Auswahl der wissenschaftlichen Literatur zum Thema „Forensic Drugs“

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Zeitschriftenartikel zum Thema "Forensic Drugs"

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Drummer, Olaf H. „Drugs and Forensic Science“. Australian Journal of Forensic Sciences 33, Nr. 1 (Januar 2001): 1. http://dx.doi.org/10.1080/00450610109410805.

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AŞICIOĞLU, Faruk, Emre MUTLU und Mustafa OKUDAN. „Driving Under the Influence of Drugs“. Turkiye Klinikleri Journal of Forensic Medicine and Forensic Sciences 16, Nr. 3 (2019): 164–73. http://dx.doi.org/10.5336/forensic.2019-65818.

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Peltier-Rivest, Dominic, und Carl Pacini. „Detecting counterfeit pharmaceutical drugs“. Journal of Financial Crime 26, Nr. 4 (07.10.2019): 1027–47. http://dx.doi.org/10.1108/jfc-06-2018-0057.

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Purpose This paper aims to analyze drug counterfeiting, explains its risk factors and operating and legal environments reviews recent legal cases and develops a multi-stakeholder prevention strategy that includes forensic accounting methods. Design/methodology/approach This is a theoretical study based on legal case studies and the best forensic accounting strategies. Findings Pharmaceutical drug counterfeiting is a fast-growing fraud that so far has attracted little attention from forensic accountants. A recent estimate projects that criminals collect around $75bn annually in illicit sales from counterfeit drugs (Bairu, 2015). Pharmaceutical counterfeiting also leads to the loss of lives when criminals use lethal chemicals in the manufacturing of fake medicines (Liang, 2006a; Brown, 2005). Because the detection of drug counterfeiting is extremely difficult after fake medicines have been ingested by patients, the strategy developed in this paper is based on early discovery by using reliable tracking technologies and inventory management controls in the supply chain, conducting effective regulatory and legitimate customs inspections, and increasing consumer awareness of basic forensic accounting tools. Research limitations/implications This paper extends previous research by integrating various factors into a single multi-stakeholder prevention framework. Practical implications The paper presents a synthesized, comprehensive view of the drug fraud epidemic and analyzes concrete steps that can be taken to protect the pharmaceutical supply chain to reduce the loss of lives and monetary injuries. Originality/value No previous research has analyzed this issue from a multi-stakeholder point of view and used forensic accounting tools to complement a prevention strategy. The drug counterfeiting prevention strategy developed in this paper addresses the supply side, the regulatory enforcement side and the demand side.
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Anderson,, Peter D., Kimmy Naik, Chenery Kinemond und Anne ImObersteg. „Forensic Testing for Drugs of Abuse“. Journal of Pharmacy Practice 13, Nr. 3 (01.06.2000): 226–35. http://dx.doi.org/10.1106/9hvx-72mk-cd0x-0u8c.

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Anderson, Peter D., Kimmy Naik, Chenery Kinemond und Anne ImObersteg. „Forensic Testing for Drugs of Abuse“. Journal of Pharmacy Practice 13, Nr. 3 (Juni 2000): 226–35. http://dx.doi.org/10.1177/089719000001300311.

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Forensic urine drug testing (FUDT) is a tool of many employers to assess drug use in employees. Collegiate and professional sports test for banned substances. Immunoassays are often the screening test. Gas chromatography/mass spectrometry is the confirmatory test. Numerous foods and medications interfere with test results. Safeguards in FUDT include chain of custody procedures, certification of laboratories and personnel, cutoff values, quality assurance and quality control procedures, and medical review officers. Breath analysis is used in drunk-driving cases. Blood and hair can also be analyzed for substances of abuse. Pharmacists can be an asset in drug testing issues.
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Flanagan, R. J. „The Forensic Pharmacology of Drugs of Abuse“. British Journal of Clinical Pharmacology 56, Nr. 3 (04.08.2003): 345–46. http://dx.doi.org/10.1046/j.1365-2125.2003.01891.x.

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Labadie, Jerry. „Forensic pharmacovigilance and substandard or counterfeit drugs“. International Journal of Risk & Safety in Medicine 24, Nr. 1 (2012): 37–39. http://dx.doi.org/10.3233/jrs-2012-0551.

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McBay, Arthur J., und Andrew P. Mason. „Forensic Science Identification of Drugs of Abuse“. Journal of Forensic Sciences 34, Nr. 6 (01.11.1989): 12789J. http://dx.doi.org/10.1520/jfs12789j.

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Singer, Raymond. „The Forensic Pharmacology of Drugs of Abuse“. International Journal of Toxicology 21, Nr. 5 (September 2002): 436–37. http://dx.doi.org/10.1177/109158180202100519.

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Maciów-Głąb, Martyna, Sebastian Rojek, Karol Kula und Małgorzata Kłys. „“New designer drugs” in aspects of forensic toxicology“. Archives of Forensic Medicine and Criminology 1 (2014): 20–33. http://dx.doi.org/10.5114/amsik.2014.44587.

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Dissertationen zum Thema "Forensic Drugs"

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Swortwood, Madeleine Jean. „Comprehensive Forensic Toxicological Analysis of Designer Drugs“. FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/997.

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New designer drugs are constantly emerging onto the illicit drug market and it is often difficult to validate and maintain comprehensive analytical methods for accurate detection of these compounds. Generally, toxicology laboratories utilize a screening method, such as immunoassay, for the presumptive identification of drugs of abuse. When a positive result occurs, confirmatory methods, such as gas chromatography (GC) or liquid chromatography (LC) coupled with mass spectrometry (MS), are required for more sensitive and specific analyses. In recent years, the need to study the activities of these compounds in screening assays as well as to develop confirmatory techniques to detect them in biological specimens has been recognized. Severe intoxications and fatalities have been encountered with emerging designer drugs, presenting analytical challenges for detection and identification of such novel compounds. The first major task of this research was to evaluate the performance of commercially available immunoassays to determine if designer drugs were cross-reactive. The second major task was to develop and validate a confirmatory method, using LC-MS, to identify and quantify these designer drugs in biological specimens. Cross-reactivity towards the cathinone derivatives was found to be minimal. Several other phenethylamines demonstrated cross-reactivity at low concentrations, but results were consistent with those published by the assay manufacturer or as reported in the literature. Current immunoassay-based screening methods may not be ideal for presumptively identifying most designer drugs, including the “bath salts.” For this reason, an LC-MS based confirmatory method was developed for 32 compounds, including eight cathinone derivatives, with limits of quantification in the range of 1-10 ng/mL. The method was fully validated for selectivity, matrix effects, stability, recovery, precision, and accuracy. In order to compare the screening and confirmatory techniques, several human specimens were analyzed to demonstrate the importance of using a specific analytical method, such as LC-MS, to detect designer drugs in serum as immunoassays lack cross-reactivity with the novel compounds. Overall, minimal cross-reactivity was observed, highlighting the conclusion that these presumptive screens cannot detect many of the designer drugs and that a confirmatory technique, such as the LC-MS, is required for the comprehensive forensic toxicological analysis of designer drugs.
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Andrews, Anthony Robert John. „The chemiluminescence detemination of drugs of forensic interest“. Thesis, University of Hull, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306129.

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Lutfi, Layal Anton. „Stability of drugs of forensic interest in post mortem blood“. Thesis, University of Glasgow, 1998. http://theses.gla.ac.uk/7085/.

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The stability study of drugs of forensic interest in human post-mortem blood is an important forensic study, because in some cases, a requirement for the laboratory to undertake a full drug screening is after a few months of storage due to a need for new evidence. Therefore, it is necessary and important to know if drugs are stable over a period of time under different conditions to enable a solid interpretation to be made from any results. Some studies have been published on the stability of drugs at different temperatures but none had covered the whole set of drugs that has been studied in this thesis. The periods of study that have been covered by other studies varied from a few days to a maximum of 70 weeks, but again not all drugs have been covered. The drugs studies in this thesis are two sets of drugs, benzodiazepines and tricyclic antidepressants, their stability being determined over twelve months and at three different temperatures 25,5 and -20°C. In this thesis, blood was 'spiked' with eight drugs, Diazepam, Temazepam, Triazolam, Desmethyldiazepam, Amitriptyline, Nortriptyline, Imipramine and Chlorpromazine. The samples were stored with blanks at different temperatures for different storage times. Each month a number of samples were removed from storage and analysed to test the effect of storage time and temperature on drug concentration. Different solid phase and liquid-liquid extraction methods were tested for the determination of benzodiazepines. Liquid-liquid extraction methods for - 2 - the determination of Diazepam, Temazepam, desmethyldiazepam and Triazolam proved after study to be tedious and time-consuming. A method based on solid phase extraction was used to determine the four benzodiazepine drugs. The extraction method gave good recoveries and was highly efficient. The method of analysis used for the determination of stability of benzodiazepine drugs was the high performance liquid chromatography (HPLC) method. Tricyclic antidepressant drugs are the other drugs studied for their stability in blood. Different solid phase extraction methods were used for the determination of drugs in post-mortem blood but gave poor recoveries. The best method of extraction used was a liquid-liquid extraction method which yielded high recoveries and proved to be quick. The method of analysis used for the determination of tricyclic antidepressants for the purpose of stability of the study was gas chromatography (GC). At a recognised toxic level for each drug under study a reasonable amount of the drug was found to be detectable after one year at storage regardless of the storage temperature or media. The decrease rate of each drug concentration with time at the three storage conditions (25, 5 and -200e) was obtained.
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Alshamaileh, M. Y. „Novel strategies for the analysis of drugs of abuse“. Thesis, University of Lincoln, 2016. http://eprints.lincoln.ac.uk/23695/.

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The data presented in this thesis has been organized in three parts: First part included the development and validation of a quantitative HPLC-DAD analytical method of mephedrone after extraction from spiked whole blood and serum samples, alone and with methcathinone. The second part included in vitro metabolism of mephedrone and other NPS, which are methoxetamine and methcathinone, using an in-house prepared in vitro metabolic system, namely liver microsomes, followed by performing analysis for the drugs and their proposed metabolites utilizing LC-MS. Third part included in vitro studies of selected NPS using purchased HepaRG and hepatocytes. In vitro study included in vitro cytotoxicity studies of 4-fluoromethamphetamine, mephedrone, methoxetamine and methcathinone, and analytical studies of these drugs of abuse and their potentially produced metabolites using GC-MS. In the first part of this thesis, a HPLC method for the analysis of mephedrone after LLE from blood matrix was developed and validated and shown to be linear with R2> 0.995, precise with intraday and interday RSD values of 4.36 and 4.77% respectively and LOD and LOQ of 0.025 and 0.082 μg/mL respectively. Recovery percentages were low and ranged between 28-37%. Emulsion formation was the major problem effaced which negatively affected recovery and precision values. The previously developed method was optimised and fully validated for the simultaneous analysis of mephedrone and methcathinone after liquid-liquid extraction (LLE) from whole blood and serum samples. The LLE method was optimised through selection of extraction solvent and adjustment of pH values achieving the best validation parameters and minimal emulsion formation. The LLE protocol involved extraction with a mixture of dichloromethane: n-butanol (80:20 v: v) after buffering the sample with borate buffer pH=9.2 and using aniline as internal standard. The HPLC-DAD method was optimized, using reverse mode chromatography and buffered mobile phase of (acetate buffer pH 4.1: ACN – 85:15) for qualitative and quantitative analysis of these drugs in less than 10 minutes under isocratic elution and ambient temperature. The method was fully validated for both drugs and showed to be linear over the specified range of 0.1-10 μg/mL with R2 > 0.99 for both drugs. The accuracy was assessed by calculating percentage recovery at different concentrations for xii both drugs, and retained recovery percent between 84-110%. For repeatability and intermediate precision tests, RSD values were ≤ 6.73%. Specificity was assessed by good resolution between the peaks and by checking peak purities. Limit of detection and limit of quantification, calculated mathematically for both drugs either extracted from whole blood or serum samples, were 0.010- 0.013 μg/ml and 0.032 - 0.043 μg/mL, respectively. In the second part, in vitro studies on the metabolism of the selected NPS using pig liver microsomes and liquid chromatography-mass spectrometry (LC-MS) analysis were performed. Microsomes were prepared by a conventional ultracentrifugation method. In brief, pig liver was brought freshly from local abattoir, sliced into small pieces, homogenised and ultra-centrifuged to produce microsomes and S9 fractions. Produced microsomes were incubated with the drugs of interest under optimised conditions and followed by analysis utilizing LC-MS for the detection of the drugs and the potentially produced metabolites. It was possible to detect two metabolites of the drug mephedrone, hydroxytolyl-mephedrone and nor-dihydro mephedrone. For MXE, one metabolite produced by the O-demethylation was detected and it identity confirmed by MS/MS study to be o-desmethyl-MXE. Another metabolite was detected is suggestively produced by the reduction of the ketone moiety to produce dihydro-MXE or by two steps of O-demethylation and hydroxylation to produce O-desmethyl –hydroxy-MXE. However, due to low intensity signal recorded, MS/MS study was not conclusive for the identity of the molecule In the third part, two types of hepatocytes were used for the study of the metabolism and cytotoxicity of the selected NPS - Mephedrone, Methoxetamine, Methcathinone and 4-Fluoromethamphetamine. Studying the metabolism of selected NPS followed utilizing HepaRG™ followed by GC-MS analysis, it was possible to detect new peaks in the chromatograms of mephedrone and methcathinone which is suggestively the product of N-demethylation. However, it was not possible to detect any new peaks in the chromatograms of methoxetamine nor 4-flouromethamphetamine. The cytotoxicity study utilizing HepaRG cell line showed that these drugs have cytotoxic effects causing in vitro cell death, within the specified range of 4.0x10-2-1.6x101 mM. These drugs were able to cause 43-83% ii cell death, and EC50 values were 0.2323-0.6297 mM. The most potent drug was 4-fluoromethamphetamine, while mephedrone showed the least biological effect to produce.
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Björn, Niklas. „Database processing for identification of concomitant drug frequencies in a forensic material positive for antidepressant drugs“. Thesis, Linköpings universitet, Institutionen för medicin och hälsa, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107575.

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This article presents a study conducted on data containing drug concentrations. The data was obtained from femoral venous blood samples collected at medico legal autopsies in Sweden. Cases positive for antidepressant drugs were scrutinized and divided in to two groups for 15 antidepressant drugs: B‑cases, where the cause of death was intoxication with more than one drug detected in the blood sample. C‑cases, where the cause of death was NOT intoxication and at least one drug (the antidepressant) was detected in the blood sample. This data was then processed to find frequencies of concomitant drugs taken together with the antidepressant drugs. Frequencies of the most common concomitant drugs were then compared between B-cases and C-cases for each antidepressant drug. This revealed that the drugs dextropropoxyphene, ethanol, codeine, flunitrazepam, paracetamol, propiomazine and alimemazine were signifcantly more common as concomitant drugs in B-cases (intoxications) than in C‑cases (non‑intoxications). With regards to unknown interactions the most interesting combinations were: Propiomazine with mirtazapine, venlafaxine, citalopram or fluoxetine; Paracetamol with paroxetine; Flunitrazepam with mirtazapine, venlafaxine or citalopram; Codeine with mirtazapine or sertraline. These combinations should be further investigated.
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Ali, Esam M. A. „Applications of Raman Spectroscopic Techniques in Forensic and Security Contexts. The detection of drugs of abuse and explosives in scenarios of forensic and security relevance using benchtop and portable Raman spectroscopic instrumentation“. Thesis, University of Bradford, 2010. http://hdl.handle.net/10454/5267.

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Drug trafficking and smuggling is an ongoing challenge for law enforcement agencies. Cocaine smuggling is a high-value pursuit for smugglers and has been attempted using a variety of concealment methods including the use of bottled liquids, canned milk, wax and suspensions in cans of beer. In particular, traffickers have used clothing impregnated with cocaine for smuggling. Handling, transportation or re-packaging of drugs of abuse and explosives will inevitably leave residual material on the clothing and other possessions of the involved persons. The nails and skin of the person may also be contaminated through the handling of these substances. This research study describes the development of Raman spectroscopic techniques for the detection of drugs of abuse and explosives on biomaterials of forensic relevance including undyed natural and synthetic fibres and dyed textile specimens, nail and skin. Confocal Raman microscopy has been developed and evaluated for the detection and identification of particulates of several drugs of abuse and explosives on different substrates. The results show that excellent spectroscopic discrimination can be achieved between single particles and substrate materials, giving a ubiquitous non-destructive approach to the analysis of pico-gram quantities of the drugs and explosives in-situ. Isolating the particle in this way corresponds with an analytical sensitivity comparable with the most sensitive analytical techniques currently available e.g. the highly sensitive, yet destructive ionization desorption mass spectrometry. With the confocal Raman approach, this work demonstrates that definitive molecular-specific information can be achieved within seconds without significant interference from the substrate. The potential for the application of this technique as a rapid preliminary, forensic screening procedure is obvious and attractive to non-specialist operators as it does not involve prior chemical pretreatment ii or detachment of the analyte from the substrate. As a result, evidential materials can be analysed without compromising their integrity for future investigation. Also, the applications of benchtop and portable Raman spectroscopy for the in-situ detection of drugs of abuse in clothing impregnated with the drugs have been demonstrated. Raman spectra were obtained from a set of undyed natural and synthetic fibres and dyed textiles impregnated with these drugs. The spectra were collected using three Raman spectrometers; one benchtop dispersive spectrometer coupled to a fibre-optic probe and two portable spectrometers. High quality spectra of the drugs could be acquired in-situ within seconds and without any sample preparation or alteration of the evidential material. A field-portable Raman spectrometer is a reliable instrument that can be used by emergency response teams to rapidly identify unknown samples. This method lends itself well to further development for the in-situ examination by law enforcement officers of items associated with users, handlers and suppliers of drugs of abuse in the forensics arena. In the last section of this study, a portable prototype Raman spectrometer ( DeltaNu Advantage 1064) equipped with 1064 nm laser excitation has been evaluated for the analysis of drugs of abuse and explosives. The feasibility of the instrument for the analysis of the samples both as neat materials and whilst contained in plastic and glass containers has been investigated. The advantages, disadvantages and the analytical potential in the forensics arena of this instrument have been discussed.
Egyptian Government and Sohag University
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Ali, Esam Mohamed Abdalla. „Applications of Raman spectroscopic techniques in forensic and security contexts : the detection of drugs of abuse and explosives in scenarios of forensic and security relevance using benchtop and portable Raman spectroscopic instrumentation“. Thesis, University of Bradford, 2010. http://hdl.handle.net/10454/5267.

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Drug trafficking and smuggling is an ongoing challenge for law enforcement agencies. Cocaine smuggling is a high-value pursuit for smugglers and has been attempted using a variety of concealment methods including the use of bottled liquids, canned milk, wax and suspensions in cans of beer. In particular, traffickers have used clothing impregnated with cocaine for smuggling. Handling, transportation or re-packaging of drugs of abuse and explosives will inevitably leave residual material on the clothing and other possessions of the involved persons. The nails and skin of the person may also be contaminated through the handling of these substances. This research study describes the development of Raman spectroscopic techniques for the detection of drugs of abuse and explosives on biomaterials of forensic relevance including undyed natural and synthetic fibres and dyed textile specimens, nail and skin. Confocal Raman microscopy has been developed and evaluated for the detection and identification of particulates of several drugs of abuse and explosives on different substrates. The results show that excellent spectroscopic discrimination can be achieved between single particles and substrate materials, giving a ubiquitous non-destructive approach to the analysis of pico-gram quantities of the drugs and explosives in-situ. Isolating the particle in this way corresponds with an analytical sensitivity comparable with the most sensitive analytical techniques currently available e.g. the highly sensitive, yet destructive ionization desorption mass spectrometry. With the confocal Raman approach, this work demonstrates that definitive molecular-specific information can be achieved within seconds without significant interference from the substrate. The potential for the application of this technique as a rapid preliminary, forensic screening procedure is obvious and attractive to non-specialist operators as it does not involve prior chemical pretreatment ii or detachment of the analyte from the substrate. As a result, evidential materials can be analysed without compromising their integrity for future investigation. Also, the applications of benchtop and portable Raman spectroscopy for the in-situ detection of drugs of abuse in clothing impregnated with the drugs have been demonstrated. Raman spectra were obtained from a set of undyed natural and synthetic fibres and dyed textiles impregnated with these drugs. The spectra were collected using three Raman spectrometers; one benchtop dispersive spectrometer coupled to a fibre-optic probe and two portable spectrometers. High quality spectra of the drugs could be acquired in-situ within seconds and without any sample preparation or alteration of the evidential material. A field-portable Raman spectrometer is a reliable instrument that can be used by emergency response teams to rapidly identify unknown samples. This method lends itself well to further development for the in-situ examination by law enforcement officers of items associated with users, handlers and suppliers of drugs of abuse in the forensics arena. In the last section of this study, a portable prototype Raman spectrometer ( DeltaNu Advantage 1064) equipped with 1064 nm laser excitation has been evaluated for the analysis of drugs of abuse and explosives. The feasibility of the instrument for the analysis of the samples both as neat materials and whilst contained in plastic and glass containers has been investigated. The advantages, disadvantages and the analytical potential in the forensics arena of this instrument have been discussed.
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Morrison, Calum M. „Chiral and achiral analysis of benzodiazepine and anti-anginal drugs in forensic toxicology“. Thesis, University of Glasgow, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321443.

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Westraat, Hendrik. „Pilot study : Investigating the chemical composition of illegal drugs and the associated prevalence of the different drug types in the Bellville and Athlone police districts in the Western Cape, South Africa“. Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20916.

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Very little chemical information is known about substances being abused in South-Africa. This can be attributed to the fact that possession of drugs constitutes a criminal offence. Not much research is done, and with the exception of self-reported, rehabilitation institution data, from the South African Community Epidemiology Network on Drug Use (SACENDU) and the South African Police drug related arrest data, no other data on drugs and drug use, is publically available. Drugs are being manufactured from legal and illegal chemicals in clandestine laboratories, not complying with any health, safety or quality standards causing a serious health risk in communities. The strategy for the fight against drug abuse in South Africa, the National Drug Master Plan 2013-2017 (NDMP), is compiled by the Central Drug Authority (CDA). Without proper research, data to base decisions and strategies on and proper measuring of achievements, the implementation of the plan suffers as a consequence. The Forensic Science Laboratory (FSL) of the South African Police Service (SAPS), is responsible for the chemical testing of substances, suspected of being illegal drugs, for identification purposes. This supports the prosecuting of suspects during criminal procedures. With the active ingredient known, the use of street names e.g. Tik, Choef or Speed (all referring to methamphetamine) can be abandoned and confusion and misconceptions eliminated. This pilot study investigates the arrest data, in combination with the charge laid against the arrestee and the chemically identified active ingredient in each case. Arrest data revealed a 400% increase in drug related arrests over the last 10 years, while the NDMP requires a 10% decrease. It further highlights the fact that the measurement of success (number of arrests) in the SAPS, resulted in a focus on arresting persons in possession of drugs. The dealers and manufacturers were not adequately addressed and prevention, through chemical monitoring, suffered as a result. This study also clearly revealed that international trends are not a definite indication of the extent and type of drug abuse in South African Communities. The study further attempts to contribute, and to better describe the situation of drugs and drug abuse in communities. This in turn, will provide data to develop evidence based strategies, designed to meet the defined needs of communities, one of the aspects highlighted by the minister in the NDMP, namely an intervention based on reality and local statistics. It is therefore clear that a scientific understanding of the composition of abused substances can direct treatment, policy, prevention measures and provide intelligence to combat drug abuse and illegal drug manufacturing in South Africa.
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Al, Najjar Ahmed Omer. „Enhancement of Sensitivity in Capillary Electrophoresis: Forensic and Pharmaceutical Applications“. Ohio University / OhioLINK, 2004. http://www.ohiolink.edu/etd/view.cgi?ohiou1107276943.

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Bücher zum Thema "Forensic Drugs"

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Andrews, Anthony Robert John. The chemiluminescence determination of drugs of forensic interest. [Hull, Eng.]: [s.n.], 1990.

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1962-, Gadzala Daniel E., Hrsg. Handbook of drug analysis: Applications in forensic and clinical laboratories. Washington, DC: American Chemical Society, 1997.

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Brian, Caddy, Hrsg. The analysis of drugs of abuse: An instruction manual. New York: E. Horwood, 1995.

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Wesley, James F. DrugBase: Drug identification database. Rochester, NY: Wesmost Press, 1995.

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Wesley, James F. DrugBase: Drug identification database. Rochester, NY: Wesmont Press, 1995.

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International Symposium on the Forensic Aspects of Controlled Substance (1988 Forensic Science Research and Training Center, FBI Academy). Proceedings of the International Symposium on the Forensic Aspects of Controlled Substances: March 28-April 1, 1988, Forensic Science Research and Training Center, FBI Academy, Quantico, Virginia. Washington, DC: Laboratory Division, Federal Bureau of Investigation, U.S. Dept. of Justice, 1988.

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Parsons, Robert. Protocols for the analysis of solid dose drugs in forensic science. Boca Raton, FL: CRC Press, 2003.

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King, L. A. Forensic chemistry of substance misuse: A guide to drug control. Cambridge, UK: Royal Society of Chemistry, 2009.

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Forensic chemistry of substance misuse: A guide to drug control. Cambridge, UK: Royal Society of Chemistry, 2009.

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King, L. A. Forensic chemistry of substance misuse: A guide to drug control. Cambridge, UK: Royal Society of Chemistry, 2009.

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Buchteile zum Thema "Forensic Drugs"

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Daéid, Niamh Nic. „Drugs of abuse“. In Forensic Chemistry, 1–39. Chichester, UK: John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118897768.ch1.

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Harris, Howard A., und Henry C. Lee. „Drugs and drug analysis“. In Introduction to Forensic Science and Criminalistics, 327–56. Second edition. | Boca Raton, FL : CRC Press, [2019] | Revised edition of : Introduction to forensics & criminalistics / Howard A. Harris, Henry Lee, c2008.: CRC Press, 2019. http://dx.doi.org/10.4324/9781315119175-13.

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Payne-James, Jason, und Richard Jones. „Licit and illicit drugs“. In Simpson's Forensic Medicine, 307–20. 14e. | Boca Raton : CRC Press, 2019. | Preceded by Simpson's forensic medicine / Jason Payne-James … [et al.]. 13th ed. c2011. |: CRC Press, 2019. http://dx.doi.org/10.1201/9781315157054-24.

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Levine, Barry S. „Miscellaneous Therapeutic Drugs“. In Principles of Forensic Toxicology, 523–43. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42917-1_29.

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Byrd, Jason H., und Michelle R. Peace. „Entomotoxicology: Drugs, Toxins, and Insects“. In Forensic Chemistry Handbook, 483–99. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118062241.ch14.

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Apple, Fred S. „Postmortem Redistribution of Drugs“. In Principles of Forensic Toxicology, 595–601. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42917-1_34.

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Spargo, Erin A. „Drugs in Embalmed Tissues“. In Principles of Forensic Toxicology, 665–71. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-42917-1_40.

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8

Parsons, Stanley M. „Date-Rape Drugs with Emphasis on GHB“. In Forensic Chemistry Handbook, 355–434. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118062241.ch11.

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DiMaio, Vincent J. M., und D. Kimberley Molina. „Interpretive Toxicology and Deaths Due to Drugs“. In DiMaio's Forensic Pathology, 469–95. 3. Aufl. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.4324/9780429318764-21.

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Endres, Gregory W., Travis J. Worst und Jon E. Sprague. „Designer Drugs“. In Chromatographic Techniques in the Forensic Analysis of Designer Drugs, 17–28. Boca Raton : Taylor & Francis/CRC Press, 2018. | Series: Chromatographic science series: CRC Press, 2018. http://dx.doi.org/10.1201/9781315313177-2.

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Konferenzberichte zum Thema "Forensic Drugs"

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Kaati, Lisa, Fredrik Johansson und Elinor Forsman. „Semantic technologies for detecting names of new drugs on darknets“. In 2016 IEEE International Conference on Cybercrime and Computer Forensic (ICCCF). IEEE, 2016. http://dx.doi.org/10.1109/icccf.2016.7740426.

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Izham, Andi, und Elza Ibrahim Auerkari. „The use of radiology CBCT in odontology forensic“. In THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0047278.

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Adrianto, Angger Waspodo Dias, Bambang Tri Hartomo, Nurtami Soedarsono und Elza Ibrahim Auerkari. „DNA adducts, genotoxicity mechanism of alkyl compounds in association with forensic dentistry“. In THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5139339.

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Hartomo, Bambang Tri, Nurtami Soedarsono, Angger Waspodo Dias Adrianto und Elza Ibrahim Auerkari. „Review of biomolecular methods for age estimation in application of forensic odontology“. In THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5139364.

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Hartomo, Bambang Tri, Angger Waspodo, Fanni Kusuma Djati und Elza Ibrahim Auerkari. „Review of epigenetics and its relationship to dental anthropology and forensic odontology“. In THE 4TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, HEALTH, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2019. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5139365.

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Romanova, Olga, Dmitry Sundukov, Arkady Golubev und Mikhail Blagonravov. „Forensic evaluation of the rate of development of ARDS in cases of poisoning with clozapine and baclofen“. In Issues of determining the severity of harm caused to human health as a result of the impact of a biological factor. ru: Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/conferencearticle_5fdcb03aabda96.57249908.

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Acute respiratory distress syndrome (ARDS) is a syndrome of severe respiratory failure. Its etiology is associated with the impact of various aggression factors, which can be divided into direct and indirect. The aim of our study was to identify and compare histomorphological changes in the lungs in clozapine (150 mg/kg) and Baclofen (85 mg/kg) administration, depending on the conditions of use of these drugs. Experiments were conducted on outbreed male rats weighing 250–290 g and 20 weeks old. The animals were divided into 5 groups: the controls, Baclofen (85 mg/kg), clozapine (150 mg/kg), Baclofen (85 mg/kg and ethanol), clozapine (150 mg/kg) and ethanol.
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Dawoud, Abdulilah A. „Fabrication of Fully Integrated Microfluidic Device With Carbon Sensing Electrode for the Detection of Forensic and Biomedical Targets“. In ASME 2007 International Mechanical Engineering Congress and Exposition. ASMEDC, 2007. http://dx.doi.org/10.1115/imece2007-41454.

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Fabrication of fully integrated capillary electrophoresis (CE)-based microfluidic device with integrated carbon sensing electrode is described in this paper. A combination of microfabrication protocols were employed for fabricating the hybrid PDMS/glass microfluidic device including chemical wet etching, soft lithography, and micromolding techniques. The microdevice is comprised of glass substrate with integrated gold electrodes and carbon sensing electrode, and polydimethyl siloxane (PDMS) slab that encompasses the microchannels network. The carbon sensing electrode was physically characterized via atomic force microscopy (AFM) and Raman spectrometry. In addition, its quality was evaluated electrochemically and compared to commercial glassy carbon electrodes upon performing cyclic voltammetric analysis of two illicit drugs, morphine and codeine. The analytical performance of the stand-alone microdevice was evaluated upon testing the injection, separation and amperometric detection on the carbon sensing electrode. The carbon sensing electrode provides stable background current during applying high sensing potential, which is of particular necessity for sensing molecules that can be only detected at high potentials including morphine and codeine.
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Mahdy, Tarek, Abdulaziz Al-Sulaiti, Yasser Abdelqader, Abdelrahman Fikry, Gaffar Hag und Mohammad I. Ahmad. „A Validated and Applicable Direct Injection LC/MS/MS Method of Fourteen Drugs of Abuse in Urine Samples to Avoid the False Positive/Negative Results of Immunoassay Techniques in Forensic Cases“. In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0146.

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Many false positive and false negative results have been detected in immunoassay analyses of drugs of abuse in urine samples. A method of direct injection of diluted urine into LC/MS/MS was developed and validated for detection and quantitation of Amphetamine, Methamphetamine, MDMA, MDA, Benzoylecgonine, Ecgonine, Norpseudoephedrine, Ephedrine, Tapentadol, Tramadol, O-desmethyltramadol, Tapentadol, Pregabline, Gabapentine and Methadone to avoid the false positive and false negative results in urine samples. Linearity of Amphetamine, Methamphetamine MDMA, MDA, Benzoylecgonine, Ecgonine, Norpseudoephedrine and Ephedrine was (60-2400ng/mL), for Tapentadol, Tramadol, O-desmethyltramadol, and Methadone was (50-1600 ng/mL), and for Pregabline and Gabapentine was (100-4000ng/mL) and r2 ˃ 0.992 for all analysts. A 440 urine samples have been analyzed using both immunoassay technique and LC/MS/MS by direct injection method giving a good comparison to illustrate how this method was specific, accurate, precise, and applicable for forensic urine samples
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Cieslinski, Benjamin, Mohamed Gharib, Brady Creel und Tala Katbeh. „A Model Science-Based Learning STEM Program“. In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-10352.

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Abstract In this paper, a model STEM program called Engineering Heroes: Qatar Special Investigators (QSI), aimed to familiarize young students with science and engineering in real life applications, is presented. The program theme is about forensic science and technology, which included science and engineering activities with hands-on projects to challenge students’ science and critical thinking skills. Throughout the program, students learned about forensic science as an application of science, engineering and technology to collect, preserve, and analyze evidence to be used in the course of a legal investigation. Participants learned the history of forensic analysis and how it evolved into today’s specialized career field. Forensic specialists include backgrounds in chemistry, physics, biology, toxicology, chemical and electrical engineering. Topics included in the program were a study of toxicology and chemical analysis, assays to determine drug contents, fingerprint development, environmental contamination, chromatography in forgery, presumptive vs. confirmatory testing, scanning electron microscopy, infrared analysis, and evidence handling techniques. The details of the program are presented, including the contents, preparation, materials used, case studies, and final crime scene investigation, which featured the learning outcomes.
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Semenov, Sergey, Alexandr Bozhchenko und Pavel Tolkach. „Iatrogenic death of a patient as a result of local anesthesia with the use of the drug “Naropin”“. In Issues of determining the severity of harm caused to human health as a result of the impact of a biological factor. ru: Publishing Center RIOR, 2020. http://dx.doi.org/10.29039/conferencearticle_5fdcb03ab42468.53224529.

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The article considers the clinical and forensic aspects of the possibility of establishing a causal relationship between the use of the drug “Naropin” and the death of a patient during local anesthesia. In this case, the patient sought outpatient medical care for paraproctitis. The decision made by the doctor the decision for local anesthesia is the use of the drug “Naropin”. At 20 minutes of administration of the drug in the required dosage, the patient suddenly developed convulsions and clinical death occurred, and later the patient died. When conducting a forensic examination of the corpse, the most significant was the following: a small pinpoint wound in the upper quadrant of the right buttock, pulmonary edema, liquid blood and small loose blood clots in the heart cavities, brain edema. During a post-mortem Toxicological examination of the blood, the presence of ropivacaine (a component of naropine) was found to exceed the threshold toxic concentration. Repeated expert research has found that led to the onset of death-the erroneous introduction of the anesthetic “Naropin” directly into the blood vessel, which is prohibited by the instructions for its use due to a very narrow zone of toxic action.
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Berichte der Organisationen zum Thema "Forensic Drugs"

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Norsworthy, Sarah, Rebecca Shute, Crystal M. Daye und Paige Presler-Jur. National Institute of Justice’s Forensic Technology Center of Excellence 2019 National Opioid and Emerging Drug Threats Policy and Practice Forum. Herausgegeben von Jeri D. Ropero-Miller und Hope Smiley-McDonald. RTI Press, Juli 2020. http://dx.doi.org/10.3768/rtipress.2020.cp.0011.2007.

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The National Institute of Justice (NIJ) and its Forensic Technology Center of Excellence (FTCoE) hosted the National Opioid and Emerging Drug Threats Policy and Practice Forum on July 18–19, 2019, in Washington, DC. The forum explored ways in which government agencies and programs, law enforcement officials, forensic laboratory personnel, medical examiners and coroners, researchers, and other experts can cooperate to respond to problems associated with drug abuse and misuse. Panelists from these stakeholder groups discussed ways to address concerns such as rapidly expanding crime laboratory caseloads; workforce shortages and resiliency programs; analytical challenges associated with fentanyl analogs and drug mixtures; laboratory quality control; surveillance systems to inform response; and policy related to stakeholder, research, and resource constraints. The NIJ Policy and Practice Forum built off the momentum of previous stakeholder meetings convened by NIJ and other agencies to discuss the consequences of this national epidemic, including the impact it has had on public safety, public health, and the criminal justice response. The forum discussed topics at a policy level and addressed best practices used across the forensic community.
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Jarron, Matthew, Amy R. Cameron und James Gemmill. Dundee Discoveries Past and Present. University of Dundee, November 2020. http://dx.doi.org/10.20933/100001182.

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A series of self-guided walking tours through pioneering scientific research in medicine, biology, forensics, nursing and dentistry from the past to the present. Dundee is now celebrated internationally for its pioneering work in medical sciences, in particular the University of Dundee’s ground-breaking research into cancer, diabetes, drug development and surgical techniques. But the city has many more amazing stories of innovation and discovery in medicine and biology, past and present, and the three walking tours presented here will introduce you to some of the most extraordinary. Basic information about each topic is presented on this map, but you will ­find more in-depth information, images and videos on the accompanying website at uod.ac.uk/DundeeDiscoveriesMap For younger explorers, we have also included a Scavenger Hunt – look out for the cancer cell symbols on the map and see if you can ­find the various features listed along the way!
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Evaluation of occupational exposures to illicit drugs at forensic sciences laboratories. U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, März 2020. http://dx.doi.org/10.26616/nioshhhe201801163370.

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