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Dissertationen zum Thema „Circadian light“

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1

Best, J. "How quickly does light reset the circadian clock." Thesis, University of Cambridge, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596605.

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The first experiment used the male Syrian hamster as the subject, as it has good wheel-running rhythms with consistent and robust activity onsets and also a well defined phase delay and advance region of the phase response curve (PRC). In this study, a double light pulse paradigm was used to examine if the clock could reset within 2 h. The second light pulse administered 2 h after an initial pulse was used to map the effects of the first light pulse on the resetting behaviour to determine whether the clock had reset to primary light pulse before receiving the second one. The results obtained i
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2

Dixon, Laura Evelyn. "Investigation of light inputs into plant circadian clocks." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5266.

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Circadian clocks are biological signalling networks which have a period of ~24 hours under constant environmental conditions. They have been identified in a wide range of organisms, from cyanobacteria to mammals and through the temporal co-ordination of biological processes are believed to increase individual fitness. The mechanisms which generate these self-sustained rhythms, the pathways of entrainment and the target outputs of the clock are all areas of great interest to circadian biologists. The plant circadian clock is believed to comprise of interlocking feedback loops of transcription a
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Bedrosian, Tracy A. "Circadian Disruption by Light at Night: Implications for Mood." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1363097253.

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4

Breda, Carlo. "Temperature and light entrainment of the Drosophila circadian clock." Thesis, University of Leicester, 2010. http://hdl.handle.net/2381/9743.

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Drosophila melanogaster locomotor activity responds to seasonal conditions by modulating the “evening” activity component. During simulated winters of cold temperature and short days an advanced evening locomotor peak occurs with more daytime locomotor activity; on the other hand long photoperiods and warm temperatures give a delay in the evening peak, thereby avoiding a possible desiccation during the hottest times of the day. This pattern of activity is related to a thermosensitive splicing event that occurs in a 3’ intron in the period gene, with a higher level of splicing and earlier accum
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Moore, H. A. "Circadian rhythmicity and light sensitivity of the zebrafish brain." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1469451/.

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Light is important for entraining circadian rhythms, which regulate a wide range of biological processes. Zebrafish have directly light responsive tissues (Whitmore et al 2000) and are thus a useful vertebrate model for circadian rhythmicity and light sensitivity. Recent studies show the pineal regulates locomotor rhythms (Li et al 2012). However, there are many unresolved questions concerning the neurobiological basis of the zebrafish clock, such as whether neuronal pacemakers, which drive rhythms in other tissues, are present throughout the brain. In this study, per3-luc zebrafish confirm th
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6

Flyktman, A. (Antti). "Effects of transcranial light on molecules regulating circadian rhythm." Doctoral thesis, Oulun yliopisto, 2018. http://urn.fi/urn:isbn:9789526219592.

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Abstract Light acts as the most important regulating and entraining factor of the mammalian circadian rhythm. This rhythm has evolved to set phases, in which different physiological and behavioral events occur at the right time of the day to synchronize the organism. The mechanism of light transduction via eyes to the brain and its effects on circadian rhythmicity is well known. Yet, it has also been shown that light is able to penetrate the skull bone directly, but it is still unknown, whether transcranial light is able to affect molecules regulating circadian rhythmicity. Monoamines and espe
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Fonken, Laura K. "PHYSIOLOGICAL CONSEQUENCES OF CIRCADIAN DISRUPTION BY NIGHTTIME LIGHT EXPOSURE." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1365165088.

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8

Grandner, Michael Andrew. "Sleep, mood, and circadian responses to bright green light during sleep." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3259050.

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Thesis (Ph. D.)--University of California, San Diego and San Diego State University, 2007.<br>Title from first page of PDF file (viewed June 11, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 108-123).
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9

Walmsley, Lauren. "Sensory processing in the mouse circadian system." Thesis, University of Manchester, 2016. https://www.research.manchester.ac.uk/portal/en/theses/sensory-processing-in-the-mouse-circadian-system(bd32ea60-48a8-46d4-b5db-dd83d0326d87).html.

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In order to anticipate the predictable changes in the environment associated with the earth’s rotation, most organisms possess intrinsic biological clocks. To be useful, such clocks require a reliable signal of ‘time’ from the external world. In mammals, light provides the principle source of such information; conveyed to the suprachiasmatic nucleus circadian pacemaker (SCN) either directly from the retina or indirectly via other visual structures such as the thalamic intergeniculate leaflet (IGL). Nonetheless, while the basic pathways supplying sensory information to the clock are well unders
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Hanifin, John P. "Circadian, neuroendocrine and neurobehavioral effects of polychromatic light in humans." Thesis, University of Surrey, 2015. http://epubs.surrey.ac.uk/807999/.

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In the last eighteen years there has been the identification of a novel photopigment, melanopsin, and its subsequent localization to human intrinsically photosensitive retinal ganglion cells (ipRGCs). Since melanopsin’s peak sensitivity is in the short wavelength portion of the visible spectrum (from 447 nm to 484 nm), there has been a steady increase in studies investigating the physiological effects of blue light. This thesis examines polychromatic light mixtures of blue light for circadian, neuroendocrine and neurobehavioral effects in humans. White blue-enriched fluorescent lamps were test
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Najjar, Raymond. "Non visual photoreception in humans : circadian consequences of spectral modulations of light." Thesis, Lyon 1, 2012. http://www.theses.fr/2012LYO10110.

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Chez les mammifères dont l’Homme, les rythmes circadiens physiologiques et comportementaux sont régulés par l’horloge centrale, localisée dans les noyaux suprachiasmatiques de l’hypothalamus. Possédant une période endogène proche mais pas exactement de 24 heures, cette horloge est constamment synchronisée à la période terrestre par le cycle lumière-obscurité perçu au niveau de l’oeil. Cette synchronisation entraîne l’expression de rythmes appropriés (hormonaux, veille-sommeil, température corporelle, etc.). Les hypothèses de ma thèse sont : 1- une exposition chronique à un spectre lumineux app
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Peters, Jennifer Lynn. "Astrocytes and the circadian clock: roles for calcium, light, and melatonin." Diss., Texas A&M University, 2003. http://hdl.handle.net/1969.1/3872.

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Melatonin is rhythmically synthesized and released by the pineal gland and, in some species, retina during the night and regulates many physiological and behavioral processes in birds and mammals. Chick diencephalic astrocytes express two melatonin receptor subtypes in vitro, and melatonin plays a role in regulating metabolic activity. We examined the role of glial cells in circadian function and asked if melatonin modulated glial functions within the retina and the brain. Calcium waves were potentiated by physiological concentrations of melatonin. Melatonin increased resting calcium levels an
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Hurley, Elisabeth. "Effects of early light environment on the photic response of the circadian system." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/effects-of-early-light-environment-on-the-photic-response-of-the-circadian-system(6b32d591-5394-4f1e-a422-7458eb740c2c).html.

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Early light environment has been shown to alter locomotor activity behaviour in adult rats and mice when exposed to constant light (LL), constant darkness (DD) or 12:12 hour light-dark cycles (LD). In particular, exposure to LL during lactation results in an increased ability to cope with exposure to LL as adults, implying that the ability to interpret light information is altered depending on early light environment. Therefore, the aim of this project was to explore how early light environment affects the photic response of the circadian system. The retina forms the first component of the pho
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Itzhacki, Jacobo. "Reward effects of light." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ083/document.

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Pour élucider les effets récompensants de la lumière, deux approches expérimentales ont été adoptées. Une étude chez le rongeur diurne Arvicanthis ansorgei indique que le raccourcissement de la longueur du jour avec la diminution de l'intensité lumineuse induit des changements du rythme de l’activité locomotrice, de la quantité de dopamine dans le système de la récompense et sur l'expression du gène Per2 dans le noyau suprachiasmatique. Ces altérations ont été améliorées par l'exposition journalière à des créneaux d’une heure de lumière à la fin du jour. Dans une étude humaine, le bien-être su
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Deacon, Stephen John. "Manipulation of the human circadian system with bright light and melatonin." Thesis, University of Surrey, 1994. http://epubs.surrey.ac.uk/800041/.

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16

Herljevic, Mirela. "Effect of light and melatonin on circadian physiology in the elderly." Thesis, University of Surrey, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441870.

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17

Petrone, L. "Circadian clock and light input system in the sea urchin larva." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1503707/.

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A circadian clock is an endogenous time-keeping mechanism that synchronizes several biological processes with local environment. In metazoans the circadian system is driven by a regulatory network of so called ―clock‖ genes interconnected in transcriptional-translational feedback loops that generate rhythmicity at mRNA and protein level. Sea urchin and its molecular tools can facilitate the comprehension of the evolution of the time-keeping mechanism in bilaterians. For this purpose we identified and analysed the expression of orthologous clock genes in the sea urchin larvae. Genome survey ide
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Cissé, Yasmine-marie Nirina Cisse. "Multigenerational effects of pre-conception circadian disruption by light at night." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1512163356982794.

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19

Evans, Jennifer Anne. "Changing the shape of circadian rhythms with light no brighter than moonlight." Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3258782.

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Thesis (Ph. D.)--University of California, San Diego, 2007.<br>Title from first page of PDF file (viewed June 8, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 169-188).
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Krupa, Susanne. "Is the nap zone controlled by a light-sensitive circadian arousal process?" Thesis, University of Ottawa (Canada), 2003. http://hdl.handle.net/10393/29056.

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This study attempts to identify the mechanism of the so-called afternoon nap zone. More specifically, it investigates a recent proposal that the afternoon nap zone represents the point in time after morning awakening when process-S has increased to a sufficiently high level to facilitate sleep onset, while at the same time an SCN-controlled circadian arousal process has not yet risen high enough to reverse this increased sleepiness. Eight normal male subjects aged 20--30 years, were monitored on two separate occasions under low ambient light (150 lux). Night sleep hours were maintained at 23:0
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De, Caluwe Joelle. "Modeling the plant circadian clock: a study of light, photoperiodism, and growth." Doctoral thesis, Universite Libre de Bruxelles, 2017. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/251373.

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Le travail présenté dans cette thèse consiste en la création et l'étude des propriétés d'un nouveau modèle computationnel de l'horloge circadienne végétale et de certains processus physiologiques qui en dépendent.L'horloge circadienne est un rythme endogène d'une période d'environ 24 heures que possèdent la plupart des êtres vivants. Il est généré au niveau moléculaire par des boucles de rétroaction transcriptionnelles, traductionnelles et/ou post-traductionnelles. L'horloge permet aux organismes de s'a- dapter à leur environnement. L'horloge des plantes se distingue par un nombre important de
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Edelstein, Kim. "The role of the intergeniculate leaflet in the circadian response to light." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0002/NQ39623.pdf.

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23

Flynn-Evans, Erin E. "Light perception, circadian rhythm disorders and breast cancer risk in blind women." Thesis, University of Surrey, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520563.

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24

Amicarelli, Mario Joseph. "THE EFFECTS OF ORAL COCAINE ON THE CIRCADIAN TIMING SYSTEM." Kent State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=kent1406227527.

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25

Leary, Dagmar Hajkova. "CIRCADIAN PROTEOME CHANGES IN PHOTORECEPTOR OUTER SEGMENTS." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1264276011.

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26

Landry, Glenn J. "Differential effects of constant light on circadian clock resetting by photic and nonphotic stimuli in Syrian hamsters /." Burnaby B.C. : Simon Fraser University, 2006. http://ir.lib.sfu.ca/handle/1892/2623.

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27

Busza, Ania. "Molecular and Behavioral Analysis of Drosophila Circadian Photoreception and Circadian Thermoreception: A Dissertation." eScholarship@UMMS, 2007. https://escholarship.umassmed.edu/gsbs_diss/343.

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Circadian clocks are biological timekeepers that help maintain an organism’s behavior and physiological state optimally timed to the Earth’s day/night cycle. To do this, these internal pacemakers must accurately keep track of time. Equally importantly, they must be able to adjust their oscillations in response to external time cues to remain properly synchronized with the environment, and correctly anticipate environmental changes. When the internal clock is offset from its surrounding day/night cycle, clinically relevant disruptions develop, ranging from inconveniences such as jet-lag to more
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Quiles, Caroline Luísa. "Iluminação artificial : efeito do fotoperíodo e do espectro de cor sobre os ritmos biológicos e metabolismo." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/163577.

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Objetivo: Avaliar a influencia da iluminação artificial nos ritmos biológicos e metabolismo por meio de dois experimentos em ratos Wistar. O primeiro avalia mudanças de fotoperíodo que mimetizem a sazonalidade; o segundo, a qualidade da iluminação artificial (espectro de cor) no ciclo claro/escuro (LD). Métodos: Experimento1 - Três grupos de animais: Controle (CL; n=6, ciclo LD de 12/12); grupo que inicia com fotoperíodo longo (LP/SP; n=7; LD 16.5:7.5); grupo que inicia com fotoperíodo curto (SP/LP; n=7; LD 7.5:16.5). Os grupos experimentais passaram por 18 dias no fotoperíodo inicial, 17 dias
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CREMASCOLI, RICCARDO. "CIRCADIAN RHYTHM DYSFUNCTION IN ALZHEIMER’S DISEASE: HOW TO DETERMINE CIRCADIAN PHASE AND THE ROLE OF TAYLORED LIGHT THERAPY ON SLEEP AND COGNITION." Doctoral thesis, Università degli studi di Pavia, 2020. http://hdl.handle.net/11571/1371755.

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In this thesis circadian rhythm alterations in Alzheimer’s disease (AD) are taken into account, in particular concerning the early stage of disease. In the first part of this 3-year work the research was focused on determining the circadian phase in early AD patients using subjective and objective measures: clinical scales, sleep-wake diaries, salivary melatonin determination (DLMO), phase angles between sleep and melatonin onset. To achieved this goal we performed a case-control observational study comparing the circadian phase of early AD patients elderly healthy controls (Hc). The main resu
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Thapan, Kavita. "The spectral sensitivity of light-induced melatonin suppression in humans." Thesis, University of Surrey, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365184.

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31

Vijayakumar, Sarath Ding Jian. "The role of mediators of neuronal plasticity in the circadian regulation of suprachiasmatic nucleus by light." [Greenville, N.C.] : East Carolina University, 2009. http://hdl.handle.net/10342/2215.

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Thesis (Ph.D.)--East Carolina University, 2009.<br>Presented to the faculty of the Department of Physiology. Advisor: Jian Ding. Title from PDF t.p. (viewed June 12, 2010). Includes bibliographical references.
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James, Francine O. "Circadian adaptation to full-time night shift work with bright light intervention regimen." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31243.

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The primary consequence of night shift work is a misalignment of the endogenous circadian pacemaker with the inverted sleep-wake cycle. This study evaluated the efficacy of a judicious schedule of light exposure on circadian adaptation to night work. Fifteen night shift workers (mean age +/-S.E.M.: 41.8 +/- 1.8 years) were studied for 3 weeks in their work environments under one of two experimental conditions. Treatment group participants underwent an intervention including bright light in the workplace, while control group participants were studied in their habitual light environments. The ef
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Adewoye, Adeolu Badi. "Genetic architecture and molecular mechanisms underlying light entrainment of the Drosophila circadian clock." Thesis, University of Leicester, 2011. http://hdl.handle.net/2381/10229.

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Despite significant progress in the understanding of how the circadian clock is entrained by light, the genetic architecture and molecular basis of this process are still largely unknown. This study was undertaken to identify biological pathways underlying light entrainment in Drosophila melanogaster. Complementary approaches that combined quantitative trait loci (QTL) mapping, complementation tests, and genome-wide gene expression profiling were used. One hundred and twenty-three recombinant inbred lines (RIL) were assayed for circadian photosensitivity. Composite interval mapping identified
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Covington, Michael Fulton. "ELF3 and the light resetting mechanism of the circadian clock in Arabidopsis thaliana /." view abstract or download file of text, 2002. http://wwwlib.umi.com/cr/uoregon/fullcit?p3061940.

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Caddas, Andrew. "Blue Light and Adult Sleep Outcomes." Otterbein University Distinction Theses / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=otbndist1620462993096741.

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Hölbling, Markus. "A HUG OF LIGHT." Thesis, KTH, Ljusdesign, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-297945.

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This project is an elaboration of how luminaire design can provide for fundamental human needs. Visual needs in terms of task performance, orientability and visual comfort; emotional needs in terms of soothing feelings of safeness and cosiness; and biological needs in terms of circadian rhythm and resetting of our biological clock in the morning. These needs are tested through three bedroom scenarios named focus, contemplation and dawn, each with their own demands and desires on lighting qualities.  I have submerged into desired lighting qualities and atmosphere in a bedroom context; into how
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Beauchemin, Kathleen Mary. "Nocturnal psychopathology : sleep, dreaming, mood and light-therapy in bipolar disorder /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq22949.pdf.

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38

Mouland, Josh. "The effect of spatially patterned light on the suprachiasmatic nucleus." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/the-effect-of-spatially-patterned-light-on-the-suprachiasmatic-nucleus(de2b1fff-2058-497e-948a-cc3811ffa39d).html.

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The daily variation in background light intensity (irradiance) can entrain the endogenous clock in the suprachiasmatic nucleus (SCN) to the external environment. The only source of this photic information in mammals is the eye, which is primarily a visual organ. It is therefore highly specialised to detect high frequency spatiotemporal modulations. This together with the adaptation which occurs within the retina could be present difficulties when encoding global irradiance. This raises the question of whether spatial patterns, which are present in our everyday viewing, might affect the ability
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Tseng, Yu-Yao. "Systems biology of the Neurospora circadian clock and its response to light and temperature." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/systems-biology-of-the-neurospora-circadian-clock-and-its-response-to-light-and-temperature(4680ee43-3f65-4398-bc79-bac70d463e58).html.

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Circadian clocks are internal timekeepers that aid survival by allowing organisms, from photosynthetic cyanobacteria to humans, to anticipate predictable daily changes in the environment and make appropriate adjustments to their cellular biochemistry and behaviour. Whilst many of the molecular cogs and gears of circadian clocks are known, the complex interactions of clock components in time and space that generate a reliable internal measure of external time are still under investigation. Computational modelling has aided our understanding of the molecular mechanisms of circadian clocks, never
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Zinna, Valentina Maria. "Shedding light on the temporal organisation of tissue physiology." Doctoral thesis, Universitat de Barcelona, 2021. http://hdl.handle.net/10803/674004.

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Circadian rhythms regulate tissue physiology throughout the day in response to environmental cues. The primary entraining cue for the mammalian circadian clock is light, which is perceived by the retina and transmitted to the suprachiasmatic nucleus (SCN) in the hypothalamus. The SCN establishes behavioural rhythms and coordinates neuronal and hormonal rhythmic signals to be sent to the different peripheral tissues, where the tissue-intrinsic circadian clockwork organises tissue physiology according to the time of the day. The transcription factor BMAL1 is the master circadian regulator, wh
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Sassi, Loretta Natasha. "The effect of light applied to the skin on melatonin, circadian phase and sleep /." Title page, contents and abstract only, 1999. http://web4.library.adelaide.edu.au/theses/09AR.PS/09ar.pss252.pdf.

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42

Thind, Raja Mandeep Singh. "BRIEF CONSTANT LIGHT ACCELERATION OF NONPHOTIC CIRCADIAN PHASE SHIFTING AND REENTRAINMENT OF LD CYCLE." Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1270764667.

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43

Hofer, Sabine. "The circadian system of the cockroach Leucophaea maderae role of the neuropeptide orcokinin and light entrainment = (Das circadiane System der Schabe Leucophaea maderae) /." [S.l. : s.n.], 2004. http://archiv.ub.uni-marburg.de/diss/z2004/0634/.

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44

Sayer, Tamsin. "Variation in central serotoninergic 5-HT1B function through the light-dark cycle : effect of chronic antidepressant treatment." Thesis, University of Bath, 1994. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239953.

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45

Dumpala, Sunila. "The role of retinal photoreceptors in the regulation of circadian rhythms and sleep in systemic disease." Thesis, Queensland University of Technology, 2020. https://eprints.qut.edu.au/203959/1/Sunila_Dumpala_Thesis.pdf.

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Retinal photoreceptors provide light signals to regulate the pupil light reflex, circadian photoentrainment and sleep. People with either diabetes or Parkinson's disease experience circadian disruption, but the pathophysiology is not well understood. This thesis demonstrates that in diabetes, dysfunctional outer retinal rod inputs to melanopsin ganglion cells contribute to the sleep disruption. In Parkinson's disease, the dysfunction is at the level of melanopsin ganglion cells, with additional non-selective reductions in retinal contrast gain. These findings identify new retinal pathways cont
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Alejevski, Faredin. "Photoentrainment of the Drosophila circadian clock through visual system." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLS200.

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La rotation de la Terre oblige les organismes vivants à s’adapter aux modifications cycliques de l’environnement, et tout particulièrement aux changements de lumière et de température. Des unicellulaires à l’Homme, la plupart des espèces ont développé des horloges circadiennes, qui leur permettent d’anticiper les transitions jour-nuit. La lumière constitue le signal majeur pour la synchronisation de l’horloge. En cycles jour-nuit, les drosophiles présentent un profil d’activité locomotrice bimodal, avec un premier pic autour de l’aube et le deuxième au crépuscule. Chez cet insecte, la percepti
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Cao, Ruifeng. "Mammalian Target of Rapamycin Signaling and the Suprachiasmatic Circadian Clock." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1290199441.

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Nitschke, Silvia [Verfasser]. "Novel roles for cytokinin in the responses to high light and circadian stress / Silvia Nitschke." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1068810017/34.

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Nakahira, Yoichi. "Circadian Clock-Regulated Transcription of the psbD Light-Responsive Promoter (psbD LRP) in Wheat Chloroplasts." Kyoto University, 1998. http://hdl.handle.net/2433/182388.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(人間・環境学)<br>甲第7534号<br>人博第48号<br>10||158(吉田南総合図書館)<br>新制||人||11(附属図書館)<br>UT51-98-W278<br>京都大学大学院人間・環境学研究科人間・環境学専攻<br>(主査)教授 豊島 喜則, 教授 丸山 圭蔵, 教授 竹安 邦夫, 教授 藤堂 剛<br>学位規則第4条第1項該当
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Tang, Ni. "Circadian and non-visual regulation of light on sleep-wake states in humans and nocturnal rodents." Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10356.

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La lumière influence de nombreuses fonctions comportementales et physiologiques, comme les cycles veille-sommeil, la sécrétion de mélatonine, le réflexe pupillaire et le métabolisme du glucose. En tant que facteur environnemental clé, elle synchronise le système circadien sur un cycle de 24 heures. Les signaux lumineux sont perçus par les cellules ganglionnaires rétiniennes intrinsèquement photosensibles (ipRGCs), distinctes des bâtonnets et cônes responsables de la vision. Ces ipRGCs envoient les informations lumineuses au noyau suprachiasmatique (NSC) de l'hypothalamus, l'horloge circadienne
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