Thematische Bibliographien / Ghh

Auswahl der wissenschaftlichen Literatur zum Thema „Ghh“

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Veröffentlicht am 25. Juli 2024

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Zeitschriftenartikel zum Thema "Ghh"

1

Ratnasari, Agnes, Efri Efri, Muhammad Syamsoel Hadi und Hasriadi Mat Akin. „KETAHANAN BEBERAPA GENOTIPE SORGUM (Sorghum bicolor [L]Moench) TERHADAP PENYAKIT ANTRAKNOSA (Colletotrichum graminicola) PADA DUA SISTEM POLA TANAM BERBEDA“. Jurnal Agrotek Tropika 7, Nr. 2 (03.05.2019): 351. http://dx.doi.org/10.23960/jat.v7i2.3258.

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Tujuan penelitian ini yaitu mengetahui ketahanan 15 genotipe sorgum yang ditanam pada dua sistem tanam berbeda yaitu monokultur dan tumpangsari. Penelitian ini dilaksanakan pada bulan April 2017- Februari 2018 di Desa Sukanegara, Kecamatan Tanjung Bintang, Kabupaten Lampung Selatan, Lampung dan di Laboratorium Hama dan Penyakit Tanaman Fakultas Pertanian Universitas Lampung. Perlakuan disusunmenggunakan rancangan acak kekompok dalam Split Plot Design dengan faktor utama adalah sistem pola tanam (tumpangsari, monokultur), dan anak petak adalah 15 genotipe sorgum (Numbu, Samurai 1, GH3, UPCA, GH4, P/I WHP, GH6, Super 2, GH13, P/F 51-93-C, Super 1, GH5, Mandau, GH7 dan TalagaBodas). Monokultur sorgum ditanam pada jarak 80 cm x 20 cm. Tumpangsari sorgum ubikayu dilakukan dengan cara menanam sorgum di antara tanaman ubikayusehingga jarak tanam sorgum tetap 80 cm x 20 cm, sedangkan jarak tanam ubikayu 80 cm x 60 cm, baik sorgum maupun ubikayu ditanam secara bersamaan. Hasil penelitian menunjukkan bahwa sistem tanam tumpangsari lebih efektif untuk menekan intensitas penyakit antraknosa. Pada penelitian ini intensitas penyakit antraknosa terhadap 15 genotipe sorgum yang diamati dikelompokan menjadi 3 kategori yaitu tinggi, sedang dan rendah. Genotipe Numbu, GH3, Talaga Bodas, Super 1, dan Mandau adalah genotipe dengan intensitas penyaki terendah dibandingkan genotipe Samurai 1, UPCA, GH4, P/I WHP, GH13, P/F 5-193-C, GH5, GH6 dan GH7 . Genotipe Samurai 1, UPCA, GH4, P/I WHP, GH13, P/F 5-193-C, GH5, GH6 dan GH7 adalah genotipe yang intensitas penyakitnya lebih rendah dibandingkan genotipe Super 2. Dan genotipe Super 2 adalah genotipe dengan intnsitas penyakit antraknosa tertinggi.
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2

Nguyễn Quốc Sửu. „Nền công vụ ưu tú và điều kiện bảo đảm cho nền công vụ ưu tú ở Việt Nam“. Quản lý nhà nước, Nr. 340 (21.05.2024): 28–35. http://dx.doi.org/10.59394/qlnn.340.2024.844.

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3

Winkelman, D. C., und R. B. Hodgetts. „RFLPs for somatotropic genes identify quantitative trait loci for growth in mice.“ Genetics 131, Nr. 4 (01.08.1992): 929–37. http://dx.doi.org/10.1093/genetics/131.4.929.

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Abstract Restriction fragment length polymorphisms for somatotropic genes were tested for associations with body weight and postweaning growth rate in mice. Polymorphisms for growth hormone (GH) and insulin-like growth factor 2 (IGF-2) genes were identified in stock population lines which had been subjected to long-term selection for high 42-day body weight (H lines) or randomly mated (FP and C lines). Two F2 populations of mice (5F2 and MF2) were generated from crosses between a single H line of mice and two unselected control lines and subsequently, two divergently weight selected sublines were generated from each F2 population. The GHh allele which had originally been fixed in three of four H lines and absent from all FP and C lines was found to have a significant (P less than 0.01) effect on 42-day weight and postweaning growth rate in the F2 populations. However, GHh was associated with lower 42-day weight in the F2 populations, suggesting that the positive association between GHh and weight in the stock population was unique to the high weight selected genetic background of those lines. In agreement with this, the frequency of GHh increased in sublines selected for high 42-day weight and decreased in sublines selected for low 42-day weight. The IGF-2H5 allele was associated with higher weights in a sex-dependent manner in 5F2. In the high selected subline derived from 5F2, a significant increase in the frequency of IGF-2H5 was observed. Therefore this allele, in contrast to GHh, appears to be a positive indicator of growth irrespective of genetic background.
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Chen, Jiaxuan, Yuanju Yuan, Fangfang Xie, Zhike Zhang, Jianye Chen, Rong Zhang, Jietang Zhao, Guibing Hu und Yonghua Qin. „Metabolic Profiling of Organic Acids Reveals the Involvement of HuIPMS2 in Citramalic Acid Synthesis in Pitaya“. Horticulturae 8, Nr. 2 (16.02.2022): 167. http://dx.doi.org/10.3390/horticulturae8020167.

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Pitayas are rich in organic acids, especially citramalic acid, which is significantly higher than the plants. However, the mechanism of citramalic acid biosynthesis remains to be fully elucidated. In this study, organic acid compositions and contents, as well as expression patterns of key genes related to organic acid metabolism were analyzed during fruit maturation of four different pitaya cultivars i.e., ‘Guanhuabai’ (GHB), ‘Guanhuahong’ (GHH), ‘Wucihuanglong’ (WCHL), and ‘Youcihuanglong’ (YCHL). The total organic acid contents increased first and then declined during fruit maturation. The main organic acids were citramalic acid during the early stages of GHB, GHH, and WCHL pitayas, and dominated by malic acid as fruit maturation. In comparison, citric acid and malic acid were main organic acid for ‘YCHL’ pitaya. Citramalate synthase (IPMS) was involved in the synthesis of citramalic acid, and three types of HuIPMS i.e., HuIPMS1, HuIPMS2, and HuIPMS3, were obtained in our study. Highest expression levels of HuIPMS1 were detected in sepals, while HuIPMS2 and HuIPMS3 exhibited preferential expression in tender stems and ovaries. The expression levels of HuIPMS2 and HuIPMS3 were positively correlated with the content of citramalic acid in the four pitaya cultivars. HuIPMS2 was a chloroplast-localized protein, while HuIPMS3 presented a cytoplasmic-like and nuclear subcellular localization. These findings provide an important basis for further understanding of the molecular mechanism that leads to citramalic acid metabolism during pitaya fruit maturation.
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Phuoc, Le Huu, Irfan Suliansyah, Feri Arlius, Irawati Chaniago, Nguyen Thi Thanh Xuan und Pham Van Quan. „Responses of Growth and Grain Yield of IR50404 Rice to Temperature Stress“. International Journal of Agricultural Sciences 6, Nr. 1 (04.06.2022): 9. http://dx.doi.org/10.25077/ijasc.6.1.9-18.2022.

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Climate changes, rising warmth, drought, and CO2, are now seriously influencing agriculture. In this study, four separate greenhouses (labeled GH1, GH2, GH3, and GH4) were built with plastic roofs and walls, except GH1, which had three walls with mesh to evaluate the impact of temperature stress on growth, biomass, and yield of rice variety IR50404 under different temperature regimes. The control treatment group was grown ambient, next to these greenhouses. GH1, GH2, GH3, and GH4’s temperatures were from 0.9 oC to 3.1 oC higher than the ambient (as control). Carbon dioxide concentrations in GH2, GH3, and GH4 were recorded higher than the ambient, from 34.1 ppm to 48.2 ppm. Total vegetative dry matter was reduced from 15.9% to 20.5%, while grain yield declined from 20.8% to 24.6% when the mean temperature increased from 2.9 oC to 3.1 oC. High temperature or a combination of high-temperature stress with elevated CO2 concentration reduced the grain yield and total vegetative dry matter.
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Xu, Changqing, Jiahao Ning, Yi Liu, Mintao Luo, Dongdong Chen, Xiaoling Lin und Yintang Yang. „Optimization Strategy of Regular NoC Mapping Using Genetic-Based Hyper-Heuristic Algorithm“. Symmetry 14, Nr. 8 (09.08.2022): 1637. http://dx.doi.org/10.3390/sym14081637.

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Mapping optimization of network-on-chips (NoCs) for specific applications has become one of the most important keys of the SoC top-level design. However, the topology of NoC applied is usually regular topology, such as mesh, torus, etc., which may generate a large number of isomorphic solutions during the process of NoC mapping, which may reduce the convergence speed of mapping algorithms. In this paper, we proposed a generic-based hyper-heuristic algorithm named IRC-GHH for NoC mapping. To reduce the influence of isomorphic solutions, we analyzed the symmetry of NoC topology and proposed crossover operators based on the isomorphic solution to optimize the algorithm. We studied the situation of invalid crossovers and eliminated invalid iterations by adopting an isomorphic replacement crossover (IRC) strategy. To prevent the algorithm from falling into evolutionary stagnation in the late iteration, we introduce an adaptive mechanism to increase the usage frequency of the IRC operator automatically. Compared with GHH without IRC, the GHH with IRC can achieve, on average 15.25% communication energy reduction and 7.84% communication delay reduction.
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7

Bautista-Cruz, Angélica, Teodulfo Aquino-Bolaños, Jessie Hernández-Canseco und Evangelina Esmeralda Quiñones-Aguilar. „Cellulolytic Aerobic Bacteria Isolated from Agricultural and Forest Soils: An Overview“. Biology 13, Nr. 2 (05.02.2024): 102. http://dx.doi.org/10.3390/biology13020102.

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This review provides insights into cellulolytic bacteria present in global forest and agricultural soils over a period of 11 years. It delves into the study of soil-dwelling cellulolytic bacteria and the enzymes they produce, cellulases, which are crucial in both soil formation and the carbon cycle. Forests and agricultural activities are significant contributors to the production of lignocellulosic biomass. Forest ecosystems, which are key carbon sinks, contain 20–30% cellulose in their leaf litter. Concurrently, the agricultural sector generates approximately 998 million tons of lignocellulosic waste annually. Predominant genera include Bacillus, Pseudomonas, Stenotrophomonas, and Streptomyces in forests and Bacillus, Streptomyces, Pseudomonas, and Arthrobacter in agricultural soils. Selection of cellulolytic bacteria is based on their hydrolysis ability, using artificial cellulose media and dyes like Congo red or iodine for detection. Some studies also measure cellulolytic activity in vitro. Notably, bacterial cellulose hydrolysis capability may not align with their cellulolytic enzyme production. Enzymes such as GH1, GH3, GH5, GH6, GH8, GH9, GH10, GH12, GH26, GH44, GH45, GH48, GH51, GH74, GH124, and GH148 are crucial, particularly GH48 for crystalline cellulose degradation. Conversely, bacteria with GH5 and GH9 often fail to degrade crystalline cellulose. Accurate identification of cellulolytic bacteria necessitates comprehensive genomic analysis, supplemented by additional proteomic and transcriptomic techniques. Cellulases, known for degrading cellulose, are also significant in healthcare, food, textiles, bio-washing, bleaching, paper production, ink removal, and biotechnology, emphasizing the importance of discovering novel cellulolytic strains in soil.
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Tao, Yong, Ruochao Zhao, Jun Shi, De Zhou und Yanqun Han. „In-Plane Elastic Properties of 3D-Printed Graded Hierarchical Hexagonal Honeycombs“. Polymers 16, Nr. 6 (21.03.2024): 859. http://dx.doi.org/10.3390/polym16060859.

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In this study, the graded hierarchical hexagonal honeycomb (GHHH) integrating gradient design and hierarchical design was fabricated using the 3D-printing technique, and its in-plane elastic properties were investigated theoretically, experimentally, and numerically. Theoretical solutions were developed based on the Euler beam theory to predict the effective elastic modulus and Poisson’s ratio of GHHH, and theoretical values were in good agreement with the experimental and numerical results. The effect of gradient design and hierarchical design on the in-plane elastic properties of GHHH was also analyzed and compared. Results showed that the hierarchical design has a more significant effect on Poisson’s ratio and adjusting the internal forces of GHHH compared with the gradient design. In addition, it was found that GHHH exhibited higher stiffness compared with regular hexagonal honeycomb (RHH), graded hexagonal honeycomb (GHH), and vertex-based hierarchical hexagonal honeycomb (VHHH) under the constraint of the same relative density, respectively. Specifically, the effective elastic modulus of GHHH can be enhanced by 119.82% compared to that of RHH. This research will help to reveal the effect of integrating hierarchical design and gradient design on the in-plane elastic properties of honeycombs.
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Le Page, PA, R. Furtado, M. Hayward, S. Law, A. Tan, SJ Vivian, H. Van der Wall und GL Falk. „Durability of giant hiatus hernia repair in 455 patients over 20 years“. Annals of The Royal College of Surgeons of England 97, Nr. 3 (April 2015): 188–93. http://dx.doi.org/10.1308/003588414x14055925060839.

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IntroductionThe surgical management of symptomatic giant hiatus hernia (GHH) aims to improve quality of life (QoL) and reduce the risk of life threatening complications. Previous reports are predominantly those with small sample sizes and short follow-up periods. The present study sought to assess a large cohort of patients for recurrence and QoL over a longer time period.MethodsThis was a follow-up study of a prospectively collected database of 455 consecutive patients. Primary repair of GHH was evaluated by endoscopy/barium meal for recurrence and a standardised symptom questionnaire for QoL. Recurrence was assessed for size, elapsed time, oesophagitis and symptoms.ResultsObjective and subjective review was achieved in 91.9% and 68.6% of patients. The median age was 69 years (range: 15–93 years) and 64% were female. Laparoscopic repair was completed in 95% (mesh in 6% and Collis gastroplasty in 7%). The 30-day mortality rate was 0.9%. The proportion of patients alive at five and ten years were 90% and 75% respectively. Postoperative QoL scores improved from a mean of 95 to 111 (p<0.01) and were stable over time (112 at 10 years). The overall recurrence rate was 35.6% (149/418) at 42 months; this was 11.5% (48/418) for hernias >2cm and 24.2% (101/418) for <2cm. The rate of new recurrence at 0–1 years was 13.7% (>2cm = 3.4%, <2cm = 10.3%), at 1–5 years it was 30.8% (>2cm = 9.5%, <2cm = 21.3%), at 5–10 years it was 40.1% (>2cm = 13.8%, <2cm = 26.3%) and at over 10 years it was 50.0% (>2cm = 25.0%, <2cm = 25.0%). Recurrence was associated with oesophagitis but not decreased QoL. Revision surgery was required in 4.8% of cases (14.8% with recurrence). There were no interval major GHH complications.ConclusionsSurgery has provided sustained QoL improvements irrespective of recurrence. Recurrence occurred progressively over ten years and may predispose to oesophagitis.
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Wu, Xiaofeng, Chijioke O. Elekwachi, Shiping Bai, Yuheng Luo, Keying Zhang und Robert J. Forster. „Characterizing the Alteration in Rumen Microbiome and Carbohydrate-Active Enzymes Profile with Forage of Muskoxen Rumen through Comparative Metatranscriptomics“. Microorganisms 10, Nr. 1 (30.12.2021): 71. http://dx.doi.org/10.3390/microorganisms10010071.

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Muskox (Ovibos moschatus), as the biggest herbivore in the High Arctic, has been enduring the austere arctic nutritional conditions and has evolved to ingest and digest scarce and high lignified forages to support the growth and reproduce, implying probably harbor a distinct microbial reservoir for the deconstruction of plant biomass. Therefore, metagenomics approach was applied to characterize the rumen microbial community and understand the alteration in rumen microbiome of muskoxen fed either triticale straw or brome hay. The difference in the structure of microbial communities including bacteria, archaea, fungi, and protozoa between the two forages was observed at the taxonomic level of genus. Further, although the highly abundant phylotypes in muskoxen rumen fed either triticale straw or brome hay were almost the same, the selective enrichment different phylotypes for fiber degrading, soluble substrates fermenting, electron and hydrogen scavenging through methanogenesis, acetogenesis, propionogenesis, and sulfur-reducing was also noticed. Specifically, triticale straw with higher content of fiber, cellulose selectively enriched more lignocellulolytic taxa and electron transferring taxa, while brome hay with higher nitrogen content selectively enriched more families and genera for degradable substrates-digesting. Intriguingly, the carbohydrate-active enzyme profile suggested an over representation and diversity of putative glycoside hydrolases (GHs) in the animals fed on triticale straw. The majority of the cellulases belonged to fiver GH families (i.e., GH5, GH6, GH9, GH45, and GH48) and were primarily synthesized by Ruminococcus, Piromyces, Neocallimastix, and Fibrobacter. Abundance of major genes coding for hemicellulose digestion was higher than cellulose mainly including GH8, GH10, GH16, GH26, and GH30, and these enzymes were produced by members of the genera Fibrobacter, Ruminococcus, and Clostridium. Oligosaccharides were mainly of the GH1, GH2, GH3, and GH31 types and were associated with the genera Prevotella and Piromyces. Our results strengthen metatranscriptomic evidence in support of the understanding of the microbial community and plant polysaccharide response to changes in the feed type and host animal. The study also establishes these specific microbial consortia procured from triticale straw group can be used further for efficient plant biomass hydrolysis.
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Dissertationen zum Thema "Ghh"

1

Lubbers, Ellen MR. „Investigation of adiponectin and its receptors in mouse-models of altered growth hormone action: Attempts to understand the link between adipose tissue and longevity“. Ohio University Honors Tutorial College / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1340185494.

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Junnila, Riia Karoliina. „In vitro characterization of human growth hormone mutants“. Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2011. http://dx.doi.org/10.18452/16311.

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Wachstumshormon (GH) besteht aus 191 Aminosäuren, hat eine Molekülmasse von 22kD und ist essentiell für postnatales Wachstum. Es wird aus der Adenohypophyse freigesetzt. GH bindet an einen GH-Rezeptor (GHR) und aktiviert somit über intrazelluläre Signalvorgänge Zielgene, insbesondere das, welches für die Kodierung von insulin-like growth factor (IGF-1) zuständig ist. IGF-1 vermittelt den Großteil aller GH-Signale. Zusammen mit den bereits bekannten GH Mutanten R77C und D112G ist in dieser Studie der neue GH Mutant d188-190 charakterisiert worden. Alle drei Mutanten wurden in heterozygoter Form in kleinwüchsigen Patienten identifiziert. Diesen Patientendaten zu Folge schien es möglich, dass d188-190 eine GH-antagonistische Wirkung besitzt. Zusätzlich wurde die extrem konservierte C-terminale Disulfidbrücke des GH im Mutanten d188-190 unterbrochen vorgefunden. Die Auswirkung der Unterbrechung wurde durch Substitution einer oder beider involvierter Cysteine durch Alanine untersucht. Alle Mutanten und Wildtypen des GH wurden in menschlichen embryonalen Nierenzellen (HEK-293) angezüchtet und eine Reihe von in vitro Experimenten sind für deren Charakterisierung etabliert worden. Es zeigte sich, dass d188-190 keine GH-antagonistische Wirkung besitzt. Im Vergleich zum Wildtyp weist der Mutant eine verminderte Bindungsaffinität zu GH, schwächere biologische Aktivität und höhere Stabilität auf. R77C und D112G sind dem Wildtyp GH sehr ähnlich. Die Disulfidbrücke ist wichtig für die Rezeptorbindung und für die biologische Aktivität von GH. Wenn ein Cystein entfernt wird vermindert sich die Stabilität des Moleküls. Dieser Effekt kann durch Entfernen des zweiten Cysteins wieder rückgängig gemacht werden. Die in dieser Studie etablierten Experimente können Verwendung finden in der Charakterisierung bislang nicht bekannter GH Mutanten und können darüber hinaus zur Behandlung von Patienten eingesetzt werden.
Growth hormone (GH) is a 22 kD, 191-aa, pituitary-derived peptide hormone that is essential for postnatal growth. GH signals via binding to GH receptor (GHR), which initiates intracellular signal transduction pathways. This leads to activation of target genes, most importantly the one encoding insulin-like growth factor (IGF)-1, which mediates most GH action. In this study a novel GH mutant, d188-190, was characterized along with previously reported GH mutants R77C and D112G. All of these mutants had been identified in heterozygous form in patients with retarded growth. Based on patient data, d188-190 was thought to be a GHR antagonist. Moreover, the extremely conserved C-terminal disulfide bridge of GH was disrupted in mutant d188-190 and its role was studied by substituting one or both of the involved cysteines with alanines. All mutants and wild type (wt) GH were produced in human embryonic kidney (HEK)-293 cells and an array of in vitro experiments was established for their characterization. It turned out that the novel d188-190 mutant is not a GHR antagonist after all. It has a diminished binding affinity to GHR, low biological activity and high stability compared to wt GH. R77C and D112G are rather similar to wt GH. The disulfide bridge is important for receptor binding and biological activity of GH. If one of the cysteines is removed the stability of the molecule drops but this can be reversed by removing both cysteines. If further GH mutants are to be identified, the established array of experiments will be useful for their fast characterization and could even contribute to correct treatment of patients.
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Tolle, Virginie. „La ghreline, une nouvelle hormone gastrointestinale se liant au récepteur des GH sécrétagogues : du contrôle de la sécrétion de l'hormone de croissance (GH) à la régulation de la prise alimentaire et des rythmes veille/sommeil“. Paris 6, 2002. http://www.theses.fr/2002PA066353.

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Liberato, Marcelo Vizoná. „Caracterização estrutural de endoglucanases da família GH5 e beta-glicosidases da família GH1: interação enzima-substrato“. Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-28012014-142924/.

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A celulose é o biopolímero de maior abundância no mundo e tem potencial para se tornar fonte de energia renovável através de sua transformação em açúcares fermentáveis, que por sua vez serão transformados em etanol. A recalcitrância da celulose, principal dificuldade encontrada no processo, pode ser superada com o auxílio de enzimas (celulases). Ao menos três enzimas celulolíticas são necessárias para a degradação total da celulose, incluindo as celobioidrolases, que hidrolisam as ligações glicosídicas das extremidades redutoras e não redutoras da cadeia, as endoglucanases, que clivam a cadeia de celulose amorfa randomicamente, e as beta-glicosidases, que produzem glicose através dos celo-oligômeros. Mas para que esse processo se torne financeiramente viável é necessário conhecer o funcionamento, otimizar a atividade e aumentar a produção dessas celulases. Com o intuito de avançar na compreensão da função e estrutura dessas enzimas, o presente trabalho teve como objetivo o estudo estrutural de beta-glicosidases da família GH1 e endoglucanases da família GH5. Na primeira parte do trabalho, a expressão da endoglucanase II de Trichoderma reesei não foi alcançada, mesmo utilizando diferentes organismos e condições de expressão. Porém, na segunda etapa, foi obtida a expressão, purificação e os primeiros ensaios de cristalização de 11 beta-glicosidases bacterianas da família GH1 e 8 endoglucanases bacterianas da família GH5. Dentre elas, três beta-glicosidases e uma endoglucanase de Bacillus licheniformis foram cristalizadas e tiveram sua estrutura resolvida. As beta-glicosidases, apesar de possuírem o enovelamente similar, apresentaram variações no tamanho e posição das alças formadoras da fenda catalítica e divergem em relação a um dos aminoácidos importantes para a estabilização do substrato. Essas diferenças podem ajudar a explicar o mecanismo dessas enzimas para reconhecer substratos distintos. A endoglucanase da família GH5, possuindo dois módulos acessórios, foi cristalizada tanto na forma apo quanto complexada ao substrato celotetraose. O segundo módulo acessório possivelmente é um domínio de ligação à celulose (CBM) e seus resíduos aromáticos, que são responsáveis pela interação com o substrato, parecem complementar o sítio catalítico, sendo assim um novo mecanismo de auxílio enzimático de um CBM. O primeiro módulo acessório não possui um aparente sítio de interação com carboidratos e provavelmente funciona como um conector entre domínio catalítico e o CBM. O posicionamento do substrato no sítio de ligação é parecido com outras estruturas já determinadas, porém, suscita algumas dúvidas sobre a função dos resíduos catalíticos que é conservada na família. O carbono anomérico do substrato possui uma densidade eletrônica contínua com o glutamato da fita β4 (que deveria ser o ácido/base) e está mais próximo dele que do glutamato da fita β7 (que deveria ser o nucleófilo).
Cellulose is the most abundant biopolymer in the world and can become a renewable energy source through its transformation in fermentable sugars, which will be converted in bioethanol. The cellulose recalcitrance, main difficulty in the process, can be overcome with the aid of enzymes (cellulases). At least three cellulolytic enzymes are required for complete hydrolysis of cellulose, including cellobiohydrolases for hydrolyzing the glycosidic linkages from the reducing and non-reducing chain ends, endoglucanases for randomly cleaving cellulose chains in the amorphous regions, and beta-glucosidases for producing glucose from the solubilized cello-oligomers. But, to become a financially viable process it is necessary to know the mechanism, optimize the activity and improve the production of these cellulases. In order to advance the understanding of the structure and function of these enzymes, the present work intended to study the structure of beta-glucosidases from family GH1 and endoglucanases from family GH5. In the first part of the work, the expression of endoglucanase II from Trichoderma reesei was not achieved, even using different organisms and expression conditions. However, in the second part, the expression, purification and the crystallization first trials of eleven bacterial beta-glucosidases and eight bacterial endoglucanases were achieved. Among them, three beta-glucosidases and one endoglucanase from Bacillus licheniformis were crystallized and had their structures solved. Beta-glucosidases, although having a similar folding, showed variations in the length and position of the loops that form the catalytic cleft and diverge in relation to one of the amino acids that are important in substrate stabilization. These differences may help explain the mechanism of these enzymes to recognize distinct substrates. The endoglucanase, which has two accessory modules, was crystallized in the apo form and complexed with the substrate celotetraose. The second accessory module probably is a cellulose binding domain (CBM) and its aromatic residues, which are responsible for the substrate interaction, seem to complement the catalytic site. Therefore it can be a new mechanism of CBM assistance in the enzymatic activity. The first accessory module has no apparent interaction site with carbohydrates and probably works as a connector between the catalytic domain and CBM. The positioning of the substrate in the binding site is similar to other structures already solved but raises some questions about the role of the catalytic residues, that are conserved in the family. The anomeric carbon of the substrate has a continuous electron density with glutamate from sheet-β4 (which should be the acid/base) and is closer to it than to glutamate from sheet-β7 (which should be the nucleophile).
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Mear, Yves. „Implication de l'activité constitutive du récepteur de la ghréline dans la tumorigenèse des adénomes somatotropes“. Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM5102.

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Les adénomes hypophysaires sont les tumeurs intracérébrales les plus fréquentes. Les adénomes somatotropes hypersécrètent l’hormone de croissance (GH) et sont traités classiquement par des analogues somatostatinergiques. Une petite moitié des patients acromégales est néanmoins résistante à ces traitements. L’on sait depuis, quelques années, que le récepteur de la ghréline possède une forte activité constitutive et joue un rôle majeur dans la sécrétion de GH. Cette activité constitutive est-elle impliquée dans la tumorigenèse des adénomes somatotropes ? Nos travaux ont montré un niveau de transcrits, codant pour le GHS-R, particulièrement élevé dans ces tumeurs, et l’immunocytochimie révèle un marquage punctiforme localisé à la membrane plasmique. La MSP (agoniste inverse du GHS-R) induit une diminution dose-dépendante de la sécrétion de GH des cultures primaires d’adénomes somatotropes. Cette efficacité de la MSP sur la sécrétion de l’hormone de croissance est particulièrement remarquable sur les patients résistants aux agonistes somatostatinergiques chez qui elle démontre une efficacité relative accrue. Des clones, surexprimant le GHS-R humain (lignées MYST-R), ont été générés à partir de lignées somato-lactotropes tumorales de rat (GH4C1). Sur ces cellules, le ligand endogène du GHS-R induit une augmentation d’IP3 intracellulaire. De façon originale, la MSP induit une diminution du niveau d’IP3 intracellulaire. L’inhibition de l’activité constitutive du GHS-R par un agoniste inverse, tel que la MSP, pourrait permettre de réprimer l’hypersécrétion de GH, faisant de cette molécule une alternative pharmacologique aux traitements actuels des adénomes somatotropes
Pituitary tumors are most usual intracranial tumors. The somatotroph adenomas are characterised by a GH hypersecretion. The current treatments are based on somatostatinergic agonists. Unfortunately, there is steel 50% of patients, which remain insensitive to these treatments. The aim of our work was to find a pharmacological alternative to treat the patients resistant to the current therapies. Ghrelin stimulate pituitary GH release in vivo through GHS-R1a activation. Interestingly, this receptor transduces signal through an unusual high constitutive activity. Noteworthy, human somatotroph adenomas expressed a high level of GHS-R1a at both mRNA and protein level. We actually assess the implication of this constitutive activity in the tumorigenesis of the somatotroph adenomas. Firstly we demonstrated GHS-R1a functionality through its capacity to fixe endogenous ligand. Then we showed that treatment of human somatotroph adenomas primary cultures, with the GHS-R1a inverse agonist (MSP: Modified Substance P), induced a dose dependent decrease of GH secretion. To foremost investigate the transduction mechanisms underlying these results, we developed, from GH4C1 (rat somato-lactotroph tumoral cell line), stable monoclonal cell lines overexpressing human GHS-R1a (named MYST-Rg). Interestingly MYST-Rg cells exhibit relatively high basal activation of the IP3 pathway. GHS-R1a endogenous ligand (ghrelin) strengthens basal IP3 pathway activation of MYST-Rg cells. Noteworthy, the basal IP3 pathway activation can be lessened by MSP treatment. Thus, MSP could be a useful alternative to the current therapies of somatotroph adenomas
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Araújo, Juscemácia Nascimento. „Sintese e caracterizacao de nanoparticulas de prata assistidas por B-glicosidases (GH1 e GH3) de Thermotoga petrophila“. reponame:Repositório Institucional da UFABC, 2017.

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Orientador: Prof. Dr. Wanius José Garcia da Silva
Dissertação (mestrado) - Universidade Federal do ABC, Programa de Pós-Graduação em Biotecnociência, 2017.
A hidrolise enzimatica da celulose e realizada pela acao sinergica de pelo menos tres tipos de celulases distintas: endoglucanases, exoglucanases e B.glicosidases. As endoglucanases e celobiohidrolases sao frequentemente inibidas pelo aumento da concentracao de celobiose (dimero de glicose) no meio reacional. As ¿À-glicosidases sao enzimas que clivam celobiose em monomeros de glicose. Portanto, as B-glicosidases sao essenciais ao processo de hidrolise da celulose por impedirem o acumulo de celobiose e, assim, evitar a diminuicao da taxa de hidrolise. Processos de pre-tratamento da biomassa lignocelulosica sao empregados, antes da reacao de hidrolise enzimatica da celulose, a fim de retirar a fracao de lignina e aumentar a taxa de conversao da celulose em glicose. Porem, estes processos de pre-tratamento da biomassa lignocelulosica nao sao 100% eficientes na remocao da lignina. Estudos previos mostraram que a adicao de lignina a celulose pura pode causar a reducao da liberacao de acucar em valores superiores a 60%. Assim, neste estudo, nos caracterizamos a adsorcao nao produtiva da enzima ¿À-glicosidase da familia GH1 da bacteria Thermotoga petrophila (TpBGL1) em ligninas extraidas de diferentes biomassas (cana-de-acucar e eucalipto). Em pH 7 e 6, nossos resultados indicaram que a repulsao eletrostatica enfraquece a adsorcao nao produtiva de TpBGL1 em ligninas. Contudo, em pH 4 a atracao eletrostatica fortalece a adsorcao nao produtiva. Alem disso, o aumento da temperatura de 25 oC para 70 oC nao resultou em um aumento significativo da adsorcao de TpBGL1 em ligninas, provavelmente porque nao ocorre um aumento significativo de regioes hidrofobicas na estrutura da enzima expostas ao solvente. Todas as informacoes obtidas neste estudo poderao ser uteis para aplicacoes biotecnologicas no campo de conversao de polissacarideos estruturais em bioenergia.
The B-glucosidases are a group of important enzymes employed in a large number of industrial applications. In this study, we reported for the first time the photobiosynthesis of stable and functional silver nanoparticles (AgNPs) using two hyperthermostable bacterial â-glucosidases with industrial potential. The syntheses were simple and rapid processes carried out by mixing â-glucosidases and silver solution under irradiation with light (450-600 nm), therefore, compatible with the green chemistry methodology. The synthesized AgNPs were characterized using a series of physical techniques. Absorption spectroscopy showed a strong absorption band at 460 nm due to surface plasmon resonance of the AgNPs. X-ray diffraction analysis showed that the AgNPs were purely crystalline in nature. Electron microscopy showed AgNPs of variable diameter ranging from 20 to 100 nm. In addition, electron microscopy, zeta potential and Fourier transform infrared spectroscopy results confirmed the presence of â-glucosidases coating and stabilizing the AgNPs. The results also showed that the enzymatic activities were maintained in the â-glucosidases assisted AgNPs. The data described in this study should provide a useful basis for future studies of â-glucosidases assisted AgNPs, including biotechnological applications.
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Kearney, Tara Maria. „The effect of growth hormone replacement (GHR) apolipoprotein B100 (apoB) kinetics in growth hormone deficient (GHD) hypopituitary subjects“. Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272425.

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Sadhukhan, Sushabhan. „Metabolism & Signaling of 4-Hydroxyacids: Novel Metabolic Pathways and Insight into the Signaling of Lipid Peroxidation Products“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1339171892.

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Nascif, Sergio de Oliva [UNIFESP]. „Efeitos da ghrelina, GHRP-6 e GHRH sobre a secreção de GH, ACTH e cortisol no hipertireoidismo“. Universidade Federal de São Paulo (UNIFESP), 2008. http://repositorio.unifesp.br/handle/11600/23916.

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Made available in DSpace on 2015-12-06T23:47:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2008
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Estudo 1 - A ghrelina demonstrou ser um estímulo mais potente do que o GHRP-6 e o GHRH para a secreção de GH em controles e em pacientes com hipertireoidismo. Porém, a resposta do GH após todos os estímulos foi menor na tireotoxicose quando comparada aos indivíduos normais. Portanto, o excesso de hormônios tireoidianos interfere com as vias hipotalâmicas e hipofisárias de liberação de GH ativadas por ghrelina, GHRP-6 e GHRH. Os valores basais de glicemia dos pacientes com hipertireoidismo não foram significativamente diferentes dos observados em controles. A ghrelina promoveu um aumento similar nas concentrações plasmáticas de glicose em ambos os grupos, enquanto que o GHRP-6 não alterou os níveis circulantes de glicose. Portanto, o excesso de hormônios tireoidianos não interfere nos mecanismos de liberação de glicose estimulados pela ghrelina. Estudo 2 - Foi observado um aumento nos valores basais de ACTH e de cortisol nos pacientes com hipertireoidismo comparado com controles, sugerindo que o excesso de hormônios tireoidianos interfere com o eixo hipotálamo-hipófise adrenal. A administração da ghrelina promoveu uma liberação maior de ACTH e de cortisol em ambos os grupos, confirmando que a ghrelina é um estímulo potente para ativação do eixo hipotálamo-hipófise adrenal. A resposta do cortisol à ghrelina e ao GHRP-6 em pacientes com hipertireoidismo foi semelhante a dos controles. A liberação de ACTH após ghrelina na tireotoxicose foi maior que em indivíduos normais, enquanto que com GHRP-6 os valores não alcançaram significância estatística. Nossos dados sugerem que as vias de liberação de ACTH estimuladas pela ghrelina são ativadas pelo excesso de hormônios tireoidianos, porém sem repercussões significativas na resposta adrenocortical..
BV UNIFESP: Teses e dissertações
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Albanes, Stalin F. „1.2 GHz and 2.4 GHz LEO satellite communications“. Thesis, Queensland University of Technology, 1995. https://eprints.qut.edu.au/35994/1/35994_Albanes_1995.pdf.

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This report outlines the steps taken to design and develop a 1.2 GHz and 2.4 GHz LEO satellite communication facility at the QUT satellite ground station to allow experimentation and communication links with low earth orbiting (LEO) satellites. The design, setup, construction, testing and installation of the antenna system required by the QUT satellite ground station to operate in the 1.2 GHz and 2.4 GHz frequency bands are described. Existing ground station capabilities and limitations were studied and a complete operational satellite station is suggested for the future to further perform telemetry, tracking and command control. Upgrading the ground station to 1.2 and 2.4 GHz will enable QUT to proceed with investigations and trials on other space related projects.
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Bücher zum Thema "Ghh"

1

Sihnā, Prabhāta. Gho' gho' rāṇī. Kaṭaka: Oḍiśā Buk Shṭora, 1994.

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Stermilli, Haki. Sikur te isha djale: Roman. Tirane: Shtepia Botuese "Letrat", 2002.

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Scheunemann, Pam. Ght. Edina, Minn: Abdo Pub., 2001.

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D, Hansson Gunnar. GDH. Göteborg: Litterär gestaltning, Göteborgs universitet, 2010.

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Pierre, Richard. GHB. [Boisbriand, Québec]: Pratiko, 2007.

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Bleasdale, Alan. GBH. London: Hutchinson, 1987.

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Hò̂, Biẻ̂u Chánh. Mẹ ghẻ con ghẻ: Tiẻ̂u thuyé̂t. [Tiè̂n Giang]: Nhà xuá̂t bản tỏ̂ng hợp Tiè̂n Giang, 1988.

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Proceedings, of the Third International Symposium on the Gerasimov-Drell-Hearn Sum Rule and Its Extensions (. GDH 2004. Singapore: World Scientific Publishing, 2005.

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Khayat, S. A. Gour gah. Tehran: Hirmand, 1999.

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Hiền, Quý. Muon ghe. Hà Nội: Nhà xuất bản Sân khấu, 2003.

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Buchteile zum Thema "Ghh"

1

Frohman, Lawrence A. „Physiology of the Growth Hormone Releasing Hormone-Somatostatin-Growth Hormone-Insulin-Like Growth Factor I Axis“. In GHRH, GH, and IGF-I, 3–10. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_1.

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Ziegler, Thomas R. „Administration of Growth Hormone as an Adjunct to Nutritional Support in Critical Illness“. In GHRH, GH, and IGF-I, 91–109. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_10.

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Festoff, Barry W., Shi X. Yang und David Stong. „Strategies for the Use of Recombinant Human Growth Hormone and Insulin-Like Growth Factor I in Amyotrophic Lateral Sclerosis“. In GHRH, GH, and IGF-I, 110–28. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_11.

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Werther, George A. „Contemporary Issues in Growth and Development: An Overview“. In GHRH, GH, and IGF-I, 131–35. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_12.

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Rosenfeld, Ron G., Arlan L. Rosenbloom und Jaime Guevara-Aguirre. „Use of Recombinant IGF-I in Syndromes of GH Insensitivity“. In GHRH, GH, and IGF-I, 136–42. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_13.

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Bercu, Barry B., Howard J. Heinze und Richard F. Walker. „Use of Growth Hormone in Non-Growth-Hormone-Deficient Children: Physiologic, Pharmacologic, and Ethical Issues“. In GHRH, GH, and IGF-I, 143–68. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_14.

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Christiansen, Jens S., Jens O. L. Jørgensen, Nina Vahl, Anders Juul, Jørn Müller und Niels E. Skakkebæk. „Growth Hormone Treatment of Nonelderly Adults with GH Deficiency“. In GHRH, GH, and IGF-I, 169–75. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_15.

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Melmed, Shlomo. „Overview of Growth Hormone and IGF-I Effects on Intermediary Metabolism and Bone“. In GHRH, GH, and IGF-I, 179–84. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_16.

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Copeland, Kenneth C., und K. Sreekumarun Nair. „Effects of rhGH on Glucose, Lipid, and Amino Acid Metabolism“. In GHRH, GH, and IGF-I, 185–94. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_17.

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Sherwin, Robert S., Walter P. Borg und Susan D. Boulware. „Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus“. In GHRH, GH, and IGF-I, 195–203. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5_18.

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Konferenzberichte zum Thema "Ghh"

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Bauermeister, Kurt J., Bernhard Schetter und Klaus D. Mohr. „A 9.25 MW Industrial Gas Turbine With Extreme Low Dry NOx and CO Emissions“. In ASME 1993 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/93-gt-307.

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In cooperation between Siemens and MAN GHH an industrial gas turbine with an ISO rating of 9.2 5 MW was equipped with a dry low NOx combustion system. Using the hybrid burners of Siemens gas turbines, a new combustion chamber was developed for the gas turbine THM 1304 of MAN GHH. This gas turbine has two V-like arranged combustion chambers, which allow a redesign of the combustion chamber, without changing the remaining parts of the gas turbine and its casing. So it is possible as well, to fit present machines with new combustion chambers. The combustion chambers contain flame tubes of Siemens technology with ceramic tiles and the well proved hybrid burners. After calculation and design the air flow was examined in an isothermal flow model. Finally two prototypes of the combustion chamber mounted on a THM 1304 gas turbine were tested at the MAN GHH gas turbine test bed. Success came very quickly and the test runs are finished now. So for the first time the transfer of the well-known low emission values of the Siemens large scale gas turbines succeeded to an industrial gas turbine of the 10 MW class.
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Attia, Mohammed, Younes Samih, Manaal Faruqui und Wolfgang Maier. „GHH at SemEval-2018 Task 10: Discovering Discriminative Attributes in Distributional Semantics“. In Proceedings of The 12th International Workshop on Semantic Evaluation. Stroudsburg, PA, USA: Association for Computational Linguistics, 2018. http://dx.doi.org/10.18653/v1/s18-1155.

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Prario, Aldo, und Heinrich Voss. „FT8A, a New High Performance 25 MW Mechanical Drive Aero Derivative Gas Turbine“. In ASME 1990 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1990. http://dx.doi.org/10.1115/90-gt-287.

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This paper describes the FT8A, an advanced state of the art, high performance aeroderivative gas turbine under development for variable speed mechanical drive industrial applications. The gas generator, common to the recently developed FT8, is derived from the Pratt & Whitney JT8D-200 series aircraft engine. The power turbine is being designed and developed by Turbo Power and Marine Systems, Inc. (TPM) and MAN Gutehoffnungshütte AG (MAN GHH) under a joint collaboration program. The power turbine features a three stage rotor simply supported between antifriction bearings, advanced aerodynamics, and a low loss exhaust diffuser/collector system. Design features, performance and typical applications of the FT8A are presented.
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Orth, U., H. Ebbing, H. Krain, A. Weber und B. Hoffmann. „Improved Compressor Exit Diffuser for an Industrial Gas Turbine“. In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0323.

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Cycle studies carried out for the medium pressure ratio gas turbine THM 1304 of 10 MW power output manufactured by MAN Turbomaschinen AG GHH BORSIG predicted that the overall efficiency of the multi stage compressor, composed of a 10 stage axial and a single stage centrifugal compressor, would improve by 0.8% if the efficiency of the back stage centrifugal unit could be raised by 4%. It was expected that this would result in a noticeable improvement of the thermal gas turbine efficiency. The paper describes the aerodynamical design process used for the stage optimization applying today’s advanced design tools for blade generation and three dimensional aerodynamic calculation methods. Additionally it describes the manufacturing procedure for the resulting three-dimensional blades and the experimental verification of the design approach.
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Schlein, Barry C., David A. Anderson, Markus Beukenberg, Klaus D. Mohr, Hans L. Leiner und Wolfgang Träptau. „Development History and Field Experiences of the First FT8 Gas Turbine With Dry Low NOx Combustion System“. In ASME 1999 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/99-gt-241.

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This paper describes the FT8-2 Dry Low NOx (DLN) combustor development process and reviews the development history and initial field experience at a natural gas pipeline station in Germany. The development process is primarily focused on defining a fuel nozzle or injector, investigating emissions, fuel-air mixing, flame stability, acoustics, flashback resistance, and flame disgorgement. Empirical development tools including single nozzle and sector combustion rigs, as well as flame imaging techniques, are discussed. A summary of in-house engine development testing is provided. The control methodology used to meet emissions, while maintaining combustor pressure pulsations at an acceptable level, is provided. The natural gas compressor station design and operational experience with a GHH BORSIG compressor driven by the FT8 engine in Werne, Germany is summarized. Also presented are details of the very short conversion period from Standard to DLN combustor with the first successful ignition of the engine 26 days after work had begun.
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6

Blaswich, Michael, und Derek J. Taylor. „Effects of Variable Inlet Guide Vane Settings on Axial Compressor Blade Vibration in an Industrial Gas Turbine“. In ASME 1998 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/98-gt-361.

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This paper describes an experiment on a GHH BORSIG Type THM 1304-10 Gas Turbine engine to test the effects of variable vane setting on the vibration behaviour of the blades in all 10 stages of the axial compressor. The rotor was fitted with a network of strain-gauges. An analogue telemetry system was arranged using standard hardware and special application software to display in real-time and to log the full range of frequencies and amplitudes for all instrumented blades. The data acquisition system is described together with a presentation of the live display which allowed engineers to interact with measured results to maximise the benefits of the test whilst all strain-gauges were still functional. Tests were arranged to maximise the vibration data collected at all points before gauge mortality was experienced. Prior to the test, blades were vibrated statically to determine shapes of the first four vibration modes. The paper discusses the fixing techniques for the gauges, the modal shape measurement technique and the calibration of the strain-gauges. The telemetry system architecture and multiplexing arrangement are described together with examples of typical test data and the conclusions concerning the effects on blade vibration of different variable inlet guide vanes (IGV) settings.
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Bauermeister, K. J., H. J. Dohmen und H. Simon. „Numerical Investigations on the Effects of Swirling Combustor Exit Flow on HP-Turbine Inlet Flow for the Industrial Gas Turbine THM 1304“. In ASME 1993 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/93-gt-256.

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To reduce gas turbine exhaust emissions the combustion system of the MAN GHH industrial gas turbine THM 1304 (ISO power 9250 kW) has been modified. The two outboard combustors in a V–configuration enabled to enlarge the chambers and thus to increase the retention time. Compared to the initial design the nature of combustor exit flow is considerably changed to an additional swirling flow. To estimate the effects of these flow conditions on gas turbine performance the flow towards the high pressure turbine should be investigated. For that purpose a numerical flow simulation in the casing between the combustion chambers and the high pressure turbine nozzles has been accomplished. A Navier–Stokes–Solver (Finite Element Method) has been applied to the computation of the threedimensional turbulent flow. The essential results, especially the flow conditions in front of the HP–turbine nozzles are presented with respect to the idealized combustor exit flow conditions. Besides the swirl strength, the direction of rotation and the swirl relation are varied. It is shown, that the flow at HP–turbine inlet is essentially characterized by the mainly centripetally directed combustor exit flow. Dependent on the above mentioned swirl flow parameters the characteristic flow distribution at HP–turbine inlet changes more or less. In the most favourable case the mass flow distribution at HP–turbine inlet varies circumferentially approx. ±14% and in the worst case approx. ±26%. Associated deviations from the ideal axial flow direction of approx. ±30° respectively ±40° are calculated.
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Porras, Frank, Angel D. Ramirez, Arnaldo Walter und Guillermo Soriano. „Life Cycle Assessment of Greenhouse Gas Emissions: Comparison Between a Cooling Tower and a Geothermal Heat Exchanger for Air Conditioning Applications in Ecuador“. In ASME 2019 13th International Conference on Energy Sustainability collocated with the ASME 2019 Heat Transfer Summer Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/es2019-3907.

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Abstract Cooling towers are widely used to remove heat in buildings with chilled water air conditioning systems. Moreira et al. [1] performed an experimental comparison between a cooling tower (CT) and a geothermal heat exchanger (GHE) in Guayaquil-Ecuador (hot/humid climate) and the results show an advantage of 39% of GHE systems regarding energy efficiency. This study compares the emissions of greenhouse gases (GHG), considering the results of the research mentioned above and comparing both systems. A life cycle assessment (LCA) approach was used to estimate the GHG emissions, assuming three scenarios for the electricity supply: the electricity generation mix in 2016, the planned electricity generation mix in 2025, and the profile for marginal electricity generation (peak demand). The estimated reduction of GHG emissions due to the use of GHE systems could be up to 50%. GHEs for building air conditioning applications is a technological option with potential to reduce energy consumption and GHG emissions. However, additional work is necessary to evaluate the complete environmental profile and its cost-effectiveness.
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Abuelyamen, Ahmed, und Mohand H. Mohamed. „Techno-Economic Study of Installing 10 MW PV Power Plant in Sudan“. In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-66996.

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This work investigates the installation of a 10 MW solar PV power plant in a sustainable city in Sudan. Initially, the climatic data such as relative humidity, temperature and horizontal solar radiation over 30 cities in Sudan were collected from NASA web page, then the behavior of all climatic data was analyzed. Annual daily solar radiation on a tilted surface was also calculated over the 30 locations around the country. It was found that the maximum value of tilted average solar radiation is 6.61 KWh/day at Dungola from fixed mode and 8.93 kWh/m2/day from tracking mode. Consequently, the location was selected as an optimum spot for building the solar PV power plant. Additionally, the available solar PV panels on the market were judged according to the maximum module efficiency and high ratio value of module capacity to frame area. The project lifetime is considered as 25 years. RETScreen v.4 software was used to simulate the feasibility analysis of the project based on electric power generated from fixed and tracking modes of operation, financial analysis and greenhouse gas emissions. The study showed that, technically, the proposed plant can generate up to 16.209 GWh of electric energy annually from the fixed system and 21.828 GWh from the tracking system. Environmentally, the annual net GHG reduction is 16,000 and 21,600 tons of CO2 from fixed and tracking systems respectively. From a financial standpoint, the cost-effective indicators were calculated and it was found that the IRR and payback period for the fixed system plant were 0.6% and 23.6 years, respectively. While for tracking system plant, figures were 2.66% and 19.4 years, respectively.
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Liu, Xueli, Shun Yao, John Gibson und Stavros V. Georgakopoulos. „Frequency Reconfigurable QHA Based on Kapton Origami Helical Tube for GPS, Radio and WiMax Applications“. In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-68048.

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Origami tubes are deployed to realize a compactable and frequency reconfigurable quadrifilar helical antenna (QHA). The specific origami pattern is parametrically analyzed to help with antenna modelling and simulation at reconfigurable states. Two quadrifilars respectively on helical tube and bellow tube are proposed, and the quadrifilar on helical tube is fabricated with 4-mil Kapton substrate. Measured results show that this Kapton QHA can operate with right-handed circularly polarized (RHCP) radiation patterns at 4 reconfigurable states with: ±1dB RHCP gain bandwidth from 1.05 GHz-1.4 GHz at state 1 with total antenna height H = 203 mm; ±1dB RHCP gain bandwidth from 1.4 GHz-1.73 GHz at state 2 with total antenna height H = 168 mm; ±1dB RHCP gain bandwidth from 2.07 GHz-2.7 GHz at state 3 with total antenna height H = 69 mm; ±1dB RHCP gain bandwidth from 2.7 GHz-2.94 GHz and 3.26 GHz-3.66 GHz at state 4 with total antenna height H = 54 mm. Therefore, this antenna can be reconfigured and applied in space and remote communication applications, such as GPS (1.17 GHz-1.58 GHz), radio (2.305 GHz-2.315 GHz) and WiMax (3.5 GHz).
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Berichte der Organisationen zum Thema "Ghh"

1

Bergeron, G., M. Czarnaski und M. Rhinewine. Scaling of an 85 GHz Gyrotron to Operate at 94 GHz. Fort Belvoir, VA: Defense Technical Information Center, September 1989. http://dx.doi.org/10.21236/ada212756.

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2

Skone, Timothy J. Indirect Land Use GHG. Office of Scientific and Technical Information (OSTI), Dezember 2012. http://dx.doi.org/10.2172/1509279.

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3

Barnum, Thomas J. A 94 GHz Transmissometer. Fort Belvoir, VA: Defense Technical Information Center, Mai 1990. http://dx.doi.org/10.21236/ada223309.

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4

Kreischer, Kenneth, Jack Tucek, Mark Basten und David Gallagher. Integrated 220 GHz Source Development. Fort Belvoir, VA: Defense Technical Information Center, Mai 2014. http://dx.doi.org/10.21236/ada610341.

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5

Skone, Timothy J. Direct Land Use GHG, Reversion. Office of Scientific and Technical Information (OSTI), August 2013. http://dx.doi.org/10.2172/1509272.

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6

Crane, Robert K. 5/15 GHZ Scattering Study. Fort Belvoir, VA: Defense Technical Information Center, Mai 1991. http://dx.doi.org/10.21236/ada236350.

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7

Hejdenberg, Jennie. Improving GHB withdrawal with baclofen. National Institute for Health Research, Juli 2021. http://dx.doi.org/10.3310/nihropenres.1115156.1.

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8

Hirshfield, Jay L. SEVENTH HARMONIC 20 GHz CO-GENERATOR. Office of Scientific and Technical Information (OSTI), April 2014. http://dx.doi.org/10.2172/1127219.

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9

Temkin, Richard J., und Michael A. Shapiro. 17 GHz High Gradient Accelerator Research. Office of Scientific and Technical Information (OSTI), Juli 2013. http://dx.doi.org/10.2172/1087178.

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10

Fliflet, A. W., R. P. Fischer, D. Lewis, Rayne III, Bender R. J. und B. D. Microwave Sintering Studies at 2.45 GHz. Fort Belvoir, VA: Defense Technical Information Center, Juli 1997. http://dx.doi.org/10.21236/ada328545.

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