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1

Calle, Domínguez Jehannara. "Properties of Malanga Flours and their Use in Pastes and Gluten Free Breads." Doctoral thesis, Universitat Politècnica de València, 2021. http://hdl.handle.net/10251/168396.

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[ES] El uso de Colocasia esculenta (L.) Schott y Xanthosoma sagittifolium (L.) Schott como materia prima en forma de almidón o harina es una alternativa sostenible y nutritiva al trigo y otros granos. Esta alternativa permite a los agricultores minimizar las pérdidas después de su cosecha y garantizar la seguridad alimentaria ya que sus propiedades nutricionales, digestivas y saludables son reconocidas por la comunidad científica. Sin embargo, la información existente sobre este rizoma dirigida a su aplicación es bastante limitada. Esta tesis expone la caracterización funcional y tecnológica d
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Pillitu, Davide <1974&gt. "LA FAMIGLIA TACCÒ E IL PALAZZO DI CORMÒNS: STORIA, ARTE, ARCHITETTURA. SECOLI XVI – XVIII." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/17887.

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Il tema dello studio si focalizza sull'esame del settecentesco palazzo Taccò e sul suo apparato decorativo interno. L'edificio, situato nel centro storico della città di Cormòns, cospicua realtà socio economica della contea di Gorizia, costituisce uno degli episodi architettonico artistici più affascinanti dell'intero territorio comitale ed è strettamente legato alle vicende materiali della famiglia baronale dei Taccò. La puntuale analisi della documentazione relativa alla stirpe, reperita nel corso di una lunga ricerca archivistica tra Cormons e Gorizia, ha consentito di proporre un ipotesi d
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Pereira, Claudia Figueiredo. "Carbon monoxide, autophagy and cytoprotection in response to cerebral ischemia." Master's thesis, Faculdade de Ciências e Tecnologia, 2013. http://hdl.handle.net/10362/10836.

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Dissertação para obtenção do Grau de Mestre em Genética Molecular e Biomedicina<br>There is an increasing need for promoting neuroprotection against cerebral ischemia, which is the main cause of brain damage in adults. Astrocytes are the most abundant cells inboard the central nervous system (CNS), being known as key glial cell for promoting neuronal survival and homeostasis. It is more established in nowdays that astrocytic dysfunction contributes to neurodegenerative processes. Although, carbon monoxide is a well renown as a lethal and toxic gas due to its high affinity to hemoglobin, CO ex
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Pouyet, Thomas. "Cormery et son territoire : origines et transformations d'un établissement monastique dans la longue durée (8e-18e siècles)." Thesis, Tours, 2019. http://www.theses.fr/2019TOUR2006.

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L’objectif de cette recherche est de caractériser les aspects topographiques, fonctionnels et architecturaux de l’abbaye bénédictine de Cormery établie en Touraine, par la communauté de Saint-Martin de Tours en 791 et restée en fonction jusqu’à la Révolution française. Cette approche multi-scalaire du monastère s’appuie sur les sources textuelles et les nombreux vestiges en élévation qui incluent les bâtiments claustraux. La première partie de ce travail s’attache à analyser le contexte de fondation du monastère dans la vallée de l’Indre et tout particulièrement le lien avec la rivière. Dans u
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Gancedo, Marcelo. "EFEITO DO NITROGÊNIO, CALCÁRIO E GESSO AGRÍCOLA EM ALGUNS ATRIBUTOS DE UM LATOSSOLO E NO DESENVOLVIMENTO DE GLADÍOLO." UNIVERSIDADE FEDERAL DA GRANDE DOURADOS, 2007. http://tede.ufgd.edu.br:8080/tede/handle/tede/106.

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Made available in DSpace on 2016-02-26T12:59:37Z (GMT). No. of bitstreams: 1 MarceloGancedo.pdf: 341813 bytes, checksum: 7979c040bfdc034605ce046a6a950ead (MD5) Previous issue date: 2007-03-29<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>This work was developed in Gardening at UFMS (Universidade Federal de Mato Grosso do Sul) NCA (Núcleo Experimental de Ciências Agrárias), from September 2004 to February 2006 having the aim of valuating nitrogen, limestone and phosphogypsum over gladiolus development and over some chemical and physical characteristics of a dystroferri
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Daniel, Louis Broaddus III. "Spawning and ecology of early life stages of black drum, Pogonias cormis, in lower Chesapeake Bay." W&M ScholarWorks, 1995. https://scholarworks.wm.edu/etd/1539616624.

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During spring 1990 and 1991, ichthyoplankton surveys were conducted in lower Chesapeake Bay to estimate seasonal egg production, population biomass and the impact of predation by gelatinous zooplankton on early life stages of black drum, Pogonias cromis. Rearing experiments indicated that at least three species of sciaenid (silver perch, Bairdiella chrysoura; weakfish, Cynoscion regalis and P. cromis) were spawning in the survey area during both years. Specific identification of eggs based on previously published ranges of outside egg diameter (OED) were not reliable due to considerable overla
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Southam, Hannah. "Ruthenium-carbonyl carbon monoxide-releasing molecules (CORMs) as antimicrobial agents : a revised perspective." Thesis, University of Sheffield, 2017. http://etheses.whiterose.ac.uk/18379/.

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8

Van, Rooyen Anzel. "The effect of in vitro digestion on selected biological activities of Hypoxis sobolifera corms." Thesis, Nelson Mandela Metropolitan University, 2013. http://hdl.handle.net/10948/d1020058.

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In South Africa part of the cultural and religious beliefs of the African people is the use of traditional remedies to treat diseases. These remedies are obtained from medicinal plants (Steenkamp, 2003). One of the most frequently traded plants in the Eastern Cape is Hypoxis, commonly known as Afrika patat, or African potato. South African traditional healers instruct patients to brew the fresh Hypoxis corm as a tea and then ingest it (Steenkamp, 2006a). This prompted an investigation into the digestive stability of a traditionally prepared Hypoxis extract. The H. sobolifera extracts were dige
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Kohns, Marbod [Verfasser]. "UV-induzierte CO-Freisetzung aus Mangankomplexen (CORMs): Untersuchung der toxischen Eigenschaften in Säugerzellen / Marbod Kohns." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2015. http://d-nb.info/1077063415/34.

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Göderz, Anna-Lena [Verfasser]. "Synthese und Untersuchung von wirkortspezifischen enzymatisch aktivierbaren CO-freisetzenden Molekülen (ET-CORMs) / Anna-Lena Göderz." München : Verlag Dr. Hut, 2018. http://d-nb.info/1176251155/34.

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Roth, Patrick [Verfasser], and Ulrich [Gutachter] Schatzschneider. "Metalltricarbonyl-basierte CO-releasing molecules (CORMs): Variation der Freisetzungskinetik und Biokonjugation / Patrick Roth ; Gutachter: Ulrich Schatzschneider." Würzburg : Universität Würzburg, 2021. http://d-nb.info/1236547950/34.

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Ali, Salar. "Effects of carbon monoxide and carbon monoxide-releasing molecules (CORMs) as adjuvants to antibiotics on Escherichia coli." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/15187/.

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Antibiotic-resistant pathogenic bacteria pose a major, growing public health risk. Antibiotics affect specific targets so that bacteria may develop cognate resistance to the target site. To cope with antibiotic resistance, combinatorial therapies involving two (or more) antimicrobial agents may be useful for minimizing antibiotic resistance phenomena. It is, therefore, necessary to investigate other antimicrobial agents. Carbon monoxide-releasing molecules (CORMs) have been shown to exert antimicrobial actions on several bacterial species both in the laboratory and in animal models. The aims o
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Suchland, Benedikt [Verfasser], Matthias [Gutachter] Westerhausen, and Rainer [Gutachter] Beckert. "Eisencarbonylkomplexe für den Einsatz als potenzielle CO freisetzende Moleküle (CORMs) / Benedikt Suchland ; Gutachter: Matthias Westerhausen, Rainer Beckert." Jena : Friedrich-Schiller-Universität Jena, 2020. http://d-nb.info/1211670678/34.

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Suchland, Benedikt Verfasser], Matthias [Gutachter] [Westerhausen, and Rainer [Gutachter] Beckert. "Eisencarbonylkomplexe für den Einsatz als potenzielle CO freisetzende Moleküle (CORMs) / Benedikt Suchland ; Gutachter: Matthias Westerhausen, Rainer Beckert." Jena : Friedrich-Schiller-Universität Jena, 2020. http://d-nb.info/1211670678/34.

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15

Botov, Svetlana [Verfasser]. "Synthese und Evaluation von Dien-Tricarbonyleisen(0)-Komplexen als enzymatisch aktivierbare CO-freisetzende Moleküle (ET-CORMs) / Svetlana Botov." München : Verlag Dr. Hut, 2016. http://d-nb.info/1094117544/34.

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Popova, Marina. "Visible Light-Triggered Carbon Monoxide-Releasing Molecules." DigitalCommons@USU, 2019. https://digitalcommons.usu.edu/etd/7500.

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Carbon monoxide (CO) is now well established as one of the signaling molecules in higher organisms, including humans. Due to its physiological roles, CO is now accepted as a potential therapeutic agent. The use of CO gas has been studied in multiple clinical trials. Vasodilation, anti-inflammatory, anti-apoptotic, anti-proliferative and cytoprotective effects are just a few of the pharmacological actions attributed to CO gas in various models of diseases. Use of inhaled CO gas as a therapeutic has many limitations which necessitate the development of a new approach for CO delivery. In order to
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Romanski, Steffen [Verfasser]. "Synthese und Evaluation geschützter oxysubstituierter Dien-Fe(CO)3-Komplexe als enzymatisch aktivierbare CO-freisetzende Moleküle (ET-CORMs) / Steffen Romanski." München : Verlag Dr. Hut, 2013. http://d-nb.info/1033041610/34.

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Storz, Dennis [Verfasser], and Benito A. [Akademischer Betreuer] Yard. "Enzyme-triggered CO-releasing molecules (ET-CORMs): towards tissue-specific delivery of carbon monoxide / Dennis Storz ; Betreuer: Benito A. Yard." Heidelberg : Universitätsbibliothek Heidelberg, 2020. http://d-nb.info/1211258890/34.

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Annereau, Marcel. "Élaboration de nouvelles stratégies de traitement du cancer du foie par l'utilisation de molécules libérant du monoxyde de carbone (CORMs)." Electronic Thesis or Diss., Sorbonne université, 2024. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2024SORUS265.pdf.

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Ce projet de thèse s'inscrit dans le développement d'une nouvelle stratégie de traitement du cancer du foie. En effet, le cancer du foie est l'un des cancers les plus mortels au monde, sans traitement efficace jusqu'à présent. Dans ce projet, nous avons proposé d'utiliser le monoxyde de carbone (CO) comme alternative. Le CO est connu comme étant un gaz mortel, lui valant le surnom de « tueur silencieux » cependant, depuis une dizaine d'années, le CO est décrit comme étant un agent thérapeutique prometteur entre autres pour le traitement du cancer lorsqu'il est administré à des concentrations o
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Lorett, Velasquez Vaneza Paola Verfasser], Matthias [Akademischer Betreuer] Westerhausen, and Alexander [Akademischer Betreuer] [Schiller. "Synthesis of ruthenium and manganese carbonyl complexes : a search for new carbon monoxide releasing molecules (CORMs) / Vaneza Paola Lorett Velasquez. Gutachter: Matthias Westerhausen ; Alexander Schiller." Jena : Thüringer Universitäts- und Landesbibliothek Jena, 2014. http://d-nb.info/104709696X/34.

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21

Santos, Marino Filipe Alves dos. "Interacções de proteínas do plasma com potenciais fármacos: estudos 3D a nível molecular." Master's thesis, Faculdade de Ciências e Tecnologia, 2011. http://hdl.handle.net/10362/6238.

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Dissertação para obtenção do Grau de Mestre em Biotecnologia<br>Outrora considerado um produto tóxico, reconhecem-se, hoje, ao monóxido de carbono (CO) efeitos biológicos e terapêuticos (nomeadamente anti-inflamatórios); neste sentido, desenvolveram-se metodologias para a sua aplicação destacando-se as Moléculas Libertadoras de Monóxido de Carbono (CORMs). Perspectivando a passagem a fármacos, é indispensável elucidar os mecanismos de acção e de transporte no organismo que dependem, significativamente, das interacções estabelecidas com proteínas sanguíneas (hemoglobina, albumina e transferrin
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Wu, Jyh-fang, and 吳志方. "Studies on corm and cormel production in Gladiolus grandiflorus." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/51111519136857098030.

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碩士<br>國立臺灣大學<br>園藝學系<br>81<br>Corm and cormel production of gladioli was studied in southern part of Taiwan. The best time to harvest corms and cormels was two to four weeks after flowers harvesting when using No.3 medium-size corms to produce cut flowers and corms of gladiolus during winter in southern part of Taiwan.It was suggested to leave four leaves on stem at harvesting flowers to get both favorable-length stalks and large quantity corm production. ''Spic and Spic''was proved t
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Shen, Jian Hong, and 沈建宏. "Studies on corm production and dormancy physiology of cormel in gladiolus." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/67841162811177977469.

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Wu, Hsin-Yi, and 吳欣怡. "Effects of Ethrel and Cormlet Size on Sprouting, Growth and Development of Gladiolus." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/88336231960648703412.

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碩士<br>國立中興大學<br>園藝學系所<br>94<br>The study is about the effect of Ethrel on sprouting and development in the different cormel size of Gladiolus ’ Princess Margaret Rose’ cormlets from anther culture in vivo and in vitro. in order to accelerate the speed of breaking the physiological dormancy of the cormel, recover the growth, shorten the time of culture. The situation of dormancy of Gladiolus ’ Princess Margaret Rose’ cormlets from anther culture had been changed by the different cormlet size, the dormancy were strong in the small cormlte size, and were weak in the large one. The study result co
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Qian, Yap Yi, and 葉貽謙. "Ex-situ preservation of Nymphaea capensis seeds and Isoetes taiwanensis corms." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/5xqb88.

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碩士<br>國立清華大學<br>分子與細胞生物研究所<br>104<br>Nymphaea capensis is an aquatic plant which produces recalcitrant seeds. Its’ seeds were desiccation intolerant and metabolically active. Cryopreservation is suggested because the conventional methods could not provide a stable storage environment for the seeds. Vitrification pretreatment was used to avoid the formation of ice crystals in cryopreservation. This study showed that cryopreserved seeds which progressed 12 h and 18 h of plant vitrification solution 3 (PVS3) treatments brought the highest germination rate (66.7%) among various pretreatment period
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Roth, Patrick. "Metalltricarbonyl-basierte CO-releasing molecules (CORMs): Variation der Freisetzungskinetik und Biokonjugation." Doctoral thesis, 2021. https://doi.org/10.25972/OPUS-24017.

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Kohlenstoffmonoxid ist ein wichtiges kleines Signalmolekül das im menschlichen Körper durch die enzymatische Wirkung von Häm-Oxygenase (HO) auf Häm produziert wird. Für eine thera-peutische Anwendung werden Metallcarbonyl-Komplexe als CO-releasing molecules (CORMs) untersucht, die eine kontrollierte Freisetzung in biologischen Zielstrukturen erlauben. Dafür wird entweder die Ligandenperipherie ("drug sphere") modifiziert oder die CORMs an bio-molekulare Trägersysteme konjugiert. Im Rahmen dieser Arbeit stand dabei die lichtinduzierte Freisetzung von Kohlenstoffmonoxid aus Mangan(I)tricarbonyl-
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Santos, Marino Filipe Alves dos. "Structural and functional studies on the reactivity of CORMs with plasma proteins." Doctoral thesis, 2016. http://hdl.handle.net/10362/19026.

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Huang, Kuo-Ching, and 黃國清. "The effects of carbon monoxide releasing molecules (CORMs) on paraquat-induced pulmonary interstitial inflammation and fibrosis." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/h6yp5m.

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碩士<br>南臺科技大學<br>生物科技系<br>104<br>Paraquat (PQ) is a widely used herbicide in the world but highly toxic to both humans and animals. After ingestion, PQ is rapidly absorbed into the bloodstream and concentrates primarily in pulmonary tissue, and then develops into irreversible pulmonary fibrosis, which is the primary cause of death. Pulmonary fibrosis is characterized by fibroblast proliferation, myofibroblast differentiation, and deposition of extra-cellular matrix in the lung parenchyma. Carbon monoxide (CO) is toxic to humans and animals, recent studies suggest low dose, 10 to 500 ppm, CO has
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Soares, Nuno Ricardo Lucas. "Anti-inflammatory effect of carbon monoxide on the neuron-microglia bidirectional communication." Doctoral thesis, 2021. http://hdl.handle.net/10362/113414.

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RESUMO: Doenças neurológicas refere-se a qualquer tipo de patologia que afecta o cérebro, espinal medula e sistema nervoso periférico. Entre outras, podemos identificar doenças como o acidente vascular cerebral (AVC), epilepsia, doenças psiquiátricas, demência, infecções neurológicas e tumores. A Organização Mundial da Saúde (OMS) estima que, em 2030, quase 8 mil milhões de pessoas irão morrer devido a este tipo de doenças. A fisiopatologia e progressão dos distúrbios do Sistema Nervoso Central (SNC) são, na maior parte das vezes, multifatoriais e mal compreendidos, tornando um tratament
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Mendes, Ana Sofia Soares. "Carbon Monoxide Releasing Molecules - towards a novel antimicrobial therapeutic drug." Master's thesis, 2018. http://hdl.handle.net/10362/130065.

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"Carbon monoxide releasing molecules (CORMs) are carbonyl organometallic complexes that liberate controlled amounts of carbon monoxide, which is a signalling and cytoprotective molecule important in human physiology and pathophysiology. Several studies in animals have shown that CORMs are beneficial in the treatment of cardiovascular diseases, inflammation and organ protection. Additionally, CORMs present antimicrobial properties. (...)"
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Wang, Danzhu. "From "Click" to "Click and Release", Using Inverse Electron Demand Diels-Alder Reaction for Chemical and Medicinal Applications." 2014. http://scholarworks.gsu.edu/chemistry_diss/96.

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Substituted tetrazines have been found to undergo facile inversed electron demand Diels-Alder reactions with “tunable” reaction rates. By varying the substituents on tetrazine, cycloaddition rate variations of over 200 fold have been achieved with the same dienophile. Coupled with the availability of different dienophiles, such as norbornene, the reaction rate difference can be over 14,000 folds. These substituted tetrazines can be very useful for selective labeling under different conditions. This finding paves the way to utilize tetrazine conjugation reactions for not only DNA but also stage
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Berrino, Emanuela, Claudiu Supuran, Alessandro Mugelli, and Fabrizio Carta. "Carbonic Anhydrase Inhibitors: Versatile Agents for the Treatment of Human Diseases." Doctoral thesis, 2020. http://hdl.handle.net/2158/1188882.

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The Carbonic Anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes expressed in almost all living organisms. Being one of the main actors in pH regulation and in the maintenance of proper concentrations of CO2, the dysruption of the activity of such enzymes, by means of adequate modulators, is a validated strategy for the treatment of human affecting pathologies and for the eradication of etiological agents (i.e. pathogenic bacteria, fungi and protozoa). In addition, CA-based biotechnological applications (i.e. CO2 capture) may benefit from modulation of the enzymatic activity. CA Inhibit
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Swart, Pierre Andre. "Propagation of Romulea species." Thesis, 2012. http://hdl.handle.net/10413/8324.

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Romulea is a genus with numerous attractive and endangered species with horticultural potential. This genus in the Iridaceae has its centre of diversity in the winter-rainfall zone of South Africa. This thesis uses ecophysiological and biotechnological techniques to investigate the physiology behind the propagation of some species in this genus. The ecophysiological techniques of soil sampling and analysis and germination physiology were used to determine the natural and ex vitro growth and development requirements of these plants, while biotechnological techniques are used to determine the in
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Mtshali, Ntombizamatshali Prudence. "Role of light and temperature in the flowering of Watsonia species." Thesis, 2006. http://hdl.handle.net/10413/5503.

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The role of light and temperature on flowering of South African Watsonia species were evaluated to assess the potential for this genus as a commercial flower crop. Species were selected that represent different climatic regions of South Africa, with the aim of understanding how ecologically distinct species perform under cultivation. The four selected species were W. borbonica and W. tabularis (winter-rainfall area), W. angusta (shared rainfall) and W. pillansii (summer-rainfall area). In order to establish the optimum temperature required for flowering, plants were exposed for 12 weeks to thr
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Marinho, Andreia Daniela Pereira. "Desenvolvimento e Caracterização de Nanoagentes para a Artrite Reumatoide." Master's thesis, 2018. http://hdl.handle.net/10362/52579.

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A artrite reumatoide (AR) é uma patologia crónica e incapacitante com grande impacto na qualidade de vida dos doentes. Caracteriza-se pela existência de inflamação nas articulações podendo mesmo levar à destruição do tecido articular. Afeta cerca de 0.5 a 1% da população mundial, verificando-se que tem maior incidência em mulheres do que em homens. Não é conhecida uma cura para a doença, pelo que é fundamental uma terapia mais eficaz para que se consiga controlar os sintomas e se possível retardar o avanço da doença. O monóxido de carbono (CO) em tempos visto apenas como um agente tóxico, at
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Oliveira, Ana Rita Martins Lourenço de. "Complexos Organometálicos: caracterização preliminar de compostos de vanádio e de moléculas libertadoras de CO como potenciais fármacos." Master's thesis, 2015. http://hdl.handle.net/10362/16091.

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Vários complexos metálicos têm sido explorados visando uma melhoria de atuais tratamentos das mais variadas doenças. Os compostos de vanádio apresentam uma capacidade de mimetizar a ação da insulina, insurgindo-se assim como uma aposta no tratamento da doença Diabetes mellitus. O monóxido de carbono (CO), outrora visto como apenas um agente tóxico, atualmente é explorado pelas suas capacidades anti-inflamatórias, tendo-se desenvolvido moléculas libertadoras de CO, os CORMs, de modo a tirar partido dos seus efeitos biológicos. Com vista a determinar a formação de aductos entre os complexos org
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