Thematische Bibliographien / Capsules

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Auswahl der wissenschaftlichen Literatur zum Thema „Capsules“

Autor: Grafiati

Veröffentlicht am 4. Juni 2021

Zuletzt aktualisiert am 9. Juni 2025

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Zeitschriftenartikel zum Thema "Capsules"

Abdullah Al_Raheem, Saad Edan, and Ahmed Hawas Abdullah Anees. "Evaluation of Performance and Estimation of Combining Ability in Flax Crop by Using Factorial Mating Design." Tikrit Journal for Agricultural Sciences 24, no. 2 (June 30, 2024): 102–14. http://dx.doi.org/10.25130/tjas.24.2.9.

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A field experiment was carried out at agricultural field in al-Alam the coordinates of (N 43.835672 - E 34.777260) district/Salahuddin Governorate during (2021 - 2022) A.D season to study, with the aim of evaluating the genotypes and positions in a crop using factorial mating and in these eight flax genotypes were used in this study it is (Sakha 1, Sakha 2, Sakha 3, Sakha 5, Sakha 6, Giza 8, Syrian local and Thorshansity72). and the first parents (males) and the remaining three (females) were chosen to obtain (15) hybrids If the selection was made on the basis of the genetic base of the genotypes, planted randomly and at different dates in the field, and the experiment was applied using a RCBD and with three replications, results and statistical analysis showed the superior genotype (Sakha1) for the traits of the number of capsules per plant (65.66) and the number of seeds in the capsule (9.79) seed capsulesˉ¹ and the yield of the individual plant (2.69) gm plantˉ¹ and the total yield (539.37) kg h-1 and superior hybrid (Sakha1×Syrian local), which significantly outperformed the traits of the number of capsules per plant (67.03) plant capsuleˉ¹, the number of seeds in the capsule (9.77) seed capsuleˉ¹ and the individual plant yield (2.64) g plantˉ¹ and the total yield (529.12) kg h-1. The best parents in the effects of general ability is Genotype (Sakha1) for the traits of the number of vegetative branches, number of capsules per plant, number of seeds per capsule, and the superiority of the hybrid (Sakha1 × Syrian local) in the number of capsules per plant, number of seeds in the capsule, number of seeds per capsule, single plant yield and total and hybrid. Thus, it can be recommended to plant the varieties (Sakha1) (Sakha2) and (Sakha5) because their performance is distinguished in most of the traits under study.

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Chidiac, Samir E., and Mouna A. Reda. "Performance Modeling of Spherical Capsules during Mixing of Self-Consolidating Concrete." Materials 16, no. 6 (March 16, 2023): 2379. http://dx.doi.org/10.3390/ma16062379.

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Autonomous healing is a very promising technique in self-healing concrete systems. For capsules to achieve their anticipated performance, they should be able to survive the harsh mixing conditions of concrete, yet rupture upon concrete cracking. At present, there are no standard test methods, either experimental or analytical, for determining the capsule survival rate during concrete mixing. This study investigates the correlation between the capsules’ shell properties, concrete rheological properties, the capsules’ external forces, and capsule survival rate during concrete mixing. Finite element and statistical modeling techniques were employed to evaluate the capsule performance and predict the survival rate of capsules during concrete mixing, with 68% confidence. The results revealed that the capsules’ survivability during concrete mixing is highly influenced by the capsule’s radius-to-thickness ratio, the rheological properties of the fresh concrete, the average-paste-thickness (APT) of the concrete mix, the aggregate content and angularity, and the speed of the mixer. In brief, capsules with a radius-to-thickness ratio between 30 and 45 are likely to survive concrete mixing and yet still rupture upon concrete cracking.

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Gounley, John, and Yan Peng. "Shape Recovery of Elastic Capsules from Shear Flow Induced Deformation." Communications in Computational Physics 16, no. 1 (July 2014): 56–74. http://dx.doi.org/10.4208/cicp.220513.151113a.

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AbstractRed blood cells undergo substantial shape changes in vivo. Modeled as a viscoelastic capsule, their deformation and equilibrium behavior has been extensively studied. We consider how 2D capsules recover their shape, after having been deformed to ‘equilibrium’ behavior by shear flow. The fluid-structure interaction is modeled using the multiple-relaxation time lattice Boltzmann (LBM) and immersed boundary (IBM) methods. Characterizing the capsule’s shape recovery with the Taylor deformation parameter, we find that a single exponential decay model suffices to describe the recovery of a circular capsule. However, for biconcave capsules whose equilibrium behaviors are tank-treading and tumbling, we posit a two-part recovery, modeled with a pair of exponential decay functions. We consider how these two recovery modes depend on the capsule’s shear elasticity, membrane viscosity, and bending stiffness, along with the ratio of the viscosity of the fluid inside the capsule to the ambient fluid viscosity. We find that the initial recovery mode for a tank-treading biconcave capsule is dominated by shear elasticity and membrane viscosity. On the other hand, the latter recovery mode for both tumbling and tank-treading capsules, depends clearly on shear elasticity, bending stiffness, and the viscosity ratio.

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Pervaiz, Fahad, Sana Ali Zahra, Fariah Qaiser, Syeda Komal Fatima, and Rabbia Mazhar Khan. "Characterization and Evaluation of Capsules and Study of QC tests for Capsules." Global Pharmaceutical Sciences Review III, no. I (December 30, 2018): 7–18. http://dx.doi.org/10.31703/gpsr.2018(iii-i).02.

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Using the capsule as a dosage form dates back to the early pharmacy days; from those days, the capsule preparation process is greatly evolved in order to meet the current needs of patients and the pharmaceutical industry. Currently, all pharmaceutical industries are making a dynamic change in the specifications of particular dosage forms such as capsules. It has become more difficult to obtain the higher valued drug product from the dosage form, along with the potential for improved delivery that can improve clinical outcomes. In addition, the capsules have played a significant role in drug development because of the hand filling or the production of semiautomatic capsular formulations, which have fewer requirements, and can be developed easily. The article will discuss different tests like Universal tests and specific tests, particularly for capsules, performed prior to the release of the batch to ensure efficacy and safety.

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Gupta, Shallini, Kanika Khajuria, Niraj Kumar, and Vijay Khajuria. "Evaluation of capsule labelling for its wall contents as gelatin or non gelatin." International Journal of Basic & Clinical Pharmacology 7, no. 7 (June 22, 2018): 1387. http://dx.doi.org/10.18203/2319-2003.ijbcp20182687.

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Background: Capsules are the most commonly used solid drug dosage form and are made up of gelatin or non gelatin. Currently the gelatin based capsules drug formulations are more used. However, current issue of vegetarian and non vegetarian capsules has come up due to recent Indian government initiative to promote vegetarian capsules.Methods: There were 100 capsule dosage forms were examined for the gelatin or HPMC wall contents and nature of medicine contained in capsules, whether ayurvedic or allopathic.Results: Out of 100 capsules studied 55 had gelatin wall base while 25 had HPMC and 20 capsule labels did not mention the nature of capsule wall constituent. Out of 55 gelatin capsules 30 were of allopathic while 25 capsules were of ayurvedic medicines. Among HPMC, 15 were ayurvedic while 10 allopathic. 20 capsules had no mention of its constituent and among these non labelled capsule formulations had 11 from ayurvedic and 9 from allopathic medicines.Conclusions: The current study revealed that gelatin capsules forms bulk in Indian market. Even the gelatin capsules contained ayurvedic medicines while 10% of HPMC capsules contained allopathic medicines. Non labelled capsules formed 20% of total capsules. These findings suggest wider scope for promotion of HPMC based capsules.

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Rump, Adrian, Marie-Luise Kromrey, Eberhard Scheuch, Vincent Jannin, Lara Rehenbrock, Mladen Vassilev Tzvetkov, Werner Weitschies, and Michael Grimm. "In Vivo Evaluation of a Gastro-Resistant HPMC-Based “Next Generation Enteric” Capsule." Pharmaceutics 14, no. 10 (September 21, 2022): 1999. http://dx.doi.org/10.3390/pharmaceutics14101999.

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Many orally dosed APIs are bioavailable only when formulated as an enteric dosage form to protect them from the harsh environment of the stomach. However, an enteric formulation is often accompanied with a higher development effort in the first place and the potential degradation of fragile APIs during the coating process. Ready-to-use enteric hard capsules would be an easily available alternative to test and develop APIs in enteric formulations, while decreasing the time and cost of process development. In this regard, Lonza Capsugel® Next Generation Enteric capsules offer a promising approach as functional capsules. The in vivo performance of these capsules was observed with two independent techniques (MRI and caffeine in saliva) in eight human volunteers. No disintegration or content release in the stomach was observed, even after highly variable individual gastric residence times (range 7.5 to 82.5 min), indicating the reliable enteric properties of these capsules. Seven capsules disintegrated in the distal part of the small intestine; one capsule showed an uncommonly fast intestinal transit (15 min) and disintegrated in the colon. The results for this latter capsule by MRI and caffeine appearance differed dramatically, whereas for all other capsules disintegrating in the small intestine, the results were very comparable, which highlights the necessity for reliable and complementary measurement methods. No correlation could be found between the gastric residence time and disintegration after gastric emptying, which confirms the robust enteric formulation of those capsules.

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Rump, Adrian, Franziska N. Weiss, Louisa Schulz, Marie-Luise Kromrey, Eberhard Scheuch, Mladen V. Tzvetkov, Tyler White, et al. "The Effect of Capsule-in-Capsule Combinations on In Vivo Disintegration in Human Volunteers: A Combined Imaging and Salivary Tracer Study." Pharmaceutics 13, no. 12 (November 25, 2021): 2002. http://dx.doi.org/10.3390/pharmaceutics13122002.

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Controlling the time point and site of the release of active ingredients within the gastrointestinal tract after administration of oral delivery systems is still a challenge. In this study, the effect of the combination of small capsules (size 3) and large capsules (size 00) on the disintegration site and time was investigated using magnetic resonance imaging (MRI) in combination with a salivary tracer technique. As capsule shells, Vcaps® HPMC capsules, Vcaps® Plus HPMC capsules, gelatin and DRcaps® designed release capsules were used. The three HPMC-based capsules (Vcaps®, Vcaps® Plus and DRcaps® capsules) were tested as single capsules; furthermore, seven DUOCAP® capsule-in-capsule combinations were tested in a 10-way crossover open-label study in six healthy volunteers. The capsules contained iron oxide and hibiscus tea powder as tracers for visualization in MRI, and two different caffeine species (natural caffeine and 13C3) to follow caffeine release and absorption as measured by salivary levels. Results showed that the timing and location of disintegration in the gastrointestinal tract can be measured and differed when using different combinations of capsule shells. Increased variability among the six subjects was observed in most of the capsule combinations. The lowest variability in gastrointestinal localization of disintegration was observed for the DUOCAP® capsule-in-capsule configuration using a DRcaps® designed release capsule within a DRcaps® designed release outer capsule. In this combination, the inner DRcaps® designed release capsule always opened reliably after reaching the ileum. Thus, this combination enables targeted delivery to the distal small intestine. Among the single capsules tested, Vcaps® Plus HPMC capsules showed the fastest and most consistent disintegration.

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Grimm, Michael, Adrian Rump, Marie-Luise Kromrey, Felix Morof, Camille Dumont, Vincent Jannin, Mladen Vassilev Tzvetkov, and Werner Weitschies. "In Vivo Evaluation of a Gastro-Resistant Enprotect® Capsule under Postprandial Conditions." Pharmaceutics 15, no. 11 (November 3, 2023): 2576. http://dx.doi.org/10.3390/pharmaceutics15112576.

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Ready-to-fill enteric hard capsule shells are an evolving field of oral drug and nutraceutical products. Lonza Capsugel® Enprotect® capsules were recently proven to provide reliable release in the small intestine after fasted intake, but robustness against postprandial intake needed to be proven. In this study, the capsules were administered to 16 healthy young subjects after intake of a light meal. The Enprotect® capsules were labelled with 5 mg black iron oxide and 25 mg 13C3-caffeine. Magnetic Resonance Imaging was used to identify the localization and visual dispersion of the capsule filling. The salivary appearance of caffeine was considered a second independent and sensitive marker for the initial release. Whereas the fasted gastric residence time of the capsules amounted to 43 ± 32 min, it was increased to 158 ± 36 min after postprandial intake. Therefore, the mean dispersion time according to MRI and the mean caffeine appearance time were increased to 196 ± 37 min and 189 ± 37 min, respectively. But, similar to fasted administration, no capsule disintegration or leakage was observed in the stomach and 38% of the capsules disintegrated in the jejunum and 62% in the ileum. The mean dispersion time after gastric emptying and the mean caffeine appearance time after gastric emptying amounted to 38 ± 21 min and 31 ± 17 min, respectively. Both did not relevantly change compared to the fasted intake. Only the absolute dispersion time and caffeine appearance were prolonged due to the increased gastric residence and no relevant influence of the light meal was observed on the disintegration or release behavior of Enprotect® capsules after gastric emptying. The capsules also showed robust enteric properties after postprandial administration.

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Koolivand, Abdollah, and Panagiotis Dimitrakopoulos. "Motion of an Elastic Capsule in a Trapezoidal Microchannel under Stokes Flow Conditions." Polymers 12, no. 5 (May 17, 2020): 1144. http://dx.doi.org/10.3390/polym12051144.

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Even though the research interest in the last decades has been mainly focused on the capsule dynamics in cylindrical or rectangular ducts, channels with asymmetric cross-sections may also be desirable especially for capsule migration and sorting. Therefore, in the present study we investigate computationally the motion of an elastic spherical capsule in an isosceles trapezoidal microchannel at low and moderate flow rates under the Stokes regime. The steady-state capsule location is quite close to the location where the single-phase velocity of the surrounding fluid is maximized. Owing to the asymmetry of the trapezoidal channel, the capsule’s steady-state shape is asymmetric while its membrane slowly tank-treads. In addition, our investigation reveals that tall trapezoidal channels with low base ratios produce significant off-center migration for large capsules compared to that for smaller capsules for a given channel length. Thus, we propose a microdevice for the sorting of artificial and physiological capsules based on their size, by utilizing tall trapezoidal microchannels with low base ratios. The proposed sorting microdevice can be readily produced via glass fabrication or as a microfluidic device via micromilling, while the required flow conditions do not cause membrane rupture.

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Jann, Klaus, and Barbara Jann. "Capsules of Escherichia coli, expression and biological significance." Canadian Journal of Microbiology 38, no. 7 (July 1, 1992): 705–10. http://dx.doi.org/10.1139/m92-116.

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Escherichia coli may cause intestinal or extraintestinal infections. Generally, extraintestinal E. coli are encapsulated. The capsules are important virulence determinants, which enable the pathogenic bacteria to evade or counteract the unspecific host defense during the early (preimmune) phase of infection. They interfere with the action of complement and phagocytes. This effect is generally transient and overcome by capsule-specific antibodies in the immune phase of the host defense. In some cases, capsules are not or only poorly immunogenic, as a result of structural relationship or identity with host material. Strains with such capsules (e.g., K1 or K5) are very virulent. Bacterial capsules consist of acidic polysaccharides, which are made up from oligosaccharide repeating units. The capsules of E. coli are divided into two groups, which differ in chemistry, biochemistry, and genetic organization. All capsular polysaccharides are chromosomally determined: those of group I close to his and those of group II close to serA. The biosynthesis and surface expression have been extensively studied with representatives of group II capsular polysaccharides. It could be shown that their biosynthesis is directed from a gene block that determines the synthesis of the polysaccharide, its translocation across the cytoplasmic membrane, as well as its surface expression in a coordinate process. The chemical nature of group II capsular polysaccharides, as well as the mechanism(s) of their biosynthesis and expression, is presented. Key words: Escherichia coli, capsular polysaccharides, structure, genetics, biology.

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Dissertationen zum Thema "Capsules"

Hadjialirezaei, Soosan. "Coating of alginate capsules." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bioteknologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-22908.

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Alginate is a popular candidate for encapsulation of cells due to the formation of gels with divalent ions under physiological conditions. Stable alginate gels can be formed by the selection of alginates with a high content of guluronic acid (G) and gelling in a mixture of calcium and barium. These alginate gels have been proposed as immune protective barriers for the transplantation of human pancreatic islets (insulin producing cells) for the treatment of type 1 diabetes where the alginate gel protects the transplant from the host immune system. Microencapsulation can thus provide a way to overcome the need for immunosuppressive drugs. Although showing promising results in animal models, there are potential limitations of the Ca2+/Ba2+-beads concerning growth of host cells on the surface of capsules in primate models. Development of coating strategies for alginate based capsules could thus be beneficial for reducing the attachment of host cells. Alginate microbeads/capsules were formed by electrostatic bead generator producing beads of 400µm. Afterward, the alginate beads were coated by fluoresceinamine labeled alginate that was visualized by confocal laser scanning microscopy (CLSM) and quantified by fluorescent spectroscopy. The binding of coating alginate to alginate-poly-L-lysine (PLL) capsules was also studied.In this project, in the optimalisation of coating of alginate beads some parameters were studies such as concentration of coating alginate, different gelling ions both for core and coating alginate, exposure time for gelling solution for fixation of coating layer and different washing solution.The long-term stability of coating layer of coated alginate beads was determined by measuring the fluorescent intensity of fluorescently labeled of coating alginate during a period of forty nine days. A stability study of alginate-alginate capsules revealed that Ca2+/Ba2+ alginate coated with high-G alginate and washed with saline and used Ca2+ and Ba2+ with ratio 50:1 for fixation of coating layer were more stable coating than other capsules. The alginate beads coated with high-M or epimerized alginate were produced. It shows higher intensity of coating layer in both capsules coated with high-M or epimerized alginate than alginate beads coated with high-G alginate. In continue of the study, the alginate-PLL capsules were coated with high-G, high-M, and epimerized and sulfated alginate. Alginate-PLL capsules coated with high-G, high-M and epimerized alginate shows no detective signal by confocal images and sulfated alginate coating shows some signal of coating. The stability of coating for alginate-PLL-alginate capsules and alginate beads coated with epimerized or high-M alginate revealed that both kind of coating have high-stability over one week screening.Three dimensional images of capsules, in confocal microscope, both epimerized and high-M coating alginates cover whole of capsules. However, in 3D images we have seen some fragment of coating gelling in the surround solution and attached to the capsules which can make disturbance in spectroscopy measurement. 3D images of alginate-PLL capsules coated with sulfated alginate show evenly distribution of coating.

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Haener, Edgar. "Microfluidic segregation of capsules." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/microfluidic-segregation-of-capsules(a7e001f1-536c-475d-83d5-82aaa4098f5b).html.

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This thesis investigates the transport and sorting of capsules (elastic membranes enclosing a liquid core) using viscous flow in complex vessel geometries. Of particular interest is passive sorting by deformability using only the fluid-structure interaction between the capsule, the viscous fluid and the geometry of the vessel. Millimetric alginate-ovalbumin capsules in the regime of negligible fluid inertia are used in this work. In order to characterise the elastic properties of the capsules, a novel numerical finite element model of the compression of a thick-shelled capsule between parallel plates is implemented. The constitutive model of the capsule membranes was determined by comparison to experimental data: a Yeoh constitutive model with the ratio of constants $C_1 = 1$, $C_2 = 0$ and $C_3 = 10$ describes the capsules used. Three geometries are investigated in this work. (i) A T-Junction bifurcation. Capsule deformation in the T-Junction bifurcation is characterised by the maximal length of the capsule $L_{max}$ and depends on the ratio of viscous to elastic forces, the capillary number $Ca$. The maximal length, $L_{max}$, is especially sensitive at distinguishing soft capsules by their deformability. The sensitivity of $L_{max}$ to capsule compliance and the large deformations that can be achieved makes the T-junction a promising geometry in which to measure elastic properties of the capsules. The rate of relaxation of the capsules after the bifurcation is independent of their deformation. (ii) A half-cylinder obstacle in a channel followed by a sudden expansion. We show that the half-cylinder obstacle causes capsule trajectories to vary depending on deformability. Capsules with a factor of three difference in deformability can be separated. A practical feature of the system is its relative insensitivity to the initial lateral position of the capsules in the channel. However, while the results are reproducible across different capsules, the variations in final position amount to 10 \% at fixed parameters. As these experiments were conducted with the same capsule under identical flow conditions, this is likely to represent the best case scenario. (iii) We adapt the pinched flow fractionation (PFF) geometry to the sorting of capsules. We show that the standard PFF device cannot be used to sort capsules. However, a novel mode of operation, termed the ``T-Junction'' mode, shows great promise for the sorting of capsules. The PFF device in the T-Junction mode separates capsules with a factor of 1.5 difference in deformability. This is twice as sensitive as the half-cylinder device, although larger variability was observed in the PFF device.

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O'leary, Brendan M. (Brendan Michael) 1972. "Self-assembling molecular capsules." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/85343.

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Hélaine, Nelson. "Analyseur optofluidique pour capsules cellulaires." Thesis, Bordeaux, 2020. http://www.theses.fr/2020BORD0158.

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Ce travail de thèse consiste en la conception et l’utilisation d’un système d’analyse d’agrégats multicellulaires par mesure de l’atténuation de la lumière. La technologie des capsules cellulaires brevetée au sein de l’équipe d’accueil peut générer plusieurs milliers de sphéroïdes/organoïdes en quelques secondes. L’objectif est ici de caractériser ces échantillons submillimétriques encapsulés dans une coque transparente par une mesure de leur rayon et de leur coefficient d’atténuation, sans recourir à une technique d’imagerie intrinsèquement lente et bas débit. Pour exploiter le fait que la technique de production est à haut débit, nous proposons de développer un analyseur optofluidique inspiré dans son principe de fonctionnement des cytomètres classiques, mais sans marquage fluorescent des échantillons. Nous avons tout d’abord simulé l’interaction d’un faisceau laser gaussien avec une sphère de rayon et coefficient d’atténuation connus, puis développé le module optique de détection. Les mesures expérimentales ont été confrontées aux simulations pour valider notre approche. Ensuite, nous avons conçu un circuit microfluidique capable de convoyer les capsules cellulaires pesantes au travers du faisceau en utilisant une approche par impression 3D. Enfin, notre système optique a été combiné au module fluidique et modifié pour déterminer la vitesse de déplacement de chaque capsule convoyée au moment de son interaction avec le faisceau d’interrogation. Nous apportons la preuve de concept que le caractère haut-débit d’un tel instrument permet d’analyser un très grand nombre d’échantillons (plusieurs milliers) en peu de temps (quelques heures). L’instrument présenté a été utilisé pour déterminer les courbes de croissance de deux lignées cellulaires de lymphocytes tumoraux (tumeurs « liquides »), ainsi que des modifications de coefficient d’atténuation liées à la fixation sur cellules hépatiques tumorales ou à la stimulation chimique de cellules souches adipeuses qui génèrent des chapelets de gouttelettes lipidiques au cours de leur différenciation. La sensibilité de notre instrument laisse envisager son utilisation dans le cadre d’essais précliniques sur des agrégats de cellules tumorales, afin de déterminer la croissance de ces « micro-tumeurs » et donc estimer l’efficacité de traitements de chimiothérapie par exemple. Enfin, un aspect « open source » a été souhaité dans la conception de l’infrastructure électronique et informatique du prototype, ouvrant ce travail à la copie et l’amélioration, notamment par l’ajout d’un module de tri d’échantillons<br>This work consists in the design and use of a micro-device dedicated to the analysis of multicellular aggregates based on the measure of light attenuation. The celllular capsule technology, which was patented by the host team, can generate several thousand spheroids/organoids in a few seconds. Our objective is to characterize these submillimetric samples encapsulated in a transparent shell by measuring their radius and extinction coefficient without resorting to an inherently slow and low throughput imaging technique. To exploit the high throughput capabilities of the technique, we propose to develop a fluorescence-free optofluidic analyzer inspired from classical cytometers. We first simulated the interaction of a Gaussian laser beam with a sphere of known radius and extinction coefficient and developed the optical detection module. Experimental measurements were compared with simulations to validate our approach. Then, we designed a microfluidic device aimed at conveying the heavy cellular capsules through the beam using a 3D printing approach. Finally, our optical system was combined with the fluidic module and modified to determine the displacement speed of each conveyed capsule as it interacts with the laser beam. We provide a proof of concept that the high throughput of such an instrument allows the analysis of a very large number of samples (several thousands) in a short time (a few hours). The instrument was then used to determine the growth curves of two tumor lymphocyte cell lines ("liquid" tumors), as well as the modifications in the extinction coefficients when cancer cells are fixed and when adipose stem cells undergo differentiation into adipocytes that store lipid droplets. The sensitivity of our instrument is compatible with a further use in pre-clinical trials on tumour cell aggregates to estimate the efficacy of chemotherapy treatments for instance. Finally, an "open source" dimension was integrated into the design of the electronic and software parts of the project to promote copying and improvement, e.g through the addition of a sorting module

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Baillot, Marion. "Capsules hybrides à libération provoquée." Thesis, Bordeaux, 2016. http://www.theses.fr/2016BORD0391/document.

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L’encapsulation est une technique employée couramment par le milieu industriel, notamment dans le domaine du médical, de la parfumerie ou de la cosmétique. Afin de répondre aux attentes et de proposer des capsules modulables pour tous types d’applications, des capsules de type coeur-écorce ont été élaborées au cours de cette thèse. Elles sont obtenues à partir d’émulsion dont le coeur huileux est enrobé par une coque de silice, via la minéralisation de l’interface eau-huile. Les émulsions de Pickering, stabilisées par des particules colloïdales, sont particulièrement stables et intéressantes pour cette étude. Le but de cette thèse est de comprendre, dans un premier temps, les mécanismes fondamentaux impliqués dans le processus de fabrication. Cela a permis d’élaborer, par la suite, des matériaux hybrides complexes à différentes échelles, du micrométrique au nanométrique,mais également d’établir les mécanismes de libération par un stimulus externe. Enfin, une encapsulation maîtrisée permet d’allier stabilité au stockage et destruction rapide ou contrôlée à l’utilisation. Ainsi, par diverses méthodes définies dès la formulation de l’émulsion initiale, le contenu huileux des capsules peut être libéré de manière provoquée par une action mécanique ou par l’augmentation de la température (macroscopique ou local par hyperthermie magnétique)<br>Encapsulation is a technique used in the industry, in particular in the field of medical,perfumery or cosmetics. In order to meet the expectations and propose adaptable capsules for all types of applications, core-shell capsules type were developed during this thesis.There were based on emulsions science with an oily core coated by a silica shell,synthetized by sol-gel chemistry at the oil-water interface. Pickering emulsions, which are emulsions stabilized by colloidal particles, are particularly stable and interesting for this study. The aim of this thesis is to understand, at first, the fundamental mechanisms involved in the manufacturing process. This made it possible to develop complex hybrid materials at different scales, from micrometric to nanometric, but also to establish the releasing mechanisms by an external stimulus. Thanks to a controlled encapsulation, it is possible to combine stability (storage) and rapid or controlled destruction when used. Thus, by various method, defined from the formulation of the initial emulsion, the releasing of the oily contentcan be caused by mechanical action or by an temperature increased (macroscopically orlocally by magnetic hyperthermia)

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Ali, Mir Mukkaram Stöver Harald D. H. "Polymer capsules by living radical polymerization /." *McMaster only, 2004.

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Gebre-Mariam, T. "Drug migration in soft gelatin capsules." Thesis, Cardiff University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381225.

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Stasse, Margot. "Encapsulation d'espèces lipophiles actives par émulsion double." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0030/document.

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De nos jours, l’encapsulation est une technique très répandue dans le domaine de la parfumerie. En effet, elle permet une libération contrôlée du parfum et une protection des molécules de parfumerie qui peuvent s’oxyder avec le temps. L’objectif de cette thèse a été de mettre au point un nouveau concept de capsules fondé sur la formulation d’émulsions doubles huile-dans-eau-dans-huile et de polymériser la phase aqueuse intermédiaire. Les phases huiles, intérieure et extérieure, sont respectivement constituées du parfum et d’un solvant de parfumerie. La phase aqueuse est, elle, composée de monomères hydrophiles dont la polymérisation radicalaire permet l’obtention d’une matrice polymère plus ou moins diffusive vis-à-vis du parfum. L’intérêt de ce nouveau principe d’encapsulation est de séparer la polymérisation et les molécules de parfumerie qui peuvent être réactives en polymérisation radicalaire en les localisant dans des compartiments distincts et ainsi éviter toute interaction. Cette stratégie qui combine la Science des Emulsions, des Polymères et des Parfums et la Formulation a permis l’élaboration de capsules robustes possédant des propriétés de libération progressive par diffusion et de libération provoquée par application d'une contrainte mécanique sans altérer l'intégrité des capsules. Elles se comportent alors comme des micro-éponges capables de se déformer et de reprendre leur forme initiale. Dans ce schéma général, les propriétés peuvent être modulées plus finement par le choix et les concentrations des réactifs lors de la synthèse<br>Nowadays, encapsulation is a widespread technology in fragrance applications. Indeed, it allows control of the fragrance release as well as protection of the fragrance molecules with respect to oxidation. The objective of this PhD is the development of a new concept of encapsulation based on the formulation of double oil-in-water-in-oil emulsion and the polymerization of the intermediate aqueous phase. The two, internal and external, oil phases, , are respectively the fragrance and perfume solvent while the aqueous phase is composed of hydrophilic monomers leading to a more or less fragrance-diffusive polymer matrix after their radical polymerization. The main advantage of this encapsulation principle is to locate the polymerization and the possibly reactive fragrance’s molecules in separate compartments. This strategy which combines the Sciences of Emulsion, Polymers and Fragrance but also the Formulation allows obtaining robust capsules exhibiting both diffusive properties and a triggered release under a mechanical stress. These capsules behaves as micrometric sponges that can deform and restore their initial state.. In this general scheme, the capsules' properties can be tuned by an appropriate choice of the polymerization reactants and their concentrations

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Peña, Castellanos Brisa Marisol. "Preparation and characterization of psf/vanillin capsules." Doctoral thesis, Universitat Rovira i Virgili, 2012. http://hdl.handle.net/10803/84027.

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La industria de detergentes y suavizantes de ropas ha ido incorporado en sus procesos la tecnología de microencapsulación de perfumes. Esta tecnología permite proteger los compuestos volátiles antes, durante y después de los procesos industriales; además, también protege las fragancias durante el ciclo de lavado; asimismo, ofrece una liberación prolongada del perfume durante el secado y almacenamiento de la ropa, haciendo que la fragancia se perciba por más tiempo. Sin embargo, algunas de las cápsulas industriales presentan una serie de desventajas tales como una baja estabilidad del material de la cápsula, una baja capacidad de encapsulación y además con el método industrial de encapsulación que actualmente utilizan es extremadamente complicado encapsular compuestos polares. Con el propósito de resolver estos problemas, se ha propuesto el uso de cápsulas de polisulfona (PSf) con contenido de vainilla y preparadas por la técnica de precipitación por inversión de fases En esta investigación, han sido exitosamente preparadas y caracterizadas cápsulas de PSf/Vanillin. Los resultados muestran que estas cápsulas pueden asegurar una alta capacidad de encapsulación de perfume, una liberación prolongada de la fragancia, una buena estabilidad del material y una protección óptima del perfume. Por todas estas cualidades, las cápsulas de PSf/Vanillin presentan el potencial de ser usadas no solo en detergentes y suavizantes de ropas, sino que también en otros productos textiles.<br>Textile detergent and softener industries have been incorporating in their processes the perfume microencapsulation technology. This technology allows the protection of the fragrance before and during industrial processes, as well as in the product storage. Moreover, it protects the perfume during the laundry and it provides a long-lasting fragrance release after the drying and storage of fabrics. However, certain current industrial microcapsules present a number of drawbacks such as low material stability, low perfume encapsulation capacity and, in addition, with the industrial encapsulation method presently used it is extremely complicated to encapsulate polar perfumes. With the aim to solve these problems, polysulfone (PSf) capsules containing vanillin and prepared by phase inversion precipitation technique have been proposed. In this investigation, PSf/Vanillin capsules have been successfully prepared and characterized. Results show that PSf/Vanillin capsules may ensure a high perfume encapsulation capacity, a long lasting fragrance release, a good material stability, and an optimal perfume protection. Because all these qualities, PSf/Vanillin capsules have the potential to be used not only in detergents and softeners but also in other textile products.

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Rokstad, Anne Mari Aukan. "Alginate capsules as bioreactors for cell therapy." Doctoral thesis, Norwegian University of Science and Technology, Department of Cancer Research and Molecular Medicine, 2006. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1535.

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Bücher zum Thema "Capsules"

Advisory Group for Aerospace Research and Development. Fluid Dynamics Panel., ed. Capsule aerothermodynamics =: L'aerothermodynamique des capsules. Neuilly-sur-Seine: Agard, 1997.

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Jann, Klaus, and Barbara Jann, eds. Bacterial Capsules. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74694-9.

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National Institute on Drug Abuse. Press Office, ed. NIDA capsules. Rockville, MD: Press Office of the National Institute of Drug Abuse, 1985.

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Bertrand, Guy. 400 capsules linguistiques =: Quatre cents capsules linguistiques. Outremont, Qué: Lanctôt, 1999.

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Jardine, Dick, and Amy Shell-Gellasch, eds. Mathematical Time Capsules. Washington DC: The Mathematical Association of America, 2009. http://dx.doi.org/10.5948/upo9780883859841.

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Philip, Maffetone, and International College of Applied Kinesiology., eds. The Health capsules book. Shawnee Mission, Kan. (Box 25276 Shawnee Mission 66225): International College of Applied Kinesiology-U.S.A., 1992.

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Šenk, Peter. Capsules: Typology of Other Architecture. New York: Routledge, 2017.: Routledge, 2017. http://dx.doi.org/10.4324/9781315272177.

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Kesseler, Rob. Seeds: Time capsules of life. 2nd ed. Richmond Hill, Ont: Firefly Books, 2009.

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Maffetone, Philip. The health capsules book II. Lawrence, KS (P.O. Box 905, Lawrence) 66044-0905: ICAK, 1994.

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K, Ridgway, ed. Hard capsules: Development and technology. London: Pharmaceutical Press, 1987.

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Buchteile zum Thema "Capsules"

Rogosa, Morrison, Micah I. Krichevsky, and Rita R. Colwell. "Capsules." In Springer Series in Microbiology, 86. New York, NY: Springer New York, 1986. http://dx.doi.org/10.1007/978-1-4612-4986-3_13.

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Yother, Janet. "Capsules." In The Pneumococcus, 30–48. Washington, DC, USA: ASM Press, 2014. http://dx.doi.org/10.1128/9781555816537.ch3.

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Mahato, Ram I., Ajit S. Narang, and Virender Kumar. "Capsules." In Pharmaceutical Dosage Forms and Drug Delivery, 373–88. 4th ed. New York: CRC Press, 2024. http://dx.doi.org/10.1201/9781003389378-24.

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Piacentini, Emma. "Hydrogel Capsules." In Encyclopedia of Membranes, 980–82. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-44324-8_1946.

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Mehlhorn, Heinz. "Buccal Capsules." In Encyclopedia of Parasitology, 376. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_467.

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Mehlhorn, Heinz. "Buccal Capsules." In Encyclopedia of Parasitology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-642-27769-6_467-2.

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Brouwer-van Hulst, D., and C. R. C. Huizinga-Arp. "4 Capsules." In Bereiden in de apotheek, 50–67. Houten: Bohn Stafleu van Loghum, 2008. http://dx.doi.org/10.1007/978-90-313-6286-8_4.

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Piacentini, Emma. "Hydrogel Capsules." In Encyclopedia of Membranes, 1–2. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-40872-4_1946-1.

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Dangles, Olivier. "Time Capsules." In Climate Change on Mountains, 59–100. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-39528-4_3.

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Radovici, Alexandru, and Ioana Culic. "Service Capsules." In Getting Started with Secure Embedded Systems, 417–71. Berkeley, CA: Apress, 2022. http://dx.doi.org/10.1007/978-1-4842-7789-8_10.

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Konferenzberichte zum Thema "Capsules"

Pierson, E., J. Stubbe, and G. Deny. "Stress Corrosion Cracking of Alloys 690, 800 and 600 in Acid Environments Containing Copper Oxides." In CORROSION 1996, 1–13. NACE International, 1996. https://doi.org/10.5006/c1996-96119.

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Abstract Secondary side stress corrosion cracking (SCC) of steam generator (SG) tubes may be due to the formation of an acid environment in crevices, as demonstrated for several Belgian plants. The susceptibility of alloys 600 and 800 in this type of environment, which had been partially evidenced by several laboratory works, has been confirmed by capsule tests performed at Laborelec, whereas the SCC resistance of alloy 690 always appeared excellent1. Capsule tests have been recently conducted at 320 °C with the same heats of tubings in the same acid solutions (cationic resins + magnetite + sodium silicate, with or without lead, and sodium sulfate + iron sulfate, with or without lead oxide) containing CuO and Cu2O. It appeared that the SCC resistance of the three alloys was generally reduced by the addition of copper oxides, at least when the cover gas did not contain hydrogen. The situation was particularly dramatic for the capsules made of alloy 690 tubing: most of them developed deep cracks, sometimes throughwall (the shortest time to failure being less than 50 h) whereas the same solutions without copper oxides had produced no cracking at all in alloy 690 capsules exposed during more than 2000 h. Although the corrosion is reduced in presence of hydrazine or at lower concentration, copper oxides probably contribute significantly to the degradation of the tubes in alloy 600, at least in SG’s forming acid sulfate crevice environments. This is also an issue for the new SG’s, especially for those equipped with tubes in alloy 690 TT, particularly for the top of the tubesheet which is a critical deposit area since the high stresses and strains resulting from the expansion of the tube in the tubesheet lead to a risk of circumferential cracking at the transition.

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Ye, Daoyuan, Juntao Li, and Yiting Shen. "The Convergence of Dynamic Routing Between Capsules." In 2024 IEEE International Conference on Data, Information, Knowledge and Wisdom (DIKW), 1–7. IEEE, 2024. https://doi.org/10.1109/dikw64278.2024.00011.

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Ding, Xinpeng, Nannan Wang, Xinbo Gao, Jie Li, and Xiaoyu Wang. "Group Reconstruction and Max-Pooling Residual Capsule Network." In Twenty-Eighth International Joint Conference on Artificial Intelligence {IJCAI-19}. California: International Joint Conferences on Artificial Intelligence Organization, 2019. http://dx.doi.org/10.24963/ijcai.2019/310.

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In capsule networks, the mapping of low-level capsules to high-level capsules is achieved by a routing-by-agreement algorithm. Since the capsule is made up of collections of neurons and the routing mechanism involves all the capsules instead of simply discarding some of the neurons like Max-Pooling, the capsule network has stronger representation ability than the traditional neural network. However, considering too much low-level capsules' information will cause its corresponding upper layer capsules to be interfered by other irrelevant information or noise capsules. Therefore, the original capsule network does not perform well on complex data structure. What's worse, computational complexity becomes a bottleneck in dealing with large data networks. In order to solve these shortcomings, this paper proposes a group reconstruction and max-pooling residual capsule network (GRMR-CapsNet). We build a block in which all capsules are divided into different groups and perform group reconstruction routing algorithm to obtain the corresponding high-level capsules. Between the lower and higher layers, Capsule Max-Pooling is adopted to prevent overfitting. We conduct experiments on CIFAR-10/100 and SVHN datasets and the results show that our method can perform better against state-of-the-arts.

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Du, Hongliu, and Satish S. Nair. "Design of a Train Separator for Hydraulic Capsule Pipeline Control." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-0544.

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Abstract Design of an important component for reliable functioning of hydraulic capsule pipelines [1–3] is discussed. A method for sizing the separator and predicting the spacing between capsules after the capsule train passes through the separator is developed. The proposed design has been implemented in hardware. Limited experimental results show that the capsules were separated as expected and the observed spacing between capsules matches the calculated values predicted by analytical methods.

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Liu, Henry, Xiang Gao, and Wenwei Xu. "Flow Regimes and Equations for Predicting Capsule Flow Through Pipe." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0752.

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Abstract The motion of cylindrical capsules in pipe can be classified into four regimes. The characteristics of each regime are described and analyzed in this paper. In each of the four regimes, the pressure drop across a capsule or capsule train (comprising a number of capsules with zero spacing or very small spacing between neighboring capsules) can be predicted by using the one-dimensional energy, momentum and continuity equations with proper consideration for the headloss including entrance and exit effects. The effect of eccentric annulus is taken into account. In predicting the capsule velocity, equations are derived by applying the overall force balance to both the capsule train and the annular flow surrounding the capsule train. Comparison with experimental data shows the incipient velocity, the capsule velocity, and the drag coefficient can be determined accurately from the theory.

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Tonelli, Annachiara, David Mosna, and Giuseppe Vignali. "Comparative Life Cycle Assessment of different packaging systems for coffee capsules." In the 4th International Food Operations and Processing Simulation Workshop. CAL-TEK srl, 2018. http://dx.doi.org/10.46354/i3m.2018.foodops.001.

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"The aim of this work is to compare the environmental impact of three different packaging systems for coffee capsules, which can be used in the same coffee machine. A comparative Life Cycle Assessment has been performed considering the following three types of coffee capsules: 1. Compostable coffee capsules packaged into a multichamber PET tray. 2. Capsules made of aluminium and packaged into cardboard boxes. 3. Capsules made of polypropylene with an aluminium top lid, singularly packaged in modified atmosphere into a bag made of multilayer film of aluminium and polypropylene. The functional unit considered is a coffee capsule. To evaluate the environmental impact, the EPD (Environmental Product Declaration) method is used. This work shows that it is possible to reduce the environmental impact of compostable capsules packaged in PET tray by two ways: by using a less polluting starch polymer and by producing biogas instead of compost from the organic waste. With these improvements, the compostable coffee capsule in PET tray results the less damaging packaging system for all categories except than for the ozone layer depletion and the fossil fuels depletion."

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Kazemi, Zahra, and Mohammad Azami. "Overall Mechanical Properties of Self-Healing Composites: Effects of Microcapsules Shape, Volume Concentration, Shell Thickness, and Material Properties." In ASME 2022 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/imece2022-88439.

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Abstract The present work investigates the influence of embedding spherical and spheroidal capsules containing the healing agent within the base polymers to create a self-healing effect on the overall mechanical properties of the entire medium, using numerical and analytical homogenization approaches. The effects of geometrical and mechanical parameters, including capsule shape, the healing agent volume concentration, the capsules shell thickness, and mechanical properties on the overall responses of the self-healing composites are studied. A square-array configuration is assumed for the distribution of the capsules. This idealization enables computing the behavior of such composites computationally via FE analysis and variationally using Hashin-Shtrikman upper bound by taking a unit cell composed of a cube of the matrix with a perfectly bonded capsule at its center. The boundary conditions on the unit cell are applied in a way that the deformation of the unit cell captivates the overall mechanical responses of the entire medium. Our results show a general decrease in the overall properties of the composites, which can be alleviated by increasing the thickness of the capsules shell or using a stiffer shell. Additionally, we show that the geometry of the capsule shell plays a role in reducing the drop in the overall properties of the composite.

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Kalluri, R. Murthy, Sai K. Doddi, and Prosenjit Bagchi. "Binary Interaction of Liquid Capsules in a Shear Flow." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-67670.

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Three-dimensional numerical simulations using front-tracking method are presented on the hydrodynamic interaction between two deformable particles suspended in simple shear flow. Particles are modeled as liquid capsules, that is, liquid drops surrounded by elastic membranes. Small and finite inertia are considered. Two sets of simulations are presented. In the first set, interaction between two identical capsules are considered. In the limit of zero inertia, it has been known from past research that the hydrodynamic interaction between two deformable particles results in an irreversible shift in the trajectories of the particles as one particle rolls over the other. We show that the presence of inertia can significantly alter the capsule trajectories, and the capsules engage in a symmetric spiraling motions. In the second set of simulations, we consider the interaction between two non-identical capsules which differ from each other in terms of capillary number. The interaction between them results in greater lateral separation as compared to that of an identical pair. This result suggests that the shear-induced diffusion mechanism may play an even greater role in mixing in suspension of bidisperse particles. The long-time trajectory of the non-identical capsules at finite Re shows that they move in spirals with different radii while translating along the streamwise direction. The more deformable capsule moves with smaller radius, and vice versa.

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Mirz, Markus, Marie Franke-Jurisch, Simone Herzog, Anke Kaletsch, and Christoph Broeckmann. "A Comparative Study On Different Joining Techniques For PM-HIP Evacuation Tubes." In World Powder Metallurgy 2022 Congress & Exhibition. EPMA, 2022. http://dx.doi.org/10.59499/wp225370176.

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The main purpose of evacuation tubes in powder metallurgically-based (PM) Hot Isostatic Pressing (HIP) lies in the evacuation and outgassing of the capsule. Conventional HIP capsules are made of sheet-metal which exhibits good weldability and therefore, it is easy to join the evacuation tube. With the emerging technologies of Additive Manufacturing (AM) it is now possible to design more complex capsules for HIP. Additionally, wear-resistant materials can be utilized. Yet, these materials are known to be difficult to weld. This study compares three different approaches to bond an AISI 304 evacuation tube to a HIP capsule made by Electron Beam Melting (EBM) from high carbon tool steel AISI A11. Capsules were bonded by TIG welding as well as brazing with conventional and a customized filler material based on thermodynamic calculations. Subsequent consolidation by HIP, microstructural analysis and argon-measurements revealed the feasibility and limits of all three approaches for gas-tight bonds.

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Mirz, M. "Manufacturing of Net-Shape and Wear-Resistant Composite Components via the Combination of Additive Manufacturing and Hot Isostatic Pressing." In Hot Isostatic Pressing. Materials Research Forum LLC, 2023. http://dx.doi.org/10.21741/9781644902837-12.

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Abstract. Additive Manufacturing (AM) is an emerging technology with increasing importance in scientific and industrial applications. It is suitable for the manufacturing of very complex components straight from CAD data. Furthermore, it can complement powder metallurgical (PM) Hot Isostatic Pressing (HIP) when it is used to produce geometrical complex capsules, opposed to the manual fabrication by welding of sheet metal. This combined process route is highly automatable and can even be further enhanced when it is accompanied by numerical simulations in the design process of the near-net-shape capsules. Due to design optimization, there is no need to remove the capsule and it becomes an integral and functional part of the component. When the capsule is produced e.g., from wear-resistant materials, it can form a wear-resistant outer layer. This study comprises the manufacturing of net-shape and wear-resistant HIP capsules from the carbide rich cold working tool steel AISI A11 (X245VCrMo10-5-1) via Powder Bed Fusion – Electron Beam (PBF-EB). The capsules are filled with the tough Q+T steel AISI L6 (56NiCrMoV7) and densified by HIP with an integrated heat treatment. The focus is on the validation of the simulation, microstructural analysis, as well as analysis of the wear-resistance.

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Berichte der Organisationen zum Thema "Capsules"

Li, Zifeng, Yuling Fan, Yunhong Lei, Xiaoqiang Hou, and Caiyun Chang. A protocol for systematic review and network meta-analysis Efficacy and Safety of Kunxian Capsule in Treating Patients with Lupus Nephritis：A network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2021. http://dx.doi.org/10.37766/inplasy2021.12.0005.

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Review question / Objective: To study on the efficacy and safety of Kunxian Capsule in treating patients with lupus nephritis( LN). Condition being studied: The study showed that Kunxian capsule significantly improved immune status and renal function and suppressed IL-10 and TNF in serum of lupus mice- α Of secretion, works better in combination with and reduces hormone dosage. At present, there are few studies in which Kunxian capsules are used in the clinic, and the conclusions of the studies are inconsistent, so this study was conducted in order to comprehensively evaluate the efficacy and safety of Kunxian capsules for the treatment of lupus nephritis.

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Schwarz, R. A. ,. Westinghouse Hanford. Dose rate calculations for strontium fluoride capsules and cesium chloride capsules and for such capsules as overpacked for disposal. Office of Scientific and Technical Information (OSTI), December 1996. http://dx.doi.org/10.2172/330740.

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RITTMANN, P. D. Photon Production Within Storage Capsules. Office of Scientific and Technical Information (OSTI), August 2003. http://dx.doi.org/10.2172/815079.

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Feng, Ningning, Jianbin Guan, Xing Yu, Wenhao Li, Tao Liu, Guozheng Jiang, Kaitan Yang, Yongdong Yang, and He Zhao. Jintiange Capsule May Have a Positive Effect in OVCF Patients with percutaneous vertebral augmentation: A Meta-Analysis of Randomized Trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0038.

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Review question / Objective: We aimed to conduct a meta-analysis of the effects of JTG capsules on patients with OVCF underwent PVA surgery, focusing on clinical outcomes and drug safety. Condition being studied: This meta-analysis aims to systematic evaluation of clinical efficacy and adverse effects of JTG with PVA in the treatment of osteoporotic vertebral compression fracture (OVCF).Our current evidence suggests that JTG capsule may relieve pain in OVCF patients who underwent PVA surgery, improve functional activity, and increase BMD, particularly in patients under the age of 70, as well as increase BGP levels.However, considering the unsatisfactory quality of the included trials, more high-quality trials are needed to prove this issue.

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Bloomster, C. H., D. R. Brown, G. A. Bruno, R. F. Hazelton, P. L. Hendrickson, A. J. Lezberg, G. L. Tingey, and G. L. Wilfert. Potential value of Cs-137 capsules. Office of Scientific and Technical Information (OSTI), April 1985. http://dx.doi.org/10.2172/5714125.

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Alford, C. S. Sputter deposited beryllium fuel capsules for NIF. Office of Scientific and Technical Information (OSTI), February 1998. http://dx.doi.org/10.2172/305832.

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Letts, S., E. Fearon, S. Buckley, J. Klingmann, and B. Cook. Procedures For Making Precision CH Bumps On Capsules. Office of Scientific and Technical Information (OSTI), November 2004. http://dx.doi.org/10.2172/15011419.

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Ruhkamp, J. D. Design development and testing of 60-watt capsules. Office of Scientific and Technical Information (OSTI), September 1995. http://dx.doi.org/10.2172/204242.

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Chen, K., C. Kong, H. Huang, J. Crippen, M. Ratledge, N. Rice, M. Farrell, A. Nikroo, G. Kyrala, and A. Hayes-Sterbenz. Fabrication of Bromine-doped Glow Discharge Polymer Capsules. Office of Scientific and Technical Information (OSTI), July 2017. http://dx.doi.org/10.2172/1466133.

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Bradley, Paul A., Natalia S. Krasheninnikova, Ian L. Tregillis, and Mark J. Schmitt. Preshot Predictions for Defect Induced Mix (DIME) Capsules. Office of Scientific and Technical Information (OSTI), July 2012. http://dx.doi.org/10.2172/1048685.

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