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Pllinta, Dariusz, Ewa Golińska und Aleksander Kulesz. „Evaluation of Measurement Systems According to ISO/TS 16949 and Customer Specific Requirements“. Applied Mechanics and Materials 791 (September 2015): 153–58. http://dx.doi.org/10.4028/www.scientific.net/amm.791.153.
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The article describes technical specification requirements of the international ISO / TS 16949 related to measurement systems assessment. These requirements were confronted with specific customer requirements (CSR) of the VW group included in the VDA 5 manual. On an example of a company from the automotive industry, authors presented the main differences in the two approaches to the same problem and the resulting consequences arising during external audits performed by customers and certification bodies.
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Liu, Can, Shui Cheng Tian und Jie Liu. „Assessment for Safety Capability of Mine Team Leader Based on AHP and GRA“. Applied Mechanics and Materials 522-524 (Februar 2014): 1452–56. http://dx.doi.org/10.4028/www.scientific.net/amm.522-524.1452.
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Assessment index system for safety capability of mine team leaders is established to assess their safety capability accurately, after defining its concept. The system is comprised of two layers, with 5 indexes in the first-layer and 14 indexes in the second-layer. Furthermore, the relative weights of indexes are determined by analytic hierarchy process (AHP). The grey relational assessment model for safety capability of mine team leader is constructed based on the indexes system. The safety capability of 4 mine team leaders are assessed by the model, according to the sequences in their safety capabilities. Assessment for safety capability based on AHP and GRA could be a tool for evaluation and decision-making in mining enterprises.
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Harits, Abdurrahman, Gilang Muhamad Noer und Aris Puji Widodo. „Capability Level Measurement Using COBIT 5 Framework (Case Study: PT. Jasa Cendekia Indonesia)“. Journal of Information Systems and Informatics 3, Nr. 2 (25.06.2021): 341–51. http://dx.doi.org/10.33557/journalisi.v3i2.134.
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PT. Jasa Cendekia Indonesia is a company engaged in the field of recruitment, training and consulting in the provision of human resources. Currently PT. Jasa Cendekia Indonesia has more than 500 outsourcing employees, puts hundreds of Indonesians into the job market and serves more than 30 multinational companies, of course companies need systems that are able to manage and carry out company work operations. This research study aims to conduct an assessment of Information Technology Governance at PT. Jasa Cendekia Indonesia which focuses on the DSS01 domain (manage operations) is measured using the Capability Level in the Cobit 5 Framework. The results obtained from this assessment are needed as an evaluation and input for improvements to Information Technology Governance at PT. Jasa Cendekia Indonesia in the future. The level of ability of PT. Jasa Cendekia Indonesia in the DSS01 process is at a value of 2.80 while the expected level of ability is at level 3 (established process). The recommendation to reach level 3 is expected to be implemented to improve the performance of PT. Jasa Cendekia Indonesia according to the DSS01 process.
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Febriani, Anita, und Anita Febriani. „ANALISA DAN PENGEMBANGAN TATA KELOLA TEKNOLOGI INFORMASI (IT GOVERNANCE) MENGGUNAKAN COBIT 5“. Jurnal Ilmu Komputer 6, Nr. 2 (03.02.2018): 97–102. http://dx.doi.org/10.33060/jik/2017/vol6.iss2.68.
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Success in providing information services can provide a positive impact to the organization that is in accordance with the expectations of stakeholders. Therefore, the application of IT governance, especially for academic information systems need to be monitored and evaluated to ensure that the entire mechanism of IT management goes according to plan, objectives and business processes. The evaluation also should not only be done in the early stages of a system implemented, but should also be done regularly. The methodology in this study using the COBIT 5 framework that begins with those identified and mapped to the COBIT 5 processes selected. We then measured against these processes to determine the level of the current process capability and also carried out targeting the expected level of capability. Process capability level gap analysis of current and expected conducted to determine the extent to which improvements should be made to these processes. Recommendations for improvement of these processes is based on the COBIT framework 5. Results of this research is assessment and targeting capability level 5 COBIT 5 process were selected as well as recommendations for improvement of IT services activities.
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Ashari, Bandi. „Information Security Governance and Management Capability Assessment: A Lesson Learned from Directorate General of Taxes“. Jurnal Penelitian Pos dan Informatika 10, Nr. 1 (01.10.2020): 15. http://dx.doi.org/10.17933/jppi.2020.100102.
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The information has an important role in improving the business operation and serving the decision-making process. The emerging of e-commerce and e-government require more frequent data exchanges included sensitive data. This study will focus on looking at the portrait of the Directorate General of Tax (DGT) in planning and building the ability to enforce IT governance, especially those related to information security. In addition, this research can also be used as a DGT basis for continuous improvement. We use the ISGM capability model to combine COBIT 5 and ISO 27001 as an approach to measure the capability of organizations in governing and manage their information security. We found that DGT’s information security governance and management capability at overall is at level well defined. Almost of ISGM building blocks has been established according to tailor-made policy and standard. With this capability level, DGT’s ISGM could contribute to the business as shown in several DGT’s program. But, to get optimal value from ISGM DGT need to improve the capability level, especially related to organizational aspects like alignment with business strategies and resource management.
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Wang, Zhuo, Haowen Yan, Yuhan Huang und Yazhen Li. „Robustness assessment of China's high-speed railway transportation network“. Abstracts of the ICA 1 (15.07.2019): 1–2. http://dx.doi.org/10.5194/ica-abs-1-398-2019.
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<p><strong>Abstract.</strong> The robustness of the high-speed rail transportation network is closely related to the passenger transportation efficiency, and is also a concrete manifestation of the anti-jamming capability of the high-speed railway transportation system. By the end of 2017, the business mileage of Chinese high-speed railway has reached 25,164 km, the number of passengers has reached 175.216 million, accounting for 56.8% of railway passenger traffic; the number of passenger turnover has reached 587.56 billion person-km, accounting for 43.7% of railway passenger traffic turnover.As of 2018 On December 4th, the country operate 4,251 high-speed railway trains every day. At the same time, passenger transportation efficiency of high-speed railways is highly susceptible to sudden events such as natural disasters. Therefore, quantitative assessment of anti-jamming capability of high-speed railway network, and the propose of specific improvements, are of great practical significance to improve passenger transport efficiency, enhance scientific decision-making high-speed rail transport infrastructure investments.</p><p>This paper used the the high-speed train running data on December 4, 2018 to analyze the work.Its high-speed railway network schematic is shown in Figure 1.</p><p>The Scale-free property of networks means that the node degree of networks obeys power-law distribution. It is generally believed that scale-free networks exhibit robustness against random faults and vulnerability to deliberate attacks. In this paper, the regularity of node degree change is expressed by distribution function P(k). As shown in the degree distribution of double logarithmic coordinate system as shown in Figure 2, the network has a great goodness of fit and better obeys power law score.That is to say, the network is a scale-free network.</p><p>In this paper, random attacks and deliberate attack simulations are used to observe the condition of the structure of China's high-speed railway network, and in order to measure the robustness of high-speed rail network. Among them, the formula refers to random delete a node from the network; deliberate attack is to delete nodes according to their importance. Attack strategies for node degree and intermediate centrality are used to determine which nodes are selected for each simulated attack (the lower the importance, the smaller the impact on the network). According to the three attack strategies for the high-speed railway transportation network, experiments are carried out to carry out continuous simulation attacks on the network: in each time, a node in the network and all its connected edges are deleted, the relative average shortest path and average clustering coefficient of the network at this time are counted. And the degree of fragmentation, looping until all nodes in the network are deleted, that is to say, the network is completely invalid. In Fig. 3, Fig. 4 and Fig. 5, the X axis represents the number of attack nodes, and the Y axis represents the current network structure feature metric.</p><p>It can be seen that the intentional attack based on the centrality of node mediation has the most serious damage to the network, that is, in other word, the state of splitting and crashing of the network.. For deliberate attacks, China's high-speed railway transport network is very fragile, and attacking nodes with high intermediary centrality value is the most destructive to China's high-speed railway transport network. Therefore,in order to ensure the normal operation of passenger transport we need to focus on ensuring the stability of the sites with the highest intermediary value. This paper ranks the sites according to the value of intermediary centrality. Figure 6 shows the top 10 sites in China's high-speed rail transport network with centrality as intermediaries.</p>
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Ortucu, Serkan, und Omer Faruk Algur. „A Laboratory Assessment of Two Local Strains of the Beauveria bassiana (Bals.) Vuill. against the Tetranychus urticae (Acari: Tetranychidae) and Their Potential as a Mycopesticide“. Journal of Pathogens 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/7628175.
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This study was conducted to assess highly pathogenic Beauveria bassiana isolates to be used in biocontrol and to determine their potentials as mycopesticide. For this purpose, two B. bassiana isolates, which were locally isolated from T. urticae, were chosen. Firstly, three suspensions were investigated at the degree of humidity of 65 ± 5% and 100% RH. Secondly, these strains were selected according to their tendency to mass production, tolerance to UV radiation, and capability of producing spore at the different temperatures. Finally, identification of the selected isolate was performed by using ITS rDNA analysis. Both tested fungal isolates were pathogenic to the T. urticae. Mycelial growths of isolate AT076 at 20°C and 30°C were found to be greater than isolate AT007. It was observed that isolate AT076 had more spore production with 1.61 × 107 spore/disc at 30°C and 44.33% germination after UV radiation for 15 min. The numbers of spores per 5 mm disk area for isolates AT076 and AT007 were found to be 1.2 × 106 and 1.0 × 106. These results show that isolate AT076 was more virulent and more UV-tolerant and had higher tendency to mass production compared to isolate AT007 against T. urticae. As a result of this study, isolate AT076 can be used in the biocontrol as mycopesticide.
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Khan, Najeebullah, Shamsuddin Shahid, Kamal Ahmed, Tarmizi Ismail, Nadeem Nawaz und Minwoo Son. „Performance Assessment of General Circulation Model in Simulating Daily Precipitation and Temperature Using Multiple Gridded Datasets“. Water 10, Nr. 12 (06.12.2018): 1793. http://dx.doi.org/10.3390/w10121793.
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The performance of general circulation models (GCMs) in a region are generally assessed according to their capability to simulate historical temperature and precipitation of the region. The performance of 31 GCMs of the Coupled Model Intercomparison Project Phase 5 (CMIP5) is evaluated in this study to identify a suitable ensemble for daily maximum, minimum temperature and precipitation for Pakistan using multiple sets of gridded data, namely: Asian Precipitation–Highly-Resolved Observational Data Integration Towards Evaluation (APHRODITE), Berkeley Earth Surface Temperature (BEST), Princeton Global Meteorological Forcing (PGF) and Climate Prediction Centre (CPC) data. An entropy-based robust feature selection approach known as symmetrical uncertainty (SU) is used for the ranking of GCM. It is known from the results of this study that the spatial distribution of best-ranked GCMs varies for different sets of gridded data. The performance of GCMs is also found to vary for both temperatures and precipitation. The Commonwealth Scientific and Industrial Research Organization, Australia (CSIRO)-Mk3-6-0 and Max Planck Institute (MPI)-ESM-LR perform well for temperature while EC-Earth and MIROC5 perform well for precipitation. A trade-off is formulated to select the common GCMs for different climatic variables and gridded data sets, which identify six GCMs, namely: ACCESS1-3, CESM1-BGC, CMCC-CM, HadGEM2-CC, HadGEM2-ES and MIROC5 for the reliable projection of temperature and precipitation of Pakistan.
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Dunai, László, und Balázs Kövesdi. „Damage assessment of the historical Széchenyi Chain Bridge“. Journal of Computational and Applied Mechanics 15, Nr. 2 (2020): 101–14. http://dx.doi.org/10.32973/jcam.2020.007.
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The Széchenyi Chain Bridge is a 170-year-old historical structure located in the downtown of Budapest. The superstructure of the bridge was reconstructed several times in its history and currently the renewal process of the bridge is under consideration. According to the current plans main girders, chain elements and cross-girders will remain the old structure and the deck system will be replaced by a new orthotropic steel deck. The Budapest University of Technology and Economics, Department of Structural Engineering was involved in the design process and in the assessment of the remaining elements’ condition within the last 5 years. During the project authors were faced with numerous specific important and challenging structural problems, modelling specialties, advanced design methods and research interest. The main part of these unusual characteristics come from the layout of the historical structure, long time traffic and corrosion problems. One of the most important questions during the structural analysis is the condition and rotational capacity of the pins between the chain elements. The chain system is more than 100 years old and the rotational capacity of the pins is questionable due to corrosion and friction. This phenomenon significantly influences the static behaviour of the chain elements and the whole suspending system. The current paper presents the numerical and on-site experimental program on the investigation of the rotational capacity of the pins. A second important question was related to the condition of current deck system. Significant corrosion damage was observed on the steel stringers which might cause damage or local collapse of the bridge deck under public transportation loads. Advanced numerical model using probabilistic analysis (FORM) and measurement based corrosion models are applied to make a risk assessment of the deck system's capability to maintain and keep the current traffic on the bridge before the deck will be replaced. Via this bridge inspection and investigation project the authors would like to demonstrate the application of advanced numerical modelling based design techniques and the industrial application of research models for lifetime assessment and risk analysis of historical structures.
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Specht. „Method of Evaluating the Positioning System Capability for Complying with the Minimum Accuracy Requirements for the International Hydrographic Organization Orders“. Sensors 19, Nr. 18 (06.09.2019): 3860. http://dx.doi.org/10.3390/s19183860.
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According to the IHO (International Hydrographic Organization) S-44 standard, hydrographic surveys can be carried out in four categories, the so-called orders—special, 1a, 1b, and 2—for which minimum accuracy requirements for the applied positioning system have been set out. These amount to, respectively: 2 m, 5 m, 5 m, and 20 m at a confidence level of 0.95. It is widely assumed that GNSS (Global Navigation Satellite System) network solutions with an accuracy of 2–5 cm (p = 0.95) and maritime DGPS (Differential Global Positioning System) systems with an error of 1–2 m (p = 0.95) are currently the two main positioning methods in hydrography. Other positioning systems whose positioning accuracy increases from year to year (and which may serve as alternative solutions) have been omitted. The article proposes a method that enables an assessment of any given navigation positioning system in terms of its compliance (or non-compliance) with the minimum accuracy requirements specified for hydrographic surveys. The method concerned clearly assesses whether a particular positioning system meets the accuracy requirements set out for a particular IHO order. The model was verified, taking into account both past and present research results (stationary and dynamic) derived from tests on the following systems: DGPS, EGNOS (European Geostationary Navigation Overlay Service), and multi-GNSS receivers (GPS/GLONASS/BDS/Galileo). The study confirmed that the DGPS system meets the requirements for all IHO orders and proved that the EGNOS system can currently be applied in measurements in the orders 1a, 1b, and 2. On the other hand, multi-GNSS receivers meet the requirements for order 2, while some of them meet the requirements for orders 1a and 1b as well.
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Aritonang, Christina. „Case Report: Low Vision Management in A 5-Years-Old Due to Retinopathy of Prematurity for Life Quality Improvement“. Folia Medica Indonesiana 56, Nr. 4 (25.11.2020): 314. http://dx.doi.org/10.20473/fmi.v56i4.23418.
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Management of low vision in pediatric patients with greater result can affect their quality of life than in adult low vision patients. Retinopathy of prematurity is the main cause of blindness in children. A case study highlights the tertiary prevention (low vision examination and management) in a 5 year old boy with ROP related blindness to optimize his remaining visual capacity by using optical and non-optical aids that support daily activity and educational learning. A 5-year-old boy with ROP related blindness visited to the low vision clinic after receiving the several treatments for ROP before. His visual acuities were light perception in the right eye and hand movement in the left eye using his current spectacle correction. He had anti VEGF bevacizumab intravitreal injection, vitrectomy and complicated cataract extraction history on the left eye. He was difficult to learn and read numbers and alphabets caused by visual impairment. Upon evaluation by assessment low vision method, his distance visual acuity in the left eye was improved significantly up to 3/40 on LEA Acuity chart with +14.00D. His near vision became 10 M at 30 cm of reading distance (without near correction) and 4 M at 13 cm improved with +3.00 D by spectacle. The non-optical aid devices as reading task were also suggested to improve continuous reading text without difficulty. ROP blindness can be preventable if appropriate, adequate and accessible screening programmes are available. Unfortunately, even with the current screening guidelines and recommended treatment of ROP, many babies suffer from blindness by this disease each year. Low vision assessment and management in pediatric patient with visual impairment according to children need can optimize the recent visual capability of low vision patient and give selfcare daily activity and educational learning.
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Hamid, MA, M. Nurtanto und M. Fawaid. „The Analysis of Learning Implementation Plan in Vocational Subjects Based on 2013 Curriculum“. Innovation of Vocational Technology Education 14, Nr. 1 (27.04.2018): 17. http://dx.doi.org/10.17509/invotec.v14i1.11042.
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The qualified teacher is teacher who has the standards of educator that has capability of their materials according to the standard of the contents and carry out the learning process according to the standard of the process. Learning Implementation Plan (LIP) is the administration prepared teachers before carrying out the learning process. This research aims to know the quality of the LIP who made by teachers. This research is a descriptive qualitative. The data were collected through questionnaire, document’s noting, and interviews method. The research subjects are vocational teachers in SMK Negeri 1 Cilegon. The results of this research shows that (1) the completeness of the components 63.63; (2) conformity between components 85.7; (3) feasibility of competence 100; (4) feasibility of the indicators and the achievement of basic competencies 100; (5) feasibility of the learning objectives 80; (6) formulate learning objectives 75; (7) choosing and organizing the learning material 80; (8) feasibility of the learning activities 84.6; (9) selection of learning methods 100; (10) selection of media, tools and learning resources 85.71; and (11) the feasibility assessment 85.7, so that the average was 85.5 with good qualifications. The LIP is structured properly can increase the effectiveness of learning in the classroom and improve the quality of teaching and graduates are in accordance with the needs of the ASEAN Economic Community.
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Viespoli, Luigi Mario, Francesco Mutignani, Gabor Gulyas, Heikki Remes und Filippo Berto. „Local strain energy based fatigue assessment of cruciform welded joints: experimental data analysis and influence of hot-dip galvanization“. MATEC Web of Conferences 188 (2018): 02013. http://dx.doi.org/10.1051/matecconf/201818802013.
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Performing the fatigue assessment of a welded joint using the Notch Stress Intensity Factors [1] presents two major challenges. The first is the necessity of a precise reconstruction of the stress field around the notch tip, thus needing an extremely refined discretization with an evident computational cost. The other, is that the dimensions of the N-SIFs and so their critical values, vary accordingly to the William’s solution [2] depending on the notch-opening angle. Consequence of this is that the mechanical properties necessary for the assessment vary as a function of the geometry treated. The research to overcome this issue has led to the use of the local Strain Energy Density [3]. The power of this parameter, used as a tool to perform fatigue assessment, consists of having a very low mesh refinement sensitivity [4], being the energy computed directly from nodal displacements and stiffness matrix [5], and having constant dimensions, so constant critical value for a given class of materials. In this paper, the local energetic method is applied to the analysis of the results of a series of tests performed on cruciform load carrying and non-load carrying specimens realized by S235 JRG2 structural steel plates. If load carrying, the fillet welded joints are made of S355 J2+N structural steel. The fatigue testing has been performed in atmosphere at room temperature in as welded condition both with and without the corrosion protective zinc layer. Particularly, the interest is focused on the influence of the zinc layer of the fatigue properties of the joint and on the capability of the local energetic approach, confronted with the classic nominal stress approach, to accurately predict the fatigue failure. To conclude, the investigation of the tests executed reveals no significant difference in the fatigue life for the coated samples, compared with the uncoated specimens and the predictions according to the IIW recommendations [6].
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Scudero, Salvatore, Carlo Marcocci und Antonino D’Alessandro. „Insights on the Italian Seismic Network from location uncertainties“. Journal of Seismology 25, Nr. 4 (05.06.2021): 1061–76. http://dx.doi.org/10.1007/s10950-021-10011-6.
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AbstractProbabilistic earthquake locations provide confidence intervals for the hypocentre solutions such as errors encountered in the position, the origin time, and in magnitude. If the relationship of the parameters relative to the local arrangement of the seismic network is considered, such as the node distance, the number of stations, the seismic gap, and the quality of phase readings), the uncertainties can then provide insights on the location capability of the network. In this paper, we collect the earthquake data recorded from the Italian Seismic Network for a time span of 5 years. The data pertain to three different catalogues according to the progressive refinement phases of the location procedure: automatic location, revised location, and published location. By means of spatial analysis, we assess the distribution of the location-related and network-related estimators across the study area. These estimators are subsequently combined to assess the existence of spatial correlations at a local scale. The results indicate that the Italian network is generally able to provide robust locations at the national scale and for smaller earthquakes, and the elongated shape of Italy (and of its network) does not cause systematic bias in the locations. However, we highlight the existence of subregions in which the performance of the network is weaker. At present, a unique 2D, 3-layer velocity model is used for the earthquake location procedure, and this could represent the main limitation for the improvement of the locations. Therefore, the assessment of locally optimized velocity models is the priority for the homogenization and the improvement of the Italian Seismic Network performance.
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Cianfoni, Alessandro, Daniela Distefano, Pietro Scarone, Gianfranco A. Pesce, Vittoria Espeli, Luigi La Barbera, Tomaso Villa, Michael Reinert, Giuseppe Bonaldi und Joshua A. Hirsch. „Stent screw–assisted internal fixation (SAIF): clinical report of a novel approach to stabilizing and internally fixating vertebrae destroyed by malignancy“. Journal of Neurosurgery: Spine 32, Nr. 4 (April 2020): 507–18. http://dx.doi.org/10.3171/2019.9.spine19711.
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OBJECTIVESevere lytic cancerous lesions of the spine are associated with significant morbidity and treatment challenges. Stabilization and restoration of the axial load capability of the vertebral body (VB) are important to prevent or arrest vertebral collapse. Percutaneous stent screw–assisted internal fixation (SAIF), which anchors a VB stent/cement complex with pedicular screws to the posterior vertebral elements, is a minimally invasive, image-guided, 360° internal fixation technique that can be utilized in this patient cohort. The purpose of this study was to assess the feasibility, safety, and stabilization efficacy of VB reconstruction via the SAIF technique in a cohort of patients with extensive lytic vertebral lesions, who were considered to have an unstable or potentially unstable spine according to the Spinal Instability Neoplastic Score (SINS).METHODSThis study was a retrospective assessment of a prospectively maintained database of a consecutive series of patients with neoplastic extensive extracompartmental osteolysis (Tomita type 4–6) of the VB treated with the SAIF technique. VB reconstruction was assessed on postprocedure plain radiographs and CT by two independent raters. Technical and clinical complications were recorded. Clinical and imaging follow-ups were assessed.RESULTSThirty-five patients with extensive osteolytic metastatic lesions of the VB underwent 36 SAIF procedures. SAIF was performed as a stand-alone procedure in 31/36 cases and was associated with posterior surgical fixation in 5/36 (4/5 with decompressive laminectomy). In 1 case an epidural cement leak required surgical decompression. VB reconstruction was categorized as satisfactory (excellent or good rating) by the two raters in 34/36 cases (94.5%) with an interrater reliability of 94.4% (Cohen’s kappa of 0.8). Follow-up, ranging from 1 to 30 months, was available for 30/36 levels. Long-term follow-up (6–30 months, mean 11.5 months) was available for 16/36 levels. Stability during follow-up was noted in 29/30 cases.CONCLUSIONSSAIF provides 360° nonfusion internal fixation that stabilizes the VB in patients with extensive lytic lesions that would otherwise be challenging to treat.
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Costantino, Andrea, Daniele Noviello, Stefano Mazza, Roberto Berté, Maurizio Vecchi und Flavio Caprioli. „TELEMEDICINE IN IBD: GOOD TRUST FROM OUTPATIENTS DURING THE COVID-19 PANDEMIC IN MILAN (LOMBARDY)“. Inflammatory Bowel Diseases 27, Supplement_1 (01.01.2021): S51. http://dx.doi.org/10.1093/ibd/izaa347.122.
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Abstract Background and Aim During the recent COVID-19 pandemic, telemedicine has enabled many IBD patients worldwide to get access to remote assistance. Some positive reports on the use of telemedicine among patients and healthcare providers have been published1-4, but a patient’s trust perspective is not available yet. The aim of our study was to verify IBD patients’ trust in telemedicine. This study was approved by our local Ethics Committee. Material and Methods At our Gastroenterology Unit in Milan (Italy), 123 video-consultations were delivered to IBD patients with mild or moderate disease, in place of follow-up visits scheduled but not provided during the general lockdown (March-April 2020). Video-calling solutions from Google (Hangouts or Meet) or Microsoft Teams were used according to the patient’s preference. The patients’ trust in telemedicine was assessed through an adapted version of the PAtient Trust Assessment Tool (PATAT) questionnaire.5 The primary endpoint was expressed as a >75% percentage of patients giving a score of at least 4 out of 5 in a Likert Scale for three selected key statements: “I can trust video-consultation”, “I can trust that possible problems with the telemedicine service will be solved properly” and “I feel at ease when working with this website”. The questionnaire was formulated through the EUSurvey platform, widely used for clinical research questionnaires in Europe. Results One-hundred-fifteen (93.4%) video-consultations were performed out of the 123 scheduled. Among the 115 consultations, 100 questionnaires were completed (86.9%). The primary endpoint of trust in the telemedicine service was achieved in 95%, 90% and 84% of patients for the three selected key statements about the trust in the telemedicine service, its capability to solve clinical problems and its ease to use. While clinical outcomes were beyond our intentions, we reported no drugs withdrawal in this cohort nor major events. Conclusion Our results showed that during the COVID-19 pandemic most of our IBD patients accepted to receive a video-consultation in spite of the traditional in-person visit and trusted the video-consultation. References: 1. Bezzio C. et al. Gut 2020;69:1213–1217 2. George L.A., Raymond K. Current Gastroenterology Reports (2020) 22: 12 3. Lees C. W. et al. Gastroenterology 2020; 2020 May 28 4. Allocca M et al. Clin Gastroenterol Hepatol 2020;18:1882–1883 5. Velsen, L. V. et al, H. Int. J. Med. Inform 2017;97:52–58.
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Nichols, S., und B. Bavister. „107 COMPARISON OF PRIMATE SPERM CRYOPRESERVATION PROTOCOLS: POST-THAW SPERM RECOVERY AND HYPERACTIVATION IN CULTURE“. Reproduction, Fertility and Development 18, Nr. 2 (2006): 161. http://dx.doi.org/10.1071/rdv18n2ab107.
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Cryopreservation of spermatozoa provides material for gene banking of genetically valuable males and offers convenience for in vitro fertilization (IVF). In addition, cryobanking of spermatozoa allows less frequent ejaculation collections from males. The present study compared the effectiveness of several published techniques in non-human primates to find the most efficient one for rhesus macaque (Macaca mulatta) semen cryopreservation. The effectiveness of each method was assessed by longevity (post-thaw motility % and duration) and ability to hyperactivate in culture in response to chemical activators (caffeine, dbcAMP) needed for rhesus sperm capacitation (Boatman and Bavister 1984 J. Reprod. Fertil. 71, 357-366). The ability to hyperactivate provides a reasonable assessment of the fertilizing capability of spermatozoa prior to performing IVF; the latter was impractical for this study, given the large number of treatments and endpoints. Spermatozoa were collected via electroejaculation from one male on three occasions to avoid confounding treatments with male effects. Each ejaculate was divided into one of four treatment groups for cryopreservation: Method A (Seier et al. 1993 J. Med. Primatol. 22, 355-359); Method B (Wei et al. 2000); Method C (Sanchez-Partida et al. 2000, Biol. Reprod. 63, 1092-1097); and Method D (Isachenko et al. 2005 Reprod. Biomed. Online 10, 350-354). Protocols were followed according to each published technique. Upon thawing, each sample was split into different incubation conditions: 37�C, 5% CO2 in air or room temperature for 0-24 h. One dose of activators was used according to standard protocol. Statistical analyses of motility rates were performed using 2 � 2 G tests (Sokal and Rohlf 1981 Biometry. New York: W. H. Freeman Co.) to determine significance. Samples cryopreserved using method D did not survive the method (motility = 0) and were not included in the statistical analysis. Methods A-C all demonstrated reasonable post-thaw motility recovery rates (68%, 73%, and 62%, respectively) and underwent capacitation within 30 min of exposure to activators. Sperm motility decreased over time in culture within each treatment at 37�C. However, spermatozoa in Method A were significantly less motile at 4 and 24 h than those in Methods B and C, and Method B spermatozoa were significantly less motile at 24 h than those in Method C. Sperm motility also decreased over time in samples incubated at room temperature, with motility of sperm in Method A motility being significantly less at 24 h than that of sperm in Methods B and C. Method C best preserved motility over time regardless of temperature of incubation upon thawing. Overall, incubation at room temperature preserved motility better than incubation at 37�C. Methods A-C yielded satisfactory post-thaw recovery of progressively motile spermatozoa despite the various differences among their protocols. For long-term use of each sample, however, it would be beneficial to incubate spermatozoa at room temperature after using Method C. This technique appears to be more appropriate for gene banking rhesus semen, and applying this protocol would allow more efficient usage of each semen sample, potentially providing for multiple IVF cases over a 24-h period. This work was supported by NIH Grant RR15395.
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Ramos, E., A. Guillén-Del-Castillo, C. P. Simeón-Aznar, B. Gracia Tello, V. Fonollosa Pla, A. Selva-O’callaghan, L. Sáez-Comet et al. „POS1409 AUTOMATED DETECTION OF SCLERODERMIFORM PATTERNS USING CAPILLARY.IO“. Annals of the Rheumatic Diseases 80, Suppl 1 (19.05.2021): 987.2–988. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4112.
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Background:A nailfold capillaroscopy procedure is a non-invasive, low-cost, and well-established examination that can be used to diagnose several rheumatic autoimmune diseases and support the necessary follow-up of patients. While the clinical implications of the technique are known, a rigorous and in-depth examination of nailfold capillaries remains as one of the major challenges to produce new advances in research and diagnosis, due to practical limitations for analysing the whole nailfold area of each patient. The difference between the different patterns established by Maricq and Cutolo makes it possible to predict the evolution that the patient will present. We introduce Capillary.io, an automatic image reading system able to recognize capillaries in images obtained with any microscope, generate automatic measurements of each capillary and take advantage of this information to report capillary morphology and patterns.Objectives:to determine the ability to detect active and early scerodermiform patterns of Capillary.io.Methods:Forty-nine complete capillaroscopies, reported by expert capillaroscopists according to the different patterns manually (gold standard), were compared with the pattern detection capability of Capillary.io. A scoring system based on the algorithm of the Spanish Capillaroscopy Study Group (GREC) was performed and interpreted by capillary.io for the global interpretation of each of the capillaroscopies analyzed.Results:Overall, 37 of the 49 capillaroscopies reported agreed with the diagnosed pattern (75.51%). Separately, the early pattern presented a concordance of 77.27% and the active pattern of 74.07%. In reference to the findings detected by the Capillary.io system, the mean overall density was 5.01 capillaries/mm in the group with the active pattern compared to 6.46 capillaries/mm in the early pattern. The density of dilations and megacapillaries was 2.81/mm and 1.21/mm in the active pattern group versus 4.69/mm and 0.4/mm in the early pattern group. Global diameters were greater in the active pattern group with an apical mean of 37.3 μm compared to 28.5 μm in the early pattern subgroup.Conclusion:Capillary.io is a simple, easy-to-learn web system for interpreting capillaroscopic images of nail folds. It can be a very useful tool to standardize the interpretation of capillaroscopic images, not only individually for each capillary, but also jointly through the detection of different patterns.References:[1]Chen K, Wang J, Pang J, Cao Y, Xiong Y, Li X, et al. MMDetection: Open MMLab Detection Toolbox and Benchmark. arXiv preprint arXiv:190607155 2019;.[2]Cutolo M, Pizzorni C, Sulli A. Nailfold videocapillaroscopy assessment of microvascular damage in systemic sclerosis - Reply. The Journal of Rheumatology 2000 11;27:2722–2723.[3]Cutolo M, Trombetta AC, Melsens K, Pizzorni C, Sulli A, Ruaro B, et al. Automated assessment of absolute nailfold capillary number on videocapillaroscopic images: Proof of principle and validation in systemic sclerosis. Microcirculation 2018 May;25(4):e12447.[4]Smith V, Vanhaecke A, Herrick AL, Distler O, Guerra MG, Denton CP, et al. Fast track algorithm: How to differentiate a “scleroderma pattern” from a “non-scleroderma pattern”. Autoimmu- nity Reviews 2019 nov;18(11):102394.[5]Tavakol ME, Fatemi A, Karbalaie A, Emrani Z, Erlandsson BE. Nailfold Capillaroscopy in Rheumatic Diseases: Which Parameters Should Be Evaluated? BioMed Research International 2015;2015:1–17.Disclosure of Interests:Eduardo Ramos Shareholder of: Co-founder and shareholder of Capillary.io, Alfredo Guillén-Del-Castillo: None declared, Carmen Pilar Simeón-Aznar: None declared, Borja Gracia Tello Shareholder of: Co-founder and shareholder of Capillary.io, Vicent Fonollosa Pla: None declared, Albert Selva-O’Callaghan: None declared, Luis Sáez-Comet: None declared, Elena Martínez Robles: None declared, Juan José Rios: None declared, Gerard Espinosa: None declared, Jose Antonio Todolí Parra: None declared, Jose Luis Callejas-Rubio: None declared, Norberto Ortego: None declared, Begoña Marí-Alfonso: None declared, Mayka Freire: None declared, Patricia Fanlo: None declared
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„Information System Governance in Higher Education Foundation using COBIT 5 Framework“. International Journal of Recent Technology and Engineering 8, Nr. 6 (30.03.2020): 2798–811. http://dx.doi.org/10.35940/ijrte.f8192.038620.
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This study aims to produce a recommendation for improvement of information system governance that aims to improve its maturity and capability. In this case the process of assessing the level of maturity and capability is carried out at the Higher Education Foundation. Data collection instruments were conducted using direct observation in the company, conducting interviews with selected stakeholders, distributing questionnaires for which respondents had been assigned referring to COBIT 5 framework, as well as conducting a literature study on existing research. The methodology used in this study is the COBIT 5 framework by starting to identify problems and business objectives of the company, with reference to the COBIT process that has been identified and mapped according to analysis needs. Then measure the capability of the ongoing process using a questionnaire whose question provisions have been provided in the Process Assessment Model COBIT 5, thus helping the research process in assessing governance. Then the target level of capability that the company wants is determined. So the gap analysis process is carried out to find out how far the improvement needs to be done by the company to reach the target. The results obtained from this study are an assessment of the level of capability of corporate information system governance and the target level of capability to be achieved based on the chosen COBIT Process. Analysis of the gap between the current governance conditions and the company's targets is made as a recommendation for improving service activities and corporate information system governance.
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Jarsa, Vernando, und Kevin Christianto. „IT Governance Audit with COBIT 5 Framework on DSS Domain“. Kinetik: Game Technology, Information System, Computer Network, Computing, Electronics, and Control, 06.07.2018, 279–86. http://dx.doi.org/10.22219/kinetik.v3i4.665.
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Information technology in organizations plays an important role for the continuity of their current business processes. Almost every organization already has information technology and dependence on their information technology. With the existence of information technology, it can help business process in the organization runs smoothly, and according to desired by every organization. But not infrequently the information technology that has been operating has problems that are very annoying and hinder the business process of the organization. Problems that exist in this company is at the time of maintenance and custom or repair process undertaken by the company. With the existence of the problem, the writer wanted to audit the existing governance in companies that have problems regarding aspects of information technology delivery. The author uses the COBIT 5 framework on the DSS domain (Deliver, Service, and Support) and focuses on the sub domains of DSS01 Manage Operations, DSS02 Manage Service Requests and Incidents, DSS03 Manage Problems, and DSS06 Manage Business Process Controls. The assessment method used is a capability model consisting of five capability levels. Based on the audit of information technology governance conducted by researchers using COBIT 5, then the conclusion of this study is the average capability level of the overall process obtained most of the process has reached level 1 performed process.
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Tseleejav, Batbold, Tumurbaatar Luvsansambuu und Munkh-Erdene Luvsan. „Assessment of organizational management capability and employee’ satisfaction at select maternity hospitals in Ulaanbaatar“. Proceedings of the Mongolian Academy of Sciences, 03.12.2020, 55–64. http://dx.doi.org/10.5564/pmas.v60i4.1506.
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Healthcare organizations are implementing quality management system by forming legal entity, by carrying out administrative structural changes and developing healthcare organization’s structure, set-up, functional standards, clinical guideline, rules and employee´ moral principles. Introduction of accreditation system into healthcare organizations is becoming an accepted standard, however, healthcare paradigm shift outcome is insufficient. In this connection, researchers, citizens and policy makers are speaking out that the quality of and access to healthcare service is getting worse than before. Management capability index presents management assessment by score, assesses outcome of organizational functions and makes it possible to measure management capability. This study was performed at the Amgalan maternity hospital, Urguu maternity hospital and Khuree maternity hospital between July 2019 and September 2019 and cross-sectional study method was used. The study involved 480 employees of above-mentioned hospitals. We used 9 chapter and 90 criteria that were used in more than 30 Mongolian Public (i.e., Governmental) Organizations for capability assessment to determine management capability index of the maternity hospitals. Organization management capabilities, as an organizational goal and task, leadership skill in an organization, appropriate structure and set-up, organization’s incentive and motivation leverage schemes, organization’s relationship and collaboration, organizational behavior and culture, resource utilization, knowledge and innovation, organizational productivity, quality and performance were included in the questionnaire. Organizations capability index was calculated with a score point of 1 to 5 for each question. A total 480 employees, including 220 from the Urguu maternity Hospital, 125 from the Khuree maternity hospital and 135 from the Amgalan maternity hospital were included in this study. When responses to the question of management capability were according to duties and functions, not much difference was observed among the three hospitals, but when the responses were compared with that provided by doctors, nurses, obstetricians and other medical staff, a 1.8 percentage higher point was given by the administrative and service staff. Regression analysis showed strong relation between management capability assessment of doctors, nurses, obstetricians and other employee of the select hospitals (p<0.001 and R=0.89). Organizational management capabilities of Urguu and Khuree Maternity Hospitals, which have not yet introduced quality management system, are different from the Amgalan maternity hospital’s organizational management capability (p=.000). Doctors, obstetricians, nurses and other employee’ assessed organizational management capability by 73.5 percent respectively. There is a positive correlation ship between organizational capability and employee satisfaction. Better and higher management capability of an organization results in higher employee satisfaction.
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Onwe, Mkpuma Rock, G. I. Nwankwor, C. A. Ahiarakwem, Ema Michael Abraham und T. T. Emberga. „Assessment of geospatial capability index for siting waste dump/landfill to control groundwater geopollution using geographic information system (GIS) approach: case study of Abakaliki area and environs, Southeastern Nigeria“. Applied Water Science 10, Nr. 1 (22.11.2019). http://dx.doi.org/10.1007/s13201-019-1087-5.
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AbstractUnderstanding spatial variation of rock and soil is important for capability precision as well as groundwater contamination or geopollution management. In view of waste dump/landfills, geoenvironmental hazards ravaging our land including surface and groundwater contamination, site suitability indexing, spatial distribution and characteristics of underlying rock and soil matter are studied. Rock and soil samples were collected in a systematic grid pattern using simple drill core rig and hand auger. Geostatistical and soil property analyses were conducted on each grid. Groundwater aquifer vulnerability to leachate was studied using depth to water table, recharge (precipitation), aquifer material, topographic slope, impact on vadose zone/vadose zone material and hydraulic conductivity (DRASTIC) and geophysical methods. Human population growth analysis indicates tremendous waste generation. Flash points of waste generation and dumping were noted. Geographical positioning system was used to take record of sampling point coordinates. Using a sufficient dataset, each grid indicative factor is objectively scaled, weighed and assigned a numerical rating according to their relative importance employing site suitability (S) analysis approach in an empirical equation. Results were imported into a geographic information system (GIS) platform to generate thematic maps. The results showed that subsurface rock and soil characteristics are neither spatially nor vertically homogeneously distributed. Thematic maps were generated and further interpolated in the GIS domain to produce a composite waste dump/landfill suitability index map.
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Rask, Mette Trøllund, Pernille Ravn Jakobsen, Jane Clemensen, Marianne Rosendal und Lisbeth Frostholm. „Development of an eHealth programme for self-management of persistent physical symptoms: a qualitative study on user needs in general practice“. BMC Family Practice 22, Nr. 1 (07.02.2021). http://dx.doi.org/10.1186/s12875-021-01380-5.
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Abstract Background Persistent physical symptoms (PPS) are estimated to be present in 17% of patients in general practice. Hence, general practitioners (GPs) play a key role in both the diagnostic assessment and the management of PPS. However, research indicates a need to improve their strategies to support self-help in patients, and eHealth tools may serve as an opportunity. This study aimed to explore patients’ and GPs’ needs related to self-management of PPS. The study was designed to inform the future development of eHealth interventions in this field. Methods This qualitative study was based on 20 semi-structured interviews (6 GPs and 14 patients with PPS). Interviews were audiotaped, transcribed verbatim and analysed through a five-step thematic analysis approach. First, we conducted an inductive analysis to identify and explore emerging subthemes. Second, using a deductive mapping strategy, we categorised the derived subthemes according to the COM-B behaviour change model and its three domains: capability, opportunity and motivation. Results We identified eleven subthemes in the patient interviews and seven subthemes in the GP interviews. Several unmet needs emerged. First, we identified a need to consider PPS early in the illness trajectory by taking a bio-psycho-social approach. Second, both patients and GPs need better skills to manage uncertainty. Third, hope is important for the patients. Fourth, patients need guidance from their GP in how to self-manage their PPS. Conclusions This study provides important insight into key issues and needs related to capability, opportunity and motivation that should be addressed in the design of future eHealth self-management interventions targeting patients with PPS in general practice in order to support and improve care.
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Ciobotaru, V., N. Combes, X. Iriart, E. Marijon, S. Hascoet, A. Nguyen, J. Ternacle et al. „P2436Preliminary data from “LAA-Print French registry”: a large national multi-centric prospective registry evaluating a new preoperative approach based on 3Dprinted simulation in LAAC procedures“. European Heart Journal 40, Supplement_1 (01.10.2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0768.
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Abstract Left atrial appendage closure (LAAC) is an alternative to OAC in patients with contra indication to OAC and AF. But LAAC may be at risk, especially in frail patients. There are no imaging criteria to asses individual procedural risk. Furthermore, procedural factors (double curve catheter alignment) are hard to predict 3D-printing simulation has capability to integrate all anatomical and procedural parameters and has demonstrated improvements in LAAC device sizing in a pilot study Aim To demonstrate efficiency of 3D-printing simulation to predict LAAC procedural risk (failure, long procedure time, pericardial effusion or others serious adverse events (SAES) or inappropriate implantations) Methods Open study: Prospective and Consecutive. Recruiting 150 patients in 16 centres (of 300 patients expected). Start: Jan 18th, 2018. Study Completion: Nov 1st, 2019. ClinicalTrials ID: NCT03330210. 1. Cardiac CT prior to LAAC. 2. Industrial manufacture, laser sintering, of 3D-printed models including the whole LA cavity including interatrial thin septum and vena cava (using material TPU with adequat elasticity: shore 50). 3. LAAC Simulation based on 3Dprinted models using specific sheaths and prosthesis. Prior to LAAC procedure each operator asses a risk score for procedural failure (low/moderate/high) based on real 3D printed LAAC simulation taking into account: trans-septal puncture site/sheath alignment with LAA ostium/device deployment and stability. 4. LAAC procedure TEE guided. 5. CT or TEE control M3 or M6. Procedural outcomes according to risk Sc Low risk (N=63) Moderate risk (N=50) High risk (N=37) p<0.05 vs High risk Failure 1 (1.6%) 1 (2%) 10 (27%) * Recaptures ≥2 4 (6%) 5 (10%) 12 (32%) * Prosthesis ≥2 2 (3%) 1 (2%) 9 (24%) * Inappropriate implantation 0 6 (12%) 7 (19%) * SAES 2 (3%) 6 (12%) 12 (32%) * Pericardial effusion (pericardiocentesis) 2 (3%) 1 (2%) 4 (11%) * Haemorrhage (≥2 points) 0 2 (4%) 5 (13%) * Coronary syndrome 0 0 4 (11%) * Time (intra left atrium) min 21±10 29±16 50±25 * *p<0.05 vs High risk group according to prospective risk score. LAAC simulation on 3D printed model Conclusion 3D printing simulation accurately stratifies the risk of procedure according to LA anatomy. 3D printing may guide the procedure through verification of the transseptal puncture site and/or using a specific catheter shape and device. In case of high risk, a careful assessment of risk/benefice ratio is mandatory Acknowledgement/Funding AG2RFondation and Boston Scientific
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Bond, Virginia, Graeme Hoddinott, Lario Viljoen, Fredrick Ngwenya, Melvin Simuyaba, Bwalya Chiti, Rhoda Ndubani et al. „How ‘place’ matters for addressing the HIV epidemic: evidence from the HPTN 071 (PopART) cluster-randomised controlled trial in Zambia and South Africa“. Trials 22, Nr. 1 (06.04.2021). http://dx.doi.org/10.1186/s13063-021-05198-5.
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Abstract Background In a cluster-randomised trial (CRT) of combination HIV prevention (HPTN 071 (PopART)) in 12 Zambian communities and nine South African communities, carried out from 2012 to 2018, the intervention arm A that offered HIV treatment irrespective of CD4 count did not have a significant impact on population level HIV incidence. Intervention arm B, where HIV incidence was reduced by 30%, followed national guidelines that mid trial (2016) changed from starting HIV treatment according to a CD4 threshold of 500 to universal treatment. Using social science data on the 21 communities, we consider how place (community context) might have influenced the primary outcome result. Methods A social science component documented longitudinally the context of trial communities. Data were collected through rapid qualitative assessment, interviews, group discussions and observations. There were a total of 1547 participants and 1127 observations. Using these data, literature and a series of qualitative analysis steps, we identified key community characteristics of relevance to HIV and triangulated these with HIV community level incidence. Results Two interdependent social factors were relevant to communities’ capability to manage HIV: stability/instability and responsiveness/resistance. Key components of stability were social cohesion; limited social change; a vibrant local economy; better health, education and recreational services; strong institutional presence; established middle-class residents; predictable mobility; and less poverty and crime. Key components of responsiveness were community leadership being open to change, stronger history of HIV initiatives, willingness to take up HIV services, less HIV-related stigma and a supported and enterprising youth population. There was a clear pattern of social factors across arms. Intervention arm A communities were notably more resistant and unstable. Intervention arm B communities were overall more responsive and stable. Conclusions In the specific case of the dissonant primary outcome results from the HPTN 071 (PopART) trial, the chance allocation of less stable, less responsive communities to arm A compared to arm B may explain some of the apparently smaller impact of the intervention in arm A. Stability and responsiveness appear to be two key social factors that may be relevant to secular trends in HIV incidence. We advocate for a systematic approach, using these factors as a framework, to community context in CRTs and monitoring HIV prevention efforts. Trial registration ClinicalTrials.gov NCT01900977. Registered on July 17, 2013.
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Muftikhali, Qilbaaini Effendi, und Tony Dwi Susanto. Jurnal Teknologi Informasi dan Ilmu Komputer 4, Nr. 4 (31.12.2017): 311. http://dx.doi.org/10.25126/jtiik.201744367.
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<p>Abstrak<br />Kemajuan pesat dalam perkembangan teknologi informasi berpengaruh secara global yang dampaknya meluas hampir ke seluruh lini masyarakat. Salah satu bentuk dampak positif dari perkembangan TIK adalah munculya sistem digitalisasi dalam penyelenggaraan pemerintahan yang dikenal sebagai Electronic Government (e- Government). Fenomena e-Government dapat didefinisikan yang mencakup semua penggunaan teknologi informasi oleh instansi pemerintah (seperti WAN, Internet, dan mobile computing) yang memiliki kemampuan untuk mengubah kondisi hubungan dengan warga, bisnis, dan pihak lain. E-Government pada saat ini masih sampai pada tahap pengembangan belum pada tahap evaluasi/penilaian e-government itu sendiri, sedangkan e-Government dapat dilihat mampu memberikan manfaat yang optimal ketika dalam kondisi mature, yaitu kondisi matang atau sempurna. Tujuan dari jurnal adalah membahas model pengembangan model maturity dari E-Government sesuai dengan 5 kategori Capability Maturity Models, the governmental models, the holistic appoarch models, evolutionary e-government model maturity , dan related special purpose model serta kekurangan, kelebihan dari setiap kategorinya.<br />Kata kunci: E-Government,model maturity, model maturity e-Government .</p><p><br />Abstract<br />Rapid advances in information technology are globally influential whose impact extends almost to the entire community. One of the positive impacts of ICT development is the emergence of a digitalization system in government administration known as Electronic Government or e-Government. The phenomenon of e-Government can be defined that includes all the use of information technology by government agencies (such as Wide Area Network, Internet, and mobile computing) that have the ability to change condition relationships with citizens, businesses and other parties. E-Government is still at the stage of development not yet at the stage of evaluation / assessment of e-government itself, while e-Government can be seen able to provide optimal benefits when in mature conditions, ie conditions mature or perfect. The purpose of the journal is to discuss the maturity development model of E-Government according to the five categories of Capability Maturity Models, the governmental models, the holistic appoarch models, the evolutionary e-government maturity model, and related special purpose models and the shortcomings, advantages of each category.<br />Keywords: E-Government,model maturity, model maturity e-Government</p>
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Mahmoudi, Osman, und Mohammad Rauf Amini. „The Reliability and Validity of the Post-Traumatic Stress Disorder Checklist (PCL) in the Earthquake-Stricken Population of Kermanshah, Iran“. International Journal of Health and Life Sciences 6, Nr. 2 (28.07.2020). http://dx.doi.org/10.5812/ijhls.101860.
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Background: The post-traumatic stress disruption checklist (PCL) is a reliable self-assessment measure for post-traumatic stress disorder (PTSD). Recently, the PCL has been updated based on the DSM-5 criteria for PTSD Objectives: The present study aimed to determine the psychometric properties and diagnostic capability of the PCL as a screening tool in an earthquake-stricken population in Kermanshah, Iran. Methods: This cross-sectional study was conducted on 200 injured earthquake victims in Sales and Javanrud counties. The subjects were selected via purposive sampling. The PCL was translated into Kurdish (Surani), and trained interviewers run the translated version for 200 individuals manifesting the symptoms of post-earthquake stress in the earthquake-stricken cities of Javanrud and Sales located in Kermanshah province. After two weeks, 100 participants were randomly selected, and the questionnaire was completed again. Results: The internal consistency of the PCL (α = 85%) was indicative of the validity of the checklist. The Youden’s index with the cutoff point of 23 was considered optimal for the PCL tool. The diagnostic values of sensitivity and specificity were estimated at 0.82 and 0.81, respectively (P < 0.001). In addition, the test-retest results were equal after two weeks (α = 87%), indicating the high reliability of the checklist. Conclusions: According to the results, the PCL is a sensitive and accurate tool for assessing the status of PTSD in disaster victims and accidents and could be used in the screening of PTSD in the health monitoring programs for these victims.
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„Аnalysis of acute and early periods complications of traumatic disease in severe polytrauma“. Journal of V. N. Karazin Kharkiv National University, Series "Medicine", Nr. 38 (2019). http://dx.doi.org/10.26565/2313-6693-2019-38-06.
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Objective of the research is to assess the likelihood of complications in the acute and early periods of Traumatic Disease (TD) and primary condition and reserve capability of hemodynamic and homeostasis in patients with polytrauma. Materials and methods. A retrospective study was carried out on 32 patients suffering from polytrauma. The group of the study included patients with the severity of injury according to the Injury Severity Score (ISS) more than 25 points and on a scale APACHE II 10-25 points at the time of admission. The estimated blood loss was 30-40% of blood volume (BV). The individual assessment of blood loss was calculated by Moor. Results. The study of 20 (62.5%) men, 12 (37.5%) women aged 18 to 60 years old (35.22 ± 12.66) were done. The mechanical ventilation was performed for 30 patients (93.75%), and 2 patients (6.25%) required oxygen therapy 5 lit per min for 3 days. The duration of mechanical ventilation was in 10 patients - up to 1 day, 8 patients - up to 3 days and at 12 - more than 3 days. Among 12 patients, who used AMV more than 3 days, 10 patients were tracheostomy in 3d day and 2 patients were extubated on 4th day. Among the patients examined thirty patients (93.7%) had posthemorrhagic anemia during first day of injury. Infectious complications like purulent tracheobronchitis and pneumonia were observed in 14 (43.75%) patients. The local infectious complications (abscesses, festering wounds) occurred in 5 (15.6%) patients and bedsores in 3 (9,375%) patients. The catheterization of the bladder lead to the development of urinary tract infection in 3 patients (9,3%). Conclusion. The most problematic category of victims includes patients with injuries several anatomical regions. Pneumonia, anemia, urinary tract infection and local infectious complications were considered as the most common complications of acute and early periods TD. The factors that influenced the probability of a high degree of complications were AMV, the thoracic component of the injury, more massive blood loss, long-term catheterization of the bladder.
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Schuurman, A. S., A. Tomer, K. M. Akkerhuis, J. J. Brugts, A. A. Constantinescu, J. Van Ramshorst, V. A. Umans, H. Boersma, D. Rizopoulos und I. Kardys. „P1644Personalized screening intervals for measurement of n-terminal pro-b-type natriuretic peptide improve efficiency of prognostication in patients with chronic heart failure“. European Heart Journal 40, Supplement_1 (01.10.2019). http://dx.doi.org/10.1093/eurheartj/ehz748.0403.
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Abstract Background Predefined screening intervals and target levels do not account for variations in temporal patterns of biomarkers between individuals, which may hamper their potential use for therapy guidance. Conversely, a personalized screening approach with screening intervals and target levels based on the evolution of biomarkers in individual patients may further improve risk assessment and therapy guidance. Purpose We hypothesize that personalized screening intervals for N-terminal pro-B-type natriuretic peptide (NT-proBNP) measurements in patients with chronic heart failure (CHF) maximize information gain on the individual patient's disease progression, while minimizing the number of necessary measurements. We aim to compare such personalized scheduling of NT-proBNP measurements to a predefined fixed scheduling approach. Methods In 263 CHF patients from the Bio-SHiFT study, NT-proBNP was measured trimonthly according to a prespecified, fixed schedule [median: 9 (IQR: 5–10) measurements per patient].The primary composite endpoint (PE) comprised cardiac death, cardiac transplantation, left ventricular assist device implantation or heart failure hospitalization, and occurred in 70 patients (26.6%). Using joint models for time-to-event and longitudinal data, we modelled the association between repeated NT-proBNP measurements and the PE. Using the fitted joint model, for each patient at each follow-up visit, we determined the optimal time point of the next NT-proBNP measurement based on the patient's individual risk profile and the maximum information gain on the patient's prognosis as assessed by the Kullback-Leibler divergence. Personalized scheduling was compared to fixed (trimonthly) scheduling by means of a realistic simulation study, based on a replica of the study population included in the Bio-SHiFT study. In this simulation study, we stopped monitoring NT-proBNP to potentially enable appropriate timely intervention if the cumulative risk of PE exceeded an arbitrary risk threshold of 7.5% within 3-months. We compared personalized scheduling with fixed scheduling in terms of capability of identification of high-risk intervals (whether timely intervention was enabled before occurrence of PE), number of measurements needed, and costs. Results Compared to fixed scheduling, personalized scheduling saved on average 2 measurements [personalized; median: 7 (IQR: 7–8) vs. fixed; 9 (IQR: 8–10) measurements], while the start of the time-window identified for therapeutic intervention to avoid the occurrence of PE was similar in both approaches [personalized; median: 6.6 (IQR: 4.5–11.3) vs. fixed; 6.3 (IQR: 4.2–10.3) months before occurrence of PE]. Costs saved were €165 per patient per year. Figure 1 Conclusion Personalized scheduling of NT-proBNP measurements in CHF patients shows similar prognostic performance as fixed scheduling, but requires fewer NT-proBNP measurements. This may improve efficiency of natriuretic guided therapy, if the latter were to be installed. Acknowledgement/Funding Funding for this study was provided by the Jaap Schouten Foundation and Erasmus MC Efficiency Research grant