Um die anderen Arten von Veröffentlichungen zu diesem Thema anzuzeigen, folgen Sie diesem Link: Fingerprints damages.
Zeitschriftenartikel zum Thema „Fingerprints damages“
Geben Sie eine Quelle nach APA, MLA, Chicago, Harvard und anderen Zitierweisen an
Machen Sie sich mit Top-50 Zeitschriftenartikel für die Forschung zum Thema "Fingerprints damages" bekannt.
Neben jedem Werk im Literaturverzeichnis ist die Option "Zur Bibliographie hinzufügen" verfügbar. Nutzen Sie sie, wird Ihre bibliographische Angabe des gewählten Werkes nach der nötigen Zitierweise (APA, MLA, Harvard, Chicago, Vancouver usw.) automatisch gestaltet.
Sie können auch den vollen Text der wissenschaftlichen Publikation im PDF-Format herunterladen und eine Online-Annotation der Arbeit lesen, wenn die relevanten Parameter in den Metadaten verfügbar sind.
Sehen Sie die Zeitschriftenartikel für verschiedene Spezialgebieten durch und erstellen Sie Ihre Bibliographie auf korrekte Weise.
1
Gaebel, Christoph Michael. „Formability of an Anti-Fingerprint Coating Considering the Corrosion Behavior of the Stainless Steel Substrate“. Advanced Materials Research 769 (September 2013): 189–96. http://dx.doi.org/10.4028/www.scientific.net/amr.769.189.
Der volle Inhalt der QuelleAnnotation:
Ground and satin stainless steel surfaces are often applied to lend various products a characteristic high-quality appearance. Examples can be found in interior and exterior architecture, passenger elevators, public ticket machines and cover panels of white goods. In everyday use the visual appearance of these products is impaired by soiling. Especially on the surfaces of household appliances fingerprints tend to accumulate. On satin stainless steel parts the cutaneous sebum sticks to the brush marks. Thus extensive cleaning effort is required. Since several years the manufacturers of stainless steel offer satin stainless-steel sheet metal equipped with thin clear coatings for this application. The clear coating fills the brush marks and also causes a better wetting behavior and optimal cleaning properties. In this regard, the term easy-to-clean surface is common.The manufacturers face the challenge of applying a very thin clear coating with an index of refraction adjusted to the satin stainless steel surface and the cutaneous sebum. Thus, ideally the coating should not be distinguishable, concerning haptic and optic properties. The thickness of these coatings amounts to a few micrometers. Therefore, the heat transfer coefficient of the surface only varies minimally and the surface does not feel painted. The advantageous wetting behavior and the slightly differing reflection properties of the clear coating contribute to reducing the adhesion and conspicuousness of fingerprints significantly. Because of these attributes the term anti-fingerprint coatings is used.A further prerequisite for the application of anti-fingerprint coatings in high-quality parts is a good scratch resistance. Therefore, nanoparticle-reinforced coating systems are applied. Typically hard particles like SiO2 or Al2O3 are used. In addition to this, a curing procedure by ultraviolet radiation combined with a suitable solvent-free coating system can be used. This further improves the hardness and scratch resistance of the coating. Due to these requirements the clear coatings are applied in a coil-coating procedure. Consequently, the final painted sheets have to be processed to the respective sheet metal part. Common forming processes for white goods’ panels are bending and crash forming. After forming the final processor does not spend any effort on varnishing or curing on-site which leads to special cost savings in comparison to a piecework coating.The required performance characteristics of the anti-fingerprint coating allow no compromises concerning the coating system with regard to the formability. During forming operations damage is caused to the clear coating in the form of crack formation and delamination. Due to the optical properties of coating systems specifically adjusted to ground stainless steel surfaces, the defects in the clear coating are difficult to identify precisely. However, the properties of the final painted sheet metals’ surface are impaired. This also includes the corrosion resistance which must be taken into account especially for stainless steel applications, e.g. in the kitchen area or in outdoor applications.On the one hand this paper deals with experimental analyses for the identification of the defects caused to an anti-fingerprint clear coating by forming operations. The elaborated procedure is used to identify cracks and delamination due to bending operations. In the experiments mandrel bending specimens of the coated stainless steel sheet metal are formed. Due to different bending radii the intensity of cracks and delamination in the coating varies. But the orientation of the bending edge towards the grinding direction also influences the damage intensity and the damage characteristics. These specimens are also examined in a salt spray test to determine the influence of the different coating damages on the corrosion resistance of the stainless steel substrate. In comparison, the same stainless steel sheet metal material without clear coating is tested simultaneously. The comparison demonstrates the influence of the coating and the deformation-induced damages. On the other hand, to examine the damages as a result of a typical forming process a simplified oven panel is manufactured in a crash forming tool. The front side of the panel remains flat and shows no strains. But along the sharp bending radius, which is typical for the design of high-quality white goods’ applications, cracks in the clear coating can be observed. The experimental results show an influence on the coating damages resulting from the use of a deep draw foil. Furthermore, the forming tool features a heating device and panels are formed at higher temperatures with an effect on the coating damages.
2
Gjorgieva, Darinka, Tatjana Kadifkova Panovska, Tatjana Ruskovska, Katerina Bačeva und Trajče Stafilov. „Influence of Heavy Metal Stress on Antioxidant Status and DNA Damage inUrtica dioica“. BioMed Research International 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/276417.
Der volle Inhalt der QuelleAnnotation:
Heavy metals have the potential to interact and induce several stress responses in the plants; thus, effects of heavy metal stress on DNA damages and total antioxidants level inUrtica dioicaleaves and stems were investigated. The samples are sampled from areas with different metal exposition. Metal content was analyzed by Inductively Coupled Plasma-Atomic Emission Spectrometer (ICP-AES), for total antioxidants level assessment the Ferric-Reducing Antioxidant Power (FRAP) assay was used, and genomic DNA isolation from frozen plant samples was performed to obtain DNA fingerprints of investigated plant. It was found that heavy metal contents in stems generally changed synchronously with those in leaves of the plant, and extraneous metals led to imbalance of mineral nutrient elements. DNA damages were investigated by Random Amplified Polymorphic DNA (RAPD) technique, and the results demonstrated that the samples exposed to metals yielded a large number of new fragments (total 12) in comparison with the control sample. This study showed that DNA stability is highly affected by metal pollution which was identified by RAPD markers. Results suggested that heavy metal stress influences antioxidant status and also induces DNA damages inU. dioicawhich may help to understand the mechanisms of metals genotoxicity.
3
Si, Xiuhua April, und Jinxiang Xi. „Deciphering Exhaled Aerosol Fingerprints for Early Diagnosis and Personalized Therapeutics of Obstructive Respiratory Diseases in Small Airways“. Journal of Nanotheranostics 2, Nr. 3 (22.06.2021): 94–117. http://dx.doi.org/10.3390/jnt2030007.
Der volle Inhalt der QuelleAnnotation:
Respiratory diseases often show no apparent symptoms at their early stages and are usually diagnosed when permanent damages have been made to the lungs. A major site of lung pathogenesis is the small airways, which make it highly challenging to detect using current techniques due to the diseases’ location (inaccessibility to biopsy) and size (below normal CT/MRI resolution). In this review, we present a new method for lung disease detection and treatment in small airways based on exhaled aerosols, whose patterns are uniquely related to the health of the lungs. Proof-of-concept studies are first presented in idealized lung geometries. We subsequently describe the recent developments in feature extraction and classification of the exhaled aerosol images to establish the relationship between the images and the underlying airway remodeling. Different feature extraction algorithms (aerosol density, fractal dimension, principal mode analysis, and dynamic mode decomposition) and machine learning approaches (support vector machine, random forest, and convolutional neural network) are elaborated upon. Finally, future studies and frequent questions related to clinical applications of the proposed aerosol breath testing are discussed from the authors’ perspective. The proposed breath testing has clinical advantages over conventional approaches, such as easy-to-perform, non-invasive, providing real-time feedback, and is promising in detecting symptomless lung diseases at early stages.
4
Winda, Tri Wulandari, Ruslan Renggong und Abdul Salam Siku. „FUNGSI SIDIK JARI DALAM PENGUNGKAPAN KASUS TINDAK PIDANA PEMBUNUHAN (Studi Kasus pada Ditreskrimum Polda Sulawesi Selatan)“. Indonesian Journal of Legality of Law 2, Nr. 1 (09.12.2019): 1–5. http://dx.doi.org/10.35965/ijlf.v2i1.140.
Der volle Inhalt der QuelleAnnotation:
The purpose of this study was to find out the Fingerprint Function for investigators in disclosing criminal cases of murder and barriers experienced by investigators in conducting evidence with Fingerprint (Dactyloscopy) at the South Sulawesi Regional Police Regional Police Directorate. This study uses a type of qualitative research, by examining and studying a science of fingerprint identification which is used as the basis for conducting problem solving and qualitative analysis. The results of the research are: fingerprint function for investigators in disclosing criminal cases of murder which states that by identifying or observing fingerprints, one can find out one's identity in detail and clearly because as we know in this world no one has a fingerprint. the same so that the fingerprints possessed by humans are not the same and the obstacles of investigators in conducting evidence with the science of fingerprinting, ie the crime scene is no longer in the status quo or the crime scene is damaged so investigators have difficulty identifying fingerprints. This can be seen by the existence of criminal cases of murder in the South Sulawesi Regional Police Headquarters Ditreskrimum
5
Dewi, Wulan Wiryantari, und Ibrahim R. „Kekuatan Hukum Pelekatan Sidik Jari Penghadap Oleh Notaris Pada Minuta Akta“. Acta Comitas 5, Nr. 3 (14.12.2020): 436. http://dx.doi.org/10.24843/ac.2020.v05.i03.p01.
Der volle Inhalt der QuelleAnnotation:
The notary's role is to provide legal protection to the people who use his services. The presence of a Notary is indispensable for the community concerned to hold a legal relationship with other individuals so that the Notary may also be liable. In the provisions of Article 16 paragraph (1) letter c of the Amendment Law, it is stipulated that in carrying out his position, the Notary is required to attach fingerprints on the minutes of the deed, giving rise to various polemics, because the said provisions do not stipulate further if in this case the smoker suffers from finger defects or events that result in damage to fingerprints which makes the investigator unable to put his fingerprint. The purpose of this research is to find out how the efforts that can be done by a notary against those who are unable to put fingerprints and the legal consequences of the absence of fingerprints against the strength of the deed. This research is a type of normative legal research. The results of this study indicate that efforts can be made by a notary if there are those who suffer from finger defects or experience events that cause fingerprint damage so that they cannot attach their fingerprints to the minutes of the deed, the relevant Notary can explain the matter at the end of the deed. he made it because the fingerprints attached to the address are an act that is required to a notary that can lead to administrative sanctions as contained in the Amendment Law. Due to the legal absence of fingerprints attached to the strength of the deed that is the deed made by the relevant Notary Public remains an authentic deed even though the fingerprints of the tappers are not attached based on Article 1869 of the Civil Code and the deed is valid and legally binding as long as the provisions contained in Article 1320 are fulfilled Civil Code.
6
Ganiyev Otabek, Abdullayev Rustam,. „Digital fingerprinting: New opportunities for solving crimes?“ Psychology and Education Journal 58, Nr. 1 (01.01.2021): 2713–18. http://dx.doi.org/10.17762/pae.v58i1.1154.
Der volle Inhalt der QuelleAnnotation:
High technologies at the present stage of development of the world community have penetrated into all spheres of human activity. Considering the issue of digital methods of crime investigation, of course, forensic experts are faced with problems of their effectiveness. Today, most Western countries in the investigation of crimes use fingerprint examination, using technology, thereby reducing the time of investigation, ensuring efficiency. And yet, not all forensic specialists use these techniques when taking fingerprints, relying on the reliability and the usual proven practice of the classical method of fingerprinting. As you know, in the countries of the post-Soviet space, this method was used on the basis of scientific approaches developed by such scientists as E. Henry, A. Bertillon, G. Gross, E. Locard, etc. For example, the work of E. Henry formed the basis for fingerprint registration, since the scientific approach to the biological process of damage and restoration of the epidermis during the investigation of a crime, it is necessary to attach special importance, since papillary lines also have the property of recoverability. If the dermis is damaged, then the pattern is not restored in such an area. But the scars that appear at the same time, the scars themselves become the hallmarks of the pattern. For a century, forensic scientists have studied the sweat marks of handprints for identification, since each fingerprint is different. In this analytical article, the authors made an attempt to conduct an analytical review of the implementation practices of digital fingerprinting in different countries and study the extent to which the effectiveness of its application is possible.
7
Huang, Rui, und Tingting Tang. „Assembly of Magnetic Nano-Fe3O4@GSH-Au NCs Core–Shell Microspheres for the Visualization of Latent Fingerprints“. Nano 13, Nr. 11 (November 2018): 1850128. http://dx.doi.org/10.1142/s179329201850128x.
Der volle Inhalt der QuelleAnnotation:
Glutathione (GSH), the protective agent and reducing agent, has been widely used to prepare gold nanoclusters (GSH-Au NCs) with stable fluorescence properties and negative charge of the surface. Meanwhile, polyethyleneimine (PEI) was used as the modification agent to synthesize magnetic ferroferric oxide nanoparticles (Fe3O4) with fantastic dispersibility and positive charge of the surface. Based on the electrostatic adsorption force, magnetic nano-Fe3O4@GSH-Au NCs core–shell microspheres composed of magnetic Fe3O4 nanoparticles modified by PEI as the core and GSH-Au NCs as the shell were assembled. The prepared Fe3O4@GSH-Au NCs microspheres harbored a uniform size (88.6[Formula: see text]nm), high magnetization (29.2[Formula: see text]emu/g) and excellent fluorescence. Due to the coordination bond action between Au atom and sulfhydryl (–SH), amino (–NH2), carboxyl (–COOH) in sweat, Fe3O4@GSH-Au NCs could combine with latent fingerprints. In addition, Fe3O4@GSH-Au NCs with good fluorescence and magnetism could detect fingerprints on various objects. Significantly, the powders were not easy to suspend in the air, which avoided the damage to the health of forensic experts and the fingerprints by only powder contacting. Above all, Fe3O4@GSH-Au NCs was successfully applied to the latent fingerprint visualization, which has great potential in forensic science.
8
Hasanah, Uswatun, und Yulia Monita. „Sidik Jari sebagai Pendukung Alat Bukti dalam Proses Penyidikan Perkara Pidana“. PAMPAS: Journal of Criminal Law 1, Nr. 3 (23.04.2021): 139–56. http://dx.doi.org/10.22437/pampas.v1i3.11086.
Der volle Inhalt der QuelleAnnotation:
The purpose of this study was to determine the use of fingerprints to support the process of proving evidence in the investigation of criminal cases in the Jambi Regional Police and to determine the effectiveness of fingerprints as supporting evidence in the investigation of criminal cases. The number of criminal cases that occurred in Jambi made the police improve their performance, one of which was in the investigation process by looking for evidence of evidence, one of which was a fingerprint. The results of this study are the use of fingerprints can support the process of proving evidence in the investigation of criminal cases, because the discovery of fingerprints of someone suspected of committing a crime will make it easier for the police to find other evidence, for in Jambi itself the use of fingerprints as preliminary evidence rarely seen from 2016-2019, there were only 5 cases that used fingerprints as an initial guide, because in Jambi itself still had many shortcomings such as at the time of the crime scene many fingerprints were found but many were already damaged, and many criminal acts were indirectly reported, for its own effectiveness the Jambi Regional Police have very complete and sophisticated equipment such as those at the National Police Headquarters and are very effective in terms of cases and tools that all 5 cases that occurred were effective using fingerprints as evidence for initial instructions. Abstrak Tujuan penelitian ini adalah untuk mengetahui penggunaan sidik jari bisa mendukung proses pembuktian alat bukti dalam proses penyidikan perkara pidana di Polda Jambi serta untuk mengetahui efektivitas sidik jari sebagai pendukung alat bukti dalam proses penyidikan perkara pidana. Banyaknya kasus kejahatan yang terjadi di Jambi membuat pihak kepolisian semakin meningkatkan kinerjanya yang salah satunya ialah dalam proses penyidikan dengan mencari bukti petunjuk yang salah satunya sidik jari. Hasil penelitian ini adalah penggunaan sidik jari bisa mendukung proses pembuktian alat bukti dalam proses penyidikan perkara pidana, karena dengan ditemukannya sidik jari seseorang yang diduga melakukan tindak pidana maka akan memudahkan pihak kepolisian dalam mencari bukti lain, untuk di Jambi sendiri penggunaan sidik jari sebagai bukti awal jarang dilakukan terlihat dari tahun 2016-2019 hanya terdapat 5 kasus yang menggunakan sidik jari sebagai petunjuk awal, karena di Jambi sendiri masih memiliki banyak kekurangan seperti pada saat olah TKP banyak ditemukan sidik jari akan tetapi banyak yang sudah rusak, dan banyak kejadian tindak pidana yang tidak langsung dilaporkan, untuk efektivitasnya sendiri Polda Jambi memiliki peralatan yang sangat lengkap dan canggih sudah seperti di Mabes Polri dan sangat efektif dari segi kasus dan alatnya bahwa dari 5 kasus yang terjadi semuanya efektif dengan menggunakan sidik jari sebagai alat bukti petunjuk awal.
9
Liu, Guo Jun, Yong Qing Yang und Fan Guo. „Research on Identification Theories of Bridge Damage“. Advanced Materials Research 143-144 (Oktober 2010): 614–18. http://dx.doi.org/10.4028/www.scientific.net/amr.143-144.614.
Der volle Inhalt der QuelleAnnotation:
This paper makes a research on dynamic fingerprints methods and model updating methods of identification theories of bridge damage. And it has a full study on and makes a comparison among the four basic theories of dynamic fingerprints and their applications in engineering, signifying the advantages and disadvantages. The general procedures of damage identification of model updating method are proposed. And finally it points out that the problems needing further studies and the directions of development in damage identification theories.
10
Necheporenko, O. „PROBLEMATIC ASPECTS OF SHOEPRINTS SEIZURE FROM THE CRIME SCENE (Review Article)“. Theory and Practice of Forensic Science and Criminalistics 22, Nr. 2 (26.05.2020): 73–81. http://dx.doi.org/10.32353/khrife.2.2020.06.
Der volle Inhalt der QuelleAnnotation:
The author of the article analyzes existing methods of seizing three-dimensional and latent (two-dimensional) shoeprints, described in the forensic scientific literature, which are used in Ukraine and abroad. Attention is drawn to the fact that methods of seizing traces that have been used for a long time are a subject to minor changes, despite the development of scientific and technological progress. The author names a reason for such a phenomenon: the lack of exchange in experience with countries that use modern tools and techniques for forensic analysis, one of which is a crime scene fingerprint film lift pad. The crime scene fingerprint lift pad is most often used when seizing latent (two-dimensional) shoe prints during inspection of a crime scene. However, attention is drawn to the problem of further suitability of seized traces for carrying out forensic examination as well as to peculiarities of storing seized materials.
According to the author, trace damage is associated with two groups of factors: removal of a trace with violation of a technique and removal of a trace by means of poor-quality material. The author describes several types of crime scene fingerprint lift pad which is used to seize evidence of trace evidence nature.
The author notes that along with the development of technology, trace evidence methods should be advanced as well. There is an urgent need to analyze the market of imported fingerprints, its efficiency, specificity of forensic situations, weather conditions, etc. There is also a need to share experiences in the use of such materials by forensic expert subdivisions. The question as to improving domestic production of fingerprint products, increasing the cost for purchasing high-quality materials also arises. Such an approach will fix the situation with quality of a crime scene processing and collection of evidence which will have a positive impact on detection of crimes and identification of perpetrators. The author emphasizes the relevance of this study and need for new theoretical and practical developments.
11
Lee, Gwangrog, Mahir Rabbi, Robert L Clark und Piotr E Marszalek. „Nanomechanical Fingerprints of UV Damage To DNA“. Small 3, Nr. 5 (04.05.2007): 809–13. http://dx.doi.org/10.1002/smll.200600592.
Der volle Inhalt der Quelle
12
Gan, Xin Ji, Yan Chen und Lin Li. „Laser Cleaning of Neutral Attenuator Plate Based on Low Power Laser Diode“. Advanced Materials Research 614-615 (Dezember 2012): 1547–52. http://dx.doi.org/10.4028/www.scientific.net/amr.614-615.1547.
Der volle Inhalt der QuelleAnnotation:
Laser cleaning is a non-contact, green and environmental cleaning method, which can effectively remove particulate contaminations of sizes as small as 0.1 μm without damage to the optics. But most laser cleaning devices are large and heavy, also expensive due to using large lasers such as CO2 laser, YAG Laser etc. In this work a low power LD was tried to clean fingerprint and dust contaminated on the surface of the attenuator glasses plates. In the laser cleaning experiment with low power diode the fingerprint grease can be efficient to be cleaned, but there is no evident effect for cleaning inorganic dust. The cleaning different degree of fingerprint contaminations was investigated at the variable laser parameters, including laser power and irradiation time. An optical microscope was used to analyze the cleaning effect. The results show that low power LD can effectively remove the fingerprint on the surface of absorptive-type attenuator glass plates. On the premise that the attenuator optics glasses are not damaged, the cleaning area increases with the increase of radiation time and laser power. The cleaning area doesn't change much with the variation of laser frequency when the other parameters are the same.
13
Su, Zhongqing, und Lin Ye. „Digital Damage Fingerprints (DDF) and its application in quantitative damage identification“. Composite Structures 67, Nr. 2 (Februar 2005): 197–204. http://dx.doi.org/10.1016/j.compstruct.2004.09.033.
Der volle Inhalt der Quelle
14
Saitoh, Naoki, und Norimitsu Akiba. „Ultraviolet Fluorescence Imaging of Fingerprints“. Scientific World JOURNAL 6 (2006): 691–99. http://dx.doi.org/10.1100/tsw.2006.143.
Der volle Inhalt der QuelleAnnotation:
We studied fluorescence imaging of fingerprints on a high-grade white paper in the deep ultraviolet (UV) region with a nanosecond-pulsed Nd-YAG laser system that consists of a tunable laser and a cooled CCD camera.Clear fluorescence images were obtained by time-resolved imaging with a 255- to 425-nm band-pass filter, which cuts off strong fluorescence of papers. Although fluorescence can be imaged with any excitation wavelength between 220 and 290 nm, 230 and 280 nm are the best in terms of image quality. However, the damage due to laser illumination was smaller for 266-nm excitation than 230- or 280-nm excitation.Absorption images of latent fingerprints on a high-grade white paper are also obtained with our imaging system using 215- to 280-nm laser light. Shorter wavelengths produce better images and the best image was obtained with 215 nm. Absorption images are also degraded slightly by laser illumination, but their damage is smaller than that of fluorescence images.
15
Eckersley, Alexander, Matiss Ozols, Ronan O'Cualain, Emma-Jayne Keevill, April Foster, Suzanne Pilkington, David Knight, Christopher E. M. Griffiths, Rachel E. B. Watson und Michael J. Sherratt. „Proteomic fingerprints of damage in extracellular matrix assemblies“. Matrix Biology Plus 5 (Februar 2020): 100027. http://dx.doi.org/10.1016/j.mbplus.2020.100027.
Der volle Inhalt der Quelle
16
Tang, Kai, Aijia Liu, Wei Wang, Pengfei Li und Xi Chen. „A Novel Fingerprint Sensing Technology Based on Electrostatic Imaging“. Sensors 18, Nr. 9 (12.09.2018): 3050. http://dx.doi.org/10.3390/s18093050.
Der volle Inhalt der QuelleAnnotation:
In this paper, we propose a new fingerprint sensing technology based on electrostatic imaging, which can greatly improve fingerprint sensing distance. This can solve the problem of the existing capacitive fingerprint identification device being easy to damage due to limited detection distance and a protective coating that is too thin. The fingerprint recognition sensor can also be placed under a glass screen to meet the needs of the full screen design of the mobile phone. In this paper, the electric field distribution around the fingerprint is analyzed. The electrostatic imaging sensor design is carried out based on the electrostatic detection principle and MEMS (micro-electro-mechanical system) technology. The MEMS electrostatic imaging array, analog, and digital signal processing circuit structure are designed. Simulation and testing are carried out as well. According to the simulation and prototype test device test results, it is confirmed that our proposed electrostatic imaging-based fingerprint sensing technology can increase fingerprint recognition distance by 46% compared to the existing capacitive fingerprint sensing technology. A distance of more than 439 μm is reached.
17
Wang, Junwen, Dan Luo, Ming Liang, Ting Zhang, Xiquan Yin, Ying Zhang, Xiangliang Yang und Wei Liu. „Spectrum-Effect Relationships between High-Performance Liquid Chromatography (HPLC) Fingerprints and the Antioxidant and Anti-Inflammatory Activities of Collagen Peptides“. Molecules 23, Nr. 12 (10.12.2018): 3257. http://dx.doi.org/10.3390/molecules23123257.
Der volle Inhalt der QuelleAnnotation:
A total of 13 batches of collagen peptide samples were extracted, isolated, and purified from chicken sternal cartilage under various process parameters. The fingerprint profiles of 13 batches of collagen peptides were established by high-performance liquid chromatography (HPLC). In addition, the amino acid profiles and molecular weight distributions of collagen peptides were investigated. The in vitro antioxidant activities of the peptide samples were measured using the 2,2′-Azinobis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) assay, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, the ferric-reducing antioxidant power (FRAP) assay and an assay of the oxidative damage induced by hydrogen peroxide (H2O2) in the degenerative cartilage cells from the knee joint of rat C518 (C518 cell line). The anti-inflammatory activities of the peptide samples were assessed by measuring the inflammatory responses induced by lipopolysaccharides (LPS) in C518 cells. Subsequently, the spectrum-effect relationships between HPLC fingerprints and the antioxidant and anti-inflammatory activities of collagen peptides were investigated using grey relational analysis (GRA). Fifteen common peaks were obtained from the HPLC fingerprints of collagen peptides. Each collagen peptide sample had a characteristic set of amino acid types and contents. All of the hydrolysates of the collagen peptides were primarily composed of fractions II (500–1000 Da) and III (1000–3000 Da). Collagen peptides exhibited good scavenging activity on ABTS radical, DPPH radical, and ferric-reducing antioxidant power. Collagen peptides were also effective against H2O2-induced cellular oxidative damage in C518 cells. The antioxidant activity of collagen peptides was due to the low molecular weight and the presence of antioxidant and hydrophobic amino acid residues within its sequence. Collagen peptides significantly inhibited the secretion of inflammatory cytokines IL-1β, TNF-α, and PGE2 in C518 cells. The anti-inflammatory activity of collagen peptides may include increased synthesis of the key components of extracellular matrix (ECM) and inhibited apoptosis of chondrocytes. The GRA results showed that peaks 2, 3, and 8 were the main components contributing to the antioxidant activity of the collagen peptides, whereas peaks 11 and 14 were the main components contributing to the anti-inflammatory activity of the collagen peptides. The components of peaks 8 and 14 were identified as GPRGPPGPVGP and VAIQAVLSLYASGR by UPLC-MS/MS. Those identified collagen peptides offer a potential therapeutic strategy for the treatment of osteoarthritis (OA) due to their antioxidative stress and due to them disturbing the catabolism and anabolism processes in arthrodial cartilage.
18
Hsieh, Shu-Feng, Dhimiter Bello, Daniel F. Schmidt, Anoop K. Pal und Eugene J. Rogers. „Biological oxidative damage by carbon nanotubes: Fingerprint or footprint?“ Nanotoxicology 6, Nr. 1 (18.02.2011): 61–76. http://dx.doi.org/10.3109/17435390.2011.553689.
Der volle Inhalt der Quelle
19
Barotova, Stepanka, Martin Drahansky und Radim Pernicky. „Detection of Ridge Damages in Fingerprint Recognition Caused by Skin Diseases“. International Journal of Signal Processing, Image Processing and Pattern Recognition 9, Nr. 11 (30.11.2016): 125–46. http://dx.doi.org/10.14257/ijsip.2016.9.11.13.
Der volle Inhalt der Quelle
20
Perner, Marcus, Maik Müller, Michael Sinapius und Helmut Beikirch. „An Approach for Autonomous Damage Detection by Means of Modal Fingerprints“. Journal of Intelligent Material Systems and Structures 22, Nr. 1 (21.12.2010): 93–100. http://dx.doi.org/10.1177/1045389x10390252.
Der volle Inhalt der Quelle
21
Zaidi, SHH. „Dermatoglyphics: A Brief Review“. International Journal of Advanced and Integrated Medical Sciences 1, Nr. 3 (2016): 111–15. http://dx.doi.org/10.5005/jp-journals-10050-10039.
Der volle Inhalt der QuelleAnnotation:
ABSTRACT Dermatoglyphics refers to epidermal ridges present on the palm, sole, fingers, and toes. These epidermal ridges are formed in the same intrauterine period when neuronal development takes place in the intrauterine life of a fetus. Thus, dermatoglyphics is correlated with genetic abnormalities and is useful in the diagnosis of congenital malformations and many other medical disorders. Each and every individual has unique fingerprints, even in twins. These fingerprints remain the same lifelong from their development unless they are damaged by dermal injuries. The different regions of our brain are reflected by fingerprints, palm prints and foot patterns present in the 10 fingers, 10 toes, palmar and plantar surfaces respectively and these dermatoglyphics represent the various regions of brain therefore can be used in dermatoglyphics mental intelligence test (DMIT) and now a day is being used globally. How to cite this article Singh A, Gupta R, Zaidi SHH, Singh A. Dermatoglyphics: A Brief Review. Int J Adv Integ Med Sci 2016;1(3):111-115.
22
Cetin-Atalay, Rengul, und Mehmet Ozturk. „p53 mutations as fingerprints of environmental carcinogens“. Pure and Applied Chemistry 72, Nr. 6 (01.01.2000): 995–99. http://dx.doi.org/10.1351/pac200072060995.
Der volle Inhalt der QuelleAnnotation:
Mutations of the p53 tumor suppressor gene occur in a great majority of human cancers. The protein product of p53 gene is involved in DNA damage response. Consequently, p53 gene may be a preferred target for environmental carcinogens, which also act as DNA-damaging agents. This is probably why p53 mutations are frequent in cancers linked to environmental carcinogens. Moreover, these carcinogens leave molecular fingerprints on the p53 gene. Thus, the study of p53 mutation spectra has been a useful approach to implicate suspected carcinogens to different human cancers. This review provides further insight into the significance of p53 mutation spectra in ten common human malignancies (skin, liver, lung, bladder, breast, head and neck, esophagus, stomach and colorectal cancers, and hematological malignancies), in relation with environmental carcinogens.
23
Wang, Xin, und Wei Bing Hu. „Structural Health Monitoring for Steel Structures“. Applied Mechanics and Materials 351-352 (August 2013): 1088–91. http://dx.doi.org/10.4028/www.scientific.net/amm.351-352.1088.
Der volle Inhalt der QuelleAnnotation:
The process of implementing a damage identification strategy for aerospace, civil and mechanical engineering infrastructure is referred to as structural health monitoring. Many different types and degrees accidents take place, especially some important collapse accidents, the significance of steel structural health monitoring has been recognized. The introduction begins with a brief research status of steel structural health monitoring in china and the world. The paper analyzes the projects and contents of steel structures monitoring from nine aspects and summarizes the diagnosis methods of steel structural damages which include power fingerprint analysis, the methods of model correction and system identification, neural network methods, genetic algorithm and wavelet analysis, it provides us theoretical guidence. In conclusion, structural health monitoring for steel structures could reduce the impact of such disasters immediately after natural hazards and man-made disasters both economically and socially, thus it is becoming increasingly important.
24
Sauer, H., R. Brydson, W. Engel und P. N. Rowley. „Coordination “Fingerprints” of Boron Measured by EELS“. Proceedings, annual meeting, Electron Microscopy Society of America 48, Nr. 2 (12.08.1990): 54–55. http://dx.doi.org/10.1017/s0424820100133862.
Der volle Inhalt der QuelleAnnotation:
The electron energy-loss near-edge structure (ELNES) associated with a core-loss edge measured using electron energy-loss spectroscopy (EELS) provides, in favourable cases, a “fingerprint” corresponding to the specific nearest-neighbour coordination of the excited atom.Boron atoms in boron-oxygen compounds occur in both trigonal (BO3) and tetrahedral (BO4) coordinations. The B K-ELNES of BO3 and BO4 units (Figs, le and 2b) are remarkably different and arise from the differing local symmetries which determine the final state molecular orbitals. The BK-ELNES of BO3 units exhibit a sharp π∗ peak at ca. 194 eV followed by a broader σ∗ peak some 9-10 eV higher in energy, which may possess a low energy shoulder. BO4 B K-ELNES show no π∗ peak and display solely a σ∗ peak at ca. 199 eV together with a high energy shoulder. Both these spectra may be modelled using multiple scattering calculations.The mineral howlite contains both BO3 and BO4 units and is sensitive to electron-beaminduced damage.
25
Windham, Mark T., und Robert N. Trigiano. „Are ‘Barton’ and ‘Cloud 9’ the Same Cultivar of Cornus florida L.?“ Journal of Environmental Horticulture 16, Nr. 3 (01.09.1998): 163–66. http://dx.doi.org/10.24266/0738-2898-16.3.163.
Der volle Inhalt der QuelleAnnotation:
Abstract Ten flowering dogwood (Cornus florida) cultivars were evaluated for phenotypic characters including resistance to spot anthracnose and dogwood canker, susceptibility to frost damage, leaf color, bract length and color, bloom number and reproductive phenology. Cultivars differed by at least three phenotypic characters except for ‘Barton’ and ‘Cloud 9’, which when compared with each other, were not significantly different at any characteristic. DNA amplification fingerprinting (DAF) using 17 octamer oligonucleotide primers could not distinguish these cultivars. Furthermore, arbitrary signatures from amplification profiles (ASAP), a technique that produces ‘fingerprints of fingerprints’, which is capable of detecting more differences than DAF, also failed to reveal any polymorphic DNA. Therefore, based on the lack of phenotypic and genetic differences between these two cultivars, we conclude that they are the same genotype.
26
Inggarsih, Rara, Akhyar Dyni Zakyah, Lusia Hayati, Joko Marwoto, Septi Purnamasari, Arwan Bin Laeto und Masayu Farah Diba. „Dermatoglyphy in Breast Cancer Patients: A Systematic Review“. Bioscientia Medicina : Journal of Biomedicine and Translational Research 5, Nr. 4 (23.06.2021): 925–40. http://dx.doi.org/10.32539/bsm.v5i4.368.
Der volle Inhalt der QuelleAnnotation:
Background. Breast cancer is one of the four types of cancer among women and is the most frequently diagnosed in most countries. Breast cancer occurs due to DNA damage and genetic mutations affected by exposure to estrogen, inheritance of damaged DNA, or pro-cancer genes such as BRCA1 and BRCA2. Therefore, a family history of ovarian cancer or breast cancer increases the risk of developing breast cancer. The embryo of the breast develops around the age of 6 weeks of pregnancy. Similar to breast development, fingerprint patterns also develop during the 6-13 weeks of pregnancy. Thus, the genetic message contained in the genome occurred during that period and was reflected in the dermatoglyphic pattern.Methods. The literature search was systematically used using PubMed, Cochran, Google scholar, and other Gray literature between 2010-2020. Of the 69 publications identified, 21 met the criteria and were included in the review. The review is carried out following the provisions of PRISMA (Preferred Reporting Items for Systematic Review).Results. This systematic review showed fairly consistent findings in breast cancer patients who tended to have more whorl fingerprint patterns and larger ATD angles. For radial loops, ulnar loops and arches were minor compared to the control group potential as an initial screening tool in at-risk groups.Conclusion. Long-term and follow-up studies with larger sample sizes in various ethnicities are needed to validate dermatoglyphics in anthropometric measurements as a promising marker of breast cancer.
27
Papanikolaou, Stefanos. „Microstructural inelastic fingerprints and data-rich predictions of plasticity and damage in solids“. Computational Mechanics 66, Nr. 1 (22.04.2020): 141–54. http://dx.doi.org/10.1007/s00466-020-01845-x.
Der volle Inhalt der Quelle
28
Hulme, Mike. „Attributing weather extremes to ‘climate change’“. Progress in Physical Geography: Earth and Environment 38, Nr. 4 (05.06.2014): 499–511. http://dx.doi.org/10.1177/0309133314538644.
Der volle Inhalt der QuelleAnnotation:
Over the last 30 years, scientific research has increasingly implicated human activities in contemporary regional- to global-scale climatic change. Over the last decade, this research has extended to the detection of the fingerprint of human activities on individual extreme weather events. Is it possible to say that this or that weather extreme was ‘caused by’ human activities? Pursuing answers to this question raises many difficult philosophical, epistemological and political issues. In this progress report, I survey the nascent science of extreme weather event attribution by examining the field in four stages: motivations for extreme weather attribution, methods of attribution, some example case studies and the politics of weather event attribution. There remain outstanding political dangers and obstacles for extreme weather attribution if it is to be used, as some claim it can and should be, for guiding climate adaptation investments, for servicing the putative loss and damage agenda of the UN Framework Convention on Climate Change or for underpinning legal claims for liability for damages caused by extreme weather.
29
Yang, Xinfeng, Qiping Hu und Shuaihao Li. „Recognition and classification of damaged fingerprint based on deep learning fuzzy theory“. Journal of Intelligent & Fuzzy Systems 38, Nr. 4 (30.04.2020): 3529–37. http://dx.doi.org/10.3233/jifs-179575.
Der volle Inhalt der Quelle
30
Dong Wang, Lin Ye und Ye Lu. „A Probabilistic Diagnostic Algorithm for Identification of Multiple Notches Using Digital Damage Fingerprints (DDFs)“. Journal of Intelligent Material Systems and Structures 20, Nr. 12 (04.06.2009): 1439–50. http://dx.doi.org/10.1177/1045389x09338323.
Der volle Inhalt der Quelle
31
Bobev, S. G., K. Van Poucke und M. Maes. „First Report of Phytophthora citricola on Cornus mas in Bulgaria“. Plant Disease 93, Nr. 5 (Mai 2009): 551. http://dx.doi.org/10.1094/pdis-93-5-0551a.
Der volle Inhalt der QuelleAnnotation:
Cornelian cherry dogwood (Cornus mas) is a widespread species in Bulgaria and some cultivars with large fruits are the subject of propagation. In the springs of 2007 and 2008, severe, unusual damages were observed on sporadically scattered plantlets of ‘Kazanlashki’ (known also as ‘Kazanlaker’) in a nursery located near Vratza in northwestern Bulgaria. Symptoms were identical in both years and expressed on the leaves, young shoots, and adjacent rootstock wood. Dark brown, necrotic leaf spots initiated most often from the leaf periphery and quickly covered more than half of the leaf area. Necrosis of the leaves and shoots spread toward the older woody tissues and the plantlets died within a couple of weeks. Isolations from symptomatic leaves, shoots, and rootstocks (three to five samples per plant organ) on potato dextrose agar always revealed a fungus-like organism that formed relatively fast-growing white, radial, petaloid colonies. Numerous, ovoid to obpyriform, noncaducous, semipapillate sporangia occasionally with two papilla were observed after 1 or 2 days of incubation at 20°C in nonsterile soil extract (1). Average sporangium size was 39 (35 to 45) × 31 (20 to 35) μm with a ratio between both parameters of approximately 1.26. The pathogen's paragynous antheridia and smooth-walled spherical oogonia (20 to 32 μm in diameter) yielded spherical aplerotic to almost plerotic oospores on V8 medium with an average size of 25 μm. The morphological data identified the organism as Phytophthora citricola (1). Isolates had identical cultural and morphological characteristics, and pathogenicity was tested by laboratory inoculations carried out in 2007 (two isolates) and twice in 2008 (three isolates). Separately, detached leaves of C. mas seedlings and ‘Kazanlashki’ were wiped with 70% ethanol, punctured with a needle, and the wounds inoculated with 5-mm mycelial plugs from a 7-day-old V8 growth plate. Sterile V8 plugs were placed onto similar wounds of control leaves. Leaf samples were incubated at 20°C in a humidified chamber. Necrosis similar to that observed in the field became visible around the mycelia plugs 4 days after inoculation. The necrotic lesions enlarged to 20 to 25 mm in diameter within the next 2 days, whereas the control leaves did not show any symptoms. Subsequently, the pathogen was reisolated solely from all the mycelium-inoculated samples. By means of the same inoculation method, pathogenicity was also demonstrated on shoots and mature fruits of C. mas. DNA was isolated from mycelium of an isolate and the internal transcribed spacer (ITS) region was amplified using ITS6 and ITS4 primers. The PCR product was sequenced (GenBank Accession No. FJ269034) and the BLAST search showed 100% homology with P. citricola, type II (2). To our knowledge, this is the first report of P. citricola on C. mas in Bulgaria, thus confirming its ability to attack Cornus spp. (3). Taking the lethal results of the disease and the polyphagous nature of the causal agent into consideration, this report is a serious warning for nurserymen and consumers. References: (1) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996. (2) M. E. Gallegly and C. X. Hong. Phytophthora: Identifying Species by Morphology and DNA Fingerprints. The American Phytopathological Society, St. Paul, MN, 2008. (3) F. N. Martin and P. W. Tooley. Mycologia 95:269, 2003.
32
Hovakimyan, Anna Sedrak, Siranush Gegham Sargsyan und Arshak Nazaryan. „Self-Organizing Map Application for Iris Recognition“. Journal of Communications and Computer Engineering 3, Nr. 2 (01.03.2014): 10. http://dx.doi.org/10.20454/jcce.2013.760.
Der volle Inhalt der QuelleAnnotation:
Human iris is a good subject of biometrical identification, since iris patterns are unique like fingerprints. Iris is well protected against damage, unlike fingerprints, which can be harder to recognize after years of certain types of manual labor.A problem of iris recognition is considered in the paper. In machine learning, pattern recognition is the assignment of a label to a given input value. Pattern classification is an example of pattern recognition: it attempts to assign each input value to one of a given set of classes. Nowadays various techniques are used for this purpose, and in particular artificial neural networks.For iris recognition problem solving Kohenen Self Organizing Maps are suggested to use. The software for iris recognition is developed which is customizable and allows to select the appropriate parameters of the neural network to obtain the most satisfactory results. The developed Self-Organizing Map Library of classes can be used for various kinds of object classification problem solving as well as for any problems suitable to solve with Self-Organizing Maps.
33
Sekulska-Nalewajko, Joanna, Jarosław Gocławski und Dominik Sankowski. „The Detection of Internal Fingerprint Image Using Optical Coherence Tomography“. Image Processing & Communications 22, Nr. 4 (01.12.2017): 59–72. http://dx.doi.org/10.1515/ipc-2017-0022.
Der volle Inhalt der QuelleAnnotation:
Abstract Recently, optical coherence tomography (OCT) has been tested as a contactless technique helpful for damaged or spoofed fingerprint recovery. Three dimensional OCT images cover the range from the skin surface to papillary region in upper dermis. The proposed method extracts from cross-sections of volumetric images (B-scans) high intensity ridges in both air-epidermis and dermis-epidermis interfaces. The extraction is based on the localisation of two OCT signal peaks corresponding to these edges. The borders are spline smoothed in two orthogonal planes of the image space. The result images are presented and compared with camera views.
34
Pan, Nan, Zhongqing Su, Lin Ye, Li-Min Zhou und Ye Lu. „A quantitative identification approach for delamination in laminated composite beams using digital damage fingerprints (DDFs)“. Composite Structures 75, Nr. 1-4 (September 2006): 559–70. http://dx.doi.org/10.1016/j.compstruct.2006.04.078.
Der volle Inhalt der Quelle
35
Pantelias, Antonio, Demetre Zafiropoulos, Roberto Cherubini, Lucia Sarchiapone, Viviana De Nadal, Gabriel E. Pantelias, Alexandros G. Georgakilas und Georgia I. Terzoudi. „Interphase Cytogenetic Analysis of G0 Lymphocytes Exposed to α-Particles, C-Ions, and Protons Reveals their Enhanced Effectiveness for Localized Chromosome Shattering—A Critical Risk for Chromothripsis“. Cancers 12, Nr. 9 (19.08.2020): 2336. http://dx.doi.org/10.3390/cancers12092336.
Der volle Inhalt der QuelleAnnotation:
For precision cancer radiotherapy, high linear energy transfer (LET) particle irradiation offers a substantial advantage over photon-based irradiation. In contrast to the sparse deposition of low-density energy by χ- or γ-rays, particle irradiation causes focal DNA damage through high-density energy deposition along the particle tracks. This is characterized by the formation of multiple damage sites, comprising localized clustered patterns of DNA single- and double-strand breaks as well as base damage. These clustered DNA lesions are key determinants of the enhanced relative biological effectiveness (RBE) of energetic nuclei. However, the search for a fingerprint of particle exposure remains open, while the mechanisms underlying the induction of chromothripsis-like chromosomal rearrangements by high-LET radiation (resembling chromothripsis in tumors) await to be elucidated. In this work, we investigate the transformation of clustered DNA lesions into chromosome fragmentation, as indicated by the induction and post-irradiation repair of chromosomal damage under the dynamics of premature chromosome condensation in G0 human lymphocytes. Specifically, this study provides, for the first time, experimental evidence that particle irradiation induces localized shattering of targeted chromosome domains. Yields of chromosome fragments and shattered domains are compared with those generated by γ-rays; and the RBE values obtained are up to 28.6 for α-particles (92 keV/μm), 10.5 for C-ions (295 keV/μm), and 4.9 for protons (28.5 keV/μm). Furthermore, we test the hypothesis that particle radiation-induced persistent clustered DNA lesions and chromatin decompaction at damage sites evolve into localized chromosome shattering by subsequent chromatin condensation in a single catastrophic event—posing a critical risk for random rejoining, chromothripsis, and carcinogenesis. Consistent with this hypothesis, our results highlight the potential use of shattered chromosome domains as a fingerprint of high-LET exposure, while conforming to the new model we propose for the mechanistic origin of chromothripsis-like rearrangements.
36
Sun, Shuang, Li Liang, Ming Li und Xin Li. „Multidamage Detection of Bridges Using Rough Set Theory and Naive-Bayes Classifier“. Mathematical Problems in Engineering 2018 (27.05.2018): 1–13. http://dx.doi.org/10.1155/2018/6752456.
Der volle Inhalt der QuelleAnnotation:
This paper is intended to introduce a two-stage detection method to solve the multidamage problem in bridges. Vibration analysis is conducted to acquire the dynamic fingerprints which are regarded as information sources. Bayesian fusion is used to integrate these sources and preliminarily locate the damage. Then, the RSNB method which combines rough set theory and Naive-Bayes classifier is proposed to simplify the sample dimensions and fuse the remaining attributes for damage extent detection. A numerical simulation of a real structure, the Sishui Bridge in Shenyang, China, is conducted to validate the effectiveness of the proposed detection method. Data fusion based method is compared with single-valued index method at the damage localization stage. The proposed RSNB method is compared with the Back Propagation Neural Network (BPNN) method at the damage qualification stage. The results show that the proposed two-stage damage detection method has better performances in regard to transparency, accuracy, efficiency, noise robustness, and stability. Furthermore, an ambient excitation modal test was carried out on the bridge to obtain the vibration responses and assess the damage condition with the proposed method. This novel approach is applicable for early damage detection and provides a basis for bridge management and maintenance.
37
Willis, A. J., und L. Myers. „A cost-effective fingerprint recognition system for use with low-quality prints and damaged fingertips“. Pattern Recognition 34, Nr. 2 (Februar 2001): 255–70. http://dx.doi.org/10.1016/s0031-3203(00)00003-0.
Der volle Inhalt der Quelle
38
Yarana, Chontida, Dustin Carroll, Luksana Chaiswing, Yanming Zhao, Teresa Noel, Michael Alstotte, Jing Chen et al. „Alteration of Circulating Extracellular Vesicle Protein Contents Is a Fingerprint of Chemotherapy-Induced Tissue Damage“. Free Radical Biology and Medicine 100 (November 2016): S195. http://dx.doi.org/10.1016/j.freeradbiomed.2016.10.533.
Der volle Inhalt der Quelle
39
Boot, Maikel, Susanna Commandeur, Amit K. Subudhi, Meriem Bahira, Trever C. Smith, Abdallah M. Abdallah, Mae van Gemert et al. „Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action“. Antimicrobial Agents and Chemotherapy 62, Nr. 7 (16.04.2018): e00083-18. http://dx.doi.org/10.1128/aac.00083-18.
Der volle Inhalt der QuelleAnnotation:
ABSTRACT Due to the rise of drug-resistant forms of tuberculosis, there is an urgent need for novel antibiotics to effectively combat these cases and shorten treatment regimens. Recently, drug screens using whole-cell analyses have been shown to be successful. However, current high-throughput screens focus mostly on stricto sensu life/death screening that give little qualitative information. In doing so, promising compound scaffolds or nonoptimized compounds that fail to reach inhibitory concentrations are missed. To accelerate early tuberculosis (TB) drug discovery, we performed RNA sequencing on Mycobacterium tuberculosis and Mycobacterium marinum to map the stress responses that follow upon exposure to subinhibitory concentrations of antibiotics with known targets, ciprofloxacin, ethambutol, isoniazid, streptomycin, and rifampin. The resulting data set comprises the first overview of transcriptional stress responses of mycobacteria to different antibiotics. We show that antibiotics can be distinguished based on their specific transcriptional stress fingerprint. Notably, this fingerprint was more distinctive in M. marinum. We decided to use this to our advantage and continue with this model organism. A selection of diverse antibiotic stress genes was used to construct stress reporters. In total, three functional reporters were constructed to respond to DNA damage, cell wall damage, and ribosomal inhibition. Subsequently, these reporter strains were used to screen a small anti-TB compound library to predict the mode of action. In doing so, we identified the putative modes of action for three novel compounds, which confirms the utility of our approach.
40
M., Sucharita, Poorani B. und Priya Swaminathan. „An in silico Workflow that Yields Experimentally Comparable Inhibitors for Human Dihydroorotate Dehydrogenase“. Current Computer-Aided Drug Design 16, Nr. 3 (02.06.2020): 340–50. http://dx.doi.org/10.2174/1573409915666190528114703.
Der volle Inhalt der QuelleAnnotation:
Introduction: Rheumatoid Arthritis [RA] is an autoimmune disease that can cause chronic inflammation of the joints. Human DiHydroOrotate DeHydrogenase [DHODH] is a clinically validated drug target for the treatment of Rheumatoid Arthritis. DHODH inhibition results in beneficial immunosuppressant and anti-proliferative effects. Materials and Methods: Leflunomide [LEF] and Brequinar Sodium [BREQ], drugs used in the treatment of RA, suppresses the immune cells responsible for inflammation but has several side-effects, most predominant being symptomatic liver damage and toxicity. An existing scaffold based on structural analogies with LEF and BREQ was used to screen out potent inhibitors of DHODH, in ZINC Database using 2D binary fingerprint. 10 structures similar to the scaffold were shortlisted due to their Tanimoto similarity coefficient. Selected structures were docked using the tools AutoDock, Ligand fit and iGEMDOCK with target human DHODH. High scoring compounds having similar interactions as that of scaffold were checked to evaluate their Drug-Likeliness. Results: The five shortlisted compounds were then subjected to Molecular Dynamics Simulation studies for 50ns using GROMACS. Measures of structural similarity based on 2D Fingerprint Screening and Molecular Dynamics Simulation studies can suggest good leads for drug designing. The novelty of this study is that the workflow used here yields the same results that are at par with the experimental data. Conclusion: This suggests the use of the 2D fingerprint similarity search in various databases, followed by multiple docking algorithms and dynamics as a workflow that will lead to finding novel compounds that a structurally and functionally similar to LEF and BREQ.
41
Zhang, Houquan, Hao Shi, Yu Wu und Hai Pu. „Numerical statistical analysis on self-organizing behavior of microfracturing events in rock failure“. International Journal of Distributed Sensor Networks 14, Nr. 4 (April 2018): 155014771876899. http://dx.doi.org/10.1177/1550147718768993.
Der volle Inhalt der QuelleAnnotation:
Current experimental investigations on microfracturing (or acoustic emission) events mainly focus on their location and distribution. A new function in rock failure process analysis (RFPA2D) code was developed to capture the size and number of damage element groups in each loading step. The rock failure process evolving from the initiation, propagation, and nucleation of microcracks was visually simulated by RFPA2D in this research. Based on the newly developed function, the statistical quantitative analysis of microfracturing events in rock was effectively conducted. The results show that microfracturing (failed element) events in the whole failure process accord with negative power law distribution, showing fractal features. When approaching a self-organized criticality state, the power exponent does not vary drastically, which ranges around 1.5 approximately. The power exponent decreases correspondingly as the stress increases. Through the analysis of the frequency and size of damaged element groups by rescaled range analysis method, the time series of microfracturing events exhibits the self-similar scale-invariant properties. Through the analysis by the correlation function method, the absolute value of the self-correlation coefficient of microfracturing sequence demonstrates a subsequent precursory increase after a long time delay, exhibiting long-range correlation characteristics. These fractal configuration and long-range correlations are two fingerprints of self-organized criticality, which indicates the occurrence of self-organized criticality in rock failure. Compared with the limited in situ monitoring data, this simulation can supply more sufficient information for the prediction of unstable failure and good understanding of the failure mechanism.
42
Kowalczyk, Paweł, Jarosław M. Cieśla, Murat Saparbaev, Jacques Laval und Barbara Tudek. „Sequence-specific p53 gene damage by chloroacetaldehyde and its repair kinetics in Escherichia coli.“ Acta Biochimica Polonica 53, Nr. 2 (03.04.2006): 337–47. http://dx.doi.org/10.18388/abp.2006_3347.
Der volle Inhalt der QuelleAnnotation:
Oxidative stress and certain environmental carcinogens, e.g. vinyl chloride and its metabolite chloroacetaldehyde (CAA), introduce promutagenic exocyclic adducts into DNA, among them 1,N(6)-ethenoadenine (epsilonA), 3,N(4)-ethenocytosine (epsilonC) and N(2),3-ethenoguanine (epsilonG). We studied sequence-specific interaction of the vinyl-chloride metabolite CAA with human p53 gene exons 5-8, using DNA Polymerase Fingerprint Analysis (DPFA), and identified sites of the highest sensitivity. CAA-induced DNA damage was more extensive in p53 regions which revealed secondary structure perturbations, and were localized in regions of mutation hot-spots. These perturbations inhibited DNA synthesis on undamaged template. We also studied the repair kinetics of CAA-induced DNA lesions in E. coli at nucleotide resolution level. A plasmid bearing full length cDNA of human p53 gene was modified in vitro with 360 mM CAA and transformed into E. coli DH5alpha strain, in which the adaptive response system had been induced by MMS treatment before the cells were made competent. Following transformation, plasmids were re-isolated from transformed cultures 35, 40, 50 min and 1-24 h after transformation, and further subjected to LM-PCR, using ANPG, MUG and Fpg glycosylases to identify the sites of DNA damage. In adaptive response-induced E. coli cells the majority of DNA lesions recognized by ANPG glycosylase were removed from plasmid DNA within 35 min, while MUG glycosylase excised base modifications only within 50 min, both in a sequence-dependent manner. In non-adapted cells resolution of plasmid topological forms was perturbed, suggesting inhibition of one or more bacterial topoisomerases by unrepaired epsilon-adducts. We also observed delayed consequences of DNA modification with CAA, manifesting as secondary DNA breaks, which appeared 3 h after transformation of damaged DNA into E. coli, and were repaired after 24 h.
43
Horsman, Graeme, Helen Page und Peter Beveridge. „A preliminary assessment of latent fingerprint evidence damage on mobile device screens caused by digital forensic extractions“. Digital Investigation 27 (Dezember 2018): 47–56. http://dx.doi.org/10.1016/j.diin.2018.10.002.
Der volle Inhalt der Quelle
44
Baptista, Anderson Barbosa, Mariáurea M. Sarandy, Reggiani Vilela Gonçalves, Rômulo Dias Novaes, Cláudio Gonçalves da Costa, João Paulo Viana Leite und Maria do Carmo Gouveia Peluzio. „Antioxidant and Anti-Inflammatory Effects of Anacardium occidentale L. and Anacardium microcarpum D. Extracts on the Liver of IL-10 Knockout Mice“. Evidence-Based Complementary and Alternative Medicine 2020 (07.12.2020): 1–13. http://dx.doi.org/10.1155/2020/3054521.
Der volle Inhalt der QuelleAnnotation:
Background. The Anacardium occidentale L. (cashew) and Anacardium microcarpum D. (cajuí) are plants commonly found in Brazil. They present phytochemical compounds with antioxidant and anti-inflammatory action. Therefore, the objective of this study was to analyze the antioxidant and anti-inflammatory activities of ethanolic extracts from leaves of A. occidentale and A. microcarpum and its effect on the hepatic tissue in experimental knockout models after they received Paracetamol®. Methods. Ethanol extracts from A. occidentale and A. microcarpum leaves were prepared. Total phenolics were determined by Folin–Ciocalteau reagent, and flavonoids are based on the complexation reaction with the aluminum metal, forming a colored complex. Fingerprint HPLC was performed to detect phenolic compounds. Knockout IL-10 mice randomly divided into six groups were used and received the following treatments: G1, only water; G2, A. occidentale extract; G3, A. microcarpum extract; G4, Paracetamol®; G5, Paracetamol® + A. occidentale extract (400 mg/kg); G6, Paracetamol® + A. microcarpum extract (400 mg/kg). Biochemical parameters of the blood and differential count of leukocytes were done. Oxidative markers and histopathological analyses were performed on their liver tissue. Results. Phenolic compounds and total flavonoids were detected in both two extracts analyzed. The HPLC fingerprint detected phenolic acid, gallic acid, and catechin flavonoid in the two extracts. Histopathological analyses of the hepatic tissue permitted evaluation of nuclear increase, sinusoid congestion, and inflammatory infiltrate. A. microcarpum presented more antioxidant activity increasing antioxidant enzyme levels and reducing TBARS and carbonyl protein when compared to the other treatments after exposure to Paracetamol®. Histopathological analyses showed a decrease in the inflammatory infiltrate after treatment with extracts. Conclusion. Our findings indicate that both extracts, especially A. microcarpum, can reduce hepatic damage in knockout mice exposed to paracetamol, indicating the curative power of these extracts reducing lipid peroxidation and in the morphofunctional damage to the liver parenchyma.
45
Yang, Jin, Yongfeng Tang, Huabin He und Shangjun Fu. „Repair of soft tissue defects of the fingers with medial plantar venous flap“. Revista da Associação Médica Brasileira 64, Nr. 6 (Juni 2018): 501–8. http://dx.doi.org/10.1590/1806-9282.64.06.501.
Der volle Inhalt der QuelleAnnotation:
SUMMARY OBJECTIVE To report the surgical procedures and efficacy of using medial plantar venous flap for the repair of soft tissue defects of the fingers. Methods From March 2010 to April 2012, medial plantar venous flaps were harvested to repair the wounds of 31 fingers in 29 cases. Among them, there were 13 middle fingers with defects at the tips in 11 cases, 7 fingers with defects in the dorsal part in 7 cases, and 11 fingers with defects in the finger pulp in 11 cases. The size of the defects ranged from 1.2cm×1.5 cm to 2.5cm × 3.5cm. Medial plantar venous flaps of 1.5cm × 2cm – 3×4 cm were harvested. Full-thickness skin grafts were adopted for the donor areas. RESULTS All 31 flaps survived, except for 1 flap with arterial crisis and 2 cases with venous crisis. These conditions were timely corrected by secondary anastomosis of artery and vein and the flaps survived. The wounds and the donor areas achieved healing by the first intention. All grafted skins survived. Postoperative follow-up was conducted for 26 fingers in 24 cases for 4-12 months, excluding 5 cases with lost follow-up. The dorsal part of the damaged fingers had normal morphology, and the skin color and texture were similar to those of the normal skin. After the repair of defects in the fingertip and pulp, fingerprints appeared, and the protective sensation was restored. CONCLUSION The soft tissue defects of the fingers can be satisfactorily repaired with medial plantar venous flap, and little damage is caused to the donor area. This method is proven effective for the repair of soft tissue defects of the fingers.
46
Pratiwi, Kurniasih Yuni, Suprihatin Suprihatin und Pitoyo Widhi Atmoko. „Pengembangan Sistem RFID dan Fingerprint Terintegrasi dengan Sistem Otomasi Layanan di Perpustakaan Universitas Brawijaya“. Jurnal Pustaka Ilmiah 6, Nr. 1 (20.08.2020): 963. http://dx.doi.org/10.20961/jpi.v6i1.37882.
Der volle Inhalt der QuelleAnnotation:
<p>The guest book used at Brawijaya University is digital, where visitor data is stored in a MySQL database. The use of barcode systems is quite effective compared to manual books that are manual, however, the barcode is printed, so that if too often affected by friction, the barcode can be damaged, to overcome the weaknesses that are owned by the barcode, the use of RFID technology can be a new alternative , because RFID (tag) is a technology in the form of an embedded chip. This research methodology discusses the framework carried out in the development of RFID and Fingerprint as an alternative to library guest book registration.</p><p>In the implementation of NodeMCU and fingerprint sensor to the library guest book database with VB.Net GUI, it can be implemented well. Data filling on RFID cards can be done on data blocks, ie blocks other than trailer blocks and manufacturer blocks. Recording in the library guest book database can be done by comparing the registration time of students, if students register on the same day, then recording is only done once, ie at the beginning of registration. Recording can be done using queries directly embedded in the GUI, or calling functions / procedures stored in the database.</p>
47
Arribas, R., G. Capellà, S. Tórtola, L. Masramon, W. E. Grizzle, M. Perucho und M. A. Peinado. „Assessment of genomic damage in colorectal cancer by DNA fingerprinting: prognostic applications.“ Journal of Clinical Oncology 15, Nr. 10 (Oktober 1997): 3230–40. http://dx.doi.org/10.1200/jco.1997.15.10.3230.
Der volle Inhalt der QuelleAnnotation:
PURPOSE Here we evaluate the prognostic significance of the relative value of genomic damage assessed by DNA fingerprinting in colorectal cancer. MATERIALS AND METHODS Sixty-three tumor and paired normal mucosa samples were included in the study. Genomic damage was assessed by comparative analysis of paired normal and tumor tissue DNA fingerprints by the arbitrarily primed polymerase chain reaction (AP-PCR). Decreases and increases of intensity in bands were computed and referred to the total number of visualized bands per case. An index reflecting the genomic damage fraction (GDF), with separated values for losses and gains, was obtained for each tumor. This index was used to determine molecular and clinicopathologic correlates after exclusion of eight cases displaying microsatellite instability. RESULTS Fifty-five cases were considered for the statistical analysis. The average fraction of altered bands per tumor was 0.287+/-0.121. When losses and gains were computed separately, the average fraction of changes was 0.126+/-0.113 and 0.161+/-0.120, respectively. Tumors lacking a ras mutation showed an increased GDF, primarily because of a higher fraction of gains. Tumors that were at advanced Dukes' stages and that were poorly differentiated also displayed a higher GDF. Finally, disease-free survival was significantly diminished in tumors with a GDF greater than 0.314 (P < .001). The prognostic significance of the GDF was independent of Dukes' stage (Cox multivariate analysis, P = .005). CONCLUSION The degree of genomic damage assessed by unbiased DNA fingerprinting correlates with genotypic, phenotypic, and clinical variables in colorectal carcinoma and may be useful in assessing prognosis in colorectal cancer.
48
Lee, Mijeong, Yujin Choi, Eunah Joo, Jeonghyun Park, Daejoong Kim und Kyung-moo Yang. „Identification on the Cause of Skin Damage through the Application of 1,2-Indanedione reagent as Developing Agent of Latent Fingerprints“. Korean Academy of Scientific Criminal Investigation 13, Nr. 3 (30.09.2019): 198–202. http://dx.doi.org/10.20297/jsci.2019.13.3.198.
Der volle Inhalt der Quelle
49
Lubberts, S., H. Boer, R. Altena, C. Meijer, A. M. van Roon, N. Zwart, S. F. Oosting et al. „Vascular fingerprint and vascular damage markers associated with vascular events in testicular cancer patients during and after chemotherapy“. European Journal of Cancer 63 (August 2016): 180–88. http://dx.doi.org/10.1016/j.ejca.2016.05.022.
Der volle Inhalt der Quelle
50
Demertzi, A., E. Tagliazucchi, S. Dehaene, G. Deco, P. Barttfeld, F. Raimondo, C. Martial et al. „Human consciousness is supported by dynamic complex patterns of brain signal coordination“. Science Advances 5, Nr. 2 (Februar 2019): eaat7603. http://dx.doi.org/10.1126/sciadv.aat7603.
Der volle Inhalt der QuelleAnnotation:
Adopting the framework of brain dynamics as a cornerstone of human consciousness, we determined whether dynamic signal coordination provides specific and generalizable patterns pertaining to conscious and unconscious states after brain damage. A dynamic pattern of coordinated and anticoordinated functional magnetic resonance imaging signals characterized healthy individuals and minimally conscious patients. The brains of unresponsive patients showed primarily a pattern of low interareal phase coherence mainly mediated by structural connectivity, and had smaller chances to transition between patterns. The complex pattern was further corroborated in patients with covert cognition, who could perform neuroimaging mental imagery tasks, validating this pattern’s implication in consciousness. Anesthesia increased the probability of the less complex pattern to equal levels, validating its implication in unconsciousness. Our results establish that consciousness rests on the brain’s ability to sustain rich brain dynamics and pave the way for determining specific and generalizable fingerprints of conscious and unconscious states.