Auswahl der wissenschaftlichen Literatur zum Thema „Clinical High-Risk State for Psychosis (CHR-P)“

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Zeitschriftenartikel zum Thema "Clinical High-Risk State for Psychosis (CHR-P)"

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Ruas Resende, M. B., F. Agostinho, R. Nogueira, D. Cotovio, F. A. Silva, and R. Lousada. "Ultra-High-Risk that do not transition to psychosis. What happens?" European Psychiatry 67, S1 (2024): S737. http://dx.doi.org/10.1192/j.eurpsy.2024.1533.

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IntroductionSpeaking prospectively we use the concept of “at risk mental state” (ARMS) to describe the state in which a person has a heightened risk of developing a psychotic disorder. Young people who are experiencing ARMS can be more precisely defined as being at ultra-high-risk of psychosis using a specific set of criteria known as the UHR criteria.ObjectivesTo clarify the concept of ultra-high-risk individuals and to characterize the clinical and functional characteristics and general psychopathology of those individuals that do not transition to psychosis during the follow-up period.Metho
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Richter, Anja, Evangelos Vassos, Matthew J. Kempton, et al. "S175. CLINICAL OUTCOMES IN PEOPLE AT HIGH RISK FOR PSYCHOSIS RELATED TO INTERACTIONS BETWEEN POLYGENIC RISK SCORES AND CHILDHOOD ADVERSITY." Schizophrenia Bulletin 46, Supplement_1 (2020): S104. http://dx.doi.org/10.1093/schbul/sbaa031.241.

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Abstract Background Genetic vulnerability to psychosis is polygenic, involving multiple genes with small individual effects (Psychiatric Genomics Consortium (PGC), 2014). The risk of psychosis is also related to environmental factors, such as childhood trauma (Lardinois et al, 2011). Although the onset of psychosis is thought to result from the interaction of genetic and environmental risk factors (Walker & Diforio, 1997), the extent to which the influence of childhood trauma depends on genetic susceptibility remains unclear. We sought to address this issue in a large prospective study of
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Omelchenko, M. "Premorbid of depressive youth at clinical high-risk for psychosis." European Psychiatry 65, S1 (2022): S683. http://dx.doi.org/10.1192/j.eurpsy.2022.1757.

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Introduction Early detection of psychosis is a promising area in preventive psychiatry. The use of early intervention can prevent the first episode psychosis and improve outcomes. Objectives Identification of premorbid features of depressive patients at clinical high risk for psychosis (CHR) comparing with depressive patients without CHR in order to improve early recognition of the psychotic process. Methods 219 young depressive in-patients with CHR criteria for SOPS with attenuated positive and attenuated negative symptoms and 52 young depressive in-patients without CHR were examined. Presenc
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Fusar-Poli, Paolo. "The Clinical High-Risk State for Psychosis (CHR-P), Version II." Schizophrenia Bulletin 43, no. 1 (2017): 44–47. http://dx.doi.org/10.1093/schbul/sbw158.

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Cleusix, Martine, Ines Khadimallah, Elodie Toffel, et al. "S69. CLINICAL HIGH RISK STATE: STRATIFICATION BASED ON CLINICAL PROFILE AND REDOX STATUS." Schizophrenia Bulletin 46, Supplement_1 (2020): S60. http://dx.doi.org/10.1093/schbul/sbaa031.135.

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Abstract Background The Clinical High Risk state (CHR) concept was implemented to promote the early detection of young help-seeking patients with higher risk of psychotic transition. This category is based on specific clinical criteria (EPA, 2015) and require narrow frequency/duration ratings of subclinical positive psychotic symptoms to allow its definition. Prevalence of CHR “category” appears nevertheless rare in help-seeking young people and the rate of psychotic transition of CHR state is lower than predicted by early studies. Therefore, the binary outcome of transition to psychosis propo
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Omelchenko, M. A. "Clinical High Risk Psychosis: Issues of Diagnostics and Therapy." Psychiatry 18, no. 2 (2020): 82–91. http://dx.doi.org/10.30629/2618-6667-2020-18-2-82-91.

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The aim of the review: the analysis of modern Russian and foreign literature dedicated to the problem of determining diagnostic criteria for clinical high risk of psychosis (CHR-P) and outlining the therapeutic approaches based on the pathogenic mechanisms of their development. Material and method: the publications found by searching queries for keywords in Russian and English in the MEDLINE/PubMed and eLIBRARY databases for the time period from 2010 to 2020 were then analyzed. Conclusion: the review presents a modern definition of the CHR-P group, along with a clarification of individual diag
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Debbané, Martin, George Salaminios, Pablo Cascone, and Marco Armando. "Mentalizing the Clinical High-Risk for Psychosis Model: A Staged Intervention Framework." Psychodynamic Psychiatry 52, no. 4 (2024): 512–41. https://doi.org/10.1521/pdps.2024.52.4.512.

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This article seeks to further specify how the mentalization-based approach may inform clinical intervention before the onset of psychosis, that is, during the stage of clinical high-risk for psychosis (CHR-P). We first review the concept of CHR-P, as well as the research evidence of the impact of early intervention. Next, we present evidence for the centrality of mentalizing as a process that may mitigate the risk for psychosis. We then review some of the key contributions in the psychoanalytical and phenomenological traditions concerning the centrality of core self disturbances in psychosis,
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Lepock, Jennifer R., Romina Mizrahi, Michele Korostil, R. Michael Bagby, Elizabeth W. Pang, and Michael Kiang. "Event-Related Potentials in the Clinical High-Risk (CHR) State for Psychosis: A Systematic Review." Clinical EEG and Neuroscience 49, no. 4 (2018): 215–25. http://dx.doi.org/10.1177/1550059418755212.

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There is emerging evidence that identification and treatment of individuals in the prodromal or clinical high-risk (CHR) state for psychosis can reduce the probability that they will develop a psychotic disorder. Event-related brain potentials (ERPs) are a noninvasive neurophysiological technique that holds promise for improving our understanding of neurocognitive processes underlying the CHR state. We aimed to systematically review the current literature on cognitive ERP studies of the CHR population, in order to summarize and synthesize the results, and their implications for our understandi
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Poletti, Michele. "Early Intervention Services for youth at Clinical High-Risk for Psychosis: The Reggio Emilia At-Risk Mental State (ReARMS) experience." RIVISTA SPERIMENTALE DI FRENIATRIA 146, no. 3 (2022): 61–80. http://dx.doi.org/10.3280/rsf2022-003004.

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Between 2012-2017, 300 individuals completed the baseline assessment, 205 of them met criteria for CHR-P or First-Episode Psychosis, and 154 accepted the enrolment in the ReARMS for treatment and follow-up. Empirical contributions based on the ReARMS dataset involved the structure of assessment and intervention, the Italian validation of ad-hoc instruments of assessment, clinical features of enrolled individuals (anhedonia, aberrant salience, suicidality and metacognition) and longitudinal trajectories in terms of outcome and response to treatments. age between adolescence and young adulthood,
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Oliver, Dominic, Giulia Spada, Joaquim Radua, Philip McGuire, and Paolo Fusar-Poli. "M136. PSYCHOSIS POLYRISK SCORE (PPS): IMPROVING DETECTION OF INDIVIDUALS AT-RISK AND PREDICTION OF CLINICAL OUTCOMES." Schizophrenia Bulletin 46, Supplement_1 (2020): S187. http://dx.doi.org/10.1093/schbul/sbaa030.448.

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Abstract Background Primary prevention in Clinical High Risk for psychosis (CHR-P) can ameliorate the course of psychotic disorders. Further advancements of knowledge have been slowed by the standstill of the field, which is mostly attributed to its epidemiological weakness. This underlies the limited identification power for at-risk individuals and the relatively modest ability of CHR-P interviews to rule-in a state of risk for psychosis. One potential avenue for improving identification of individuals at risk for psychosis is a Psychosis Polyrisk Score (PPS) integrating genetic and non-genet
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Dissertationen zum Thema "Clinical High-Risk State for Psychosis (CHR-P)"

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Remy, Irving. "Les fonctions visuelles rétiniennes et corticales dans les troubles du spectre de la schizophrénie et les situations à risque de psychose." Electronic Thesis or Diss., Strasbourg, 2024. http://www.theses.fr/2024STRAJ030.

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Les troubles psychotiques sont caractérisés par d’importantes conséquences fonctionnelles avec des preuves émergentes concernant l’altération des fonctions visuelles de bas niveau. Le lien anatomique et fonctionnel entre la rétine et le cortex visuel a notamment permis d’émettre des hypothèses quant à l’association entre les altérations des deux étages visuels. Nous avons investigué les mesures électrophysiologiques visuelles rétiniennes et corticales dans les troubles du spectre de la schizophrénie et dans les situations à risque de psychose dont l’usage régulier de cannabis et les phases pré
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Buchteile zum Thema "Clinical High-Risk State for Psychosis (CHR-P)"

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Bora, Emre, Mahesh Jayaram, and Christos Pantelis. "Prevention and early intervention in psychotic disorders." In New Oxford Textbook of Psychiatry, edited by John R. Geddes, Nancy C. Andreasen, and Guy M. Goodwin. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198713005.003.0063.

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This chapter considers treatment approaches in early psychosis and the possibility of prevention prior to the development of illness. The chapter first considers the various definitions of the pre-psychotic state, including prodrome, and the concept of clinical high-risk (CHR) groups. The CHR groups, including the ultra-high-risk (UHR) and basic symptoms (BS) groups aim to identify individuals at imminent risk of transitioning to full-blown psychosis. Further, the chapter summarizes the notion of a staging model for psychosis, which incorporates these earliest pre-psychosis stages, and conside
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Newcomer, John W. "Diabetes mellitus and psychotic disease." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.1580.

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In 2006, investigators compiled data from the public mental health systems of eight states in the USA and compared life expectancy for patients with a major mental illness with general population values. Focusing on states with outpatient as well as inpatient data, this study indicated that individuals with a major mental illness have a mean age at death that is 25–30 years earlier than that observed in the general population over the same years in the same states (1). In this study, ‘major mental illness’ included affective disorders such as major depression and bipolar disorder, attention de
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Berichte der Organisationen zum Thema "Clinical High-Risk State for Psychosis (CHR-P)"

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Can we prevent psychosis in high-risk adolescents? ACAMH, 2021. http://dx.doi.org/10.13056/acamh.14671.

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