elena [Verfasser]. „Die Pflichtmitgliedschaft juristischer Personen in Zahnärztekammern - dargestellt am Beispiel von Zahnarzt-GmbHs / Elena Wilke“. München : Verlag Dr. Hut, 2010. http://d-nb.info/1009484982/34.
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NAKAGAWA, Seiichi, Souta HAMAGUCHI und Norihide KITAOKA. „Noisy Speech Recognition Based on Integration/Selection of Multiple Noise Suppression Methods Using Noise GMMs“. Institute of Electronics, Information and Communication Engineers, 2008. http://hdl.handle.net/2237/14965.
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Moroso, Mario. „The institutionalisation of GMOs : institutional dynamics in the GM regulatory debate in the UK, 1986-1993“. Thesis, University of Exeter, 2008. http://hdl.handle.net/10036/72214.
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This thesis analyses the process of institutionalisation of the concept of genetically modified organism (GMO) in the UK between 1986-1993. The existing accounts of the GM debate have focussed on either the 1970s or the 1990s. Very little, however, has been said about the 1980s, long before that of GMOs became a popular issue. Through a detailed examination of the PROSAMO initiative – a series of experiments aimed at determining the environmental impact of GMOs with a regulatory purpose in mind – this thesis have been able to explore the important but rather neglected role of the UK dominant institutions in the historical development of the debate over the release of GMOs into the environment. In analysing the way ‘GMO’ institutionalised between the late 1980s and early 1990s, this thesis shows that the concepts of risk and uncertainty – which have dominated the GM debate – need to be conceived as collective constructs that are used strategically in order to pursue various objectives related to the context in which people using them operate. It is also argued that the legitimate use of these concepts is bound to the credibility and the authority of science. These considerations have stimulated some reflections on the nature and role of regulation in the GM debate. In particular, it is argued that the move from a voluntary system of controls to a statutory one represents a move from an epistemic community approach to policy-making to a logic of bureaucratic politics, in which the literal interpretation of rules became a solution to political disagreement. As rule following became a political requirement, GMOs became a bureaucratic issue and scientists turned into bureaucrats. Within these changes, the role of scientific expertise in the definition of GMOs decreased. From this point of view, the way ‘genetic modification’ and GMO institutionalised gave rise to new practices and behaviours that turned around GMO as a controversial but nevertheless stable category.
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Goodman, Jessica Lauren. „Defining symbolic spaces in response to a globalized world : incorporating GMOs and segregating markets in Mexican agriculture“. Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/16126.
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Developing countries are increasingly adopting agricultural biotechnologies to meet domestic objectives of food security, industrialization, increasing commodity exports, and international competitiveness. Yet, developing country policies lack coherence and are often conflicting and contradictory. Prevalent theories on the adoption of such technologies focus on trade relationships, regime membership, institutional capacity, consumer and producer acceptance, and environmental concerns. This thesis argues there is a need to move beyond static or uni-causal explanations. It proposes a framework that incorporates notions of symbolic politics as essential components. Incoherent national policies reflect national objectives and international constraints, as well as the concerns of society as expressed through resistance campaigns. The latter seek to influence national policies by framing GMOs in relation to broader societal concerns. By organizing resistance around a specific resource or symbol associated with conceptualizations of culture, identity, and autonomy, such movements are able to alter the meanings associated with GM crops. Thus, it is through the mobilization of symbolic politics that organized opposition is able to succeed in influencing national legislation in areas dominated by trade concerns, material interests, and power politics. This argument is explored though a narrative analysis of policy development in Mexico. Despite its history of promoting biotechnologies, it has not yet introduced GM maize due to effective resistance, as maize is a powerful symbol throughout the nation. This thesis also briefly considers the cases of Brazil and India as useful contrast cases that allow us to draw larger implications.
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Ghodoosipour, Behnaz. „Three dimensional groundwater modeling in Laxemar-Simepevarp guaternary deposits“. Thesis, KTH, Mark- och vattenteknik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-171841.
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Groundwater is one of the main sources of drinking water in Sweden. Groundwater fluctuations and the detection of flow direction is of significant environmental importance especially when there is a risk for transport of contaminations. The Swedish Nuclear Fuel and Waste Management Company (SKB) has done detailed geotechnical investigations at two potential sites for a final nuclear waste deposition. This report presents the results from groundwater modeling in quaternary deposits in one of these sites. A steady state three dimensional groundwater model was developed for a 71 km2 large area in the Laxemar-Simpevarp, 320 km south of Stockholm close to the nuclear power plant Simpevarp. For this purpose, the Groundwater Modelling System (GMS) was used. The model uses finite difference method to solve the partial differential equation for the water movement with constant density through porous medium. The main objectives were to predict the groundwater heads and the flow directions, and to study the water balance. A conceptual model approach was used by creating five heterogynous soil and rock layers. GIS (Geographic Information System) was used to create top and bottom elevation of the layers by interpolating the GIS data. The model was calibrated using observation data in groundwater monitoring wells and the optimum values for recharge and hydraulic values were found. The numerical simulation was done for two different grid sizes (511×316 m2 and 255×158 m2) referred to coarse and fine grid model respectively. Results from the multilayer model showed flow towards the sea and in the quaternary deposits but not in high elevated rocks. The water balance in the multilayer model was satisfied in both grid sizes. The 3D groundwater model GMS was successfully applied to the large Laxemar-Simpevarp region. The choice of grid size was studied and better agreements between observed and simulated groundwater heads were found in the finer grid model. Large simulation errors in some of the observation wells can indicate GMS model’s weakness in modelling thin soil layers and large variance in topography.
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Clark, Alexandra Lynn, und Alexandra Lynn Clark. „A groundwater flow model of Indian Wells Valley, California, Utilizing GMS with GIS applications“. Thesis, The University of Arizona, 1999. http://hdl.handle.net/10150/626875.
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The sustainability of a potable groundwater supply in the regional aquifer of
Indian Wells Valley, California, is threatened by overdraft and by induction of
contaminated upper aquifer waters into the lower, regional aquifer. A three layer
MODFLOW groundwater model is developed in GMS (Groundwater Modeling System)
to enhance understanding of the hydro logic flow regime and to serve as a groundwater
management tool. The steady-state model is calibrated with water level measurements
collected during 1920 and 1921. Water level data spanning several decades are used in
transient model calibration. Calibration is by trial and error adjustment of the
transmissivity with subsequent recharge refinement. Model simulated heads agree with
observed heads in most regions within ten feet, except for the southwest, which may
require additional field investigation. The model suggests that less than 5000 acre
feet/year of recharge may supply the valley, compared with previous model estimates of
9840 acre-feet/year.
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Loftis, David R. „Hydrogeologic Analysis and Data Collection for the Oneida Tie Yard Site“. Master's thesis, Virginia Tech, 1999. http://hdl.handle.net/10919/46531.
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During the 1950's and 1960's a railroad yard located in Oneida, Tennessee, was used as a creosote treatment facility for railroad ties. After the cross-ties were treated with creosote, the excess creosote was stored in an holding pond located about 100 feet north of Pine Creek (Fetterolf 1998). In 1990, during a creek modification project, creosote was discovered seeping through the banks of Pine Creek. The creosote had leached through the bottom of the pond and migrated towards the creek.
In 1997, the Tennessee Department of Environment and Conservation authorized a remedial strategy prepared by Geraghty & Miller, Inc (Fetterolf 1998). The strategy involved the use of phytoremediation and a previously installed interception trench system. The primary goals of the phytoremediation plan are to stimulate biodegradation and to decrease groundwater flow, thus minimizing the migration of the contaminant into Pine Creek. Poplar trees were selected for the phytoremediation plan and were planted in two sections.
The objectives of this report involved analyzing the hydrogeology of the Oneida, Tennessee site and organizing the collected data for the purpose of evaluating the impact of the phytoremediation and interception trench systems on the aquifer. The water level data was used to evaluate water level and hydraulic gradient changes due to evapotranspiration, rainfall, and groundwater extraction. It was obvious from the water level and rainfall comparison plots that the rainfall has a measurable effect on the water table elevation (i.e. groundwater flow). Some areas may be less affected because the coal layer has a tendency to decrease recharge. Meanwhile, the interception trench lowers the water level around the trench. The decrease in head occurs before and after the trench, thus the water level forms a "v-shape" at the trench. This "v-shape" lends to the notion that the hydraulic gradient also slopes towards the trench in both directions. As for the phytoremediation, there was not sufficient evidence to suggest that the water levels were being lowered by evapotranspiration. This was expected since the poplar trees were had only completed their second growing season.
GMS MODFLOW was used to predict the effects on the water table due to the phytoremediation and the interception trench systems. The calibrated model did an adequate job in simulating the site when the interception trench was not in operation and the trees were not in their growing season. By using variable recharge in some areas, the results are expected to improve. For example, it is important to know the location of the coal layer so this area can be given a lower recharge value than the other areas in the model. As for the trench model, the simulated heads were much lower than the observed heads, which emphasizes that using wells is not the best method to simulate the interception trench. In the future, a transient model should be used to simulate the site with the trench operation, and the drain package could be used to model the trench itself. Meanwhile, the ET model was a valuable simulation, because it illustrates how effective the poplar trees can be even under conservative conditions. With an assumed root zone of just 3 feet and a maximum potential evapotranspiration rate of 4.6 gallons per day per tree, the majority of the site will experience the dry conditions expected.Master of Science
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Touiti, Takoi. „Les stratégies d'implantation en grandes et moyennes surfaces (GMS) : le cas des produits de terroir“. Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAB006/document.
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La diversification de l’offre des produits de terroir oblige les distributeurs à s’interroger sur leur implantation en magasin. Cette thèse propose de réfléchir sur la décision de l’implantation des produits de terroir dans le contexte français en adoptant une approche inter-catégorielle, au niveau général du magasin. Cette recherche étudie le rôle des stratégies d’implantation dans l’accroissement de l’accessibilité et de la facilité d’achat des produits de terroir en magasin, d’une part, et dans l’augmentation de la performance financière, d’autre part. Pour ce faire, une étude qualitative exploratoire ainsi qu’une expérimentation dans un magasin ont été menées sur les catégories de produits de terroirThe diversification of the offer of terroir products forces distributors to question their allocation in the store. The thesis proposes to reflect on the allocation of terroir products in the French context by adopting an inter-categorial approach, at the general level of the store. This research examines the role of shelf space allocation strategies in increasing the accessibility and ease of purchase of terroir products in-store, on the one hand, and in increasing financial performance, on the other hand. Therefore, both an exploratory qualitative study and an experiment in a store have been conducted for the categories of terroir products
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Pettersson, Kevin. „Groundwater Movement and PFAS Transportation in the Vreta-Bålsta Esker“. Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423952.
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Håbo municipality is looking for alternative drinking water sources for its residence city of Bålsta. One possible source is the Vreta-Bålsta esker located northeast of Bålsta, which could be used for artificial infiltration and extraction of groundwater. Located on this esker is an area called Dragets industrial area, in which several objects of potential contamination have been identified. One of these is a Landfill located in the northern part of the industrial area in which the local fire fighting forces has used this area for training exercises. During these exercises they have used aqueous film forming foams (AFFFs) containing Per- and polyfluoroalkyl substances (PFAS). Some PFASs have demonstrated adverse health effects already at low concentrations and no more than 90ng l-1 is recommended in Swedish drinking water. In order to assess the suitability of the esker as a source for drinking water a model of the esker was created inside the program GMS (Groundwater modeling system). In GMS the package MODFLOW was used to create a groundwater flow model, and the package MT3DMS was used for contamination transport of PFAS from the landfill. The finished model showed a groundwater divide located in the central parts of Dragets industrial area, with the water either running south toward Lake Mälaren or north towards Lilla Ullfjärden. In total three different PFAS species were used in the transport model with the abbreviations PFOS, PFPeA and PFBA. The transport model was created as a point source to see the transport behavior of PFAS from the landfill. This showed that all the contamination transport that occurred would transport the PFAS north towards Lilla Ullfjärden. Based on this result this would mean that a use for artificial infiltration and extraction of groundwater in the southern part of the esker would not pose a contamination risk from the landfill.
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Melo, Saulo Menezes de. „Estratégia de adaptação local na simulação de escoamentos bifásicos em meios porosos“. Universidade Federal de Pernambuco, 2014. https://repositorio.ufpe.br/handle/123456789/17095.
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CAPEs
Neste trabalho, abordamos o processo de adaptação de malhas via “remeshing”, a adap-tação de malhas não estruturadas é usada aqui como uma ferramenta de alto desempe-nho que visa simultaneamente garantir a qualidade do resultado e reduzir o tempo com-putacional envolvido em toda a simulação. Usamos um simulador numérico de escoa-mento óleo-água em reservatório de petróleo em duas dimensões. Os fluidos e a rocha reservatório são tidos como incompressíveis e não se considera variações térmicas. Um método de volumes finitos centrado nos nós e baseado em uma estrutura de dados por arestas é empregado na discretização das equações de pressão e de saturação. Uma for-mulação agregada IMPES (Implicit Pressure Explicit Saturation) é utilizada para resol-ver as variáveis de saturação e de pressão. Aproximações de baixa e alta ordem na eq. de saturação e seus efeitos na propagação dos erros é calculada. A cada avanço no tem-po, novos campos de saturações e de pressões são avaliados e, em seguida, a qualidade destes resultados é estimada. Isto é realizado por meio de um estimador de erros basea-do na hessiana dos campos de pressão e de saturação, os quais são usados para calcular os erros local e global referentes a cada campo. Estes erros são comparados a uma tole-rância que irá definir se a malha deve ou não ser adaptada, onde e em que grau de refi-namento. O método de adaptação desenvolvido é o do “remeshing” ou redefinição de malhas, que se baseia na reconstrução total ou parcial da malha. A redefinição da malha é feita com o gerador open-source Gmsh que possibilita a criação da malha com contro-le do grau de refinamento local através da malha de “background”. Após a adaptação, os campos de pressão e de saturações são interpolados da malha anterior para a nova malha. Métodos lineares, quadráticos e adaptativos de interpolação são explorados e avaliados. Para um mesmo instante de tempo, o processo de adaptação se repete até que a qualidade dos resultados atinja a tolerância exigida. Para a integração e conformidade de todas estas etapas foi desenvolvido um software na linguagem C++ usando a biblio-teca para gerenciamento de malhas FMDB (Flexible Distributed Mesh Data Base). Foi efetuado um estudo da qualidade dos resultados obtidos e da eficiência da simulação quando da utilização do procedimento de adaptação de malhas desenvolvido em simula-ções de escoamento monofásico e bifásico óleo-água em meios porosos usando malhas não estruturadas 2D triangulares, considerando meios homogêneos e heterogêneos, iso-trópicos e anisotrópicos, comprovando a robustez da metodologia implementada nas simulações efetuadas.
In this work, we address the mesh adaptation process using "remeshing" tehcnique. The adaptation of unstructured meshes is used here as a high performance tool intended both to ensure the quality of the result and to reduce the computational time involved in the whole simulation. The numerical simulation are performed using a two dimensional two phase flow numerical simulation of oil and water in porous media. Fluids and reservoir rock are considered incompressible and does not consider thermal variations are consid-ered. A cell centered finite volume method using an edge based data structure used for of the error the discretization of the pressure and saturation equations. The IMPES for-mulation (Implicit Pressure Explicit Saturation) composes the structure of the simula-tor.The hyperbollic saturation equation is discretized using either a first or higher order aproximation and the effect of such choice is analysed. After advancing the solution in time the obtained result is analysed using an a-posteriori erro indicator. At each time step a new field of saturation and pressure is evaluated, and then, the quality of results is assessed. This is accomplished by means of an estimator based on the Hessian of the fields of pressure and saturation, which are used to calculate both the local and global errors for each field. These errors are compared to a tolerance that will define whether or not the mesh must be adapted where the mesh density required. The adaptive method developed is refered to as "remeshing" and considers either total or partial reconstruc-tion of the mesh. The remeshing is done with the open-source mesh generator named Gmsh that enables to build mesh containing the level of refinement through the mesh refinement "background." mesh. After adaptation, the fields of pressure and saturations are interpolated from the previous mesh to the new mesh. Linear and quadratic interpo-lation methods are explored and evaluated. For the same level of time, the adaptation process is repeated until the quality of results reached the required tolerance. For the integration and accomplishement of all these steps a software was developed in C + + language and using the library for unstructured mesh management FMDB (Flexible Distributed Mesh Data Base) mesh. A study of the quality of the analysed results and of the efficiency of the simulation was performed when using the adaptive mesh procedure developed through the analysis of single-phase flow and two-phase oil-water in porous media using 2D models with triangular unstructured meshes. The analysed examples considers homogeneous and heterogeneous media, isotropic and anisotropic, demon-strating the robustness and efficiency of the methodology implemented for the cases analysed in the simulations performed.
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Moosajee, Shaheda. „Exploring the construct-related validity of the personal-social subscale of the Griffiths Mental Development Scales-extended revised (GMDS-ER)“. Thesis, Nelson Mandela Metropolitan University, 2007. http://hdl.handle.net/10948/572.
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Child assessment has become imperative today as parents and teachers recognize the need for early diagnostic assessments to adequately cater for children’s’ diverse and growing needs so that children can benefit from services and attention in a psychological or educational setting. The Griffiths Mental Development Scales, an established and well-researched instrument is reported to be one of the most carefully designed measures of child development . Studies in various parts of the world have demonstrated that the Griffiths Scales are applicable to diverse populations and that they tap experiences that are common to different cultures. The recent revision and restandardisation of the Griffiths Mental Developmental Scales-Extended Revised (GMDS-ER) has necessitated investigations into its psychometric properties. In view of the important role that assessment measures play in the early identification of developmental delays, it is important that assessment measures are reliable and valid for their intended purpose(s). This study, which is part of a larger research project, attempted to explore and add further evidence of the construct validity of one of the six Subscales of the GMDS-ER, namely the Personal-Social Subscale (Subscale B). An exploratory-descriptive design using a triangulation approach was utilized to explore the construct validity of the Personal-Social Subscale. A nonprobability purposively selected sample of 18 experts working with children participated in the facet analysis to identify the constructs underlying Subscale B (the qualitative aspect of the study). The sample for the quantitative aspects of this study (i.e., the empirical validation of the identified constructs) was collected as part of the broader restandardisation and represented a stratified random sample of 1026 children between the ages of 3 and 8 years from across the United Kingdom and Eire. Three measures, namely a biographical questionnaire, the GMDS-ER and a construct evaluation form were used to gather the qualitative and quantitative data. The qualitative data was analysed by means of facet analysis and literature control. The quantitative data was analysed by using exploratory common factor analysis using oblique (DQUART) rotation to empirically verify the qualitatively identified construct model by specifying a onefactor solution for each underlying construct.
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Beltz, Morgan. „The Declining Natural Fish Stock: A Proposed Solution to Public Fear and Perceptions of Genetically Modified Fish“. Scholarship @ Claremont, 2013. http://scholarship.claremont.edu/cmc_theses/765.
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The global fish population is declining. Aquaculture production is saturated and the global fish stock is operating at an unsustainable level. Genetically modified (GM) fish is a potential solution to relieve the natural fish stock, if the FDA grants the approval. The global fish population is harmed by environmental conditions and the inability for fish to adapt to changing conditions and human interactions. Genetic modification is a growing technology that has the ability to alleviate the fishing industry by modifying fish to grow faster, be disease tolerant, eat plant-based food, and be more nutritious. However, the approval process has been halted by complications in the approval process and government leaders responding to public fears and concerns of the safety of genetically modified fish. This thesis reviews the background of the fishing industry, concerns over GMOs, and analyzes the politics preventing the approval of GM fish. Lastly, this thesis recommends six approaches the FDA should mandate to reassure the public of the safety of GM fish.
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Nunvář, Rostislav. „Programové prostředky pro simulaci a vizualizaci elektromagnetických struktur“. Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-219141.
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The content of master´s thesis is to introduce with OpenSource software, which use finite element method and to study facilities implementation of free accessible library solvers, meshes and visualization tools. Further there are individual modules introduced. Is chosen suitable combination of OpenSource tools, which create full simulation facility for finite element method. In the conclusion, several electromagnetic examples are solved.
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Bachofner, Gran Clara. „Grundvattenmodellering inom Loddby före detta Sulfitmassabruk“. Thesis, Uppsala universitet, Luft-, vatten och landskapslära, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-382271.
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Loddby sulfitmassabruk var under sin verksamhetstid beläget vid Loddbyviken, cirka fem kilometer norr om Norrköping. På bruket bedrevs tillverkning av sulfitmassa mellan år 1899 och 1977 inom ett område som omfattar 18,6 hektar. Det före detta sulfitmassabruket anses idag vara förorenat till den grad att det medför en mycket stor risk för människors hälsa och miljön, men för att kunna besluta om åtgärder gällande den förorenade marken vid Loddby f.d. sulfitmassabruk behöver bland annat de hydrogeologiska förhållandena inom området klargöras. Detta examensarbete syftade till att kartlägga grundvattenströmningen vid Loddby f.d. sulfitmassabruk genom att utveckla en platsspecifik grundvattenmodell med modellkoden MODFLOW i programvaran Groundwater Modeling System (GMS). Dessutom avsåg examensarbetet att undersöka hur grundvattenströmningen i området påverkas av fluktuationer i den intilliggande Loddbyvikens vattennivå. Initialt utvecklades en konceptuell modell för området, där det hydrologiska systemet förenklat beskrevs med avseende på områdets geologi, hydrologi och klimat. Modellområdet avgränsades utefter topografiska vattendelare samt hydrologiska gränser och delades sedan vertikalt in i tre lager utefter de huvudsakliga jordmaterial som hade identifierats vid undersökningar i området: fyllnadsmaterial, lera och morän. I GMS delades modellområdet sedan in i ett rutnät med storleken 5x5 meter och dess ränder tilldelades lämpliga randvillkor. Genom att interpolera utsträckningen av modellens tre lager från sonderingspunkter med känd geologi kunde den konceptuella modellen beskrivas matematiskt i programvaran. För att öka modellens tillförlitlighet kalibrerades jordmaterialens hydrauliska konduktiviteter mot observerade grundvattennivåer i flertalet grundvattenrör inom Loddby f.d. sulfitmassabruk. Efter kalibrering var fyllnadsmaterialets, lerans samt moränens hydrauliska konduktivitet 2,1ˑ10-4 m/s, 5,7ˑ10-7 m/s respektive 3,9ˑ10-5 m/s. En känslighetsanalys utfördes slutligen för att undersöka hur valet av värden på jordmaterialens hydrauliska konduktiviteter samt grundvattenbildningen påverkar modellresultaten. Simuleringarna med den kalibrerade modellen visade bland annat att grundvattnet generellt rör sig från områdets västra delar mot Pjältån och Loddbyviken i norr och öster, dock runt de områden där bergytan når höga nivåer. Förändringar i Loddbyvikens vattennivå visade sig ha en viss påverkan på mängden vatten i systemet, men bedömdes inte medföra en större effekt på strömningsmönstret i området. Känslighetsanalysen visade att modellen var mycket känslig för värdet på grundvattenbildningen, samt att även den hydrauliska konduktiviteten för moränen hade en stor effekt på resultatet. Ett lågt värde på lerans genomsläpplighet visade sig kunna leda till modelleringssvårigheter och fyllnadsmaterialets konduktivitet hade generellt en liten påverkan på resultatet.Loddby sulphite pulp factory was during its active days located next to Loddbyviken, approximately five kilometers north of Norrköping. Production of sulphite paper pulp was conducted between the years 1899 and 1977 within an area of 18,6 hectares. The former sulphite pulp factory is today considered polluted to the extent that it is entailing a great risk for human health and the environment, but to be able to decide what measures to take, the hydrogeological conditions in the area need to be clarified. The objective of this master’s thesis was to map the groundwater flow pattern within Loddby former sulphite pulp factory by developing a site-specific groundwater model with the groundwater flow model MODFLOW in the software Groundwater Modeling System (GMS). The master’s thesis also aimed at examining how the groundwater movement in the area is affected by fluctuations in the water level of Loddbyviken. A conceptual model was initially created to describe the hydrological system in a simplified way with regards to the geology, hydrology and climate within the area. The model domain was delimited by topographical water divides and hydrological boundaries, and was thereafter divided into three horizontal layers based on the main materials that have been identified during investigations within the area: filling material, clay and till. In GMS, the model domain was divided into a 5x5 meter grid and its borders were assigned appropriate boundary conditions. By interpolating the three model layers from scatter point data of known geology, the conceptual model could be described mathematically within the software. To increase the reliability of the model, the hydraulic conductivities of the materials were then calibrated against observed hydraulic head in several groundwater monitoring wells in the area. After the calibration, the hydraulic conductivities of the filling material, clay and till were 2,1ˑ10-4 m/s, 5,7ˑ10-7 m/s and 3,9ˑ10-5 m/s respectively. A sensitivity analysis was then performed in order to examine how the values of hydraulic conductivity and groundwater recharge would affect the model results. Simulations with the calibrated model showed that the groundwater generally moves from the western parts of the area towards Pjältån and Loddbyviken in the north and east. However, it moves around the areas where the impermeable bedrock is close to the ground surface. Changes in the water level of Loddbyviken proved to have some effect on the amount of water in the system, but they did not entail a greater influence on the groundwater movement pathways in the area. The sensitivity analysis showed that the model was very sensitive regarding the groundwater recharge and the hydraulic conductivity for the till. A very low conductivity of clay turned out to lead to some modeling difficulties and the conductivity of the filling material showed to only have a small effect on the result.
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Grami, Said. „Identification non linéaire du modèle de frottement GMS pour l'amélioration de la commande des systèmes mécaniques“. Mémoire, École de technologie supérieure, 2009. http://espace.etsmtl.ca/51/1/GRAMI_Said.pdf.
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Le frottement est un phénomène physique qui se manifeste au niveau des surfaces de contact
en mouvement relatif. Il présente un risque accablant dans la dégradation des systèmes de
commande en introduisant des erreurs de suivi, des cycles limites et carrément des instabilités.
Afin de compenser les effets du frottement en temps réel, le but de cette thèse est de proposer
une approche d'identification en ligne du modèle de frottement GMS. Pour ce faire, nous
proposons en premier lieu, une nouvelle approche d'identification de la partie statique du frottement
(frottement de Stribeck) basée sur une théorie non linéaire d'optimisation min-max. Cette
approche permet d'identifier tous les paramètres du modèle de Stribeck en même temps et en
particulier les paramètres qui agissent d'une façon non linéaire dans le modèle de frottement.
L'extension pour le modèle de GMS n'est pas faisable parce que le modèle GMS ne vérifie
pas les conditions d'application de cette théorie. Ainsi, une nouvelle approche est présentée
pour identifier les paramètres du modèle GMS. Cette approche est basée sur la mesure de la
force de frottement et une linéarisation du modèle GMS par rapport aux paramètres inconnus.
L'observateur robuste de Marino est ensuite utilisé pour estimer les paramètres inconnus du
modèle malgré les perturbations introduites par les erteurs d'approximation. Pour implanter
l'observateur, une approche de filtrage est proposée pour éliminer les discontinuités des signaux.
Un filtre particulier est introduit pour tenir compte de la commutation des signaux lors
de la transition entre le régime de préglissement et le régime de glissement.
Une extension de la méthode qui, cette fois, n'est pas fondée sur l'hypothèse de la mesure de la
force de frottement est proposée. Pour ce faire, une méthode de calcul de la force de frottement
filtrée à partir des signaux de vitesse et de commande est développée . Une méthode de filtrage
avec des conditions initiales appropriées est proposée pour vérifier les conditions d'application
de l'observateur. Une validation expérimentale de l'approche d'identification est présentée à la
fin de la thèse. Les résultats montrent que l'approche d'identification du modèle de frottement
GMS proposée dans cette thèse admet de très bonnes performances.
À la fin, des recommandations sont formulées relativement à i) une étude approfondie de la
fonction de commutation qui assure la transition entre les deux régimes de frottement pour un
modèle à plusieurs étages et ii) une meilleure caractérisation de la fonction de transfert du banc
expérimental afin de valider de façon plus juste l'approche proposée sur le plan pratique.
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Ribeiro, Elton Cândido. „Kant e o fundamento da moralidade: um estudo da dedução do imperativo categórico em GMS III“. Pontifícia Universidade Católica de São Paulo, 2016. https://tede2.pucsp.br/handle/handle/18785.
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Conselho Nacional de Desenvolvimento Científico e Tecnológico
This work aims to study the deduction of the categorical imperative in the third section of Kant’s Groundwork for the Metaphysics of Morals. Undoubtedly, this deduction is an important Kantian attempt to offer a foundation for his a priori ethics. More than two centuries later, there is no consensus among scholars and commentators regarding what is the structure of the argument, as well as its aim and its importance in the Kantian Critical Philosophy. This thesis is structured in three chapters. The first chapter studies the analysis of the concept of “good will” in the first section of Groundwork. The second chapter follow the analysis of the concept of “finite rational agent” in the second section. Lastly, the third chapter studies the deduction of the categorical imperative in the third section of Groundwork. The argument of the deduction is comprised in the following steps: the analytical relationship between liberty and morality; the presupposition of the effectiveness of the liberty of all rational being; the presupposition of the effectiveness of the liberty of the rational-sensitive being; the deduction of the categorical imperative
Este trabalho tem como objetivo estudar a dedução do imperativo categórico na terceira seção da Fundamentação da Metafísica dos Costumes, de Immanuel Kant. Sem dúvida, esta dedução é uma importante tentativa do filósofo de oferecer uma fundamentação para sua ética a priori. Mais de dois séculos depois, ainda não há consenso entre os estudiosos e comentadores sobre a estrutura do argumento, seu objetivo e sua importância na filosofia crítica kantiana. Para lidar com a questão, esta dissertação é estruturada em três capítulos. O primeiro capítulo estuda a análise do conceito de "boa vontade" empreendida na primeira seção da Fundamentação. O segundo capítulo segue a análise do conceito de "agente racional finito", na segunda seção. Finalmente, o terceiro capítulo estuda a dedução do imperativo categórico na terceira seção da Fundamentação. O argumento da dedução é compreendido nos seguintes passos: a relação analítica entre liberdade e moralidade; a pressuposição da efetividade da liberdade de todos os seres racionais; a pressuposição da efetividade da liberdade do ser racional-sensível; a dedução do imperativo categórico
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Xie, Pingping. „Studies on the Development and Application of the Rainfall Estimation Method Using GMS Infrared Imagery Data“. 京都大学 (Kyoto University), 1992. http://hdl.handle.net/2433/168822.
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本文データは平成22年度国立国会図書館の学位論文(博士)のデジタル化実施により作成された画像ファイルを基にpdf変換したものであるKyoto University (京都大学)
0048
新制・課程博士
博士(理学)
甲第4976号
理博第1373号
新制||理||766(附属図書館)
UT51-92-J23
京都大学大学院理学研究科地球物理学専攻
(主査)教授 光田 寧, 教授 廣田 勇, 教授 村松 久史
学位規則第4条第1項該当
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1994. https://ul.qucosa.de/id/qucosa%3A12694.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1996. https://ul.qucosa.de/id/qucosa%3A12698.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1997. https://ul.qucosa.de/id/qucosa%3A12700.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1999. https://ul.qucosa.de/id/qucosa%3A12701.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 2000. https://ul.qucosa.de/id/qucosa%3A12705.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 2003. https://ul.qucosa.de/id/qucosa%3A12708.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Elsevier, Urban & Fischer, 2004. https://ul.qucosa.de/id/qucosa%3A12725.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1995. https://ul.qucosa.de/id/qucosa%3A11661.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1993. https://ul.qucosa.de/id/qucosa%3A12689.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 2002. https://ul.qucosa.de/id/qucosa%3A12707.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 1998. https://ul.qucosa.de/id/qucosa%3A12720.
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Deutsche, Gesellschaft für Medizinische Informatik Biometrie und Epidemiologie. „Informatik, Biometrie und Epidemiologie in Medizin und Biologie: offizielles Organ der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (GMDS) e.V“. Urban & Fischer, 2001. https://ul.qucosa.de/id/qucosa%3A12737.
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Silva, Huederson Aparecido Botura da. „Utiliza??o da frequ?ncia de 915 MHz para monitoramento e supervis?o de isoladores polim?ricos classe de tens?o de 500 kv“. Pontif?cia Universidade Cat?lica de Campinas, 2012. http://tede.bibliotecadigital.puc-campinas.edu.br:8080/jspui/handle/tede/537.
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Previous issue date: 2012-12-07In an eletric power transmission system, the insulators are directly associated with the security level of the web, which your fail influence on companies statistics. The polymeric insulators are become more utilized year after year, having numerous advantages to its competitors (glass and/ or porcelain), however, its useful life can not be determined yet. This paper discuss the use of the free frequency of 915 MHz for monitoring and supervision af this polymeric insulators, and can thus provide data about the web, as well, indicate its useful live. Was performed a data transmission with variations of the intensity of eletric fields resulting from the line fitting of the 500kv rated voltage insulator. The variation of the electric field was obtained using different anti-corona rings. Its values were obtained using software as Gmsh and GetDP which use the method of finites elements. Was possible to observe that the central frequency of the carrier didi not change when a sign passed throw the electric field, besides being possible to perform the communication between the sensors having, at the most critical configuration, a packet loss equal to 1,6%. Also was possible observerd that for all tests performed occurred a small degradation of the sign during the data transmission.
Em um sistema de transmiss?o de energia el?trica, os isoladores est?o diretamente associados ao n?vel de seguran?a da rede, na qual sua falha influ?ncia em indicadores das concession?rias. Os isoladores polim?ricos est?o adquirindo com o passar dos anos maior utiliza??o, sendo que possui in?meras vantagens perante seus concorrentes (vidro e/ou porcelana), entretanto sua vida ?til ainda n?o pode ser determinada. Este trabalho aborda a utiliza??o da frequ?ncia livre de 915 MHz para monitoramento e supervis?o destes isoladores polim?ricos, sendo poss?vel assim fornecer dados sobre a rede bem como indicando a sua vida ?til. Foi realizado uma transmiss?o de dados mediante varia??es da intensidade do campo el?trico decorrentes do terminal fase do isolador da classe de tens?o de 500 kv. A varia??o da intensidade do campo el?trico foi obtido utilizando an?is anti-corona diferentes, sendo seus valores obtidos atrav?s de simula??es utilizando os softwares Gmsh e GetDP que utiliza o m?todo dos elementos finitos. Foi poss?vel observar que a frequ?ncia central da portadora n?o teve varia??o quando o sinal passava pelo campo el?trico, al?m de ser poss?vel realizar a comunica??o entre os n?s sensores tendo, na configura??o mais cr?tica, uma perda de pacotes igual a 1,6%. Tamb?m foi poss?vel observar que para todos os ensaios realizados ocorreu pequena degrada??o do sinal durante a transmiss?o de dados.
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Jeon, Suekyoung [Verfasser], Stefan [Akademischer Betreuer] Eimer, Andreas [Akademischer Betreuer] Wodarz und Ralf [Akademischer Betreuer] Heinrich. „Analyzing UNC-50/GMH1 dependent membrane trafficking in yeast and C. elegans / Suekyoung Jeon. Betreuer: Stefan Eimer. Gutachter: Andreas Wodarz ; Ralf Heinrich“. Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1079717927/34.
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Povey, Jenny-Louise. „Exploring the construct-related validity of the eye and hand coordination subscale of the Griffiths Mental Development Scales-Extended revised (GMDS-ER)“. Thesis, Nelson Mandela Metropolitan University, 2008. http://hdl.handle.net/10948/661.
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To constantly add to our understanding of child development, a valid, comprehensive, well-researched measure is needed. The recent revision and standardisation of the Griffiths Mental Development Scales - Extended Revised (GMDS-ER) has necessitated investigations into its psychometric properties. This measure is used to identify developmental delays in children and critical decisions may be made, hence it is imperative that this measure be deemed both reliable and valid. This study aimed to contribute to the broader restandardisation project and focussed on gathering qualitative and quantitative construct-related validity evidence for one of the six Subscales of the GMDS-ER, namely the Eye and Hand Coordination Subscale (Subscale D). An exploratory descriptive method using a triangulation approach was used to explore the construct-related validity evidence of the Eye and Hand Coordination Subscale. A non-random purposively selected sample of 6 experts, who had worked at least 10 years with children assessing and evaluating the domain of eye-hand coordination, participated in a facet analysis to identify the underlying dimensions tapped by the Eye and Hand Coordination Subscale. The sample for the quantitative aspects of this study, the empirical validation of the construct model, was collected as part of the broader restandardisation and represented a stratified sample of 1026 children between the ages 24 months and 96 months from across the United Kingdom and Eire. Three measures, namely a biographical questionnaire, the GMDS-ER and a construct evaluation form were used to gather the qualitative and quantitative data. The qualitative data was analysed by means of a facet analysis and literature control which included examining other tests or subtests that tapped eye-hand coordination skills. The quantitative data was analysed by means of exploratory common factor analysis using oblique (DQUART) rotation in order to verify the qualitatively identified construct model by specifying a one-factor solution for each underlying construct. While literature suggests that eye-hand coordination is multidimensional in nature the facet analysis revealed that the tasks tapped by Subscale D were not tapping complex skills aside from eye-hand coordination. The facet analysis thus revealed that all the items tap the eye-hand coordination of fine motor tasks and that these items could be grouped into two categories, using writing utensils and object manipulation. The results from the factor analysis confirmed that the items on Subscale D have one underlying construct and further exploration confirmed that these items could in fact be grouped into two categories. The coefficients of congruence for SES and gender were satisfactory and thus the construct model was validated across these groups as well. The study has provided extensive qualitative and quantitative evidence for the construct-related validity of the Eye and Hand Coordination Subscale of the GMDS-ER, thus validating its use as a sound measure of eye-hand coordination development in children aged 2 to 8 years. The content coverage however, seemed to indicate that the tasks required do not adequately cover all the facets of eye-hand coordination and some of these item types are tapped by the other Subscales in the measure. Hence, should the Subscale be used as an independent assessment of eye-hand coordination, the eye-hand coordination development of the child would have a narrow focus. In addition, in reviewing the variety of tasks in the two sections for the older and younger child, the researcher noted that while section III tapped a variety of skills, section IV only focused on skills associated with drawing, copying and writing. A review of the age appropriateness of the items and the item analysis results from the revision seemed to indicate that some of the items assessing the older child may need to be revised. Further, the researcher suggested that the revision should consider adding additional dimensions to the tasks assessed. Overall, it is the researcher‟s opinion that this Subscale was not given adequate attention during the revision process and should future revisions occur, the recommendations from this study should be considered.
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Sefton, Martin. „Ständiga förbättringar och praktisk problemlösning : en explorativ studie på Saab Automobile AB“. Thesis, University West, Department of Engineering Science, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hv:diva-1638.
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Continuous improvement is one of five principles in General Motors – Global Manufacturing System (GM-GMS). GM-GMS has been used by Saab Automobile AB since 2003 and is a central component for realisation of GM’s vision. Internal audits have discovered problems with one of the tools, practical problem solving (PPS), which needs to be improved. The department manufacturing of press and body (PK) wants to survey the problems and initiate a process of improvement. The purpose of this thesis work is to develop a foundation for future re-designs of the PPS process. Employees have been interviewed and observed in order to explore possible difference theoretical and practical problem solving with PPS. The result of the investigation shows 4 different and interrelated problem categories. 1. Information transfer, PPS hand over to product quality engineers (PQE) department cause problem when general assemblies (GA) are excluded from the improvement work. General assemblies do not get any feedback information from (PQE) about planed countermeasures. 2. Problem solving, team leaders has difficulties with identifying the true problem. Using “five-why” during the analysis work causes problem, since team leaders do not have the knowledge of how to use the tool in a proper way. 3. Documentation of PPS, the content in the PPS-form is a problem according to team leaders. Lack of knowledge and understanding of how to use the PPS-document leads to incomplete and incorrect analysis. 4. Coordination of involved people, support and help are missing from the management and quality engineer according team leaders. PPS from Global Costumer Audit are imposing time stress according to team leaders. Recommendations for further work is to investigate the opportunities with a web based PPS and process to improve information transfer and documentation of PPS. A second recommendation is to train and coach team leaders in problem solving and improve coordination of involved people and skills in problem solving.
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Young, Stefan J. „Groundwater Model Studying Effects of Existing Recharge Basin and Proposed Subsurface Barrier for a Ranch in Santa Rosa Creek Watershed“. DigitalCommons@CalPoly, 2021. https://digitalcommons.calpoly.edu/theses/2294.
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A groundwater model of a 126.2-acre ranch in Cambria, California was expanded upon to analyze the effects of artificial recharge and a subsurface barrier. The ranch lies within the 48mi2 Santa Rosa Creek Watershed along the Central Coast of California. The mainly agricultural watershed outfalls to the Pacific Ocean to its west. Creek Lands Conservation, a non-profit that aims to conserve and restore habitat along the Central Coast, plans to identify projects to restore stream flow during dry seasons in the creek that runs through the Santa Rosa Creek Watershed and to increase artificial groundwater recharge. This study focuses on two of those projects. One project is an existing recharge basin and the other is a subsurface barrier. The objective of this numerical model is to improve upon an existing model by using a longer duration of data to calibrate the model, calibrating the model to hydraulic properties of soil samples that were obtained from the site at various depths, refining elevations of layers through integration of new borehole exploration data, and adding updated and new data such as mountain front recharge and pumping rates. The modeling program used was GMS which allows calculation and determination of heads and flow directions. Within the model, there are three separate layers based on hydrogeological characterization from previous studies. There is an upper unconfined zone, a confining clay layer, and a confined zone. A package within GMS (Groundwater Modeling System) called PEST (i.e., Parameter ESTimation) was used to calibrate the model to known water surface elevations throughout the site. Data such as elevations, head boundaries, stream flow, pumping rates, recharge, evapotranspiration, well locations, and hydraulic properties of the subsurface was processed and incorporated into the overall model in GMS. Recharge rates from the basin were estimated to be 0.1 m/day roughly starting in February and ending in May for each year. The model showed that the confining layer slows down the flow of water from the recharge basin, but it does eventually percolate into the underlying groundwater aquifer before reaching Santa Rosa Creek after a time period of 5 years. The proposed subsurface barrier does reduce travel times of groundwater by roughly a year and helps percolation of water into the confined layer. With the subsurface barrier it was seen that the water held within the confined aquifer increased on average 5,200 m3 each year.
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Corack, Edward J. „Impact of Phytoremediation System on Groundwater Flow in a Shallow Aquifer System“. Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/42183.
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There are many methods for cleaning up contaminated soil and groundwater. Phytoremediation is an engineered method that utilizes plants and trees to remove or immobilize inorganic and organic contaminants. The plants and trees can contain contaminant plumes, uptake the contaminants, or aid in the degradation of the
contaminants through several poorly understood mechanisms.
Hybrid poplar trees were planted to contain a creosote contaminant plume at the study-site in Oneida, Tennessee. This research looks at how the trees will affect groundwater flow in the site. This is accomplished with the groundwater modeling program MODFLOW. The trees are simulated using the Evapotranspiration Package within MODFLOW, within the GMS modeling platform, to produce a two-dimensional unconfined aquifer viewpoint groundwater model.
Site characterization, setup, and rationale are provided. The modeling methodology including calibration, sensitivity analysis, non-unique solution check, and verification are also provided. The modeling methodology included steady-state model calibration at the study-site to match observed field data; precursory steady-state and subsequent practice transient calibrations at the site; and incorporation of the simulation of evapotranspiration in the final transient model calibrations at the site.
The results show that a phytoremediation system consisting of densely-planted hybrid poplar trees can indeed impact groundwater flow, although not to the extent that clearly would contain a creosote contaminant plume. Various input parameters including specific yield, transient recharge, starting heads, evapotranspiration rates, and evapotranspiration extinction depths impacted MODFLOW model sensitivity in transient calibrations. Varying the time steps in post-precipitation stress periods did not significantly impact the model output. The interception trench conductance played a minimal role in the calibration, but trench groundwater collection data was lacking, and the trench was frequently in need of maintenance. Further suggested data requirements include more frequently collected rainfall and piezometer data, as well as the installation of more piezometers outside the model domain contained in this study.
Using the Evapotranspiration Package in MODFLOW provided more realistic and authentic results than using the Well Package (used in a previous study of the site by Panhorst in 2000) to simulate evapotranspiration. The Evapotranspiration Package in MODFLOW incorporates transpiration extinction depths that prevent transpiration when the water table drops below a certain depth. Further suggested program development includes incorporating an asymptotic function for transpiration rates and allowing the Evapotranspiration Package to import evapotranspiration rates, extinction depths, and elevations. It may be deduced from this impact of flow that the tree system will aid in containment of a contaminant plume, but at the trees current growth stage, and with the coal layer present at the site, the containment is limited.Master of Science
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Barnes, Peter J., Audra K. Hernandez, Stefan N. O’Dougherty, III William J. Schap und Erik Muller. „THE GALACTIC CENSUS OF HIGH- AND MEDIUM-MASS PROTOSTARS. III. 12 CO MAPS AND PHYSICAL PROPERTIES OF DENSE CLUMP ENVELOPES AND THEIR EMBEDDING GMCs“. IOP PUBLISHING LTD, 2016. http://hdl.handle.net/10150/622167.
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We report the second complete molecular line data release from the Census of High-and Medium-mass Protostars (CHaMP), a large-scale, unbiased, uniform mapping survey at sub-parsec resolution, of millimeter-wave line emission from 303 massive, dense molecular clumps in the Milky Way. This release is for all (CO)-C-12 J = 1 -> 0 emission associated with the dense gas, the first from Phase II of the survey, which includes (CO)-C-12, (CO)-C-13, and (CO)-O-18. The observed clump emission traced by both (CO)-C-12 and HCO+ (from Phase I) shows very similar morphology, indicating that, for dense molecular clouds and complexes of all sizes, parsec-scale clumps contain. similar to 75% of the mass, while only 25% of the mass lies in extended (>10 pc) or "low density" components in these same areas. The mass fraction of all gas above a density of 10(9) m(-3) is xi(9) greater than or similar to 50%. This suggests that parsec-scale clumps may be the basic building blocks of the molecular interstellar medium, rather than the standard GMC concept. Using (CO)-C-12 emission, we derive physical properties of these clumps in their entirety, and compare them to properties from HCO+, tracing their denser interiors. We compare the standard X-factor converting I (CO)-C-12 to N-H2 with alternative conversions, and show that only the latter give whole-clump properties that are physically consistent with those of their interiors. We infer that the clump population is systematically closer to virial equilibrium than when considering only their interiors, with perhaps half being long-lived (10s of Myr), pressure-confined entities that only terminally engage in vigorous massive star formation, supporting other evidence along these lines that was previously published.
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Adeniyi, Oluwafunmilola Foluke. „Access to safe food in South Africa as a human rights imperative“. Thesis, University of the Western Cape, 2015. http://hdl.handle.net/11394/4930.
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Magister Legum - LLMThe aim of this study is to examine laws and policies relating to food safety in South Africa, specifically with regard to labelling requirements in the food industry. It is hoped that this research will serve as a pointer for policy and legislative reforms in a bid to identify weak areas as well as encourage accountability and strengthen government’s response to the realisation of the right to safe food as a human right imperative.
National Research Foundation (NRF)
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Gunnarsson, Erik, und Sten-Yngve Södergren. „Minnesteknik – ett användbart verktyg vid inlärning?“ Thesis, Malmö högskola, Fakulteten för lärande och samhälle (LS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-29621.
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För att tillgodogöra sig fakta och omvandla den till kunskap så är det viktigt att vi kan minnas och komma ihåg det vi ser och hör. Precis som vi behöver bra program i vår dator för att hantera informationen, så kan vi få hjälp av minnesstrategier för att lättare kunna placera och plocka fram minnen.Arbetets syfte och frågeställning har varit att belysa tillämplighet och användande av minnesteknik och minnesträning som undervisnings- och inlärningsverktyg inom allmänpedagogisk undervisning, samt även se på dess möjligheter och begränsningar.Underlaget till den teoretiska bakgrunden har framförallt inhämtats från tidigare forskning, studier, och annan för ämnet relevant litteratur.Arbetets metod är induktiv och förhållningssättet hermeneutiskt då målet varit att skapa förståelse. Vidare har arbetet ett kvalitativt angreppssätt baserad på observationer av företeelser och data och till sin undersökningsform deskriptiv då avsikten varit att belysa och beskriva tillämplighet och användande av minnesteknik.Resultaten visade att forskningsfältet kring minnesträning var i viss mån motsägelsefullt och spretigt, vissa studier visade på effekter, medan andra helt förkastade samma teori. Likaså kunde vi se att en del forskning tenderar att vara självrefererande och partisk och inte alltid samstämmig. Vidare pekade resultatet på att det inte fanns någon entydigt bild om fördelarna och effekter av minnesträning. Arbetet visade också på att det finns såväl möjligheter som begränsningar med olika former av minnesteknik. Arbetet kunde också påvisa ett antal goda exempel där lärare och skolor med stor framgång och goda resultat bedrivit minnesträning som naturliga inslag i undervisningen.I slutsatsen kunde vi konstatera att det fanns ett stort behov av fristående och objektiv forskning kring minnesträning och dess effekter i allmänhet. Vi såg också ett stort forskningsbehov kring icke datorbaserad minnesträning och likaså ett behov av forskning med fokus på allmänpedagogik. Vi har också kunnat se att minnesträning ger effekter på bland annat arbetsminnet, och att det är viktigt att vara engagerad som lärare.