Zeitschriftenartikel: „Externé osi“

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Hehanussa, Patmawaty, Muhammad Kasnir und Danial Danial. „ANALISIS MODEL PENGEMBANGAN PULAU OSI DI KABUPATEN SERAM BAGIAN BARAT SEBAGAI KAWASAN WISATA BAHARI BERKELANJUTAN“. JOURNAL OF INDONESIAN TROPICAL FISHERIES (JOINT-FISH) : Jurnal Akuakultur, Teknologi Dan Manajemen Perikanan Tangkap, Ilmu Kelautan 3, Nr. 1 (28.06.2020): 113–23. http://dx.doi.org/10.33096/joint-fish.v3i1.70.

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This study aims (1) to analyze the relationship between external and internal factors on the sustainability of the marine tourism of Osi Island and (2) formulate a model for the development of marine tourism in Osi Island. This type of research is quantitative descriptive research. Data sources are tourists who are and have been to Osi Island. Techniques used in data collection include field studies / observations and literature studies. Data analysis was performed using a strucktural equation model (SEM) analysis with AMOS analysis tools. The results showed that: (1) Variable internal and external factors significantly influence the sustainability of tourism on Osi Island where human resources are more dominant to contribute to this due to community awareness in the local village in terms of maintaining cleanliness and managing existing nature. Based on this it can be said that in terms of environmental aspects the marine tourism area of Osi Island has fulfilled what is said to be sustainable. (2) the final model of this research is interpreted for the future development plan of Osi Island where the development plan must be based on the vision of sustainable tourism and because Osi Island is a self-managed tourism area, it can develop a community-based tourism model with all stakeholders related namely the central government, local government, etc. can participate in the development both directly and indirectly so that the impact of the development of the model results in an independent community from all aspects.

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Darpeix, Aurélie. „Flexibilité interne et flexibilité externe dans le contrat OMI“. Études rurales, Nr. 182 (01.07.2008): 69–86. http://dx.doi.org/10.4000/etudesrurales.8777.

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Arnold, Neil S., Tjeerd H. van Andel und Vidar Valen. „Extent and Dynamics of the Scandinavian Ice Sheet during Oxygen Isotope Stage 3 (65,000–25,000 yr B.P.)“. Quaternary Research 57, Nr. 1 (Januar 2002): 38–48. http://dx.doi.org/10.1006/qres.2001.2298.

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AbstractThe climate of the middle Weichselian Glaciation, Marine Oxygen Isotope Stage 3 (OIS-3), a relatively mild period compared to the glacial maxima of OIS-4 and OIS-2, consisted of long warm interstades punctuated by brief cold excursions that grew colder and more frequent with time. The OIS-4 ice sheet is generally thought to have persisted throughout OIS-3, but evidence from dated OIS-3 interstadial deposits suggests that it was swiftly reduced to small remnants which only briefly expanded and retreated. Only 30,000 years ago the deteriorating climate initiated a sustained ice advance leading toward the final glacial maximum of OIS-2. Dynamic ice-sheet models support the existence of a prolonged ice-free interval during OIS-3 induced, perhaps, by low precipitation due to extensive sea-ice cover offshore.

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Du, Jianhang, Guangyao Wu, Bokai Wu, Chang Liu, Zhouming Mai, Yumeng Liu, Yawei Wang, Pandeng Zhang, Guifu Wu und Jia Liu. „The Hemodynamic Effect of Enhanced External Counterpulsation Treatment on Atherosclerotic Plaque in the Carotid Artery: A Framework of Patient-Specific Computational Fluid Dynamics Analysis“. Cardiology Research and Practice 2020 (30.04.2020): 1–12. http://dx.doi.org/10.1155/2020/5903790.

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Long-term enhanced external counterpulsation (EECP) therapy has been recommended for antiatherogenesis in recent clinical observations and trials. However, the precise mechanism underlying the benefits has not been fully clarified. To quantify the effect of EECP intervention on arterial hemodynamic environment, a framework of numerical assessment was introduced using a parallel computing algorithm. A 3D endothelial surface of the carotid artery with mild atherosclerotic plaque was constructed from images of magnetic resonance angiography (MRA). Physiologic boundary conditions were derived from images of the ultrasound flow velocity spectrum measured at the common carotid artery and before and during EECP intervention. Hemodynamic factors relating to wall shear stress (WSS) and its spatial and temporal fluctuations were calculated and analyzed, which included AWSS, OSI, and AWSSG. Measuring and computational results showed that diastole blood pressure, perfusion, and WSS level in carotid bifurcation were significantly increased during EECP intervention. Mean AWSS level throughout the model increased by 16.9%, while OSI level did not show a significant change during EECP. We thus suggested that long-term EECP treatment might inhibit the initiation and development of atherosclerotic plaque via improving the hemodynamic environment in the carotid artery. Meanwhile, EECP performance induced a 19.6% increase in AWSSG level, and whether it would influence the endothelial functions may need a further study. Moreover, the numerical method proposed in this study was expected to be useful for the instant assessment of clinical application of EECP .

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Li, Zhongyou, Wentao Jiang, Stephen Salerno, Yi Li, Yu Chen, Zhi Xu und Guanshi Wang. „Acute Hemodynamic Improvement by Thermal Vasodilation inside the Abdominal and Iliac Arterial Segments of Young Sedentary Individuals“. Journal of Vascular Research 58, Nr. 3 (2021): 191–206. http://dx.doi.org/10.1159/000514588.

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Objective: To study the hemodynamic response to lower leg heating intervention (LLHI) inside the abdominal and iliac arterial segments (AIAS) of young sedentary individuals. Methods: A Doppler measurement of blood flow was conducted for 5 young sedentary adults with LLHI. Heating durations of 0, 20, and 40 min were considered. A lumped parameter model (LPM) was used to ascertain the hemodynamic mechanism. The hemodynamics were determined via numerical approaches. Results: Ultrasonography revealed that the blood flow waveform shifted upwards under LLHI; in particular, the mean flow increased significantly (p < 0.05) with increasing heating duration. The LPM showed that its mechanism depends on the reduction in afterload resistance, not on the inertia of blood flow and arterial compliance. The time-averaged wall shear stress, time-averaged production rate of nitric oxide, and helicity in the external iliac arteries increased more significantly than in other segments as the heating duration increased, while the oscillation shear index (OSI) and relative residence time (RRT) in the AIAS declined with increasing heating duration. There was a more obvious helicity response in the bilateral external iliac arteries than the OSI and RRT responses. Conclusion: LLHI can effectively induce a positive hemodynamic environment in the AIAS of young sedentary individuals.

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Su, Xiao Juan, Lingyi Huang, Yi Qu und Dezhi Mu. „Progress in research on the role of Omi/HtrA2 in neurological diseases“. Reviews in the Neurosciences 30, Nr. 3 (24.04.2019): 279–87. http://dx.doi.org/10.1515/revneuro-2018-0004.

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Abstract Omi/HtrA2 is a serine protease present in the mitochondrial space. When stimulated by external signals, HtrA2 is released into the mitochondrial matrix where it regulates cell death through its interaction with apoptotic and autophagic signaling pathways. Omi/HtrA2 is closely related to the pathogenesis of neurological diseases, such as neurodegeneration and hypoxic ischemic brain damage. Here, we summarize the biological characteristics of Omi/HtrA2 and its role in neurological diseases, which will provide new hints in developing Omi/HtrA2 as a therapeutic target for neurological diseases.

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Chan, Samuel KL, Kieran R. Bentick, Jan H. Kuiper und Cormac P. Kelly. „External rotation bracing for first-time anterior dislocation of the shoulder: A discontinued randomised controlled trial comparing external rotation bracing with conventional sling“. Shoulder & Elbow 11, Nr. 4 (26.04.2018): 256–64. http://dx.doi.org/10.1177/1758573218768521.

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IntroductionItoi et al. introduced the concept of bracing in abduction and external rotation to treat traumatic anterior shoulder dislocations. However, controversy remains as studies have reported variable results. Our study investigates whether there is a difference in outcomes between treatment with a conventional sling or external rotation brace.MethodsA prospective, multi-centre randomised control trial was conducted between 2006 and 2010. The study was discontinued early with 72 (36 cases in each group) first-time anterior shoulder dislocations recruited.ResultsThe re-dislocation rate over 24 months was comparable 30% (95% CI: 17–47) sling vs. 24% (95% CI: 13–41) external rotation bracing. Sixteen percent (95% CI: 7–32) of sling patients and 12% (95% CI: 5–27) of external rotation-bracing patients had shoulder stabilisation surgery within 24 months of the initial dislocation (p > 0.05). There was no difference in OSI scores at 24 months between the two treatment groups and intolerability of the external rotation brace was high.ConclusionRecruitment to this study was difficult, and lost-to-follow-up rates were high leading to early discontinuation of the study. The results suggest that ER bracing is unlikely to provide clinical benefit in traumatic first-time anterior shoulder dislocation.

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Llaveria, David, Juan Francesc Munoz-Martin, Christoph Herbert, Miriam Pablos, Hyuk Park und Adriano Camps. „Sea Ice Concentration and Sea Ice Extent Mapping with L-Band Microwave Radiometry and GNSS-R Data from the FFSCat Mission Using Neural Networks“. Remote Sensing 13, Nr. 6 (17.03.2021): 1139. http://dx.doi.org/10.3390/rs13061139.

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CubeSat-based Earth Observation missions have emerged in recent times, achieving scientifically valuable data at a moderate cost. FSSCat is a two 6U CubeSats mission, winner of the ESA S3 challenge and overall winner of the 2017 Copernicus Masters Competition, that was launched in September 2020. The first satellite, 3Cat-5/A, carries the FMPL-2 instrument, an L-band microwave radiometer and a GNSS-Reflectometer. This work presents a neural network approach for retrieving sea ice concentration and sea ice extent maps on the Arctic and the Antarctic oceans using FMPL-2 data. The results from the first months of operations are presented and analyzed, and the quality of the retrieved maps is assessed by comparing them with other existing sea ice concentration maps. As compared to OSI SAF products, the overall accuracy for the sea ice extent maps is greater than 97% using MWR data, and up to 99% when using combined GNSS-R and MWR data. In the case of Sea ice concentration, the absolute errors are lower than 5%, with MWR and lower than 3% combining it with the GNSS-R. The total extent area computed using this methodology is close, with 2.5% difference, to those computed by other well consolidated algorithms, such as OSI SAF or NSIDC. The approach presented for estimating sea ice extent and concentration maps is a cost-effective alternative, and using a constellation of CubeSats, it can be further improved.

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Gogulescu, B. „OS7-53 Multiplanar external fixation in tibia open fractures (by using a couple of external fixators)“. Injury 47 (Oktober 2016): S21. http://dx.doi.org/10.1016/s0020-1383(16)30539-3.

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Koczewski, Pawel, und Milud Shadi. „Korekcje zniekształceń kończyn dolnych u chorych z dysplazjami kostnymi z zastosowaniem stabilizatorów zewnętrznych / Lower limb deformities treatment with external fixators in patients with bone dysplasias“. Advances in Rehabilitation 25, Nr. 1 (01.03.2011): 5–9. http://dx.doi.org/10.2478/rehab-2013-0001.

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Streszczenie Wprowadzenie. Dysplazje kostne jest to niejednorodna grupa schorzeń cechujących się biochemicznymi. mikro- i makroskopowymi zaburzeniami struktury szkieletu prowadzącymi do dysproporcji budowy ciała, nierówności kończyn oraz wielopłaszczyznowych deformacji osiowych. Szczególne miejsce w leczeniu tych deformacji ma metoda dystrakcyjna Ilizarowa. Cel pracy. Celem badań jest ocena wyników leczenia deformacji kończyn dolnych w prze- biegu dysplazji kostnych z zastosowaniem stabilizatorów zewnętrznych. Materiał i metody. Analizie poddano 25 chorych z różnego typu dysplazjami kostnymi (cho- roba Olliera - 10. choroba Blounta - 7. krzywica witamino-D oporna - 2. zespół Elis van Creveld - 2 oraz inne dysplazje - 4). u których leczono 45 segmentów (30 goleni. 15 ud). Wiek chorych w chwili leczenia wahał się od 7 do 20 lat (średnia 13.5). Wskazaniem do leczenie było skłócenie segmentu w 31 przypadkach oraz zagięcie osi w 39 przypadkach. Średnia wartość kąta deformacji wynosiła 18° (od 8 do 43). Chorych podzielono na dwie grupy etiologiczne: 1. z chorobą Olliera i 2. z innymi dysplazjami. Wyniki. Pełną korekcję osi uzyskano we wszystkich korygowanych segmentach. W obrębie skłóconych segmentów uzyskano wydłużenie od 3.0 do 9cm (średnia 5.4). Indeks wydłużenia wahał się od 1.0 do 2.2 mies/cm (średnia 1.43). przy czym w grupie 1. był istotnie mniejszy i wynosił 1.28 podczas gdy w grupie 2. - 1.68. Wnioski. Metoda dystrakcyjna Ilizarowa jest bezpieczną i efektywną metodą korekcji deformacji kończyn dolnych w przebiegu dysplazji kostnych ze stosunkowo niskim odsetkiem powikłań. Pozwala ona na korekcję wielopoziomowych deformacji w sposób jednoczasowy. U chorych z chorobą Olliera indeks wydłużenia jest niższy niż u chorych z innymi typami dysplazji.

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Leblanc, D., J. P. Denhez und H. E. Audier. „Gas-Phase Reaction of Acetaldehyde with Silicon-Containing Ions“. European Journal of Mass Spectrometry 7, Nr. 4-5 (August 2001): 343–49. http://dx.doi.org/10.1255/ejms.444.

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CH2=Si(CH3)OSi(CH3)2+ ions 1 were formed in the external source of a Fourier-transform ion cyclotron resonance (FT-ICR)mass spectrometer by fragmentation of (CH)3SiOSi(CH3)3. In the cell, their reactions with acetaldehyde were studied by using labeled reactants and compared with those with acetone, studied in previous work, which gives a general view of the reactions of ion 1 with carbonyl compounds. In contrast with the behavior of the corresponding carbon-containing ions, the results confirm facile 1,3-methyl group transfers from silicon to silicon. Otherwise, the silicon-containing adducts often eliminate C nH2 n. This process, not observed in (C,O,H)-containing ions, is studied by using selectively deuterated reactants.

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Heldmann, Patrick, Thomas Schöttker-Königer und Axel Schäfer. „Cross-cultural Adaption and Validity of the “Patient Specific Functional Scale” / Kulturelle Adaption und Validierung der deutschen Version der “Patient Specific Functional Scale”“. International Journal of Health Professions 2, Nr. 1 (01.06.2015): 73–82. http://dx.doi.org/10.1515/ijhp-2015-0002.

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Abstract Objective: Measurement of activity and participation related outcomes play an important role in rehabilitation of low back pain. Therefore the „Patient Specific Functional Scale»(PSFS) was developed to assess individual, patient related activities. The aim of this study is the cultural adaptation and validation of the PSFS for German speaking countries.Method: A cultural translation and adaptation process was carried out in accordance with standardized guidelines. The internal and external responsiveness and the construct validity adjustment to the German version pertaining to patients with lumbar back pain was examined in comparison to the «Oswestry Disability Index»(ODI).Results: In both groups the PSFS proved itself to be more sensitive in comparison to the ODI. The internal responsiveness of ODI improved ES= -0.75), (non-improved ES= -0.38). PSFS (improved ES= 1.96), (non-improved ES 0.77). The external responsiveness of ODI (AUC= 0.59), of PSFS (AUC= 0.83) (P= 0.0068). Constructs of both measurement instruments have a weak and a moderate correlation on measuring point 1 (r= -0.28) and 2 (r= -0.58).Conclusion: The German version of PSFS proves itself to be a feasible model and a method of high sensitivity in evaluating changes in the functional ability of patients with lumbar back pain. The instrument can be recommended to be used in clinical practice.

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Werner, David A. T., Margreth Grotle, Sasha Gulati, Ivar M. Austevoll, Mattis A. Madsbu, Greger Lønne und Tore K. Solberg. „Can a Successful Outcome After Surgery for Lumbar Disc Herniation Be Defined by the Oswestry Disability Index Raw Score?“ Global Spine Journal 10, Nr. 1 (06.06.2019): 47–54. http://dx.doi.org/10.1177/2192568219851480.

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Study Design: Prospective multicenter cohort study. Objective: To investigate (1) the discriminative ability and cutoff estimates for success 12 months after surgery for lumbar disc herniation on the Oswestry Disability Index (ODI) raw score compared with a change and a percentage change score and (2) to what extent these clinical outcomes depend on the baseline disability. Methods: A total of 6840 patients operated for lumbar disc herniation from the Norwegian Registry for Spine Surgery (NORspine) were included. In receiver operating characteristic (ROC) curve analyses, a global perceived effect (GPE) scale (1-7) was used an external anchor. Success was defined as categories 1-2, “completely recovered” and “much better.” Cutoffs for success for subgroups with different preoperative disability were also estimated. Results: When defining success after surgery for lumbar disc herniation, the accuracy (sensitivity, specificity, area under the curve, 95% CI) for the ODI raw score (0.83, 0.87, 0.930, 0.924-0.937) was comparable to the ODI percentage change score (0.85, 0.85, 0.925, 0.918-0.931), and higher than the ODI change score (0.79, 0.73, 0.838, 0.830-0.852). The cutoff for success was highly dependent on the amount of baseline disability (low-high), with cutoffs ranging from 13 to 28 for the ODI raw score and 39% to 66% for ODI percentage change. The ODI change score (points) was not as accurate. Conclusion: The 12-month ODI raw score, like the ODI percentage change score, can define a successful outcome with excellent accuracy. Adjustment for the baseline ODI score should be performed when comparing outcomes across groups, and one should consider using cutoffs according to preoperative disability (low, medium, high ODI scores).

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Randell, R., E. M. Borycki und C. E. Kuziemsky. „Understanding Unintended Consequences and Health Information Technology“. Yearbook of Medical Informatics 25, Nr. 01 (August 2016): 53–60. http://dx.doi.org/10.15265/iy-2016-027.

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SummaryObjective: No framework exists to identify and study unintended consequences (UICs) with a focus on organizational and social issues (OSIs). To address this shortcoming, we conducted a literature review to develop a framework for considering UICs and health information technology (HIT) from the perspective of OSIs.Methods: A literature review was conducted for the period 2000-2015 using the search terms “unintended consequences” and “health information technology”. 67 papers were screened, of which 18 met inclusion criteria. Data extraction was focused on the types of technologies studied, types of UICs identified, and methods of data collection and analysis used. A thematic analysis was used to identify themes related to UICs.Results: We identified two overarching themes. One was the definition and terminology of how people classify and discuss UICs. Second was OSIs and UICs. For the OSI theme, we also identified four sub-themes: process change and evolution, individual-collaborative interchange, context of use, and approaches to model, study, and understand UICs.Conclusions: While there is a wide body of research on UICs, there is a lack of overall consensus on how they should be classified and reported, limiting our ability to understand the implications of UICs and how to manage them. More mixed-methods research and better proactive identification of UICs remain priorities. Our findings and framework of OSI considerations for studying UICs and HIT extend existing work on HIT and UICs by focusing on organizational and social issues.

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Okazaki, Taichiro, Dimitrios G. Lignos, Mitsumasa Midorikawa, James M. Ricles und Jay Love. „Damage to Steel Buildings Observed after the 2011 Tohoku-Oki Earthquake“. Earthquake Spectra 29, Nr. 1_suppl (März 2013): 219–43. http://dx.doi.org/10.1193/1.4000124.

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A joint U.S.–Japan reconnaissance team examined the damage to steel building structures caused by the 2011 Tohoku-oki earthquake. In the city of Sendai, where the peak horizontal ground acceleration exceeded 1 g, the majority of steel buildings performed well. Buildings that used older cladding systems for external finish sustained damage to their claddings even if their structural performance was excellent. Damage to a few braced frames offer insight into the seismic design of bracing connections. In areas attacked by the violent tsunami, many steel buildings stood upright after the tsunami subsided, although these buildings lost much of their external and internal finishes along with their contents. These steel buildings did not provide safe shelter for tsunami evacuation when the building submerged under the tsunami wave. A number of buildings suffered foundation failure, which was likely caused by scouring or liquefaction or a combination of multiple effects.

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Coudoux, François-Xavier. „Extending Coverage of High Definition TV Services over ADSL2 with Optimized Reception Quality using H.264/AVC Transrating“. Journal of Communications Software and Systems 8, Nr. 3 (21.09.2012): 68. http://dx.doi.org/10.24138/jcomss.v8i3.168.

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In this paper, we present a new Joint Source-Channel Coding (JSCC) architecture to extend the coverage of H.264/AVC High Definition (HD) video delivery over Digital Subscriber Line (DSL). The proposed solution combines low complexity H.264/AVC transrating as well as multi-carrier transmission and takes into account realistic ADSL2 specifications including all OSI layers. Both transrating and bit and power loading transmission parameters are automatically optimized in terms of end-user perceived quality, with respect to the characteristics of the given subscriber’s loop. Several originalities have been included: a new optimization algorithm has been developed, as well as a full rate-distortion modelling of the H.264/AVC transrater’s performances. Simulation results show that the proposed solution can extend the coverage area of HD video delivery up to more than one kilometre. It should allow the widespread distribution of HD video contents and increase the number of eligible subscribers.

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Valls Carbó, Adrián, María Gutiérrez Sánchez de la Fuente, Carlos Pérez García und Maria Natividad Gómez Ruiz. „Orbital infarction syndrome after mechanical thrombectomy in acute ischaemic stroke“. BMJ Case Reports 13, Nr. 5 (Mai 2020): e234158. http://dx.doi.org/10.1136/bcr-2019-234158.

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Orbital infarction syndrome (OIS) encompasses the ischaemic infarction of all intraorbital and intraocular structures (optic nerve, extraocular muscles and orbital fat) which leads to a painful loss of visual acuity, ophthalmoparesis, chemosis, proptosis and ptosis. The rich anastomotic orbital vascularisation from internal carotid artery (ICA) and external carotid artery makes this disorder a rare cause of visual loss in stroke patients. We describe a case of a woman who suffered an acute occlusion of her right ICA and developed an OIS after mechanical thrombectomy.

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Fu, Dejian, Susan S. Kulawik, Kazuyuki Miyazaki, Kevin W. Bowman, John R. Worden, Annmarie Eldering, Nathaniel J. Livesey et al. „Retrievals of tropospheric ozone profiles from the synergism of AIRS and OMI: methodology and validation“. Atmospheric Measurement Techniques 11, Nr. 10 (12.10.2018): 5587–605. http://dx.doi.org/10.5194/amt-11-5587-2018.

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Abstract. The Tropospheric Emission Spectrometer (TES) on the A-Train Aura satellite was designed to profile tropospheric ozone and its precursors, taking measurements from 2004 to 2018. Starting in 2008, TES global sampling of tropospheric ozone was gradually reduced in latitude, with global coverage stopping in 2011. To extend the record of TES, this work presents a multispectral approach that will provide O3 data products with vertical resolution and measurement error similar to TES by combining the single-footprint thermal infrared (TIR) hyperspectral radiances from the Aqua Atmospheric Infrared Sounder (AIRS) instrument and the ultraviolet (UV) channels from the Aura Ozone Monitoring Instrument (OMI). The joint AIRS+OMI O3 retrievals are processed through the MUlti-SpEctra, MUlti-SpEcies, MUlti-SEnsors (MUSES) retrieval algorithm. Comparisons of collocated joint AIRS+OMI and TES to ozonesonde measurements show that both systems have similar errors, with mean and standard deviation of the differences well within the estimated measurement error. AIRS+OMI and TES have slightly different biases (within 5 parts per billion) vs. the sondes. Both AIRS and OMI have wide swath widths (∼1650 km for AIRS; ∼2600 km for OMI) across satellite ground tracks. Consequently, the joint AIRS+OMI measurements have the potential to maintain TES vertical sensitivity while increasing coverage by 2 orders of magnitude, thus providing an unprecedented new data set with which to quantify the evolution of tropospheric ozone.

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Hirashiki, Akihiro, Shiro Adachi, Yoshihisa Nakano, Yoshihiro Kamimura, Takeshi Ogo, Norifumi Nakanishi, Takayuki Morisaki et al. „Left main coronary artery compression by a dilated main pulmonary artery and left coronary sinus of Valsalva aneurysm in a patient with heritable pulmonary arterial hypertension and FLNA mutation“. Pulmonary Circulation 7, Nr. 3 (29.06.2017): 734–40. http://dx.doi.org/10.1177/2045893217716107.

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Left main coronary artery (LMCA) disease due to external compression by a dilated main pulmonary artery (MPA) is an uncommon clinical entity. Here, we describe a 52-year-old woman with pulmonary arterial hypertension (PAH) and anteroseptal old myocardial infarction (OMI). The cause of the OMI was external compression of the LMCA by the dilated MPA and aneurysm of the left coronary sinus of Valsalva. The patient’s sister (aged 56 years) had also been diagnosed with PAH and both women had a novel heterozygous splicing mutation, IVS2-2A > G (c.374-2A > G in NM_001456), in the filamin A ( FLNA) gene. To our knowledge, this is the first report of HPAH which is likely to be due to FLNA mutation and compression of the LMCA between a dilated MPA and aneurysm of the left coronary sinus of Valsalva.

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Cuinas, Inigo. „An Introduction to Cybersecurity at Physical Layer: Obstacles at Radio Channel to Mitigate Hackers’ Chance“. Elektronika ir Elektrotechnika 26, Nr. 6 (18.12.2020): 58–65. http://dx.doi.org/10.5755/j01.eie.26.6.28006.

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Cybersecurity commonly focuses on higher layers of Open Systems Interconnection (OSI) model, as it is a discipline associated to Computer Science. However, physical layer is the front line of the defence of a system against external attacks, and Electrical Engineering, concretely Radiofrequency Engineering, can provide tools to reinforce radio networks also in terms of information security. This paper analyses different techniques related to site shielding. From hard traditional shielding, similar to Faraday cages, to different soft shielding solutions as vegetation fences and frequency selective surfaces (FSS), the variety of solutions is broad and would be useful in actual deployments. Finally, Building Information Modelling (BIM) appears as an interesting tool that could be incorporated along the design and construction of an office building to improve the electromagnetic behaviour, and subsequently the cybersecurity issues of the communication networks hosted by the building itself.

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Nam, Seong-Won. „OS8-2-4 A Study on the Characteristics of Internal and External Pressure Variation for KTX“. Abstracts of ATEM : International Conference on Advanced Technology in Experimental Mechanics : Asian Conference on Experimental Mechanics 2007.6 (2007): _OS8–2–4–1—_OS8–2–4–5. http://dx.doi.org/10.1299/jsmeatem.2007.6._os8-2-4-1.

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Pereira, S., L. Nogueira, F. Canova, M. Lopez und HC Silva. „IRAK1variant is protective for orthodontic-induced external apical root resorption“. Oral Diseases 22, Nr. 7 (26.07.2016): 658–64. http://dx.doi.org/10.1111/odi.12514.

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Stephany, Fabian, Otto Kässi, Uma Rani und Vili Lehdonvirta. „Online Labour Index 2020: New ways to measure the world’s remote freelancing market“. Big Data & Society 8, Nr. 2 (Juli 2021): 205395172110432. http://dx.doi.org/10.1177/20539517211043240.

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The Online Labour Index (OLI) was launched in 2016 to measure the global utilisation of online freelance work at scale. Five years after its creation, the OLI has become a point of reference for scholars and policy experts investigating the online gig economy. As the market for online freelancing work matures, a high volume of data and new analytical tools allow us to revisit half a decade of online freelance monitoring and extend the index's scope to more dimensions of the global online freelancing market. While (still) measuring the utilisation of online labour across countries and occupations by tracking the number of projects and tasks posted on major English-language platforms, the new Online Labour Index 2020 (OLI 2020) also tracks Spanish- and Russian-language platforms, reveals changes over time in the geography of labour supply and estimates female participation in the online gig economy. The rising popularity of software and tech work and the concentration of freelancers on the Indian subcontinent are examples of the insights that the OLI 2020 provides. The OLI 2020 delivers a more detailed picture of the world of online freelancing via an interactive online visualisation updated daily. It provides easy access to downloadable open data for policymakers, labour market researchers, and the general public ( www.onlinelabourobservatory.org ).

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Borilova Linhartova, P., P. Cernochova, J. Kastovsky, Z. Vrankova, M. Sirotkova und L. Izakovicova Holla. „Genetic determinants and postorthodontic external apical root resorption in Czech children“. Oral Diseases 23, Nr. 1 (29.08.2016): 29–35. http://dx.doi.org/10.1111/odi.12564.

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Jansen, H., K. Fehske, M. Jordan und R. Meffert. „OS7-50 Minimal-invasive treatment of adolescent proximal fractures of the tibia by external fixation“. Injury 47 (Oktober 2016): S19. http://dx.doi.org/10.1016/s0020-1383(16)30536-8.

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Pawlowski, Jason Mark, Tammy Wotring und Andrew S. Kennedy. „The radiation oncology EMR as a quality and outcomes-based informatics platform: A multicenter pilot study.“ Journal of Clinical Oncology 34, Nr. 7_suppl (01.03.2016): 168. http://dx.doi.org/10.1200/jco.2016.34.7_suppl.168.

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168 Background: Radiation oncology specific oncology information systems (OIS) are highly specialized and capture large amounts of rich data related to patient care. There is great potential to expand the utility of these systems from data collection and point-of-care documentation to platforms for radiation oncology informatics. To this end, we have begun an effort to consolidate and standardize the OIS within a large network of radiation oncology clinics. We report initial findings from a multi-center OIS standardization pilot involving five clinics. Methods: Five radiation oncology clinics were converted from a paper-based medical record to an electronic medical record (EMR) on a single instance of the OIS. Clinician-led workgroups developed best-practice EMR workflows to ensure high-quality data were input into the OIS. Database configuration, clinical workflows, and documentation were standardized to enable consortium-wide reporting and dashboarding. Results: Standardization for the five radiation oncology centers was completed in September 2014. Clinical and operational dashboards were generated including dashboards to study radiation toxicity, treatment modality utilization, time studies for each task from referral to treatment, SRS/SBRT utilization, follow-up rates, and referral patterns. Consortium-wide analysis revealed substantive differences in operational and clinical practices. For example: IMRT utilization for prostate cancer patients treated with external beam radiotherapy ranged from 83% to 100% amongst facilities; the time required to contour target volumes on 80% of patients ranged from 2 to 10 days amongst physicians; and follow-up rates ranged from 50% to 83% amongst physicians. Conclusions: Standardization and consolidation of the radiation oncology OIS significantly increased reporting capabilities to include measures based on quality, safety, and patient outcomes. Disparate practices amongst radiation oncology clinics were observed and best practices discovered. OIS consolidation and standardization was essential to develop a consortium-wide understanding of clinical and operational quality.

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Cammaroto, Giovanni, Claudio Vicini, Filippo Montevecchi, Anna Bonsembiante, Giuseppe Meccariello, Lorenzo Bresciani, Stefano Pelucchi und Pasquale Capaccio. „Submandibular gland excision: From external surgery to robotic intraoral and extraoral approaches“. Oral Diseases 26, Nr. 5 (20.04.2020): 853–57. http://dx.doi.org/10.1111/odi.13340.

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Pope, A., T. A. Scambos, M. Moussavi, M. Tedesco, M. Willis, D. Shean und S. Grigsby. „Estimating supraglacial lake depth in western Greenland using Landsat 8 and comparison with other multispectral methods“. Cryosphere Discussions 9, Nr. 3 (22.06.2015): 3257–92. http://dx.doi.org/10.5194/tcd-9-3257-2015.

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Abstract. Liquid water stored on the surface of ice sheets and glaciers impacts surface mass balance, ice dynamics, and heat transport. Supraglacial lakes, therefore, play a significant role in ice sheet behavior as a surface expression of the glacial hydrological system. Multispectral remote sensing can be used to detect supraglacial lakes and estimate their depth and area. In this study, we use in situ spectral and bathymetric data to assess lake depth retrieval using the recently launched Landsat 8 Operational Land Imager (OLI). We also extend our analysis to other multispectral sensors to evaluate their performance with similar methods. Digital elevation models derived from WorldView stereo imagery (pre-lake filling and post-drainage) are used to validate spectrally derived depths, combined with a lake edge determination from imagery. The optimal supraglacial lake depth retrieval is a physically based single-band model applied to two OLI bands independently (red and panchromatic) that are then averaged together. When OLI- and WorldView-derived depths are differenced, they yield a mean and standard deviation of 0.0 ± 1.6 m. This method is then applied to OLI data for the Sermeq Kujalleq (Jakobshavn Isbrae) region of Greenland to study the spatial and intra-seasonal variability of supraglacial lakes during summer 2014. We also give coefficients for estimating supraglacial lake depth using a similar method as OLI with other multispectral sensors.

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Zhong, Yangfan. „LIBOR market model with multiplicative basis“. International Journal of Financial Engineering 05, Nr. 02 (Juni 2018): 1850014. http://dx.doi.org/10.1142/s2424786318500147.

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The study on the multiple-curve interest rate models becomes increasingly active since the 2007 credit crunch, for which one curve, typically the OIS curve, is used for discounting purpose, while the LIBOR curves (associated with various market tenors) are used for projecting the future cash flows. In this work, we extend the standard LIBOR market model to accommodate such multiple-curve setting by means of a multiplicative basis. The multiplicative basis is modeled as an exponential function of multi-factor square-root processes. Under the multiplicative basis setup, the OIS forward rates are correlated with the implied (additive) LIBOR-OIS spreads. We then derive closed-form pricing formulas for caplet, swaption, and interest rate futures in the multiplicative basis framework. In particular, we show that the valuation of caplet and swaption can be easily computed by a proper integral of real-valued functions, which facilitates the calibration of our model. Finally, we discuss a slight modification of our model to allow for negative interest rates.

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PESTANA DELGADO, Roberto, Luis Fernando LLANOS ZAVALAGA, Emilio Andrés CABELLO MORALES und Leonid LECCA GARCIA. „Concordancia entre el diagnóstico médico y la codificación de informática, considerando el CIE-10, en la consulta externa de pediatria en el Hospital Nacional Cayetano Heredia, Lima-Perú.“ Revista Medica Herediana 16, Nr. 4 (03.01.2013): 239. http://dx.doi.org/10.20453/rmh.v16i4.802.

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Objetivo: Determinar la concordancia de los diagnósticos registrados por los médicos con la nomenclatura de la CIE-10 y verificar su conformidad con la descripción de los códigos asignados por los digitadores de la Oficina de Estadística e Informática (OEI). Materiales y métodos: Estudio transversal descriptivo de corte retrospectivo. Se tomó una muestra aleatoria de 384 atenciones realizadas en Consultorio Externo de Pediatría General y Especialidades Pediátricas del Hospital Nacional Cayetano Heredia (HNCH) en el mes de enero del 2004. Anotándose los diagnósticos registrados por los médicos se procedió a describir las características de los diagnósticos en un proceso de codificación teniendo como base la CIE-10. Resultados: De los diagnósticos registrados por los médicos (533), 79,7% (425) fueron compatibles con la CIE-10 y 91,4% (487) fueron codificados por el personal de estadística del HNCH. La concordancia entre el diagnóstico médico y la codificación de informática total fue de 49,2%, subiendo a 53,8% cuando sólo se consideran los términos diagnósticos codificados. Conclusiones: Al final de un proceso de codificación en el Servicio de Consulta Externa de Pediatría General y Especialidades Pediátricas del HNCH se pierde la calidad (validez) del 50,8% de la información generada por los médicos. Se recomienda implementar mecanismos que permitan mejorar la calidad de la información registrada mediante capacitación del personal involucrado y comprometer a los profesionales médicos a la codificación correspondiente.

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Senn, Joseph, Vilmos Csizmadia, Paul Hales, Larry Dick und Vivek J. Kadambi. „Proteasome Inhibitors Do Not Inhibit the Serine Protease HtrA2/Omi“. Blood 120, Nr. 21 (16.11.2012): 5023. http://dx.doi.org/10.1182/blood.v120.21.5023.5023.

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Abstract Abstract 5023 Based on unprecedented efficacy, the proteasome inhibitor (PI) bortezomib has become the cornerstone of multiple myeloma treatment. Nevertheless, in a subset of patients bortezomib causes painful peripheral neuropathy and this side effect can limit its potential benefit for those patients. Although the mechanism of bortezomib associated neuropathy is unknown, we have previously suggested that it is related to the mechanism of action (Csizmadia at. al. Vet Pathol 2010; 47:358–367.). Recently Arastu-Kapur et al. (Clin Cancer Res 2011;17:2734–2743.) have reported that the serine protease HtrA2/Omi was inhibited by bortezomib (a peptide boronate proteasome inhibitor) and not by carfilzomib (an epoxyketone proteasome inhibitor). Further, since HtrA2/Omi is involved in neuronal survival (Martins et al. Mol Cell Biol 2004; 24: 9848–9862.) they suggested that this off target inhibition by bortezomib could be the mechanism underlying bortezomib associated peripheral neuropathy. To confirm and extend these published results, we investigated the effects of these two PIs on HtrA2/Omi activity in recombinant enzyme assays, in SH-SY5Y neuroblastoma-, and wild type and HtrA2/Omi double negative mouse embryonic fibroblast cells (MEF). In contrast to the results of Arastu-Kapur et al., our results clearly demonstrated that neither bortezomib nor carfilzomib inhibits HtrA2/Omi in recombinant enzyme assays at concentrations up to 100μM. As a positive control we used Ucf-101 an HtrA2/Omi specific inhibitor (Cilenti et al. J Biol Chem 2003; 278:11489–11494.) which in our assay behaved in a manner consistent with the published literature. Similarly, in MEF cells, only Ucf-101 prevented the degradation of validated HtrA2/Omi substrates eIF4G1 and UCH-L1, while neither bortezomib nor carfilzomib prevented the degradation of these two substrates. In conclusion, we have assessed the protease activity of HtrA2/Omi both in vitro with purified enzyme and in cultured cells and we find that neither PI inhibits this protease. Therefore we think it is unlikely that PI associated peripheral neuropathy is caused by off target inhibition of HtrA2/Omi. Further research is needed to understand the side effects of PIs. Disclosures: Senn: Millennium Pharmaceuticals, Inc.: Employment. Csizmadia:Millennium Pharmaceuticals, Inc.: Employment. Hales:Millennium Pharmaceuticals, Inc.: Employment. Dick:Millennium Pharmaceuticals, Inc.: Employment. Kadambi:Millennium Pharmaceuticals, Inc.: Employment.

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Frendy und HU Dan Semba. „Does recycling improve information usefulness of income? The case of Japan“. Asian Review of Accounting 25, Nr. 3 (11.09.2017): 376–403. http://dx.doi.org/10.1108/ara-11-2015-0111.

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Purpose The Accounting Standards Board of Japan (ASBJ) proposed a new set of endorsed International Financial Reporting Standards in June 2015. ASBJ claims that non-recycling of other comprehensive income (OCI) items decreases the information usefulness of earnings in a proposed comprehensive income standard. There has been no existing empirical evidence which supports the ASBJ’s statement and the purpose of the study is to test whether OCI recycling improves information usefulness of net income from six perspectives: relative and incremental value relevance, persistence, variability, operating cash flow and net income predictive power. Design/methodology/approach This paper is an empirical work using a listed Japanese firms sample of 5,385 firm-years from fiscal year 2012-2014. Findings The results challenge the ASBJ’s claim that recycling improves the general information usefulness characteristics of net income. The empirical results show that OCI recycling improves net income’s relative value relevance characteristic of financial firms. However, recycling information by itself does not improve the incremental value relevance, and the predictive power of operating cash flow and net income. The authors also find that the inclusion of recycling decreases the persistence and increases the variability of net income. Research limitations/implications This paper has two research limitations. First, this study is constrained to analyze a limited OCI recycling data that is recently disclosed by listed Japanese firms. Second, the results of this study have limited external validity to capital markets with OCI reclassification standards that deviate from Japanese GAAP. Originality/value This study provides initial empirical evidence that examines information usefulness of OCI recycling in Japan. The findings of this study are relevant for accounting standards setters aiming to increase the information usefulness of earnings for capital market investors.

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Pope, A., T. A. Scambos, M. Moussavi, M. Tedesco, M. Willis, D. Shean und S. Grigsby. „Estimating supraglacial lake depth in West Greenland using Landsat 8 and comparison with other multispectral methods“. Cryosphere 10, Nr. 1 (15.01.2016): 15–27. http://dx.doi.org/10.5194/tc-10-15-2016.

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Abstract. Liquid water stored on the surface of ice sheets and glaciers impacts surface mass balance, ice dynamics, and heat transport. Multispectral remote sensing can be used to detect supraglacial lakes and estimate their depth and area. In this study, we use in situ spectral and bathymetric data to assess lake depth retrieval using the recently launched Landsat 8 Operational Land Imager (OLI). We also extend our analysis to other multispectral sensors to evaluate their performance with similar methods. Digital elevation models derived from WorldView stereo imagery (pre-lake filling and post-drainage) are used to validate spectrally derived depths, combined with a lake edge determination from imagery. The optimal supraglacial lake depth retrieval is a physically based single-band model applied to two OLI bands independently (red and panchromatic) that are then averaged together. When OLI- and WorldView-derived depths are differenced, they yield a mean and standard deviation of 0.0 ± 1.6 m. This method is then applied to OLI data for the Sermeq Kujalleq (Jakobshavn Isbræ) region of Greenland to study the spatial and intra-seasonal variability of supraglacial lakes during summer 2014. We also give coefficients for estimating supraglacial lake depth using a similar method with other multispectral sensors.

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Nagy, Endre, Imre Hegedüs, Danyal Rehman, Quantum J. Wei, Yvana D. Ahdab und John H. Lienhard. „The Need for Accurate Osmotic Pressure and Mass Transfer Resistances in Modeling Osmotically Driven Membrane Processes“. Membranes 11, Nr. 2 (14.02.2021): 128. http://dx.doi.org/10.3390/membranes11020128.

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The widely used van ’t Hoff linear relation for predicting the osmotic pressure of NaCl solutions may result in errors in the evaluation of key system parameters, which depend on osmotic pressure, in pressure-retarded osmosis and forward osmosis. In this paper, the linear van ’t Hoff approach is compared to the solutions using OLI Stream Analyzer, which gives the real osmotic pressure values. Various dilutions of NaCl solutions, including the lower solute concentrations typical of river water, are considered. Our results indicate that the disparity in the predicted osmotic pressure of the two considered methods can reach 30%, depending on the solute concentration, while that in the predicted power density can exceed over 50%. New experimental results are obtained for NanoH2O and Porifera membranes, and theoretical equations are also developed. Results show that discrepancies arise when using the van ’t Hoff equation, compared to the OLI method. At higher NaCl concentrations (C > 1.5 M), the deviation between the linear approach and the real values increases gradually, likely indicative of a larger error in van ’t Hoff predictions. The difference in structural parameter values predicted by the two evaluation methods is also significant; it can exceed the typical 50–70% range, depending on the operating conditions. We find that the external mass transfer coefficients should be considered in the evaluation of the structural parameter in order to avoid overestimating its value. Consequently, measured water flux and predicted structural parameter values from our own and literature measurements are recalculated with the OLI software to account for external mass transfer coefficients.

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Y.-X., MICHAEL, BIJI JACOB-SAMUEL, JEANNE C. DIGNAM, UMBERTO PACE, ALLAN R. GOLDBERG und SHAJI T. GEORGE. „Nuclease-Resistant External Guide Sequence-Induced Cleavage of Target RNA by Human Ribonuclease P“. Antisense and Nucleic Acid Drug Development 8, Nr. 5 (Oktober 1998): 415–26. http://dx.doi.org/10.1089/oli.1.1998.8.415.

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WERNER, MARTINA, EDDIE ROSA, OBAIDULLAH AL EMRAN, ALLAN R. GOLDBERG und SHAJI T. GEORGE. „Targeted Cleavage of RNA Molecules by Human RNase P Using Minimized External Guide Sequences“. Antisense and Nucleic Acid Drug Development 9, Nr. 1 (Februar 1999): 81–88. http://dx.doi.org/10.1089/oli.1.1999.9.81.

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Iglesias-Linares, A., RM Yañez-Vico, AM Moreno-Fernández, A. Mendoza-Mendoza, A. Orce-Romero und E. Solano-Reina. „Osteopontin gene SNPs (rs9138, rs11730582) mediate susceptibility to external root resorption in orthodontic patients“. Oral Diseases 20, Nr. 3 (25.04.2013): 307–12. http://dx.doi.org/10.1111/odi.12114.

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Pass, Jonathan. „China’s Institutional Statecraft Within the Liberal International Order: The Asian Infrastructure Investment Bank“. Spanish Yearbook of International Lawi 2, Nr. 72 (03.09.2020): 89–115. http://dx.doi.org/10.17103/redi.72.2.2020.1a.03.

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Un debate clave entre los teóricos de Relaciones Internacionales es cómo el auge de China afectará al orden liberal internacional (OLI). No es extraño, por tanto, que la creación del Banco Asiático de Inversión en Infraestructura (BAII) por parte de Beijing, haya despertado mucho interés. El objetivo de este artículo se centra en examinar la afirmación de que el BAII constituye una iniciativa «contrahegemónica» (o una «innovación externa» en terminología liberal). Una vez demostrada la complejidad del statecraft institucional chino, el estudio analiza las perspectivas de las teorías convencionales sobre el BAII. Sostenemos que tanto el neorrealismo como el neoliberalismo han contribuido a una mejor comprensión de la institución, pero sus deficiencias ontológicas y epistemológicas constituyen un obstáculo para explicar de forma convincente los complicados procesos sociales en marcha. De ahí que expongamos aquí una perspectiva Neo neogramsciana que comprende el BAII como una manifestación institucional de la interacción en curso entre las fuerzas sociales emergentes del complejo Estado-sociedad chino, por un lado, y sus homologas globales, por el otro. Concluimos que es probable que el BAII refuerce el OLI a corto plazo. A medio y largo plazo, sin embargo, este proceso de internacionalización del Estado, entendido en conexión con la Iniciativa de la Franja y la Ruta, puede suponer un desafío grave para el OLI y, por ende, para la hegemonía americana en sí misma.

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Takenaka, Kazuhito, Yasuo Nagasaka, Sayaka Hihara, Hiroyuki Nakahara, Atsushi Iriki, Yasuo Kuniyoshi und Naotaka Fujii. „Linear Discrimination Analysis of Monkey Behavior in an Alternative Free Choice Task“. Journal of Robotics and Mechatronics 19, Nr. 4 (20.08.2007): 416–22. http://dx.doi.org/10.20965/jrm.2007.p0416.

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When we observe people, we can often comprehend their intention from their behaviors. The intentions expressed by individuals can be considered as existing in interpersonal space and from a current social context. In our daily activity, choosing socially correct behavior through the observation of such social context is essential. However, it is not known how we can decode intention from another’s behavior. Here, we show how we can retrieve the intention of monkeys through external observation of their behavior patterns while performing alternative free choice tasks. We found that linear discriminant analysis on a monkey’s motion parameters could provide a discriminant score that appears to reflect the internal decision making process. The score showed a clear flexion point that we defined as a moment of outward expression of intention (OEI). This suggests that an alternative decision is made just before an OEI and that intention is expressed in the environment after this OEI in behavior, which in turn suggests that discriminant analysis may be useful in indicating how the brain implements nonverbal social communication. If we could embed the function in a human-machine interfaces, it could enable intuitive, smooth communication between machines and humans.

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Chochi, Michiyo, Yasuaki Niizuma und Masaoki Takagi. „Sexual differences in the external measurements of Black-tailed Gulls breeding on Rishiri Island, Japan“. ORNITHOLOGICAL SCIENCE 1, Nr. 2 (2002): 163–66. http://dx.doi.org/10.2326/osj.1.163.

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Moses, K., und C. Prives. „A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication.“ Molecular and Cellular Biology 14, Nr. 4 (April 1994): 2767–76. http://dx.doi.org/10.1128/mcb.14.4.2767.

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Murine cells or cell extracts support the replication of plasmids containing the replication origin (ori-DNA) of polyomavirus (Py) but not that of simian virus 40 (SV40), whereas human cells or cell extracts support the replication of SV40 ori-DNA but not that of Py ori-DNA. It was shown previously that fractions containing DNA polymerase alpha/primase from permissive cells allow viral ori-DNA replication to proceed in extracts of nonpermissive cells. To extend these observations, the binding of Py T antigen to both the permissive and nonpermissive DNA polymerase alpha/primase was examined. Py T antigen was retained by a murine DNA polymerase alpha/primase but not by a human DNA polymerase alpha/primase affinity column. Likewise, a Py T antigen affinity column retained DNA polymerase alpha/primase activity from murine cells but not from human cells. The murine fraction which bound to the Py T antigen column was able to stimulate Py ori-DNA replication in the nonpermissive extract. However, the DNA polymerase alpha/primase activity in this murine fraction constituted only a relatively small proportion (approximately 20 to 40%) of the total murine DNA polymerase alpha/primase that had been applied to the column. The DNA polymerase alpha/primase purified from the nonbound murine fraction, although far more replete in this activity, was incapable of supporting Py DNA replication. The two forms of murine DNA polymerase alpha/primase also differed in their interactions with Py T antigen. Our data thus demonstrate that there are two distinct populations of DNA polymerase alpha/primase in murine cells and that species-specific interactions between T antigen and DNA polymerases can be identified. They may also provide the basis for initiating a novel means of characterizing unique subpopulations of DNA polymerase alpha/primase.

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Moses, K., und C. Prives. „A unique subpopulation of murine DNA polymerase alpha/primase specifically interacts with polyomavirus T antigen and stimulates DNA replication“. Molecular and Cellular Biology 14, Nr. 4 (April 1994): 2767–76. http://dx.doi.org/10.1128/mcb.14.4.2767-2776.1994.

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Murine cells or cell extracts support the replication of plasmids containing the replication origin (ori-DNA) of polyomavirus (Py) but not that of simian virus 40 (SV40), whereas human cells or cell extracts support the replication of SV40 ori-DNA but not that of Py ori-DNA. It was shown previously that fractions containing DNA polymerase alpha/primase from permissive cells allow viral ori-DNA replication to proceed in extracts of nonpermissive cells. To extend these observations, the binding of Py T antigen to both the permissive and nonpermissive DNA polymerase alpha/primase was examined. Py T antigen was retained by a murine DNA polymerase alpha/primase but not by a human DNA polymerase alpha/primase affinity column. Likewise, a Py T antigen affinity column retained DNA polymerase alpha/primase activity from murine cells but not from human cells. The murine fraction which bound to the Py T antigen column was able to stimulate Py ori-DNA replication in the nonpermissive extract. However, the DNA polymerase alpha/primase activity in this murine fraction constituted only a relatively small proportion (approximately 20 to 40%) of the total murine DNA polymerase alpha/primase that had been applied to the column. The DNA polymerase alpha/primase purified from the nonbound murine fraction, although far more replete in this activity, was incapable of supporting Py DNA replication. The two forms of murine DNA polymerase alpha/primase also differed in their interactions with Py T antigen. Our data thus demonstrate that there are two distinct populations of DNA polymerase alpha/primase in murine cells and that species-specific interactions between T antigen and DNA polymerases can be identified. They may also provide the basis for initiating a novel means of characterizing unique subpopulations of DNA polymerase alpha/primase.

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SHIMADA, Takahiro, Hiroshi SAKAMOTO und Takayuki KITAMURA. „814 Instability Criterion for Ferroelectrics under External Electric Fields“. Proceedings of The Computational Mechanics Conference 2011.24 (2011): 254–56. http://dx.doi.org/10.1299/jsmecmd.2011.24.254.

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Bingham, Jonathan L., Patricia E. Carrigan, Laurence J. Miller und Subha Srinivasan. „Extent and Diversity of Human Alternative Splicing Established by Complementary Database Annotation and Microarray Analysis“. OMICS: A Journal of Integrative Biology 12, Nr. 1 (März 2008): 83–92. http://dx.doi.org/10.1089/omi.2007.0041.

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Loveless, John P., und Brendan J. Meade. „Spatial correlation of interseismic coupling and coseismic rupture extent of the 2011 MW= 9.0 Tohoku-oki earthquake“. Geophysical Research Letters 38, Nr. 17 (September 2011): n/a. http://dx.doi.org/10.1029/2011gl048561.

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Igbokwe, DI, und UE Udofia. „Approximation of common fixed points of a finite family of Ø - demicontractive mappings by an implicit iteration method.“ Global Journal of Mathematical Sciences 12, Nr. 1 (19.01.2015): 31–38. http://dx.doi.org/10.4314/gjmas.v12i1.15.

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We prove that the Implicit Iteration process of Xu and Ori (2001) converges strongly to the commonfixed pointsof a finite family of Ø - demicontractive mappings in real Hilbertand Banachspaces. Our results extend the results of Osilike (2004a) from strictl pseudocontractive maps to the much more general Ø - demicontractive maps;complement and generalize several others in the literature.KEY WORDS AND PHRASES: Ø - Demicontractive Maps, Implicit Iteration Process, Fixed Points,Strong Convergence.

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Yan, H., L. Chen, J. Tao, L. Su, J. Huang, D. Han und C. Yu. „Corrections for OMI SO2 BRD retrievals influenced by row anomalies“. Atmospheric Measurement Techniques 5, Nr. 11 (06.11.2012): 2635–46. http://dx.doi.org/10.5194/amt-5-2635-2012.

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Abstract. Since June 2007, the Ozone Monitoring Instrument (OMI) Earth radiance data at specific viewing angles have been affected by the row anomaly, which causes large biases in sulfur dioxide (SO2) columns retrieved using the band residual difference (BRD) algorithm. To improve global measurements of atmospheric SO2 from OMI, we developed two correction approaches for the row anomaly effects in the northern latitudes and along the full orbit. Firstly the residual correction approach with median residual from a sliding 10° latitude range, and with that near the Equator was used to remove the anomalous high SO2 columns in the northern latitudes. Secondly, in the case of the row anomaly along the full orbit, the SO2 biases caused by the anomalous ozone (O3) column and underestimated Lambertian effective reflectivity (LER) were reduced, respectively, by using unaffected adjacent O3 column and residual correction with median residual from a sliding 10° latitude range. Comparisons with the OMI SO2 columns processed with median residual from a sliding 30° latitude range have illustrated the drastic improvements of our correction approaches under row anomaly conditions. The consistencies among the SO2 columns inside and outside the row anomaly areas have also demonstrated the effectiveness of our correction approaches under row anomaly conditions. The analyses of the underestimation and the errors caused by the O3 column and LER were conducted to understand the limitations of our correction approaches. The proposed approaches for the row anomaly effects can extend the valid range of OMI SO2 Planetary Boundary Layer (PBL) data produced using the BRD algorithm.

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Flores-Alsina, Xavier, Ignasi Rodriguez-Roda, Gürkan Sin und Krist V. Gernaey. „Uncertainty and sensitivity analysis of control strategies using the benchmark simulation model No1 (BSM1)“. Water Science and Technology 59, Nr. 3 (01.02.2009): 491–99. http://dx.doi.org/10.2166/wst.2009.871.

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The objective of this paper is to perform an uncertainty and sensitivity analysis of the predictions of the Benchmark Simulation Model (BSM) No. 1, when comparing four activated sludge control strategies. The Monte Carlo simulation technique is used to evaluate the uncertainty in the BSM1 predictions, considering the ASM1 bio-kinetic parameters and influent fractions as input uncertainties while the Effluent Quality Index (EQI) and the Operating Cost Index (OCI) are focused on as model outputs. The resulting Monte Carlo simulations are presented using descriptive statistics indicating the degree of uncertainty in the predicted EQI and OCI. Next, the Standard Regression Coefficients (SRC) method is used for sensitivity analysis to identify which input parameters influence the uncertainty in the EQI predictions the most. The results show that control strategies including an ammonium (SNH) controller reduce uncertainty in both overall pollution removal and effluent total Kjeldahl nitrogen. Also, control strategies with an external carbon source reduce the effluent nitrate (SNO) uncertainty increasing both their economical cost and variability as a trade-off. Finally, the maximum specific autotrophic growth rate (μA) causes most of the variance in the effluent for all the evaluated control strategies. The influence of denitrification related parameters, e.g. ηg (anoxic growth rate correction factor) and ηh (anoxic hydrolysis rate correction factor), becomes less important when a SNO controller manipulating an external carbon source addition is implemented.

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49

D’Angiulli, Amedeo, Darren Kenney, Dao Anh Thu Pham, Etienne Lefebvre, Justin Bellavance und Derrick Matthew Buchanan. „Neurofunctional Symmetries and Asymmetries during Voluntary out-of- and within-Body Vivid Imagery Concurrent with Orienting Attention and Visuospatial Detection“. Symmetry 13, Nr. 8 (23.08.2021): 1549. http://dx.doi.org/10.3390/sym13081549.

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We explored whether two visual mental imagery experiences may be differentiated by electroencephalographic (EEG) and performance interactions with concurrent orienting external attention (OEA) to stimulus location and subsequent visuospatial detection. We measured within-subject (N = 10) event-related potential (ERP) changes during out-of-body imagery (OBI)—vivid imagery of a vertical line outside of the head/body—and within-body imagery (WBI)—vivid imagery of the line within one’s own head. Furthermore, we measured ERP changes and line offset Vernier acuity (hyperacuity) performance concurrent with those imagery, compared to baseline detection without imagery. Relative to OEA baseline, OBI yielded larger N200 and P300, whereas WBI yielded larger P50, P100, N400, and P800. Additionally, hyperacuity dropped significantly when concurrent with both imagery types. Partial least squares analysis combined behavioural performance, ERPs, and/or event-related EEG band power (ERBP). For both imagery types, hyperacuity reduction correlated with opposite frontal and occipital ERP amplitude and polarity changes. Furthermore, ERP modulation and ERBP synchronizations for all EEG frequencies correlated inversely with hyperacuity. Dipole Source Localization Analysis revealed unique generators in the left middle temporal gyrus (WBI) and in the right frontal middle gyrus (OBI), whereas the common generators were in the left precuneus and middle occipital cortex (cuneus). Imagery experiences, we conclude, can be identified by symmetric and asymmetric combined neurophysiological-behavioural patterns in interactions with the width of attentional focus.

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Asyik, Nur Fadjrih. „DAMPAK STRUKTUR MODAL PADA SENSITIVITAS PENERAPAN KOMPENSASI OPSI SAHAM KARYAWAN TERHADAP KINERJA“. EKUITAS (Jurnal Ekonomi dan Keuangan) 14, Nr. 1 (02.02.2017): 1. http://dx.doi.org/10.24034/j25485024.y2010.v14.i1.2109.

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This study aims to test whether the management that receive compensation in the form of stock options having an positive impact on company performance. This study considers the external performance measurement by identifying Cumulative Abnormal Return (CAR). In addition, this study aims to test whether the company's capital structure affects the sensitivity level of employee stock option compensation and firm performance. Capital structure is measured with debt to equity ratio. The result indicates that the proportion of Employee Stock Option Plan (ESOP) influence company performance in accordance with the predictions. This shows that the more stock options offered to employees then came a sense of belonging which resulted in more motivated managers to improve company performance. Furthermore, the higher the market performance of companies that can be achieved, the higher the profit (gain) will be obtained by the recipient of stock options. In addition, this study also shows that the impact of stock option grants at the company's performance declined with the greater capital structure of liability. This shows that the capital structure of liabilities will lower the sensitivity level of employee stock option compensation and firm performance. The higher the company's liabilities would reduce the rights of the owner of the dividends each period in accordance with the ownership of shares held since the company must take into account the interest costs to be paid to the creditor.

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