Zeitschriftenartikel zum Thema „Dihydroxypyrimidines“
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Powdrill, Megan H., Jerome Deval, Frank Narjes, Raffaele De Francesco und Matthias Götte. „Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines“. Antimicrobial Agents and Chemotherapy 54, Nr. 3 (22.12.2009): 977–83. http://dx.doi.org/10.1128/aac.01216-09.
Der volle Inhalt der QuelleGuo, Di-Liang, Xing-Jie Zhang, Rui-Rui Wang, Yu Zhou, Zeng Li, Jin-Yi Xu, Kai-Xian Chen, Yong-Tang Zheng und Hong Liu. „Structural modifications of 5,6-dihydroxypyrimidines with anti-HIV activity“. Bioorganic & Medicinal Chemistry Letters 22, Nr. 23 (Dezember 2012): 7114–18. http://dx.doi.org/10.1016/j.bmcl.2012.09.070.
Der volle Inhalt der QuelleNovais, H. M., und S. Steenken. „Reactions of oxidizing radicals with 4,6-dihydroxypyrimidines as model compounds for uracil, thymine, and cytosine“. Journal of Physical Chemistry 91, Nr. 2 (Januar 1987): 426–33. http://dx.doi.org/10.1021/j100286a034.
Der volle Inhalt der QuelleTelvekar, Vikas N., und Kavitkumar N. Patel. „Pharmacophore Development and Docking Studies of the HIV-1 Integrase Inhibitors Derived from N-methylpyrimidones, Dihydroxypyrimidines, and Bicyclic Pyrimidinones“. Chemical Biology & Drug Design 78, Nr. 1 (25.05.2011): 150–60. http://dx.doi.org/10.1111/j.1747-0285.2011.01130.x.
Der volle Inhalt der QuelleAstrat'ev, A. A., D. V. Dashko, A. Yu Mershin, A. I. Stepanov und N. A. Urazgil'deev. „ChemInform Abstract: Some Specific Features of Acid Nitration of 2-Substituted 4,6-Dihydroxypyrimidines. Nucleophilic Cleavage of the Nitration Products.“ ChemInform 32, Nr. 51 (23.05.2010): no. http://dx.doi.org/10.1002/chin.200151070.
Der volle Inhalt der QuelleWinterbourn, Christine C., und Rex Munday. „Concerted Action Of Reduced Glutathione And Superoxide Dismutase In Preventing Redox Cycling Of Dihydroxypyrimidines, And Their Role In Antioxidant Defence“. Free Radical Research Communications 8, Nr. 4-6 (Januar 1990): 287–93. http://dx.doi.org/10.3109/10715769009053361.
Der volle Inhalt der QuelleJansa, Petr, Antonín Holý, Martin Dračínský, Viktor Kolman, Zlatko Janeba, Petra Kostecká, Eva Kmoníčková und Zdeněk Zídek. „5-Substituted 2-amino-4,6-dihydroxypyrimidines and 2-amino-4,6-dichloropyrimidines: synthesis and inhibitory effects on immune-activated nitric oxide production“. Medicinal Chemistry Research 23, Nr. 10 (09.05.2014): 4482–90. http://dx.doi.org/10.1007/s00044-014-1018-9.
Der volle Inhalt der QuelleShi, Daqing, Lihui Niu und Qiya Zhuang. „Clean synthesis of pyrido[2,3-d]pyrimidines in aqueous media“. Journal of Chemical Research 2005, Nr. 10 (Oktober 2005): 648–50. http://dx.doi.org/10.3184/030823405774663048.
Der volle Inhalt der QuelleKufelnicki, Aleksander, Jan Jaszczak, Urszula Kalinowska-Lis, Cecylia Wardak und Justyn Ochocki. „Complexes of Uracil (2,4-Dihydroxypyrimidine) Derivatives“. Journal of Solution Chemistry 35, Nr. 5 (Mai 2006): 739–51. http://dx.doi.org/10.1007/s10953-006-9017-1.
Der volle Inhalt der QuelleNovais, H. M., und S. Steenken. „ESR studies of electron and hydrogen adducts of thymine and uracil and their derivatives and of 4,6-dihydroxypyrimidines in aqueous solution. Comparison with data from solid state. The protonation at carbon of the electron adducts“. Journal of the American Chemical Society 108, Nr. 1 (Januar 1986): 1–6. http://dx.doi.org/10.1021/ja00261a001.
Der volle Inhalt der QuelleRostkowska, Hanna, Anna Luchowska, Leszek Lapinski und Maciej J. Nowak. „Photochemical transformations of 4,6-dihydroxypyrimidine and 2-methyl-4,6-dihydroxypyrimidine isolated in low-temperature Ar, Ne and H2 matrices“. Chemical Physics Letters 745 (April 2020): 137263. http://dx.doi.org/10.1016/j.cplett.2020.137263.
Der volle Inhalt der QuelleKeerthi Kumar, Chinnagiri T., Jathi Keshavayya, Tantry N. Rajesh, Sanehalli K. Peethambar und Angadi R. Shoukat Ali. „Synthesis, Characterization, and Biological Activity of 5-Phenyl-1,3,4-thiadiazole-2-amine Incorporated Azo Dye Derivatives“. Organic Chemistry International 2013 (18.08.2013): 1–7. http://dx.doi.org/10.1155/2013/370626.
Der volle Inhalt der QuelleVu, Tuan Q., Nikolai V. Yudin, Alexander A. Kushtaev, Thanh X. Nguyen und Sergey A. Maltsev. „Spectroscopic Study of the Basicity of 4,6-Dihydroxypyrimidine Derivatives“. ACS Omega 6, Nr. 22 (24.05.2021): 14154–63. http://dx.doi.org/10.1021/acsomega.1c00671.
Der volle Inhalt der QuelleKapoor, Bharat, EzzedinA Luhishi, AndrewKK Chung und JakobusC Pauw. „Neurotrophic keratitis in a patient with dihydroxypyrimidine dehydrogenase deficiency“. Indian Journal of Ophthalmology 56, Nr. 4 (2008): 336. http://dx.doi.org/10.4103/0301-4738.41422.
Der volle Inhalt der QuelleMalancona, Savina, Mattia Mori, Paola Fezzardi, Marisabella Santoriello, Andreina Basta, Martina Nibbio, Lesia Kovalenko et al. „5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein“. ACS Medicinal Chemistry Letters 11, Nr. 5 (19.03.2020): 766–72. http://dx.doi.org/10.1021/acsmedchemlett.9b00608.
Der volle Inhalt der QuelleBoyd, Vincent A., John Mason, Parimala Hanumesh, Jeanine Price, Charles J. Russell und Thomas R. Webb. „2-Substituted-4,5-Dihydroxypyrimidine-6-Carboxamide Antiviral Targeted Libraries“. Journal of Combinatorial Chemistry 11, Nr. 6 (09.11.2009): 1100–1104. http://dx.doi.org/10.1021/cc900111u.
Der volle Inhalt der QuelleShennara, Khaled A., Ray J. Butcher und Frederick T. Greenaway. „Crystal structure of tetraaquabis(pyrimidin-1-ium-4,6-diolato-κO4)manganese(II)“. Acta Crystallographica Section E Crystallographic Communications 73, Nr. 4 (31.03.2017): 620–22. http://dx.doi.org/10.1107/s2056989017004649.
Der volle Inhalt der QuelleZhang, Xiao-Min, Hui-Liang Zhou und Qi-Lin Hu. „N-(2-Amino-4,6-dihydroxypyrimidin-5-yl)acetamide dihydrate“. Acta Crystallographica Section E Structure Reports Online 67, Nr. 9 (31.08.2011): o2526. http://dx.doi.org/10.1107/s1600536811034441.
Der volle Inhalt der QuelleMetwally, Mohamed Abbas, und Hassan Ali Etman. „The Synthesis of Indeno[l,2:4,5]pyrimido[l,2-a]benzimidazole-13-ones, Indeno[l,2-b]pyrazolo[4,3-e]pyridine-3,5-dione and Related Compounds*“. Zeitschrift für Naturforschung B 41, Nr. 4 (01.04.1986): 486–88. http://dx.doi.org/10.1515/znb-1986-0413.
Der volle Inhalt der QuelleOtutu, O. J., und A. K. Asiagwu. „Synthesis and Application to Polyester and Nylon 6 Fabrics of Hetaryl Bis-Azo Disperse Dyes Based on 6-Amino-2,4-Dihydroxypyrimidine and 4-Methoxy-2-Nitroaniline Moieties“. Journal of Scientific Research 11, Nr. 2 (01.05.2019): 215–24. http://dx.doi.org/10.3329/jsr.v11i2.38734.
Der volle Inhalt der QuelleTang, Jing, Kasthuraiah Maddali, Yves Pommier, Yuk Y. Sham und Zhengqiang Wang. „Scaffold rearrangement of dihydroxypyrimidine inhibitors of HIV integrase: Docking model revisited“. Bioorganic & Medicinal Chemistry Letters 20, Nr. 11 (Juni 2010): 3275–79. http://dx.doi.org/10.1016/j.bmcl.2010.04.048.
Der volle Inhalt der QuellePace, Paola, M. Emilia Di Francesco, Cristina Gardelli, Steven Harper, Ester Muraglia, Emanuela Nizi, Federica Orvieto et al. „Dihydroxypyrimidine-4-carboxamides as Novel Potent and Selective HIV Integrase Inhibitors“. Journal of Medicinal Chemistry 50, Nr. 9 (Mai 2007): 2225–39. http://dx.doi.org/10.1021/jm070027u.
Der volle Inhalt der QuelleXu, Xue-Jiao, Peng Zheng, Gao-Ping Ren, Mei-Ling Liu, Jun Mu, Jing Guo, Du Cao, Zhao Liu, Hua-Qing Meng und Peng Xie. „2,4-Dihydroxypyrimidine is a potential urinary metabolite biomarker for diagnosing bipolar disorder“. Molecular BioSystems 10, Nr. 4 (2014): 813. http://dx.doi.org/10.1039/c3mb70614a.
Der volle Inhalt der Quellede Melo, Eduardo Borges, und Márcia Miguel Castro Ferreira. „Multivariate QSAR study of 4,5-dihydroxypyrimidine carboxamides as HIV-1 integrase inhibitors“. European Journal of Medicinal Chemistry 44, Nr. 9 (September 2009): 3577–83. http://dx.doi.org/10.1016/j.ejmech.2009.03.001.
Der volle Inhalt der QuelleOfitserova, E. S., A. A. Shklyarenko, I. P. Yakovlev und E. V. Fedorova. „Vilsmeier–Haack formylation of ethyl [(4,6-dihydroxypyrimidin-2-yl)sulfanyl]acetate“. Russian Journal of Organic Chemistry 52, Nr. 9 (September 2016): 1374–76. http://dx.doi.org/10.1134/s1070428016090256.
Der volle Inhalt der QuelleBoyle, Timothy J., Mark A. Rodriguez und Todd M. Alam. „4,6-Dihydroxypyrimidine: a selective bridging ligand for controlled Group IV metal alkoxide structures“. Dalton Transactions, Nr. 24 (2003): 4598. http://dx.doi.org/10.1039/b310087a.
Der volle Inhalt der QuellePacini, Barbara, Salvatore Avolio, Caterina Ercolani, Uwe Koch, Giovanni Migliaccio, Frank Narjes, Laura Pacini, Licia Tomei und Steven Harper. „2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp“. Bioorganic & Medicinal Chemistry Letters 19, Nr. 21 (November 2009): 6245–49. http://dx.doi.org/10.1016/j.bmcl.2009.06.106.
Der volle Inhalt der QuelleMOSKVIN, A. V., N. M. PETROVA, E. A. SEMENOVA, M. SHOPOVA, V. A. GINDIN und B. A. IVIN. „ChemInform Abstract: Azines and Azoles. Part 88. Condensation of 4,6-Dihydroxypyrimidine with Aromatic Aldehydes.“ ChemInform 25, Nr. 27 (19.08.2010): no. http://dx.doi.org/10.1002/chin.199427164.
Der volle Inhalt der QuelleKaren, Pavel, Richard L. Harlow, Zhigang Li, Paul Meenan, Patti A. Parziale, Kirsi Ranta und Teófilo Rojo. „The Crystal Structure of 2-Amino-4,6-dihydroxypyrimidine Determined from Powder X-Ray Synchrotron Diffraction.“ Acta Chemica Scandinavica 52 (1998): 1051–55. http://dx.doi.org/10.3891/acta.chem.scand.52-1051.
Der volle Inhalt der QuelleHe, Tianyu, Tiffany C. Edwards, Jiashu Xie, Hideki Aihara, Robert J. Geraghty und Zhengqiang Wang. „4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease“. Journal of Medicinal Chemistry 65, Nr. 7 (04.04.2022): 5830–49. http://dx.doi.org/10.1021/acs.jmedchem.2c00203.
Der volle Inhalt der QuelleYazdanbakhsh, M. R., H. Yousefi, M. Mamaghani, E. O. Moradi, M. Rassa, H. Pouramir und M. Bagheri. „Synthesis, spectral characterization and antimicrobial activity of some new azo dyes derived from 4,6-dihydroxypyrimidine“. Journal of Molecular Liquids 169 (Mai 2012): 21–26. http://dx.doi.org/10.1016/j.molliq.2012.03.003.
Der volle Inhalt der QuellePetrocchi, Alessia, Uwe Koch, Victor G. Matassa, Barbara Pacini, Kara A. Stillmock und Vincenzo Summa. „From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety“. Bioorganic & Medicinal Chemistry Letters 17, Nr. 2 (Januar 2007): 350–53. http://dx.doi.org/10.1016/j.bmcl.2006.10.054.
Der volle Inhalt der QuelleMuhammad, Munira Taj, Khalid Mohammed Khan, Arshia, Ajmal Khan, Fiza Arshad, Bibi Fatima, M. Iqbal Choudhary, Naima Syed und Syed Tarique Moin. „Syntheses of 4,6-dihydroxypyrimidine diones, their urease inhibition, in vitro, in silico, and kinetic studies“. Bioorganic Chemistry 75 (Dezember 2017): 317–31. http://dx.doi.org/10.1016/j.bioorg.2017.08.018.
Der volle Inhalt der QuelleWang, Kuan, Jian-Gang Chen, Bozhou Wang, Yueping Ji, Fengyi Liu, Zhao-Tie Liu, Wenliang Wang, Zhong-Wen Liu, Zhengping Hao und Jian Lu. „Insight into the acidic group-induced nitration mechanism of 2-methyl-4,6-dihydroxypyrimidine (MDP) with nitronium“. RSC Advances 6, Nr. 83 (2016): 80145–57. http://dx.doi.org/10.1039/c6ra18842g.
Der volle Inhalt der QuelleKrishnakumar, V., und N. Prabavathi. „DFT simulations and vibrational analysis of FTIR and FT-Raman spectra of 2-amino-4,6-dihydroxypyrimidine“. Journal of Raman Spectroscopy 39, Nr. 5 (13.02.2008): 679–84. http://dx.doi.org/10.1002/jrs.1916.
Der volle Inhalt der QuelleHoti, Ramiz, Hamit Ismaili, Veprim Thaçi, Gjyle Mulliqi-Osmani, Malësore Pllana-Zeqiri und Agon Bytyqi. „An Efficient Synthesis of Novel 3-[(Heteroaryl-2-ylimino)-methyl]-4-hydroxy-chromen-2-ones and Analogue of Tetrazole Derivatives and Their Antibacterial Activity“. Molbank 2021, Nr. 4 (02.12.2021): M1303. http://dx.doi.org/10.3390/m1303.
Der volle Inhalt der QuelleXiao, Bo, und et al. „Crystal structure of aqua-[(2,2’-bipyridine)]-[(2,4-dihydroxypyrimidine- 5-carboxylato)] perchloratocopper(II), Cu(H2O)(C10H8N2)(C5H3N2O4)(ClO4), C15H13ClCuN4O9“. Zeitschrift für Kristallographie - New Crystal Structures 227, Nr. 3 (September 2012): 365–66. http://dx.doi.org/10.1524/ncrs.2012.0176.
Der volle Inhalt der QuelleStansfield, Ian, Salvatore Avolio, Stefania Colarusso, Nadia Gennari, Frank Narjes, Barbara Pacini, Simona Ponzi und Steven Harper. „Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid“. Bioorganic & Medicinal Chemistry Letters 14, Nr. 20 (Oktober 2004): 5085–88. http://dx.doi.org/10.1016/j.bmcl.2004.07.075.
Der volle Inhalt der QuelleSumma, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Cristina Gardelli, Ester Muraglia, Michael Rowley, Odalys Gonzalez Paz, Ralph Laufer, Edith Monteagudo und Paola Pace. „4,5-Dihydroxypyrimidine Carboxamides andN-Alkyl-5-hydroxypyrimidinone Carboxamides Are Potent, Selective HIV Integrase Inhibitors with Good Pharmacokinetic Profiles in Preclinical Species“. Journal of Medicinal Chemistry 49, Nr. 23 (November 2006): 6646–49. http://dx.doi.org/10.1021/jm060854f.
Der volle Inhalt der QuelleLi, Xianghong, Shuduan Deng, Xiaoguang Xie und Guanben Du. „Synergistic inhibition effect of 5-aminotetrazole and 4,6-dihydroxypyrimidine on the corrosion of cold rolled steel in H 3 PO 4 solution“. Materials Chemistry and Physics 181 (September 2016): 33–46. http://dx.doi.org/10.1016/j.matchemphys.2016.06.031.
Der volle Inhalt der QuelleSumma, Vincenzo, Alessia Petrocchi, Victor G. Matassa, Marina Taliani, Ralph Laufer, Raffaele De Francesco, Sergio Altamura und Paola Pace. „HCV NS5b RNA-Dependent RNA Polymerase Inhibitors: From α,γ-Diketoacids to 4,5-Dihydroxypyrimidine- or 3-Methyl-5- hydroxypyrimidinonecarboxylic Acids. Design and Synthesis“. Journal of Medicinal Chemistry 47, Nr. 22 (Oktober 2004): 5336–39. http://dx.doi.org/10.1021/jm0494669.
Der volle Inhalt der QuelleCushman, Mark, Jeffrey T. Mihalic, Klaus Kis und Adelbert Bacher. „Design and synthesis of 6-(6-D-ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic acid, a potent inhibitor of lumazine synthase“. Bioorganic & Medicinal Chemistry Letters 9, Nr. 1 (Januar 1999): 39–42. http://dx.doi.org/10.1016/s0960-894x(98)00687-8.
Der volle Inhalt der QuelleLi, Xin-yang, Jing-wei Liang, Kamara Mohamed O, Ting-jian Zhang, Guo-Qing Lu und Fan-hao Meng. „Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs“. European Journal of Medicinal Chemistry 154 (Juni 2018): 267–79. http://dx.doi.org/10.1016/j.ejmech.2018.05.020.
Der volle Inhalt der QuelleCushman, Mark, Jeffrey T. Mihalic, Klaus Kis und Adelbert Bacher. „ChemInform Abstract: Design and Synthesis of 6-(6-D-Ribitylamino-2,4-dihydroxypyrimidin-5-yl)-1-hexylphosphonic Acid, a Potent Inhibitor of Lumazine Synthase.“ ChemInform 30, Nr. 19 (16.06.2010): no. http://dx.doi.org/10.1002/chin.199919169.
Der volle Inhalt der QuelleKobayashi, Satoshi, Makoto Ueno, Gakuto Ogawa, Akira Fukutomi, Masafumi Ikeda, Takuji Okusaka, Tosiya Sato et al. „Impact of renal function on the efficacy and safety of S-1 with concurrent radiotherapy for locally advanced pancreatic cancer.“ Journal of Clinical Oncology 37, Nr. 4_suppl (01.02.2019): 301. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.301.
Der volle Inhalt der QuelleFestus, Chioma, Anthony C. Ekennia, Aderoju A. Osowole, Lukman O. Olasunkanmi, Damian C. Onwudiwe und Oguejiofo T. Ujam. „Synthesis, experimental and theoretical characterization, and antimicrobial studies of some Fe(II), Co(II), and Ni(II) complexes of 2-(4,6-dihydroxypyrimidin-2-ylamino)naphthalene-1,4-dione“. Research on Chemical Intermediates 44, Nr. 10 (13.06.2018): 5857–77. http://dx.doi.org/10.1007/s11164-018-3460-7.
Der volle Inhalt der QuelleNOVAIS, H. M., und S. STEENKEN. „ChemInform Abstract: Reactions of Oxidizing Radicals with 4,6-Dihydroxypyrimidines as Model Compounds for Uracil, Thymine, and Cytosine.“ ChemInform 18, Nr. 21 (26.05.1987). http://dx.doi.org/10.1002/chin.198721086.
Der volle Inhalt der QuelleNOVAIS, H. M., und S. STEENKEN. „ChemInform Abstract: ESR Studies of Electron and Hydrogen Adducts of Thymine and Uracil and Their Derivatives and of 4,6-Dihydroxypyrimidines in Aqueous Solution.“ Chemischer Informationsdienst 17, Nr. 19 (13.05.1986). http://dx.doi.org/10.1002/chin.198619054.
Der volle Inhalt der Quelle-, V. M. Sherekar, N. S. Padole - und K. P. Kakade -. „Synthesis, Characterization and Biological Evaluation of 6-(5-Chloro-8-Hydroxynapthalene-2-yl)-4(4-Hydroxyphenyl)-4-5-Dihydroxypyrimidin-2(1h)-One“. International Journal For Multidisciplinary Research 4, Nr. 6 (28.12.2022). http://dx.doi.org/10.36948/ijfmr.2022.v04i06.1240.
Der volle Inhalt der QuelleBeylkin, Diane, Gyanendra Kumar, Wei Zhou, Jaehyeon Park, Trushar Jeevan, Chandraiah Lagisetti, Rhodri Harfoot, Richard J. Webby, Stephen W. White und Thomas R. Webb. „Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease“. Scientific Reports 7, Nr. 1 (Dezember 2017). http://dx.doi.org/10.1038/s41598-017-17419-6.
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