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Zeitschriftenartikel zum Thema „DiCre“

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Veröffentlicht am 25. Mai 2024

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1

Jullien, Nicolas, Isabelle Goddard, Samia Selmi-Ruby, Jean-Luc Fina, Harold Cremer und Jean-Paul Herman. „Conditional Transgenesis Using Dimerizable Cre (DiCre)“. PLoS ONE 2, Nr. 12 (26.12.2007): e1355. http://dx.doi.org/10.1371/journal.pone.0001355.

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2

Santos, Renato E. R. S., Gabriel L. A. Silva, Elaine V. Santos, Samuel M. Duncan, Jeremy C. Mottram, Jeziel D. Damasceno und Luiz R. O. Tosi. „A DiCre recombinase-based system for inducible expression in Leishmania major“. Molecular and Biochemical Parasitology 216 (September 2017): 45–48. http://dx.doi.org/10.1016/j.molbiopara.2017.06.006.

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3

Duncan, Samuel M., Elmarie Myburgh, Cintia Philipon, Elaine Brown, Markus Meissner, James Brewer und Jeremy C. Mottram. „Conditional gene deletion with DiCre demonstrates an essential role for CRK3 inLeishmania mexicanacell cycle regulation“. Molecular Microbiology 100, Nr. 6 (13.04.2016): 931–44. http://dx.doi.org/10.1111/mmi.13375.

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4

Koussis, Konstantinos, Chrislaine Withers-Martinez, David A. Baker und Michael J. Blackman. „Simultaneous multiple allelic replacement in the malaria parasite enables dissection of PKG function“. Life Science Alliance 3, Nr. 4 (16.03.2020): e201900626. http://dx.doi.org/10.26508/lsa.201900626.

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Over recent years, a plethora of new genetic tools has transformed conditional engineering of the malaria parasite genome, allowing functional dissection of essential genes in the asexual and sexual blood stages that cause pathology or are required for disease transmission, respectively. Important challenges remain, including the desirability to complement conditional mutants with a correctly regulated second gene copy to confirm that observed phenotypes are due solely to loss of gene function and to analyse structure–function relationships. To meet this challenge, here we combine the dimerisable Cre (DiCre) system with the use of multiple lox sites to simultaneously generate multiple recombination events of the same gene. We focused on the Plasmodium falciparum cGMP-dependent protein kinase (PKG), creating in parallel conditional disruption of the gene plus up to two allelic replacements. We use the approach to demonstrate that PKG has no scaffolding or adaptor role in intraerythrocytic development, acting solely at merozoite egress. We also show that a phosphorylation-deficient PKG is functionally incompetent. Our method provides valuable new tools for analysis of gene function in the malaria parasite.

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Tang, Hengli. „Zika Says No Dice to Dicer“. Cell Stem Cell 27, Nr. 4 (Oktober 2020): 503–4. http://dx.doi.org/10.1016/j.stem.2020.09.005.

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6

Fernandes, Priyanka, Manon Loubens, Rémi Le Borgne, Carine Marinach, Beatrice Ardin, Sylvie Briquet, Laetitia Vincensini et al. „The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts“. PLOS Pathogens 18, Nr. 6 (22.06.2022): e1010643. http://dx.doi.org/10.1371/journal.ppat.1010643.

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Plasmodium sporozoites that are transmitted by blood-feeding female Anopheles mosquitoes invade hepatocytes for an initial round of intracellular replication, leading to the release of merozoites that invade and multiply within red blood cells. Sporozoites and merozoites share a number of proteins that are expressed by both stages, including the Apical Membrane Antigen 1 (AMA1) and the Rhoptry Neck Proteins (RONs). Although AMA1 and RONs are essential for merozoite invasion of erythrocytes during asexual blood stage replication of the parasite, their function in sporozoites was still unclear. Here we show that AMA1 interacts with RONs in mature sporozoites. By using DiCre-mediated conditional gene deletion in P. berghei, we demonstrate that loss of AMA1, RON2 or RON4 in sporozoites impairs colonization of the mosquito salivary glands and invasion of mammalian hepatocytes, without affecting transcellular parasite migration. Three-dimensional electron microscopy data showed that sporozoites enter salivary gland cells through a ring-like structure and by forming a transient vacuole. The absence of a functional AMA1-RON complex led to an altered morphology of the entry junction, associated with epithelial cell damage. Our data establish that AMA1 and RONs facilitate host cell invasion across Plasmodium invasive stages, and suggest that sporozoites use the AMA1-RON complex to efficiently and safely enter the mosquito salivary glands to ensure successful parasite transmission. These results open up the possibility of targeting the AMA1-RON complex for transmission-blocking antimalarial strategies.

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Burkard, Thorsten. „Schrieb Cato dicae und faciae oder dice und facie?“ Hermes 146, Nr. 2 (2018): 208. http://dx.doi.org/10.25162/hermes-2018-0017.

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Davalos, Veronica, und Manel Esteller. „Rolling the Dice to Discover the Role of DICER in Tumorigenesis“. Cancer Cell 21, Nr. 6 (Juni 2012): 717–19. http://dx.doi.org/10.1016/j.ccr.2012.05.030.

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Paoli, Matilde. „La Crusca risponde ogni tre per due o ogni due per tre?“ XII, 2020/1 (gennaio-marzo) 12, Nr. 1 (13.03.2020): 58–62. http://dx.doi.org/10.35948/2532-9006/2020.3271.

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Molti lettori ci scrivono, specialmente dal Nord Italia, ma anche da Firenze, Roma e Sassari, chiedendo chiarimenti su un modo di dire “numerico”: per significare che qualcosa accade molto spesso si dice che avviene ogni tre per due oppure ogni due per tre? Qual è l’origine di questa espressione? È un modo di dire diffuso da sempre su tutto il territorio nazionale o si è originato in una particolare area?

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Wang, Qian, Yan Xue, Laixing Zhang, Zhenhui Zhong, Suhua Feng, Changshi Wang, Lifan Xiao et al. „Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation“. Science 374, Nr. 6571 (26.11.2021): 1152–57. http://dx.doi.org/10.1126/science.abl4546.

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Ready to dice In the biogenesis of small RNAs, the Dicer family endonucleases act as a molecular ruler to cut the substrate RNA into defined lengths. Wang et al . report a structure of the dicing-competent state of plant DICER LIKE PROTEIN 3 (DCL3) in complex with a pre–small interfering RNA (pre-siRNA). Toward one end of the pre-siRNA, DCL3 uses a positively charged pocket and an aromatic cap to specifically recognize the 5′-phosphorylated adenosine of the guide strand and the 3′ overhang of the complementary strand, respectively. On the other end, the paired ribonuclease III domains of DCL3 cut both strands of the RNA, determining the precise length of the product small RNA. —DJ

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Kidd, Stephen E. „Greek Dicing, Astragaloi and the ‘Euripides’ Throw“. Journal of Hellenic Studies 137 (2017): 112–18. http://dx.doi.org/10.1017/s0075426917000088.

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AbstractGreeks, unlike Romans, gambled with five not four knucklebones (astragaloi) in their dice games. As Pollux explains, the high number of an individual knucklebone was sometimes eight rather than six, and so when a dicer rolled ‘all eights’ they attained a sum of 40. This roll was called the ‘Euripides’. The confusion about this throw is due to a report found in Byzantine sources and attributed to Suetonius, where it is claimed that dicers of Greek antiquity used four knucklebones. Suetonius may have confused the Roman custom with the Greek one, but there are good grounds for questioning whether the report is from ‘Suetonius’ at all. Elsewhere ‘Suetonius’ reports that Greeks played with three rather than two cubic dice, but such a report cannot have been made before the seventh century AD.

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Juniah und Praty Milindasari. „Hubungan Pemberian MP-ASI Dini Dengan Kejadian Diare Pada Bayi Usia 0-6 Bulan : Literature Review“. Jurnal Keperawatan Bunda Delima 6, Nr. 1 (29.02.2024): 29–38. http://dx.doi.org/10.59030/jkbd.v6i1.97.

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Pemberian makanan pendamping ASI yang terlalu dini atau sebelum usia 6 bulan akan mempermudah masuknya berbagai jenis kuman pada tubuh bayi terutama jika makanan tersebut tidak disajikan secara higienis. Hal ini dikarenakan sistem imun yang kurang sempurna pada bayi yang berusia kurang dari 6 bulan. Sehingga sering terjadi gangguan pada sistem pencernaan dan menyebabkan resiko terjadinya diare lebih besar dibandingkan dengan bayi yang menerima makanan pendamping ASI (MP-ASI) setelah usia 6 bulan. Tujuan Penelitian ini bertujuan untuk menganalisa hubungan pemberian MP-ASI dini dengan kejadian dire pada bayi usia 0-6 bulan berdasarkan literature review. Desain penelitian yang digunakan dalam karya tulis ilmiah ini adalah studi literature revie. Hasil literatur review ini menunjukkan bahwa dari 5 jurnal menunjukkan bahwa terdapat hubungan pemberian MP-ASI dengan kejadian diare pada bayi usia 0-6 bulan. Jurnal 1 menggunakan uji Chi-square, jurnal 2 menggunakan uji Spearman, jurnal 3 menggunakan uji regresi linier sederhana, jurnal 4 menggunakan uji Chi-square, jurnal 5 menggunakan uji Chi-square. Kesimpulan yang diperoleh adalah adanya hubungan antara pemberian Makanan Pendamping ASI (MP-ASI) dini dengan kejadian diare pada bayi usia 0-6 bulan.

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Gilbert, Paul. „Saying the Unsayable in Phenomenology?“ Revista Portuguesa de Filosofia 76, Nr. 2-3 (31.07.2020): 729–60. http://dx.doi.org/10.17990/rpf/2020_76_2_0729.

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Fierens, Christian. „Que veut dire « dire » ?“ Essaim 28, Nr. 1 (2012): 133. http://dx.doi.org/10.3917/ess.028.0133.

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Rittaud-Hutinet, Chantal. „Comment dire sans dire?“ Langues & Parole 7 (26.12.2022): 93–111. http://dx.doi.org/10.5565/rev/languesparole.119.

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Lorsque, pour faire part de ses opinions, de ses goûts, de ses états d’âme, de ses aversions, l’énonciateur emploie un discours ou un méta-discours non-verbal, cela signifie qu’il le fait avec des intonations expressives. Celles-ci remplacent les mots correspondants. Elles sont d’une grande richesse et d’une grande variété. La composante vocale donne à l’énonciateur la capacité de faire avancer très rapidement le développement de son thème, et elle lui offre de nombreuses facilités pour des stratégies discursives, comme : gauchir le sens dénoté de ses mots, le renforcer, le contester, l’infirmer, en réduire la portée, ménager sa face et celle de l’allocutaire. Il transmet alors à la dérobée jugement, moquerie, insinuation, réserve, surprise, suggestion, espoir, réprobation, conseil, appréciation, remontrance, colère, conviction, demande de connivence, compassion... Avec des exemples (conversations non préparées, film) où l’acoustique est la seule marque qui guide le destinataire vers l’interprétation du non-dit de l’énonciateur, est analysé le signifié pragmatique et le signifiant des unités linguistiques de l’intonation expressive que sont les signes vocaux. Une comparaison est ensuite établie entre les façons dont deux méthodes de fle traitent l’acte de langage non verbal, et leurs rapports avec la réalité du phénomène. Puis sont exposés rapidement le cadre et les procédures de la recherche en phonopragmatique.

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Fathi, Jean. „La maison du diacre Fatḥī“. Journal of Eastern Christian Studies 74, Nr. 1-2 (24.08.2022): 73–201. http://dx.doi.org/10.1163/17831520-20220001.

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Résumé Aux XVIIIe et XIXe siècles, la maison du diacre Amīršāh Fatḥī de Diyarbakır se trouvait à l’épicentre des événements concernant la communauté ancienne-syrienne d’héritage syriaque dans l’Empire ottoman, ayant un mot à dire dans l’élection des patriarches à Mardin et les tentatives d’union entre l’Église syrienne-orthodoxe d’Antioche et l’Église catholique. Les Cogias Fatḥī dérivaient leur autorité des moyens générés par leur maison de négoce, qui participait dans les années 1700 au commerce international entre la Perse, les territoires ottomans et l’Europe. Leur histoire est contée à partir d’une vingtaine d’archives en Orient et Occident.

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Tworak, Aleksander, Anna Urbanowicz, Jan Podkowinski und Marek Figlerowicz. „Animal Dicer and plant Dicer-like proteins“. BioTechnologia 1 (2013): 22–26. http://dx.doi.org/10.5114/bta.2013.46429.

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Revel, Judith, und Azucena G. Blanco. „« Michel Foucault : dire politique, dire littéraire, dire philosophique ». Introduction“. Revue internationale de philosophie 292, Nr. 2 (2020): 7. http://dx.doi.org/10.3917/rip.292.0007.

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Schneider, Massimo, und Alessandro Musetti. „Recensioni. La mente del corpo: intenzionalità e inconscio della coscienza / Costruire l'adolescenza Tra immedesimazione e bisogni“. Ricerca Psicoanalitica 26, Nr. 3 (31.12.2015): 135–41. http://dx.doi.org/10.4081/rp.2015.351.

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Nella favola del vestito nuovo dell'imperatore basta la voce di un bambino per far sì che tutti arrivino ad ammettere ciò che già vedono ma non possono dire nemmeno a loro stessi, ovvero che il monarca in realtà è nudo. La storia non dice che cosa succede poi, ma è assai probabile che quest'ultimo, non potendo più reggere la finzione, abbandoni la chimera di un vestito bellissimo ma inesistente, mettendosi alla ricerca di sarti più onesti dei precedenti per farsi confezionare vestiti magari meno splendenti di quelli immaginati ma più aderenti alla realtà dei fatti.

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Plant, David R., und Gordon S. Lynch. „Depolarization-induced contraction and SR function in mechanically skinned muscle fibers from dystrophic mdx mice“. American Journal of Physiology-Cell Physiology 285, Nr. 3 (September 2003): C522—C528. http://dx.doi.org/10.1152/ajpcell.00369.2002.

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Dystrophin is absent in muscle fibers of patients with Duchenne muscular dystrophy (DMD) and in muscle fibers from the mdx mouse, an animal model of DMD. Disrupted excitation-contraction (E-C) coupling has been postulated to be a functional consequence of the lack of dystrophin, although the evidence for this is not entirely clear. We used mechanically skinned fibers (with a sealed transverse tubular system) prepared from fast extensor digitorum longus muscles of wild-type control and dystrophic mdx mice to test the hypothesis that dystrophin deficiency would affect the depolarization-induced contractile response (DICR) and sarcoplasmic reticulum (SR) function. DICR was similar in muscle fibers from mdx and control mice, indicating normal voltage regulation of Ca2+ release. Nevertheless, rundown of DICR (<50% of initial) was reached more rapidly in fibers from mdx than control mice [control: 32 ± 5 depolarizations ( n = 14 fibers) vs. mdx: 18 ± 1 depolarizations ( n = 7) before rundown, P < 0.05]. The repriming rate for DICRs was decreased in fibers from mdx mice, with lower submaximal DICR observed after 5, 10, and 20 s of repriming compared with fibers from control mice ( P < 0.05). SR Ca2+ reloading was not different in fibers from control and mdx mice, and no difference was observed in SR Ca2+ leak. Caffeine (2–7 mM)-induced contraction was diminished in fibers from mdx mice compared with control ( P < 0.05), indicating depressed SR Ca2+ release channel activity. Our findings indicate that fast fibers from mdx mice exhibit some impairment in the events mediating E-C coupling and SR Ca2+ release channel activity.

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Kumar, Bijender, Mayra Garcia, Guido Marcucci und Ching-Cheng Chen. „Dicer Ablations in Bone Marrow Niche Impair Hematopoietic Progenitor/Stem Cells and Induce Myelodysplasia in Young Mice but Are Dispensable for Adult Hematopoiesis“. Blood 126, Nr. 23 (03.12.2015): 1196. http://dx.doi.org/10.1182/blood.v126.23.1196.1196.

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Abstract MicroRNAs (miRNAs) regulate hematopoietic cell fate and their global down-regulation by Dicer1 deletion promotes tumorigenesis in a cancer-cell-autonomous manner (Kumar M.S. et al, 2007). Raajimakers MH et al. (2010) using neonatal Osterix specific dicer deletion showed altered hematopoiesis and developed myelodysplasia. However, there is no study illustrating the role of the ablation of bone marrow (BM) niche specific miRNA processing machinery in the adult mice. Since expression and functions of different mesenchymal and osteoprogenitors vary from embryonic development to adulthood, studying the dicer ablation in adult mice may provide more insight about the role of miRNA processing in adult mice niche. Here we investigate whether adult Osterix expressing cells play a similar role in the HSC niche compared to fetal Osterix expressing cells. We crossed Osx-GFP-tTA-Cre recombinase mice with mice with floxed Dicer1 allele. Crossing generated Osx- GFP-tTA-Cre+Dicerfl/+ (OCDfl/+control) and Osx-GFP- tTA-Cre+ Dicerfl/fl (OCDfl/fl mutant) mice. Osx-GFP-tTA-Cre expression was either activated during embryonic development (young dicer KO) or suppressed using tetracycline until mice were 6 weeks of age (adult dicer KO). We found young dicer KO mice had reduced weight (p=0.0031), leukopenia, anemia, reduced mature CD19+B220- B lymphocytes (p=0.0034) and increased CD11b+Gr- monocytes and CD11b+Gr+ neutrophils (p=0.02 and p=0.04 respectively) in peripheral blood compared to OCDfl/+ control aged littler mates. The leucocytes and platelets showed dysplastic changes suggestive of myelodysplasia and had extra-medullary hematopoiesis. Adult dice KO, on the other hand, show no leukemia development 6 months after Cre activation. The number of BM hematopoietic progenitors (Lin-Sca1+ c-Kit+ cells, LSK) and long term hematopoietic stem cells (LT-HSCs, LSK CD150+CD48+ cells) in young dicer KO mice were significantly reduced compared to age matched control (OCDfl/+ control) mice. We observed increased Annexin V positive LSK, LT-HSCs and megakaryocytes erythroid progenitors (MEP) in the young dicer KO mice indicating increased apoptosis. Adult dicer KO mice didn't have significant changes in apoptosis in different hematopoietic progenitors. In young dicer KO mice, BM derived LSK and LT-HSCs showed increased cycling (SG2M phase, p=0.0133) and less quiescenece (Go phase, p=0.013). However LT-HSC from adult dicer KO didn't show any difference in cell cycling (p=0.18 and 0.09 respectively). Together these results indicate that while Osterix expressing cells in fetal and young mice give rise to a variety of HSC niche supporting cells the adult expression is limited to more mature osteoblast that are not absolutely essential for HSC maintenance. Our study provides the rationale for further exploration of the complexity in hierarchy of activity within niche constituting mesenchymal stroma progenitors and their role in different developmental stages to maintain hematopoiesis. Disclosures No relevant conflicts of interest to declare.

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McLoughlin, Mary. „Dire ou ne pas dire“. Essaim 42, Nr. 1 (2019): 7. http://dx.doi.org/10.3917/ess.042.0007.

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Petit, François-Xavier. „Dire et ne pas dire“. Hypothèses 16, Nr. 1 (2013): 191. http://dx.doi.org/10.3917/hyp.121.0191.

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Jarauta, Francisco. „“Verdad dice quien dice sombra”“. Sociología Histórica 12, Nr. 1 (28.07.2023): 220–26. http://dx.doi.org/10.6018/sh.578601.

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Asche, Stefan. „Dicke Backen“. VDI nachrichten 74, Nr. 30-31 (2020): 40. http://dx.doi.org/10.51202/0042-1758-2020-30-31-40-6.

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Pionke, Stefanie. „Dicke Finanzspritze“. agrarzeitung 76, Nr. 11 (2021): 5. http://dx.doi.org/10.51202/1869-9707-2021-11-005.

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Roses, Mor M., und Emanuele G. Dalla Torre. „Dicke model“. PLOS ONE 15, Nr. 9 (04.09.2020): e0235197. http://dx.doi.org/10.1371/journal.pone.0235197.

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Zampetaki, Anna, und Manuel Mayr. „Sweet Dicer“. Circulation Research 117, Nr. 2 (03.07.2015): 116–18. http://dx.doi.org/10.1161/circresaha.117.306817.

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Heinrichs, Arianne. „Dispensable Dicer“. Nature Reviews Molecular Cell Biology 11, Nr. 7 (Juli 2010): 461. http://dx.doi.org/10.1038/nrm2932.

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VanHook, A. M. „Dicer Switch“. Science Signaling 7, Nr. 356 (16.12.2014): ec348-ec348. http://dx.doi.org/10.1126/scisignal.aaa4715.

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Joyce, Lillian B. „Dirce Disrobed“. Classical Antiquity 20, Nr. 2 (01.10.2001): 221–38. http://dx.doi.org/10.1525/ca.2001.20.2.221.

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The Punishment of Dirce was a theme that intrigued both artists and patrons of the Roman period. It appeared in diverse locations and media, notably as a wall painting in the House of the Vettii in Pompeii and the Toro Farnese once displayed in the Baths of Caracalla in Rome. In all representations, Dirce struggles with the bull that will trample her to death. Traditional studies of this imagery have focused on the formal characteristics of these representations, studying issues of workshop practice and the relationship between originals and copies. Scholars seldom analyze the meaning of the myth in depth. While most studies note that Dirce often appears in the guise of a maenad, they dismiss this observation. Additionally, it is rarely noted that Dirce's semi-nudity has any role in this story. In fact, her nudity is highly significant, for it was not part of the literary accounts. This study offers a fresh interpretation of Dirce's punishment considering the function of gender. Using literary sources such as Euripides, Plautus, Lucian, and Petronius, as well as visual images in a variety of media including wall painting, sculpture, gems, medals, and lamps, it is argued that artists and patrons combined maenadism and nudity to portray Dirce as a specifically female social transgressor. As a semi-nude maenad, the queen abandons accepted female decorum. These attributes allow the viewer readily to identify Dirce as guilty of hubris against family and society.

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Didiek Hardiyanto Soegiantoro, Vanessa Sasmytha Djera Pay, Wirany Djangga Uma, Pilar Tesalonika Wahyukurnia und Jacques Jericho Joschka Jose. „PENINGKATAN PENGETAHUAN MASYARAKAT TERHADAP DIARE DAN SWAMEDIKASI DIARE“. J-ABDI: Jurnal Pengabdian kepada Masyarakat 1, Nr. 10 (01.03.2022): 2717–26. http://dx.doi.org/10.53625/jabdi.v1i10.1621.

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Kasus diare di Indonesia masih sangat besar, menurut data 10,2% penduduk mengalami diare. Kematian anak balita akibat diare di dunia masih sangat tinggi. Pemahaman masyarakat tentang keberbahayaan diare terutama pada balita masih sangat kurang, demikian pula pola hidup bersih dan sehat masih menjadi permasalahan bagi sebagian besar masyarakat Indonesia. Kegiatan ini bertujuan untuk meningkatkan pengetahuan masyarakat tentang diare, penyebab, keberbahayaannya, serta cara penanganannya menggunakan bahan alam maupun obat-obatan. Metode yang dilakukan adalah dengan penyuluhan secara online dalam bentuk webinar menggunakan media zoom. Peserta webinar ini adalah masyarakat umum tanpa batas usia, gender, dan wilayah geografis. Jumlah peserta yang mengikuti kegiatan penyuluhan sebanyak 48 orang dari berbagai wilayah di Indonesia dan sebagian besar dari usia remaja sampai dewasa. Hasil yang dicapai dalam kegiatan penyuluhan adalah terjadi peningkatan pengetahuan masyarakat terhadap diare dan cara penanganannya dengan bahan alam maupu obat-obatan. Evaluasi pengetahuan masyarakat didapatkan dengan melihat kenaikan nilai-rata-rata terhadap uji sebelum dan sesudah kegiatan.

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de Saint-Exupéry, Patrick. „Dire“. Inflexions N° 14, Nr. 2 (2010): 49. http://dx.doi.org/10.3917/infle.014.0049.

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Djaouti, Damien. „DICE“. International Journal of Game-Based Learning 10, Nr. 2 (April 2020): 39–53. http://dx.doi.org/10.4018/ijgbl.2020040103.

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This article deals with serious game design methods. More specifically, it focuses on the following question: is there any universal series of steps to design a serious game? Or is the availability of several different design methods unavoidable? To try to answer this question, we will study a corpus of ten design methods suited to Serious Games. Most of these theoretical tools are coming from or aimed to industry professionals. This literary review will allow us to perform a comparative analysis over the various steps used by these methods, in order to build a generic model for the design process of Serious Games: the Design / Imagine / Create / Evaluate (D.I.C.E.) model.

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Rezig, El Kindi, Anshul Bhandari, Anna Fariha, Benjamin Price, Allan Vanterpool, Vijay Gadepally und Michael Stonebraker. „DICE“. Proceedings of the VLDB Endowment 14, Nr. 12 (Juli 2021): 2819–22. http://dx.doi.org/10.14778/3476311.3476353.

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In order to conduct analytical tasks, data scientists often need to find relevant data from an avalanche of sources (e.g., data lakes, large organizational databases). This effort is typically made in an ad hoc, non-systematic manner, which makes it a daunting endeavour. Current data discovery systems typically require the users to find relevant tables manually, usually by issuing multiple queries (e.g., using SQL). However, expressing such queries is nontrivial, as it requires knowledge of the underlying structure (schema) of the data organization in advance. This issue is further exacerbated when data resides in data lakes, where there is no predefined schema that data must conform to. On the other hand, data scientists can often come up with a few example records of interest quickly. Motivated by this observation, we developed DICE---a human-in-the-loop system for <u>D</u>ata d<u>I</u>s<u>C</u>overy by <u>E</u>xample---that takes user-provided example records as input and returns more records that satisfy the user intent. DICE's key idea is to synthesize a SQL query that captures the user intent, specified via examples. To this end, DICE follows a three-step process: (1) DICE first discovers a few candidate queries by finding join paths across tables within the data lake. (2) Then DICE consults with the user for validation by presenting a few records to them, and, thus, eliminating spurious queries. (3) Based on the user feedback, DICE refines the search and repeats the process until the user is satisfied with the results. We will demonstrate how DICE can help in data discovery through an interactive, example-based interaction.

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Carlotti, Jan-Mari, und Élisabeth Cestor. „Dire“. La pensée de midi N° 28, Nr. 2 (09.04.2009): 159–65. http://dx.doi.org/10.3917/lpm.028.0159.

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Franckel, Jean-Jacques. „Dire“. Langue française 186, Nr. 2 (2015): 87. http://dx.doi.org/10.3917/lf.186.0087.

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Young, Vinson, Prashant J. Nair und Moinuddin K. Qureshi. „DICE“. ACM SIGARCH Computer Architecture News 45, Nr. 2 (14.09.2017): 627–38. http://dx.doi.org/10.1145/3140659.3080243.

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Peter, Marcus E. „DICE“. Cell Cycle 13, Nr. 9 (April 2014): 1373–78. http://dx.doi.org/10.4161/cc.28673.

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Zhong, Fangcheng, George Alex Koulieris, George Drettakis, Martin S. Banks, Mathieu Chambe, Frédo Durand und Rafał K. Mantiuk. „DiCE“. ACM Transactions on Graphics 38, Nr. 6 (08.11.2019): 1–13. http://dx.doi.org/10.1145/3355089.3356552.

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Panwar, Gaurav, Reza Tourani, Travis Mick, Abderrahmen Mtibaa und Satyajayant Misra. „DICE“. ACM SIGCOMM Computer Communication Review 47, Nr. 5 (25.10.2017): 67–72. http://dx.doi.org/10.1145/3155055.3155066.

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Gună, Ştefan, Luca Mottola und Gian Pietro Picco. „DICE“. ACM Transactions on Sensor Networks 10, Nr. 4 (Juni 2014): 1–34. http://dx.doi.org/10.1145/2509434.

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Granier, François. „Dire son travail, dire le travail“. Sociologies pratiques 37, Nr. 2 (2018): 145. http://dx.doi.org/10.3917/sopr.037.0145.

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Dayan-Herzbrun, Sonia. „Dire, ne pas dire les sexualités“. Journal des anthropologues, Nr. 82-83 (01.12.2000): 179–94. http://dx.doi.org/10.4000/jda.3338.

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Lenoble-Pinson, Michèle. „DIRE ET SE DIRE AU FÉMININ“. International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique 19, Nr. 1 (24.02.2006): 9–24. http://dx.doi.org/10.1007/s11196-005-9008-3.

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Santambrogio, Marco. „Un pensiero di troppo“. SOCIETÀ DEGLI INDIVIDUI (LA), Nr. 38 (September 2010): 153–61. http://dx.doi.org/10.3280/las2010-038013.

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Esseri umani, paesi, paesaggi, sono alcuni dei maggiori oggetti del nostro amore. Lo stesso si puň dire di certi ideali, per esempio dell'ideale di giustizia. Harry Frankfurt ha dedicato parte della sua riflessione alla fenomenologia dell'amore, ma dice relativamente poco riguardo alla possibilitÀ che sorgano conflitti tra i nostri oggetti d'amore - specialmente quando č in gioco la giustizia. Questo saggio prende spunto, ancora una volta, dal caso dell'uomo su una barca troppo piccola per trasportare tre persone, che si trova a dover decidere chi salvare tra le due che sono con lui, una delle quali č sua moglie. Il problema č piů arduo di quanto pensi Frankfurt.

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Farinelli, Patrizia. „"[...] in un giardino d'armida : Il racconto d'autunno di Landolfi. Esempio di metamorfosi novecentesca del fantastico“. Acta Neophilologica 42, Nr. 1-2 (30.12.2009): 153–61. http://dx.doi.org/10.4312/an.42.1-2.153-161.

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Tommaso Landolfi (1908-1979) e uno dei narratori italiani novecenteschi piu coscienti dei limiti del linguaggio; la sua poetica poggia, infatti, sul postulato che ogni narrare commette un tradimento nei confronti del suo referente per la natura stessa della parola, che muta l'oggetto del dire, mentre lo dice, e non c'e scritto in cui egli non ritomi su questo punto. II suo opus, le cui prime prove risalgono alla seconda meta degli anni Trenta, e rappresentato soprattutto da racconti brevi, costruiti intomo a storie d'impianto non verosimile, e da opere di genere diaristico o piuttosto pseudo diaristico, considerato che il discorso autobiografico vi risulta sempre intersecato da elementi di finzione.

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Garraway, Barry M. „The Dicke model in quantum optics: Dicke model revisited“. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 369, Nr. 1939 (28.03.2011): 1137–55. http://dx.doi.org/10.1098/rsta.2010.0333.

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A short review of recent developments of the Dicke model in quantum optics is presented. The focus is on the model in a cavity at zero temperature and in the rotating wave approximation. Topics discussed include spectroscopic structures, the giant quantum oscillator, entanglement and phase transitions.

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Kouba, Annick. „La contrainte à dire, dire la contrainte“. Chimères 72, Nr. 1 (2010): 115. http://dx.doi.org/10.3917/chime.072.0115.

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Yacine, Tassadit. „Dire ou ne pas dire les homosexualités“. Tumultes 41, Nr. 2 (2013): 49. http://dx.doi.org/10.3917/tumu.041.0049.

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