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1

Han, Yihang, and Wensheng Wang. "Identification System for Electric Bicycle in Compartment Elevators." Electronics 14, no. 13 (2025): 2638. https://doi.org/10.3390/electronics14132638.

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Electric bicycles in elevators pose serious safety hazards. Fires in the confined space make escape difficult, and recent accidents involving e-bike fires have caused casualties and property damage. To prevent e-bikes from entering elevators and improve public safety, this design employs the Nezha development board as the upper computer for visual detection. It uses deep learning algorithms to recognize hazards like e-bikes. The lower computer orchestrates elevator controls, including voice alarms, door locking, and emergency halt. The system comprises two parts: the upper computer uses the YO
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Yu, Hengcheng, and Zhengyu Chen. "Research on contactless control of elevator based on machine vision." Highlights in Science, Engineering and Technology 7 (August 3, 2022): 89–94. http://dx.doi.org/10.54097/hset.v7i.1022.

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Aiming at the problem of cross-infection caused by elevator public buttons during the COVID-19 epidemic, a non-contact elevator button control gesture recognition system based on machine vision is designed. In order to improve the detection speed of gesture recognition, combined with the Spatial Pyramid Pooling (SPP) and replaced the Backbone in YOLOv5 with the lightweight model ShuffleNetV2, an improved YOLOv5_shff algorithm was proposed. After testing, in the task of recognizing gestures, the detection speed of the YOLOv5_shff algorithm is 14% higher than the original model, and the detectio
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Karanovic, Olivera, Michel Thabet, Hugh R. Wilson, and Frances Wilkinson. "Detection and discrimination of flicker contrast in migraine." Cephalalgia 31, no. 6 (2011): 723–36. http://dx.doi.org/10.1177/0333102411398401.

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Aims: Flickering light is strongly aversive to many individuals with migraine. This study was designed to evaluate other abnormalities in the processing of temporally modulating visual stimulation. Methods: We measured psychophysical thresholds for detection of a flickering target and for the discrimination of suprathreshold flicker contrasts (increment thresholds) in 14 migraineurs and 14 healthy controls with and without prior adaptation to high-contrast flicker. Visual discomfort (aversion) thresholds were also assessed. Results: In the baseline (no adaptation) conditions, detection and dis
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Suparmono, Trahman Sitepu, Aulia Salman, et al. "Control System Design for 3 Storey Elevator Using PLC OPTA FINDER." International Journal of Research in Vocational Studies (IJRVOCAS) 4, no. 4 (2025): 73–78. https://doi.org/10.53893/ijrvocas.v4i4.384.

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Elevators are a crucial vertical transportation system in multi-story buildings, and the use of an appropriate control system can enhance operational efficiency, comfort, and safety. This study aims to design a control system for a 3-floor elevator using a Programmable Logic Controller (PLC) OPTA FINDER, which offers advantages in flexibility and ease of programming. The design process involved creating a control system schematic, programming with ladder diagrams, and testing on a small-scale elevator model. The test results demonstrated that the system could operate the elevator with fast and
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Monimoy Chatterjee, Sanchayan Sinha, Mousumi Mukhopadhyay, Satwika Sinha, and Indranil Chakraborty. "Assessment of Cobalt Binding Activity of Albumin in COVID-19 Patients and its Correlation with CRP." Indian Journal of Public Health Research & Development 15, no. 2 (2024): 213–16. http://dx.doi.org/10.37506/775kfp65.

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Background: Covid 19 pandemic has thrown a big challenge in terms of available manpower, space and financial recourses at all levels of healthcare facilities. The disease manifestation ranges from asymptomatic to severe but a pro-inflammatory milieu is the underlying ongoing event. Detection of pro- inflammatory markers in early stages of the disease is instrumental to avert future complications.Method: For the present study 35 RT-PCR positive Covid patients were chosen from indoor admissions along with 35 age and sex matched controls. C Reactive Protein (CRP) and cobalt binding activity of al
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Martell, R. E., F. J. Xu, W. Z. Davis, et al. "OVX1 and CEA in Patients with Colon Carcinoma, Colon Polyps and Benign Colon Disorders." International Journal of Biological Markers 13, no. 3 (1998): 145–49. http://dx.doi.org/10.1177/172460089801300304.

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The OVX1 tumor marker promises to complement CA125 for detection of early stage ovarian carcinoma. OVX1 has also been shown to be elevated in colon cancer patients. This study is designed to assess serum OVX1 levels in patients with specific stages of colon cancer, colon polyps or other GI disorders. Serum OVX1 and CEA were measured by radioimmunoassay or enzyme immunoassay for 206 patients at the time of colonoscopy or staging for colon carcinoma. In patients with stage I, II, III, or IV colon carcinoma, serum OVX1 was positive in 37%, 48%, 74% and 63%, respectively. Fifty-three percent of pa
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Su, Jingfang, Minrui Yang, and Xinliang Tang. "Integration of ShuffleNet V2 and YOLOv5s Networks for a Lightweight Object Detection Model of Electric Bikes within Elevators." Electronics 13, no. 2 (2024): 394. http://dx.doi.org/10.3390/electronics13020394.

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The entry of electric bikes into elevators poses safety risks. This article proposes a lightweight object detection model for edge deployment in elevator environments specifically designed for electric bikes. Based on the YOLOv5s network, the backbone network replaces the original CSPDarknet53 with a lightweight multilayer ShuffleNet V2 convolutional neural network, achieving a lightweight backbone network. Swin Transformer modules are introduced between layers to enhance the feature expression capability of images, and a SimAM attention mechanism is applied at the end layer to further improve
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Yang, Bao Gui. "Fault Detection Expert System of Elevator Control Cabinet Based on LabView." Applied Mechanics and Materials 539 (July 2014): 596–600. http://dx.doi.org/10.4028/www.scientific.net/amm.539.596.

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An expert testing system of elevator control cabinet was developed based on LabView, for resolving the difficulties on elevator testing and elevator fault troubleshooting. With fault tree analysis algorithm, manual knowledge obtaining method was used, and forward reasoning strategy was employed for locating the possible reason of the system fault quickly and exactly. The system was modularized to reduce the complexity of the program. The graphical interface was programmed by LabView to improve human-computer interaction ability. The results indicated the expert system can be applied to system
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Selvarajah, Suganya, Sheila Keating, John Heitman, et al. "Detection of host immune responses in acute phase sera of spontaneous resolution versus persistent hepatitis C virus infection." Journal of General Virology 93, no. 8 (2012): 1673–79. http://dx.doi.org/10.1099/vir.0.041277-0.

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Prior to the identification of hepatitis C virus (HCV), transfusion-transmission was common. Viral transmission in subjects with a known date of infection allows the study of the immune responses to acute HCV infection. We analysed 39 soluble immune factors in serum samples from subjects with transfusion-transmitted HCV. Dynamic expression kinetics of interferon gamma-induced protein 10 (IP-10), tumour necrosis factor-alpha and interleukin (IL)-10 were observed during acute HCV infection. Serum IP-10 was the only analyte that was significantly elevated in HCV resolvers compared with uninfected
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Zheng, Yi Peng, Zu Tao Zhang, and Hong Xu. "A Novel Intelligent Elevator Group Control Algorithm Based on Corridor Passenger Detection and Tracking." Applied Mechanics and Materials 336-338 (July 2013): 815–19. http://dx.doi.org/10.4028/www.scientific.net/amm.336-338.815.

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The conventional elevator group control system is based on the button as a response and where to dispatch an elevator car. There is one big problem that when system dispatches the elevator to that button responding floor, but no passenger there and causing a waste of time and energy. In this paper, we present a novel intelligent elevator group control algorithm based on corridor passenger detection and tracking. In the above proposed system, after the corridor passengers are detected using binocular-cameras, Unscented Kalman Filter (UKF) is introduced to improve robustness and accuracy of corr
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Ai, Li, Sydney Flowers, Tanner Mesaric, Bryson Henderson, Sydney Houck, and Paul Ziehl. "Acoustic Emission-Based Detection of Impacts on Thermoplastic Aircraft Control Surfaces: A Preliminary Study." Applied Sciences 13, no. 11 (2023): 6573. http://dx.doi.org/10.3390/app13116573.

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The reliability of aircraft control surfaces, constructed from thermoplastic materials, can be affected by impacts from airborne particles. Recognizing the exact position of such impacts is essential for correctly estimating the resulting damage. This research intended to address the issue by introducing an innovative structural health monitoring solution capable of autonomously detecting and localizing impacts using acoustic emission monitoring. The objective of this research is to investigate the application of AE for the localization of impacts on aircraft elevators using machine learning t
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Wang, Pangwei, Yunfeng Wang, Xu Wang, Ying Liu, and Juan Zhang. "An Intelligent Actuator of an Indoor Logistics System Based on Multi-Sensor Fusion." Actuators 10, no. 6 (2021): 120. http://dx.doi.org/10.3390/act10060120.

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Integration technologies of artificial intelligence (AI) and autonomous vehicles play important roles in intelligent transportation systems (ITS). In order to achieve better logistics distribution efficiency, this paper proposes an intelligent actuator of an indoor logistics system by fusing multiple involved sensors. Firstly, an actuator based on a four-wheel differential chassis is equipped with sensors, including an RGB camera, a lidar and an indoor inertial navigation system, by which autonomous driving can be realized. Secondly, cross-floor positioning can be realized by multi-node simult
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Pepin, D., Michael Godeny, and Wen-Rong Lie. "A bead-based multiplex immunoassay for cancer autoantibody biomarker discovery." Journal of Immunology 200, no. 1_Supplement (2018): 120.43. http://dx.doi.org/10.4049/jimmunol.200.supp.120.43.

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Abstract Accurate, reliable and affordable blood tests are needed for early detection of cancer. Here we show data for the development and validation of a sensitive Luminex® bead-based multiplex immunoassay for detecting cancer autoantibodies in multiple cancer types. The cancer autoantibody biomarkers in this new multiplex panel include: CTAG1B/NY-ESO-1, Cyclin B/CCNB1, ENO1, Galectin-1, Galectin-3, Her2, HIF1α, HSP60, IMP2/IGF2BP2/p62, IMP3/IGF2BP3/KOC, MUC1, p16-INK4a, p53, SOX2, and Survivin/BIRC5. This multiplex immunoassay is sensitive and robust. In a 96-well plate, a mixture of recombi
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Rehman, Sadia, Santosh Kumar, Kashif Nisar, Zara Sami, Fatima Mehboob, and Suniya Rehman. "Association of Elevated Oxidized Low Density Lipoprotein to Low Density Lipoprotein Ratio (Ox LDL/LDL) with Sub Clinical Atherosclerosis in Patients Receiving Maintenance Haemodialysis." Annals of Jinnah Sindh Medical University 8, no. 1 (2022): 30–35. http://dx.doi.org/10.46663/ajsmu.v8i1.30-35.

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Objective: To assess the oxidized low density lipoprotein (ox-LDL) to low density lipoprotein (LDL) ratio as an indicator of subclinical atherosclerosis in haemodialysis patients Methodology: This case control study was carried out at Jinnah Post Graduate Medical Center Karachi, from January to December 2018. The haemodialysis patients were selected from the dialysis center (group B) whereas the controls were recruited from normal healthy population (group A). To access the status of atherosclerosis, doppler ultrasonography technique was employed to detect the intima media thickness (IMT) rati
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Harika, Vemugadda, Swathy Thilak, and Radhakrishan Narayanswamy. "The serum leptin can be a predictable marker for gestational diabetes mellitus." Indian Journal of Obstetrics and Gynecology Research 11, no. 2 (2024): 198–202. http://dx.doi.org/10.18231/j.ijogr.2024.040.

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This study assessed the serum leptin concentrations for development of gestational diabetes mellitusThis is a case-control study, included 120 participants (60: Gestational Diabetes Mellitus Cases and 60: Healthy Controls). We assed BMI, FBS, HbA1c, Lipid Profile and serum leptin. The serum leptin concentrations were significantly elevated in patients with gestational diabetes mellitus when compared to controls (P=0.001**). There was a significant positive correlation between the serum leptin and BMI, FBS, HbA1c, Total Cholesterol and LDL (P=0.001**). Based on study findings, significant eleva
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Baumann, Ralf, Susanne Kaempfer, Novel N. Chegou, et al. "A Subgroup of LatentlyMycobacterium tuberculosisInfected Individuals Is Characterized by Consistently Elevated IgA Responses to Several Mycobacterial Antigens." Mediators of Inflammation 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/364758.

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Elevated antibody responses toMycobacterium tuberculosisantigens in individuals with latent infection (LTBI) have previously been linked to an increased risk for progression to active disease. Studies in the field focussed mainly on IgG antibodies. In the present study, IgA and/or IgG responses to the mycobacterial protein antigens AlaDH, NarL, 19 kDa, PstS3, and MPT83 were determined in a blinded fashion in sera from 53 LTBI controls, 14 healthy controls, and 42 active TB subjects. Among controls, we found that elevated IgA levels against all investigated antigens were not randomly distribute
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K. V., Harish, Hareesh R., and Akshatha Savith. "Study of serum adiponectin levels for early detection of type 2 diabetes mellitus and its complications on kidney." International Journal of Advances in Medicine 8, no. 2 (2021): 171. http://dx.doi.org/10.18203/2349-3933.ijam20210102.

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Background: Type 2 diabetes mellitus is a chronic metabolic disorder due to insulin resistance caused by destruction of beta cells of pancreas. Insulin resistance in newly diagnosed type 2 diabetes mellitus patients leads to hyperglycemia. Serum adiponectin is a more sensitive and specific biomarker for early detection of diabetic nephropathy than urinary microalbuminuria.Methods: This is a case-control study conducted in Akash Institute of Medical Sciences, A total 180 subjects (120 cases and 60 controls). All the subjects included after informed consent, blood samples and urine samples are c
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Hoppensteadt, Debra, Sallu Jabati, Trung Phan, et al. "Increased Extracellular Nucleosome Levels and Microparticles in Atrial Fibrillation Patients Compared to the Age-Matched Normal Population." Blood 128, no. 22 (2016): 4912. http://dx.doi.org/10.1182/blood.v128.22.4912.4912.

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Abstract Introduction : Atrial fibrillation (AF) is currently the most common cardiac arrhythmia encountered in clinical practice and a major cause of morbidity and mortality among adults. It is estimated that atrial fibrillation affects approximately 2.7 million people in the United States. Extracellular plasma nucleosomes (PNs) are complexes of DNA and histones that are released during cell death. Histones have been shown to function as DAMPs when they are translocated from the nucleus to the extracellular space. It is hypothesized that these extracellular nucleosomes contribute to the obser
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Chen, Xu, Jiaxin Zhao, Katja C. Iselin, et al. "Keratoconus detection of changes using deep learning of colour-coded maps." BMJ Open Ophthalmology 6, no. 1 (2021): e000824. http://dx.doi.org/10.1136/bmjophth-2021-000824.

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ObjectiveTo evaluate the accuracy of convolutional neural networks technique (CNN) in detecting keratoconus using colour-coded corneal maps obtained by a Scheimpflug camera.DesignMulticentre retrospective study.Methods and analysisWe included the images of keratoconic and healthy volunteers’ eyes provided by three centres: Royal Liverpool University Hospital (Liverpool, UK), Sedaghat Eye Clinic (Mashhad, Iran) and The New Zealand National Eye Center (New Zealand). Corneal tomography scans were used to train and test CNN models, which included healthy controls. Keratoconic scans were classified
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Suchanda, Das, Yumnam Deepa, and Chandolia Umes. "Lipid profile and carotid intima–media thickness in xanthelasma palpebrarum: A case–control study in Northeast India." Our Dermatology Online 14, no. 3 (2023): 263–67. http://dx.doi.org/10.7241/ourd.20233.5.

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Background: Xanthelasma palpebrarum (XP) is a common cutaneous xanthoma often associated with dyslipidemia. Carotid intima–media thickness (CIMT) is a non-invasive method of monitoring subclinical atherosclerotic plaque formation and its progression. This study was conducted to assess the cardiovascular comorbidities in patients with XP by measuring the CIMT and serum lipid profile. Materials and Methods: A total of eighty patients aged between 18 and 80 years diagnosed clinically with XP and the same number of apparently healthy, age- and sex-matched controls were included in the study after
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Ekrikpo, U. E., E. E. Effa, E. E. Akpan, A. S. Obot та S. Kadiri. "Clinical Utility of Urinaryβ2-Microglobulin in Detection of Early Nephropathy in African Diabetes Mellitus Patients". International Journal of Nephrology 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/4093171.

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Background. Studies have indicated that diabetic tubulopathy may occur earlier than glomerulopathy, therefore providing a potential avenue for earlier diagnosis of diabetic nephropathy. Urinary beta-2-microglobulin (β2m) was investigated in this study as a potential biomarker in the detection of early nephropathy in type 2 diabetics.Methods. One hundred and two diabetic subjects and 103 controls that met the inclusion criteria had data (sociodemographic, medical history, physical examination, and laboratory) collected. Urinaryβ2m levels and urinary albumin concentration (UAC) were determined.R
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Abu Baker, Fadi, Amir Mari, Randa Taher, Dorin Nicola, Oren Gal, and Abdel-Rauf Zeina. "The Yield of Colonoscopy in the Evaluation of Constipation: An Age-Based Analysis of Outcome." Journal of Clinical Medicine 13, no. 10 (2024): 2910. http://dx.doi.org/10.3390/jcm13102910.

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Background: Chronic constipation, a prevalent gastrointestinal complaint, exhibits rising incidence and diverse clinical implications, especially among the aging population. This study aims to assess colonoscopy performance in chronic constipation across age groups, comprehensively evaluating diagnostic yield and comparing results with average-risk controls. Methods: A retrospective analysis was conducted on 50,578 colonoscopy procedures performed over 12 years, including 5478 constipated patients. An average-risk control group (n = 4100) was included. Data extracted from electronic medical re
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Amer, Hina, Apriliana E. R. Kartikasari, and Magdalena Plebanski. "Elevated Interleukin-6 Levels in the Circulation and Peritoneal Fluid of Patients with Ovarian Cancer as a Potential Diagnostic Biomarker: A Systematic Review and Meta-Analysis." Journal of Personalized Medicine 11, no. 12 (2021): 1335. http://dx.doi.org/10.3390/jpm11121335.

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Ovarian cancer (OC) is one of the most lethal cancers, largely due to a late diagnosis. This study aimed to provide a comprehensive meta-analysis on the diagnostic performance of IL6 in the blood and ascites separately for advanced and early-stage OC. We included 37 studies with 6948 participants detecting serum or plasma IL6. The plasma/serum IL6 mean level in the late-stage OC was 23.88 pg/mL (95% CI: 13.84–41.23), and the early-stage OC was 16.67 pg/mL (95% CI: 510.06–27.61), significantly higher than the healthy controls at 3.96 pg/mL (95% CI: 2.02–7.73), but not significantly higher than
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Wang, Jen-Chin, Nubar Boghossian, Tsong S. Chang, Allan D. Novetsky, and Allan Astrow. "Enhanced HDAC (Histone Deacetylase) Enzyme Activities in Blood CD 34+ Cells in Patients with Agnogenic Myeloid Metaplasia Are Not Related to Jak 2 Mutation." Blood 106, no. 11 (2005): 4953. http://dx.doi.org/10.1182/blood.v106.11.4953.4953.

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Abstract We have previously reported that HDAC enzyme activities were elevated in patients with agnogenic myeloid metaplasia (AMM) as compared with patients with other myeloproliferative disorders including essential thrombocytosis (ET) and polycythemia vera (PV) and normal volunteer controls (Exp hematol33:1052005). Jak 2 mutations were found in 35–50% patients with AMM. The present study was designed to see if the elevated HDAC activities in AMM are related to JAK 2 mutations. 9 patients of AMM, and 17 of other MPD, and 10 normal volunteer controls were studied. Detection of Jak 2 mutation w
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S. V., Balakrishna, Veerabhadra Goud G. K., and Veluri Ganesh. "A study of serum levels of prostate specific antigen, prostate acid phosphatase in prostate cancer patients and its complications on liver." International Surgery Journal 8, no. 2 (2021): 554. http://dx.doi.org/10.18203/2349-2902.isj20210065.

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Background: The prostate cancer (PC) is most leading disorders in human beings particularly in males. Prostate specific antigen (PSA) and prostate acid phosphatase (PAP) are tumor markers useful for early detection and diagnosis of PC. In prostate cancer patients more prone to liver and bone cancer metastasis because in these patients elevated levels of serum liver function tests (LFT) and these liver enzymes more specific for early detection of pathological changes in liver and bones.Methods: This is the case control study was carried out the association of serum levels of PSA/PAP inpatients
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Ho, A. S., X. Huang, H. Cao, A. C. Koong, and Q. T. Le. "Detection of circulating hypoxia-regulated miR-210 in pancreatic adenocarcinoma patients." Journal of Clinical Oncology 27, no. 15_suppl (2009): 4624. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.4624.

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4624 Background: MicroRNAs (miRs) are small non-coding transcripts involved in many cellular mechanisms, including tumorigenesis. miR-210, in particular, has been shown to be induced by hypoxia, over-expressed in several different cancers, and correlated with adverse outcomes in breast cancer. Moreover, since pancreatic adenocarcinomas have been previously shown to be extremely hypoxic, we hypothesized that miR-210 may be elevated in the plasma of these patients compared to non-cancer controls. Here, we compared the circulating plasma levels of miR-210 in pancreatic cancer patients and control
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Song, Ki-Young, Hyun-Cheal Oh, Kwan-Yuhl Cho, and Hag-Wone Kim. "Initial Rotor Position Detection a PM Synchronous Motor and Speed Control of an Elevator Door." Transactions of the Korean Institute of Power Electronics 18, no. 6 (2013): 556–64. http://dx.doi.org/10.6113/tkpe.2013.18.6.556.

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Eum, Hyukmin, Sukyoon Jang, Heejin Lee, Mignon Park, and Changyong Yoon. "Human Detection and Fuzzy Temperature Control System for Energy Reduction of Cooling Device in Elevator." Journal of Korean Institute of Intelligent Systems 25, no. 2 (2015): 147–54. http://dx.doi.org/10.5391/jkiis.2015.25.2.147.

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Zhang, Zutao, Yipeng Zheng, Hong Xu, and Hengjian Li. "A novel elevator group control algorithm based on binocular-cameras corridor passenger detection and tracking." Multimedia Tools and Applications 74, no. 6 (2013): 1761–75. http://dx.doi.org/10.1007/s11042-013-1716-1.

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Ehrlich, Zvi, Sophia Magen, Heli Alexandroni, Itamar Glik, Sorina Grisaru-Granovsky, and Orna Reichman. "The yield of procalcitonin and Interleukin-6 in predicting intraamniotic infection in the presence of intrapartum fever: A pilot study." PLOS ONE 18, no. 7 (2023): e0288537. http://dx.doi.org/10.1371/journal.pone.0288537.

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Intrapartum fever (IF) accompanied by either maternal or foetal tachycardia, elevated WBC, or purulent discharge is classified as "suspected triple 1", the hallmark of intraamniotic infection (IAI). Poor specificity of the clinical diagnosis of IAI results, in retrospect, in the unnecessary treatment of most parturients and neonates. We studied the yield of specific acute phase reactants (APRs): procalcitonin, CRP, IL-6, in detecting bacterial IAI among parturients classified as "suspected triple 1" (cases) compared to afebrile parturients (controls). Procalcitonin, CRP, and IL-6 were all sign
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Choi, Sunga, Ju Hyun Shin, Yu Ran Lee, et al. "Urinary APE1/Ref-1: A Potential Bladder Cancer Biomarker." Disease Markers 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/7276502.

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Bladder cancer (BCa) is one of the most common urothelial cancers with still noticeable incidence rate. Early detection of BCa is highly correlated with successful therapeutic outcomes. We previously showed that apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) was expressed at an increased level in the serum of BCa patients when compared to the level in healthy controls. In this study, we investigated whether urinary APE1/Ref-1 was also elevated in patients with BCa. In this case-control study, voided urine was collected from 277 subjects including 169 BCa patients and 108 non-
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Liu, Guan-Ting, Chi-Shin Hwang, Chia-Hung Hsieh, et al. "Eosinophil-Derived Neurotoxin Is Elevated in Patients with Amyotrophic Lateral Sclerosis." Mediators of Inflammation 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/421389.

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Background and Objectives. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by loss of motor neurons in the brainstem, motor cortex, and spinal cord. Oxidative stress and neuroinflammation have been implicated in the pathophysiology of ALS. Members of the family of damage-associated molecular patterns, including reactive oxygen species, high-mobility group box 1, and eosinophil-derived neurotoxin (EDN), may participate in pathological conditions. In this study, we aim to discover new biomarker for detecting ALS.Materials and Methods. We examined 44 p
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Setyawan, Ungky A., Susanthy Djajalaksana, Hani Susianti, Fatchiyah Fatchiyah, Arinto Y. P. Wardoyo, and Agustina T. Endharti. "Exhaled volatile organic compound profiles as potential biomarkers for lung cancer: A study of ethanol, formaldehyde, and toluene." Journal of Pharmacy & Pharmacognosy Research 13, no. 4 (2025): 1168–77. https://doi.org/10.56499/jppres24.2208_13.4.1168.

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Context: The early diagnosis and detection of lung cancer are crucial for reducing mortality and morbidity. Recently, the study of biomarkers for diagnosis and early detection has expanded significantly. Several volatile organic compounds (VOCs) found in exhaled breath may serve as valuable indicators for the early detection of lung cancer, which is influenced by pathological factors associated with cancer development. Aims: To create a profile of VOCs in lung cancer patients and healthy controls and to examine the differences in VOC levels among lung cancer patients based on histological type
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Zang, Ying, Shibo Meng, Lian Hu, et al. "Optimization Design and Experimental Testing of a Laser Receiver for Use in a Laser Levelling Control System." Electronics 9, no. 3 (2020): 536. http://dx.doi.org/10.3390/electronics9030536.

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The elevation detection accuracy of the laser receiver in the laser levelling control system directly affects land-levelling operations. To effectively improve the effect of levelling operations and meet the requirements for the accuracy of elevation detection in different industries, this study optimization designed a multilevel adjustable laser receiver. First, we examined the laser signal detection technology and processing circuit, designed the photoelectric conversion array for the detection of the rotating laser, and converted it into a photocurrent signal. We also designed the filter, a
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Janzen, Johan, Thomas G. Elliott, Cedric J. Carter, and Donald E. Brooks. "Detection of red cell aggregation by low shear rate viscometry in whole blood with elevated plasma viscosity." Biorheology: The Official Journal of the International Society of Biorheology 37, no. 3 (2000): 225–37. http://dx.doi.org/10.1177/0006355x2000037003005.

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The viscosity of whole blood measured at low shear rates is determined partly by shear resistance of the red cell aggregates present, stronger aggregation increasing the viscosity in the absence of other changes. Effects of cell deformability can confound interpretation and comparison in terms of aggregation, however, particularly when the plasma viscosity is high. We illustrate the problem with a comparison of hematocrit‐adjusted blood from type 1 diabetes patients and controls in which it is found the apparent and relative viscosities at a true shear rate of 0.20 s $^{-1}$ are lower in the p
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Remmen, Jaap J., Wim R. M. Aengevaeren, Freek W. A. Verheugt, and René W. M. M. Jansen. "Detection of elevated pulmonary capillary wedge pressure in elderly patients with various cardiac disorders by the Valsalva manoeuvre." Clinical Science 111, no. 2 (2006): 153–62. http://dx.doi.org/10.1042/cs20050372.

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In the present study, we assessed whether elevated (≥15 mmHg) PCWP (pulmonary capillary wedge pressure) can be detected using the blood pressure response to the Valsalva manoeuvre in a group of elderly patients with various cardiac disorders, including atrial fibrillation and valvular heart disease, and healthy elderly controls. The Valsalva manoeuvre was performed in 93 patients (71±4 years) and 28 healthy controls (70±4 years) undergoing right-sided cardiac catheterization. Blood pressure was measured non-invasively with Finapres. PPR (pulse pressure ratio), the ratio of minimum pulse pressu
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Anfal Akeel Taha, Hind Salman Jasim, and Wafaa Fadhil Hamad. "Detection of Catalase and 4-Hydroxynonenal as Detective Biomarkers in Iraqi Breast Cancer." Journal of Chemistry Studies 3, no. 2 (2024): 07–13. http://dx.doi.org/10.32996/jcs.2024.3.2.2.

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Breast cancer is the most common malignant tumor among women and a leading cause of cancer-related death. Early diagnosis is critical for improving treatment outcomes. The objective of this study is to determine and examine catalase (CAT) and 4-hydroxynonenal (4-HNE) markers as non-invasive biomarkers for early detection in Iraqi breast cancer. A case-control study of 150 participants was further divided into 75 women with a diagnosis of breast cancer and 75 healthy controls. In the present study, blood samples were collected for the determination of serum CAT and 4-HNE levels using an enzyme-
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Nam, Robert K., Eleftherios P. Diamandis, Ants Toi, et al. "Serum Human Glandular Kallikrein-2 Protease Levels Predict the Presence of Prostate Cancer Among Men With Elevated Prostate-Specific Antigen." Journal of Clinical Oncology 18, no. 5 (2000): 1036. http://dx.doi.org/10.1200/jco.2000.18.5.1036.

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PURPOSE: We hypothesize that serum human glandular kallikrein-2 (hK2) levels predict the presence of prostate cancer among men prescreened by prostate-specific antigen (PSA).PATIENTS AND METHODS: We conducted a cross-sectional study of 324 men who had no history of prostate cancer and who were referred for prostate biopsy. PSA and hK2 levels were measured using specific nonisotopic immunometric techniques. Cases were patients who were diagnosed with adenocarcinoma of the prostate from biopsy, and controls were patients who had no evidence of cancer from biopsy. The odds ratio for detection of
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Mahmoud, Amal, Hanan Mohamed, Amal Abdel Aal, Hala Abdelghafour, and Murad A. Jabir. "Long noncoding RNA HOTAIR and Midkine as biomarkers in thyroid cancer." Egyptian journal of Immunology 30, no. 1 (2023): 125–35. http://dx.doi.org/10.55133/eji.300113.

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Thyroid cancer is the most common endocrine malignancy, and its incidence is increasing. Differentiated thyroid cancer is the most common type and papillary thyroid carcinoma is the most common type of differentiated thyroid cancer. This work aimed to study long noncoding (Lnc) RNA homeobox transcript antisense RNA (HOTAIR) expression in plasma and serum midkine, a heparin binding growth factor, as biomarkers of thyroid cancer. This study included 27 thyroid cancer patients, 29 patients with benign thyroid disease and 26 individuals as normal controls. HOTAIR expression was assessed by real ti
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Wang, Jiangeng, Linglong Zhu, Yonghong Zhang, Wei Huang, Kaida Song, and Feng Tian. "Characterizing Spatiotemporal Patterns of Snowfall in the Kaidu River Basin from 2000–2020 Using MODIS Observations." Remote Sensing 14, no. 22 (2022): 5885. http://dx.doi.org/10.3390/rs14225885.

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Characterizing spatiotemporal patterns of snowfall is essential for understanding cryosphere responses to warming climate stress. The changes in snowfall and topographic controls in mountain regions still need to be clarified. This study proposes a general parsimonious methodology to obtain the frequency of snowfall in mountainous areas. The methodology employed is easily transferable to any other mountain region. Utilizing daily MODIS observations from June 2000 to May 2020 and the snowfall event detection algorithm, we monitored the frequency of snowfall in a long time series in the Kaidu ri
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Younis, Farah Qahtan, Ali Hussein Alwan, and Neihaya Heikmat Zaki. "Using of TLR2 and TLR4 as Biomarker of Sepsis Severity Detection." Al-Mustansiriyah Journal of Science 29, no. 2 (2018): 83. http://dx.doi.org/10.23851/mjs.v29i2.370.

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Our study has been aimed to find the relation between the expression of toll-like receptors 2, 4, level of TNF-α, IL-10 and soluble HLA-DR with the severity bacterial septic syndrome in Iraqi patients. The quantitative real-time PCR technique has been used for measure TLR2 and TLR4 gene expression in whole blood, and ELISA technique has been used for detection of cytokines TNF-α, IL-10 and soluble HLA-DR from 75 septic syndrome cases (nineteen of patients showed symptoms of systemic inflammatory response syndrome (SIRS); twenty-eight patients have sepsis, seventeen patients suffered from sever
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Kacira, Tibet, Rahsan Kemerdere, Pinar Atukeren, et al. "DETECTION OF CASPASE-3, NEURON SPECIFIC ENOLASE, AND HIGH-AENSITIVITY C-REACTIVE PROTEIN LEVELS IN BOTH CEREBROSPINAL FLUID AND SERUM OF PATIENTS AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE." Neurosurgery 60, no. 4 (2007): 674–80. http://dx.doi.org/10.1227/01.neu.0000255394.77538.bb.

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Abstract OBJECTIVE The purpose of this study is to explore whether or not the levels of caspase-3 (Casp3), neuron-specific enolase (NSE), and high-sensitivity C-reactive protein (hsCRP) were elevated in cerebrospinal fluid (CSF) and serum of patients after aneurysmal subarachnoid hemorrhage (SAH). METHODS This prospective clinical study consisted of 20 patients who experienced recent aneurysmal SAH and 15 control patients who experienced hydrocephalus without any other central nervous system disease. CSF and serum samples obtained within the first 3 days, and on the fifth and seventh days of S
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Polin, Richard S., Murad Bavbek, Mark E. Shaffrey, et al. "Detection of soluble E-selectin, ICAM-1, VCAM-1, and L-selectin in the cerebrospinal fluid of patients after subarachnoid hemorrhage." Journal of Neurosurgery 89, no. 4 (1998): 559–67. http://dx.doi.org/10.3171/jns.1998.89.4.0559.

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Object. The goal of this study was to explore whether the levels of soluble adhesion molecules were elevated in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH). This association was suggested by the known inflammatory response in vasospasm and the role of vascular adhesion molecules in regulating leukocytic adhesion to, and migration across, vascular endothelium. Methods. A prospective analysis was performed on CSF samples obtained in 17 patients who had suffered a recent aneurysmal SAH and in 16 control patients by using quantitative enzyme-linked immunosorbent assays for E-sele
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Yang, Libang, Adam Gilbertsen, Blake Jacobson, Robert Kratzke, and Craig A. Henke. "Serum Splicing Factor Proline- and Glutamine-Rich Is a Diagnostic Marker for Non-Small-Cell Lung Cancer and Other Solid Cancers." International Journal of Molecular Sciences 25, no. 16 (2024): 8766. http://dx.doi.org/10.3390/ijms25168766.

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Cancer markers are measurable molecules in blood or tissues that are produced by tumor cells or immune cells in response to cancer progression. They play an important role in clinical diagnosis, prognosis, and therapy monitoring. Splicing factor proline- and glutamine-rich (SFPQ) plays an important role in cancer growth and metastasis. SFPQ is not only more highly expressed in non-small-cell lung cancer (NSCLC) cells than it is in controls, but also highly expressed in cancer cells in patients with other solid cancers. Thus, a new enzyme-linked immunosorbent assay (ELISA) for detecting SFPQ wa
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Jaafar, Salim Shamkhi, Ehab Y. Jabber, Amer Abdul Husain Alwish, Raheem Tuama Obayes Al- Mammori та Hasanain Khaleel Shareef. "THE IMMUNOLOGICAL ROLE OF ANTI-H. PYLORI ANTIBODIES LEVEL, INF-Γ, AND TNF-Α IN A NUMBER OF PATIENTS WITH A TUMOR IN THE DIGESTIVE SYSTEM IN BABYLON GOVERNORATE". International Journal Multidisciplinary (IJMI) 1, № 3 (2024): 168–76. https://doi.org/10.61796/ijmi.v1i3.184.

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General Background: Helicobacter pylori is a well-known bacterium responsible for chronic infections, significantly contributing to gastric and mucosa-associated lymphoid tissue cancers, as well as peptic ulcer disease. Specific Background: The link between H. pylori infection and gastrointestinal (GIT) tumors remains under-explored, particularly concerning immunological parameters. Knowledge Gap: The role of immune markers, such as anti-H. pylori IgG antibodies, TNF-α, and IFN-γ, in distinguishing between malignant and benign GIT tumors is unclear. Aims: This study aimed to assess the relatio
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Myer, Landon, Andrew D. Redd, Elton Mukonda, et al. "Antiretroviral Adherence, Elevated Viral Load, and Drug Resistance Mutations in Human Immunodeficiency Virus–infected Women Initiating Treatment in Pregnancy: A Nested Case-control Study." Clinical Infectious Diseases 70, no. 3 (2019): 501–8. http://dx.doi.org/10.1093/cid/ciz209.

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Abstract Background Elevated viral load (VL) early after antiretroviral therapy (ART) initiation appears frequently in pregnant and postpartum women living with human immunodeficiency virus; however the relative contributions of pre-ART drug resistance mutations (DRMs) vs nonadherence in the etiology of elevated VL are unknown. Methods Within a cohort of women initiating ART during pregnancy in Cape Town, South Africa, we compared women with elevated VL after initial suppression (cases, n = 80) incidence-density matched to women who maintained suppression over time (controls, n = 87). Groups w
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Lu, Miao-Jen, Jose S. Pulido, Colin A. McCannel, et al. "Detection of Elevated Signaling Amino Acids in Human Diabetic Vitreous by Rapid Capillary Electrophoresis." Experimental Diabetes Research 2007 (2007): 1–6. http://dx.doi.org/10.1155/2007/39765.

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Elevated glutamate is implicated in the pathology of PDR. The ability to rapidly assess the glutamate and amino acid content of vitreous provides a more complete picture of the chemical changes occurring at the diabetic retina and may lead to a better understanding of the pathology of PDR. Vitreous humor was collected following vitrectomies of patients with PDR and control conditions of macular hole or epiretinal membrane. A capillary electrophoresis method was developed to quantify glutamate and arginine. The analysis is relatively fast (<6 minutes) and utilizes a poly(ethylene)oxide and s
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Kapp, A., A. Kemper, E. Schöpf, and H. Deicher. "Detection of circulating immune complexes in patients with atopic dermatitis and psoriasis." Acta Dermato-Venereologica 66, no. 2 (1986): 121–26. http://dx.doi.org/10.2340/0001555566121126.

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Sera from 32 patients with atopic dermatitis and 22 patients with psoriasis were examined for the presence of circulating immune complexes (CIC) in comparison to 51 healthy controls using a PEG-precipitation laser nephelometer technique. Different patterns of the precipitated proteins were found in both diseases. In atopic dermatitis C3 and IgG were significantly elevated in CIC. Furthermore, significantly increased amounts of IgE were found in the precipitates. Groups with high and low serum IgE levels showed no significant differences in the quantity of precipitated proteins. Skin involvemen
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Lancaster, J. M., R. A. Sayer, C. Blanchette, et al. "High expression of insulin-like growth factor binding protein–2 messenger RNA in epithelial ovarian cancers produces elevated preoperative serum levels." International Journal of Gynecologic Cancer 16, no. 4 (2006): 1529–35. http://dx.doi.org/10.1136/ijgc-00009577-200607000-00006.

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The molecular etiology of epithelial ovarian cancer remains unclear. Using microarray expression analysis, we recently reported that expression of the insulin-like growth factor binding protein–2 (IGFBP-2) gene is elevated in advanced epithelial ovarian cancers. The aim of this study was to further delineate the role of IGFBP-2 in the pathoetiology of epithelial ovarian cancer and determine if elevated ovarian cancer IGFBP-2 gene expression is reflected in serum. RelativeIGFBP-2expression was measured using quantitative real-time polymerase chain reaction in 113 epithelial ovarian cancers and
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Yang, Shi-Han, Can-Tong Liu, Chao-Qun Hong, et al. "Autoantibodies against p53, MMP-7, and Hsp70 as Potential Biomarkers for Detection of Nonmelanoma Skin Cancers." Disease Markers 2021 (July 10, 2021): 1–10. http://dx.doi.org/10.1155/2021/5592693.

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Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are two predominant histological types of nonmelanoma skin cancer (NMSC), lacking effective early diagnostic markers. In this study, we assessed the diagnostic value of autoantibodies against p53, MMP-7, and Hsp70 in skin SCC and BCC. ELISA was performed to detect levels of autoantibodies in sera from 101 NMSC patients and 102 normal controls, who were recruited from the Cancer Hospital of Shantou University Medical College. A receiver operator characteristic curve was used to evaluate the diagnostic value. The serum levels of autoan
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