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Zeitschriftenartikel zum Thema "Colposcopy – methods"

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Rema, Prabhakaran Nair, Aleyamma Mathew und Shaji Thomas. „Performance of colposcopic scoring by modified International Federation of Cervical Pathology and Colposcopy terminology for diagnosing cervical intraepithelial neoplasia in a low-resource setting“. South Asian Journal of Cancer 08, Nr. 04 (Oktober 2019): 218–20. http://dx.doi.org/10.4103/sajc.sajc_302_18.

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Abstract Introduction: Colposcopy is a tool to evaluate women with cervical pre-cancer and cancer. To interpret the colposcopic findings, various scoring systems are used but with inter observer variations. To improve the quality of colposcopy, International Federation of Cervical Pathology and Colposcopy (IFCPC) has introduced a colposcopic nomenclature in 2011. Colposcopic scoring helps to select patients who need treatment for cervical intraepithelial neoplasia. Aim of the Study: The study aimed to evaluate the agreement between colposcopic diagnosis with the modified IFCPC terminology and cervical pathology in patients with abnormal screening tests and to assess the utility of this colposcopic scoring system in low resource settings. Methodology: Patients with abnormal screening tests who underwent colposcopic assessment in the department of Gynaecological oncology were included in the study. Colposcopic scoring was done by the modified IFCPC nomenclature. The results were compared with cytology and the final histopathology. Results: 56 patients were included in the study. The colposcopic scoring when compared to histopathology showed agreement in 65.7% which indicated the agreement was substantial and was statistically significant (P = 0.0001). With cytology the colposcopic score showed agreement in 35.6% indicating a fair agreement and this was also statistically significant (P = 0.001). Conclusion: Colposcopic scoring by modified IFCPC 2011 criteria showed substantial agreement with cervical histopathology. Compared to traditional methods, 2011 international terminology of colposcopy could improve colposcopic accuracy.
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Verma, Indu, Pratibha Pundhir, Tejinder Kaur, Veena Jain und Dinesh Sood. „Evaluation of Reid’s Combined Colposcopic Index as a predictor of cervical intraepithelial lesion“. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, Nr. 9 (27.08.2018): 3724. http://dx.doi.org/10.18203/2320-1770.ijrcog20183784.

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Background: Carcinoma cervix is the commonest cancer among women worldwide and in India it accounts for 80% of all genital cancers. Screening methods include cervical cytology, human papilloma virus testing and colposcopy. Objective of present study was to evaluate suspicious cervix colposcopically using Reids Colposcopic Index (RCI) and to correlate RCI with histopathological findings.Methods: This was a prospective cross sectional study done on 125 women with clinical diagnosis of suspicious cervix. Colposcopy was performed and grading of the disease was done according to RCI. Positive cases were subjected to cervical biopsy and endocervical curettage was performed in unsatisfactory colposcopy.Results: Colposcopy was done on 125 women with suspicious cervix. Out of 125, sixty two showed abnormal colposcopic findings which were graded according to RCI into Low grade disease predicting histological diagnosis of CIN1 in 47, Intermediate grade disease predicting histological diagnosis of CIN1/2 in 11 and High grade disease predicting histological diagnosis of CIN2/3 in 4 women. Colposcopy of one women suggested invasive carcinoma and was confirmed on histopathology to be microinvasive squamous cell carcinoma. Six women with unsatisfactory colposcopy showed benign histopathology. Sensitivity, specificity, predictive value and false negative rate of colposcopy for invasive disease was 50%, 100%, 100% and 1.60% respectively with 98.40% diagnostic accuracy. Colposcopic diagnosis of invasive disease and histopathology report showed 100% correlation.Conclusions: Correlation between RCI and histopathology was good. Predictive accuracy of colposcopy increased with increasing severity of disease.
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Sinha, Mridu, Jai Kishan Goel, Shashi Bala Arya, Jayanti Kar, Bahar Kohli und Isha Tapasvi. „Comparison of Pap Smear and Colposcopy in Detection of Premalignant Lesions of Cervix“. Journal of SAFOMS 2, Nr. 1 (2014): 5–8. http://dx.doi.org/10.5005/jp-journals-10032-1023.

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ABSTRACT Objective Comparison of papanicolaou (pap) smear and colposcopy in detection of premalignant lesions of cervix. Materials and methods A prospective clinical study was conducted in a tertiary care referral institute in 100 symptomatic, sexually active women of 20 to 60 years. All women were subjected to pap smear, colposcopy and cervical biopsy to confirm the diagnosis. Results Out of 49 positive on pap smear, 24 were true positives and 25 were false positives. Out of 51 negative pap smear findings, 45 were true negatives and 6 were false negatives. Thirty percent women had positive histopathology and colposcopic findings. Forty percent women had normal colposcopy with negative histopathology whereas 30% had positive colposcopic findings but negative histopathology. Nineteen percent of women with negative cytology were positive on colposcopy and histopathology. Conclusion Pap smear had a sensitivity of 80% and a specificity of 64.29% with positive predictive value of 48.98% and negative predictive value of 88.24% while sensitivity and specificity of colposcopy were 100 and 57.14% respectively and positive predictive value and negative predictive value of colposcopy were found to be 50 and 100% respectively. How to cite this article Kohli B, Arya SB, Goel JK, Sinha M, Kar J, Tapasvi I. Comparison of Pap Smear and Colposcopy in Detection of Premalignant Lesions of Cervix. J South Asian Feder Menopause Soc 2014;2(1):5-8.
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Omeragić, Feđa, Azur Tulumović, Ermina Iljazovic, Amela Adzajlic, Alija Suko, Larisa Mešić-Đogic und Vladimir Perendija. „Use of colposcopy for detection of squamous intraepithelial lesions“. Journal of Health Sciences 4, Nr. 2 (29.08.2014): 72–76. http://dx.doi.org/10.17532/jhsci.2014.162.

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Introduction Pap smear, the main tool of cervical cancer screening is not always available, but some patients are in urgent need for proper diagnostic. Aim of this article was to investigate accuracy of colposcopy for detection of squamous intraepithelial lesions of low or high grade (LGSIL, HGSIL) and to promote colposcopy as useful tool for detection of patients in need for immediate further diagnostics. Methods Prospective multicentric study performed in B&H in 2012 -2013 included 87 patients with colposcopic images related to squamous intraepithelial lesion (SIL) who formed experimental group: 56 patients with colposcopic images related to LGSIL and 31 patients related to HGSIL. Control group included 50 patients without colposcopic abnormalities. To test accuracy of colposcopy, PAP smear and histology were used. For statistical analysis χ2 was used.Results 94.5% patients in experimental group had abnormal PAP test: 64.3% correlated to LGSIL (χ2= 60.48 P < 0.0001), while 64.5% correlated to HGSIL (χ2 = 54.23 P<0.0001) Odds Ratio = 490; 95% CI = 42.024 to 5713.304). HGSIL was confirmed in 27 (87%) cases by histology (CIN II /CIN III). There were no statistically significant differences between colposcopic finding and histology results (Yates-corrected χ2 = 0.33 P = .5637)Conclusions This study showed high level of correlation between colposcopy and PAP results (63-64%) and to histology for HGSIL (87%). In absence of PAP test colposcopy could be used to select patients in need for biopsy.
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Desai, BR, PR Malur, Dalal Anita, Durdi Geeta, Sherigar Bhavana und Gupta Pallav. „Sequential Screening with Cytology and Colposcopy in Detection of Cervical Neoplasia“. Journal of South Asian Federation of Obstetrics and Gynaecology 1, Nr. 3 (2009): 45–48. http://dx.doi.org/10.5005/jp-journals-10006-1009.

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ABSTRACT Background Pap smear is the most commonly used screening test for cervical cancer, however it has disadvantage of having low sensitivity. Colposcopy has higher sensitivity as compared to Pap smear but low specificity. Sequential screening with both Pap smear and colposcopy can overcome these problems. Aim The study was aimed to find out the diagnostic efficacy of both Pap smear and colposcopy. It was also intended to find out the advantages of sequential use of Pap smear and colposcopy in screening for cervical cancer. Design It was a cross-sectional study conducted in colposcopy clinic of KLE's Dr. Prabhakar Kore Hospital and MRC, Belgaum from November 2006 to September 2008. Material and methods A total of 190 patients with complaints of postcoital bleeding, intermenstrual bleeding, postmenopausal bleeding, persistent vaginal discharge or those found to have an unhealthy cervix on per speculum examination were included in the study. In all the 190 cases Pap smear, colposcopic evaluation and colposcopic directed biopsy were performed. Statistical analysis Sensitivity, specificity, positive predictive value, negative predictive value of both Pap smear and colposcopy were calculated with histopathology as a gold standard, keeping LSIL as a disease threshold for test positivity. Results Pap smear was positive in 14.21% (27/190) cases, colposcopy was positive in 37.89% (72/190) cases. Biopsy confirmed LSIL and higher lesions in 31.57% cases. The sensitivity, specificity, positive predictive value and negative predictive value of Pap smear were 41.66%, 96.92%, 86.21% and 78.26% respectively and 80%, 81.54%, 66.66% and 89.83% respectively for colposcopy. Combined colposcopy and Pap smear could accurately diagnose 53/60 biopsy confirmed cases of LSIL and higher lesions with an accuracy of 88.33%. Conclusion Sequential use of Pap smear and colposcopy in screening for cervical cancer increases the accuracy of the test.
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Gyawali, P., S. R. KC und S. Ghimire. „Role of Colposcopy in Detection of Dysplastic Cervical Lesion as a Screening Tool“. Journal of Global Oncology 4, Supplement 2 (01.10.2018): 33s. http://dx.doi.org/10.1200/jgo.18.51300.

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Background: Age standardized cervical cancer incidence rate in Nepal is 19.2/100,000 woman, compared with 14.0 worldwide. Similarly, mortality rate is 12.0 women which is significant in comparison with 6.8 worldwide. Cervical intraepithelial neoplasm is a precursor lesion, having high transformation rate into the cervical carcinoma. Data clearly indicates that CIN 2 and 3 has more progression into cervical carcinoma. Despite the fact that Papanicolaou test has remained an important tool in the screening for cervical cancer and has contributed in significant decrease in cervical cancer, sensitivity and specificity of conventional Papanicolaou test is quite low. Colposcopy is visual inspection of cervix under magnification. Study revealed that the positive predictive rate of the colposcopic impression is better as the cervical lesion is more severe. Aim: To find out the significance of colposcopy in the detection of dysplastic cervical lesions and possible use of this method as a screening tool. Methods: This is an observational study done at Cancer Care Foundation, Nepal done from a period of January 2015 to February 2018. Permission was obtained from ethical committee and written consent was obtained from the patients. All the patients suspected having dysplastic or invasive lesions or in whom colposcopy-guided biopsy was performed; were included in the study. Relevant data were collected which included age, colposcopic diagnosis, histopathological diagnosis. Data were entered into Microsoft Excel and statistical analysis was done from statistical package SPSS 21. Results: 6109 females were screened through colposcopy. Out of these 900 patients underwent colposcopy-guided biopsy for being suspected of dysplastic lesions or inflammatory lesions. Mean age of females was 40.65 years. With colposcopy, 407 (45.2%) were suspected to have low grade lesion, followed by 401 (44.6%) high grade lesion and 15 (1.7%) carcinoma. Nonneoplastic lesions were suspected in 77 (8.6%) females. In the histopathological examination low grade dysplasia was observed in 403 (44.8%) followed by 250 (27.8%) high grade dysplasia and 8 (0.9%) carcinoma in-situ or invasive carcinoma. Similarly, 239 (26.6%) patients had nonneoplastic lesions. In colposcopy, high grade lesions were suspected more frequently in females of 41-50 years age group than in 31-40 years age group ( P < 0.01). Correlation between increasing age and dysplastic lesions were also observed ( P < 0.05). There was significant correlation between colposcopic diagnosis and histopathological diagnosis with a P value < 0.01. The sensitivity of colposcopy to diagnose dysplastic lesions were high 96.44% with positive predictive value of 62.65%. The specificity of colposcopy to diagnose various grades of dysplastic lesions is 34.98%. Conclusion: Colposcopy is highly sensitive method of screening dysplastic cervical lesions and should be used more frequently as a screening purpose.
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Katz, Leticia Maria Correia, Alex Sandro Rolland Souza, Juliana Melo de Moraes Guerra und Melania Maria Ramos Amorim. „Is it necessary to repeat cervical cytology at the tie of a colposcopy?“ Revista Brasileira de Saúde Materno Infantil 12, Nr. 3 (September 2012): 319–26. http://dx.doi.org/10.1590/s1519-38292012000300011.

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OBJECTIVES: to evaluate whether repeating Papanicolaou smear testing at the time of colposcopy improves agreement between cytology and histopathology in the diagnosis of cervical cancer. METHODS: this cross-sectional study included 397 women referred for colposcopic evaluation following an abnormal cervical smear test. The cytology was repeated at the time of the colposcopy using a conventional medium. The two cytology tests were compared with each other and with the histopathological findings obtained by colposcopy-directed biopsy. The 2001 Bethesda system and the WHO 1994 classification were used for reporting cytology and histology results. The kappa coefficient was used to determine the agreement between methods. RESULTS: the comparison between the initial cytology findings and cytology performed at the time of colposcopy revealed a kappa of 0.297 (95%CI: 0.235-0.359), indicating a fair degree of agreement. When the results of the initial cytology were compared with histopathology, a kappa of 0.261, considered to represent a fair degree of agreement, was obtained (95%CI: 0.181-0.340). A kappa of 0.408, considered to represent moderate agreement, was found when the second cytology findings were compared with the histopathology (95%CI: 0.332-0.485). CONCLUSIONS: the agreement between cytology and histology improved when cytology was repeated at the time of colposcopy, following an initial abnormal test.
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Newman, Haley, Jilin Hu, Xiao Li, Jing He, Leslie Bradford, Songmei Shan, Xiaomei Wu et al. „Evaluation of portable colposcopy and human papillomavirus testing for screening of cervical cancer in rural China“. International Journal of Gynecologic Cancer 29, Nr. 1 (Januar 2019): 23–27. http://dx.doi.org/10.1136/ijgc-2018-000006.

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ObjectiveTo evaluate the use of a portable, rechargeable colposcope combined with human papillomavirus (HPV) testing, as compared with HPV testing alone, for screening of cervical cancer and pre-cancerous lesions.MethodsThis was a cross-sectional study among 488 women in Baoshan County, Yunnan. The women underwent HPV testing followed by Gynocular portable colposcopy with visual inspection with acetic acid. Obvious lesions were biopsied. If portable colposcopy testing was negative but HPV testing was positive, the women underwent follow-up testing with thin-prep cytology and traditional colposcopy. Cervical biopsies were performed for any abnormalities. Histopathology was followed up with diagnosis and treatment.ResultsAmong 488 women screened with portable colposcopy, 24 women underwent biopsy based on positive colposcopy screening. Of these 24 women, three were HPV positive and 21 were HPV negative. Five women had cervical intra-epithelial neoplasia (CIN) I and one had advanced cervical cancer. Forty-six women tested positive for HPV. Three of these women had screened positive on preliminary colposcopy, with one positive for CIN III/squamous cell carcinoma and one woman with CIN I. Forty-three women underwent follow-up testing with thin-prep cytology. Two women had atypical squamous cells of undetermined significance and five had low-grade squamous intra-epithelial lesions and were biopsied; three women had CIN I, one had CIN II and one had CIN III. HPV testing and portable colposcopy was more sensitive but slightly less specific than portable colposcopy or HPV testing alone.ConclusionWhile HPV testing has high sensitivity and specificity for the detection of pre-cancerous and cancerous lesions and portable colposcopy has lower specificity, both methods of detection have low positive predictive value and high negative predictive value. In tandem, HPV testing and portable colposcopy had higher sensitivity for detection among women who underwent biopsies. In clinical practice, portable colposcopy was an effective, easy and affordable tool to transport to villages where cytology is not currently feasible.
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Hilal, Ziad, Clemens Tempfer und Günther Rezniczek. „Treatment of Cervical Dysplasia by Clinicians Who Perform Colposcopy in German-speaking Countries – a Questionnaire-based Study“. Geburtshilfe und Frauenheilkunde 79, Nr. 02 (Februar 2019): 189–97. http://dx.doi.org/10.1055/a-0828-7831.

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Abstract Introduction In connection with the reorganisation of cervical carcinoma screening, the importance of colposcopy as an integral part of the planned series of clarification testing will greatly increase. Quality standards for performing the colposcopic examination should therefore be defined in detail. A precondition for this is surveying the current standard in clinical practice. The objective of this study was to evaluate the current practice of colposcopy and conisation in Germany by means of a questionnaire aimed at gynaecologists who perform colposcopies in order to document the actual therapeutic standard of treatment of cervical dysplasia. Materials and Methods Gynaecologists were invited via e-mail or during events to participate in a web-based survey. The questionnaire contained 38 questions on management before, during and after the examination as well as questions on the technical implementation of colposcopy and conisation. Results From February 2018 to April 2018, 961 e-mails were sent. A response was received in 197 cases (response rate 20.5%). Responses were received for another 40 questionnaires during events (response rate approx. 80%). After taking the inclusion criteria into account, 160 questionnaires were evaluated. The majority of those surveyed take an average of 2 cervical biopsies (67.3%) and nearly all of those surveyed (94.5%) do not use any local anaesthetic. As a standard method for removing cervical precancerous cells, most of the physicians surveyed perform a loop excision with the electrosurgical loop (91.2%) under colposcopic visualisation (61.2%) under general anaesthesia (92.5%). Postoperative bleeding prophylaxis by means of tamponade is performed only in 27.6% of all cases. Conclusion A differential colposcopy with two colposcopically targeted biopsies and treatment with the electrosurgical loop are the methods most frequently used by clinicians who perform colposcopy in Germany. A uniform procedure should be defined in detail within the scope of directives or guidelines.
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Sharma, Akanksha, Saritha Shamsunder, Niti Khunger, Geetika Khanna und Vijay Zutshi. „CHRONIC VULVAL SYMPTOMS: COMPARISON OF VARIOUS DIAGNOSTIC METHODS“. International Journal of Advanced Research 9, Nr. 02 (28.02.2021): 310–14. http://dx.doi.org/10.21474/ijar01/12448.

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The aim of our study was to compare the various diagnostic modalities for evaluation of chronic vulval symptoms. We studied 100 women presenting with chronic vulval symptoms who underwent examination of vulva with low magnification, scrape cytology, colposcopy & directed biopsy. The overall sensitivity and specificity for detecting vulvar lesions was 29.87% and 100% with low magnification 58.44% and 13.04% with cytology 77.92 % and 17.39 % with colposcopy. We concluded that clinical examination with or without magnification can detect most of the neoplastic lesions. Colposcopy and cytology have high negative predictive value and provide reassurance in absence of disease.
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Dissertationen zum Thema "Colposcopy – methods"

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Denny, Lynette Ann. „Does colposcopically directed punch biopsy reduce the incidence of negative LLetz?“ Thesis, University of Cape Town, 1994. http://hdl.handle.net/11427/26241.

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Maringa, Vusumuzi David. „The performance of the reid colposcopic index and swede score:predicting CIN in women living with HIV-1 in South Africa“. Thesis, 2019. https://hdl.handle.net/10539/28177.

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A research report submitted to the Faculty of Health Sciences, University of the Witwaters-rand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Med-icine in Obstetrics and Gynaecology. Johannesburg 2019
Background and objectives Cervical cancer can be prevented by screening and treatment of cervical cancer precursor lesions. Women with an abnormal Pap smear are referred to colposcopy for diagnosis and are then treated immediately in many South African colposcopy clinics. Hence accurate colposcopic diagnosis is important. The aim of this study was to determine the accuracy of diagnosing cervical intraepithelial neoplasia with either the Reid Colposcopic Index or the Swede score in HIV infected women. The components of the Reid colposcopic index are acetowhiteness, margins, vascular patterns and iodine staining. The Swede score has all the components of the Reid score with the addition of lesion size as a fifth compo-nent. Methods This was a secondary data analysis of the South African arm of the “HPV in Africa Research Partnership (HARP) study” comparing different screening tests in the prevention of cervical cancer in HIV infected women. Women were recruited from primary health care clinics and HIV treatment centres in Hillbrow, Johannesburg. All women had a Pap smear, Human papil-lomavirus testing, and visual inspection with lugol’s iodine and with acetic acid. All women with any positive screening test were referred to colposcopy. At colposcopy a four-quadrant biopsy and directed biopsies of any visible lesions were performed. The colposcopist rec-orded the colposcopy findings using the Swede score. For this study, the information from the Swede score was used to determine the Reid colposcopy index. Data was extracted from the HARP study database. Results A total of 624 women were eligible for the study in the South African arm, only 577 women were included for this study. The mean age was 34 years (SD±5.89). Antiretroviral therapy was used by 370 (64%) women. Abnormal Pap smears were found in 484 (88%) women, VIA was positive in 162 (28%), VILI was positive in 219 (37%) and HR HPV DNA was found in 374 (65%) women re-spectively. Histological findings showed that 263 (46%) of the women had no CIN, 185 (32%) had CIN 1, 76 (13%) had CIN 2 and 53 (9%) had CIN 3. The Swede score of 5 had a sensitivity of 72.9%, specificity of 71.9%, PPV of 42.7%and NPV of 90.2% respectively. A Reid score of 4 had a sensitivity of 72.9%, specificity of 69.4%, PPV of 40.7% and NPV of 89.9%. In comparison, the Area under the curve was higher for the Swede score compared to the Reid and this differ-ence was statistically significant. Conclusion This study shows that the Swede score when compared to the Reid score performs better in terms of accuracy for predicting CIN≥2 lesions. The addition of the lesion size has been shown to have an added advantage in the performance of the scoring. Both scores also demonstrated flexibility. There is a higher likelihood of HIV infected women to be referred for colposcopy as they have a higher incidence of cervical cancer precursor lesions. There was no difference in the performance of the Swede or Reid score by antecedent Pap smear and there was no difference in colposcopy findings on women with the presence of HR-HPV or no HR-HPV.
E.K. 2019
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Bücher zum Thema "Colposcopy – methods"

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Modern colposcopy: Textbook & atlas. 3. Aufl. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins Health, 2012.

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Saloney, Nazeer, Hrsg. Colposcopy: A practical guide. 2. Aufl. Cambridge, UK: Cambridge University Press, 2012.

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Manual of microcolposcopy. Amsterdam: Elsevier, 1988.

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Singer, Albert. Lower genital tract precancer: Colposcopy, pathology, and treatment. 2. Aufl. Malden, MA, USA: Blackwell Science, 2000.

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M, Monaghan John, Hrsg. Lower genital tract precancer: Colposcopy, pathology, and treatment. Cambridge, Mass: Blackwell Science, 1994.

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author, Khan Ashfaq M., Hrsg. Singer & Monaghan's cervical and lower genital tract precancer: Diagnosis and treatment. Chichester, West Sussex: John Wiley & Sons, Ltd, 2014.

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S, Apgar Barbara, Brotzman Gregory L und Spitzer Mark, Hrsg. Colposcopy, principles and practice: An integrated textbook and atlas. 2. Aufl. Philadelphia: Saunders/Elsevier, 2008.

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Singer, Albert, Swee Chong Quek und John M. Monaghan. Lower Genital Tract Precancer: Colposcopy, Pathology and Treatment. Wiley & Sons, Incorporated, John, 2008.

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Singer, Albert, und John M. Monaghan. Lower Genital Tract Precancer: Colposcopy, Pathology and Treatment. 2. Aufl. Blackwell Publishing Limited, 2000.

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Spitzer, Mark, Barbara S. Apgar, Gregory L. Brotzman und Donna D. Ignatavicius. Colposcopy: Principles and Practice: An Integrated Textbook and Atlas. Saunders, 2002.

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Buchteile zum Thema "Colposcopy – methods"

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Priya, Swati, und Krishna Agarwal. „Visual Inspection Methods for Cervical Cancer Prevention“. In Colposcopy of Female Genital Tract, 33–41. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-1705-6_3.

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Heinzl, S. „Destructive Methods in the Treatment of Cervical and Vulval Intraepithelial Neoplasias“. In Colposcopy in Diagnosis and Treatment of Preneoplastic Lesions, 71–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-72761-0_16.

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Gupta, Nidhi, und Mukesh Chandra. „Methods for Evaluating Cervix“. In Colposcopy Made Easy—A Hands on Manual for Practising Doctors and Postgraduates, 62. Jaypee Brothers Medical Publishers (P) Ltd., 2009. http://dx.doi.org/10.5005/jp/books/10156_7.

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Konferenzberichte zum Thema "Colposcopy – methods"

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Mangla, Akanksha, und Renuka Sinha. „Role of complementary cytology, colposcopy and histopathology in detecting premalignant and malignant lesions of cervix“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685253.

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Objective: Cervical cancer is the second most common gynecologic malignancy worldwide. India alone accounts for one fifth of total number of cases worldwide. The aim of our study was to calculate sensitivity, specificity, positive predictive value, negative predictive value, false positive rate and false negative rate of complementary cytology and colposcopy with histopathology as gold standard for detection of premalignant and malignant cervical lesions. Methods: A cross sectional study was conducted at Vardhman Mahavir Medical College and Safdarjung hospital, Delhi, India. 100 non pregnant females with complaint of post coital or irregular vaginal bleeding and those who had unhealthy cervix on visual inspection were included in study. Results: Colposcopy exhibited a high degree of accuracy in diagnosis of high grade lesions. Overall sensitivity of cytology was 50% whereas that of colposcopy was 83.3%. Cytology had specificity of 93.4% whereas colposcopy had specificity of 89.4%. 100% of high grade and invasive cancers on colposcopy were associated with similar findings on histology. The degree of agreement between cytology and colposcopy with histology was significant (p<0.001). Conclusion: Colposcopy is sensitive method as compared to cytology, especially in the higher grade lesions and combination of both methods appears to be of higher diagnostic importance.
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Hsu, Elizabeth, Brandon Gallas und Jose Jeronimo. „METHODS FOR MRMC ROC ANALYSIS AND COMPONENTS-OFVARIANCE MODELING USING COLPOSCOPY IMAGES“. In 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro. IEEE, 2007. http://dx.doi.org/10.1109/isbi.2007.357089.

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Sharma, Akanksha, Saritha Shamsunder, Geetika Khanna, Neeti Khunger und Vijay Zutshi. „Chronic vulval problems: A gynaecologist’s perspective“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685355.

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Introduction: Chronic vulval symptoms are common complaints in women seeking health care and can significantly interfere with a woman’s sexual function and sense of well being. Many practitioners feel diagnostically challenged, particularly by chronic or recurrent forms of vulval disease. The aim of this study was to assess the role of various diagnostic modalities in evaluation of chronic vulval symptoms. Methods: Between August 2012 and February 2014, 100 women presenting with chronic vulval symptoms (i.e. ≥ 3 months duration) were evaluated. All of them had a thorough clinical history taken including use of vulval washes and creams, a general and gynaecological examination. Patients having chronic vaginal discharge in addition had urethral, vaginal and cervical smear and culture. All women had a careful examination of the vulva with and without magnification. Vulval scrape cytology was taken after moistening the vulva with normal saline and stained by Pap stain. Colposcopy of the vulva was then carried out after applying 5% acetic acid and 1% toluidine blue dye. Vulval biopsy was taken from suspicious areas on colposcopy and further management was based on histopathology report. Results: The mean age of women in our study was 43.57 years (range 22-80 years.), 70% women were pre-menopausal and 30% were post-menopausal. The mean duration of symptoms was 1.625 years (range 6 months - 15 years) and atypical vulval hygiene practices (excessive washing with soaps) was used in 77% of women. The commonest presenting complaint was pruritus in 92% of women; visible lesions on vulva were seen in 20%, pain in 6% and burning sensation in vulva in 5% of women. The histopathology was abnormal in 77 patients; the most common histopathological finding was non-neoplastic epithelial disorders in 64 women {Squamous cell hyperplasia (n=52), Lichen Sclerosus et atrophicus (n=6), other dermatoses including lichen Planus (n=6)}. Vulvar Intra-epithelial Neoplasia (VIN) was seen in 6 patients, 5 were squamous type VIN and 1 was non-squamous type (Paget’s disease). Squamous cell carcinoma was seen in 3 patients; malignant melanoma, benign appendiceal tumor, angiofibroma and neurofibroma in 1 patient. Examination without magnification had sensitivity of 25.97% and with magnification was 29.87% and specificity was 100% for both of them. Cytology had sensitivity and specificity of 75.32% and 86.95% respectively and sensitivity and specificity of colposcopy was 77.92% and 17.39% respectively. Conclusion: Clinical examination with and without magnification had low sensitivity but were highly specific in diagnosing vulvar lesions. A normal vulval smear and colposcopy have a high negative predictive value and are very reassuring. Colposcopy and biopsy is the gold standard for diagnosis, however clinical examination with naked eyes and magnifying glass are invaluable and can diagnose most of the neoplastic lesions.
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Tyagi, Natasha, Amita Suneja, Kiran Mishra, Sandhya Jain, Neelam B. Vaid und Kiran Guleria. „Comparison of Keyes punch biopsy instrument with cervical punch biopsy forceps for diagnosing cervical lesions“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685286.

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Aims: To assess the feasibility and efficacy of Keyes punch biopsy instrument (KP) in diagnosing cervical lesions and compare it with cervical punch biopsy forceps (CP). Methods: 75 women having adequate colposcopy with abnormal transformation zone were included and paired colposcopic directed biopsies were taken using KP followed by CP from the same target area. The outcome parameters were compared using paired t-test, Wilcoxon signed rank test and McNemar test. Results: It was feasible in all cases to take cervical biopsy with KP and CP. Volume of gross specimen obtained by KP was less than CP (0.076±0.097 vs 0.101±0.156 cm3, p=0.061), however on microscopic examination, mean length and depth of tissue in KP was greater than CP by 0.06 mm (p=0.810) and 0.14 mm (p=0.634) respectively. There was an exact agreement with final surgical specimen in 42% of cases in both forceps. Agreement within 1 degree was found in 25% of cases with KP and in 17% of cases with CP. Both the forceps equally missed microinvasive lesions but KP was inferior to CP for invasive cancer. Conclusion: KP is almost at par with CP for diagnosing preinvasive cervical lesions and is a useful adjunct to the existing armamentarium of biopsy forceps.
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Srivastava, Astha, Bindiya Gupta, Vikas Lakha und Shilpa Singh. „Study on cervical cancer screening amongst nurses“. In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685284.

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Objective: To study the knowledge, attitude and practice of nurses at tertiary centre regarding cervical cancer screening. Material and Methods: Validated questionnaire was circulated amongst staff nurses at tertiary care centre after taking informed consent. Results and Discussion: Cancer of cervix is the most common genital tract malignancy in female and it is ranked second to breast cancer. It has a positive association with HPV infection. Cervical cancer incidence and mortality have declined substantially following introduction of screening programmes. This present study investigated the knowledge, attitude and practice of nurses at GTB Hospital towards cervical cancer risk factors, sign & symptoms and screening as they are important health professionals. In our study, the results showed that 99% of respondents were aware of Pap smear as screening programme and about 60-70% were aware of HPV as positive organism, but most of them never had a Pap smear done before. Majority of them did not know VIA, VILI and colposcopy as screening techniques. Conclusion: It may thus be recommended that institutions should periodically organize seminars and training for health personnel especially the nurses which form a group of professionals that should give health education to women about cervical cancer.
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Wang, Xiaoxia, Ping Li, Yongzhao DU, Yuchun Lv und Yinglu Chen. „Detection and Inpainting of Specular Reflection in Colposcopic Images with Exemplar-based Method“. In 2019 IEEE 13th International Conference on Anti-counterfeiting, Security, and Identification (ASID). IEEE, 2019. http://dx.doi.org/10.1109/icasid.2019.8925202.

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