Um die anderen Arten von Veröffentlichungen zu diesem Thema anzuzeigen, folgen Sie diesem Link: CuFFT.
Dissertationen zum Thema „CuFFT“
Geben Sie eine Quelle nach APA, MLA, Chicago, Harvard und anderen Zitierweisen an
Machen Sie sich mit Top-50 Dissertationen für die Forschung zum Thema "CuFFT" bekannt.
Neben jedem Werk im Literaturverzeichnis ist die Option "Zur Bibliographie hinzufügen" verfügbar. Nutzen Sie sie, wird Ihre bibliographische Angabe des gewählten Werkes nach der nötigen Zitierweise (APA, MLA, Harvard, Chicago, Vancouver usw.) automatisch gestaltet.
Sie können auch den vollen Text der wissenschaftlichen Publikation im PDF-Format herunterladen und eine Online-Annotation der Arbeit lesen, wenn die relevanten Parameter in den Metadaten verfügbar sind.
Sehen Sie die Dissertationen für verschiedene Spezialgebieten durch und erstellen Sie Ihre Bibliographie auf korrekte Weise.
1
Stodůlka, Martin. „Akcelerace ultrazvukových simulací pomocí multi-GPU systémů“. Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2021. http://www.nusl.cz/ntk/nusl-445538.
Der volle Inhalt der QuelleAnnotation:
The main focus of this project is usage of multi - GPU systems and usage of CUDA unified memory . Its goal is to accelerate computation of 2D and 3D FFT, which is the main part of simulations in k- Wave library .K- Wave is a C++/ Matlab library used for simulations of propagation of ultrasonic waves in 1D , 2D or 3D space . Acceleration of these functions is necessary , because the simulations are computationally intensive .
2
Dean, Benjamin J. F. „The role of glutamate in rotator cuff tendinopathy : glutamate in rotator cuff tendinopathy“. Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:8f590630-b52f-4b32-a1c1-9914dbd694f3.
Der volle Inhalt der QuelleAnnotation:
Thesis questions: • Is the glutaminergic system altered in rotator cuff tendinopathy? • Is the glutaminergic system altered by common treatments? • Are glutaminergic changes related to pain symptoms? • What are the effects of glutamate and glutamate receptor modulation on tendon derived cells? Summary answers: • The glutaminergic system is altered in rotator cuff tendinopathy • Changes within this system are seen after common treatments • Specific glutaminergic changes are associated with the resolution of pain following shoulder surgery but do not predict the severity of pain symptoms • Glutamate has significant effects on tendon derived cells. What is known: It is known that extracellular glutamate concentrations are increased in both Achilles and patellar tendinopathy. It has also been previously shown that the glutamate receptors NMDAR1 and mGluR5 are upregulated in patellar tendinopathy. What this thesis adds: This thesis has shown for the first time that glutamate and NMDAR1 are increased in rotator cuff tendinopathy. Increases in cell proliferation, vascularity and HIF1α are seen after surgical rotator cuff repair and these features are not seen after glucocorticoid injection. There are significant differences between painful and pain-free rotator cuff tendons in terms of glutamate receptor expression (KA1, mGluR7 and mGluR2) and inflammatory cell numbers (CD45 and CD206). Exposure to 1.875mM glutamate for 72 hours results in reduced cell viability, decreased collagen (COL1A1 and COL3A1) and increased aggrecan gene expression; NMDAR antagonism with MK-801 attenuates the deleterious effect on cell viability but had no effect on the changes in matrix gene expression. Bias, confounding and other reasons for caution: The observational histological work was limited by the control tissue. Some control tissue was not age matched, while some of the pain-free control tendons were post-surgical intervention. Confounding factors include tendon structure, length of symptoms and previous treatments. Caution must be applied when discussing the in vivo implications of the in vitro work.
3
Wu, Bing. „Pathology of rotator cuff tendonopathy“. University of Western Australia. Centre for Orthopaedic Research, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0032.
Der volle Inhalt der QuelleAnnotation:
Tendonopathy, resulting in the loss of mechanical strength of a tendon, is a serious health problem affecting many people. The common symptom of tendonopathy is pain patients' daily activities, their participation in sport and exercise, and their ability to work are greatly compromised. Tendonopathy is considered to be a degenerative disorder caused by repetitive injury of the tendon. The most common tendon lesions are Achilles tendon rupture, lateral epicondylitis (tennis elbow) and rotator cuff tear. However, in spite of its clinical significance, our knowledge about tendonopathy is still very poor. This research was undertaken to investigate the pathology of tendonopathy. It is proposed that apoptosis, autophagic cell death and myofibroblasts play a role in the progression of tendonopathy in the rotator cuff; the aim of this study was therefore to determine if this was indeed the case. Tendon tissues were collected from 30 patients suffering from rotator cuff tears. A terminal deoxynucleotidyl transferase biotin-dUTP nick end labelling (TUNEL assay) was performed to detect apoptosis. Autophagic cell death of the tenocytes in the ruptured rotator cuff tendon was detected by immunohistochemical staining for ubiquitin. Myofibroblasts were identified immunohistochemically with anti-alpha-smooth muscle actin (anti--SMA) antibody. The distribution of apoptosis, autophagic cell death and myofibroblasts, as well as the total cell density, were assessed respectively and were correlated using a four-category (i.e. graded from 0-3) degeneration of collagen matrix. 6 The results showed that apoptosis, autophagic cell death and myofibroblasts were observed in all of the samples. The highest percentage of autophagic cell death was evidenced in the Grade 2 matrix, while the percentage of apoptosis increased significantly with the increase of matrix degeneration from Grade 0-3; a similar pattern was found for myofibroblasts. The total cell numbers varied among the matrix grades, with the maximum and minimum percentages occurring in Grades 1 and 3, respectively. It can be concluded that apoptosis, autophagic cell death and myofibroblasts might be closely related to the damage of the extracellular matrix (ECM) structure.
4
Karthikeyan, Shanmugam. „Management of rotator cuff pathology“. Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/89698/.
Der volle Inhalt der QuelleAnnotation:
The rotator cuff refers to a group of four muscles, which arise from the scapula and insert into the head of humerus forming a cuff around the shoulder joint. They contribute to shoulder movements and provide dynamic stability at the shoulder joint. Pathology of the rotator cuff is the commonest cause for shoulder pain and its severity can vary from subacromial impingement to full thickness tears. NSAIDs and corticosteroids are two of the commonest group of drugs used in treating subacromial impingement syndrome but with conflicting evidence about their relative efficacy and risk of complications. I explored the efficacy of a subacromial NSAID (Tenoxicam) injection in a double blind randomised controlled trial but found it to be less effective compared to a subacromial corticosteroid injection as measured by functional shoulder scores at six weeks. During the trial, I recognised that there were unresolved challenges in using Ultrasonography to diagnose rotator cuff pathology especially in differentiating between partial and full thickness tears. In this thesis, I have presented the normal ultrasound dimensions of the rotator cuff in asymptomatic young adults under the age of forty years, which has not been documented before. The study showed that the measurements are significantly different between men and women but not between dominant and non-dominant arms, suggesting that in every individual the contralateral shoulder can be used as a control, especially where the diagnosis is uncertain. Exploration of factors associated with the pathogenesis of rotator cuff tendinopathy showed that a critical zone of hypoperfusion in the supraspinatus tendon could be a factor but the evidence for it has been contradictory. An observational study presented in this thesis describes the microvascular blood flow in normal and a spectrum of pathological rotator cuffs (subacromial impingement, partial thickness tears and full thickness tears) using Laser Doppler Flowmetry in patients undergoing arthroscopic shoulder surgery. The study showed variations in microvascular blood flow in normal rotator cuffs but no evidence of a “critical zone”. Blood flow was found to be significantly lower in all groups of pathological rotator cuffs.
5
Gupta, Miti. „Obesity and Rotator Cuff Tendonitis“. The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1213285329.
Der volle Inhalt der Quelle
6
Benson, Richard. „The pathology of rotator cuff failure“. Thesis, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589763.
Der volle Inhalt der QuelleAnnotation:
Abstract The thesis has two aims. Firstly, to gain a greater understanding of the intrinsic mechanisms involved in rotator cuff pathology and its progression. Secondly, to investigate how outcome after operative intervention may be influenced by the macroscopic and microscopic appearance of the rotator cuff. It has been hypothesis that rotator cuff disease is part of a continuum from impingement, through partial thickness tear and leading to massive rotator cuff tears. The thesis uses this hypothesis to create a model of the stages of rotator cuff failure using the macroscopic appearance of the rotator cuff. Biopsies were taken from in vivo human rotator cuffs at different stages of the model, and investigated for evidence of a pathological failure cascade. Initially hypoxia and apoptosis were investigated as both had been previously identified as important factors in rotator cuff disease aetiology. Biopsies were analysed using immunhistochemical techniques: TUNEL (a marker for apoptosis) and BNIP-3 (a marker for hypoxia). Both demonstrated increased expression with worsening rotator cuff disease. Therefore, apoptosis appears to increase as the disease progresses and a hypoxic mechanism is implicated. A second study analysed the healing response of the rotator cuff using markers of tendon healing, VEGF( a marker of vascular remodelling) and TSG-6 (a marker of inflammation). They showed evidence of a reduced healing response in large and massive tear groups compared with controls and tendon in earlier disease. In a third clinical study, patients without full thickness tears undergoing subacromial decompression were followed up with Oxford Shoulder Score and the predictive value of the macroscopic and microscopic appearances of the bursa, coracoacromial arch and rotator cuff tendons were assessed. Biopsy samples of bursa and coracoacromial ligament were analysed using basic histological and immunohistochemical techniques. All patients showed statistically significant improvement in OSS but patients with partial tears and hooked acromion did significantly worse. The microscopic appearance did not predict outcome.
7
Matthews, Timothy. „Cellular responses in rotator cuff tears“. Thesis, Queen Mary, University of London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498371.
Der volle Inhalt der Quelle
8
Littlewood, Chris. „Self-managed exercise for rotator cuff tendinopathy“. Thesis, University of Sheffield, 2014. http://etheses.whiterose.ac.uk/6643/.
Der volle Inhalt der Quelle
9
Gillespie, William J. „A comparison of golf swing kinematics among non-injured, rotator cuff injury-repaired, and rotator cuff injury-non-repaired golfers“. Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ32115.pdf.
Der volle Inhalt der Quelle
10
Björnsson, Hallgren Hanna Cecilia. „Treatment of subacromial pain and rotator cuff tears“. Doctoral thesis, Linköpings universitet, Ortopedi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-82094.
Der volle Inhalt der QuelleAnnotation:
Shoulder pain is very common, affecting 14-21 % of the population at some time during their lifetime. The aims of this thesis were to improve the understanding of various aspects concerning the pathogenesis and treatment of subacromial pain and rotator cuff tears. Patients and healthy individuals were examined and compared in five studies: Study I) Seventy patients were retrospectively examined, clinically and with ultrasound, 15 years after arthroscopic subacromial decompression. All patients had an intact rotator cuff at surgery. Ultrasound showed significantly fewer rotator cuff tears compared to the prevalence of asymptomatic tears reported in the literature for the same age group. This indicates that arthroscopic subacromial decompression might protect the rotator cuff. Study II) Forty-two patients were retrospectively examined, clinically and with ultrasound, 39 months (mean) after an acute rotator cuff repair. All patients had pseudoparalysis after trauma, a full thickness tear and no previous history of shoulder symptoms. A delay in surgical treatment of three months and the number of tendons injured did not affect the outcome. Age affected outcome negatively. Study III) Plasma samples from 17 patients with cuff tears and 16 plasma samples from healthy age- and gender-matched controls were collected and analysed regarding the levels of matrix metalloproteinases and their inhibitors, TIMP1-4. Elevated levels of TIMP-1 were found in the patients with cuff tears compared to controls. Higher levels of TIMP-1, TIMP-3 and MMP-9 were found in patients with full-thickness tears compared to patients with partial-thickness tears. Study IV) Ninety-seven patients with longstanding subacromial pain, on the waiting-list for arthroscopic subacromial decompression, were prospectively randomised to specific shoulder exercises or control exercises for three months. Thereafter they were clinically examined and asked if they still wanted surgery. The specific shoulder exercises focusing on eccentric exercise for the rotator cuff and scapula stabilisers were found to be effective in reducing subacromial pain and improving shoulder function, thereby reducing the need for surgery. Study V) All patients including those operated, in Study IV were re-examined after one year using clinical assessment scores. The option of surgery was continuously available up to the one-year follow-up. Ultrasound and radiological examinations performed at inclusion were analysed in relation to the choice of surgery. The positive effects of the specific exercise programme were maintained after one year and significantly fewer patients in this group chose surgery. Surgery was significantly more often chosen by patients who had a low baseline shoulder score, and/or a full thickness rotator cuff tear. All patients showed significant improvement in the clinical scores one year after inclusion or one year after surgery. These results support the concept that subacromial pain has a multifactorial aetiology and that the first line of treatment should be specific shoulder exercises. When conservative treatment fails, an acceptable result can be achieved with arthroscopic subacromial decompression. The rotator cuff status is important to consider when treating and studying these patients.
11
Banerjee, Sughran. „Functional assessment of shoulder in rotator cuff disease“. Thesis, Imperial College London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538682.
Der volle Inhalt der Quelle
12
Chaudhiury, Umme Salma. „Mechanical and chemical properties of rotator cuff tendons“. Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.601169.
Der volle Inhalt der QuelleAnnotation:
Shoulder disease is the third most common musculoskeletal problem, and rotator cuff tendon tears account for the greatest proportion of shoulder complaints. Rotator cuff tears are estimated to affect between 5-30% of adults, with higher incidences of tearing and fa ilure to heal in elderly patients, placing a huge socioeconomic burden on an ageing British population. Serious concern arises as a large proportion of technically correct surgical repairs re-rupture. The intra-articular environment of the tendon often precludes nonnal healing and surgical repair is often necessary to improve pain and restore some function. It is feasible that there may be an inherent phys iological or biomechanical defect in the tissue that prevents complete heal ing without some further augmentation to the surgical repair. Improved understanding of the biochemical and biomechanical changes in tom rotator cuff tendons may help to reduce the high rerupture rates. This study aimed to characterise nonnal, and different sized rotator cuff tendon tears from small samples obtained intraoperatively to try to use tests that may potentially be clinica lly usefu l in the future. Tendon samples were mechanically tested using dynamic shear analysis, a fonn of rheology, to overcome gripping and slippage problems of very small specimens. It was found that tom tendons had a significandy reduced storage modulus compared to normal tendons, particularly for massive tears. Chemical analysis of tendons using Fourier transform infrared spectroscopy revealed that partial and different sized rotator cuff tendon tears are chemically distinguishable. The onset of rotator cuff tear pathology is mainly due to an alteration of the collagen structural arrangements, with associated changes in lipids and carbohydrates. Collagen structural changes in small and massive tendons were quantified us ing differential scanning calorimetry, which allows measurement of coHagen thermal properties as a reflection of their structural integrity. Small and massive tendon tears had reduced thermal properties and hence reduced collagen integrity when compared to normal tendons, although there was no difference between the two tear groups. Gene expression differences between the small, massive tears and normal tendons were studied using microarray analysis, and revealed that the different groups were biologically distinguishable.
13
Cornell, Hannah R. „Factors contributing to chondroplasia in degenerate rotator cuff disease“. Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:b6ee6c66-3b08-4245-8f13-d4a235f504c7.
Der volle Inhalt der QuelleAnnotation:
Chondroplasia, the development of cartilage-like characteristics in tendinous tissue, is a form of degeneration found in tendons including those of the rotator cuff. The molecular mechanism of its development is currently unknown. An examination of the features of the torn rotator cuff and the cartilage literature led to the identification of several potential drivers of chondroplasia including cell shape change/actin cytoskeleton and hypoxia. Lovastatin caused actin cytoskeleton disruption and promoted cartilage matrix deposition in the ATDC5 model. It was the most effective member of a panel of cytoskeletal inhibitors, increasing expression of the chondrocytic markers Sox5 and Sox9 and decreasing expression of COL1A1 and COL3A1 in primary human tenocytes. Its effects were dose dependent, reversible by mevalonate addition and long term treatment induced de novo expression of collagen II. Short term hypoxia upregulated VEGF-A and chondrocytic marker gene DEC1 expression but not other chondrocyte markers. Combination treatment with hypoxia did not enhance the effects of lovastatin. These data suggest that modulation of pathways that regulate the actin cytoskeleton and cell shape may alter tenocyte phenotype.
14
Jonnada, Srikanth. „Cuff-less Blood Pressure Measurement Using a Smart Phone“. Thesis, University of North Texas, 2012. https://digital.library.unt.edu/ark:/67531/metadc115102/.
Der volle Inhalt der QuelleAnnotation:
Blood pressure is vital sign information that physicians often need as preliminary data for immediate intervention during emergency situations or for regular monitoring of people with cardiovascular diseases. Despite the availability of portable blood pressure meters in the market, they are not regularly carried by people, creating a need for an ultra-portable measurement platform or device that can be easily carried and used at all times. One such device is the smartphone which, according to comScore survey is used by 26.2% of the US adult population. the mass production of these phones with built-in sensors and high computation power has created numerous possibilities for application development in different domains including biomedical. Motivated by this capability and their extensive usage, this thesis focuses on developing a blood pressure measurement platform on smartphones. Specifically, I developed a blood pressure measurement system on a smart phone using the built-in camera and a customized external microphone. the system consists of first obtaining heart beats using the microphone and finger pulse with the camera, and finally calculating the blood pressure using the recorded data. I developed techniques for finding the best location for obtaining the data, making the system usable by all categories of people. the proposed system resulted in accuracies between 90-100%, when compared to traditional blood pressure meters. the second part of this thesis presents a new system for remote heart beat monitoring using the smart phone. with the proposed system, heart beats can be transferred live by patients and monitored by physicians remotely for diagnosis. the proposed blood pressure measurement and remote monitoring systems will be able to facilitate information acquisition and decision making by the 9-1-1 operators.
15
Smith, Richard. „Investigating the role of scaffolds for rotator cuff repair“. Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:aa60e0f7-179a-41c8-8e80-7324e6780a36.
Der volle Inhalt der QuelleAnnotation:
Surgical repairs of large-massive rotator cuff tendon tears often fail. Scaffolds can be used to augment tendon repair, but few scaffolds have demonstrated clinical efficacy. The aim of this thesis was to evaluate and compare several different types of commercially available scaffolds. Three important aspects of scaffold performance were studied: mechanical properties, tenocyte response, and macrophage response. In terms of mechanical properties, synthetic scaffolds had superior macroscale mechanical properties compared to biological scaffolds, but remained significantly weaker than native human supraspinatus tendon. The microscale mechanical properties of biological scaffolds were similar to those of the human supraspinatus tendon, but synthetic scaffolds were significantly stiffer on the microscale. None of the tested scaffolds mimicked the mechanical properties of human supraspinatus tendon on both the macroscale and microscale. The tenocyte study revealed that more cells initially attached to synthetic scaffolds with aligned fibres. However, over 13 days, the human biological scaffold promoted the greatest tenocyte proliferation. The non-cross-linked porcine biological scaffold stimulated the highest expression of COL1A1 and COL3A1 mRNA. Human macrophages generated a pro-inflammatory response towards the non-cross-linked porcine biological scaffold tested. The cross-linked porcine biological scaffold prompted a chronic inflammatory response, whereas the human biological and synthetic scaffolds did not induce an overt inflammatory response. This study highlights significant variation in the properties and performance of different commercially available scaffolds. It also illustrates the inadequacy of many existing scaffolds to successfully augment a surgical rotator cuff repair. Future scaffolds should be specifically designed to meet the mechanical and biological demands of the target tissue. The pipeline of in vitro tests developed in this thesis could be used to screen new scaffolds and help determine which scaffolds to evaluate in animal models and human trials.
16
Rahal, Mouhamed. „Optimisation of nerve cuff recordings for functional electrical stimulation applications“. Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248136.
Der volle Inhalt der Quelle
17
Grewe, Jennifer R. „Outcomes of Rotator Cuff Surgery in Utah Workers’ Compensation Patients“. DigitalCommons@USU, 2011. https://digitalcommons.usu.edu/etd/1056.
Der volle Inhalt der QuelleAnnotation:
Currently, rotator cuff injuries are the most common problem for the shoulder and accounted for 4.1 million physicians visits. Partial and full thickness tears are more common in people over the age of 50. The increased prevalence of rotator cuff injuries in the United States population certainly affects the working population and often represents a significant economic burden for employers. Few studies have examined outcomes in worker compensation patients or considered biopsychosocial predictive variables for rotator cuff repairs. The current study aimed to characterize injured workers who have undergone rotator cuff repairs across a number of pre- and postprocedural variables, evaluate multidimensional functional and quality of life outcomes, and examine biopsychosocial variables predictive of success and failure in this sample.
The current study examined 93 injured workers who had undergone at least one rotator cuff repair within the past five years. Participants were solicited through the Worker’s Compensation Fund of Utah (WCF) computerized database. The current study used a retrospective cohort design, patients’ medical charts were reviewed, and various preprocedural variables were coded for analysis including age at the time of the rotator cuff repair, lawyer involvement in the claim, prior shoulder surgery history, and quantity of other compensation claims. Of the total sample, 47 patients (50.5%) were contacted and completed outcome surveys that assessed patient satisfaction, shoulder functional impairment, disability status, and general physical and mental health functioning.
Findings revealed that approximately one third of the patients were totally disabled (29.8%), had poor shoulder specific functioning (36.2%), and were dissatisfied with their current shoulder condition (31.7%). A multivariate regression model was utilized in predicting patient outcomes. Specifically, the number of WCF claims of the patient was a robust predictor of multidimensional outcomes, while age and gender were less predictive of outcomes, and the presence of a prior shoulder surgery reflected no predictive power. Results of descriptive, correlational, and regression analyses are compared to existing data for rotator cuff repair patients when available or to other surgical procedures with similar populations. The study limitations are discussed, such as small sample size, the retrospective design, and lack of matched controls.
18
Chin, LiKang. „Tyramine Substituted-Hyaluronan Enriched Fascia for Rotator Cuff Tendon Repair“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1291410773.
Der volle Inhalt der Quelle
19
Murphy, Richard James. „Development of tissue and imaging biomarkers of rotator cuff tendinopathy“. Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:b63377cb-b569-41dc-a3a8-099743dd66d3.
Der volle Inhalt der QuelleAnnotation:
Rotator cuff tendinopathy accounts for the majority of cases of shoulder pain, however, the aetiology and pathophysiology of the condition is poorly understood and treatment interventions for the condition have been introduced on an empirical basis, guided only by unproven theories of biological and structural changes in and around the affected tissue. This thesis explores changes in the provision of surgical interventions for rotator cuff tendinopathy, showing a rapid, sustained increase over the last decade. Investigation into the use of ultrasound as a clinical and research tool led to the development of an independent learning method for surgeons using the modality for shoulder imaging and highlighted the technological limitations of contrast enhanced ultrasound in assessing the microvascularity of the supraspinatus tendon. Development of a novel biopsy method for sampling the supraspinatus tendon permitted collection of tissue samples from several cohorts of individuals with rotator cuff tendinopathy. These studies, for the first time, described tissue changes across the whole spectrum of pathology suggesting the possibility of an early inflammatory phase of the condition followed by tissue senescence and reduced viability as pathology progressed. Paired samples taken before and after treatment identified reduced tissue activity in response to glucocorticoid therapy and a potential healing response from the supraspinatus tendon following surgical repair. Significant deterioration in tissue activity and viability was shown as age increased in a large cohort of individuals, highlighting the major impact of ageing as a factor in the onset and progression of rotator cuff tendinopathy. The techniques introduced provide standardised, reproducible methods for further evaluation of rotator cuff tendinopathy and the development of novel therapeutic interventions.
20
Egroo, Marine Charlotte Emeline Van. „Fisioterapia após artroscopia por rotura da coifa dos rotadores: abordagem mais eficaz - uma revisão bibliográfica“. Bachelor's thesis, [s.n.], 2017. http://hdl.handle.net/10284/5889.
Der volle Inhalt der QuelleAnnotation:
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em FisioterapiaObjetivo: Perceber qual o tipo de abordagem mais eficaz em Fisioterapia e que permite que o sujeito regresse o mais precocemente possível à sua vida diária otimizando a mesma. Metodologia: Pesquisa computorizada nas bases de dados Pubmed/Medline, B-On, ScienceDirect e PEDro para identificar estudos randomizados controlados que avaliassem os protocolos de Fisioterapia após duma artroscopia da rotura da coifa dos rotadores. Resultados: Nesta revisão foram incluídos 5 artigos envolvendo 356 indivíduos, com classificação metodológica de 7,6 na escala de PEDro. Dos artigos mencionados nesta revisão, 3 fazem a comparação de um protocolo de reabilitação rápido e um protocolo lento, 1 engloba um protocolo com campo eletromagnético pulsátil e protocolo manual, e 1 associa exercícios com roldanas aos exercícios de mobilização manual com diferentes particularidades entre os dois grupos. Conclusão: Não nos foi possível perceber qual abordagem em Fisioterapia mais eficaz pela elevada variabilidade de protocolos encontrados.
Objective: To understand the most efficient type of approach in physiotherapy that allows the subject to return as early as possible to their daily life, optimizing it. Methodology: Computerized search in the databases Pubmed / Medline, B-On, ScienceDirect and PEDro to identify randomized controlled trials that evaluaté d the physiotherapy protocols after an arthroscopy of rotator cuff rupture. Results: In this review 5 articles were included involving 356 individuals, with a methodological classification of 7.6 on the PEDro scale. Of the articles mentioned in this review, 3 refer to the comparison of a rapid rehabilitation protocol and a lens protocol, 1 encompasses a protocol with pulsating electromagnetic field and manual protocol, and 1 associaté s exercises with pulleys to manual mobilization exercises with different peculiarity between the Two groups. Conclusion: It was not possible to perceive which approach in physiotherapy is more effective because of the high variability of protocols found.
N/A
21
Meyer, Dominik. „Changes in the muscles of the rotator cuff following tendon tear /“. Zürich, 2005. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000254621.
Der volle Inhalt der Quelle
22
Hawkes, David. „Factors Affecting Shoulder Function in Patients with Massive Rotator Cuff Tears“. Thesis, University of Liverpool, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526945.
Der volle Inhalt der Quelle
23
Dürr, Julian [Verfasser]. „Mittelfristige Ergebnisse der inversen Schulterprothese bei ''Cuff-Tear'' Arthropathie / Julian Dürr“. Ulm : Universität Ulm, 2019. http://d-nb.info/1194465919/34.
Der volle Inhalt der Quelle
24
Raghava, Parthasarathy. „Biomechanical evaluation of proximal humerus fracture fixation and rotator cuff repair“. Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2008m/raghava.pdf.
Der volle Inhalt der Quelle
25
Gill, Harmeet (Harmeet Kaur). „The behavior of rotator cuff tendon cells in three-dimensional culture“. Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/40423.
Der volle Inhalt der QuelleAnnotation:
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.Includes bibliographical references (leaves 37-41).
The rotator cuff is composed of the supraspinatus, infraspinatus, subcapularis, and teres minor tendons. Rotator cuff injuries are common athletic and occupational injuries that surgery cannot fully repair. Therefore tendon tissue engineering can provide alternatives to surgical solutions. Tendons are composed of parallel lines of bundles of collagen fibers and fibroblasts called fascicles and a glycoprotein, superficial zone protein (SZP), which is expressed by the gene, proteoglycan 4 (PRG4) may play a role in joint and intrafascicular lubrication. Studies have shown that a smooth muscle actin isoform (SMA), which plays a role in the contraction of smooth muscle cells, is expressed in the rotator cuff tendon cells. Previous investigations have been conducted to study PRG4 expression and distribution in different regions of the infraspinatus (ISP) tendon. The aim of this study was to investigate the behavior of adult goat ISP tendon cells and bovine bone marrow-derived mesenchymal stem cells (BMSCs) cultured in three-dimensional pellets in chondrogenic (CM), expansion (EM), and tenogenic media(TM).
(cont.) The focus was on the effects of such growth factors as TGF-[beta]1 and hormones such as dexamethasone and various culture methods, such as the use of 96-well plates and 15 ml tubes, on the ISP tendon cells' and BMSCs' cell proliferation, chondrogenesis, and expression of PRG4 and SMA. ISP tendon cells and BMSCs were obtained from five adult Spanish goats ranging. After 14 days, the pellet cultures were analyzed using Safranin-O staining and immunohistochemical staining for SZP and SMA. The biochemical contents of the cell pellet cultures were also evaluated using a DNA assay on days 0 and 14 and a GAG assay on day 14. It was found that CM, containing TGF-[beta]1 and dexamethasone, induced the most cell proliferation and chondrogenesis. SZP was expressed in all of the ISP tendon cells pellet cultures that were cultured in tubes. In comparison to the larger CM-pellets, the ISP tendon and BMSC EM- and TM- pellets cultured in tubes had higher percentages of SMA present. However SMA was also expressed in the CM-pellets cultured in the 96-well plates.
(cont.) The results of our study showed that environmental differences can change SMA expression. Further investigations on tendon cells and the effects of growth factors, bone morphogenetic proteins (BMPs), and culture methods on the cell proliferation, chondrogenesis, and SZP and SMA expression need to be conducted.
by Harmeet Gill.
S.B.
26
Goehring, Meri T. „Retrospective study of the correlates of post rotator-cuff surgical outcomes“. Diss., NSUWorks, 2006. https://nsuworks.nova.edu/hpd_pt_stuetd/42.
Der volle Inhalt der Quelle
27
McDonald, Rachel Anne. „A Combination Optical and Electrical Nerve Cuff for Rat Peripheral Nerve“. Master's thesis, Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/599756.
Der volle Inhalt der QuelleAnnotation:
BioengineeringM.S.
Spinal cord injury results in life-long damage to sensory and motor functions. Recovery from these injuries is limited and often insufficient because the lack of stimulation from supraspinal systems results in further atrophy of the damaged neural pathways. Current studies have shown that repeated sensory activity obtained by applying stimulation enhances plasticity of neural circuits, and in turn increases the ability to create new pathways able to compensate for the damaged neurons. Functional electrical stimulation has been proven to show success in this form of rehabilitation, but it has its limitations. Stimulating neural pathways with electricity results in also stimulating surrounding neurons and muscle tissue. This results in attenuation of the intended effect. The use of optogenetics mitigates this issue, but comes with its own complications. Optogenetics is a growing method of neural stimulation which utilizes genetic modification to create light activated ion channels in neurons to allow for activation or suppression of neural pathways. In order to activate the neurons, light of the appropriate wavelength must be able to penetrate the nerves. Applying the light transcutaneously is insufficient, as the skin and muscle tissue attenuate the signal. The target nerve may also move relative to an external point on the body, creating further inconsistency. Specifically in the case of using a rat model, an external object will be immediately removed by the animal. This thesis seeks to address this issue for a rat model by designing a nerve cuff capable of both optical and electrical stimulation. This device will be scaled to fit the sciatic nerve of a rat and allow for both optical activation and inhibition of the neural activity. It will be wired such that each stimulus may be operated individually or in conjunction with each other. The simultaneous stimulation is required in order to validate the neural inhibition facet. The circuit itself will be validated through the use of an optical stimulation rig, using a photoreceptor in place of an EMG. The application of the cuff will be verified in a live naive rat. Aim 1: Design and build an implantable electrical stimulation nerve cuff for the sciatic nerve of rats. An electrical nerve cuff for the sciatic nerve of a rat will be designed and assembled such that it is able to reliably activate the H-reflex. For it to be used in a walking rat, the cuff must be compatible with a head mount in order to prevent the rat from being able to chew at the wiring or their exit point. The cuff will be controlled through a Matlab program that is able to output specified signals and compare these outputs directly with the resultant EMG inputs. Aim 2: Implement LEDs onto the cuff and perform validation experiments. Light delivery capability will be added to the cuff through the use of LEDs. The functionality of the cuff will be validated through tests on naive rats. If successful, only an electric stimulation will result in a muscle twitch. An optical stimulation should result in no twitches, which would then validate that no current is leaking from the nerve cuff, given that the rat does not express any light sensitive protein channels. Ultimately, with a rat expressing ChR2 opsins on the sciatic nerve, an activation of the nerve using a blue light of wavelength 470nm will result in activating an h-wave without an m-wave when optically stimulated. Similarly, using the nerve cuff with a rat expressing ArchT opsins will result in suppressing the h-wave from an electric stimulation once the sciatic nerve is illuminated with green light of a wavelength of 520 nm.
Temple University--Theses
28
Polasek, Katharine Hopkins. „CLINICAL IMPLEMENTATION OF NERVE CUFF ELECTRODES FOR AN UPPER EXTREMITY NEUROPROSTHESIS“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1181323620.
Der volle Inhalt der Quelle
29
Brill, Natalie Amber. „Optimization of High Density Nerve Cuff Stimulation in Upper Extremity Nerves“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1418147191.
Der volle Inhalt der Quelle
30
Walline, Erin Kurusz. „The development of an index for the proximal upper extremity“. Texas A&M University, 2003. http://hdl.handle.net/1969.1/3868.
Der volle Inhalt der QuelleAnnotation:
Analysis techniques specific to the proximal upper extremity have historically
been overlooked in the field of ergonomics. This research effort provides a methodology
that will allow the ergonomics practitioner to analyze a job and predict whether or not
that job exposes workers to increased risk of proximal upper extremity disorders.
Literature from the fields of physiology, biomechanics, and epidemiology was
assimilated in order to understand the theories of pathogenesis of disorders in the rotator
cuff and to identify the risk factors associated with proximal upper extremity disorders. A
retrospective epidemiological study was conducted to identify job task variables that may
contribute to the occurrence of proximal upper extremity disorders. Two proximal upper
extremity constructs were proposed: a fatigue-based model and a compressive load-based
model. The constructs incorporated lessons learned from the literature and results from
the epidemiological study. Validation of the models was performed using data from the
epidemiological study. It was determined that the fatigue-based model was a good
predictor of proximal upper extremity disorders.
31
Sanner, Brian. „METHOD OF FABRICATION FOR NERVE CUFF ELECTRODES FOR USE IN ANIMAL MODELS“. Thesis, Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/53738.
Der volle Inhalt der QuelleAnnotation:
Many electrophysiological experiments require the recording, stimulating, or both in the peripheral nervous system. There are many electrodes currently on the market, but they are either not designed for implantation or are not robust enough to be used multiple times in situ. The cost of buying these electrodes from a manufacturer can be prohibitive and many labs prefer to make their own. This introduces variability between studies, as different techniques and configurations in the design and fabrication of electrodes can create variance in electrical impedance, spatial arrangement, or other factors. This paper presents a detailed methodology for the construction of electrodes that are robust, have uniform impedance values of Z = 2.38 ± 0.906 kΩ. at 1 kHz alternating current (AC), and can be used in multiple in vitro or in situ experiments, or for chronic implantation in vivo. This method will reduce the amount of time and material needed to construct electrodes for experimental studies in animals.
32
Thompson-Fawcett, Mark W. „Columnar cuff, anal transitional zone and ileal pouch mucosa in restorative proctocolectomy“. Thesis, University of Auckland, 2003. http://hdl.handle.net/2292/5495.
Der volle Inhalt der QuelleAnnotation:
The formation of a pelvic ileal reservoir or pouch for patients requiring a proctocolectomy for ulcerative colitis or familial adenomatous polyposis (FAP) has gained rapid favour over recent years. The operation has evolved by empiric practice with the progressive refinement of operative technique. There is still debate over whether to retain or remove the anal transitional zone (ATZ). This debate relates to concern about the neoplastic and inflammatory potential of diseased mucosa if retained in the anal canal. Similarly the chronic inflammatory changes observed in ileal pouch mucosa have raised the possibility that neoplasia may be a long term consequence of forming the ileum into a pouch. This thesis investigates these issues. The work begins with a review of the literature on the ATZ and its importance in restorative proctocolectomy. Following this a detailed study of the micro anatomy of the anal canal is carried out on 28 anal canals. The median span of the ATZ was found to be only 4.5 millimetres and it contains almost no columnar epithelium. However an important area termed the columnar cuff was identified. In a patient who does not have a mucosectomy, the columnar cuff constitutes a span of diseased Columnar epithelium extending over 1 5 to 2.5 cm in the upper anal canal. Long term concerns need to focus on the columnar cuff rather than the ATZ. The columnar cuff and ATZ in 113 patients with an ileal pouch has been studied. These patients had an examination with the intention of biopsying the anal canal and ileal pouch to study the ATZ and columnar cuff. It was possible to obtain a successful biopsy of the columnar cuff in 72% of cases. The technique of staining for the small bowel brush border enzyme sucrase isomaltase has been developed and shown to reliably distinguish between pouch mucosa with villous atrophy and columnar cuff mucosa. The same group of patients was followed over a 2.5 year period and 9% were shown to have symptomatic ‘cuffitis’. A histological scoring system is described and a diagnostic triad of symptoms, endoscopic inflammation and acute inflammation on histology is put forward as a way to diagnose cuffitis. The same 113 patients had columnar cuff biopsies examined for dysplasia and aneuploidy at a mean of 2.5 years after pouch formation and 10.1 years after the diagnosis of ulcerative colitis. No dysplasia was found but one patient had aneuploidy in the columnar cuff. The final part of the work focuses on investigating the risk of neoplasia in ileal pouches. This work draws on a large cohort of 1221 patients with an ileal pouch and selects out a potentially higher risk group for pouch neoplasia. 106 patients who had a pouch for ulcerative colitis were selected, including 34 with chronic pouchitis. In addition 33 patients who had a pouch for FAP were studied. In the ulcerative colitis group one patient was found to have low grade dysplasia and aneuploidy and a further two patients aneuploidy. The risk of neoplasia in an ileal pouch for ulcerative colitis appears low and chronic pouchitis was not identified as a particular risk factor. In contrast adenomatous polyps were found in the ileal pouch of 42% of patients with FAP. It appears that forming the terminal ileum into a reservoir promotes the formation of ileal polyps. In conclusion forming the ileum into a pelvic reservoir to maintain continence appears to be a safe procedure with medium term follow up. It will be important to continue to gather data to establish the natural history of an ileal pouch. In the interim a level of follow up and surveillance for some groups of patients may be wise.Whole document restricted, but available by request, use the feedback form to request access.
33
Pryor, David Keith. „The development of a rotator cuff evaluation tool for the throwing athlete“. Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5728.
Der volle Inhalt der Quelle
34
Carpenter, Trevor Keith. „Importance of local haemodynamics in the performance of the Miller cuff anastomosis“. Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.263907.
Der volle Inhalt der Quelle
35
Dweiri, yazan M. „Extracting Voluntary Activity of Fascicular Sources within Peripheral Nerves with Cuff Electrodes“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1449247553.
Der volle Inhalt der Quelle
36
Seitz, Amee. „Mechanisms of Rotator Cuff Disease: Alterations of Scapular Kinematics on Subacromial Space“. VCU Scholars Compass, 2010. http://scholarscompass.vcu.edu/etd/2271.
Der volle Inhalt der QuelleAnnotation:
Rotator cuff disease is multi-factored and has been attributed to both intrinsic and extrinsic factors. Extrinsic factors contribute to compression of the rotator cuff tendons. Intrinsic factors that contribute to rotator cuff tendon degradation with tensile/shear overload include alterations in biology, mechanical properties, morphology, and vascularity. Subacromial impingement is related to factors that encroach upon the subacromial space, while internal impingement affects the articular side of the tendons adjacent to glenoid. While the mechanisms of impingement are varied, further research is necessary to improve treatment and patient outcomes. Chapter 2 is a thorough review of literature on the mechanisms of rotator cuff disease. Alterations in scapular kinematics may influence subacromial space and either contribute to the etiology of subacromial impingement with rotator cuff tendon compression or serve as a compensation to alleviate compression. Furthermore alterations in scapular position may directly influence rotator cuff muscle strength. Chapter 3 compares the influence of the scapular assistance test on scapular upward rotation, posterior tilt, subacromial space, and shoulder strength between healthy individuals and subjects with subacromial impingement syndrome. Scapular upward rotation and posterior tilt induced with scapular assistance test appears to influence subacromial space, but not shoulder muscle strength; however, the influence of these scapular rotations do not differ between asymptomatic individuals and those with subacromial impingement. Furthermore scapular posterior tilt appears to have a greater influence on increasing subacromial space and should be emphasized in the treatment of individuals with subacromial impingement. In chapter 4, we examine the influence that obvious scapular dyskinesis and passive scapular correction with the scapular assistance test have on 3D scapular kinematics and subacromial space. Scapular dyskinesis did not alter scapular kinematics or acromiohumeral distance during active elevation in static positions, in the scapular plane, and without a load when compared to those without scapular dyskinesis. This suggests other contributing factors, such as pain, increased load, or fatigue is requisite to alterations in scapular kinematics or AHD. Passive correction with the scapular assistance test increased scapular upward rotation, posterior tilt, and subacromial space in individuals with and without dyskinesis. In patients with obvious dyskinesis, there was a greater increase in scapular upward rotation with passive scapular assistance. This increased scapular upward rotation had a negative relationship with change in the acromiohumeral distance. The scapular dyskinesis test increased acromiohumeral distance and therefore may be helpful identifying individuals where subacromial compression is producing symptoms, regardless of dyskinesis. The results of this research suggest scapular kinematics and subacromial space are altered with the passive maneuver of the scapular assistance test in all individuals, regardless of subacromial impingement syndrome or scapular dyskinesis. Scapular dyskinesis alone may not be detrimental to scapular position and subacromial space when evaluated in static positions of active arm elevation. Other potential factors may be required to alter scapular kinematics to reduce subacromial space including pain, dynamic movement, load or fatigue. Further study is necessary to determine the influence of the combination of these factors in individuals with scapular dyskinesis.
37
Young, Peter Jeffrey. „Pulmonary aspiration in mechanical ventilation“. Thesis, University of East Anglia, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323263.
Der volle Inhalt der QuelleAnnotation:
Pulmonary aspiration in mechanical ventilation occurs despite appropriate inflation of the tracheal tube cuff. After anaesthesiath is can causep ostoperative and, in critically ill patients, ventilator-associated pneumonia. Cuff over-inflation exerts excessive pressure on the tracheal mucosa causing injury. High volume low pressure (HVLP) cuffs permit wall pressure control as the intracuff pressure (CP) is the tracheal wall pressure (TWP). Unfortunately, at the cuff wall, folds and channels and, therefore, fluid leakage occur. Low volume high pressure (LVHP) cuffs develop neither folds nor associated leakage, but TWP is not easily inferred from CP and excessive pressures can result in tracheal injury. This thesis examines the problem of aspiration in a model, in anaesthetised patients and in the critically ill. In the model, protection against leakage resulted from positive end-expiratory pressure and cuff lubrication. Two tracheal cuff prototypes are introduced. Firstly, the compliant HVLP cuff is one with a tapered shape made of highly compliant material. Within the model this produced a circumferential band at the cuff wall without folds thus effectively eliminating channels and leakage. Secondly, the prototype pressure limited cuff (PLC) is a latex LVHP cuff with inflation characteristics such that TWP can be inferred from CP and maintained at an acceptable level. Within the model the PLC prevented leakage at acceptable TWPs. For clinical use a constant pressure inflation device is required to provide uninterrupted protection, although notably HVLP cuffs allow leakage despite this. The PLC prevented dye aspiration in 100% of tracheally intubated critically ill patients compared with 13% of the control HVLP group (p<0.01). A silicone cuff with similar inflation characteristics, yet improved biocompatability and shelf life, prevented dye aspiration in 100% of patients with tracheostomies compared to 0% of the HVLP control group (p=0.001). HVLP cuff lubrication delayed dye aspiration for 1 to 5 days (p<0.05).
38
Alraddadi, Abdulrahman. „Anatomical variations and degenerative features of the coracoacromial ligament (CAL) in shoulders with rotator cuff tears“. Thesis, University of Dundee, 2016. https://discovery.dundee.ac.uk/en/studentTheses/1e7fa407-06e8-4aab-83fb-0019d9f05099.
Der volle Inhalt der QuelleAnnotation:
The purpose of this study is to evaluate anatomical variations of the coracoacromial ligament (CAL) in relation to the etiology of subacromial impingement syndrome and rotator cuff tears. A knowledge and understanding of these variations will help to determine how such variations may influence the surrounding tissues and how the biomechanics of the shoulder works, as well as improving accurate diagnosis and subsequent treatment of shoulder impingement syndrome. The methodological approach involved the dissection of 220 cadaveric shoulders in the Centre for Anatomy and Human Identification (CAHID) with a mean age of 82 years (range 53 to 102 years). The CAL was classified according to its morphology and composed band number. The rotator cuff tendons were inspected for tears that were categorized into partial bursal and complete tears. Furthermore, the study inspected the CAL’s parameters and attachment sites: degenerative changes include acromial and coracoid spurs and attrition lesions at the undersurface of the acromion. Results: the multiple banded ligament was the most commonly observed type and was seen in 101 (46%) specimens. The attachment sites of the ligament varied as the size or number of bands of the ligament increased. An association was found between rotator cuff tears and shoulders which had three or more CAL bands (52%). In addition, shoulders with rotator cuff tears had wider attachments, thicker ligaments and larger subacromial insertions. Shoulders with rotator cuff tears also had a significant incidence and size of acromial spurs. The size of the spurs was correlated with the size of the CAL and attrition lesions on the undersurface of the acromion, and changes in morphology of the acromion. Attrition lesions at the subacromial insertion of the CAL were associated with tears in the rotator cuff tendons, and worsened as the size of the subacromial insertion increased. In conclusion, anatomical variations of the CAL showed a relationship with rotator cuff tears.
39
Ruck, Meredith L. „A Comparison of Cryopress and Cryo-Cuff Effects on Ankle Edema and Pain“. Ohio University / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1126214268.
Der volle Inhalt der Quelle
40
Childers, Erin P. „Tunable Poly(ester urea)s for Tissue Engineering Applications“. University of Akron / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=akron1478691327581315.
Der volle Inhalt der Quelle
41
Mayor, Elizabeth Laura. „Fabrication and Characterization of Electrospun Poly-Caprolactone-Gelatin Composite Cuffs for Tissue Engineered Blood Vessels“. Digital WPI, 2015. https://digitalcommons.wpi.edu/etd-theses/512.
Der volle Inhalt der QuelleAnnotation:
Strong, durable terminal regions that can be easily handled by researchers and surgeons are a key factor in the successful fabrication of tissue engineered blood vessels (TEBV). The goal of this study was to fabricate and characterize electrospun cuffs made of poly-caprolactone (PCL) combined with gelatin that reinforce and strengthen each end of cell-derived vascular tissue tubes. PCL is ideal for vascular tissue engineering applications due to its mechanical properties; however, PCL alone does not support cell attachment. Therefore, we introduced gelatin, a natural matrix-derived protein, into the electrospun material to promote cell adhesion. This work compared the effects of two different methods for introducing gelatin into the PCL materials: gelatin coating and gelatin co-electrospinning. Porosity, pore size, fiber diameter, and mechanical properties of the electrospun materials were measured in order to compare the features of gelatin PCL composites that have the greatest impact on cellular infiltration. Porosity was quantified by liquid intrusion, fiber diameter and pore size were measured using scanning electron microscopy, and tensile mechanical testing was used to evaluate strength, elastic modulus, and extensibility. Attachment and outgrowth of smooth muscle cells onto cuff materials was measured to evaluate differences in cellular interactions between materials by using a metabolic attachment assay and a cellular outgrowth assay. Finally, cuffs were fused with totally cell-derived TEBV and the integration of cuffs with tissue was evaluated by longitudinal pull to failure testing and histological analysis. Overall, these cuffs were shown to be able to add length and increase strength to the ends of TEBV for tube cannulation and manipulation during in vitro culture. In particular, PCL:gelatin cospun cuffs were shown to improve cellular attachment and cuff fusion compared to pure PCL cuffs, while still increasing the strength of the TEBV terminal ends.
42
Ruck, Meredith L. „A comparision of cryopress and cryo/cuff effects on ankle edema and pain“. Ohio : Ohio University, 2005. http://www.ohiolink.edu/etd/view.cgi?ohiou1126214268.
Der volle Inhalt der Quelle
43
Baring, Toby. „Integrity of the repaired rotator cuff; a roentgen stereophotogrammetric analysis with ultrasound comparison“. Thesis, Imperial College London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529381.
Der volle Inhalt der Quelle
44
Crossley, Kent Westerberg. „Effect of Cuff Pressure on Blood Flow DuringBlood Flow-Restricted Rest and Exercise“. BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8259.
Der volle Inhalt der QuelleAnnotation:
Purpose: The purpose of this study was to investigate the blood flow/pressure relationship (linear or nonlinear) in the superficial femoral artery when seated, as well as to investigate blood flow changes with exercise using varying cuff pressures and a preexercise (PE) condition. The presence of venous outflow with occlusion at rest and exercise was also investigated.Methods: Twenty-three subjects visited the lab on 3 occasions. First to determine linearity of blood flow using 0% to 90% arterial occlusion pressure (AOP), and venous outflow at rest and during exercise with cuff inflated to 40% AOP. Subsequent visits compared blood flow between rest and PE conditions to determine average blood flow, heart rate, systolic and diastolic blood pressure changes in response to a blood flow-restricted (BFR) exercise protocol. Results: Blood flow/pressure relationship is nonlinear at the superficial femoral artery (p < 0.01). No significant differences in average blood flow, conductance or mean arterial pressure (MAP) were found between 30% to 80% AOP (p = 1.0 to .08). Blood flow is not significantly different between rest and PE groups (p = 0.49) although initial 40% AOP and 40% exercise arterial occlusion pressure (EAOP) values were different between rest and PE groups. (p < 0.01). Conclusion: The nonlinear relationship at the superficial femoral artery demonstrates higher cuff pressures are not necessary to reduce blood flow in BFR exercise of the lower extremity. Furthermore, PE or warm-up is not necessary prior to determining EAOP as it does not alter blood flow responses during BFR exercise. We found evidence of venous outflow above the cuff both at rest and during exercise at 40% AOP.
45
Park, Hyun-Joo. „Motion control of neuromuscular skeletal systems using a multiple contact nerve cuff electrode“. Case Western Reserve University School of Graduate Studies / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=case1309506374.
Der volle Inhalt der Quelle
46
Aurora, Amit. „DESIGN, DEVELOPMENT AND BIOMECHANICAL ANALYSIS OF SCAFFOLDS FOR AUGMENTATION OF ROTATOR CUFF REPAIRS“. Cleveland State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=csu1293910881.
Der volle Inhalt der Quelle
47
Blake, C. H. „Exploring the non-invasive diagnosis of bladder outlet obstruction using a penile cuff“. Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1445291/.
Der volle Inhalt der QuelleAnnotation:
Introduction: It has been proposed that all men should undergo invasive pressure flow studies (PFS) prior to bladder outlet surgery. However, expense and morbidity limit the use of this investigation. A non-invasive technique for measuring bladder contractility using controlled inflation of a penile cuff has been developed. In work in an experimental model there is also evidence to suggest that this technique may be used to measure urethral opening pressure. The purpose of this thesis is to validate the penile cuff technique and to confirm whether this may used to diagnose bladder outlet obstruction (BOO) and obviate the need for invasive PFS prior to bladder outlet surgery. We also aim to elucidate whether cuff measurements can provide a non-invasive estimation of urethral opening pressure. Methods: 118 patients were investigated with free flow rates, invasive pressure flow studies, free cuff test, simultaneous cuff test and invasive PFS, and voiding urethral pressure profile (VUPP) measurements. Cuff pressure at flow interruption "pcuff.int" was compared with isovolumetric bladder pressure as a measure of bladder contractility. This was then used in conjunction with urinary flow rate to test a proposed non-invasive nomogram for diagnosis of bladder outlet obstruction. Cuff pressure at which flow rate starts to fall "pcuffknee", proposed as a measure of urethral opening pressure, was compared with estimations of urethral opening pressure taken from invasive pressure flow studies and VUPP's. Results: pcuff.int provides a valid estimation of isovolumetric bladder pressure. When used in combination with flow rate measurements this can be used to diagnose or exclude BOO in approximately two thirds of men, using a modification of the ICS nomogram. Although pcuff.knee does not correspond precisely with the previously described measures of urethral opening pressure, there is reasonable evidence to support our hypothesis that Pcuff knee may provide a simple and non-invasive estimation of urethral opening pressure.
48
Guiot, Nicolas. „A influência da largura e pressão do manguito na força muscular e hipertrofia com treinamento de restrição do fluxo sanguíneo“. Bachelor's thesis, [s.n.], 2020. http://hdl.handle.net/10284/9124.
Der volle Inhalt der QuelleAnnotation:
Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciado em FisioterapiaContexto: O treinamento de restrição do fluxo sanguíneo (BFR) é uma alternativa de baixa intensidade ao exercício resistido de carga pesada. Ele envolve a aplicação de um manguito em torno de um membro para restringir o fluxo sanguíneo. No entanto, a influência dos parâmetros do manguito na força muscular e hipertrofia não é clara. Objetivo: Analisar o efeito da largura e pressão do manguito na força muscular e na hipertrofia em diferentes populações, com base na experiência de treinamento, na idade e nos membros onde o BFR esta aplicado. Métodos: Foram incluídos ensaios randomizados controlados sobre o treinamento de BFR, com avaliação de força e hipertrofia pré e pós-treinamento, discutindo de parâmetros do manguito, publicados em português, francês, espanhol, inglês e russo, com pelo menos 4 pontos na escala de PEDro. Resultados: Foram detetadas diferenças importantes entre as populações, com base na experiência de treinamento, na idade e nos membros onde o BFR esta aplicado. Conclusão: Com base nos dados atuais, a força muscular máxima e a hipertrofia podem ser otimizadas por parâmetros específicos do manguito, de acordo com a experiência do treinamento, a idade e a aplicação do membro.
Background: Blood flow restriction (BFR) training is a low intensity alternative to heavy-load resistance exercise. It involves the application of a cuff around a limb to restrict blood flow. However, the influence of cuff parameters on muscle strength and hypertrophy is unclear. Objective: To analyse the effect of cuff width and pressure on muscle strength and size adaptions in different populations based on training experience, age and limb application. Methods: Randomized control trials about BFR training, with pre and post-training strength and hypertrophy assessment, discussing cuff parameters, in Portuguese, French, Spanish, English and Russian with significant results (P 0,05), with at least 4 points on the PEDro scale were included in this review. Results: Important differences were detected between classes based on training experience, age and limb application. Conclusion: Based on the present data, maximum muscle strength and size adaptation may be optimized by specific cuff parameters according to training experience, age and limb application.
N/A
49
Crouch, David Alexander. „Morphometric analysis of neural tissue following long-term implantation of nerve cuffs in the cat forelimb“. Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/mq24113.pdf.
Der volle Inhalt der Quelle
50
Orsini, Valentina. „Shoulder kinematic evaluation in patients with rotator cuff tears using inertial and magnetic sensors“. Master's thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amslaurea.unibo.it/19455/.
Der volle Inhalt der QuelleAnnotation:
Questo progetto di tesi fa parte di un più ampio studio clinico condotto all’interno dell’azienda NCS Lab (Carpi,(MO)), in collaborazione con il Dr. Claudio Chillemi (ICOT, Latina (RM)) che mira ad eseguire un confronto tra diverse tecniche chirurgiche per la riparazione della cuffia dei rotatori. Lo studio clinico in questione durerà circa due anni: per questo motivo i dati analizzati in questo progetto di tesi provengono solo dal gruppo di pazienti acquisiti nella fase preoperatoria. Tutti i dati sono stati acquisiti utilizzando i sensori magneto-inerziali WISE (tecnologia proprietaria dell’azienda NCS Lab). Questo lavoro di tesi si propone, quindi, di valutare la ripetibilità del movimento in termini di coefficiente di correlazione multipla e di estrapolare alcuni parametri di interesse clinico come, ad esempio, i range di movimento (ROM) della scapola e dell’omero e il ritmo scapolo-omerale (SHR). Questi parametri sono stati poi caratterizzati da un punto di vista statistico al fine di valutare le differenze tra arto patologico e controlaterale. Sono state calcolate, inoltre, le prediction bands con lo scopo di descrivere le differenze tra arto patologico e controlaterale nella coordinazione scapolo-omerale dei pazienti.
Per quanto riguarda la ripetibilità del movimento, i risultati ottenuti in questo lavoro di tesi mostrano che la rotazione medio-laterale è caratterizzata da un eccellente CMC sia per l'arto patologico che per il controlaterale. Inoltre, sono state riscontrate differenze significative dal punto di vista statistico tra le distribuzioni dei range di movimento dell'arto patologico e controlaterale. Tali differenze sono state trovate anche per quanto riguarda il ritmo scapolo-omerale.