Thematische Bibliographien / Diarrhea – therapy

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  2. Dissertationen
  3. Bücher
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  5. Konferenzberichte
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Auswahl der wissenschaftlichen Literatur zum Thema „Diarrhea – therapy“

Autor: Grafiati
Veröffentlicht am 30. Juni 2021
Zuletzt aktualisiert am 1. Februar 2022

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Zeitschriftenartikel zum Thema "Diarrhea – therapy"

1

Ismail, Rudi, Achiriul Bakri, Mohammad Nazir und Ryanto Haridawati. „Antibiotic Therapy for Invasive Bacterial Diarrhea“. Paediatrica Indonesiana 34, Nr. 1-2 (01.11.2018): 26–37. http://dx.doi.org/10.14238/pi34.1-2.1994.26-37.

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To evaluate the effectiveness of the standard practice of antibiotic prescribing in diarrheal diseases (DD) at Palembang General Hospital, we performed this single blind clinical trial. Subjects were children with DD, without E. histolytica.. or G. Iamblia in their stool, 6 to 59 months of age, seen at the OPD from May 20, 1991 until March 31, 1992. Antibiotic treatment (AT) was given to the treated group (n=289), and was withheld from the control group (n=298). The effectiveness of antibiotic treatment was measured by rate of reconsultation, need for subsequent AT, duration of diarrhea, vomiting, and fever as measured by home visitors. The treated group has a significantly shorter duration of diarrhea and a significant difference in the need for additional AT. Subjects whose diarrhea persist more than 7 days were significant statistically only in bloody diarrhea and in subjects whose fecal leukocytes were more than 9 per high power field. Profuse diarrhea and mother's anxiety were the main reasons for further consultation, which were strikingly greater in control than in treated group. Mothers seeked reconsultation 12.5 times more often for bloody diarrhea and 19.5 times for mucoid diarrhea plus fever. This study reconfirmed that AT in DD shortens the duration of diarrhea, diminishes the rate of reconsultation, and need for subsequent antibiotics in bloody and mucoid diarrhea.
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Suardiana, I. Kadek, und A. A. Gede Rai Yadnya Putra. „REVIEW OF SOME TRADITIONAL HERBALS INCLUDED IN USADA TENUNG TANYA LARA AS DIARRHEA THERAPY AGENTS“. Journal of Pharmaceutical Science and Application 2, Nr. 2 (01.12.2020): 36. http://dx.doi.org/10.24843/jpsa.2020.v02.i02.p01.

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Background: Diarrhea is one of the most extraordinary diseases in the world, with a number of 2.195 children die every day, and 801.000 children die from diarrhea every year. Diarrhea therapy has actually been conducted by society, but the use of synthetic drugs is limited for diarrhea cases since it will trigger undesirable effects, such as abdominal pain and resistance to pathogenic bacteria. Bali, with its unique culture, has Usada Tenung Tanya Lara, which contains procedures for treating diarrhea using plants. Objective: This work aimed to review traditional medicine, which is written in Usada Tenung Tanya Lara, that has been intensified nowadays and can be an alternative in the treatment of diarrhea. Methods: This article review using a primary data source and secondary data sources. Result: Some of the plants that have been collected have anti-diarrheal activity in the usada Tenung Tanya Lara are turmeric (Curcuma longa), banana (Musa paradisiaca) and ancak (Ficus religiosa). These three plants mostly have anti-diarrheal activity by inhibiting and killing pathogenic bacteria that cause diarrhea, such as Shigella dysenteriae, Escherichia coli, and Vibrio cholerae. Aside from being antibacterial, all three plants also have several mechanisms to cure diarrhea. Conclusion: It was revealed that turmeric, banana, and ancak leaf could act as agents of diarrhea therapy with their respective mechanisms of actions. Keywords: Diarrhea, Usada Tenung Tanya Lara, Curcuma longa, Musa paradisiaca, Ficus religiosa.
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Santos-Ocampo, Perla D., Alicia O. Caspellan, Ninofar Z. Porras, Maridel Borja, Carmelita Belmonte-Cuyugan und Celerino Bernas. „Diarrhoeal Disorders in the Philippines“. Paediatrica Indonesiana 18, Nr. 11-12 (13.06.2017): 299. http://dx.doi.org/10.14238/pi18.11-12.1978.299-318.

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Lactose malabsorption exists in almost half of Filipinos, however, diarrhea due to lactose malabsorption found in association with diarrheas is very commonly encountered. This paper mentions solutions to the problem of diarrheal disorders, including early and accurate diagnosis and management. Specific management stresses both oral and intravenous rehydration, dietary management, correction of protein-energy malnutrition and antibiotic therapy, as necessary.
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Shakhmardanov, Murad Z., und V. V. Nikiforov. „ETIOTROPIC THERAPY OF INFECTIOUS DIARRHEA“. Epidemiology and Infectious Diseases (Russian Journal) 23, Nr. 6 (15.12.2018): 301–7. http://dx.doi.org/10.18821/1560-9529-2018-23-6-301-307.

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The issues of etiotropic therapy of infectious diarrhea require a differentiated approach not only depending on the etiological factor, but also on the type of diarrhea caused by the location of the pathological process. Infectious diarrhea occur in the form of three main types: secretory, osmotic, inflammatory (invasive). Secretory and osmotic type of diarrhea are found in infectious gastroenteritis. In the mechanisms of elimination of infectious gastroenteritis pathogens, the following factors play a leading role: the destructive effect on pathogens in the lumen of the small intestine of trypsin, chemotrypsin and acid duodenal content entering the small intestine; the «killer» action of interepithelial large granular lymphocytes (M-cells) on pathogens; the increase in resistance of the small intestine epithelium under the influence of M-cell cytokines; the difficulty of intercellular distribution of pathogens due to faster than in the gut, small intestine epithelial cell renewal; microbial antagonism of representatives of normal intestinal microflora. The appointment of etiotropic agents in cases of infectious gastroenteritis, at least, suppresses the manifestations of microbial antagonism on the part of representatives of the normal intestinal microflora, creating prerequisites for the delay of the pathogen in the body. The inflammatory type of diarrhoea occurs when invasion of pathogens to the mucosal lining of the colon, with subsequent development of the destructive changes and the possibility of further translocation. Obstacles to adhesion, penetration and intercellular spread of invasive pathogens in the colon mucosa is much less than in the small intestine. Pathogens of the same genera, species and serological variants (e.g. Salmonella, Campylobacter) can cause both secretory and invasive types of diarrhea. However, the appointment of antibacterial therapy will depend on the location of the pathological process. When gastroenteritis etiotropic therapy in most cases is impractical. In the presence of clinical manifestations of colitis, involving the implementation of invasive properties of the causative agent, the appointment of etiotropic treatment is justified.
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Shakhmardanov, Murad Z., und V. V. Nikiforov. „ETIOTROPIC THERAPY OF INFECTIOUS DIARRHEA“. Epidemiology and Infectious Diseases (Russian Journal) 23, Nr. 6 (15.12.2018): 301–7. http://dx.doi.org/10.18821/1560-9529-2019-23-6-301-307.

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The issues of etiotropic therapy of infectious diarrhea require a differentiated approach not only depending on the etiological factor, but also on the type of diarrhea caused by the location of the pathological process. Infectious diarrhea occur in the form of three main types: secretory, osmotic, inflammatory (invasive). Secretory and osmotic type of diarrhea are found in infectious gastroenteritis. In the mechanisms of elimination of infectious gastroenteritis pathogens, the following factors play a leading role: the destructive effect on pathogens in the lumen of the small intestine of trypsin, chemotrypsin and acid duodenal content entering the small intestine; the «killer» action of interepithelial large granular lymphocytes (M-cells) on pathogens; the increase in resistance of the small intestine epithelium under the influence of M-cell cytokines; the difficulty of intercellular distribution of pathogens due to faster than in the gut, small intestine epithelial cell renewal; microbial antagonism of representatives of normal intestinal microflora. The appointment of etiotropic agents in cases of infectious gastroenteritis, at least, suppresses the manifestations of microbial antagonism on the part of representatives of the normal intestinal microflora, creating prerequisites for the delay of the pathogen in the body. The inflammatory type of diarrhoea occurs when invasion of pathogens to the mucosal lining of the colon, with subsequent development of the destructive changes and the possibility of further translocation. Obstacles to adhesion, penetration and intercellular spread of invasive pathogens in the colon mucosa is much less than in the small intestine. Pathogens of the same genera, species and serological variants (e.g. Salmonella, Campylobacter) can cause both secretory and invasive types of diarrhea. However, the appointment of antibacterial therapy will depend on the location of the pathological process. When gastroenteritis etiotropic therapy in most cases is impractical. In the presence of clinical manifestations of colitis, involving the implementation of invasive properties of the causative agent, the appointment of etiotropic treatment is justified.
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Ford, Edward G., L. Michelle Jennings und Richard J. Andrassy. „Therapy for intractable diarrhea“. Journal of Pediatrics 110, Nr. 5 (Mai 1987): 815–16. http://dx.doi.org/10.1016/s0022-3476(87)80033-1.

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Okunribido, Osibamke O., William R. Brieger, O. O. Omotade und A. A. Adeyemo. „Cultural Perceptions of Diarrhea and Illness Management Choices among Yoruba Mothers in Oyo State, Nigeria“. International Quarterly of Community Health Education 17, Nr. 3 (Oktober 1997): 309–18. http://dx.doi.org/10.2190/w07w-b4fx-tex7-wc3k.

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Home management of childhood illness is a norm throughout most of the world. Decisions about treatment are influenced by cultural perceptions of the illness, and diarrheal illnesses are no exception. A group of 473 mothers and their pre-school age children in rural communities outside Ibadan metropolis in Nigeria were followed over a two-month period. Data were collected on actual diarrhea illness episodes: mothers' names for these illnesses were recorded, and reported treatment actions were noted. Six major ethno-medical diarrheal illnesses were identified and were grouped broadly into watery diarrheas and dysentery-like diarrheas. Although few (40%) women used home-made sugar-salt solution (SSS) in case management, those who labeled their child's illness as a watery diarrhea were more likely to use SSS. Modern and herbal medicines were commonly and equally applied to both groups of diarrheal illnesses. While very few mothers reported decreased fluid intake by their children, many said the child had reduced appetite, especially if the child had a watery diarrhea. The findings indicate that twelve years after the national Oral Rehydration Therapy (ORT) Program was launched, few mothers practice the recommended actions of giving SSS, increasing food intake and avoiding drugs. Lack of attention to studies that describe the cultural basis for mothers' decisions could be part of the reason why the ORT has not been more successful.
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Chauhan, Aman, Reema Anil Patel, Laura Luque, Holly Chitwood, Fariha Siddiqui, Zachary Tarter, Katherine Mitchell, James Cloud, Rachel C. Miller und Lowell Brian Anthony. „Amino acid mixture (enterade) as a new approach to reducing cancer therapy-induced gastrointestinal toxicity: A retrospective study.“ Journal of Clinical Oncology 38, Nr. 15_suppl (20.05.2020): e24107-e24107. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e24107.

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e24107 Background: Gastrointestinal toxicity is a common side effect of cancer therapy. Pre-clinical studies using a proprietary mixture of amino acids, demonstrated a reduction in mucositis and gastrointestinal toxicity following irradiation via tightening of the mucosal barrier, increasing proliferation of crypt cells, increasing villous height and increasing absorption of fluid, electrolytes and nutrients. A novel 5-amino acid mixture “enterade” was previously evaluated in a Phase II clinical trial for anti-diarrheal effects in post bone marrow transplant patients at Dana Farber Cancer Institute (NCT02919670). Signs of anti-diarrheal efficacy were found in treatment-compliant patients.Enterade is currently being tested in two prospective Phase II studies (NCT03722511 and NCT04073017) in neuroendocrine tumor patients with quality of life limiting diarrhea. We conducted a pilot study to evaluate early antidiarrheal signals in oncologic treatment-induced diarrhea. Methods: An IRB-approved retrospective chart review was conducted at Markey Cancer Center between Sept 2019 and Dec 2019. Medical records were retrospectively reviewed for all solid tumor patients who received enterade for chemotherapy or immunotherapy-induced diarrhea. Patients were instructed to consume one 8-oz bottle of enterade twice a day for at least one week in addition to standard of care antidiarrheal medications. Results: A total of 46 patients were offered enterade. Antidiarrheal efficacy data was available on 17 patients. 11 were female and the mean age of the cohort was 64 years. Six out of 17 patients had a previous history of bowel resection. Four patients had immune checkpoint induced colitis. Three patients developed diarrhea from TKI use and rest were on cytotoxic chemotherapy at the time of the diarrheal episode. Eighty-eight percent (15/17) of patients reported a reduction in diarrhea frequency after consuming enterade. On average, patients noticed an improvement in diarrhea frequency after 3.6 days of enterade consumption, with 86% (13/15) of responders reporting at least 50% reduction in diarrhea frequency. Conclusions: Patient-reported diarrheal improvement after enterade consumption is consistent with pre-clinical data. Results suggest the amino acid mixture may alleviate symptoms of cancer therapy-induced gastrointestinal toxicity (i.e. diarrhea). A prospective clinical trial is warranted to substantiate the observed improvement in chemotherapy and immunotherapy induced diarrhea.
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Fanny, Kesatrianita Mawarni, Wahyu Damayanti und Mohammad Juffrie. „Effect of adding tyndallized probiotics to the World Health Organization standard therapy for acute diarrhea in children“. Paediatrica Indonesiana 52, Nr. 2 (30.04.2012): 91. http://dx.doi.org/10.14238/pi52.2.2012.91-94.

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Background Diarrhea is the major cause of morbidity and mortalityin children. Probiotics can decrease the frequency and durationof diarrhea. There are two types of probiotics, live and tyndallized.Tyndallized probiotics have been stetilized, so they are unable to produceactive metabolites, but may have an effect on human immunity.Objective To evaluate the effectiveness of supplementing WHOstandard therapy with tyndallized probiotics in children withacute, watery diarrhea.Methods We performed a randomized, single-blind, controlledtrial in children aged 3-60 months who were diagnosed with acute,watery diarrhea at Gunungsitoh General Hospital, Nias, NorthSumatera. Subjects were collected by consecutive sampling byway of parent interviews.Results One hundred subjects with acute, watery diarrhea weredivided into 2 groups of 50. One group was treated with onlyWHO standard therapy for acute, watery diarrhea. The othergroup was treated by WHO standard therapy with the additionof tyndallized probiotics. There were no significant differences inbasic characteristics between the two groups. Diarrheal durationfor the group receiving WHO standard therapy only was 3.95 ±1.3 days, while that of the group receiving both WHO standardtherapy and tyndallized probiotics was 4.6 ± 2.3 days (P > 0.05).Diarrheal frequency on the fifth day in the WHO standard therapygroup was 1.90 ± 0.99 times per day, while that of the tyndalhzedprobiotic group was 1.56 ± 0.67 times per day (P > 0.05).Conclusion There were no significant differences between WHOstandard therapy alone and WHO standard therapy with the additionof tyndallized probiotics for decreasing the duration and frequency ofdiarrhea in children. [Paediatr lndones. 2012;52:91-4].
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Saad Mohmed, Eiman Ahmed, und Mohammed AbdallaIbrahim Abdalla. „Awareness and Knowledge of Mothers Regarding Home Management of Diarrheal Disease for Children Less Than Five“. International Journal of Healthcare and Medical Sciences, Nr. 73 (11.07.2021): 58–62. http://dx.doi.org/10.32861/ijhms.73.58.62.

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Background: Diarrhea is the major cause of morbidity and mortality among children less than 5 years of age. Adequate rehydration therapy is the most important aspect of management. Home-based Oral Rehydration Therapy (ORT) prevents morbidity and mortality. In this study, our objective was to assess the awareness and knowledge of mothers regarding home management of the diarrheal disease for children less than five years in Gaffer Ibnauf specialized children’s hospital. Methods: This study was descriptive cross-sectional in gaffer ibnauf specialized children hospital. A questionnaire was provided to all the mothers admitted by children under five. in gastroenteritis word. Results: A total of 50 mothers60% of mothers have an aware understanding of the term childhood diarrhea. 52% of mothers were aware of signs of diarrhea. 48.0% of mothers aware of the severe symptoms noticed in children with diarrhea. 40.0% of mothers identify the mode of diarrhea spread, and more than halve the mothers had poor knowledge. 52.0% of mothers are aware of the danger of diarrhea. 42.0% of respondents were aware that dehydration is associated with acute loss of water and salt from the body. 52.0% of responders had good knowledge about the management of diarrhea. 64.0% of the respondents were aware of the composition of oral rehydration therapy. 48.0% of the respondents had knowledge of how to avoid some diets (like fat and fiber) in order to prevent diarrhea. Conclusions:- The study concluded that mothers had good knowledge about definition, signs, symptoms, main danger of diarrhea, the composition of ORT, importance of fluid and breastfeed continuation, and they had poor knowledge about the diet control types of diarrheal diseases and mode of its transmission.
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Dissertationen zum Thema "Diarrhea – therapy"

1

Casswall, Thomas. „Passive immunisation as therapy for gastrointestinal infections in children /“. Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3862-8/.

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Rau, Anna Katharina. „Cryptosporidiosis in pre-weaned calves : observations in Germany and Portugal“. Master's thesis, Universidade Técnica de Lisboa. Faculdade de Medicina Veterinária, 2012. http://hdl.handle.net/10400.5/4010.

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Dissertação de Mestrado Integrado em Medicina Veterinária
A criptosporidiose é uma das mais importantes causas de diarreia neonatal bovina, sendo uma potencial ameaça à produção e uma importante causa de prejuízos económicos. Vitelos recém-nascidos e até ao desmame são especialmente susceptíveis à infecção e desenvolvimento de sinais clínicos pelo parasita protozoário Cryptosporidium parvum, já que nascem quase completamente desprovidos de mecanismos de imunidade naturais. Este parasita é considerado existente mundialmente, ubiquitário, sem especificidade ao hospedeiro e oportunista. Os efeitos da infecção, nomeadamente a diarreia, desidratação e desequilibrios electrolíticos, juntamente com acidose metabólica, enfraquecem os animais e podem originar elevados níveis de morbilidade e mortalidade moderada, especialmente quando associado a outros agentes. Actualmente não é conhecido nenhum tratamento específico completamente eficaz no combate à criptosporidiose bovina. O tratamento baseia-se na terapia de suporte por meio de fluidoterapia oral e endovenosa. Medidas preventivas assentes em melhorias de higiene e administração correcta de colostro são consideradas as mais importantes. O potencial zoonótico do parasita, especialmente em indivíduos imuno-deprimidos, levanta preocupações de saúde pública. No presente trabalho, foram elaborados 2 estudos clínicos, tentando confirmar a existência, prevalência e sinais clínicos de criptosporidiose em regiões na Alemanha e em Portugal. Na Universidade Justus-Liebig em Giessen, Alemanha, 35 vitelos foram examinados tendo em conta os seus sinais clínicos. Vinte e dois dos animais examinados demonstraram sinais de diarreia e, entre estes, 36% excretavam oocistos. Seguiu-se um exame mais detalhado dos animais infectados, incluindo o estudo dos sinais clínicos e dos valores laboratoriais. Os sinais clínicos e laboratoriais detectados confirmaram os esperados (característicos da criptosporidiose), incluindo diarreia fluida, desidratação, fraqueza e hipotermia; acidose metabólica, aumento dos níveis de lactato e hiponatremia. Todos os vitelos recuperaram após fluidoterapia, controlo da acidose e antibioterapia. Lactato de halofuginona foi administrado em alguns animais mas não demonstrou efeitos evidentes. Em Portugal, 30 vitelos foram examinados numa exploração de engorda na área do Ribatejo, considerando os seus sinais clínicos e a presença de oocistos após análise pela técnica de Ziehl-Neelsen modificada. A prevalência foi elevada (43%). Os sinais clínicos variaram e a excreção de oocistos nem sempre estava acompanhada de diarreia (portadores assintomáticos). A evolução de quinze vitelos re-examinados variou, evidenciando por um lado a existência do carácter autolimitante (3 vitelos melhoraram) e por outro um possível aumento da mortalidade (2 vitelos morreram) associados à doença.
ABSTRACT - Cryptosporidiosis in pre-weaned calves – Observations in Germany and Portugal - Cryptosporidiosis is one of the most important causes of bovine neonatal diarrhea, being considered an important threat to bovine production and a cause of economical losses. Pre-weaned, neonatal calves are particularly prone to the infection and development of clinical signs due to the protozoan parasite Cryptosporidium parvum, as they are born almost completely deprived of natural immunity. This parasite is a worldwide existing, ubiquitous, non host specific and opportunistic agent of diarrhea. Dehydration and electrolyte imbalances, coupled with metabolic acidosis, weaken the animals and may cause high morbidity rates and moderate mortality, especially when occurring in combination with other infectious agents. No completely effective specific treatment for calf cryptosporidiosis is known to this date. Treatment is mainly based on supportive care by oral and intravenous fluid therapy. Prevention by hygiene measures, correct colostral administration and management seem to be most important. Public health concerns arise due to its zoonotic potential, especially in immune compromised individuals. In the present dissertation, two case studies were developed, trying to confirm the existence, prevalence and clinical signs of cryptosporidiosis in Germany and Portugal. In the Clinics for Obstetrics, Gynecology and Andrology with veterinary ambulance from the Justus Liebig University Giessen, Germany, 35 calves were examined for their clinical signs. 22 of the examined calves showed diarrhea and of these, 36% were positively excreting oocysts. A more detailed examination of the infected calves was performed and clinical signs and laboratory values studied. Detected clinical and laboratory signs could be confirmed by the expected (characteristic signs of cryptosporidiosis), including watery to thin mushy diarrhea, dehydration, weakness and hypothermia; metabolic acidosis, increased levels of lactate and hypernatremia. All calves recovered after alkalinizing fluid therapy and antibiotherapy. Halofuginone lactate was administered to some animals but it was not clear if it caused a major improvement in the recovery. In Portugal, 30 calves were examined in a fattening unit in the Ribatejo area concerning their clinical signs and presence of oocysts after modified Ziehl-Neelsen technique. Prevalence was high with 43% of animals showing oocysts in the faeces. Clinical signs varied and excretion was not always accompanied by diarrhea (assympthomatic carriers). Fifteen of the examined calves were reexamined one month later. Results varied greatly, evidencing on one hand the self-limiting character of the disease (3 calves improved) and, on the other hand, the possible connection of the disease to an increased mortality (2 calves died).
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Silva, Alessandra Costa da. „SoluÃÃes de reidrataÃÃo oral no modelo de desnutriÃÃo e diarreia induzida pela toxina do cÃlera em camundongos: corregulaÃÃo gÃnica e expressÃo das proteÃnas transportadoras SGTL-1, PEPT-1, CAT-1 e SN2“. Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=13508.

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nÃo hÃ
As taxas de morbimortalidade se elevam quando a diarreia està associada à desnutriÃÃo. Entretanto, os mecanismos pelos quais as deficiÃncias nutricionais afetam o intestino sÃo em grande parte desconhecidos. O objetivo desse trabalho foi avaliar alteraÃÃes morfomÃtricas, nas proteÃnas transportadoras de substratos e no transporte intestinal de eletrÃlitos e Ãgua em modelo de desnutriÃÃo em camundongos. Objetivamos ainda, analisar o efeito da toxina do cÃlera (TC) associada ou nÃo à desnutriÃÃo, sobre as proteÃnas transportadoras de substratos, sobre o transporte hidroeletrolÃtico em camundongos e por fim, avaliamos os efeitos de soluÃÃes de reidrataÃÃo oral (SRO) da OMS (SGli) e modificadas com glutamina (SGln), alanil-glutamina(SAla-Gln) e arginina (SArg) nesse transporte. Camundongos (n=20) receberam por 7 dias uma raÃÃo deficiente em proteÃnas, gorduras e minerais (DBR). Segmentos de Ãleo foram obtidos antes e no 7 dia da dieta, para estudos de morfometria, imunohistoquÃmica para as proteÃnas: SGTL-1, PepT-1, CAT-1 e SN-2 e avaliaÃÃo por RT-qPCR da expressÃo RNAm dessas proteÃnas transportadoras. O modelo de perfusÃo intestinal por 75 min em camundongos (n=6) foi utilizado para avaliar o transporte intestinal de Ãgua e eletrÃlitos e para avaliar o papel de soluÃÃes de reidrataÃÃo oral em camundongos nutridos e desnutridos expostos ou nÃo à toxina do cÃlera (1Âg/ml). Animais desnutridos apresentaram perda ponderal, atrofia dos vilos e reduÃÃo na expressÃo por imunofluorescÃncia da SGTL-1. A desnutriÃÃo causou ainda reduÃÃo na expressÃo do RNAm da SGTL-1 e PEPT-1 e aumento na expressÃo do RNAm para o SN-2 no ileo de camundongos. No modelo de perfusÃo intestinal, a desnutriÃÃo aguda aumentou a secreÃÃo intestinal de eletrÃlitos e Ãgua. A TC aumentou a secreÃÃo de eletrÃlitos e Ãgua em modelo de perfusÃo intestinal de camundongos. A TC aumentou a transcriÃÃo para o RNAm dos transportadores intestinais SGTL-1, PEPT-1 e CAT-1, mas nÃo aumentou a transcriÃÃo para o SN-2. As soluÃÃes de reidrataÃÃo com glicose (SGli), glutamina (SGln), alanil-glutamina (SAla-Gln) e arginina (SArg) diminuÃram a secreÃÃo de eletrÃlitos induzida pela TC. Apenas a SGln nÃo conseguiu diminuir significativamente a secreÃÃo de Ãgua induzida pela TC. Apenas a SGli reduziu a secreÃÃo de Ãgua induzida pela TC. SGli, SAla-Gln e SArg, mas nÃo SGln, diminuÃram a secreÃÃo de sÃdio e cloreto induzida pela TC. A desnutriÃÃo associada à diarreia pela TC causou reduÃÃo na transcriÃÃo para o RNAm dos transportadores intestinais SGTL-1, PEPT-1, CAT-1 e SN-2. A desnutriÃÃo associada à TC aumentou a secreÃÃo de Ãgua quando comparado ao grupo nutrido exposto à TC. SGli, SAla-Gln e SArg, mas nÃo SGln, diminuÃram a secreÃÃo de Ãgua induzida pela desnutriÃÃo associada à TC. Todas as soluÃÃes diminuÃram a secreÃÃo de sÃdio e cloreto induzida pela desnutriÃÃo associada à TC.
The morbidity and mortality rates rise when diarrhea is associated with malnutrition. However, the mechanisms by which nutritional deficiencies affect the gut are largely unknown. The aim of this study was to evaluate morphological changes in transport proteins and substrates in intestinal transport of electrolytes and water in malnutrition model in mice. We aim to further analyze the effect of cholera toxin (CT) with or without malnutrition on the carrier proteins substrates on electrolyte transport in mice and finally, we evaluate the effects of oral rehydration solutions (ORS) of OMS (SGli) e modified with glutamine (SGln), alanyl-glutamine (SAla-Gln) and arginine (SArg) in this transport. Mice (n=20) received for 7 days a diet deficient in protein, fat and minerals (DBR). Segments of ileum were obtained before and on day 7 of the diet, for studies of morphology, immunohistochemistry for proteins: SGTL-1, PEPT-1, CAT-1 and SN-2 and evaluated by RT-qPCR of mRNA expression of these transport proteins. The model of intestinal perfusion for 75 min in mice (n=6) was used to evaluate the intestinal transport of water and electrolytes and to evaluate the role of oral rehydration solutions in mice exposed nourished and malnourished or without cholera toxin (1Âg/ml). Malnourished animals showed weight loss, atrophy of the villi and reduced expression by immunofluorescence of SGTL-1. Malnutrition also caused a reduction in mRNA expression SGTL-1 and PEPT-1 and increased mRNA expression for SN-2 in mice ileum. In the model of intestinal perfusion, acute malnutrition increased intestinal secretion of electrolytes and water. CT increased the secretion of electrolytes and water into the intestinal perfusion model mice. SGli, SGln, SAla-Gln and SArg decreased secretion of electrolytes induced by CT. Just SGln failed to significantly decrease water secretion induced by CT. CT increased mRNA transcription for intestinal transporters SGTL-1, PEPT-1 and CAT-1 but not to increased transcription SN -2. Only SGli reduced water secretion induced by CT. SGli, SAla-Gln and SArg, but not SGln , decreased secretion of sodium and chloride induced by CT. The malnutrition associated with diarrhea caused by TC reduction in the transcription of mRNA for intestinal transporters SGT -1, PEPT-1, CAT-1 and SN-2. Malnutrition associated with CT increased the secretion of water when compared to the group fed exposed to TC. SGli , SAla-Gln and SArg, but not SGln, decreased water secretion induced by malnutrition associated with TC. All solutions decreased secretion of sodium and chlorid induced malnutrition associated with TC.
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Miqueo, Evangelina. „Desempenho, mortalidade e escore fecal de bezerros aleitados com diferentes dietas líquidas e terapias de reidratação quando acometidos por diarreias“. Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/11/11139/tde-07062016-183238/.

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O objetivo deste trabalho foi avaliar o efeito da utilização de sucedâneo lácteo com alto conteúdo proteico de origem vegetal no desempenho e saúde de bezerros, e avaliar métodos de reidratação para o tratamento de diarreias. No primeiro estudo foram utilizados 33 bezerros da raça Holandês distribuídos nos tratamentos: 1) Alto volume e baixa proteína (AV/BP): 8 litros, 21,4% PB; 2) Alto volume e alta proteína (AV/AP): 8 litros, 23,7% PB e 3) Baixo volume e alta proteína (BV/AP): 6 litros, 23,7% PB. Os bezerros foram alojados em abrigos individuais, com livre acesso a água e concentrado. Não houve efeito dos tratamentos para o desempenho animal (P>0,05). Os tratamentos AV/BP e AV/AP resultaram em maior consumo de sucedâneo (P<0,05), mas não afetaram o consumo de concentrado nem o consumo total (P>0,05). O escore fecal foi maior (P>0,05) para animais nos tratamentos AV/AP e BV/AP. Os animais nos tratamentos AV/BP permaneceram maior número de dias em diarreia (P<0,05), em comparação aqueles aleitados com BV/AP, os quais tiveram menos dias com vida (P<0,05). A concentração de lactato foi maior (P<0,05) para animais nos tratamentos AV/BP e AV/AP enquanto a concentração de proteína total foi maior (P<0,05) nos tratamentos AV/BP e BV/AP. Sucedâneos com elevado conteúdo de proteína de origem vegetal afetam negativamente o desempenho de bezerros podendo levar o animal a morte. No segundo estudo foram comparados três soluções de hidratação oral quanto a sua eficiência em repor eletrólitos e água, além de manter o desempenho de bezerros. Foram utilizados 42 bezerros mestiços Holandês-Jersey, distribuídos nos tratamentos: 1) Soro comum, 2) Glutellac® e 3) Soro comum + Aminogut®. Os animais foram aleitados com 4 L/d de sucedâneo lácteo até a oitava semana de vida quando foram desaleitados de forma abrupta. As terapias de reidratação foram oferecidas quando os animais apresentavam escore fecal >= 3 na escala de 1 a 5. Não houve efeito das terapias de reidratação no desempenho nem em metabólitos sanguíneos (P>0,05). O consumo voluntário de água foi maior para os animais reidratados com Glutellac®, mas o consumo total maior para os animais reidratados com Soro comum. As concentrações de HCO3 e Na+ foram maiores para os animais no tratamento Glutellac® (P=0,088 e P=0,073 respectivamente), sendo a concentração de glicose também afetada pelo protocolo de hidratação (P<0,05). A concentração de HCO3 aumentou do primeiro para o segundo dia, a de K+ e glicose diminuíram do primeiro para o segundo dia, enquanto que o Beecf teve um comportamento variável segundo a terapia de reidratação utilizada. Houve efeito da interação tratamento x dia de avaliação apenas para a concentração de BUN (P<0,05). O pH, a concentração de Na+ e Beecf foram maiores em animais mais velhos, enquanto K+, hematócrito e hemoglobina, foram menores (P<0,05). O consumo voluntário de água foi maior em animais reidratados com Glutellac®, o que junto com a simplicidade de uso, representam as principais vantagens deste método de reidratação.
The objective of this study was to evaluate the effect of milk replacer with high inclusion of vegetable protein in regard to performance and health of dairy calves, and evaluate rehydration methods for the treatment of diarrhea. In the first study 33 Holstein calvesdistributed in the treatments: 1) High volume and low protein (HV/LP): 8L/d, 21.4% CP; 2) High volume and high protein (HV/HP): 8L/d, 23.7% CP and 3) low volume and high protein (LV/HP): 6L/d, 23.7% CP. The calves were housed in individual shelters, with free access to water and starter concentrate. There was no effect of the treatments for animal performance (P>0.05). The treatments HV/LP and HV/HP resulted in higher milk replacer intake (P<0.05), but did not affect concentrate intake, neither the total dry matter intake (P>0.05). The fecal score was higher (P>0.05) for animals in treatments HV/HP and LV/HP. The animals in the treatments HV/LP remained more days in diarrhea (P<0.05), compared to LV/HP animals, which had fewer days with life (P<0.05). Lactate concentration was higher (P<0.05) for animals in treatments HV/LP and HV/HP while the concentration of total protein was higher (P<0.05) in treatments HV/LP and LV/HP. The use of milk replacer with high contents of vegetal protein, negatively affects the performance of calves and could lead to animals´ death. In the second study, three oral rehydration protocols were compared in regard to their efficiency in replace electrolytes and water, and in the maintenance of calves performance. Forty-two crossbred calves were used Holstein-Jersey, distributed in the treatments: 1) Common electrolytes oral solution, 2) Glutellac® and 3) Common electrolytes oral solution + Aminogut®. Calves were feed with 4 L/d of milk replacer until the eighth week of life when they were abruptly weaned. The rehydration therapy were offered when the animals presented fecal score >= 3 in a scale of 1 to 5. There was no effect of rehydration therapies for the variables related to animal\'s performance neither for blood metabolites (P>0.05). Voluntary water intake was greater for the animals that were rehydrated with Glutellac®, however total intake was higher for animals rehydrated with a common electrolytes oral solution. HCO3 and Na+ concentration were higher for the animals in the treatment Glutellac® (P=0.088 and p=0.073, respectively) being the glucose concentration also affected by protocol of rehydration (P<0.05). The HCO3 was increased from the first to the second day, the K+ and glucose reduced from the first to the second day, while the Beecf was variable according to rehydration therapy used. There was a significant interaction treatment x day only for the concentration of BUN (P<0.05). pH, concentration of Na+ and Beecf, were higher for older animals, while K+, hematocrit and hemoglobin, were lower (P<0.05). The voluntary water intake was significantly greater in animals rehydrated with Glutellac®, which together with simplicity of use, form the main advantages of this rehydrating.
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Koning, Lizanne. „Oral rehydration therapy in childhood diarrhoea : how educated are caregivers?“ Master's thesis, University of Cape Town, 2009. http://hdl.handle.net/11427/11849.

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Includes bibliographical references (leaves 44-58).
Thirty years ago, oral rehydration therapy (ORT) was hailed as potentially the most significant medical advance of the century. Dehydration from diarrhoea killed approximately 5 million children per year in the late 1970's. ORT is a simple and inexpensive means of treating diarrhoeal dehydration. Today 25% of the world's children have access to ORT, and it is estimated that every year it saves 500,000 lives (Drucker 1988).
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Sengwana, Manyeke Jeani. „Diarrhoea management in primary health care facilities in the Cape metropole region: the caregivers' perspective“. Thesis, University of the Western Cape, 2003. http://hdl.handle.net/11394/4594.

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Master of Public Health - MPH
This mini-thesis, assessed the use of ORT as a treatment for childhood diarrhoea in primary health care facilities in the Cape Metropole from the caregivers' perspective. Awareness and knowledge of oral rehydration therapy (ORT) and the preparation abilities of sugar salt solution (SSS) by caregivers of children younger than 5 years attending the health facilities were assessed. The availability of resources and utensils for the use of ORS packets and SSS and the accessibility to health facilities by caregivers were also determined. Using a cross sectional descriptive study design, a baseline situation review was carried out. Primary health care facilities in three heath districts namely; Khayelitsha, Nyanga and Oostenberg were purposely selected. Ninety-two caregivers in 12 facilities participated in the study. Basic analyses of quantitative data were done using Epi-Info 2002 software. Qualitative data were analysed manually. The study found that according to caregivers, all facilities used ORS packets as their immediate treatment for uncomplicated diarrhoea, and recommended sugar salt Diarrhoea Management in PHC Facilities solution as home treatment. Ninety-one percent of caregivers used ORT at home before they presented to the health facility.Of the caregivers who were advised by the health worker to use SSS at home, 60.7%, 55.8% and 60.2% in Oostenberg, Khayelitsha and Nyanga districts respectively remembered the correct ingredients and quantities to make the solution at home. Of those given ORS packets, 94.5%, 99.0% and 98.5% respectively, remembered the quantity of water to be mixed with each packet. Packets were found to be convenient and were preferred by many caregivers as compared to SSS. The advice or health education messages given to caregivers were often unclear, and there were language barriers in Brighton and Bloekombos clinics in the Oostenberg district. A litre bottle was available in 47% of caregivers' homes, 82 % had a teaspoon and all of them had access to running water. Twelve percent and 11 % admitted to not having sugar and salt respectively when they wanted to make SSS. Eighty-eight percent walked to the health facility and 12% used taxis or buses. The study concludes that ORT is widely used in primary health care facilities for diarrhoeal disease treatment, however caregiver's knowledge and preparation abilities of SSS is still limited. The resources and utensils to prepare ORT at home were fairly available in many homes, which makes SSS preparation at home feasible and acceptable.
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Gratz, Brigitte Antonia. „Anwendung von probiotischen Escherichia coli Stamm Nissle 1917 zur Therapie gastrointestinaler Dysregulationen mit der Leitsymptomatik Diarrhöe beim Hund“. Doctoral thesis, Universitätsbibliothek Leipzig, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:15-20100406-113909-3.

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Durchfallerkrankungen unterschiedlicher Genese sind eine der häufigsten Vorstellungsgründe in der Kleintierpraxis. Neben den Folgen für das betroffene Tier selbst, ist die Erkrankung oft auch eine enorme Belastung für den Besitzer. Im Rahmen der vorliegenden Arbeit wurden erste grundlegende Erkenntnisse zum Einsatz des probiotisch wirksamen Escherichia coli Stamm Nissle 1917 (EcN) als Arzneimittel bei gastrointestinalen Störungen mit der Leitsymtomatik "Diarrhöe" bei der Tierart Hund gewonnen. Aus den vorliegenden Ergebnissen lässt sich ableiten, dass EcN in der Lage ist, die Magen-Darm-Passage bei solch erkrankten Hunden lebensfähig zu überwinden. Es wurde weiter gezeigt, dass EcN einem Placebo in der Behandlung eines akuten Durchfalls bei der Tierart Hund signifikant überlegen ist.
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Meißner, Arne Matthias Kurt [Verfasser]. „Erfassung der Ätiologie, Epidemiologie und Therapie von Diarrhoen und Enterokolitiden bei hämato-onkologischen Hochrisikopatienten / Arne Matthias Kurt Meißner“. Köln : Deutsche Zentralbibliothek für Medizin, 2014. http://d-nb.info/1056004088/34.

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Leithold, Camilla [Verfasser], Karin [Akademischer Betreuer] Jordan, Patrick [Akademischer Betreuer] Michl und Ulrich [Akademischer Betreuer] Schuler. „Systematischer Review zur Prävention und Therapie der Tumortherapie-induzierten Diarrhoe / Camilla Leithold ; Karin Jordan, Patrick Michl, Ulrich Schuler“. Halle, 2016. http://d-nb.info/1116951487/34.

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Båverud, Viveca. „Clostridium difficile in horses /“. Uppsala : Dept. of Veterinary Microbiology, Swedish Univ. of Agricultural Sciences ([Institutionen för veterinärmedicinsk mikrobiologi], Sveriges lantbruksuniv.), 2002. http://epsilon.slu.se/avh/2002/91-576-6378-5.pdf.

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Bücher zum Thema "Diarrhea – therapy"

1

M, Rochwarger Arnold, Hrsg. The evaluation and treatment of the patient with diarrhea. Boston: Andover Medical Publishers, 1993.

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Jan, Holmgren, Lindberg Alf und Möllby Roland, Hrsg. Development of vaccines and drugs against diarrhea: 11th Nobel Conference, Stockholm, 1985. Lund, Sweden: Distribution, Studentlitteratur, 1986.

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Rashad, H. A reappraisal of how oral rehydration therapy affected mortality in Egypt. Washington, DC (1818 H St., N.W., Washington 20433): Population and Human Resources, Department, the World Bank, 1992.

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Kisamba-Mugerwa, C. Oral rehydration therapy in Uganda: A community-based survey on the knowledge, attitudes, and practices of oral rehydration therapy in Masindi District, Uganda : final report. [Entebbe, Uganda]: CDD Programme, Ministry of Health, 1992.

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World Health Organization (WHO). The management of diarrhoea and use of oral rehydration therapy: A joint WHO/UNICEF statement. 2. Aufl. Geneva: World Health Organization, 1985.

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Nyatoti, Violet. Knowledge, attitudes, and practices of mothers and health workers in relation to the use of sugar and salt solution in Masvingo Province. [Harare]: GTZ/MCH/HSR Mother and Child Project, Ministry of Health, 1991.

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International Symposium on Cereal Based Oral Rehydration Therapy (1989 Aga Khan University). Cereal based oral rehydration therapy for diarrhoea: Report of the International Symposium on Cereal Based Oral Rehydration Therapy, 12-14 November 1989 at the Aga Khan University, Faculy of Health Science, Karachi, Pakistan. Geneva, Switzerland: Aga Khan Foundation, 1990.

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Thillainayagam, Andrew Vivekaraj. The role of complex carbohydrate in the fluid therapy of acute diarrhoea. Manchester: University of Manchester, 1996.

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V, Rao K. Knowledge and use of oral rehydration therapy for childhood diarrhoea in India: Effects of exposure to mass media. Mumbai, India: International Institute for Population Sciences, 1998.

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Moore, Pauline. New milk-free, egg-free recipes for children: Nutritional therapy for allergenic symptoms including eczema, asthma, diarrhoea, colic, coeliac disease and ulcerative colitis. London: Foulsham, 1986.

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Buchteile zum Thema "Diarrhea – therapy"

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Benson, Al B., und Regina Stein. „Diarrhea and Constipation: Supportive Oncology Management“. In Supportive Care in Cancer Therapy, 213–25. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-291-5_12.

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DuPont, H. L., C. D. Ericsson, J. J. Mathewson und M. W. DuPont. „Quinolones for Empiric Therapy of Travelers’ Diarrhea“. In Use of Quinolones in Travel Medicine, 35–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-77077-7_5.

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Pastorek, Joseph G., und Joseph M. Miller. „Acute Bacterial Diarrhea and Bacterial Food Poisoning“. In Principles of Medical Therapy in Pregnancy, 420–23. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2415-7_48.

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Brüssow, Harald. „Control of Bacterial Diarrhea with Phages: Coverage and Safety Issues in Bacteriophage Therapy“. In Bacteriophages in the Control of Food- and Waterborne Pathogens, 273–95. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555816629.ch14.

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de Jongh, T. O. H., und A. Schierenberg. „Diarree“. In Therapie van alledaagse klachten, 227–34. Houten: Bohn Stafleu van Loghum, 2017. http://dx.doi.org/10.1007/978-90-368-1922-0_23.

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Bischoff, Stephan C. „18. Prävention und Therapie der Diarrhö mit Schwerpunkt Ernährung, Probiotika und Mikrobiota“. In Leitsymptom Diarrhö, herausgegeben von Elke Roeb und Volkhard A. J. Kempf, 251–66. Berlin, Boston: De Gruyter, 2019. http://dx.doi.org/10.1515/9783110539288-018.

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Fölsch, Ulrich R., und Ulrich Junge. „Akute Diarrhö“. In Medikamentöse Therapie in der Gastroenterologie, 77–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-87466-6_11.

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Fölsch, Ulrich R., und Ulrich Junge. „Chronische Diarrhö“. In Medikamentöse Therapie in der Gastroenterologie, 93–103. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-87466-6_12.

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Argenzio, R. A. „Species and age-dependent factors governing the clinical severity of diarrhoea“. In Comparative Veterinary Pharmacology, Toxicology and Theraphy, 345–50. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4153-3_31.

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Molla, A. M., S. A. Sarker, A. Molla, M. Khatoon und W. B. Greenough. „Rice based oral rehydration therapy in acute diarrhoea: a superior therapy and a medium for calorie supplementation“. In Child Health in the Tropics, 65–70. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5012-2_7.

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Konferenzberichte zum Thema "Diarrhea – therapy"

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Saputri, Nurul Aini Suria, Tri Nugraha Susilawati und Vitri Widyaningsih. „Relative Efficacy of Probiotics Compared with Standard Therapy for Diarrhea Treatment in Children Under Five Years of Age: A Meta-Analysis Evidence from Developing Countries“. In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.03.95.

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ABSTRACT Background: Probiotics have been widely studied in a variety of gastrointestinal diseases. There is high-quality evidence that probiotics are effective for acute infectious diarrhea. This study aimed to examine the relative efficacy of probiotics compared with standard therapy for diarrhea treatment in children under five using meta-analysis. Subjects and Method: A meta-analysis was carried out using systematic PRISMA guidelines. The review process begins with searching for articles published between 2009 and 2019 from PubMed, Clinical Key, ScienceDirect, and Scopus databases. This study obtained four articles that meet the criteria of the randomized controlled trial (RCT), the study subjects were toddlers and conducted in developing countries. A sample of 995 children was divided into two groups, 518 children received probiotics (intervention) and 477 children received standard therapy (control). The data were analyzed by Review Manager (RevMan) software 5.3 to assess Standardized Mean Difference (SMD). Results: Probiotics administration reduced duration of acute diarrhea in children under five than standard therapy, with pooled estimate= 0.30 (SMD= -0.30; 95% CI= – 0.56 to -0.03). Conclusion: Probiotics administration combined with standard therapy is effective to reduce the duration of acute diarrhea in children under five in developing countries. Keywords: acute diarrhea, probiotic, children under five Correspondence:Nurul Aini Suria Saputri. Midwifery Department, School of Health Polytechnics, Tanjungpinang/ Masters Program in Public Health, Universitas Sebelas Maret. Jl. Arief Rahman Hakim No.1, Tanjungpinang, Riau Islands. Email: ainisuriasaputri@gmail.com. Mobile: +6285743401971. DOI: https://doi.org/10.26911/the7thicph.03.95
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Nagao, T., Y. Hanawa, K. Sawada, I. Tsukimoto, I. Ikeda, M. Komazawa, K. Shiraki et al. „THE VITAMIN K DEFICIENCY IN INFANCY IN JAPAN -- THE SECOND NATIONWIDE SURVEY“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644263.

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Questionnaires were sent to 1,218 hospitals with more than 200 beds, in order to know the incidence of hemorrhagic disease due to vitamin K deficiency in infancy beyond 2 weeks after birth, during 4 and a half years, i.e. from January 1981 to June 1985. Out of the 534 cases reported, 407 had no obvious reasons for vitamin K deficiency: "idiopathic vitamin K deficiency in infancy". Other 68 cases had bleedingepisodes due to vitamin K deficiency associated with hepatobiliary lesions (e.g.congenital bile duct atresia), chronic diarrhea, long term antibiotic therapy and so on: "secondary vitamin K deficiencyin infancy". The third group consisting of 59 cases was so called "near miss" type, in which hemorrhagic tendency was discovered at the time of mass screening tests for vitamin K deficiency or by chance withoutany clinical hemorrhage. In the idiopatic group, 345 cases (84.8%) developed their bleeding episodes between 21 and 59 days of age, and 368 cases (90.4%) were wholly breast-fed. Intracranial hemorrhage was seen in 338 cases (83.0%) of this group. In most cases of this series (97.3%),no vitamin K was supplemented after birth. Administration of vitamin K is an urgent routine procedure during the first one or two months of life for all newbornbabies, although the incidence of the idiopathic vitamin K deficiency in infancyhas not decreased significantly comparedto the results of the first nation-wide survey (Jan. 1978 - Dec. 1980). This study was sponsored by the Ministry of Health and Welfare of Japan.
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Ibraheim, Hajir, Mark Samaan und Nick Powell. „PWE-024 Effectiveness of anti-inflammatory therapy in immune checkpoint inhibitor-induced diarrhoea/colitis“. In British Society of Gastroenterology, Annual General Meeting, 4–7 June 2018, Abstracts. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2018. http://dx.doi.org/10.1136/gutjnl-2018-bsgabstracts.156.

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Gupta, Vikas, Ashok Kumar Chauhan, Paramjeet Kaur, Anil Khurana, Yashpal Verma und Nupur Bansal. „Comparative evaluation of concomitant chemoradiation with weekly cisplatin and gemcitabine versus weekly cisplatin in the management of locally advanced carcinoma of uterine cervix“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685264.

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Aim: To evaluate feasibility of concomitant chemoradiation with weekly cisplatin and gemcitabine, and comparing the advantage of using this regimen over cisplatin alone in terms of disease control and toxicities in management of locally advanced carcinoma cervix. Materials and Methods: The study has been conducted on fifty previously untreated, histopathologically proven FIGO stage II B - IV A patients of carcinoma cervix, attending the Department of Radiotherapy, Post Graduate Institute of Medical Sciences, Rohtak for definitive treatment by radiation therapy. The patients were divided randomly in two groups of 25 patients each. Group I received cisplatin 40 mg/m2 and gemcitabine 125 mg/m2 with concomitant external beam radiotherapy 50 Gy/25 fractions/5 weeks, followed by intracavitary high dose rate brachytherapy 7 Gy to point A, for 3 times, once in a week. Group II received concomitant chemotherapy with cisplatin 40 mg/m2 weekly alone while radiotherapy schedule were same as in group I. Results: Total treatment duration in group I and II were 9-11 and 8-10 weeks respectively. Complete response rate in group I and II were 92% and 80%. Grade III skin and mucosal reactions was 20% in group I and none in group II. Diarrhoea was 24% in group I & 8% in group II. Grade II & III leucopenia was seen in 28% and 4% cases of group I & group II respectively. Upper gastrointestinal and renal toxicities were comparable in both arms. After six month of follow up, no evidence of disease was seen in 92% and 80% cases of group I and group II. Conclusion: If the toxicity is managed adequately in platinum based doublet group, it may produce improvement in response. Study is ongoing.
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Berichte der Organisationen zum Thema "Diarrhea – therapy"

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Cheng, Cheng, Yashuang Huang, Li Xie, Xinghui Zhu, Dongmei Chen und Cisong Cheng. Therapy of Diarrhea in COVID-19 with External Treatment of Traditional Chinese Medicine. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2020. http://dx.doi.org/10.37766/inplasy2020.11.0095.

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Sun, Shaodan, Xiaojie Lin, Yang Yang, Jingtu Ceng, Fei Luo und Xiaogang Chen. Acupoint Application Therapy for Rotavirus Diarrhea in Infants and Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, Juli 2020. http://dx.doi.org/10.37766/inplasy2020.7.0123.

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Yu, Yixuan, Chongxiang Xue, Xingyu Lu, Huijing Dong und Huijuan Cui. A Meta-analysis of clinical efficacy of traditional Chinese medicine in the treatment of chemotherapy of targeted therapy-induced diarrhea. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, Juli 2021. http://dx.doi.org/10.37766/inplasy2021.7.0039.

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